Digital Commons Network^™

Adjuvant 5-Fluorouracil/Leucovorin, Capecitabine, And Oxaliplatin-Related Regimens For Stage Ii/Iii Colon Cancer Patients 66 Years Or Older, Emily Jones, Zhigang Duan, Thinh T Nguyen, Sharon H Giordano, Hui Zhao

Faculty, Staff and Student Publications

Adjuvant chemotherapy of leucovorin-modulated 5-fluorouracil (5-FU/LV), capecitabine, and adding oxaliplatin to 5-FU/LV or capecitabine (FLOX/OX) have been standard regimens for high-risk stage II or III colon cancer (CC). We aimed to evaluate their patterns of use, association with survival, and rate of emergency room visit (ER) or hospitalization during the treatment period. High-risk stage II or III patients aged >65 years diagnosed between 2007 and 2015, underwent colectomy, and received any of these three regimens were selected from SEER and Texas Cancer Registry (TC) linked with Medicare data. Chi-square test, Kaplan-Meier survival curves, Cox regression, and logistic regression were used …

Challenges And Opportunities In Academic Physiatry: An Environmental Scan, David C Morgenroth, Tiffany Knowlton, Susan Apkon, Cheri A Blauwet, Anthony S Burns, Cecilia Córdova Vallejos, Walter Frontera, Sandra L Hearn, Prakash Jayabalan, Peter A Lim, Alex Moroz, Danielle Perret, Danielle Powell, Matt Puderbaugh, W Evan Rivers, Gwendolyn Sowa, Monica Verduzco-Gutierrez, Pablo A Celnik

Faculty, Staff and Students Publications

Environmental scans determine trends in an organization's or field's internal and external environment. The results can help shape goals, inform strategic decision making, and direct future actions. The Association of Academic Physiatrists convened a strategic planning group in 2020, composed of physiatrists representing a diversity of professional roles, career stages, race and ethnicity, gender, disability status, and geographic areas of practice. This strategic planning group performed an environmental scan to assess the forces, trends, challenges, and opportunities affecting both the Association of Academic Physiatrists and the entire field of academic physiatry (also known as physical medicine and rehabilitation, physical and …

Extremism In America: Explaining Variations In Ideologically Motivated Fatal Violence, Celinet Duran

Dissertations, Theses, and Capstone Projects

This dissertation uses data from the United States Extremist Crime Database (ECDB) to assess the nature of extremist violence between left-wing, far-right and al-Qaeda and associated movements (AQAM) inspired ideological fatal violence. It extends the empirical literature on extremist violence in three significant ways by: (1) expanding an existing database to provide a comparative component that is both timely and policy-relevant and conveys a more complete picture of the nature of domestic extremism in the U.S.; (2) systematically comparing extremist violence across the left-wing, far-right and AQAM ideologies to better assess the nuances of extremist violence; and (3) applying empirical …

Supreme Court Justice Brett Kavanaugh: 2023 Notre Dame Law Review Federal Courts Symposium, Marcus Cole, Brett Kavanaugh

2019–Present: G. Marcus Cole

Jan 26, 2023

NOTRE DAME LAW SCHOOL

U.S. Supreme Court Associate Justice Brett Kavanaugh covered a range of topics during a keynote Q&A at the 2023 Notre Dame Law Review Federal Courts Symposium, held on January 23 in the McCartan Courtroom. Justice Kavanaugh was joined by G. Marcus Cole, the Joseph A. Matson Dean and Professor of Law at Notre Dame Law School, and responded to questions from students and faculty members in the audience.

