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Legitimacy At Sea: Expanding Considerations Of Sea Control, Ian Birdwell Oct 2024

Legitimacy At Sea: Expanding Considerations Of Sea Control, Ian Birdwell

Graduate Program in International Studies Theses & Dissertations

Sea control has been marketed and accepted as a norm within the global commons, with a variety of states arguing for their visions of control to be viewed as legitimate. As a piece of the global commons, sea lanes are a critical enabler for the global economy and possess significant military and political significance, yet the literature revolving around ideas of sea control treats it as a military achievement at the end of a campaign and remains focused on naval power as the key mechanism for state involvement. What best explains the mechanism states use to achieve sea control, especially …


Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022, Alpha Oumar Diallo, Mary E Wikswo, Iddrisu Sulemana, Leila C Sahni, Julie A Boom, Sasirekha Ramani, Rangaraj Selvarangan, Mary E Moffatt, Christopher J Harrison, Natasha Halasa, James Chappell, Laura Stewart, Mary Allen Staat, Elizabeth Schlaudecker, Christina Quigley, Eileen J Klein, Janet A Englund, Danielle M Zerr, Geoffrey A Weinberg, Peter G Szilagyi, Christina Albertin, Samantha H Johnston, John V Williams, Marian G Michaels, Robert W Hickey, Aaron T Curns, Michelle Honeywood, Slavica Mijatovic-Rustempasic, Mathew D Esona, Michael D Bowen, Umesh D Parashar, Rashi Gautam, Sara A Mirza, Jacqueline E Tate Oct 2024

Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022, Alpha Oumar Diallo, Mary E Wikswo, Iddrisu Sulemana, Leila C Sahni, Julie A Boom, Sasirekha Ramani, Rangaraj Selvarangan, Mary E Moffatt, Christopher J Harrison, Natasha Halasa, James Chappell, Laura Stewart, Mary Allen Staat, Elizabeth Schlaudecker, Christina Quigley, Eileen J Klein, Janet A Englund, Danielle M Zerr, Geoffrey A Weinberg, Peter G Szilagyi, Christina Albertin, Samantha H Johnston, John V Williams, Marian G Michaels, Robert W Hickey, Aaron T Curns, Michelle Honeywood, Slavica Mijatovic-Rustempasic, Mathew D Esona, Michael D Bowen, Umesh D Parashar, Rashi Gautam, Sara A Mirza, Jacqueline E Tate

Faculty, Staff and Students Publications

Background: Rotavirus was the leading cause of acute gastroenteritis among US children until vaccine introduction in 2006, after which, substantial declines in severe rotavirus disease occurred. We evaluated rotavirus vaccine effectiveness (VE) over 13 years (2009-2022).

Methods: We analyzed data from the New Vaccine Surveillance Network using a test-negative case-control design to estimate rotavirus VE against laboratory-confirmed rotavirus infections among children seeking care for acute gastroenteritis (≥3 diarrhea or ≥1 vomiting episodes within 24 hours) in the emergency department (ED) or hospital. Case-patients and control-patients were children whose stool specimens tested rotavirus positive or negative, respectively, by enzyme immunoassay or …


Racial Equity, Diversity And Inclusion In Bioethics: Recommendations From The Association Of Bioethics Program Directors Presidential Task Force, Sandra Soo-Jin Lee, Alexis Walker, Shawneequa L Callier, Faith E Fletcher, Charlene Galarneau, Nanibaa' Garrison, Jennifer E James, Renee Mcleod-Sordjan, Ubaka Ogbogu, Nneka Sederstrom, Patrick T Smith, Clarence H Braddock, Christine Mitchell Oct 2024

Racial Equity, Diversity And Inclusion In Bioethics: Recommendations From The Association Of Bioethics Program Directors Presidential Task Force, Sandra Soo-Jin Lee, Alexis Walker, Shawneequa L Callier, Faith E Fletcher, Charlene Galarneau, Nanibaa' Garrison, Jennifer E James, Renee Mcleod-Sordjan, Ubaka Ogbogu, Nneka Sederstrom, Patrick T Smith, Clarence H Braddock, Christine Mitchell

