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Understanding The Effects Of Ligand Environment On Important Properties Of Redox-Active Europium Using Computational Chemistry And T1-Weighted Magnetic Resonance Imaging, Brooke Anne Corbin

Wayne State University Dissertations

This thesis is a collection of seven chapters that describes a combination of literature research and experimental analyses into the study of inorganic complexes, with an emphasis on the photophysics and coordination of redox-active europium. The first chapter summarizes the key features of each chapter. The second and third chapters are detailed overviews, including historical context, current studies, and future goals of imaging science, with an emphasis on inorganic complexes. The fourth chapter describes the design of a screening procedure to study new ligand environments for redox-active europium using magnetic resonance imaging and a proof-of-concept experiment. The fifth chapter is …

Role Of Aldehyde Dehydrogenase 2 (Aldh2) In The Decrease In Coronary Angiogenesis In Type 2 Diabetes Mellitus: Identifying Novel Signaling Pathways, Bipradas Roy

Wayne State University Dissertations

Coronary endothelial cell (CECs) damage and rarefaction of coronary microvasculature are implicated in diabetes-induced heart failure with preserved ejection fraction (HFpEF). 4-hydroxy-2-nonenal (4-HNE), a reactive aldehyde that is increased in diabetic hearts, contributes to CEC dysfunction and cardiotoxicity. Aldehyde dehydrogenase (ALDH) 2, a mitochondrial enzyme that detoxifies 4-HNE and confers cardioprotection. However, ALDH2 activity is decreased in diabetic hearts, which results in the augmentation of 4HNE-induced cardiotoxicity. Thus, we hypothesize that activation of ALDH2 in CECs reduces 4-HNE-mediated cell signaling aberrations and preserves coronary angiogenesis. We employed cell culture studies and animal models to test our hypothesis. In our cell …

Small G- Protein Regulators Of Islet Beta Cell Function, Suhadinie Sameera Gamage

Wayne State University Dissertations

Defects in insulin secretion from pancreatic islet beta- cells leads to long term complications such as type 2 diabetes mellitus. The mechanism and regulation of glucose stimulated insulin secretion (GSIS) as well as factors contributing to pancreatic islet beta-cell demise are yet poorly understood. Previous work from our laboratory demonstrated that Ras-related C3 botulinum toxin substrate 1 (Rac1), a small G- protein is involved in GSIS as well as in culminating dysfunction under metabolic stress. Cycling of Rac1 between its inactive and active form is considered a vital event in glucose stimulated insulin secretion. This conversion is made possible by …

Cannabis, Consumers, And The Trademark Laundering Trap, Viva R. Moffat, Sam Kamin, Timothy Maffett

Sturm College of Law: Faculty Scholarship

At the moment, cannabis companies cannot get trademark protection for their marijuana and marijuana-related products because the “lawful use” doctrine limits federal trademark protection to goods lawfully sold in commerce. Given that the drug remains illegal under federal law, this may not sound like much of a problem, but it has serious consequences for consumers of marijuana. Without trademark rights, a cannabis company in one state can simply use the brand name of a prominent company in another state and consumers will assume that they are getting the products they have come to rely on, with potentially dangerous results. As …

Inscape 2022, Morehead State University.

Inscape: Art & Literary Magazine Archive

The 2022 edition of the Inscape: Literary and Art Magazine.

South Dakota State University Undergraduate Catalog 2022-2023, South Dakota State University

South Dakota State University Catalogs and Bulletins: 1935 to present

No abstract provided.

Using The Protection Motivation Theory To Understand The Mental Health Impact Of Surviving Covid-19, Kaprea Johnson, Angel Spence, Yousef Sherif, Dana Brookover, Adrienne White

Adultspan Journal

Due to the widespread effects of COVID-19, mental health professionals need to understand the lived experiences of survivors. Data were collected from YouTube videos (N = 52), which contained firsthand perspectives from COVID-19 survivors. Survivors understood the high stakes of COVID-19, reported the dual threat to physical and mental health, entered “survival mode,” and had both positive and negative reflections on the experience. Implications for mental health professionals and future research directions are included.

Psychedelic Therapies At The Crossroads Of Trauma And Substance Use: Historical Perspectives And Future Directions, Taking A Lead From New Mexico, Snehal R. Bhatt, Maya Armstrong, Tassy Parker, Marcello Maviglia, Rebecca Kass, Lawrence Leeman, Paul Romo, Douglas Ziedonis

Family and Community Medicine Research and Scholarship

Post-traumatic stress disorder (PTSD), a common condition with potentially devastating individual, family, and societal consequences, is highly associated with substance use disorders (SUDs). The association between PTSD and SUD is complex and may involve adverse childhood experiences (ACEs), historical and multi-generational traumas, and social determinants of health as well as cultural and spiritual contexts. Current psychosocial and pharmacological treatments for PTSD are only modestly effective, and there is a need for more research on therapeutic interventions for co-occurring PTSD and SUD, including whether to provide integrated or sequential treatments. There is a current resurgence of interest in psychedelics as potential …

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2022, Michael Haederle, Sara Mota, El Webb, Chris Corrie, Byron Hughey-Geer, Jett Loe, Sarah Head, Elizabeth Sandlin

Research Annual Reports

No abstract provided.