Forgotten "People": Reviving Textualism In The Fourth Amendment, Peter C. Douglas

San Diego Law Review

For more than a century, the Supreme Court has struggled to develop a coherent and sustainable theory of the Fourth Amendment. Before the ink is dry on a new Fourth Amendment opinion, it is cabined, abrogated, or outright overruled. As one scholar has commented, the “evolution of Fourth Amendment doctrine over the past century bears a striking resemblance to Hamlet’s descent into insanity.” While the Court vacillates between “theories” of the Fourth Amendment that might bring clarity to a difficult body of constitutional law, the rights it bespeaks lie vulnerable and unprotected. This Article argues that the problem flows from …

Substrate Electronics Dominate The Rate Of Reductive Dehalogenation Promoted By The Flavin-Dependent Iodotyrosine Deiodinase, Jeffrey M Carlson, Ayzsa Tannis, Kate R Woodworth, Megan R Reynolds, Neha Shinde, Breanne Anderson, Keivon Hobeheidar, Aisha Praag, Kristen Campbell, Cynthia Carpentieri, Teri Willabus, Elizabeth Burkhardt, Elizabeth Torrone, Kevin P O'Callaghan, Kathryn Miele, Dana Meaney-Delman, Suzanne M Gilboa, Emily O'Malley Olsen, Van T Tong

Faculty, Staff and Student Publications

Despite universal prenatal syphilis screening recommendations and availability of effective antibiotic treatment, syphilis prevalence during pregnancy and the incidence of congenital syphilis have continued to increase in the United States (1,2). Concurrent increases in methamphetamine, injection drug, and heroin use have been described in women with syphilis (3). CDC used data on births that occurred during January 1, 2018-December 31, 2021, from two states (Arizona and Georgia) that participate in the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET) to describe the prevalence of substance use among pregnant persons with syphilis by congenital syphilis pregnancy outcome (defined …

Alcohol Consumption And Epigenetic Age Acceleration In Young Adults, Drew R Nannini, Lei Liu, Et Al.

2020-Current year OA Pubs

Alcohol is a widely consumed substance in the United States, however its effect on aging remains understudied. In this study of young adults, we examined whether cumulative alcohol consumption, i.e., alcohol years of beer, liquor, wine, and total alcohol, and recent binge drinking, were associated with four measures of age-related epigenetic changes via blood DNA methylation. A random subset of study participants in the Coronary Artery Risk Development in Young Adults Study underwent DNA methylation profiling using the Illumina MethylationEPIC Beadchip. Participants with alcohol consumption and methylation data at examination years 15 (

Haitian Immigrants' Information Needs And Behaviors: Libraries, Information Professionals And Haitians In The United States, Natasha Finnegan

School of Information Student Research Journal

Haitian immigrants are a socially excluded growing demographic in the United States that deals with racism, anti-immigrant sentiment, anti-Haiti rhetoric, and language barriers. Information professionals need to understand Haitian information behavior, their cultural preferences, and barriers in order to successfully fulfill their information needs. This article examines other disciplines’ relevant and scholarly research literature on Haitian immigrants in the United States to discover their trends of information behavior and barriers so that the Library and Information Science field can create effective information pathways to support their community. Haitian immigrants turn to their families and trusted individuals for their information needs, …

The Openness Of Talmud, Bruce Ledewitz

Ledewitz Papers

Published scholarship collected from academic journals, law reviews, newspaper publications & online periodicals.

Machine Learning Algorithms Improve Modis Gpp Estimates In United States Croplands, D. Menefee, T. O. Lee, K. C. Flynn, J. Chen, M. Abraha, J. Baker, A. Suyker

School of Natural Resources: Faculty Publications

No abstract provided.

Changing Blowfly (Diptera: Calliphoridae) Populations In Orlando, Florida, United States, A. Roe, R. J. Barnes, Leon G. Higley, N. H. Haskell

School of Natural Resources: Faculty Publications

No abstract provided.