Center for Medical Ethics and Health Policy Staff Publications

Recent calls to address racism in bioethics reflect a sense of urgency to mitigate the lethal effects of a lack of action. While the field was catalyzed largely in response to pivotal events deeply rooted in racism and other structures of oppression embedded in research and health care, it has failed to center racial justice in its scholarship, pedagogy, advocacy, and practice, and neglected to integrate anti-racism as a central consideration. Academic bioethics programs play a key role in determining the field's norms and practices, including methodologies, funding priorities, and professional networks that bear on equity, inclusion, and epistemic justice. …


Racial Equity, Diversity And Inclusion In Bioethics: Recommendations From The Association Of Bioethics Program Directors Presidential Task Force, Sandra Soo-Jin Lee, Alexis Walker, Shawneequa L Callier, Faith E Fletcher, Charlene Galarneau, Nanibaa' Garrison, Jennifer E James, Renee Mcleod-Sordjan, Ubaka Ogbogu, Nneka Sederstrom, Patrick T Smith, Clarence H Braddock, Christine Mitchell Oct 2024

Racial Equity, Diversity And Inclusion In Bioethics: Recommendations From The Association Of Bioethics Program Directors Presidential Task Force, Sandra Soo-Jin Lee, Alexis Walker, Shawneequa L Callier, Faith E Fletcher, Charlene Galarneau, Nanibaa' Garrison, Jennifer E James, Renee Mcleod-Sordjan, Ubaka Ogbogu, Nneka Sederstrom, Patrick T Smith, Clarence H Braddock, Christine Mitchell

Center for Medical Ethics and Health Policy Staff Publications

Recent calls to address racism in bioethics reflect a sense of urgency to mitigate the lethal effects of a lack of action. While the field was catalyzed largely in response to pivotal events deeply rooted in racism and other structures of oppression embedded in research and health care, it has failed to center racial justice in its scholarship, pedagogy, advocacy, and practice, and neglected to integrate anti-racism as a central consideration. Academic bioethics programs play a key role in determining the field's norms and practices, including methodologies, funding priorities, and professional networks that bear on equity, inclusion, and epistemic justice. …


Burden Of Mortality From Hepatocellular Carcinoma And Biliary Tract Cancers By Race And Ethnicity And Sex In Us, 2018–2023, Donghee Kim, Richie Manikat, Karn Wijarnpreecha, George Cholankeril, Aijaz Ahmed Oct 2024

Burden Of Mortality From Hepatocellular Carcinoma And Biliary Tract Cancers By Race And Ethnicity And Sex In Us, 2018–2023, Donghee Kim, Richie Manikat, Karn Wijarnpreecha, George Cholankeril, Aijaz Ahmed

Faculty, Staff and Students Publications

BACKGROUNDS/AIMS: The trends in mortality of hepatocellular carcinoma (HCC) and biliary tract cancers stratified by sex and race/ethnicity in the US continue to evolve. We estimated the sex- and race/ethnicity-based trends in HCC and biliary tract cancers-related mortality in US adults with a focus on disease burden.

METHODS: We performed a population-based analysis using the US national mortality records from 2018 to 2023. We identified HCC and biliary tract cancer using appropriate ICD-10 codes. Temporal trends in mortality were calculated by joinpoint analysis with annual percentage change (APC).

