Digital Commons Network^™

Prevalence And Characterization Of Antibiotic Resistant Strains Of Enterococcus Spp. And Acinetobacter Spp. In Community Household Environment, Niamh Dixon, Madison Reese, Monika Jirak, Alex Tush, Anuradha Ghosh

Posters

With increasing prevalence of antibiotic resistance threats, there is an upsurge in the occurrence of community-acquired infections. The purpose of this study is to assess the ecology and prevalence of Enterococcus spp. and Acinetobacter spp. (that are well-known antibiotic resistant nosocomial pathogens) in the household environment. Each household sampling kit contained 5 swabs for each of shoe bottom, restroom, cleaning supply, kitchen top, and door step/handle as well as a demographic data sheet to be filled up. A total of 30 such kits (n=150) have been processed. The swabs were subjected to enrichment using selective media for test bacterial species. …

El Laboratorio Cinegráfico De Pedro Pietri, Rojo Robles Mejias

Publications and Research

En su relato “Lost in the Museum of Natural History” Pedro Pietri se inserta en la narración como personaje y como fuente de historias inspiradas en la violencia de los géneros del western, los biker films y los melodramas. Esta aproximación a la experimentación literaria, la alteración sensorial y fílmica escenifica una crisis en la enunciación y la representación que hecha luces sobre las relaciones entre las desigualdades sociales, la violencia y la subjetividad.

Impact Of Behavioral Biases On Investment Decisions Of Fund Managers: Mediating Role Of Investor's Risk Perception During Covid-19, Bushra F. Malik, Anousha Iftikhar, Huma Ayub, Abida Ellahi

Accounting, Business Analytics, Economics, and Finance Department Faculty Articles

This study examined the relationship of one of the important factors observed during the COVID situation where different behavioral biases impact the risk perceptions and investment decisions of fund managers of Pakistan. Data has been gathered from fund managers of various organizations located in Rawalpindi and Islamabad through a structured questionnaire. The snowball sampling technique has been utilized. SPSS has been utilized for the data analysis. To test hypotheses, regression analysis has been done. The mediation and moderation results have been determined through Preacher and Hayes PROCESS macro. Model 7 of PROCESS macro has been utilized as it is best …

Metabolomic Analysis Of Trypanosoma Congolense And Leishmania Mexicana Treated With Selected Antiparasitic Drugs And In Silico Modelling Of Potential Drug Targets, Laurah Nyasita Ondari

All Master’s Theses

Animal African Trypanosomiasis (AAT) is a devastating parasitic disease caused by a variety of haemoflagellate extracellular protozoa of the genus Trypanosoma. It is endemic in 37 of the 55 countries in Africa and is transmitted by the obligate blood feeder of the genus Glossina. It affects both domestic and wild animals causing huge economic losses and severe health problems. Chemotherapeutic and prophylactic agents such as Isometamidium chloride (ISM) are used to prevent the progression of AAT in endemic areas. These agents face limitations such as resistance, toxicity, low efficacy, and unknown mechanisms of action. Therefore, it is crucial to develop …

Western Australian Sea Cucumber Resource Assessment Report, A.M. Hart, D.M. Murphy, F.F. Fabris

Fisheries Research Reports

No abstract provided.

Parenting, Neighborhood Characteristics, And Disruptive Child Behavior In Low-Income African American Families, Alyssa Buthman

Master's Theses and Doctoral Dissertations

The purpose of this study is to further examine the multifaceted relationship between parenting, neighborhood characteristics, and child disruptive behavior. Examining data from a low-income, African American preschool sample, this study investigated how self-reported neighborhood characteristics and observed parenting behaviors uniquely predicted observed disruptive behavior in children. Findings supported the strong relationship between parenting behaviors and child disruptive behavior where parenting sensitivity and engagement were predictive of fewer child disruptive behaviors while verbal and physical parenting interference and intrusiveness was predictive of greater disruptive child behavior. Neighborhood characteristics did not directly relate to parenting or child behaviors. However, neighborhood characteristics …

