Digital Commons Network^™

A Protocol For A Cluster Randomized Trial Of Care Delivery Models To Improve The Quality Of Smoking Cessation And Shared Decision Making For Lung Cancer Screening, Lisa M Lowenstein, Ya-Chen Tina Shih, Jennifer Minnix, Maria A Lopez-Olivo, Kristin G Maki, George Kypriotakis, Viola B Leal, Sanjay S Shete, James Fox, Shawn P Nishi, Paul M Cinciripini, Robert J Volk

Faculty, Staff and Student Publications

BACKGROUND: Patients eligible for lung cancer screening (LCS) are those at high risk of lung cancer due to their smoking histories and age. While screening for LCS is effective in lowering lung cancer mortality, primary care providers are challenged to meet beneficiary eligibility for LCS from the Centers for Medicare & Medicaid Services, including a patient counseling and shared decision-making (SDM) visit with the use of patient decision aid(s) prior to screening.

METHODS: We will use an effectiveness-implementation type I hybrid design to: 1) identify effective, scalable smoking cessation counseling and SDM interventions that are consistent with recommendations, can be …

Impacts Of Climate Change In The United States, Nathan Thompson

Ballard Brief

While every country both contributes to and feels the effects of climate change, the United States' heavy influence and high rates of contribution make this problem even more acute domestically. Climate change is primarily driven by human emission of greenhouse gases through the burning of fossil fuels and from mass-scale agriculture. Because climate change can be a polarizing issue, passing legislation to slow the harmful contributing factors has proven difficult. The effects of climate change have worsened in the past few decades, with increased instances of wildfires and extreme shifts in weather patterns. These negative consequences disproportionately affect vulnerable people …

“From An Elephant Into A Ballerina:” The Future Of Higher Education From Senior Leaders At Public Very High Research Institutions, Sarah Cathleen Rice Denison

Graduate Theses and Dissertations

The purpose for conducting the study was to identify how Very High Research university senior leaders at public institutions in the United States described their vision of the future of higher education over the next 25 years. Specifically, the study provided an opportunity for university chancellors and presidents to describe their versions of what the future holds for higher education and how they are preparing for that future. A vision for the future included senior leader’s perspectives on three elements of the university: the university’s mission and purpose, academics, and student services. Their experience in higher education combined with their …

Heterogeneity Of Treatment Effects Of Hydrocortisone By Risk Of Bronchopulmonary Dysplasia Or Death Among Extremely Preterm Infants In The National Institute Of Child Health And Human Development Neonatal Research Network Trial: A Secondary Analysis Of A Randomized Clinical Trial, Samuel J Gentle, Matthew A Rysavy, Lei Li, Matthew M Laughon, Ravi M Patel, Erik A Jensen, Susan Hintz, Namasivayam Ambalavanan, Waldemar A Carlo, Kristi Watterberg, National Institute Of Child Health And Human Development Neonatal Research Network

Faculty, Staff and Student Publications

IMPORTANCE: Extremely preterm infants who develop bronchopulmonary dysplasia (BPD) are at a higher risk for adverse pulmonary and neurodevelopmental outcomes. In the National Institute of Child Health and Human Development Neonatal Research Network (NICHD NRN) Hydrocortisone Trial, hydrocortisone neither reduced rates of BPD or death nor increased rates of neurodevelopmental impairment (NDI) or death.

OBJECTIVE: To determine whether estimated risk for grades 2 to 3 BPD or death is associated with the effect of hydrocortisone on the composite outcomes of (1) grades 2 to 3 BPD or death and (2) moderate or severe NDI or death.

DESIGN, SETTING, AND PARTICIPANTS: …

Prevalence And Descriptive Epidemiology Of Turner Syndrome In The United States, 2000-2017: A Report From The National Birth Defects Prevention Network, Bailey A Martin-Giacalone, Angela E Lin, Sonja A Rasmussen, Russell S Kirby, Eirini Nestoridi, Rebecca F Liberman, A J Agopian, John C Carey, Janet D Cragan, Nina Forestieri, Vinita Leedom, Aubree Boyce, Wendy N Nembhard, Monika Piccardi, Theresa Sandidge, Xiaoyi Shan, Charles J Shumate, Erin B Stallings, Roger Stevenson, Philip J Lupo

Faculty, Staff and Students Publications

The lack of United States population-based data on Turner syndrome limits assessments of prevalence and associated characteristics for this sex chromosome abnormality. Therefore, we collated 2000-2017 data from seven birth defects surveillance programs within the National Birth Defects Prevention Network. We estimated the prevalence of karyotype-confirmed Turner syndrome diagnosed within the first year of life. We also calculated the proportion of cases with commonly ascertained birth defects, assessed associations with maternal and infant characteristics using prevalence ratios (PR) with 95% confidence intervals (CI), and estimated survival probability. The prevalence of Turner syndrome of any pregnancy outcome was 3.2 per 10,000 …

Neighborhood-Level Factors Contribute To Disparities In Hepatocellular Carcinoma Incidence In Texas, Abiodun O Oluyomi, Hashem B El-Serag, Adegboyega Olayode, Aaron P Thrift

Faculty, Staff and Students Publications

BACKGROUND AND AIMS: Texas has the highest hepatocellular carcinoma (HCC) incidence rates in the continental United States, but these rates vary by race-ethnicity. We examined racial-ethnic disparities through a geospatial analysis of the social determinants of health.