RESULTS: Annual age-standardized mortality from HCC decreased steadily with an APC of …


Treatment Of Acute Myeloid Leukemia In The Community Setting, Taha Al-Juhaishi, Servillano Dela Cruz, Rohan Gupta, Gina Keiffer, Vicki Morrison, Iuliana Shapira, Ashley Woods, Kelly Norsworthy, Romeo Angelo De Claro, Marc Theoret, Ravin Garg, Elizabeth Dianne Pulte Sep 2024

Treatment Of Acute Myeloid Leukemia In The Community Setting, Taha Al-Juhaishi, Servillano Dela Cruz, Rohan Gupta, Gina Keiffer, Vicki Morrison, Iuliana Shapira, Ashley Woods, Kelly Norsworthy, Romeo Angelo De Claro, Marc Theoret, Ravin Garg, Elizabeth Dianne Pulte

Kimmel Cancer Center Faculty Papers

The treatment landscape for acute myeloid leukemia (AML) is rapidly changing. Many new agents and lower-intensity regimens have been approved and can be safely used by hematologists and oncologists in both academic and community settings. The US Food and Drug Administration (FDA) held a virtual symposium on AML treatment in the community in November 2022. Several members of the FDA, along with practicing hematologists and oncologists in both academic and community settings, participated in the symposium. The goal of the symposium was to discuss challenges and opportunities in the treatment of patients with AML in community oncology settings. A summary …


Exoskeletal-Assisted Walking In Veterans With Paralysis: A Randomized Clinical Trial, Ann M Spungen, Ellen J Dematt, Kousick Biswas, Karen M Jones, Zhibao Mi, Amanda J Snodgrass, Kel Morin, Pierre K Asselin, Christopher M Cirnigliaro, Steven Kirshblum, Peter H Gorman, Lance L Goetz, Katherine Stenson, Kevin T White, Alice Hon, Sunil Sabharwal, B Jenny Kiratli, Doug Ota, Bridget Bennett, Joseph E Berman, Denis Castillo, Kenneth K Lee, Byron W Eddy, M Kristi Henzel, Michelle Trbovich, Sally A Holmes, Felicia Skelton, Michael Priebe, Stephen L Kornfeld, Grant D Huang, William A Bauman Sep 2024

Exoskeletal-Assisted Walking In Veterans With Paralysis: A Randomized Clinical Trial, Ann M Spungen, Ellen J Dematt, Kousick Biswas, Karen M Jones, Zhibao Mi, Amanda J Snodgrass, Kel Morin, Pierre K Asselin, Christopher M Cirnigliaro, Steven Kirshblum, Peter H Gorman, Lance L Goetz, Katherine Stenson, Kevin T White, Alice Hon, Sunil Sabharwal, B Jenny Kiratli, Doug Ota, Bridget Bennett, Joseph E Berman, Denis Castillo, Kenneth K Lee, Byron W Eddy, M Kristi Henzel, Michelle Trbovich, Sally A Holmes, Felicia Skelton, Michael Priebe, Stephen L Kornfeld, Grant D Huang, William A Bauman

Faculty, Staff and Students Publications

IMPORTANCE: Robotic exoskeletons leverage technology that assists people with spinal cord injury (SCI) to walk. The efficacy of home and community exoskeletal use has not been studied in a randomized clinical trial (RCT).

OBJECTIVE: To examine whether use of a wheelchair plus an exoskeleton compared with use of only a wheelchair led to clinically meaningful net improvements in patient-reported outcomes for mental and physical health.

DESIGN, SETTING, AND PARTICIPANTS: This RCT of veterans with SCI was conducted at 15 Veterans Affairs medical centers in the US from September 6, 2016, to September 27, 2021. Data analysis was performed from March …


Major Political Events From The 1960s To The 2020s: An Analytical Perspective, Yun Song Sep 2024

Major Political Events From The 1960s To The 2020s: An Analytical Perspective, Yun Song

Multicultural Center Publications

This research paper provides a comprehensive analysis of major political events in the United States from the 1960s to the 2020s. It examines key presidential elections and significant political incidents, exploring their impact on the political landscape and their contributions to the evolution of American governance and society. The study delves into the interplay between media, social movements, economic conditions, and political strategies, highlighting how these factors have shaped electoral outcomes and policy decisions over the decades.


