Digital Commons Network^™

A Little Blue Hedgehog That Runs A Lot And Has An Attitude: An Analysis Of The Covers Of Archie Comics’ Sonic The Hedgehog, Eleanor Herman

Theses and Dissertations

Through the lens of Robin Williams principles of design as outlined in her book, The Non-Designer’s Design Book, this thesis analyzes selected covers of Archie Comics’ Sonic the Hedgehog comic book series to see how the covers evolved over time, as the nearly 25-year continuous run allows for a unique analysis opportunity. 18 issues were selected and analyzed, with conclusions drawn from the covers’ use of contrast, alignment, repetition, and proximity.

The Gut Microbiota Shapes The Human And Murine Breath Volatilome, Ariel J. Hernandez-Leyva, Amalia Z. Berna, Maggie H. Bui, Yang Liu, Anne L. Rosen, Michael A. Lint, Samantha A. Whiteside, Natalia Jaeger, Nikhilesh Joardar, Wentai Luo, Multiple Additional Authors

Chemistry Faculty Publications and Presentations

The gut microbiota is crucial to health, yet implementation of microbiota-based therapeutics is limited by the lack of rapid diagnostics. We hypothesize that breath contains gut microbe-derived volatile organic compounds (VOCs) reflecting microbiota composition and metabolism. In healthy children, we found that breath VOC composition (or volatilome), assessed by gas chromatography-mass spectrometry, correlates with gut microbiome composition and function. By capturing exhaled breath from human-stool-colonized and monocolonized gnotobiotic mice, we profiled breath VOCs and discovered that murine breath is also significantly influenced by the gut microbiome. VOCs from cultured gut microbes were identified in vivo in monocolonized gnotobiotic colonized mice. …

Cdk2 Inhibitor Blu-222 Synergizes With Cdk4/6 Inhibitors In Drug Resistant Breast Cancers Through P21/P27 Induction, Linjie Luo, Yan Wang, Tuyen Bui, Xiaoting Jiang, Mei-Kuang Chen, Xiayu Rao, Sepideh Mohammadhosseinpour, Mi Li, Serena Kim, Rachel Y Kim, Saba Kamaliasl, Carmen W Ulizio, Spyros Tsavachidis, Juliana Navarro-Yepes, Nicole M Kettner, Hannah Wingate, Funda Meric-Bernstam, Kelly K Hunt, Jing Wang, Kerrie Faia, Khandan Keyomarsi

Faculty, Staff and Student Publications

Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) combined with endocrine therapy are the standard first-line treatment for hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer, but resistance inevitably develops. In triple-negative breast cancer (TNBC), the efficacy of CDK4/6i remains uncertain. Our study shows that the selective CDK2 inhibitor BLU-222, while effective alone, enhances synergistic activity when combined with CDK4/6i in resistant HR+/HER2- and TNBC models, leading to increased apoptosis and cell cycle arrest. In vivo, combining BLU-222 with palbociclib or ribociclib produced significant antitumor activity across eight resistant models, driving durable tumor regression and prolonged survival. Mechanistically, BLU-222, alone or with palbociclib, upregulated …

Cdk2 Inhibitor Blu-222 Synergizes With Cdk4/6 Inhibitors In Drug Resistant Breast Cancers Through P21/P27 Induction, Linjie Luo, Yan Wang, Tuyen Bui, Xiaoting Jiang, Mei-Kuang Chen, Xiayu Rao, Sepideh Mohammadhosseinpour, Mi Li, Serena Kim, Rachel Y Kim, Saba Kamaliasl, Carmen W Ulizio, Spyros Tsavachidis, Juliana Navarro-Yepes, Nicole M Kettner, Hannah Wingate, Funda Meric-Bernstam, Kelly K Hunt, Jing Wang, Kerrie Faia, Khandan Keyomarsi

Faculty, Staff and Student Publications

Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) combined with endocrine therapy are the standard first-line treatment for hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer, but resistance inevitably develops. In triple-negative breast cancer (TNBC), the efficacy of CDK4/6i remains uncertain. Our study shows that the selective CDK2 inhibitor BLU-222, while effective alone, enhances synergistic activity when combined with CDK4/6i in resistant HR+/HER2- and TNBC models, leading to increased apoptosis and cell cycle arrest. In vivo, combining BLU-222 with palbociclib or ribociclib produced significant antitumor activity across eight resistant models, driving durable tumor regression and prolonged survival. Mechanistically, BLU-222, alone or with palbociclib, upregulated …

Public Speaking, Demonstration And Action Exhibit Scorecard & Information, Alison Coleman

UNH Cooperative Extension

No abstract provided.

