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Articles 117721 - 117750 of 734961
Full-Text Articles in Entire DC Network
The Montclarion, December 2, 2021, The Montclarion
The Montclarion, December 2, 2021, The Montclarion
The Montclarion
Student Newspaper of Montclair State University
Covid-19'S Impact On Communication Practices In The Animal Welfare Nonprofit Sector, Tiffany M. Davis
Covid-19'S Impact On Communication Practices In The Animal Welfare Nonprofit Sector, Tiffany M. Davis
Master of Arts in Professional Writing Capstones
Historically, writing and communication practices have been vital components in the nonprofit sector. With the rise of the COVID-19 pandemic, the writing and communication practices within the nonprofit sector have been forced to adapt and change for organizations to continue disseminating their missions and continuing fundraising. Specifically, animal welfare nonprofit organizations have had to shift their communication practices in the wake of the virus. This capstone aims to answer questions about the value of writing and communication practices, and also answer research questions about the effects of COVID-19 on the animal welfare nonprofit sector. Through secondary and primary research, in …
High-Throughput Functional Analysis Of Cftr And Other Apically Localized Proteins In Ipsc-Derived Human Intestinal Organoids, Sunny Xia, Zoltán Bozóky, Michelle Di Paola, Onofrio Laselva, Saumel Ahmadi, Jia Xin Jiang, Amy L Pitstick, Chong Jiang, Daniela Rotin, Christopher N Mayhew, Nicola L Jones, Christine E Bear
High-Throughput Functional Analysis Of Cftr And Other Apically Localized Proteins In Ipsc-Derived Human Intestinal Organoids, Sunny Xia, Zoltán Bozóky, Michelle Di Paola, Onofrio Laselva, Saumel Ahmadi, Jia Xin Jiang, Amy L Pitstick, Chong Jiang, Daniela Rotin, Christopher N Mayhew, Nicola L Jones, Christine E Bear
Open Access Publications
Induced Pluripotent Stem Cells (iPSCs) can be differentiated into epithelial organoids that recapitulate the relevant context for CFTR and enable testing of therapies targeting Cystic Fibrosis (CF)-causing mutant proteins. However, to date, CF-iPSC-derived organoids have only been used to study pharmacological modulation of mutant CFTR channel activity and not the activity of other disease-relevant membrane protein constituents. In the current work, we describe a high-throughput, fluorescence-based assay of CFTR channel activity in iPSC-derived intestinal organoids and describe how this method can be adapted to study other apical membrane proteins. Specifically, we show how this assay can be employed to study …
Mechanical Overload-Induced Muscle-Derived Extracellular Vesicles Promote Adipose Tissue Lipolysis, Ivan J. Vechetti Jr, Bailey D. Peck, Yuan Wen, R Grace Walton, Taylor R. Valentino, Alexander P. Alimov, Cory M. Dungan, Douglas W. Van Pelt, Ferdinand Von Walden, Bjorn Alkner, Charlotte A. Peterson, John J. Mccarthy
Mechanical Overload-Induced Muscle-Derived Extracellular Vesicles Promote Adipose Tissue Lipolysis, Ivan J. Vechetti Jr, Bailey D. Peck, Yuan Wen, R Grace Walton, Taylor R. Valentino, Alexander P. Alimov, Cory M. Dungan, Douglas W. Van Pelt, Ferdinand Von Walden, Bjorn Alkner, Charlotte A. Peterson, John J. Mccarthy
Department of Nutrition and Health Sciences: Faculty Publications
How regular physical activity is able to improve health remains poorly understood. The release of factors from skeletal muscle following exercise has been proposed as a possible mechanism mediating such systemic benefits. We describe a mechanism wherein skeletal muscle, in response to a hypertrophic stimulus induced by mechanical overload (MOV), released extracellular vesicles (EVs) containing muscle-specific miR-1 that were preferentially taken up by epidydimal white adipose tissue (eWAT). In eWAT, miR-1 promoted adrenergic signaling and lipolysis by targeting Tfap2α, a known repressor of Adrβ3 expression. Inhibiting EV release prevented the MOV-induced increase in eWAT miR-1 abundance and expression of …
The Shortcomings Of Corporate Accountability In Post-Conflict Colombia: Land, Rivers And Animals, Isabella Ariza Buitrago, Luisa Gomez Betancur
The Shortcomings Of Corporate Accountability In Post-Conflict Colombia: Land, Rivers And Animals, Isabella Ariza Buitrago, Luisa Gomez Betancur
Biennial Conference: The Social Practice of Human Rights
Although the notion of sustainable peace requires acknowledging the role played by all actors, transitional processes around the world have inadequately addressed or completely ignored the direct and indirect participation of economic actors. In particular, Colombia's transitional justice regime left out corporations entirely. A skillshare between Colombian lawyers and US-based human rights attorneys showed some of the gaps that let corporations continue in impunity for profiting, benefiting from, or directly financing the conflict. Other than harming and deeply fracturing communities, the shortcomings of corporate accountability in post-conflict Colombia also leave land, rivers, and animals without redress. This paper explores some …