Home Ownership Inaccessibility For Upcoming Generations In The United States, Kendall A. Isom Sep 2024

Home Ownership Inaccessibility For Upcoming Generations In The United States, Kendall A. Isom

Ballard Brief

Affording adequate shelter is an important human need, but it is also a significant aspect of the American Dream to be able to own a home. Housing inaccessibility poses a significant challenge for younger generations in America, including Millennials and Generation Z, compared to their parent and grandparent generations such as Baby Boomers and Generation X. This challenge is primarily driven by contributing factors such as wage stagnation, an increased cost of living, and a housing shortage. These factors collectively contribute to consequences including younger individuals being unable to afford homes, exacerbating wealth inequality, and hindering one’s ability to retire …


Commentary: No One Wants An Asian Nato, Except Japan’S New Pm Ishiba, Benjamin Ho, William A. Callahan Sep 2024

Commentary: No One Wants An Asian Nato, Except Japan’S New Pm Ishiba, Benjamin Ho, William A. Callahan

Research Collection School of Social Sciences

In a joint commentary, SMU Professor of Political Science William A Callahan discussed the reluctance of Southeast Asian nations, excluding Japan under its new Prime Minister Shigeru Ishiba, to embrace a collective defense system aimed at countering China. They explained why Mr Ishiba's proposal for an Asian North Atlantic Treaty Organization (NATO) would benefit Japan, how it works in Europe, and why it is unlikely to gain strong support in Southeast Asia.


Barriers And Facilitators To Administering Burn Pit Registry Exams In Vha Facilities, Patricia V Chen, Israel C Christie, Kyler M Godwin, Jaehwan Han, Nisha Jani, Anays Sotolongo, Asma Ali, Drew A Helmer Aug 2024

Barriers And Facilitators To Administering Burn Pit Registry Exams In Vha Facilities, Patricia V Chen, Israel C Christie, Kyler M Godwin, Jaehwan Han, Nisha Jani, Anays Sotolongo, Asma Ali, Drew A Helmer

Faculty and Staff Publications

Introduction: The Veterans Health Administration (VHA) established the Airborne Hazards and Open Burn Pit Registry (AHOBPR) in 2014 to address exposure concerns for veterans who have served in military operations in Southwest Asia and Afghanistan. By 2021, over 236,086 veterans completed the online questionnaire and 60% requested an AHOBPR examination. Of those requesting an exam, only 12% had an exam recorded in their medical record. This article summarizes barriers and facilitators to delivering AHOBPR exams and shares lessons learned from facilities who have successfully implemented burn pit exams for veterans.

Materials and methods: We (I.C.C and J.H.) constructed a key …


The Phenomenological Effects Of Fidel Castro’S Communist Revolution On The Christian Church In Cuba, Daniel Orama Aug 2024

The Phenomenological Effects Of Fidel Castro’S Communist Revolution On The Christian Church In Cuba, Daniel Orama

Masters Theses

The claims that religious freedom in Cuba can coexist alongside the Communist, Marxist, Socialist regime without hindrance contradicts the Word of God and eyewitness testimonies of those who serve in the Cuban Christian church. Church pastors in Cuba often suffer imprisonment as long as twenty years before being allowed to return to their homes and communities. This study regains the views of countless pastors and those serving in churches throughout Cuba, whose opinions concerning Christians who put themselves in harm’s way against the communist authorities are expurgated. Using the qualitative research paradigm, this study utilizes qualitative artistic and creative research …


Who Lives Where: A Comprehensive Population Taxonomy Of Cities, Suburbs, Exurbs, And Rural Areas In The United States, Brian Edward Johnson, Jason Shifferd Aug 2024

Who Lives Where: A Comprehensive Population Taxonomy Of Cities, Suburbs, Exurbs, And Rural Areas In The United States, Brian Edward Johnson, Jason Shifferd