Barriers To And Facilitators Of Military Spouses’ Recovery From Perinatal Mental Health Disorders: A Qualitative Study, My Hanh (Theresa) Nguyen, Semira Semino-Asaro, Alison M. Reminick, Amber T. Rukaj, Cynthia D. Connelly

School of Nursing and Health Science: Faculty Scholarship

Introduction: Perinatal mental health disorders (PMHDs) are a common complication of child-bearing, affecting approximately 1 in 7 U.S. mothers. An expanding literature has examined how PMHDs afect military families; however, little is known about military spouses’ experiences in accessing and engaging in treatment for PMHDs. Te purpose of this qualitative study was to gain a better understanding of the barriers to and facilitators of accessing, engaging, and progressing in treatment and recovery among a sample of U.S. military spouses with PMHDs. Methods: Military spouses (N = 12) were recruited from a maternal mental health clinic at an academic …

Historical And Future Projections Of Supercell Precipitation Contributions To The Hydroclimate Of The United States, Aaron Zeeb

Graduate Research Theses & Dissertations

Rotating storms, or supercells, are frequent producers of significant tornadoes, hail, and nontornadic winds and an underappreciated genitor of extreme precipitation rates and flash floods. Little research has examined the precipitation contributions from supercells to the overall hydroclimate of the CONUS and, provided that these storms and their precipitation rates may shift in the future due to climate change, it is important to understand their characteristics from both historical and future perspectives. This research seeks to understand supercell precipitation characteristics across the CONUS using high-resolution, convection-permitting, dynamical-downscaled simulations for three, 15-year epochs. Epochs include a historical end-of-20th-century period (1990–2005) and …

Droughtscape, Winter 2023, National Drought Mitigation Center

DroughtScape: Quarterly Newsletter of the National Drought Mitigation Center (2007–2023)

DroughtScape, Winter 2023

A Unique Hiv Harm Reduction Perspective From Costa Rica: Hogar De La Esperanza An Ethnographic Case Study And Comparative Examination Of Approach To Hiv Treatment Between The United States And Costa Rica, Kim Marie Day

Theses and Graduate Projects

This case study presents a real, currently operational scenario of harm reduction in action in Costa Rica, focusing on its success and the challenges faced by healthcare professionals, the experiences of those who live at Hogar de la Esperanza, and the implications for healthcare policies and interventions in the United States. By examining this specific case of a Costa Rican community-based HIV treatment model, the aim of this ethnographic report is to shed light on the complexities and factors contributing to the success or failure of harm reduction treatment strategies within the United States and what can be learned by …

Growing Up Ghanaian: The Well-Being Of Ghanaian Children In The United States And Ghana, Akua Bemma Opoku

Dissertations and Theses

Children’s subjective well-being is a child’s judgment of their well-being. Subjective well- being can have positive and negative indicators. Positive indicators include but are not limited to safety, feeling happy, and feeling excited. Negative indicators include but are not limited to lack of safety, lack of confidence, and sadness. Children’s ethnic background and their relation to their ethnic background may influence their subjective well-being. Research focusing on ethnic identity and child well-being has found positive associations. Research has also found a relationship between the context of family, school, peers, religion, community, and ethnic identity. This comparative phenomenological study aimed to …

Through A Lens Of Genocide: A Different Approach For Hate Crimes Legislation, Bruce Ching

Journal Articles

Hate crimes perpetrators select their victims based on the victims’ identity groups. Policies underlying legislation against hate crimes recognize that such crimes inflict greater harm on society than do the same actions committed for non-biased motives. Genocide may be conceptualized as hate crimes writ large; conversely, a new model of hate crimes legislation might be patterned on legal concepts of genocide scaled down to state or local levels. This new recognition could successfully address criticisms from both liberal and conservative factions along the political spectrum, offering a model that state and local governments could invoke for dealing with bias-motivated incidents …

Blood & Chemical Testing_ What You Need To Know And Why You Need To Know It, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held August 24-25, 2023.

