Digital Commons Network^™

Irruption, Ann Taylor

Appalachia

No abstract provided.

Research

Appalachia

Richard Primack’s work compares climate conditions Henry David Thoreau reported 150 years before to the current conditions, reports Jennifer Weeks. In western North America, the Sitka spruce struggles, writes Lisa Densmore Ballard.

Alpina

Appalachia

The 2013 pre-monsoon season in the Nepal Himalaya included first ascents of Jagdula, Dragmorpa Ri, and others, and a record number of deaths on several peaks, including eight on Everest. Briton Kenton Cool and Sherpa Dorje Gyalzen traversed three peaks in the Everest group. Sixteen Nepalese died in the Khumbu Icefall below Everest on April 18, 2014.

"Old Man" Thompson, White Mountain Guide: A Mountain Was Named After Him—And Then Unnamed, Julie Boardman

Appalachia

Julie Boardman’s story of Allen Thompson, a nineteenth-century White Mountain guide who had many excellent qualities and one failing: he focused on his own needs more than those of his clients.

118 Deer Went By...: Reminscing About The Old Sporting Camps Deep In The Maine Backcountry, William Geller

Appalachia

Part 2 of William Geller’s story of a vanished way of life in Maine, between Rainbow Lake and Yoke Pond just west of Millinocket and south of Baxter State Park. The story is told through the eyes of a caretaker looking back on the 1890s-1950s.

Waterman Fund Essay Winner: The Cage Canyon: "I Am Holding A Piece Of The Wild In My Hands, And She Wants Nothing To Do With Me", Jenny Kelly Wagner

Appalachia

The winner of the seventh Waterman Fund Essay Contest shows what has happened to wolves in the West: most wolves alive today have never learned to hunt because they were bred in captivity. They are a species that has lost its wildness but can never be tamed.

Save The Colorado: Can Recreation Rescue A Preservation Ethic?, John Gioia

Appalachia

An environmental management scholar takes a trip down the Colorado River and considers the long history of abuse that has threatened its water.

Appalachia Winter/Spring 2015: Complete Issue

Appalachia

No abstract provided.

The Beacon, February 25, 2022, The Beacon Staff

The Beacon, 2021-2022

Unsung Heroes: Patrick Hummel; When roomates become coworkers; Rap powerhouses rock the Super Bowl stage; Live-action characters disappoint audiences; An atmosphere filled with fun and letting go; A designer cultivating the art of theater with joy; Black History Month is celebrated; Social work travels to the Capitol; Why you should join O-Staff; A call to seek knowledge; Would you rather?; Raiders compete in GPAC indoor championship meet; Coach Korver achieves 500th win in coaching career; NW softball off to a strong start to the season; PGC pancakes were a success; Compass Center to host Adulting 101 sessions

Epigallocatechin-3-Gallate (Egcg): New Therapeutic Perspectives For Neuroprotection, Aging, And Neuroinflammation For The Modern Age, Ashley Payne, Samuel N. Nahashon, Equar Taka, Getinet M. Adinew, Karam F. A. Soliman

Agricultural and Environmental Sciences Faculty Research

Alzheimer's and Parkinson’s diseases are the two most common forms of neurodegenerative diseases. The exact etiology of these disorders is not well known; however, environmental, molecular, and genetic influences play a major role in the pathogenesis of these diseases. Using Alzheimer’s disease (AD) as the archetype, the pathological findings include the aggregation of Amyloid Beta (Aβ) peptides, mitochondrial dysfunction, synaptic degradation caused by inflammation, elevated reactive oxygen species (ROS), and cerebrovascular dysregulation. This review highlights the neuroinflammatory and neuroprotective role of epigallocatechin-3-gallate (EGCG): the medicinal component of green tea, a known nutraceutical that has shown promise in modulating AD progression …

Trident - Spring 2022, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.

Research And Rescue: Steps To Creating Your Own Self-Care Roadmap, Sara Fischer

All NNLM R2 Presentations

No abstract provided.

Miller Awarded $3.09 Million R01 To Study Drug Targets For Glioblastoma, Staff

Browse All News

No abstract provided.