The Geographical Bulletin

This paper answers the question: how many Americans live in cities, suburbs, exurbs, and rural areas in the United States? Previous works have examined only one or some of these settlement types instead of accounting for the entire country’s population, or have employed highly technical classifications uncommon in common parlance. T his paper develops a comprehensive classification scheme using vernacular settlement types, then organizes U.S. Census data into the taxonomy presented here. This research contributes to the existing literature by (1) reporting the number and percentages living in all four major settlement types rather than covering only one or two …


Disparities In Exposure To Tobacco On Television Or Streaming Platforms, Henry K Onyeaka, Onyema G Chido-Amajuoyi, Itunu Sokale, Kobi V Ajayi, A Eden Evins, Hermioni L Amonoo, Sanjay Shete Aug 2024

Disparities In Exposure To Tobacco On Television Or Streaming Platforms, Henry K Onyeaka, Onyema G Chido-Amajuoyi, Itunu Sokale, Kobi V Ajayi, A Eden Evins, Hermioni L Amonoo, Sanjay Shete

Faculty, Staff and Student Publications

Importance: With the rise in popularity of streaming platforms concerns about exposure to tobacco advertising and promotion have emerged. While tobacco marketing and promotion through traditional television (TV) media channels has been extensively studied, less is known about exposure to tobacco through TV or streaming platforms and its associated factors.

Objective: To examine the prevalence and factors associated with exposure to tobacco products advertised, marketed, or promoted on TV or streaming platforms among US adults.

Design, setting, and participants: This cross-sectional study used data from the National Cancer Institute's Health Information National Trends Survey (HINTS 6), conducted from March 7 …


Patriots Or Rebels: Ethical Debate Behind The American Revolution, Nicolette Falvo Jul 2024

Patriots Or Rebels: Ethical Debate Behind The American Revolution, Nicolette Falvo

History Department Theses

This paper, "Patriots or Rebels: Ethical Debate Behind the American Revolution," critically examines the justification and historical significance of the American Revolution. It argues that the motivations behind the revolutionary war and the colonists' outrage against British policies were complex and multifaceted, prompting scrutiny of the legitimacy of their actions. Central to this analysis is the colonists' deliberate choice to establish a democratic republic, diverging from the English monarchy, and an evaluation of the contemporary state of American governance. Drawing on Gordon S. Wood's "The Radicalism of the American Revolution," which highlights its transformative impact on American society and political …


A Mini-Review Of Strategies For Recruiting Older African Americans To Alzheimer's Disease Research., Darlingtina Esiaka, Christina C Yarborough, Bernadette A Fausto, Mark A Gluck Jul 2024

A Mini-Review Of Strategies For Recruiting Older African Americans To Alzheimer's Disease Research., Darlingtina Esiaka, Christina C Yarborough, Bernadette A Fausto, Mark A Gluck

Behavioral Science Faculty Publications

African Americans experience higher incidence and prevalence of Alzheimer's disease (AD). Yet, they continue to be underrepresented in AD research, limiting the ability to generalize findings to the increasingly diverse US population. To reduce AD disparities, targeted efforts are needed to increase the representation of African Americans in AD research. This mini review identified evidence-based strategies that increased research participation among older African Americans. Four recruitment strategies emerged from eight published peer-reviewed studies that directly evaluated the effectiveness of strategies aimed at increasing the number of African American participants in Alzheimer's research. The strategies include community outreach and education, face-to-face …


Kaleidoscopic Federalism, Roger Karapin Jul 2024

Kaleidoscopic Federalism, Roger Karapin

Publications and Research

This chapter focuses on state-level climate policies in the United States in the context of its federalist system. The empirical focus is on policies that have been adopted by many states and that have been most effective in reducing greenhouse gas (GHG) emissions, which include target setting, emissions trading, and sectoral policies on renewable energy, motor vehicles, appliances, and power plants (Karapin 2016; Karapin/Vogel 2024: ch. 1). It addresses five questions: First, what are the most important policies that state governments have adopted over the last few decades? Second, how have those efforts tied in with federal policies in the …


