Digital Commons Network^™

Investigating Pituitary Specific Transcription Factor-1 (Pit-1) In Neuronal Development In The Sea Anemone Cnidarian Nematostella Vectensis, Emily Ye

2026 Research Poster Competition

In bilaterians — animals with bilateral symmetry, like vertebrates and insects — the pituitary specific transcription factor-1 (pit-1) is essential for regulating growth hormone and prolactin expression in the pituitary gland. However, in non-bilaterians, the ancestral function of pit-1 remains unknown. Cnidarians, such as the sea anemone Nematostella vectensis, form a sister group to bilaterians and lack a pituitary gland, making them a powerful model for investigating the early evolutionary role of conserved developmental genes, like pit-1.Using CRISPR-mediated gene editing, pit-1 knockout mutants — anemones without the pit-1 gene — were generated, and their transcriptomic, cellular, and behavioral phenotypes were …

Effect Of Organic Vs Inorganic Zinc Sources In Beef Cattle Diets During Gestation On Calf Immune Function And Colostrum Quality, Naija Sharpley

2026 Research Poster Competition

The objective of this study is to determine the effect of zinc supplementation in cattle feed on beef cattle during gestation and the influences of the trace mineral zinc on colostrum and calf immunocompetence measuring immunoglobulin concentrations and body weight. Cow-calf systems rely on the effectiveness and consistency of their nutritional intake. Beef cattle are fed forages and grain alongside specific minerals and supplements to meet nutritional requirements. The effectiveness of these trace minerals added to the diet helps to ensure that the animal gets the most out of its feed and the producer gets the most out of the …

Investigating The Potential Role Of Horse Flies (Diptera: Tabanidae) In The Mechanical Transmission Of Anaplasma Marginale And Theileria Orientalis To Cattle In Northwest Arkansas, Catherine Harrison

2026 Research Poster Competition

The cattle industry in Arkansas plays a significant role in the state’s agricultural economy; however, two emerging infectious diseases pose a threat to cattle health, producer livelihood, and animal welfare. The two diseases, anaplasmosis and theileriosis, are caused by organisms that enter the host’s bloodstream and infect red blood cells, leading to destruction of said cells. The shared symptoms of both diseases are fever, weakness, anemia (low red blood cell count), reduced productivity, weight loss, and possibly death. An important difference between symptoms is that, unlike anaplasmosis, theileriosis can cause abortion in cattle. Both diseases are known to spread through …

Differences In Cytokine Mrna Expression At The Site Of Primary And Secondary Vaccinations With Herpesvirus Of Turkeys (Hvt) In Egg-Type Chickens., Allie Bowerman

2026 Research Poster Competition

Marek’s disease, a lymphoma causing virus, remains a major concern in poultry production systems. Although vaccination with live herpesvirus of turkeys (HVT) is crucial for controlling this disease, information on how the vaccine drives local/tissue immune responses that lead to protective immunity is limited. Using the growing feather (GF) in vivo bioassay, we assessed local cytokine mRNA expression following primary and booster intradermal (i.d.) HVT vaccinations in egg-type chickens. For this, six 9-week-old and six 19-week-old Light-brown Leghorn (LBL) pullets were i.d. injected into the pulp of growing feathers (GF; 10 µL/GF; 16 GFs/bird) with a primary (V1) or secondary …

Enhancing Prosthetic Hand Training Through A Virtual Reality–Based Framework Integrated With The Coapt Control System., Iruoghene Ojoh

2026 Research Poster Competition

Enhancing Prosthetic Hand Training Through a Virtual Reality–Based Framework  Integrated with the Coapt Control System. Ojoh, I.1,2, Shell, A.1,  Asbee, J.1, Aguilar, D.1 ,Abbas, J.1,2,   1Institute for Integrative and Innovative Research, University of Arkansas, Fayetteville, AR;  2Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR  Introduction: Advances in upper-limb prosthetic hardware have greatly improved strength, durability, and mechanical performance; however, achieving intuitive control of EMG-based myoelectric prosthetic hands remains a significant challenge for individuals with trans-radial amputations. These devices rely on electromyography (EMG) signals generated by residual forearm muscles, which require consistent and well-coordinated muscle activation. Many users experience difficulty …