Doris Stevens: A "Fascist" Feminist? Stevens, The Inter-American Commission Of Women, And The Unión Argentina De Mujeres, 1936-1939, Jeannette Hunker

Scripps Senior Theses

Doris Stevens (1888-1963) was a U.S. feminist, suffragist, and member of the National Women’s Party. After the Nineteenth Amendment to the U.S. Constitution was ratified in 1920, Stevens, among other U.S. feminists, involved herself in Latin American politics, working to pass women’s suffrage legislation in multiple countries. Stevens was chair of the Inter-American Commission of Women (IACW) from 1928 to 1939. Eventually, a number of Latin American feminists, as well as members of the Roosevelt administration, sought to remove her from the IACW when her political tendencies posed a threat to both. Accused of being a “fascist,” Stevens was voted …

Evil No More: The Image Of The Witch And Women In The United States From Seventeenth And Twentieth Centuries, Morgan Taylor Peacha

CGU Theses & Dissertations

Women in both colonial America and the twentieth century United States were impacted by the notions of witches and witchcraft. There was an integral change in witchcraft during the era of growing feminism and equality in political status. In the colonial period, what was once a disguise for women's oppression, has become a tool for women's liberation.

Convolutional-Neural-Network-Based Des-Level Aerodynamic Flow Field Generation From Urans Data, John P. Romano, Oktay Baysal, Alec C. Brodeur

Mechanical & Aerospace Engineering Faculty Publications

The present paper culminates several investigations into the use of convolutional neural networks (CNNs) as a post-processing step to improve the accuracy of unsteady Reynolds-averaged Navier–Stokes (URANS) simulations for subsonic flows over airfoils at low angles of attack. Time-averaged detached eddy simulation (DES)-generated flow fields serve as the target data for creating and training CNN models. CNN post-processing generates flow-field data comparable to DES resolution, but after using only URANS-level resources and properly training CNN models. This document outlines the underlying theory and progress toward the goal of improving URANS simulations by looking at flow predictions for a class of …

Childless African American Women Over 50 In The Usa: A Qualitative Descriptive Study, Robbie Roshyl Mitchell

Theses and Dissertations

In modern society, some African American women are choosing a career before accepting the traditional role of birthing a child or children at an early age and marriage is not always part of the equation. Women’s freedoms (i.e., equality, personal choice, sexuality) have increased since their early struggles for their rights as citizens and as women. Some are viewed as agents against the norm by some conservative-minded people by not having a child or children well into their adulthood, especially if they are over the age of 50. Research suggests that women without children are perceived negatively by others and …

Transnational Dominican Activism: Documenting Grassroots Social Movements Through Esendom, Nelson Santana, Amaury Rodriguez, Emmanuel Espinal

Publications and Research

Dominican-descended people are one of the most dynamic Caribbean and Latin American ethnic and cultural communities in the United States. Whether in the Dominican Republic or as members of a transnational community, the Dominican population has a long and rich history of challenging the powers that be, confronting unjust acts, and opposing oppressive laws within the communities they inhabit through their civic engagement. This paper addresses one question: As Dominican society and the world have evolved, what has been the role of U.S.-based online media in sustaining, disseminating, and rescuing the long tradition of civic involvement and struggle exemplified by …

U.S. College Students’ Perspectives On Contraception And Abortion Post-Dobbs: The Influence Of Socioeconomic Privilege And Gender Inequity, Emily S. Mann, Jessica A. Mclennan, Kathleen Broussard

Faculty Publications

This study examined college students’ perspectives about contraception and abortion in the context of the United States Supreme Court’s decision to eliminate the constitutional right to abortion in June 2022. Individual, semi-structured interviews were conducted between October 2022 and February 2023 with a convenience sample of 20 college students, ages 18–22, attending a public university in the southeastern United States. Qualitative data analysis revealed three main themes. First, most participants conveyed fear, dismay, and anger about the decision in Dobbs v. Jackson Women’s Health Organization to overturn Roe v. Wade and a few expressed concerns about potential restrictions on contraception. …