Crisis In The Classroom: The Rise Of Book Bans Threatening American Youth, Kris Barrios Jun 2024

Crisis In The Classroom: The Rise Of Book Bans Threatening American Youth, Kris Barrios

Florida Atlantic University Undergraduate Law Journal

Inspired by the experiences of his father as a Polish Jew during the reign of Adolf Hitler, author Art Spiegelman wrote Maus to memorialize the lives of Holocaust survivors. However, multiple state governments have attempted to limit American youth’s access to Maus and other classic literature by pulling books from classroom shelves.1 According to PEN America, over 5,000 books have been banned in the United States in the last two years, with more than half of these bans targeting young adult literature.2 The most commonly objected themes in these books were depictions of violence, the discussion of racism, and the …


The Psychological Risks Of War Between The United States And China, Eugen Koh Jun 2024

The Psychological Risks Of War Between The United States And China, Eugen Koh

New England Journal of Public Policy

The relationship between the United States and China has deteriorated over the past two decades and fears of escalating risks of war are regularly reported in global media. This article explores the psychological factors that contribute to the two superpowers shifting from a collaborative relationship to a competitive relationship, seeing each other as enemies, feeling increasingly threatened by each other, failing to consider the heightened sensitivities that arise from their respective traumatic pasts, triggering the collapse of thinking and unleashing of uncontainable emotionality, escalating accidents to conflict, and escalating conflict to war. It highlights the dangers of ignoring heightened trauma-related …


Romani American History: Historical Absences And Their Consequences, Ann Ostendorf Jun 2024

Romani American History: Historical Absences And Their Consequences, Ann Ostendorf

History Faculty Scholarship

American historians have created an historical absence by ignoring Romani people’s presence in evidence from the past. The origins of this “absence-ing” are multifaceted and interrelated, but fundamentally stem from the continued influence of out-of-date and unprofessional ways of thinking and knowing. Examining and understanding “absence-ing” requires a consideration of the nature of the discipline of history as well as a history of the missing historicization of Romani Americans. The consequences of the “absence-ing” of Romani people from American histories have negatively and distinctively influenced four different groups of people: historians of the Americas; historians of Romani people in Europe; …


Exploring How Sino-Business Culture Informs United States Business Negotiation Practice, Chase Peterson Jun 2024

Exploring How Sino-Business Culture Informs United States Business Negotiation Practice, Chase Peterson

Undergraduate Honors Theses

Numerous scholarly works have explored the intricacies of negotiating with China. This paper aims to add value to previous research by providing insights deduced from cross-cultural communication with individuals from the People's Republic of China (PRC), while emphasizing the advantages of adaptation of Chinese business culture by U.S. negotiators. The United States Institute of Peace observed several biases among U.S. negotiators including a tendency to accept initial solutions prematurely, as well as a lack of understanding regarding counterparts' objectives and contextual circumstances (Quinney 2002). The strengths of Chinese business culture help remedy these tendencies and inform Western negotiators how different …


Investor Presentation: May 2024, Fhlb Office Of Finance Jun 2024

Investor Presentation: May 2024, Fhlb Office Of Finance

Documents

No abstract provided.


Closure Of Dialysis Clinics In The United States In 2021-2023, Kamyar Kalantar-Zadeh, Dawn P Edwards, David Henner, Daniel L Landry, Donald A Molony, Preethi Yerram, On Behalf Of The Medical Advisory Council Of The National Forum Of Esrd Networks Jun 2024

Closure Of Dialysis Clinics In The United States In 2021-2023, Kamyar Kalantar-Zadeh, Dawn P Edwards, David Henner, Daniel L Landry, Donald A Molony, Preethi Yerram, On Behalf Of The Medical Advisory Council Of The National Forum Of Esrd Networks

Faculty, Staff and Student Publications

No abstract provided.