Epitranscriptomic Reprogramming Is Required To Prevent Stress And Damage From Acetaminophen, Sara Evke, Qishan Li, Juan Andres Melendez, Thomas John Begley

Biological Sciences Faculty Scholarship

Epitranscriptomic marks, in the form of enzyme catalyzed RNA modifications, play important gene regulatory roles in response to environmental and physiological conditions. However, little is known with respect to how acute toxic doses of pharmaceuticals influence the epitranscriptome. Here we define how acetaminophen (APAP) induces epitranscriptomic reprogramming and how the writer Alkylation Repair Homolog 8 (Alkbh8) plays a key gene regulatory role in the response. Alkbh8 modifies tRNA selenocysteine (tRNA^Sec) to translationally regulate the production of glutathione peroxidases (Gpx’s) and other selenoproteins, with Gpx enzymes known to play protective roles during APAP toxicity. We demonstrate that APAP increases …

Clouded Precedent: Tandon V. Newsom And Its Implications For The Shadow Docket, Alexander Gouzoules

Buffalo Law Review

The Supreme Court’s “shadow docket”—the decisions issued outside its procedures for deciding cases on the merits—has drawn increasing attention and criticism from scholars, commentators, and elected representatives. Shadow docket decisions have been criticized on the grounds that they are made without the benefit of full briefing and argument, and because their abbreviated, per curiam opinions can be difficult for lower courts to interpret.

A spate of shadow docket decisions in the context of free-exercise challenges to COVID-19 public health orders culminated in Tandon v. Newsom, a potentially groundbreaking decision that may upend longstanding doctrines governing claims brought under the Free …

Development Of A Transcript To Record Learner Creativity And Curiosity, Prue Anderson, Toby Carslake, Anit Cherian, Bethany Davies, Laura Good, Jonathan Heard, Sladana Krstic, Brendan Mcginley, Dara Ramalingam, Sarah Richardson, Claire Scoular, Shani Sniedze, Jennifer Star

Assessment and Reporting

Funded with generous support by the Jacobs Foundation, the ultimate goal of this project was to develop transcripts to track learner progress in the domains of creativity and curiosity. To support this overarching goal, the research team sought to define creativity and curiosity in language that would resonate with learners and teachers and that would be appropriate across numerous cultural settings. The result of the project is a series of prototype materials and resources, specifically: literature reviews, frameworks, enabling environment summaries, reflective quizzes and transcripts. Based on insights from the literature reviews, the researchers developed frameworks to define the constructs …

The Diamond, February 25, 2022, Dordt University

Dordt Diamond

• Front Page: The Show Won't Go On - Prairie Grass Film Challenge Concludes After 15 Years; Mosaic Club Pieces Together Diverse Communities; International Students Share Culture at Fair
• News: New Design Studio Creates Prioritized Space for Graphic Design Students; Defender Grille Serves Up Some Competition
• Sports: Men's and Women's Basketball Stumble at Northwestern; Change in Leadership for Women's Volleyball; Dordt Hockey Triumphs
• Art & Entertainment: The Importance of Being Earnest Promises Laughter; Tall Girl 2 Falls Short; Demon Slayer: Kimetsu no Yaiba Takes the Stage; Death on the NIle - Three Unexciting Deaths; Uncharted - One …

Women Just Wanna Have Time: Wellness Innovation Research, Jessica Long, Julia Simon, Victoria Demartelly, Candice Norcott, Adrianne Dade

Journal of Wellness

Introduction: Studies show that the stress that resident physicians endure, particularly female residents, can have a negative impact on one’s overall well-being. Many interventional studies have explored the impact that mindfulness, meditation, and exercise have on stress, a negative influencer of well-being. The purpose of this study was to demonstrate how short, self-led mindfulness, meditation, and movement exercises impacted OB/GYN residents at a university-based program.