Assessment Of Conduct Disorder In Primary Care: Integrative Review, Chantel M. Kilford
Assessment Of Conduct Disorder In Primary Care: Integrative Review, Chantel M. Kilford
DNP Qualifying Manuscripts
Conduct disorder and behavioral problems in children are the 6th most prominent childhood health disorder within the United States of America. Early recognition and interventions have shown to improve outcomes and reduce lifelong adult sequela. Evidence suggests that primary care providers are not confident or knowledgeable about identification and assessment of the disorder. The manuscript examines the prevalence, co-morbidities, trajectories, mortality risk and outcomes of conduct disorder. Health disparities and diagnostic stigma are also addressed. Additionally, the manuscript provides primary care providers with evidence-based research and recommendations for prompt identification and screening. Conduct disorder has devasting individual, social, and …
Impacts Of Deepwater Horizon On Fish And Fisheries: What Have We Learned About Resilience And Vulnerability In A Coupled Human-Natural System?, S.A. Murawski, C.B. Paris, Tracey Sutton, M. Cockrell, S. O'Farrell, J. Sanchirico, E. Chancellor, L. Perruso
Impacts Of Deepwater Horizon On Fish And Fisheries: What Have We Learned About Resilience And Vulnerability In A Coupled Human-Natural System?, S.A. Murawski, C.B. Paris, Tracey Sutton, M. Cockrell, S. O'Farrell, J. Sanchirico, E. Chancellor, L. Perruso
Marine & Environmental Sciences Faculty Proceedings, Presentations, Speeches, Lectures
The Deepwater Horizon (DWH) oil spill occurred in a region of the Gulf of Mexico (GoM) supporting abundant, diverse and valuable communities of fishes and fishers. The economy of the northern GoM is inextricably tied to the natural resource bases of the region (tourism, fishing, oil and gas, etc.) and thus the coupling between the human and ecological systems is tight and subject both feed-back and, to some extent, feed-forward controls. Management actions taken during the 87-day DWH spill incident included the closure of over 280,000 km2 of productive fishing area (about 1/3 of USA federal waters in the …
Full Time Faculty Handbook, Sacred Heart University
Full Time Faculty Handbook, Sacred Heart University
Handbooks & Factbooks
Revised, Approved by the Board of Trustees on December 3, 2021.
Novel Approaches For Enhancing Cell Survival And Function In Vivo, Ou Wang
Novel Approaches For Enhancing Cell Survival And Function In Vivo, Ou Wang
Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research
FDA has approved several cell-based therapeutics and hundreds of cell therapy clinical trials are ongoing. Cells will be a significant type of medicine after small molecule and protein drugs. However, several obstacles need to be addressed to achieve the widespread use of cellular therapeutics. The first challenge is the low efficacy of cell transplantation due to low retention, survival, integration, and function of cells in vivo. The second challenge is producing a massive number of cells for clinical treatment with cost-effectively and reproducibly technologies.
In this thesis, we proposed and investigated two approaches to address these challenges. To begin …
Kingfish Neurocranium, Kaden R. Mackey, David Kerstetter
Kingfish Neurocranium, Kaden R. Mackey, David Kerstetter
All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series
This is the skull of a kingfish with the nasal bone included.
Grey Triggerfish (Balistes Capriscus) Neurocranium, Madelynn Sampson, Hailey Levine, David W. Kerstetter
Grey Triggerfish (Balistes Capriscus) Neurocranium, Madelynn Sampson, Hailey Levine, David W. Kerstetter
All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series
Grey Triggerfish (Balistes capriscus) neurocranium preparation by Madelynn Sampson and Hailey LeVine.
Zoom In Closer, Ying Chiun Lee
Zoom In Closer, Ying Chiun Lee
Theses
Zoom In Closer explores ideas of sensuality through glass and narratives. I am interested in the material qualities of glass, including translucency, fluidity, and warmth; and how these qualities can be translated into languages of intimacy. This thesis is based on personal experience and scholarly research on the enigma of female sexual desires. Zoom In Closer is a body of work that utilizes glass objects, glass processes, films, illustrations, and photography that question what does it means to live authentically despite the influences of rape culture.
Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An
Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An
School of Computing: Dissertations, Theses, and Student Research
Pancreatic cancer is the fourth leading cause of cancer death in the United States and the 5-year survival rate is only 5% to 10%. There are only a few non-specific symptoms associated with the early-stage cancer, therefore most patients are diagnosed in a late stage. Due to the lack of effective treatments and the fact that the early stage has a 39% 5-year survival rate, the biggest hope to control this disease is early detection. Therefore, discovery of effective and reliable non-invasive biomarkers for early detection of pancreatic cancer has been a major topic. Very recently, exosomal microRNAs have become …
The Puppy In The Polka Dot Pajamas: Animating Children's Literature Through Short Film, Grace Phillips
The Puppy In The Polka Dot Pajamas: Animating Children's Literature Through Short Film, Grace Phillips
Honors Projects
The following written defense describes the guiding research, methodologies, and end results of my yearlong project - creating a digital children’s book and an accompanying short film. The project was initially inspired by an event at home in which my family was laughing at our small dog for the way he looked after we dressed him in pajamas, after which my dad made a comment that it would be heinous of us to treat a human being the same way. This comment inspired me to adopt my own approach as to how humans can learn from the animal kingdom. The …
Bile Acid Profiling Reveals Distinct Signatures In Undernourished Children With Environmental Enteric Dysfunction, Xueheng Zhao, Kenneth D R. Setchell, Rong Huang, Indika Mallawaarachchi, Lubaina Ehsan, Edward Dobrzykowski Iii, Junfang Zhao, Sana Syed, Najeeha Talat Iqbal, Junaid Iqbal, Kamran Sadiq, Sheraz Ahmed, Syed Asad Ali
Bile Acid Profiling Reveals Distinct Signatures In Undernourished Children With Environmental Enteric Dysfunction, Xueheng Zhao, Kenneth D R. Setchell, Rong Huang, Indika Mallawaarachchi, Lubaina Ehsan, Edward Dobrzykowski Iii, Junfang Zhao, Sana Syed, Najeeha Talat Iqbal, Junaid Iqbal, Kamran Sadiq, Sheraz Ahmed, Syed Asad Ali
Department of Paediatrics and Child Health
Background: Intestinal inflammation and malabsorption in environmental enteric dysfunction (EED) are associated with early childhood growth faltering in impoverished settings worldwide.
Objectives: The goal of this study was to identify candidate biomarkers associated with inflammation, EED histology, and as predictors of later growth outcomes by focusing on the liver-gut axis by investigating the bile acid metabolome.
Methods: Undernourished rural Pakistani infants (n = 365) with weight-for-height Z score (WHZ) < -2 were followed up to the age of 24 mo and monitored for growth, infections, and EED. Well-nourished local children (n = 51) were controls, based on consistent WHZ > 0 and height-for-age Z score (HAZ) > -1 on 2 consecutive visits at 3 and 6 mo. Serum bile acid (sBA) profiles were measured by tandem MS at the ages of 3-6 …
Development And Characterization Of A Decellularized Neuroinhibitory Scaffold Containing Matrix Bound Nanovesicles, Logan Piening
Development And Characterization Of A Decellularized Neuroinhibitory Scaffold Containing Matrix Bound Nanovesicles, Logan Piening
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Chronic low back pain (LBP) is a leading cause of disability but treatments for LBP are limited. Degeneration of the intervertebral disc leads to loss of neuroinhibitory sulfated glycosaminoglycans (sGAGs) which allows nerves from dorsal root ganglia (DRG) to grow into the core of the disc, leading to pain. Current treatments for LBP involve drugs that do not target the source of the pain and lack long term efficacy or use invasive surgeries with high complication rates. Treatment with a decellularized tissue scaffold that contains neuroinhibitory components may inhibit nerve growth and prevent disc-associated LBP. Here, a decellularized nucleus pulposus …
International Engagement Weekly Newsletter, December 3, 2021, University Of Northern Iowa. Office Of International Engagement.
International Engagement Weekly Newsletter, December 3, 2021, University Of Northern Iowa. Office Of International Engagement.
Office of International Engagement newsletter
Inside this Issue:
--- Good Luck on Finals!