Racial And Ethnic Disparities In Cardiovascular Disease – Analysis Across Major Us National Databases, Abdul Mannan Khan Minhas, Khawaja M Talha, Dmitry Abramov, Heather M Johnson, Steve Antoine, Fatima Rodriguez, Marat Fudim, Erin D Michos, Arunima Misra, Layla Abushamat, Vijay Nambi, Gregg C Fonarow, Christie M Ballantyne, Salim S Virani Jun 2024

Racial And Ethnic Disparities In Cardiovascular Disease – Analysis Across Major Us National Databases, Abdul Mannan Khan Minhas, Khawaja M Talha, Dmitry Abramov, Heather M Johnson, Steve Antoine, Fatima Rodriguez, Marat Fudim, Erin D Michos, Arunima Misra, Layla Abushamat, Vijay Nambi, Gregg C Fonarow, Christie M Ballantyne, Salim S Virani

Faculty, Staff and Students Publications

Background: There are several studies that have analyzed disparities in cardiovascular disease (CVD) health using a variety of different administrative databases; however, a unified analysis of major databases does not exist. In this analysis of multiple publicly available datasets, we sought to examine racial and ethnic disparities in different aspects of CVD, CVD-related risk factors, CVD-related morbidity and mortality, and CVD trainee representation in the US.

Methods: We used National Health and Nutrition Examination Survey, National Ambulatory Medical Care Survey, National Inpatient Sample, Centers for Disease Control and Prevention Wide-Ranging OnLine Data for Epidemiologic Research, United Network for Organ Sharing, …


Phase Ii Study Of Ulixertinib In Children And Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Alterations: Apec1621j Of The National Cancer Institute-Children's Oncology Group Pediatric Match Trial, Kieuhoa T Vo, Amit J Sabnis, P Mickey Williams, Sinchita Roy-Chowdhuri, David R Patton, Brent Coffey, Joel M Reid, Jin Piao, Lauren Saguilig, Todd A Alonzo, Stacey L Berg, Alok Jaju, Elizabeth Fox, Brenda J Weigel, Douglas S Hawkins, Margaret M Mooney, Naoko Takebe, James V Tricoli, Katherine A Janeway, Nita L Seibel, D Williams Parsons Jun 2024

Phase Ii Study Of Ulixertinib In Children And Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Alterations: Apec1621j Of The National Cancer Institute-Children's Oncology Group Pediatric Match Trial, Kieuhoa T Vo, Amit J Sabnis, P Mickey Williams, Sinchita Roy-Chowdhuri, David R Patton, Brent Coffey, Joel M Reid, Jin Piao, Lauren Saguilig, Todd A Alonzo, Stacey L Berg, Alok Jaju, Elizabeth Fox, Brenda J Weigel, Douglas S Hawkins, Margaret M Mooney, Naoko Takebe, James V Tricoli, Katherine A Janeway, Nita L Seibel, D Williams Parsons

Center for Medical Ethics and Health Policy Staff Publications

Purpose: The National Cancer Institute-Children's Oncology Group (NCI-COG) Pediatric MATCH trial assigns patients age 1-21 years with refractory malignancies to phase II treatment arms of molecularly targeted therapies on the basis of genetic alterations detected in their tumor. Patients with activating alterations in the mitogen-activated protein kinase pathway were treated with ulixertinib, an extracellular signal-regulated kinase (ERK)1/2 inhibitor.

Methods: As there were no previous pediatric data, ulixertinib was initially tested in a dose escalation cohort to establish the recommended phase II dose (RP2D) before proceeding to the phase II cohort. Ulixertinib was administered at 260 mg/m2/dose orally twice a day …


Life-Space Mobility, Transportation, And The Companionship Network Of Members Of A Hispanic Senior Center, Rebecca L Mauldin, Rupal Parekh, John P Connolly, Stephen P Mattingly, Aiman Mushtaq, Kayo Fujimoto Jun 2024

Life-Space Mobility, Transportation, And The Companionship Network Of Members Of A Hispanic Senior Center, Rebecca L Mauldin, Rupal Parekh, John P Connolly, Stephen P Mattingly, Aiman Mushtaq, Kayo Fujimoto

Faculty, Staff and Student Publications

Objectives: Companions (i.e., friends who spend time together) are important for the well-being of older adults. Senior centers in the United States are places for older adults to participate in group activities and form and maintain companionships. However, differences in mobility and transportation may affect the ability of older adults to leverage senior center activities into actual companionships.