Poster Scoresheets 2026, Alison Coleman

UNH Cooperative Extension

No abstract provided.

Targeting Smpdl3b To Ameliorate Radiation- And Cisplatin-Induced Renal Toxicity, Youssef Zeidan

All Publications

Kidney toxicity remains a major dose-limiting complication of radiation therapy and platinum-based chemotherapy, yet the molecular determinants of renal susceptibility and resilience to these genotoxic treatments are incompletely understood. Podocytes are particularly vulnerable to such insults, and emerging evidence implicates lipid dysregulation in podocyte injury. This study investigated the role of sphingomyelin phosphodiesterase acid-like 3B (SMPDL3B), a podocyte-enriched lipid-modulating enzyme, in radiation- and cisplatin-induced nephrotoxicity. Using a doxycycline-inducible, podocyte-specific SMPDL3B transgenic mouse model, renal injury was assessed following focal kidney irradiation, cisplatin administration, or their combination through functional assays, histopathology, ultrastructural analysis, immunofluorescence, and targeted lipidomics. Combined radiation and cisplatin …

Kenyon Collegian - January 22, 2026

The Kenyon Collegian

No abstract provided.

Restorative Justice, Human Dignity, And The Capabilities Approach, Reed Mcfeely

Acta Cogitata: An Undergraduate Journal in Philosophy

As a value-driven and transformative approach to criminal justice, restorative justice is inherently philosophical. Despite this, however, its philosophical underpinnings remain underdeveloped. This manuscript argues for the necessity of grounding restorative justice in moral philosophy, specifically through the framework offered by Martha Nussbaum’s capabilities approach. The paper first addresses the fragmented nature of restorative justice values, suggesting a new uniform framework centered on respect, equality, agency, and active striving. It then explores what victims are materially owed in the restorative justice process, advancing Nussbaum’s list of basic capabilities as a foundation. However, the central aim of this manuscript transcends these …

"Region 5 Report" United Auto Workers Newsletter From August , 1969

Migrant Farm Workers Organizing Movement Collection

"Region 5 Report" from the United Auto Workers newsletter dated August, 1969. The document contains news from region 5 such as " Grape boycott program expands to Kansas City and Texas".

"El Malcriado" Newspaper From June, 1967

Migrant Farm Workers Organizing Movement Collection

"El Malcriado" newspaper from June, 1967 edition. The newspaper reports on the arrest of 19 people on May 26 by the Texas Rangers.

"El Malcriado" Newspaper From May 24, 1967

Migrant Farm Workers Organizing Movement Collection

"El Malcriado" newspaper May 24, 1967 edition. The newspaper states updates on new objectives of the union and also on "the fight to save Texas". The document also includes a history portion about the fight for textile workers in the 19th and 20th century for better working conditions.

Saviano, Garrone, Gomorrah: Neorealism And Noir In The Land Of The Camorra, Fabrizio Cilento

Fast Capitalism

No abstract provided.

Facebook Killed The Reunion Star: How Facebook Is Changing Who We Are And What We Do, Sara Ridenour

Fast Capitalism

No abstract provided.

Colonial Whaling In Walvis Bay And In Southern Africa: Environmental Exploitation And Legacy Of South Africa’S Cetaceans, Jake L. Zarak

Swarthmore Undergraduate History Journal

This paper examines the colonial whaling industry in Southern Africa, with a focus on Walvis Bay, tracing its long term environmental and socio-economic impacts. From the 1700s to the 1900s, whaling operations, primarily led by American, British, and French enterprises, exploited the region’s rich populations of sperm and right whales, drastically reducing their numbers. The study contextualizes whaling within a broader colonial framework, analyzing its effects on whale migratory patterns, indigenous communities, and marine ecosystems. It explores as well, the transition from whaling as an economic endeavor to modern conservation efforts and the romanticization of whales in literature and art. …

Western Mansions In The Gardens Of Perfect Brightness, Another History Of High Qing Sino-European Exchanges, Nicolas Woreth

Swarthmore Undergraduate History Journal

The Gardens of Perfect Brightness, the favorite residence of Chinese Emperors in the High Qing era (1683-1799), held mysteries that will remain forever concealed from the public eye after French and British imperialist forces looted it and burned it beyond repair during the Second Opium War (1856-1860). Behind the doors of the secret garden, scarcely open to anyone but the emperor, his wives, and servants, worked European artists and scientists. Most of them were Jesuit missionaries who served the emperor in the hope of gaining his favor and support for the spread of Christianity in China.