Hybridized-Highway Infrastructures, Will Sutton

2026 Research Poster Competition

This research explores highways and their evolving functions through hybrid programming, from the modern era to the present day. As early as 1916, the federal government began funding state construction of the National Highway System. From this point onward, by design, highways became redundant and homogenized networks of automobile movement, crystallizing their function. Despite this, there are global examples of architecturally utilizing space within, above, or below highway infrastructures that hybridize their function beyond vehicular movement. I am currently studying hybridized-highway infrastructures through a literature review that examines them through the lenses of underutilized space associated with highways, the roles …

"Leafing" Through The Chinese Opera: Phytopoetics In The Peony Pavilion, Madison Bussell Escoto

2026 Research Poster Competition

Ornamental flowering plants have been instrumental symbols in literature across all times and cultures. I’m examining why flowers are such perceptual stimulants, sexual symbols, and literary agents. Through the lens of Joela Jacob’s term “phytopoetics,” which describes the impact of plant life on the human imagination and culture; botany; and literary scholarship, I will look closely at this phenomenon in The Peony Pavilion, a Chinese opera from 1598 which features the first recognized complex and convincing female protagonist in world literature. Exploring “the garden” as a place, I will present the embodied, sensory, and relational elements of the human-flower relationship …

Blood Flow Regulates Metabolism In Hematopoietic Development, Pamela L Wenzel

Faculty, Staff and Student Publications

Blood flow modifies oxygen availability and biomechanical forces within the vasculature of the embryo as the hematopoietic system develops. The aorta-gonad-mesonephros (AGM) envelops the largest artery in the body and is a critical site for the emergence of hematopoietic stem cells (HSCs). Herein, I discuss the role of hypoxia-inducible factors (HIFs) and force as determinants of metabolism and fate determination. To address the effects of blood flow on hematopoietic development, I employ mouse embryo models and biomimetic culture. Real-time cell metabolic analyses show that oxygen consumption rates (OCR) and extracellular acidification rates (ECAR) are altered by flow in cultures of …

Comparative Evaluation Of Hplc And Capillary Electrophoresis In Intestinal Permeability Of Oseltamivir Phosphate Via Single-Pass Intestinal Perfusion (Spip) Method, Senem Şanli, Gülpembe Halay, Mustafa Sinan Kaynak, Nurullah Şanlı

Arts & Sciences Faculty Publications

Introduction: Oseltamivir phosphate (OP), a widely used antiviral prodrug for influenza, requires accurate Biopharmaceutics Classification System (BCS) classification to inform formulation and bioequivalence decisions. Despite its high solubility, the permeability characteristics of OP remain inadequately defined. Methods: This study evaluated the intestinal permeability of OP using the in situ Single-Pass Intestinal Perfusion (SPIP) model in male Sprague Dawley rats. Two validated analytical methods - High-Performance Liquid Chromatography (HPLC) and Capillary Zone Electrophoresis (CZE) were developed and compared. Metoprolol tartrate served as the high-permeability reference standard, and phenol red was used to monitor water flux. Permeability coefficients (Peff) were calculated after …

Understanding Community-Defined Success Of Urban Community Gardens, Josephine H. Laprad

Master of Urban and Regional Planning Capstone Projects

No abstract provided.

Planning For Equitable And Transparent Outdoor Recreation Permitting Within The James River Park System, Sarah J. Girard

Master of Urban and Regional Planning Capstone Projects

The City of Richmond has experienced an imbalance within the current special event permitting process for the Department of Parks, Recreation, and Community Facilities. Park users are not reporting sizeable events being held within the James River Park System, which has caused concern pertaining to environmental and societal impacts. The current permitting process lacks depth and clarity that could be solved by beginning with expanding park user data. This gap of data is the missing piece for the City to be able to make informed future decisions based on a wide array of stakeholder input and tangible visitor use metrics.

