Digital Commons Network^™

The Relevance Of The Five New Laws Of Librarianship To The Development Of Mosque Libraries In Indonesia, Ahmad Amir Aziz

Library Philosophy and Practice (e-journal)

In today's world of information technology disruption, library science must adapt quickly and accurately. The true library will always play an important role as a center of knowledge, including the mosque library, which is a distinct type of library because the majority of its collections are religious in nature. This article intends to discuss the New Five Laws of Librarianship as proposed by Michael Gorman, who revised the Ranganathan concept. The concept will be tested to determine its applicability to the design of the mosque library development, which is tasked with providing services to the surrounding Muslim community. Gorman's principle …

Induction Of Il19 Expression Through Jnk And Cgas-Sting Modulates Dna Damage–Induced Cytokine Production, Sara H. Small, E. Jessica Tang, Ryan L. Ragland, Yaroslava Ruzankina, David W. Schoppy, Rahul S. Mandal, M. Rebecca Glineburg, Zgjim Ustelenca, Daniel J. Powell, Fiona Simpkins, F. Bradley Johnson, Eric J. Brown

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Cytokine production is a critical component of cell-extrinsic responses to DNA damage and cellular senescence. Here, we demonstrated that expression of the gene encoding interleukin-19 (IL-19) was enhanced by DNA damage through pathways mediated by c-Jun amino-terminal kinase (JNK) and cGAS-STING and that IL19 expression was required for the subsequent production of the cytokines IL-1, IL-6, and IL-8. IL19 expression was stimulated by diverse cellular stresses, including inhibition of the DNA replication checkpoint kinase ATR (ataxia telangiectasia and Rad3-related protein), oncogene expression, replicative exhaustion, oxidative stress, and DNA double-strand breaks. Unlike the production of IL-6 and IL-8, IL19 expression was …

Late-Life Exercise Mitigates Skeletal Muscle Epigenetic Aging, Kevin A. Murach, Andrea L. Dimet-Wiley, Yuan Wen, Camille R. Brightwell, Christine M. Latham, Cory M. Dungan, Christopher S. Fry, Stanley J. Watowich

Center for Muscle Biology Faculty Publications

There are functional benefits to exercise in muscle, even when performed late in life, but the contributions of epigenetic factors to late-life exercise adaptation are poorly defined. Using reduced representation bisulfite sequencing (RRBS), ribosomal DNA (rDNA) and mitochondrial-specific examination of methylation, targeted high-resolution methylation analysis, and DNAge™ epigenetic aging clock analysis with a translatable model of voluntary murine endurance/resistance exercise training (progressive weighted wheel running, PoWeR), we provide evidence that exercise may mitigate epigenetic aging in skeletal muscle. Late-life PoWeR from 22–24 months of age modestly but significantly attenuates an age-associated shift toward promoter hypermethylation. The epigenetic age of muscle …

Unravelling Rubber Tree Growth By Integrating Gwas And Biological Network-Based Approaches, Felipe Roberto Francisco, Alexandre Hild Aono, Carla Cristina Da Silva, Paulo S. Gonçalves, Erivaldo J. Scaloppi Junior, Vincent Le Guen, Roberto Fritsche-Neto, Livia Moura Souza, Anete Pereira De Souza

Faculty Publications

Hevea brasiliensis (rubber tree) is a large tree species of the Euphorbiaceae family with inestimable economic importance. Rubber tree breeding programs currently aim to improve growth and production, and the use of early genotype selection technologies can accelerate such processes, mainly with the incorporation of genomic tools, such as marker-assisted selection (MAS). However, few quantitative trait loci (QTLs) have been used successfully in MAS for complex characteristics. Recent research shows the efficiency of genome-wide association studies (GWAS) for locating QTL regions in different populations. In this way, the integration of GWAS, RNA-sequencing (RNA-Seq) methodologies, coexpression networks and enzyme networks can …

Plastic, Pollution, Art, And The Caribbean, Celine Collazo

Theses and Dissertations

The impact of a growing ocean pollution problem can be seen on the trash-filled shores of Caribbean beaches. Through a contextualization of the work of three artists, Tony Capellán, Radamés ‘Juni’ Figueroa, and Alejandro Durán, this paper discusses the cause and effects of such detritus, and possibilities for change.

Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation Of Monocytes And Reduces Il-1Β Secretion By Urate Crystal Stimulated Gout Pbmcs, Sandy Elsayed, Gregory D. Jay, Ralph Cabezas, Marwa Qadri, Tannin A. Schmidt, Khaled A. Elsaid

Pharmacy Faculty Articles and Research

Objectives

To compare phagocytic activities of monocytes in peripheral blood mononuclear cells (PBMCs) from acute gout patients and normal subjects, examine monosodium urate monohydrate (MSU) crystal-induced IL-1β secretion ± recombinant human proteoglycan 4 (rhPRG4) or interleukin-1 receptor antagonist (IL-1RA), and study the anti-inflammatory mechanism of rhPRG4 in MSU stimulated monocytes.

Methods

Acute gout PBMCs were collected from patients in the Emergency Department and normal PBMCs were obtained from a commercial source. Monocytes in PBMCs were identified by flow cytometry. PBMCs were primed with Pam3CSK4 (1μg/mL) for 24h and phagocytic activation of monocytes was determined using fluorescently labeled latex beads. MSU …

Rotavirus Nsp1 Contributes To Intestinal Viral Replication, Pathogenesis, And Transmission, Gaopeng Hou, Qiru Zeng, Jelle Matthijnssens, Harry B Greenberg, Siyuan Ding

Open Access Publications

Rotavirus (RV)-encoded nonstructural protein 1 (NSP1), the product of gene segment 5, effectively antagonizes host interferon (IFN) signaling via multiple mechanisms. Recent studies with the newly established RV reverse genetics system indicate that NSP1 is not essential for the replication of the simian RV SA11 strain in cell culture. However, the role of NSP1 in RV infection

Book Review: Scorched Earth: Environmental Warfare As A Crime Against Humanity And Nature, Jeremy Ritzer

Genocide Studies and Prevention: An International Journal

The subtitle of Emmanuel Kreike’s Scorched Earth foreshadows the goal of this impressive and comprehensive contribution to the field. His goal is to chip away at the Nature-Culture dichotomy that he argues drives, and limits, much of the analysis that is produced of historical, and modern, warfare. Kreike uses the concept of environcide, which he defines as “intentionally or unintentionally damaging, destroying, or rendering inaccessible environmental infrastructure”, and argues that the traditional assumptions about nature and culture in the study of warfare obscure the importance of the natural world in determining who lives and who dies. For the field of …

Adipose-Specific Pparα Knockout Mice Have Increased Lipogenesis By Pask–Srebp1 Signaling And A Polarity Shift To Inflammatory Macrophages In White Adipose Tissue, Terry D. Hinds, Jr., Zachary A. Kipp, Mei Xu, Frederique B. Yiannikouris, Andrew J. Morris, Donald F. Stec, Walter Wahli, David E. Stec

Pharmacology and Nutritional Sciences Faculty Publications

The nuclear receptor PPARα is associated with reducing adiposity, especially in the liver, where it transactivates genes for β-oxidation. Contrarily, the function of PPARα in extrahepatic tissues is less known. Therefore, we established the first adipose-specific PPARα knockout (Ppara^FatKO) mice to determine the signaling position of PPARα in adipose tissue expansion that occurs during the development of obesity. To assess the function of PPARα in adiposity, female and male mice were placed on a high-fat diet (HFD) or normal chow for 30 weeks. Only the male Ppara^FatKO animals had significantly more adiposity in the inguinal white …

A Visually Realistic Simulator For Autonomous Evtol Aircraft, Seth M. Nielsen

Theses and Dissertations

Electrically powered vertical takeoff and landing (eVTOL) aircraft could provide a new mode of air transportation of people and cargo that is low-cost, on-demand, and able to reach more areas than is possible with current technology. They have the unique ability to takeoff and land in congested spaces yet efficiently travel long distances which makes them a promising technology for applications such as rapid medical assistance, automated package delivery, or human transportation. This type of aircraft has only recently become a possibility, owing to advancements in battery technology, computing power, and sensor technologies, and thus support for eVTOLs is lacking …

Colonial Necrocapitalism, State Secrecy, And The Palestinian Freedom Tunnel, Nadera Shalhoub-Kevorkian, Stephanie Wahab

