Digital Commons Network^™

Effects Of Walnut Paste On Kidney-Yang Deficiency Mice And Their Gut Microbiota, Wang Liping, Zhao Shenglan, Yang Rui, Chen Yanling, Wang Xiaoyan

Food and Machinery

[Objective] To investigate the effects of walnut paste on kidney-yang deficiency and the gut microbiota. [Methods] Using hydrocortisone [25 mg/(kg·d)] to establish a kidney-yang deficiency mouse model, the experiment is randomly divided into a normal group, a model group, a positive control group, and low-, medium-, and high-dose walnut paste groups. The mice are continuously administered walnut paste via gavage for 14 days. Changes in body weight, autonomous activity, and organ indices are analyzed. Serum levels of cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP), corticosterone (CORT), testosterone (T), and estradiol (E2) are measured. Pathological conditions of the kidney, testis, …

Mixing Design And Quality Optimization Of High-Moisture Textured Vegetable Protein, Fan Jiong, Xu Yuanfang, Du Tongshen, Yan Jingxin, Zhang Huien, Chao Shaoqian, Yang Hua

Food and Machinery

[Objective] To optimize the overall quality of high-moisture textured vegetable protein products. [Methods] The addition levels of soybean protein isolate, pea protein, wheat protein, and flour were used as experimental factors, with hardness and sensory evaluation as response indices. A D-optimal mixture design was applied to optimize the plant-based raw material formulation. Based on the optimal formulation, the effects of twin-screw extrusion mechanical parameters on the protein textural characteristics of high-moisture textured vegetable protein were further investigated. [Results] The optimal mixture formulation consisted of 59% soybean protein isolate, 30% pea protein, 5% wheat protein, and 6% flour (based on powder …

Research Progress On The Molecular Mechanisms And Structure-Activity Relationships Of Morchella Esculenta Polysaccharides In Immune Regulation, Zhou Yangjie, Ming Jian, Rao Zhenan, He Ying, Lei Xiaojuan, Zhao Jichun

Food and Machinery

Morchella esculenta is a precious edible and medicinal fungus,rich in active substances such as polyphenols,polypeptides and polysaccharides. M.esculenta polysaccharides (MEP) are a class of carbohydrates formed by the polymerization of aldose or ketose through glycosidic bonds,exhibiting a variety of biological activities including immune regulation,hypolipidemic effects,and anti-fatigue properties. With the deepening of research,the market demand for MEP is constantly increasing,making it particularly important to optimize its extraction and purification processes. Immune regulation is a key process in living organisms,and as the main active ingredient,MEP has attracted significant attention for its immunoregulatory function. However,its specific mechanism of action and structure-activity relationships remain …

Research Progress On Immunomodulatory Effect Of Food-Derived Bioactive Peptides, Zhao Xinglu, Yang Xiongchao, Wang Yidan, Zhao Shenglan, Ma Yage

Food and Machinery

Immune system imbalance arises from a complex interplay of genetic,environmental,chronic disease, age, and emotional factors. It can lead to diseases including diabetes, obesity, atherosclerosis, and cancer, representing a critical threat to human health. Food-derived bioactive peptides possess immunomodulatory properties. As safe food resources, they are characterized by multi-targeting and high consumer acceptability. This review primarily focuses on the preparation technologies, structural analysis, structure-activity relationships, and mechanisms of bioactive peptides derived from food sources. Furthermore, current achievements are summarized in the field of immunomodulation by the peptides, while perspectives are offered.

Feeding Performance And Survival Of Louisiana Poeciliid Fishes Exposed To Residential Wastewater Effluent, Jonathan Chapman

Masters Theses

Mosquitoes are a primary transmitter of vector-borne disease, and their larvae can thrive within shallow pools of stagnant water. Rainwater drainage ditches are a common sight in many communities, and in Louisiana, they are dually used as outlets for onsite residential wastewater discharge in neighborhoods disassociated from municipal sewage treatment. However, when discharge systems malfunction, the water becomes uninhabitable to mosquito predators, allowing mosquitoes to thrive. This research examines the predation performance of mosquitofish (Gambusia affinis), sailfin mollies (Poecilia latipinna), and least killifish (Heterandria formosa), the primary biological control agents utilized to combat mosquitoes within ditch communities. Individuals were captured …