Substance Use Behaviors And Treatment Engagement In Individuals With Severe Psychopathology With And Without Comorbid Obesity, Rachel M. Madera-Arnold

Theses and Dissertations

Research has found significantly higher rates of both substance use and obesity among individuals with SMI compared to population samples which in turn can lead to worsening health outcomes. Despite this, there is limited research on the co-occurrence of obesity, substance use, and SMI and how these conditions may interact to affect patient outcomes. In addition, there are many gaps in the research regarding the relationship between substance use and body weight, appetite and/or eating behaviors. This study conducted a secondary analysis of the NSDUH 2021 survey that characterized substance use and disorders among individuals who had severe psychopathology, examined …

Environmental Monitoring In Shallow Lakes: Public Health Threats In Urban Waters, Kyleigh E. Johnson

Theses and Dissertations

Lakes are an integral part of urban and suburban communities, providing ecological, recreational, and public health benefits. Many of these lakes are located in densely populated areas and are subject to urban influences on water quality. Algal toxins and Escherichia coli are two common recreational concerns. Algal toxins come from harmful algal blooms that are influenced by nutrient availability and temperature, while bacteria are often introduced through run-off and animal waste. Sampling every 3-4 weeks from May-October 2025 allowed for the assessment of seasonal patterns and site-specific differences across nine lakes in the Richmond area. The highest bacterial concentrations appeared …

Absolute Quantification And Identification Of Rna From Rna-Lipid Nanoparticles Using High Resolution Mass Spectrometry, Jason C. Funderburk

Theses and Dissertations

RNA therapeutics are a rising drug category with potential use for a range of conditions encompassing infectious diseases to therapies for cancer, diseases, and genetic disorders. RNA-lipid nanoparticles (RNA-LNPs) are the prominent delivery method for these therapeutics approved products include mRNA vaccines and polyneuropathy treatments. The emergency use authorizations and orphan drug status of current RNA-LNP drugs has allowed approval without finalization of the regulatory analytical procedures for quality monitoring. The objective of the study was to develop an LC-MS assay to simultaneously measure identity and concentration of two therapeutically relevant intact RNA constructs extracted from RNA-LNPs to enhance quality …

Musings Of A Dyke: Reimagining A Lesbian Past To Support A Lesbian Future, Tori Mitchell

Theses and Dissertations

This thesis interrogates the heterosexist bias inherent in historical narratives by recontextualizing myth, biblical accounts, folklore, and art history through a dedicated lesbian lens. Utilizing oil painting as my primary medium,  I construct a metafictional world–a pseudo-historical space where the foundational assumption is that every figure is a lesbian until proven otherwise. This inversion serves as a direct counter-narrative to the default lens of cis heteronormativity typically applied to the past. Within this world, I “lesbianize” the traditional icons of Western culture: the heroes, the symbols, and the deities.

My practice navigates the tension between reinvention and extinction, viewing both …

In Search Of The Soul Of Creativity: Authorship, Agency, And Meaning In Refractive Collaboration With Generative Ai, Fatima Nazir

Theses and Dissertations

When images can be generated in seconds, what remains uniquely human in the act of creation? In Search of the Soul of Creativity: Authorship, Agency, and Meaning in Refractive Collaboration with Generative AI investigates where authorship, agency, and meaning reside within design practices mediated by generative AI. Rather than using AI to produce predictable results, this research deliberately relinquishes control to observe how generative systems interpret language through their own learned associations. Through a practice-led investigation across four generative models within the Higgsfield platform, user prompts were progressively shortened from full sentences to single words, revealing recurring patterns and cultural …

The Ethereal Being That Is Me, And Maybe You, Hwiy Chang

Theses and Dissertations

The Ethereal Being That Is Me, and Maybe You is a 23-minute video collection of short stories accompanied by an installation at the Institute for Contemporary Art at Virginia Commonwealth University. This thesis explores the work’s creation as a visual and narrative meditation on self-transformation, drawing from personal experiences in therapy and philosophical texts including Carl Jung’s concept of the unconscious. The paper examines how each story represents a distinct stage of transformation—from recognizing patterns to confronting setbacks to reshaping internal dialogue—and how watercolor’s fluid, unpredictable nature serves as a visual metaphor for the process of change. The installation component …

Walking And Wondering, Helen T. Tran

Theses and Dissertations

My thesis approaches walking as a form of inquiry and the Flood Wall as a site open to reinterpretation. I believe that the way we walk changes the way we observe and experience the world around us. This contrast between purposeful and leisurely walking reveals how time and intention shape our awareness of space. When walking is no longer dictated by urgency, it invites observations and questions. Slowing our pace allows curiosity to emerge, which aligns with my design ethos of asking questions as a foundation for understanding and creating meaningful experiences.