The Use Of Tiktok For Relationship Maintenance: An Exploratory Study, Shannon Nemes

Master's Theses and Doctoral Dissertations

The recent boom in popularity of the social media app TikTok has provided more opportunities for users in a committed relationship to express their love to their partner through features such as video sharing, tagging, or creating content together. The purpose of this study is to learn how romantic partners use TikTok to support relationship maintenance; in addition, this study draws on research related to the five love languages to gauge how romantic partners express their love for each other using TikTok. Interviews with eight individuals involved in long-term romantic relationships revealed how TikTok assists with relationship maintenance. Six themes …

Characterization Of Cofilin And Its Potential Role In The Epha4 Pathway, Brian Donald Condron

Master's Theses and Doctoral Dissertations

EphA4 is a receptor tyrosine kinase that is responsible for cellular adhesion and locomotion using repulsion signaling in early development of Xenopus laevis. EphA4 regulates cellular locomotion by controlling proteins within its signal transduction pathway, which may include the protein cofilin. Cofilin actively severs and removes actin monomers, thus altering the actin cytoskeleton, leading to the cessation of cellular crawl. During the gastrulation phase of embryonic development, individual cells are relocating to create the three primary germ layers of the organism. Failure of this process to occur results in attrition of the embryos, frequently by way of embryonic exogastrulation. …

Influence Of Social Cues On The Initiation Of Migratory Behavior In Red Crossbills (Loxia Curvirostra), John Bobo

Master's Theses and Doctoral Dissertations

The timing of migration is crucial for the fitness of organisms because mistimed migration can cause exposure to difficult conditions. Photoperiod drives migratory timing in many species, but little work has focused on how social cues might fine-tune migratory timing. The goal of this study is to determine if birds use social cues from conspecifics to fine-tune the initiation of migratory behavior and physiology. Red crossbills (Loxia curvirostra) are gregarious, nomadic migrants that make seasonal movements to find patchily-distributed conifer seeds and are responsive to social cues in the context of food. I test the hypothesis that social …

Southeast Ohio Winter/Spring 2022, E. W. Scripps School Of Journalism

Southeast Ohio Magazine

Table of contents:

Set in Stone
The father of statehood’s old home still stands ... 4

Pleased to Meat You
Fat Boy Q founder serves authentic BBQ ... 8

Safe Space and Coffee Cake
Cafe owner understands the importance of inclusion ... 10

Family Tested, Tastebud Approved
Two restaurants share a love for their customers .. 12

A Tale of Two Switzerlands
Two towns claim to be the “The Switzerland of Ohio” ... 14

Patchwork
Quilt barn trails started as an Adams County idea and grew into a national trend ... 16

Blood, Sweat and Alpaca Spit
The Cammas know …

Electrophysiological Responses To Conspecific Odorants In Xenopus Laevis Show Potential For Chemical Signaling, Heather J. Rhodes, Melanie Amo

Faculty Publications

No abstract provided.

Envenomation By A Gaboon Viper, Mary Claire Lark, Jarratt Lark

South Atlantic Division GME Research Day 2022

No abstract provided.

Perspectives On Primary Blast Injury Of The Brain: Translational Insights Into Non-Inertial Low-Intensity Blast Injury, Heather R. Siedhoff, Shanyan Chen, Hailong Song, Jiankun Cui, Ibolja Cernak, David X. Cifu, Ralph G. Depalma, Zezong Gu

Physical Medicine and Rehabilitation Publications

Most traumatic brain injuries (TBIs) during military deployment or training are clinically “mild” and frequently caused by non-impact blast exposures. Experimental models were developed to reproduce the biological consequences of high-intensity blasts causing moderate to severe brain injuries. However, the pathophysiological mechanisms of low-intensity blast (LIB)-induced neurological deficits have been understudied. This review provides perspectives on primary blast-induced mild TBI models and discusses translational aspects of LIB exposures as defined by standardized physical parameters including overpressure, impulse, and shock wave velocity. Our mouse LIB-exposure model, which reproduces deployment-related scenarios of open-field blast (OFB), caused neurobehavioral changes, including reduced exploratory activities, …