Developing A New Treatment For Superficial Fungal Infection Using Antifungal Collagen-Hsaf Dressing, Jing Zhong, Xiayi Yan, Xin Zuo, Xuan Zhao, Jiahui Yang, Qin Dou, Lulu Peng, Yuxiang Zhu, Yichen Xiao, Zeran Bian, Dalian He, Qiushuang Xu, Stephen Wright, Yaoyao Li, Liangcheng Du, Yan Wang, Jin Yuan

Department of Chemistry: Faculty Publications

Fungal pathogens are common causes of superficial clinical infection. Their increasing drug resistance gradually makes existing antifungal drugs ineffective. Heat stable antifungal factor (HSAF) is a novel antifungal natural product with a unique structure. However, the application of HSAF has been hampered by very low yield in the current microbial producers and from extremely poor solubility in water and common solvents. In this study, we developed an effective mode of treatment applying HSAF to superficial fungal infections. The marine-derived Lysobacter enzymogenes YC36 contains the HSAF biosynthetic gene cluster, which we activated by the interspecific signaling molecule indole. An efficient extraction …

Ecological Risk Assessment For The Western Rock Lobster Resource : Workshop Procedure And Outcomes, R Stoklosa

Fisheries Occasional Publications

No abstract provided.

Drones In Agriculture, Jason P. De Koff, Priya Saini

Extension Publications

No abstract provided.

Black Fly Survey Of A Whooping Crane Reintroduction Area In Eastern Wisconsin, Richard P. Urbanek, Peter H. Adler

Proceedings of the North American Crane Workshop

Nest desertion due to harassment by black flies (Simulium annulus and S. johannseni) during incubation has been a major factor inhibiting success of the reintroduced Eastern Migratory Population of whooping cranes (Grus americana). To avoid this problem, which was prevalent in the core reintroduction area in central Wisconsin, the Whooping Crane Eastern Partnership changed the primary reintroduction area to eastern Wisconsin in 2011. However, a 2010 assessment of black flies in that area had concentrated predominantly on the southern portion of the new area. In 2017-2018, we collected the first samples of black flies in …

Does The Affirmative Consent Standard Increase The Accuracy Of Sexual Assault Perceptions? It Depends On How You Learn About The Standard, Abigail R. Riemer, Kathryn Holland, Evan Mccracken, Amanda Dale, Sarah Gervais

Department of Psychology: Faculty Publications

Objective: Colleges and universities are increasingly adopting affirmative consent standards of sexual assault, in which consent is defined as conscious and voluntary “yeses” given throughout a sexual interaction. We examined the impact of affirmative consent standards on perceptions of assault and consent.

Hypotheses: We hypothesized that in sexual assault scenarios involving physical force or verbal coercion, exposure to the consent standard would increase perceptions of assault and decrease perceptions of consent relative to not being exposed to the standard. We then explored whether dehumanization of the perpetrator or the victim mediates the association between assault type and sexual assault perceptions …

Justice Breyer: No Friend To Ip Law, 21 Uic Rev. Intell. Prop. L. 58 (2022), Kevin Noonan

UIC Review of Intellectual Property Law

No abstract provided.

Van Buren V. United States: An Employer Defeat Or Hacker’S Victory – Or Something In Between, 21 Uic Rev. Intell. Prop. L. 166 (2022), Melanie Assad

UIC Review of Intellectual Property Law

No abstract provided.

No Panacea Attractant For Wild Pigs (Sus Scrofa), But Season And Location Matter, Nathan P. Snow, Caitlin A. Kupferman, Michael J. Lavelle, Kim M. Pepin, Madeline H. Melton, Whitney J. Gann, Kurt C. Vercauteren, James C. Beasley

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) are a prolific invasive species throughout many regions of the world that cause extensive economic and environmental damage. Trapping is a common strategy for reducing their populations with baits (i.e., food) and attractants (e.g., scents) used to lure wild pigs into traps. However, there is little information on which scent attractants may attract wild pigs more readily and rapidly across regions and seasons. We examined 60 scent attractants for wild pigs that could be used to increase trapping success across three seasons (winter, spring, and fall) and in two geographic regions, including a warm …

Predation Thresholds For Reintroduction Of Native Avifauna Following Suppression Of Invasive Brown Treesnakes On Guam, Robert M. Mcelderry, Eben H. Paxton, Andre V. Nguyen, Shane R. Siers

United States Department of Agriculture Wildlife Services: Staff Publications

The brown treesnake (BTS) (Boiga irregularis) invasion on Guåhan (in English, Guam) led to the extirpation of nearly all native forest birds. In recent years, methods have been developed to reduce BTS abundance on a landscape scale. To help assess the prospects for the successful reintroduction of native birds to Guåhan following BTS suppression, we modeled bird population persistence based on their life history characteristics and relative sensitivity to BTS predation. We constructed individual-based models and simulated BTS predation in hypothetical founding populations for each of seven candidate bird species. We represented BTS predation risk in two steps: …