The Role Of Isotocin In Female Zebrafish (Danio Rerio) Reproductive Behavior And Its Implication For Intranasal Oxytocin Therapy In Humans, Katelynn M. Benge

Masters Theses

In the past several decades, oxytocin has been colloquially termed the “cuddle hormone,” due to its role in pair-bonding and monogamy (Carter et al., 1992). In addition to being used experimentally for psychological disorder, it has also been used in couple’s counseling settings (Anagnostou et al., 2014; Domes et al., 2016). The outcomes of this research reveal mixed results, creating a need for further research in the topic to understand the exact mechanisms by which oxytocin works in the brain to induce this prosocial response. This study sought to address this deficit through the zebrafish animal model. The zebrafish serves …

Faculty, Staff, And Counselor Awareness Of The Challenges Faced By Autistic Students: A Quantitative Descriptive Study Of Resources, Training, And Support For Autistic Student Success In Higher Education, Erika Rosario

Doctoral Dissertations

Higher education institutions should establish two essential measures to support students with autism spectrum disorder (ASD): they need to implement standardized training for all personnel working on campus and create opportunities for hands-on experience through peer programs and collaborative educational events. The pursuit of equity in education demands nothing less. This study investigates the extent to which university faculty, staff, and counselors are aware of the challenges faced by autistic students, how knowledgeable they are about resources available to aid them, and the degree of their training, support, and collaboration in addressing students’ needs. By answering these research questions, the …

The Food Ethics, Sustainability And Alternatives Course: A Mixed Assessment Of University Students’ Readiness For Change, Charles Feldman, Stephanie A. Navarro Silvera

Department of Nutrition and Food Studies Scholarship and Creative Works

Growing interest in food sustainability education aims to increase awareness of food distribution systems, environmental degradation, and the connectivity of sustainable and ethical food practices. However, recent scholarship has questioned whether such pedagogical efforts are meaningfully internalized by students or lead to sustained behavioral change. Prior studies document persistent gaps in students’ understanding of sustainability impacts and the limited effectiveness of existing instructional approaches in promoting transformative engagement. To address these concerns, the Food Ethics, Sustainability and Alternatives (FESA) course was implemented with 21 undergraduate and graduate students at Montclair State University (Montclair, NJ, USA). Course outcomes were evaluated using …

Regeneration Of Swimming Antennae After Partial Amputation In Long- And Short-Lived Daphnia, Charles Schumpert, Rekha C. Patel, Jeffry L. Dudycha

Faculty Publications

Regeneration, the ability of an animal to restart a developmental process and thus rebuild itself following injury or loss, is generally thought to be inversely related to aging, the progressive decline of organismal functions and fitness that occurs as adults get older. We sought to test whether recently evolved differences of aging in the crustacean Daphnia were accompanied by evolutionary divergence of regenerative ability. Using the short-lived D. pulex and the long-lived D. pulicaria, we conducted an assessment of regenerative ability in which we amputated part of the swimming antenna and observed subsequent regeneration. In four clones isolated from …

Understanding Higher-Order Motion Terms In Image Sequences, Fisseha Admasu Ferede

Electronic Theses and Dissertations Archive

This dissertation presents a comprehensive framework for learning accurate, and physically meaningful representation of motion from image sequences. The central theme of this work lies in advancing optical flow estimation from discrete-time two-frame formulation toward a continuous time multi-frame model capable of learning higher-order motion terms and dynamics, with wide ranging applications including developing structural disease biomarkers from medical images. We first develop SSTM (Spatiotemporal Recurrent Transformer for Multi-Frame Optical Flow Estimation), a deep learning model that leverages a sequence of multi-frames to infer accurate optical flow by learning temporal dependencies across successive motion cues. The architecture integrates recurrent 3D …

University Joins National Network Empowering Leaders In The Catholic Church, University Of Dayton

News Releases

The University of Dayton is joining a network of 16 Catholic colleges and universities, funded by a $10 million grant, to strengthen "synodality" in the U.S. Catholic Church, or the way the Church engages in listening, dialogue and decision-making.