School of Social Work Faculty Publications and Presentations

Secrecy and the use of “secret information” as capital in the hands of the state is mobilised by affective racialised machineries, cultivated on “security” grounds. Securitised secrecy is an assemblage of concealed operations juxtaposing various forms of invasions and dispossessions. It is a central strategy in the politico-economic life of the state to increase its scope of domination. Secrecy is used and abused to entrap and penetrate political subjects and entities. This article explores the necrocapitalist utilisation of secrecy embedded in the coloniser’s attempt to distort the mind of the colonised. Built from the voices of those affected by secrecy’s …

Arts & Literature: A Review Of The Poetry Book Unburied-Unmarked—The Untold Namibian Story Of The Genocide Of 1904–1908: Pieces And Pains Of The Struggle For Justice, Elise Pape

Genocide Studies and Prevention: An International Journal

Between 1904 and 1908, about eighty per cent of the Herero and fifty per cent of the Nama perished in what is today known as the first genocide of the twentieth century that took place in today’s Namibia under German colonial rule. Over decades, the German government has not officially recognized the genocide as such. Jephta U. Nguherimo is one of the descendants of survivors of this genocide and today lives in the United States. In his poetry book unBuried-unMarked–The unTold Namibian story of the Genocide of 1904-1908: Pieces and Pains of the Struggle for Justice that he has self-published …

Full Issue 15.3

Genocide Studies and Prevention: An International Journal

No abstract provided.

Collective Healing: Towards A Conceptual Framework, Garrett Thomson

Genocide Studies and Prevention: An International Journal

To understand what kind of collective healing practices might be most effective following mass atrocity, we need to comprehend better what counts as collective healing, and in what ways group healing processes differ from individual ones. We need clear and well-argued answers to these conceptual questions as a basis for deriving the criteria by which we might evaluate various practices in different contexts. Because means are valuable only in relation to ends, judging their effectiveness requires a definition of the ends in question and what is good about them. So, what counts as a good collective healing process? This conceptual …

Ongoing Genocides And The Need For Healing: The Cases Of Native And African Americans, Benjamin P. Bowser, Carl O. Word, Kate Shaw

Genocide Studies and Prevention: An International Journal

The elimination of Native peoples and the enslavement of Africans in the U.S. more than qualify as acts of historical state sponsored genocide. A feature of both genocides is that they ended as institutional practices but have continued culturally and psychologically. The primary contemporary legacy of these genocides is racism which reinforces historical trauma and grief. Suggestions are made for how healing for Native and African Americans can begin despite ongoing racism. This includes psychological counseling for White Americans with beliefs in White supremacy. Suggestions are also made for how reconciliation can begin at the county-level between descendants of slave …

Book Review: Are Perpetrators Under-Researched?, Christian Gudehus

Genocide Studies and Prevention: An International Journal

No abstract provided.

Police Use Of Social Media Technologies, Akpomudiare Darlynton Adegor

Theses and Dissertations

This study used a qualitative research design to analyze how the Little Rock Police Department (LRPD) utilizes social media technologies to promote its community policing philosophy. I conducted a content analysis on 586 tweets by LRPD and 992 public responses posted between May 2020 and May 2021. From my analysis, I found that LRPD social media platforms support both community policing and problem-solving. LRPD uses social media for interactions, connections, and partnerships with community members. The second notable finding was that the public is responsive and receptive to LRPD’s use of social media to connect with them. However, LRPD’s level …

Simulated Presence Use For Quality Of Life Maintenance And Reduction Of Symptoms Of Distress In Persons Living With Dementia In Long-Term Care, Erin E. Bush

Dissertations

Nursing home residents with dementia often have an array of neuropsychiatric symptoms, including dementia-related agitation. It is theorized that many of these agitation symptoms occur due to unmet psychosocial needs that could be met by the presence of a caring nursing staff member, family member, or friend.