Methods: Participants voluntarily enrolled in a self-led program (fall 2019 – spring 2020) encompassing movement, mindfulness, and meditative activities, for which they received instructions by email detailing six 21-day cycles (requiring 15 minutes of daily …

Enhancing The Bioaccessibility Of Lycopene From Tomato Processing Byproducts Via Supercritical Carbon Dioxide Extraction, Ali Ubeyitogullari, Ozan N. Ciftci

Department of Food Science and Technology: Faculty Publications

Tomato peel and seed from tomato processing industry are treated as waste; however, they contain lycopene, a high-value bioactive compound. In this study, lycopene was extracted from tomato peel and seed using supercritical carbon dioxide (SC–CO₂) and hexane, and the bioaccessibilities of lycopene in the SC-CO₂- and hexaneextracted oleoresins were investigated for the first time. The (Z)-lycopene content of the SC-CO₂-extracted oleoresin (69%) was higher than that of hexane-extracted oleoresin (45%). Separation of the insoluble fraction from the oleoresins increased the (Z)-lycopene contents of the SC-CO₂- and hexane-extracted oil fractions to 80% …

Prepared For A Career In Patient Care, Callie Carr

UNH Today Archive

No abstract provided.

Targeting Angiogenesis In Squamous Cell Carcinoma Of The Head And Neck: Opportunities In The Immunotherapy Era, Nabil Saba, Pooja Vijayvargiya, Jan Vermorken, Juan Rodrigo, Stefan Willems, Nina Zidar, Remco De Bree, Antti Mäkitie, Greg Wolf, Athanassios Argiris, Yong Teng, Alfio Ferlito

Department of Medical Oncology Faculty Papers

Despite the lack of approved anti-angiogenic therapies in squamous cell carcinoma of the head and neck (SCCHN), preclinical and more recent clinical evidence support the role of targeting the vascular endothelial growth factor (VEGF) in this disease. Targeting VEGF has gained even greater interest following the recent evidence supporting the role of immunotherapy in the management of advanced SCCHN. Preclinical evidence strongly suggests that VEGF plays a role in promoting the growth and progression of SCCHN, and clinical evidence exists as to the value of combining this strategy with immunotherapeutic agents. Close to 90% of SCCHNs express VEGF, which has …

Mathematics From Scratch: Learning With Coding, Kimberly Beck, Jessica F. Shumway, Jody Clarke-Midura

Publications

Implementing successful cross-curricular lessons is challenging but possible. Participants in this session will learn about a partnership between Utah State University, Cache County School District, and Stanford University that has designed and implemented successful integrated mathematics-computer science lessons. Attendees will hear from researchers and in-service teachers on their experience with designing and carrying out the curriculum and will have an opportunity to view and interact with the computer programs that students used.

Heavy Metals In Harvested Rainwater Used For Domestic Purposes In Rural Areas: Yatta Area, Palestine As A Case Study., Fathi Anabtawi, Nidal Mahmoud, Issam A. Al-Khatib, Yung-Tse Hung

Civil and Environmental Engineering Faculty Publications

Rainwater harvesting is considered one of the most important water resources in the Palestinian countryside. In this research, the study area chosen for the study was Yatta town in Hebron city. 75 water samples were collected from 74 cisterns in a number of neighborhoods in Yatta, and a structured household survey was conducted with the same households where the water samples were collected. Statistical analysis was made using the SPSS software. An analysis for the samples was made using ICP-MS to test the existence of a number of heavy metals, namely Pb, Cr, Mn, Co, Ni, Cu, Zn and Cd. …

Employee Accomplishment Report 2020 - 2021, Cynthia S. Dancel

Libraries' Documents

No abstract provided.

Initial Soil Conditions Outweigh Management In A Cool-Season Dairy Farm's Carbon Sequestration Potential, Kyle A. Arndt, Eleanor E. Campbell, Chris D. Dorich, A. Stuart Grandy, Timothy S. Griffin, Peter Ingraham, Apryl L. Perry, Ruth K. Varner, Alexandra R. Contosta

Faculty Publications

Pastures and rangelands are a dominant portion of global agricultural land and have the potential to sequester carbon (C) in soils, mitigating climate change. Management intensive grazing (MIG), or high density grazing with rotations through paddocks with long rest periods, has been highlighted as a method of enhancing soil C in pastures by increasing forage production. However, few studies have examined the soil C storage potential of pastures under MIG in the northeastern United States, where the dairy industry comprises a large portion of agricultural use and the regional agricultural economy. Here we present a 12-year study conducted in this …

Volume Cxli, Number 7, February 25, 2022, Lawrence University

The Lawrentian

No abstract provided.