Insights On Global Rangeland Ecosystem Services Shaped By Grazing And Fertilization, Laura Yahdjian, Sofía Campana, Pedro M. Tognetti, Juan Alberti, Pamela Graff, Cecilia Molina, Elizabeth T. Borer, Eric W. Seabloom, Suzanne M. Prober, Andrew S. Macdougall, Anita C. Risch, Jodi N. Price, Sally A. Power, Isabel C. Barrio, Erika Hersch-Green, Philip A. Fay, Sumanta Bagchi, Jonathan D. Bakker, Dana Blumenthal, Elizabeth H. Boughton, Cynthia S. Brown, Miguel N. Bugalho, Marc Cadotte, Maria C. Caldeira, Jane A. Catford, Clinton Carbutt, Qingqing Chen, Scott L. Collins, Thomas W. Crowther, Carla D’Antonio, Christopher R. Dickman

Michigan Tech Publications

Rangelands are crucial to human well-being, but their ability to provide ecosystem services is threatened. We (1) quantified key ecosystem services provided by rangelands, (2) assessed short- and long-term impacts of fertilization (nutrient addition) and the exclusion of large grazing herbivores with fences (herbivore exclusion) on services, and (3) identified synergies and trade-offs among services. We measured indicators of ecosystem services and plant diversity at 79 sites across six continents in the global Nutrient Network. Short-term herbivore exclusion increased forage quantity and soil fertility, but longer-term herbivore exclusion decreased both along with plant richness and pollination. Nutrient addition improved forage …

Ai-Assisted Tailored Intervention For Nurse Burnout: A Three-Group Randomized Controlled Trial, Gumhee Baek, Chiyoung Cha

Individual Articles

Background: High-stress environments, heavy workloads, and the emotional demands of patient care, which are common challenges faced by nurses, are factors that can lead to burnout. Shift work can make traditional burnout interventions costly and difficult to implement. Artificial intelligence (AI) could offer solutions that are less constrained by time, resources, and labor.

Aim: To investigate the effectiveness of an AI-assisted intervention in reducing nurse burnout.

Methods: A single-blind, three-group, randomized controlled trial of 120 nurses (40 per group) was conducted from June 2023 to July 2023. The AI-assisted tailored intervention included two 2-week programs, delivering one of four programs …

Decoupling Of Reproduction And Lifespan Trade-Off In Caenorhabditis Elegans Through Microbial Programming, Nora M. Villafuerte

LSU Master's Theses

The microbiome is increasingly recognized as a major regulator of host physiology. Using the Caenorhabditis elegans model, we investigated how natural commensal bacteria modulate host reproduction and lifespan through internal egg hatching, a phenotype in which retained embryos hatch within the maternal body. Screening strains from the CeMbio collection identified four focal strains Ochrobactrum BH3, Lelliottia JUb66, Pantoea BIGb0393, and Enterobacter CEent1 that significantly increased internal egg hatching during the late reproductive period. This contrasts with pathogenic bacteria, which induce early-onset internal egg hatching. Across the focal strains, worms exhibited reduced total brood size but an expanded reproductive window relative …

Induction Of Moderate Dna Damage Enhances Megakaryopoiesis And Platelet Production, Virginia Camacho, Luis Francisco Zirnberger Batista, Et Al.

2020-Current year OA Pubs

Megakaryocytes (MKs) are large, hematopoietic cells with a polyploid, multilobulated nucleus. Although DNA replication in MKs (endomitosis) is well studied, limited investigations have examined the impact of DNA instability on megakaryopoiesis. Poly-adenosine diphosphate (ADP) ribose polymerase (PARP) inhibitors are chemotherapeutics that result in accumulation of DNA damage and are commonly associated with thrombocytopenia, presumably mediated through platelet progenitors, MKs. To explore PARP inhibitor-induced thrombocytopenia, we treated mice with the PARP inhibitor niraparib. Although high-dose niraparib treatment led to thrombocytopenia, consistent with clinical observations, lower-dose treatment led to a significant increase in bone marrow MKs, MK progenitors (MkPs), and circulating platelets. …

Differential Virulence And Immune Recognition Of Klebsiella Pneumoniae O-Antigen Subtypes O2Α And O2Β, Paeton L Wantuch, Lloyd S Robinson, Cory J Knoot, Christian M Harding, David A Rosen

2020-Current year OA Pubs

No abstract provided.