Methods: This social network analysis was conducted to characterize the companionship network among members of a senior center in relation to their life-space mobility and transportation resources. An exponential random graph model was estimated to identify mobility- and transportation-related correlates of the …


Authenticating Social Media Evidence In Chinese Criminal Procedure Law -- A Comparative Study, Yage Huang May 2024

Authenticating Social Media Evidence In Chinese Criminal Procedure Law -- A Comparative Study, Yage Huang

Maurer Theses and Dissertations

Authentication requires the proponent to provide sufficient proof that the proposed social media evidence is, indeed, what it is claimed to be. The rapid proliferation of social media evidence has posed significant challenges for its authentication. This dissertation explores the authentication challenges for social media evidence in a comprehensive manner.

This research employs a qualitative research methodology, including theoretical and analytical methods, to examine the theoretical approaches, statutory provisions, and recent judicial rulings related to the authentication of social media evidence within the legal frameworks of China and the United States. Through a comparative analysis, this study reveals significant commonalities …


Profiles In Influence: Shaping American Perceptions, Attitudes, And Policy Towards China, Benjamin Merritt May 2024

Profiles In Influence: Shaping American Perceptions, Attitudes, And Policy Towards China, Benjamin Merritt

Masters Theses

Pearl Buck, Henry Luce, Edgar Snow, and Richard Nixon have profoundly influenced Sino-American relations throughout the 20th century. Their impact on American perceptions, attitudes, and foreign policy has played a pivotal role in shaping the current state of relations between the United States government and the People’s Republic of China. Pivotal historical events such as WWI & WWII, the Sino-Japanese War, China’s Civil War, and the Soviet-Sino conflict—among other events—have also significantly influenced the dynamics of Sino-American relations. Despite their importance, there is a notable absence of studies that comprehensively explore the collective impact of these individuals and events. Understanding …


Cultural Hybridization In The United States: The Case Of Chicanos/Mexican-American Music, Jeffrey R. Craig May 2024

Cultural Hybridization In The United States: The Case Of Chicanos/Mexican-American Music, Jeffrey R. Craig

Senior Theses

How do immigrant communities in the United States maintain aspects of their culture when they have to navigate between an American culture and their own? This study will center Chicanos, who fit this description by being Mexicans who have to navigate between having roots in Mexico and a new cultural environment in America. More specifically, an analysis of corrido music (and their corresponding music videos) produced by a Chicano band in the 21st century will be important to understanding how a hybrid identity is communicated through that medium. Lyrics, Slang, Styles of Dress, Instruments and Rhythms will be used as …


The Legal Nature Of Cyberbullying: A Comparative Study Between The American And The Jordanian Laws, Alaeldin Mansour Maghaireh Dr. May 2024

The Legal Nature Of Cyberbullying: A Comparative Study Between The American And The Jordanian Laws, Alaeldin Mansour Maghaireh Dr.

UAEU Law Journal

The research is aimed to highlight the emerging phenomenon of cyberbullying in Jordan by analysing some of the main legal aspects of cyberbullying and relevant laws. It analysed whether the nature of the phenomenon constitutes a crime, and therefore, must be explicitly stated in the relevant laws, or it is only a bad social phenomenon that can be addressed within the school environment, and therefore no need for legislative provisions to prohibit it. The research showed the gravity of the psychological and physical effects of cyberbullying and its diversity forms and methods. Also, it underscored the paucity of the legal …