Identification Of Kidney Injury Released Circulating Osteopontin As Causal Agent Of Respiratory Failure, Fatima Zohra Khamissi, Liang Ning, Eirini Kefaloyianni, Hao Dun, Akshayakeerthi Arthanarisami, Amy Keller, Jeffrey J Atkinson, Wenjun Li, Brian Wong, Sabine Dietmann, Kory Lavine, Daniel Kreisel, Andreas Herrlich

Open Access Publications

Tissue injury can drive secondary organ injury; however, mechanisms and mediators are not well understood. To identify interorgan cross-talk mediators, we used acute kidney injury (AKI)-induced acute lung injury (ALI) as a clinically important example. Using kidney and lung single-cell RNA sequencing after AKI in mice followed by ligand-receptor pairing analysis across organs, kidney ligands to lung receptors, we identify kidney-released circulating osteopontin (OPN) as a novel AKI-ALI mediator. OPN release from kidney tubule cells triggered lung endothelial leakage, inflammation, and respiratory failure. Pharmacological or genetic OPN inhibition prevented AKI-ALI. Transplantation of ischemic

Simian Immunodeficiency Virus Infection Mediated Changes In Jejunum And Peripheral Sars-Cov-2 Receptor Ace2 And Associated Proteins Or Genes In Rhesus Macaques, Nongthombam Boby, Xuewei Cao, Kelsey Williams, Shiva Kumar Goud Gadila, Monica N. Shroyer, Peter J. Didier, Sudesh K. Srivastav, Arpita Das, Kate Baker, Qiuying Sha, Bapi Pahar

Michigan Tech Publications, Part 1

Angiotensin converting enzyme-2 (ACE2) and associated proteins play a pivotal role in various physiological and pathological events, such as immune activation, inflammation, gut barrier maintenance, intestinal stem cell proliferation, and apoptosis. Although many of these clinical events are quite significant in SIV/HIV infection, expression profiling of these proteins has not been well reported. Considering the different pathological consequences in the gut after HIV infection, we hypothesized that the expression of ACE2 and associated proteins of the Renin-angiotensin system (RAS) could be compromised after SIV/HIV infection. We quantified the gene expression of ACE2 as well as AGTR1/2, ADAM17, and TMPRSS2, and …

An Analysis Of Community-Based Values Informing Land Management On The Midwestern Prairie Band Potawatomi Nation Of Kansas, Usa, Heidi Mehl, Diana L. Restrepo-Osorio, Melinda Howard, Cynthia Annett

IGC Proceedings (1977-2023)

The focus of this study is to examine the interface between land management practices and values within a tribal community in rural midwestern North America. The Prairie Band Potawatomi Nation (PBPN) reside on a tribal reservation with a checkerboard distribution amongst private, non-tribal landowners. Previous studies have indicated that landowners may have different value-systems leading to variations in land-management practices. This can impose discontinuous land management in areas within shared biological boundaries, such as watersheds, especially between tribal and non-tribal entities. Preliminary spatial analysis in and around the PBPN landscape determined that the tribally-managed lands present more vegetative cover per …

A Policy Brief On Adopting The Somali Camel For Enhanced Profitability And Pastoral Resilience In Northern Kenya, Simon G. Kuria, A. O. Adongo, S. Murithi, O. K. Koech, J. T. Njoka, P. Kamande

IGC Proceedings (1977-2023)

Persistent drought and high temperatures in Isiolo and Marsabit counties of northern Kenya repeatedly devastate livestock herds particularly cattle making the pastoralists less resilient, more vulnerable to climate change and poor. To address this challenge, an IGAD funded project promoted adoption of Somali camel breed, trained farmers on improved management and also estimated potential profitability of rearing the camel. Through the project, trainers were trained and facilitated to train 240 peri-urban Somali camel producers in Isiolo and Marsabit on breeding, health, routine husbandry and marketing. Impact study documenting positive stories of change was conducted at the end. Producers who hitherto …