Conserving Endangered Black-Footed Ferrets: Biological Threats, Political Challenges, And Lessons Learned, Travis M. Livieri, Steven C. Forrest, Marc R. Matchett, Stewart Breck

United States Department of Agriculture Wildlife Services: Staff Publications

There may be few stories in the annals of wildlife management that are as dramatic as the near demise and comeback of the black-footed ferret (Mustela nigripes). Endemic only to North America, this charming little carnivore found only in the continent’s central grasslands was hardly known to science until the mid-20th century. By then, vast colonies of the prey it depended on for food and shelter, the prairie dog (Cynomys spp.), had been wiped out through disease (sylvatic plague) and an agricultural industry with little tolerance for burrowing and grazing rodents. At its low point, the species’ …

Viii. Hieronymus’ Bench: Conversations Dürer Heaney, Auerbach Panofsky, Heidegger Heraclitus, Hölderlin Rilke, Charles S. Taylor

Wine Journey: Tasting Dwelling Learning at The Kitchen Table

The names in this essay’s sub-title sketch its outline. An image by Albrecht Dürer and a poem by Seamus Heaney, essays by Eric Auerbach and Erwin Panofsky are new inclusions into a rambling immersion into Heraclitus Heidegger Rilke and Hölderlin. The resulting octet gives major solo roles to the new contributors while at the same time deepening the wonder at the questions arising. The first seven chapters and the late-added overture were each written as stand-alone works and had breaks of time separating them. This new essay began before Learning to Taste (Ch. 7) was completed. While completing Learning to …

Blood Sisters, Anastacia Puertas

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Mapping The Margins: Intersecting Disability Justice And Design Practices For Transformative Architectural Praxis, Julia Chou

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Let's Dance Together!, Tillie Morrisette

Renée Crown University Honors Thesis Projects - All

No abstract provided.

A Unified Theory Of Musical Meaning, Luis Verdin

CMC Senior Theses

In this thesis, I present a novel theory of musical meaning. This theory posits a complementary relationship between the theories described in Lerdahl and Jackendoff’s Generative Theory of Tonal Music and Arnie Cox’s Music and Embodied Cognition. Each of these theories explain particular aspects of musical meaning (semantic and grammatical, respectively), though I argue that by unifying these theories into a broader framework, they can explain more about musical meaning than they could individually. This unification is performed via the novel theory I present: the Analogical Argument. This argument suggests that Lerdahl and Jackendoff’s Generative Theory of Tonal Music is …

The Key Deer Is Headed For Extinction: How Repealing A Trump-Era Federal Rule Defining "Habitat" Could Allow Assisted Migration To Save Species Threatened By Climate Change, Kennedi Fichtel

St. Thomas Law Review

Climate change induced sea level rise is imminent. In fact, the U.S. Army Corps of Engineers has predicted that “[b]y 2045, the sea level in the Florida Keys will rise 15 inches . . . .” Such a projection usually invites questions about the implications for coastal residential homeowners. However, this projection means so much more for the voiceless inhabitants of the Florida Keys. Anthropogenic climate change that leads to sea level rise of this magnitude will be responsible for permanently destroying species’ habitats, and therefore impacting their ability to survive. For endangered and threatened species, this means extinction. As …

U.S. Drug Reform: A Cultural Shift, Leionah J. Noah

St. Thomas Law Review

When a human body ingests a lethal dose of heroin, the body goes through an enormous physiological transformation. The functions of the central nervous system begin to depress, breathing is shallowed, the pulse is weakened, and the skin turns blue or gray with dark lips and fingernails. An alert person must quickly administer naloxone, an opioid antagonist, to reverse the effects of a heroin overdose, as symptoms typically begin after ten minutes. For many, however, their lives end with an overdose, despite this outcome being preventable. This paper will establish that drug overdose deaths are preventable for an entirely different …

Spatial Variability Of Silver Carp Population Demographics In A Large Tributary River, J. P. Werner, Q. J. Dean, Mark A. Pegg, M. J. Hamel

School of Natural Resources: Faculty Publications

No abstract provided.

An Evaluation Of Carbon Indicators Of Soil Health In Long-Term Agricultural Experiments, D. Liptzin, C. E. Norris, S. B. Cappellazzi, G. Macbean, Andrew E. Suyker Et Al.

School of Natural Resources: Faculty Publications

No abstract provided.

Polycentric Governance In Nebraska, U.S., For Ground And Surface Water, T. Jedd, A. Schutz, M. Burbach

School of Natural Resources: Faculty Publications

No abstract provided.

Mexican And Central American Immigrants Entering A U.S. School At The Secondary Level, Der Aa Van

All-Inclusive List of Electronic Theses and Dissertations

The purpose of this qualitative cross-case study was to help provide insight for administrators, educators, and schools regarding the differences in the priorities of Mexican and Central American immigrant families and how parents are involved in their childrens education. One overarching question in this study is: How are immigrant families from Mexico and Central America involved in their childrens education within the United States school systems? Answering this question and understanding it will help school personnel be able to improve services for the education of immigrant students. Findings from this study include the priorities of Mexican and Central American immigrant …