METHODS: Using data from the Texas Cancer Registry, we assembled 11,547 HCC cases diagnosed between 2011 and 2015 into Texas's census tracts geographic units. Twenty-nine neighborhood measures representing demographics and socioeconomic, and employment domains were retrieved from the U.S. Census Bureau. We performed a series of aspatial and spatially weighted regression models to identify neighborhood-level characteristics associated with HCC risk.

RESULTS: We found …

Internal Review Of The Supervision And Closure Of Signature Bank, New York State Department Of Financial Services (Nys Dfs)

Documents

No abstract provided.

Fdic's Supervision Of Signature Bank, Federal Deposit Insurance Corporation

Documents

No abstract provided.

Bank Regulation: Preliminary Review Of Agency Actions Related To March 2023 Bank Failures, United States: Government Accountability Office (Gao)

Documents

No abstract provided.

A Fake Future: The Threat Of Foreign Disinformation On The U.S. And Its Allies, Brandon M. Rubsamen

Global Tides

This paper attempts to explain the threat that foreign disinformation poses for the United States Intelligence Community and its allies. The paper examines Russian disinformation from both a historical and contemporary context and how its effect on Western democracies may only be exacerbated in light of Chinese involvement and evolving technologies. Fortunately, the paper also studies practices and strategies that the United States Intelligence Community and its allied foreign counterparts may use to respond. It is hoped that this study will help shed further light on Russian and Chinese disinformation campaigns and explain how the Intelligence Community can efficiently react.

Exploring Inmate Health In Prisons: Health Issues, Interventions, And Suggestions To Improve Care, Jenna Healy

Honors Program Theses and Projects

The United States has the highest number of prisoners per capita at 639 people per 100,0008. There has been a fivefold increase in the number of inmates in the United States prison systems since 197044, and this may be a major contributor to the corrections healthcare system having trouble keeping up with this growth compared to the general population of the United States. According to the World Health Organization, the United States has documented higher mortality rates than many other developed countries. Rates of conditions such as cardiovascular disease have decreased everywhere, but much less in the United States. In …

Understanding The Effectiveness Of Russian Influence Operations On The United States As Compared To Other Regimes, Giselle Weiss

National Security Affairs and International Relations Theses

For years, the Russian Federation has effectively used influence operations to advance their global position and interfere with democratic processes like elections throughout the world. This project addresses the question: is the United States more susceptible to Russian influence operations compared to other nations with varied protections for freedom of speech? The Western world may be more vulnerable to disinformation and propaganda because people are unaccustomed to state narratives and vulnerable to targeted operations. The more research is done on this topic, the more people can become aware of the problem and protect themselves from vulnerability. By comparing data about …

First Quarter 2023 Earnings Conference Call April 14, 2023, Eli Reith, The Pnc Financial Services Group

Documents

No abstract provided.

Use Of Integrative, Complementary, And Alternative Medicine In Children With Epilepsy: A Global Scoping Review, Zahra Zhu, Daniela Dluzynski, Nouran Hammad, Deepika Pugalenthi, Sarah A. Walser, Rea Mittal, Debopam Samanta, Melanie L. Brown, Ali A. Asadi-Pooya, Angelina Kakooza-Mwesige, Alberto Spalice, Martina Capponi, Alain Lekoubou, Ashutosh Kumar, Sita Paudel, Paul R. Carney, Gayatra Mainali, Sunil Naik

Department of Neurology Faculty Papers

(1) Background: Epilepsy is one of the most common chronic neurological disorders in childhood. Complementary and alternative medicine (CAM) use is highly prevalent in patients with epilepsy. Despite CAM’s widespread and increasing popularity, its prevalence, forms, perceived benefits, and potential risks in pediatric epilepsy are rarely explored. (2) Methods: We performed a scoping review of the available literature on the use of CAM in pediatric epilepsy. (3) Results: Overall, global cross-sectional studies showed a variable degree of CAM usage among children with epilepsy, ranging from 13 to 44% in prevalence. Popular types of CAMs reported were supplements, cannabis products, aromatherapy, …

Changing Trends In Demographics, Risk Factors, And Clinical Features Of Patients With Infective Endocarditis-Related Stroke, 2005-2015, Mohamed Ridha, Opeolu Adeoye, Et Al.

2020-Current year OA Pubs

BACKGROUND AND OBJECTIVES: There is a rising incidence of infective endocarditis-related stroke (IERS) in the United States attributed to the opioid epidemic. A contemporary epidemiologic description is necessary to understand the impact of the opioid epidemic on clinical characteristics of IERS. We describe and analyze trends in the demographics, risk factors, and clinical features of IERS.