A Chemogenetic Approach For Temporal And Cell-Specific Activation Of Endogenous Gpcrs In Vivo, Gwendolyn Shingles, Qianqian Pang, Jian Weng, Ryan Singer, Waleed Babar, Jiaqi Shen, Luis Vazquez-Rivera, Yao Chen, Peng Li, Wenjing Wang

2020-Current year OA Pubs

Cell-specific regulation of endogenous G protein-coupled receptors (GPCRs) is crucial for understanding their roles in physiological processes. We present chemogenetic tools using shield-1-dependent irreversible protein switches to regulate peptide agonist activity. To demonstrate this platform, we engineered chemogenetically regulated pituitary adenylate cyclase activating polypeptide (cPACAP), which exhibited >15-fold chemical-dependent regulation of endogenous receptor activity. In vivo application of cPACAP allowed neuronal activation via the endogenous receptor for PACAP, engaging neural circuits that control respiratory and feeding behaviors. By integrating cPACAP with transgenic mice, we selectively activated endogenous PACAP receptor signaling in hypocretin-expressing neurons of the lateral hypothalamic area (LHA), revealing …

Academic Senate - Agenda, 01/13/2026, Academic Senate

Academic Senate Agendas

No abstract provided.

The Coalition For Fairness In Soho And Noho, Inc. V. City Of New York

All Decisions

The Court of Appeals reversed the Appellate Division, upholding the City's 2021 rezoning plan for SoHo/NoHo artist lofts. The plan imposed a one-time fee on landlords for converting Joint Living-Work Quarters for Artists (JLWQA) units to unrestricted residential use. The court held that this fee does not constitute a compensable taking under the Fifth Amendment's Takings Clause. It reasoned that landlords lack a compensable property interest in converting their units to a new, more valuable use, as the fee does not burden their existing property rights or coerce them into relinquishing an interest that the government would otherwise have to …

The Corpus Juris Of (Alaska Native) Inherent Tribal Sovereignty, Nazune Menka

Alaska Law Review

The inherent Tribal sovereignty of Native nations predates the formation of the United States and is reflected in the constitutional vision of tripartite sovereignty. Yet their sovereignty is oft diminished explicitly by federal law or implicitly by federal courts. This implicit divestiture is often the result of the federal judiciary’s inconsistent interpretations of Indigenous Peoples law. This Article argues that a more principled and coherent approach for federal judges would be to consistently make use of the corpus juris, or whole body of law, including the in pari materia or affiliated statutes canon. The Article posits that the corpus juris …

Anchoring Deference: The Chevron Doctrine, Loper Bright, And Alaska Administrative Law, Jon W. Katchen, Will R. Crowther

Alaska Law Review

After statehood, the Alaska Supreme Court operated on a blank legal slate. No Alaska precedent, for example, addressed the fundamental question of when courts should defer to an agency’s statutory interpretation. In addressing this issue, the Alaska Supreme Court largely adopted the framework developed by federal courts in the 1950s and 1960s, prior to the emergence of the Chevron doctrine. The federal case law from this era relied on nebulous standards to guide when an agency’s interpretations were subject to the deferential reasonable basis review. Not surprisingly, by adopting that federal jurisprudence, Alaska precedent suffers from the same shortcomings. And …

Alaska’S Hidden Gems: Advocating For The Protection Of Deep-Sea Corals, Both In The Courtroom And Beyond, Lauren Beizer

Alaska Law Review

Coral reefs are ecologically, financially, and aesthetically one of the world’s greatest resources. Off the coast of Alaska, many unique species of deep-sea cold-water corals exist and provide various public health benefits, contribute vital ecosystem functions to their surrounding environment, and serve as economic tourist attractions. Alaska’s coral reefs are exceedingly valuable to the Earth due to their overall ecological value. However, these unique coral species significantly lack state and federal protections, which have recently been under consideration in several lawsuits at the federal level. American Oceans Campaign v. Daley and Oceana, Inc. v. National Marine Fisheries Service et al., …

Sullivan County Advisory Council January 2026 Meeting Minutes, Extension

Advisory Council

No abstract provided.