--- Student Wellness Services De-Stress Days
--- "It's a Wonderful Life" Film Screening
--- Weekly Coffee Hour
--- Visit the Amana Colonies with OIE
--- Ethnic Student Promoters is now accepting applications for the Spring semester
--- Free Winter Clothing
--- UNI's Interactive Digital Studies
--- Immigration Tip
Usage Statistics: Project Counter R5 Ir_M1 Report Fy2021 - Multimedia Item Requests, Andrée Rathemacher
Usage Statistics: Project Counter R5 Ir_M1 Report Fy2021 - Multimedia Item Requests, Andrée Rathemacher
Technical Services Reports and Statistics
Project COUNTER R5 Report IR_M1 for the University of Rhode Island for the period from July 1, 2020 - June 30, 2021. The IR_M1 report is defined as "Multimedia Item Requests." This report presents an annual total only and only includes those platforms successfully configured for automated harvesting via SUSHI.
File for download is Excel spreadsheet generated by Alma Analytics.
Results:
Total Item Requests - 6,292
Mahi Mahi (Coryphaena Hippurus) Neurocranium, Alexia J. Hilber, Caileigh Craddock, Kiara Belanger, David W. Kerstetter
Mahi Mahi (Coryphaena Hippurus) Neurocranium, Alexia J. Hilber, Caileigh Craddock, Kiara Belanger, David W. Kerstetter
All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series
Neurocranium from Mahi Mahi (Coryphaena hippurus), collected in 3/2021 by Katerina Sawickji
Genomic Epidemiology Of Clostridium Difficile Colonization And Transmission In An Intensive Care Unit Cohort, Brianne Ciferri
Genomic Epidemiology Of Clostridium Difficile Colonization And Transmission In An Intensive Care Unit Cohort, Brianne Ciferri
Dissertations and Theses
Abstract
Genomic epidemiology of Clostridium difficile colonization and transmission in an intensive care unit cohort
by Brianne Ciferri, MPH
Advisor: C. Mary Schooling, PhD
Introduction: Clostridiodes difficile (C. difficile) is a leading cause of healthcare associated infections (HAI) in the United States and responsible for an estimated incidence of 223,900 cases and 12,800 deaths per year1,2. C. difficile can cause gastrointestinal illness with symptoms ranging from mild diarrheal illness to a life-threatening condition. C. difficile is an opportunistic pathogen in which spores can live in an undisturbed dormant state within the intestinal tract and become …
Gretchen Ruth Art399 Portfolio, Gretchen Ruth
Gretchen Ruth Art399 Portfolio, Gretchen Ruth
Professional Practices (ART 399)
My work comes from a place of tension between trying to understand the world and being understood. My current focus is making work that has more centralized and serious concepts. Despite some naturalistic elements that are often seen throughout my works,
I intentionally combine these elements along with imagery that brings the viewer to a made-up or dream-like reality . One of the most important aspects to these types of works, especially more recently, is my use of color. Throughout a lot of my work, I utilize form and proportion as well as color to emphasize the ambience of the …
Editorial: Diversifying Farming Systems For Adaptive Capacity, Margiana Petersen-Rockney, Timothy Bowles, Selena Ahmed, Patrick Baur
Editorial: Diversifying Farming Systems For Adaptive Capacity, Margiana Petersen-Rockney, Timothy Bowles, Selena Ahmed, Patrick Baur
Fisheries, Animal and Veterinary Sciences Faculty Publications
No abstract provided.
Whole-Genome Sequencing-Based Phylogeny, Antibiotic Resistance, And Invasive Phenotype Of Escherichia Coli Strains Colonizing The Cervix Of Women In Preterm Labor., Marvin Williams, Alyssa B. Jones, Amanda L. Maxedon, Jennifer E. Tabakh, Cindy B. Mccloskey, David E. Bard, Daniel P. Heruth, Susana Chavez-Bueno
Whole-Genome Sequencing-Based Phylogeny, Antibiotic Resistance, And Invasive Phenotype Of Escherichia Coli Strains Colonizing The Cervix Of Women In Preterm Labor., Marvin Williams, Alyssa B. Jones, Amanda L. Maxedon, Jennifer E. Tabakh, Cindy B. Mccloskey, David E. Bard, Daniel P. Heruth, Susana Chavez-Bueno
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Escherichia coli is a major neonatal pathogen and the leading cause of early-onset sepsis in preterm newborns. Maternal E. coli strains are transmitted to the newborn causing invasive neonatal disease. However, there is a lack of data regarding the phenotypic and genotypic characterization of E. coli strains colonizing pregnant women during labor.