The purpose of this study was to determine whether live simulated presence improves dementia-related agitation when offered, identify barriers and facilitators to simulated presence between caregivers and residents of long-term care during the COVID-19 pandemic, and to determine if live simulated presence by a caregiver delivered one-on-one improved quality of life in long-term …

Winter 2021

In The Loop

2021 Emmy Nominees; Animator Tapped by Cartoon Network; IndieCade Horizons 2021; Hack4Space; Security Daemons Prevail; Role Models: DePaul Originals Game Studio students build industry-level skills that benefit themselves and others; Frames and Fortune: Eugene Bush programmed his indie video studio with patience and planning; Reality Check: Heather Snyder Quinn augments reality to question systems of unchecked power

Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction In Nonhuman Primate Tb Granulomas, Bindu Singh, Dhiraj K Singh, Shashank R Ganatra, Ruby A Escobedo, Shabaana Khader, Larry S Schlesinger, Deepak Kaushal, Smriti Mehra

Open Access Publications

Myeloid-derived suppressor cells (MDSCs) represent an innate immune cell population comprised of immature myeloid cells and myeloid progenitors with very potent immunosuppressive potential. MDSCs are reported to be abundant in the lungs of active tuberculosis (TB) patients. We sought to perform an in-depth study of MDSCs during latent TB infection (LTBI) and active TB (ATB) using the nonhuman primate (NHP) model of pulmonary TB. We found a higher proportion of granulocytic, polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in the lungs of ATB animals compared to those with LTBI or naive control animals. Active disease in the lung, but not LTBI, was …

Ccr2 Signaling Restricts Sars-Cov-2 Infection, Abigail Vanderheiden, Jeronay Thomas, Allison L Soung, Meredith E Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A Cowan, Kathryn Pellegrini, Pei-Yong Shi, Arash Grakoui, Robyn S Klein, Steven E Bosinger, Jacob E Kohlmeier, Vineet D Menachery, Mehul S Suthar

Open Access Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a historic pandemic of respiratory disease (coronavirus disease 2019 [COVID-19]), and current evidence suggests that severe disease is associated with dysregulated immunity within the respiratory tract. However, the innate immune mechanisms that mediate protection during COVID-19 are not well defined. Here, we characterize a mouse model of SARS-CoV-2 infection and find that early CCR2 signaling restricts the viral burden in the lung. We find that a recently developed mouse-adapted SARS-CoV-2 (MA-SARS-CoV-2) strain as well as the emerging B.1.351 variant trigger an inflammatory response in the lung characterized by the expression of …

A Next Generation Sequencing-Based Protocol For Screening Of Variants Of Concern In Autism Spectrum Disorder, Jie Huang, Jun Liu, Ruiyi Tian, Kevin Liu, Patrick Zhuang, Hannah Tayla Sherman, Christoph Budjan, Michelle Fong, Min-Seo Jeong, Xue-Jun Kong

2020-Current year OA Pubs

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with strong genetic influences. There is an increasing demand for ASD genetic testing beyond the traditionally recommended microarray and syndromic autism testing; however, the current whole genome sequencing (WGS) and whole exome sequencing (WES) methods are lacking an academic standard for WGS variant annotation, reporting, and interpretation, tailored towards patients with ASD and offer very limited interpretation for clinical significance. Using WGS data from six family trios, we demonstrate the clinical feasibility and technical implementation of an evidence-based, fully transparent bioinformatics pipeline and report framework for an ASD-focused WGS genetic report. We …

Marker-Less Motion Capture System Using Openpose, Bin Feng

Electronic Theses and Dissertations Archive

Motion capture systems are widely used for measuring athletic performance and as a diagnostic tool in sports medicine. Standard motion capture systems record body movement using: (1) a set of cameras to localize body segments; or (2) specialized suits in which inertial measurement units are directly attached to body segments. Major drawbacks of these systems are limited portability, affordability, and accessibility. This contribution presents a markerless motion capture system using a commercially available sports camera and the OpenPose human pose estimation algorithm. We have validated the proposed markerless system by analyzing the human biometrics during running and jumping movements. The …

Information Seeking Behavior On Youtube's Recommendation System For Undergraduate Students In Surabaya Indonesia, Youngjoon Yang, Edi Dwi Riyanto, Imam Yuadi

Library Philosophy and Practice (e-journal)

YouTube is the most used social media platform in the world where users search for information through various search tools provided. This study aims to analyze the behavior of information-seeking on YouTube among undergraduate students in Surabaya, Indonesia. We examined their information-seeking behavior and its implementation in daily life. We also evaluated the information needs and interests. This research conducted online questionnaires that were sent to undergraduate students from 27 August 2021 to 6 September 2021 and received 143 responses. We then analyzed the data based on the response results and statistics from Google Forms. The results showed that they …