The Flood Wall’s emphasis on uninterrupted movement prioritizes …

Pingbongbilladingdong: Abjection And Comedy In Art, Leroy A. Winter

Theses and Dissertations

As of late, my work has dealt with themes of collapse and comedy, pertaining specifically to faded ideals of individualism in art. My thesis installation, titled Pingbongbilladingdong, is a testament to this tension, portraying a reconstruction of the disheveled chaos of the artist’s studio. In this paper, I use this installation as a means to further explore the ways that abjection and comedy intersect in art, and how myself and others repurpose the faded glamor of Ab-Ex as a means to probe this overlap. Serving as an allegory for my experience with the studio, Pingbongbilladingdong presents an image of the …

Commissioning & Daily Qa Of Converted Linac For Electron Flash, Tomaj Javidtash

Theses and Dissertations

Ultra-high dose rate (FLASH) radiotherapy has demonstrated promising normal tissue sparing in preclinical studies; however, the lack of standardized dosimetry, commissioning, and quality assurance (QA) methodologies remains a major barrier to its reproducible and safe implementation. In particular, conventional clinical commissioning and QA protocols are not directly applicable at FLASH dose rates due to challenges associated with detector response, dose-per-pulse effects, and beam control limitations.

This thesis presents the commissioning of a converted Varian 21EX linear accelerator for electron FLASH operation within the Division of Medical Physics at the Virginia Commonwealth University (VCU) Department of Radiation Oncology. Comprehensive beam characterization …

Within The Ruin: A Modern Brewery Rebirth, Karim Asarzadeh

Theses and Dissertations

This thesis project focuses on the revitalization of the historic ruins of the James River Steam Brewery in Richmond, Virginia. The project transforms the forgotten industrial structure into a modern brewery with a second-floor restaurant addition and community gathering spaces while preserving the historic masonry ruins. It showcases a holistic design approach that considers all aspects of the building, including its connection to the urban context and landscape, as well as its architecture, interiors, and furniture. The project demonstrates how a holistic design approach can create stronger spatial connections and more cohesive environments. In particular, it offers a strategy for …

In-Between Echoes, Jiayi Liang

Theses and Dissertations

In this dissertation, I explore memory, diaspora, labor, and intergenerational trauma through constructed photography and experimental film. Informed by Homi K. Bhabha’s concept of the Third Space, I examine how identity is shaped through displacement, cultural negotiation, and inherited memory. Drawing from my relationship with my grandmother and my experience as a Chinese woman living in diaspora, I consider labor as both survival and care, tracing how domestic gestures and emotional structures continue across generations. Through collage, reconstruction, and animation, I rework fragments of family archives, colonial landscape imagery, and personal photographs to address grief, racialized perception, belonging, and the …

Profile: More Is Morris, Communications And Marketing

Profile (1996-)

In this Issue: New Name and New Director for the AgCountry Challenge ; Salute to Scholarships ; Gift to Not Only Enhance Cougar Sports Center But Entire Community ; Lucy Imholte's Lasting Legacy Honored Through Sculpture ; From Dining Hall to Third Floor Behmler: Rodriguez '87 is Eighth Chancellor ; Partnership Pilots New Energy Storage Technology on Campus ; Faculty and Staff Awards ; Van Wey Named Fulbright Finalist ; UMN Morris Receives Carnegie Community Engagement Classification ; Public Lecture, Telescope Viewing Part of SCOPES Conference ; UMN Morris Adds $165.3 Million to Minnesota's Economy Each Year ; PBS Documentary …

A Chromosome-Level Assembly And Functional Genomic Resources For The Model Annelid Capitella Teleta, Billie E. Davies, Paul Gonzalez, Abhinav Sur, Jingcheng Wei, Tom Frankish, Jimena Montagne, Allan M. Carrillo-Baltodano, Kero Guynes, Yan Liang, Rory D. Donnellan, Travis Moreland R., Sumeeta Singh, Suiyuan Zhang, Reynold Yu, Tyra G. Wolfsberg, Néva Meyer, Elaine C. Seaver, Andreas D. Baxevanis, José M. Martín-Durán

Biology

The polychaete Capitella teleta is a primary model for evolutionary developmental biology, comparative genomics, conservation, and ecotoxicology. Although it was the first polychaete genome sequenced, the original assembly is outdated by modern standards. Here, we combine long-read and short-read sequencing with Hi-C chromatin conformation capture to assemble chromosome-level nuclear and mitochondrial genomes of the laboratory strain of C. teleta. This reference assembly accurately reflects the expected genome size (∼243.6 Mb) and contains a highly complete, evolutionarily conserved gene repertoire. Notably, the nuclear and mitochondrial genomes are heavily rearranged, indicating a decoupling between gene family repertoire and chromosomal evolution. The analyses …