Investigating Host Factors In Coronavirus Assembly And Egress, Surovi Binte Sharmin Mohona

Dissertations

Coronavirus (CoV) structural proteins congregate at the ER-Golgi intermediate compartments (ERGIC) prior to virus budding into the organelle lumen. Subsequent trafficking and fusion of virus-containing, ERGIC-derived vesicles then release nascent viruses from infected cells. Our findings in this dissertation illuminate mechanisms by which CoV structural proteins coalesce at the virus assembly and budding sites. The cytoplasmic tails of all CoV spike (S) glycoproteins contain variants of a consensus KxKxx coatomer-binding motif. Host coatomer complexes facilitate retrograde trafficking of client cargo proteins via recognition of such motifs. Utilizing reverse genetics methodologies, we introduced variations in the S coatomer motif in a …

Direct Effects Of Capsaicin On Voltage-Dependent Calcium Channels Of Mammalian Skeletal Muscle, Dmytro Isaev, Tatiana Prytkova, Badarunnisa Mohamed, Mohamed Omar Mahgoub, Keun Hang Susan Yang, Murat Oz

All Works

Capsaicin, a naturally occurring polyphenol, is known to affect energy expenditure and muscle fatigue and modulate contractions in skeletal muscle. The L-type Ca²⁺ channels are known to be an important ion channel involved in the various muscle functions and the effect of capsaicin on the skeletal L-type Ca²⁺ channels is currently unknown. In this study, the effects of capsaicin and capsaicin analogs on depolarization-induced Ca²⁺ effluxes through L-type Ca²⁺ channels in transverse tubule membranes from rabbit skeletal muscle and L-type Ca²⁺ currents recorded using the whole-cell patch clamp technique in rat myotubes were examined. Capsaicin, …

Can I Freeze-Dry That? A Practical Guide To Safe And Effective Freeze-Drying, Victoria Carlile, Morgan Wayment, Jose Brandao

All Current Publications

Freeze-drying can preserve most everyday foods, but not all foods work well. Whether you are preparing for a long trip or are interested in long-term storage, it is important to know which food can be freeze-dried safely and which ones should not be attempted. This knowledge helps ensure food safety, quality, and success. This fact sheet provides information on how freeze-drying works, the risks involved, and which foods can be more challenging to freeze-dry.

Confluence, Vol. 4, Iss. 2, Full Issue

The Confluence

No abstract provided.

Lucy Wortham James And The Gospel Of Wealth: A Case Study Of Female Philanthropy In Rural Missouri During The Progressive Era, Jacob F. Rinehart

The Confluence

Various historical scholars have examined the role of Andrew Carnegie's Gospel of Wealth on philanthropic attitudes and endeavors of affluent Americans during the Progressive Era. Modern developments, driven by post-structural feminist theory, have shown that rural-born Missouri women, exemplified by Phoebe Apperson Hearst, acted as complementary equals to Carnegie through their humanitarian efforts by uniquely interpreting and implementing his social doctrines. However, the existing scholarship has focused substantially on coastal developments, neglecting the role of this benevolence in rural Missouri communities. By examining the philanthropic endeavors of Lucy Wortham James, both during her life and post-mortem through her endowment of …

Land Use Zoning: The Answer To Housing Affordability? A Look At Aukland, New Zealand And Minneapolis, Minnesota, Charlsey Kelly

Georgia Journal of International & Comparative Law

For many individuals, purchasing their first home is a monumental step which they look forward to for years. Homes are one of the most valuable assets individuals purchase within their lifetime. In the current housing market, reaching this milestone is becoming more and more difficult for individuals. Adequate and affordable housing is scarce. This is not just an issue plaguing the United States, but it is an issue many metro areas worldwide currently face.

Cultivating Global Citizenship At Home: A Content Analysis Of Collaborative Online International Learning (Coil), Allison Freed, Evan W. Faidley, Valerie G. Couture, K. Adele Okoli, Leticia De La Garza, Adriian Gardner, Crystal Harris, Leah Horton, Brittany N. Saviers, Sunjung Kim Thao, Amber Wilson

International Journal of Transformative Teaching and Learning in Higher Education

This study presents a content analysis of scholarly works on collaborative online international learning (COIL) published between 2015 and 2023. Conducted by an interdisciplinary faculty group, the research explores how COIL literature frames student learning outcomes within internationalization-at-home efforts. Findings reveal that COIL most frequently supports assignments/projects, as well as intercultural communication and global competence, particularly at the undergraduate level. The analysis highlights COIL’s potential to democratize global learning by addressing access barriers for both students and faculty. The study calls for expanded research on the long-term impacts of COIL, inclusive pedagogies, and cross-institutional collaborations to advance global citizenship in …