Saddling Up For Success: Rope Or Wrangle? Comparing Experiential Learning Programs For Developing Emotional Intelligence In The Workplace, Thomasa Sanchez

Dissertations from the Executive Doctorate in Business Administration Program

Emotional intelligence is characterized as the ability to jointly use intelligence and emotions to enhance reasoning. Corporate trainers have employed experiential learning methods to strengthen emotional competencies and often utilize experiential learning methods that involve challenge course programs that incorporate ropes and belay systems. A novel training method, equine-assisted learning, has recently gained traction and reportedly leverages the empathic nature of horses to enhance learning. This study had three primary purposes: (a) investigate the impact of a 1-day equine-assisted learning program upon emotional intelligence as compared to a 1-day challenge course program in a workplace population; (b) examine psychological safety …

The Covid-19 Pandemic And The Importance Of Financing The Biotechnology Industry In South Africa, Ramazan Uctu, Karen Eksteen

The Journal of Entrepreneurial Finance

Whether it is a government research institution, a public-private partnership, or a private enterprise, the South African biotechnology industry requires funding for the biotechnology industry. Our goal with this research is to look into the role of venture capital (VC) in financing biotech enterprises and demonstrate how VC finance could aid in the development of diagnostic kits and vaccines for Covid-19 or future pandemics in South Africa.

The study aims to provide policymakers with a clear image of the importance of funding the biotechnology sector, notably during the Covid-19 period, as recognized by the industry's key players. We employed a …

A Study Protocol To Prepare An Rbd Protein For Vaccine Against Covid-19, Z.M.G. Sarwar Jahangir, Arleta Helena Marnik

Publications and Research

Background: SARS-CoV-2 pandemic is a global threat to humans and the world’s economy. Effective and safe vaccines against this virus are essential to control and eradicate the pandemic. The currently applied vaccines carry SARS-CoV-2 spike-protein mRNA/cDNA. These vaccines go through several cellular processes in the recipients for producing antigens. On the contrary, the SARS-CoV-2 RBD (receptor binding domain)-protein is an antigen. It will directly stimulate antibody production against SARS-CoV-2. Hence, we propose to produce SARS-CoV-2 RBD-protein as a fast acting, effective and safe vaccine.

Methods: We propose to reconstruct a plasmid carrying three types of DNA sequences: RBD cDNA, FP …

Inflammatory Response To Sleep Fragmentation In Skeletal, Cardiac, And Smooth Muscle Tissues In Female Mice, Patton Allen

Mahurin Honors College Capstone Experience/Thesis Projects

Sleep is a critical process that the body undergoes. When sleep is interrupted, so that an individual is awakened for some period before going back into sleep, the sleep can be described as fragmented. Studies in the past have shown that sleep fragmentation (SF) promotes an inflammatory environment, especially in the brain and peripheral tissue. However, studies have not been conducted to observe inflammatory responses in muscle. To examine this, C57BL/6J female mice were subjected to either a control group (no SF) or a SF group which involved using an automated SF chamber to disrupt sleep every 2 min over …

The Impacts Of Reward Salience On Rate Of Learning & Extinction, Elise Crause, Mykayla Spurlin, Davis Eddleman, Lindsey Mathews, Sarah Headapohl

Science University Research Symposium (SURS)

Salience of rewards is a critical component to learning and motivation, without salience, motivation would be insubstantial (Berridge, 2012). This study aims to investigate the relationship between reward salience and rate of learning. Rate of learning will be measured by the number of correct lever presses within twenty-to-twenty-five-minute periods. Extinction will additionally be measured to further examine the impact reward salience has on learning. Using standard operant chambers, six female food-restricted rats were trained to lever press the left front lever to obtain a food reward. Rats were separated into two groups, (n=3 per group), an experimental group of rats …

Ms Environmental Biology Capstone Project, Dylan Brown

Regis University Student Publications (comprehensive collection)

Chapter 1- Revisiting Tamarisk Invasion in Riparian Ecosystems: An Argument Against Single Species Management of the Southwestern Willow Flycatcher (Empidonax traillii extimus)