Embedded Tense And The Problem Of Acquisition, Sam Alxatib, Spencer Caplan

Publications and Research

What we hope to do is pose questions that, to our knowledge, have not received attention in the literature. The broad form of the question is all too familiar: how do speakers of a language—say, English—come to possess the grammatical knowledge that they demonstrate? The questions that guide this paper are narrow instances of this broad one, narrowed in three ways. First, they concern three particular languages: Japanese, English, and Russian. Second, they concern tenses specifically, and more specifically still, constructions containing embedded tenses. Third, they concern the semantics of tense. The learning challenge of interest to us is not …

The Federal Rules Of Evi-Dance: Exploring And Reimagining Evidence Law Through Music, And Proposing Amendments To Rule 604, Brian C. Potts

Faculty Articles

Every trial has a rhythm and a flow. Every trial is a performance. This article extends the literature on law and music further into the field of evidence. I offer a new exploration and reimagining of the Federal Rules of Evidence through leitmotivs. I contend that leitmotivs—musical calling cards—reify principles of evidence law. As I spin these leitmotivs, I propose two amendments to Rule 604 regarding the oath for courtroom interpreters. I propound a new critique explaining how and why courts are wrong when they often claim “Daubert did not work a ‘seachange’ over federal evidence law.” I tender two …

Evaluating Willow Establishment With Biochar For Remediation Of Mine Waste Soils: Amendment Ph Determines Plant Biomass And Metal Mobility, Madeline R. Webb

Dissertations, Master's Theses and Master's Reports

Heavy metal contaminated mine tailings (“stamp sands”) from historic copper mining inhibit plant establishment and contribute to ongoing metal contamination. Biochar amendments may enhance plant growth and reduce metal mobility in highly permeable mine waste soils, but the efficacies of different application methods or biochar sources and composition are uncertain. We evaluated different biochar sources (neutral or alkaline pH) and application methods (either mixed or layered) for planted willow growth, moisture retention, and metal mobility. A 10-week growth chamber experiment assessed plant performance, heavy metal content and heavy metal mobility in soil leachates and plant tissues. Biochar pH was the …

Socialization Interventions For Older Adults In Assisted Living Facilities: A Systematic Review, Anoop S. Muvva

Honors Undergraduate Theses

Older adults, defined as individuals over the age of 65, are a growing population in the United States, with projections estimating this group will reach approximately 80 million persons by 2050. Over 90% of older adults are diagnosed with a chronic condition, which can make it difficult to carry out the activities of daily living. As a result, some older adults reside in assisted living facilities, where dedicated staff provide daily support. However, issues in the delivery of care within these settings, including unmet socialization needs and complications among care staff, may contribute to social isolation. Programs designed to address …

Comparative Spatial Biology: A Cross-Species Analysis Of Canine Oral Cancers As Models For Human Disease, Ram Pradhyumnan

Honors Undergraduate Theses

Oral squamous cell carcinoma (OSCC), one of the most common malignancies of the oral cavity, remains a clinically challenging disease due to its aggressive behavior, late-stage diagnosis, and limited improvements in therapeutic outcomes over recent decades. A significant barrier to progress in OSCC research and treatment is the lack of suitable preclinical models that recapitulate the complexity and natural progression of the disease. Most current models—including cell lines, xenografts, and genetically engineered mice—fail to capture key features such as the spatial organization of tumor epithelium, interactions with an intact immune system, and the stepwise evolution from normal mucosa to invasive …

Who Makes The Jury? Demographics And Decision-Making In The Jury Process., Ana B. Pons

Honors Undergraduate Theses

Within the American judicial system, juries have played a central role in promoting representation and fairness in the courtroom. However, limited information exists on whether prosecutorial decisions during jury selection, jury composition, or jury behavior differ based on the sex, race/ethnicity, type of case, political ideology, or geographic location of potential jurors. Following PRISMA guidelines, this scoping review synthesizes 48 peer-reviewed articles published between the 1940s and 2026 to examine whether prosecutorial decision-making and jury outcomes vary based on the sex, race/ethnicity, type of case, political ideology, or geographic location of potential jurors. Findings indicated that men are disproportionately selected …