METHODS: This prospective study performed at the University of Oklahoma Medical Center (OUHSC) from March 2014 to December 2015, aimed to investigate the colonization rate, and the phylogeny, antibiotic resistance traits, and invasive properties of E. coli strains colonizing the cervix of fifty pregnant women diagnosed with …
Christmas At The Printing Press, Sarah Burke Cahalan
Christmas At The Printing Press, Sarah Burke Cahalan
Materials from the University of Dayton Magazine Website
Showing off small press Christmas cards from the Marian Library collection
Assessing The E-Learning Readiness Of Universities In Developing Countries And Expected Obstacles, Abdelrahim Ate, Samar Zaineldeenc, Cai Zhaohui, Yan Zhao
Assessing The E-Learning Readiness Of Universities In Developing Countries And Expected Obstacles, Abdelrahim Ate, Samar Zaineldeenc, Cai Zhaohui, Yan Zhao
Makara Journal of Technology
To benefit from electronic learning (E-learning), organizations should execute considerable upfront analysis to ascertain their E-learning readiness. Studies have demonstrated a range of models that have been adapted, but they are used in developed counties for whom E-learning readiness is elevated. Thus, these models are not valid in growing countries, such as Sudan. Based on a modified model, this research was performed descriptively by applying a questionnaire-based survey method to assess the level of Sudan universities’ readiness in the employment of the E-learning system. This modified model includes social support, technology readiness, attitude toward E-learning, acceptance of E-learning, and individual …
The Centennial Of The Pecking Order: Current State And Future Prospects For The Study Of Dominance Hierarchies, Eli D. Strauss, James P. Curley, Daizaburo Shizuka, Elizabeth A. Hobson
The Centennial Of The Pecking Order: Current State And Future Prospects For The Study Of Dominance Hierarchies, Eli D. Strauss, James P. Curley, Daizaburo Shizuka, Elizabeth A. Hobson
School of Biological Sciences: Faculty Publications
A century ago, foundational work by Thorleif Schjelderup-Ebbe described a ‘pecking order’ in chicken societies, where individuals could be ordered according to their ability to exert their influence over their group-mates. Now known as dominance hierarchies, these structures have been shown to influence a plethora of individual characteristics and outcomes, situating dominance research as a pillar of the study of modern social ecology and evolution. Here, we first review some of the major questions that have been answered about dominance hierarchies in the last 100 years.Next,we introduce the contributions to this theme issue and summarize howthey provide ongoing insight in …
The Arkansas Code And Georgia V. Public.Resource.Org, Daniel Bell
The Arkansas Code And Georgia V. Public.Resource.Org, Daniel Bell
Arkansas Law Notes
The United States Supreme Court decided Georgia v. Public.Resource.Org, Inc. (“PRO”) in late April, 2020, a case with major implications for those who rely on the Arkansas statutes. The case addressed whether extra materials Georgia includes in its official statutes, the annotations, can be copyrighted, or if they are in the public domain and can be freely distributed without permission. The case pitted two important competing interests against each other: the ability of citizens to freely access the official versions of laws of their state, versus the interests of a third-party publisher in being compensated for its work. Arkansas produces …
The Effects Of Chronic Ethanol Exposure On Caenorhabditis Elegans Germline, Andrea Zegarra
The Effects Of Chronic Ethanol Exposure On Caenorhabditis Elegans Germline, Andrea Zegarra
Seton Hall University Dissertations and Theses (ETDs)
Ethanol is the most commonly abused drug in the world. Alcohol consumption increases a number of health risks, morbidity and mortality, and chronic and acute diseases. Some health risks include high blood pressure, stroke, liver disease, cancer, and can include mental health and social problems. Chronic alcohol consumption can lead to learning and memory problems, along with alcohol dependence. Additionally, alcohol consumption has an impact on ovarian reserve, steroid hormone production, sperm quality, fecundity, and fertility treatments. The purpose of this study was to analyze the effects of ethanol exposure on fertility of the N2 wild type as measured by …
Classrooms Into Courtrooms, Naomi M. Mann
Classrooms Into Courtrooms, Naomi M. Mann
Faculty Scholarship
The federal Department of Education’s (DOE) 2020 Title IX Rule fundamentally transformed the relationship between postsecondary schools (schools) and students. While courts have long warned against turning classrooms into courtrooms, the 2020 Rule nonetheless imposed a mandatory quasi-criminal courtroom procedure for Title IX sexual harassment investigatory proceedings in schools. This transformation is a reflection of the larger trend of importing criminal law norms and due process protections into Title IX school proceedings. It is especially regressive at a time where calls for long-overdue criminal justice reform are reaching a boiling point across the nation. Its effects are especially troubling because …