Chapter 2- Temporal Trends of Tamarisk Remediation to Native Vegetation Establishment

Chapter 3- Assessing Effectiveness of Tamarisk Removal Treatments Through a Meta Regression Analysis

Chapter 4- Legal Challenges of Tamarisk Removal in the Southwestern United States

Office Of Sponsored Programs And Research Annual Report 2022, Office Of Sponsored Programs And Research

Office of Sponsored Programs and Research - Reports

It is with great pleasure that Academic Affairs shares with you our Office of Sponsored Programs and Research annual report for 2022-23. We are so very proud of our faculty members and staff who have used their expertise as educators and servant leaders to garner grants in the arts, education, business, health care, and student support.

The OSPR Annual Report details submitted proposals, proposals by College and university units, our diverse granting agencies and sponsors, and our new and active awards. We are delighted that in fiscal year 2022, we received 31 new awards in supporting the arts, the Family …

Justified, Evidently False Belief, Levi Yakuber

Bouwsma Paper Contest

In The Theory of Epistemic Rationality, Foley writes that the framing goal of epistemic rationality is, “now to believe those propositions which are true and now not to believe those propositions which are false,” with respect to non-trivial propositions.1 This “nowness” for truth distinguishes epistemic rationality from other domains of rationality, on the basis that epistemic rationality is concerned only with now believing what is true, regardless of what believing the truth will mean for one’s other goals as a person. Though very restrictive, this is the founding framework of the epistemic domain. Epistemic rationality being concerned only with the …

Rethinking Higher Education Models: Towards A New Education Paradigm For The Un 2030 Agenda For Sustainable Development, Jon-Hans Coetzer, Lucia Morales, Cormac Macmahon

Papers

The United Nations 2030 Agenda unfolded a comprehensive package of Sustainable Development Goals that seek global cooperation, participation, and coordinated efforts to 2030 for the betterment of humanity within the ecological constraints of the planet. However, it has become evident that the agenda is very ambitious and afflicted by a lack of solid governance principles vital to ensuring the successful achievement of the goals and targets. This paper offers critical insights into the pivotal role of higher education in promoting and implementing the goals. We argue that there is a need to raise awareness of the goals and educate relevant …

Re-Imagining Higher Education Through Equity, Inclusion And Sustainability (Rise): 2nd. Eut+ International Conference On Equality, Diversity And Inclusion, European University Of Technology

Conference Proceedings

No abstract provided.

An Adaptive Hegselmann–Krause Model Of Opinion Dynamics, Phousawanh Peaungvongpakdy

HMC Senior Theses

Models of opinion dynamics have been used to understand how the spread
of information in a population evolves, such as the classical Hegselmann–
Krause model (Hegselmann and Krause, 2002). One extension of the model
has been used to study the impact of media ideology on social media
networks (Brooks and Porter, 2020). In this thesis, we explore various
models of opinions and propose our own model, which is an adaptive
version of the Hegselmann–Krause model. The adaptive version implements
the social phenomenon of homophily—the tendency for like-minded agents to
associate together. This is done by having agents dissolve connections …

Re-Inventing Malignant Pleural Mesothelioma Therapeutics, Nishant S. Kulkarni

Theses and Dissertations

Malignant Mesothelioma (MM) is a rare malignancy affecting the mesothelial cells lining major physiological tissues. There is currently no cure for MPM and there is a growing need to bolster the therapeutic arsenal for MPM management. With that in mind, multiple small molecules were screened against MPM models, in-vitro, and it was revealed that Niclosamide (Niclo), an anthelmintic drug, was the most potent against MPM (IC50 values between 1.2-2.2 M) with the ability to inhibit colony formation in MPM cells and is efficacious against 3D tumor models. However, small molecule systemic therapy has resulted in negligible improvement in patient survival …

Evolving Evolutionary Psychology, Darcia Narvaez, David S. Moore, David C. Witherington, Timothy I. Vandiver, Robert Lickliter