Questioning The Inclusivity Of Events: The Queer Perspective, Faith Ong, Clifford Lewis, Oscar Vorobjovas-Pinta

Research outputs 2014 to 2021

Event programmes are typically designed with a target audience in mind, and such design can inherently signal inclusion or exclusion of marginalised segments. This is particularly the case for lesbian, gay, bisexual, transgender, intersex and queer (LGBTIQ+) individuals, whose sexual and gender identities position them as an invisible minority on the periphery of society. Given the role of events in building community spirit, it is essential to ensure all members of a community feel able to participate in order to create a sense of belonging, fulfilling Sustainable Development Goals of inclusivity in community. Through the lens of Social Dominance Theory …

An Instructional Guide To Environmental Campaigns For K-12 Schools, Erin Mccarty

University Honors Theses

Evidence suggests environmental education can correlate with both short- and long-term behavioral changes, but existing research on the effectiveness of popular environmental education tactics show mixed results. Qualitative research was used in this study to assess student engagement and behavioral change within the context of environmental education campaigns. Ideally, students exposed to environmental campaigns become more informed on environmental issues and adjust their behavior to align with the campaign’s objectives. However, only a portion of environmental campaigns have these desired effects on their students. Based on a preliminary literature review, I anticipated the defining catalyst on post-campaign behavioral engagement would …

Sheep Performance In Italian Ryegrass Swards At Contrasting Sward Heights, Paulo C. De F. Carvalho, L. S. Pontes, E. O. Silveira, C. H. E. C. Poli, Carlos Nabinger, O. A. Pereira Neto, G. E. Maraschin

IGC Proceedings (1977-2023)

The objective of this study was to assess the effect of Italian ryegrass (Lolium multiflorum Lam.) sward height on lamb performance. The experiment was carried out at the Research Station of UFRGS, Eldorado do Sul, Brazil. Yearling no-castrated male lambs were assessed in terms of individual animal performance and gain per hectare. The experiment was carried out in a randomised block design with three replications of four treatments: 5, 10, 15 and 20 cm of sward surface height (SSH), which were maintained using continuous variable stocking, and monitored by a sward stick. Samples of 0.25 m² were cut …

Animal Performance In Pastures Of Panicum Maximum Cv. Ipr 86 Fertilized With Nitrogen, S. M. B. Lugão, L. R. De A. Rodrigues, E. B. Malheiros, J. J. Dos S. Abrahão, A. De Morais

IGC Proceedings (1977-2023)

The experiment was carried out at the Experimental Station of the IAPAR in Paranavaí– PR, Brazil, from October 1998 to May 1999 to evaluate the response of crossbred steers grazing pastures of Panicum maximum cv. IPR 86 fertilized with four doses of N (0; 150; 300 and 450 kg.ha^-1.year). The grass was grazed according to a rotational grazing system with grazing cycles (GCs) of 40 days (grazing period of 5 days and rest period of 35 days). It was used a randomized complete block design, with split-plots, and two replications per treatment, being the N-doses studied in the …

Dairy Cow Performance On Pasture-Based Feeding Systems And In Confinement, Renato S. Fontaneli, Lynn E. Sollenberger, C. R. Staples

IGC Proceedings (1977-2023)

Interest in grazing systems is growing among farmers in the USA as a means of reducing feed costs for lactating dairy cows. An experiment was conducted near Gainesville, FL to compare milk production and composition and milk income minus feed costs from two pasture-based systems with those of a conventional confinement housing system over a 276-d period. System 1 was based on a mixture of rye (Secale cereale L.), annual ryegrass (Lolium multiflorum Lam.), crimson clover (Trifolium incarnatum L.), and red clover (Trifolium pratense L.) during the winter-spring seasons and pearl millet (Pennisetum glaucum [L.] …

News, Announcements, And Remembrances

Liberty Theological Review

News from various organizations in related disciplines. Announcements from Eleutheria editors about internal matters. Remembrances of people and events that include in memoriams, retirements, interesting lookbacks, etc.