The Impact Of Countries' Leaders' Responses On Covid-19 Deaths, Kate Rumisek

Honors Undergraduate Theses

The COVID-19 pandemic was an unprecedented health crisis with consequences felt worldwide. While every country was impacted, each leader had a different response resulting in different consequences per nation. This paper evaluates the responses of three countries' leaders to the COVID-19 pandemic in relation to COVID-19-related deaths. The countries analyzed are New Zealand, Brazil, and the United States. New Zealand's Prime Minister's response was characterized as proactive and strict. Under the leadership of Bolsonaro, Brazil ignored the magnitude of the pandemic, leading to a lack of a cohesive national plan. The United States, led by President Trump, responded with a …

A Rapid, Low-Cost, And Highly Sensitive Sars-Cov-2 Diagnostic Based On Whole-Genome Sequencing, Per A Adastra, Neva C Durand, Namita Mitra, Saul Godinez Pulido, Ragini Mahajan, Alyssa Blackburn, Zane L Colaric, Joshua W M Theisen, David Weisz, Olga Dudchenko, Andreas Gnirke, Suhas S P Rao, Parwinder Kaur, Erez Lieberman Aiden, Aviva Presser Aiden

Faculty, Staff and Students Publications

Early detection of SARS-CoV-2 infection is key to managing the current global pandemic, as evidence shows the virus is most contagious on or before symptom onset. Here, we introduce a low-cost, high-throughput method for diagnosing and studying SARS-CoV-2 infection. Dubbed Pathogen-Oriented Low-Cost Assembly & Re-Sequencing (POLAR), this method amplifies the entirety of the SARS-CoV-2 genome. This contrasts with typical RT-PCR-based diagnostic tests, which amplify only a few loci. To achieve this goal, we combine a SARS-CoV-2 enrichment method developed by the ARTIC Network (https://artic.network/) with short-read DNA sequencing and de novo genome assembly. Using this method, we can reliably ( …

Dietary Behaviours During Covid-19 Among Households At Risk For Food Insecurity, Maha Almohamad, Allison Marshall, Jayna Markand Dave, Ru-Jye Chuang, Christine Markham, Shreela Sharma

Faculty, Staff and Student Publications

The objective of the present study was to examine associations between variables of COVID-19-related concerns and changes in fruit and vegetable (FV) consumption among a sample of participants from the Brighter Bites program at risk for food insecurity. Cross-sectional data were collected during April-June 2020 using a rapid-response survey to understand social needs, COVID-19-related concerns and diet-related behaviours among families with children participating in Brighter Bites (

Cannabis Use Disorder, Suicide Attempts, And Self-Harm Among Adolescents: A National Inpatient Study Across The United States, Adeolu Funso Oladunjoye, Elijah Li, Kammarauche Aneni, Edore Onigu-Otite

Faculty, Staff and Students Publications

Background: Suicide is among the top three causes of adolescent mortality. There is a scarcity of research examining cannabis use and suicidal behavior in adolescents.

Objectives: To determine the association between cannabis use disorder (CUD) and suicide attempt/self-harm in a hospitalized sample of adolescents.

Methods: We conducted a cross-sectional observation study using data from the Nationwide Inpatient Sample collected over four years from January 1, 2016, through December 31, 2019. We included adolescents aged 10-19 hospitalized during the above period (N = 807,105). The primary outcome was suicide attempt/self-harm and the main predictor was CUD. The International Classification of Diseases …

Family Caregiving Of The Elderly In The U.S. And Nepal, Barsha Kharel

All Graduate Theses, Dissertations, and Other Capstone Projects

In an aging society, family caregiving is becoming an increasingly important topic. Elderly adults often rely on their family members as the primary source of support as they age. This paper presents a systematic literature review of family caregiving practices for the elderly in the U.S. and Nepal. The aim is to explore the differences and similarities between the two countries in terms of family caregiving practices for the elderly. The review includes five initial literature sources and identifies two common themes: first, both societies consider family as the main source of support for the elderly, and secondly, elderly people …

Proprietary Trading And Certain Interests In And Relationships With Covered Funds, United States: Federal Deposit Insurance Corporation (Fdic)

Documents

No abstract provided.