Pitzer Faculty Publications and Research

Which evolutionary theory can best benefit psychological theory, research, and application? The most well-known school of evolutionary psychology has a narrow conceptual perspective (a.k.a., “Narrow Evolutionary Psychology” or NEP). Proponents of NEP have long argued that their brand of evolutionary psychology represents a full-fledged scientific revolution, with Buss (2020) recently likening NEP’s scientific impact to that of a Copernican or Darwinian paradigm shift. However, NEP stands on two traditions that are now the subjects of serious debate and revision: the neo-Darwinian adaptationist framework within evolutionary biology, and the computationalist “mind-as-computer” framework within cognitive science. Although NEP calls itself revolutionary, the …

Leveraging Developmental Psychology To Evaluate Artificial Intelligence, David S. Moore, Lisa M. Oakes, Victoria L. Romero, Koleen C. Mccrink

Pitzer Faculty Publications and Research

Artificial intelligence (AI) systems do not exhibit human-like common sense. The principles and practices of experimental psychology – specifically, work on infant cognition – can be used to develop and test AIs, providing insight into the building blocks of common sense. Here, we describe how the evaluation team for DARPA’s Machine Common Sense program is applying conceptual content, experimental design techniques, and analysis tools used in the field of infant cognitive development to the field of AI evaluation.

Impact Of Introductory Physics For The Life Sciences In A Senior Biology Capstone Course, Benjamin D. Geller , '01, Jack Rubien , '20, Sara Hiebert Burch, Catherine Hirshfeld Crouch

Physics & Astronomy Faculty Works

A goal of introductory physics for life sciences (IPLS) curricula is to prepare students to effectively use physical models and quantitative reasoning in biological and medical settings. To assess whether this goal is being met, we conducted a longitudinal study of the impact of IPLS on student work in later biology and chemistry courses. We report here on one part of that study, a comparison of written responses by students with different physics backgrounds on a diffusion task administered in a senior biology capstone course. We observed differences in student reasoning that were found to be associated with prior or …

Gender Differences In High School Students’ Perceptions Of Math And Science Identity, Self-Efficacy, And Utility, Lauren Mauel

All Electronic Theses and Dissertations

This quantitative dissertation examined the differences between young men and women’s perceptions of mathematics and science identity, self-efficacy, and utility. There are gender norms and stereotypes that impact identity, self-efficacy, and perceived utility of mathematics and science. The secondary data analyzed were drawn from the follow-up High School Longitudinal Survey (HSLS:09). The survey was administered to 20,594 11th-grade students enrolled at 904 eligible public, charter, and private schools from all states and the District of Columbia. The study investigated whether there are gender-based statistically significant (p < 0.05) differences in 11th grade students’ perceptions of mathematics and science identity, mathematics and science self-efficacy, and mathematics and science utility. The results of the study suggest that there are statistically significant differences between the genders in mathematics identity, science identity, mathematics self-efficacy, and science self-efficacy, but not statistically significant differences in mathematics utility and science utility. Continued research could prove useful to continue analyzing the gender gaps present.

Ifn-Γ Transforms The Transcriptomic Landscape And Triggers Myeloid Cell Hyperresponsiveness To Cause Lethal Lung Injury, Atul K. Verma, Michael Mckelvey, Md Bashir Uddin, Sunil Palani, Meng Niu, Christopher Bauer, Shengjun Shao, Keer Sun

Journal Articles: Pathology and Microbiology

Acute Respiratory Distress Syndrome (ARDS) is an inflammatory disease that is associated with high mortality but no specific treatment. Our understanding of initial events that trigger ARDS pathogenesis is limited. We have developed a mouse model of inflammatory lung injury by influenza and methicillin-resistant Staphylococcus aureus (MRSA) coinfection plus daily antibiotic therapy. Using this pneumonic ARDS model, here we show that IFN-γ receptor signaling drives inflammatory cytokine storm and lung tissue damage. By single-cell RNA sequencing (scRNA-seq) analysis, we demonstrate that IFN-γ signaling induces a transcriptional shift in airway immune cells, particularly by upregulating macrophage and monocyte expression of genes …