This paper aims to …

Satire, Guns, And Humans: Lessons From The Nacirema, Steve Kroll-Smith, Gwen Hunnicutt

Fast Capitalism

No abstract provided.

All The Rage: Digital Bodies And Deadly Play In The Age Of The Suicide Bomber, Carolyn Guertin

Fast Capitalism

No abstract provided.

Mediated Ritual On Academic Ground, Neal King

Fast Capitalism

No abstract provided.

Henry David Thoreau: The Beginnings Of Fast Capitalism, Charles Lemert

Fast Capitalism

Author Biography

Charles Lemert, Wesley University Emeritus Professor of Sociology at Wesleyan University

Beyond Prepper Culture As Right-Wing Extremism: Selling Preparedness To Everyday Consumers As How To Survive The End Of The World On A Budget, Timothy W. Luke

Fast Capitalism

No abstract provided.

Create @ State 2022, Arkansas State University - Jonesboro

Create@State

The proceedings book for 2022

Create @ State 2019, Arkansas State University - Jonesboro

Create@State

The proceedings book for 2019

Deep-Rooted Images: Situating (Extra) Institutional Appropriations Of Deepfakes In The Us And India, Kailyn Slater, Akriti Rastogi

Fast Capitalism

The paper aims to map institutional and extra-institutional affordances and appropriations of deepfake images through an analytical framework that accounts for the socio-political contexts of the US and India. Our main argument involves the inevitable leakage of technologies outside institutions and its redressal through corporatized comebacks. Utilizing vernacular and global examples, we trace the perceived ownership and extended modalities of deepfake images and videos. While compositing (Manovich 2006) and habitual media (Chun 2016) predetermine our deep mediatized world (Hepp 2019), deepfakes, as a visual cultural technology newly popular within the political economy of media, offer a novel entry point into …

Cultural Politics And The Crisis Of Education And Political Agency, Henry Giroux

Fast Capitalism

No abstract provided.

The Manosphere As An Online Protection Racket: How The Red Pill Monetizes Male Need For Security In Modern Society, Eva Bujalka, Tim Rich, Stuart Bender

Fast Capitalism

To effectively manage, empathize with and respond to the implications and impact of the so-called ‘Manosphere,' this paper is centered on the premise that researchers require an understanding of the draw factors that lead individuals to engage, affiliate with, and contribute to the various groups that constitute this wider movement. This paper seeks to contribute to the growing body of knowledge around the Manosphere by exploring how thought leaders propagate symbiotic cycles of ontological security and insecurity through YouTube in a manner that resembles a protection racket. It argues that these constructed ontological security cycles provide a powerful impetus to …

Full Issue, Fast Capitalism Editorial Team

Fast Capitalism

No abstract provided.

The United Farm Workers Organizing Committee August Newsletter

Migrant Farm Workers Organizing Movement Collection

August newsletter from the United Farm Workers Organizing Committee (UFWOC). The document mentions the aspect of "free enterprise" or the "American way of life".

Vital Environs: Ecologies Of Modernism And The Nature Tradition, Danielle Nasenbeny

Dissertations

Vital Environs: Ecologies of Modernism and the Nature Tradition is an investigation of late nineteenth and early twentieth century British literature that explores the space between the individual and the external world. The project begins by exploring the “mind-body problem,” which is a topic in philosophy that recognizes the difficulty in understanding how the mind emerges from physical matter. While this topic has been in discussion since at least Descartes, science is still making crucial discoveries that challenge our understanding of this connection. I argue that the environmental crisis we find ourselves in today is a mind-body problem of global …

Dairy And Food Science Student Newsletter, January 21, 2026, Department Of Dairy And Food Science

Dairy and Food Science Student Newsletter

No abstract provided.