METHODS: This is a retrospective cohort study within a biracial population of 1.3 million in the Greater Cincinnati/Northern Kentucky region. All hospitalized patients with hemorrhagic or ischemic stroke were identified and physician verified from the 2005, 2010, and 2015 calendar years using ICD-9 and …

An Examination Of Measurement Invariance With A Multi-Group Confirmatory Factor Analysis Approach, Ruiqin Gao

Theses and Dissertations

This multiple-manuscript dissertation explored the measurement invariance (MI) testing with multiple-group confirmatory factor analysis (MG-CFA) approach from different perspectives. Study 1 explored MI from a theoretical perspective by conducting a systematic review study on MI practices in education. The findings of this study indicated inconsistency in MI practices and showcased the limitations of the MI practices conducted by researchers in the field of education. Study 2 examined MI from an empirical perspective by implementing a cultural MI test of Strengths and Difficulties Questionnaires for elementary school students in the United States and China. The study provided a step-by-step demonstration of …

Assessing The Gaps And Potential Solutions To Improve Access To Genetic Testing For Autistic Individuals, Nisha Dhiren Pandya

Theses and Dissertations

The prevalence of Autism Spectrum Disorder (ASD) continues to increase. Numerous genetic syndromes increase the risk of ASD. Professional organizations have published guidelines on the genetic testing recommended for Autistic individuals. However, healthcare providers do not unanimously offer genetic testing or refer for a genetics evaluation. Notably, parents of Autistic individuals express interest in learning about genetic testing as an option for their children.

This study aimed to identify gaps to improve access to genetic evaluations for Autistic individuals and their families. A survey was sent to healthcare providers across the United States that currently see Autistic individuals. We expected …

“It Looks Like The Future But Feels Like The Past”: Oral (Hi)Stories Of Appalachia As Covid-19 News Stories, Ashley Reid Mcgraw

Theses and Dissertations

Oral historians have often felt obligated to collect stories during disasters and crises, to preserve recollections of experiences and trauma of those affected. During the onset of COVID-19 in the United States, this surge was certainly present. Appalachia, although its boundaries are contested, has a strong association with oral histories, and thus was the focus of one project in particular: a collaboration with the Blue Ridge Public Radio and the Foxfire Appalachian Heritage Museum to collect, curate, publish, and broadcast oral histories of "local" individuals. But what does it mean to be local, in a region as broad as Appalachia? …

Total Daily Energy Expenditure Has Declined Over The Past Three Decades Due To Declining Basal Expenditure, Not Reduced Activity Expenditure, John R Speakman, Jasper M A De Jong, Srishti Sinha, Klaas R Westerterp, Yosuke Yamada, Hiroyuki Sagayama, Philip N Ainslie, Liam J Anderson, Lenore Arab, Kweku Bedu-Addo, Stephane Blanc, Alberto G Bonomi, Pascal Bovet, Soren Brage, Maciej S Buchowski, Nancy F Butte, Stefan G J A Camps, Jamie A Cooper, Richard Cooper, Sai Krupa Das, Peter S W Davies, Lara R Dugas, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W Fudge, Melanie Gillingham, Santu Ghosh, Annelies H Goris, Michael Gurven, Lewis G Halsey, Catherine Hambly, Hinke H Haisma, Daniel Hoffman, Sumei Hu, Annemiek M Joosen, Jennifer L Kaplan, Peter Katzmarzyk, William E Kraus, Robert F Kushner, William R Leonard, Marie Löf, Corby K Martin, Eric Matsiko, Anine C Medin, Erwin P Meijer, Marian L Neuhouser, Theresa A Nicklas, Robert M Ojiambo, Kirsi H Pietiläinen, Jacob Plange-Rhule, Guy Plasqui, Ross L Prentice, Susan B Racette, David A Raichlen, Eric Ravussin, Leanne M Redman, Susan B Roberts, Michael C Rudolph, Luis B Sardinha, Albertine J Schuit, Analiza M Silva, Eric Stice, Samuel S Urlacher, Giulio Valenti, Ludo M Van Etten, Edgar A Van Mil, Brian M Wood, Jack A Yanovski, Tsukasa Yoshida, Xueying Zhang, Alexia J Murphy-Alford, Cornelia U Loechl, Anura Kurpad, Amy H Luke, Herman Pontzer, Matthew S Rodeheffer, Jennifer Rood, Dale A Schoeller, William W Wong

Faculty, Staff and Student Publications

Obesity is caused by prolonged positive energy balance1,2. Whether reduced energy expenditure stemming from reduced activity levels contributes, is debated3,4. Here we used the IAEA DLW database on energy expenditure of adults in the USA and Europe (n = 4799) to explore patterns in total (TEE: n=4799), basal (BEE: n = 1432) and physical activity energy expenditure (AEE: n = 1432) over time. In both sexes total energy expenditure (TEE) adjusted for body composition and age declined with time, while adjusted AEE increased over time. In males adjusted BEE decreased significantly, but …

The Federal Regulators' Response To Recent Bank Failures: Hearing Before The Committee On Financial Services: U.S. House Of Representatives: One Hundred Eighteenth Congress First Session, United States Government

Documents

No abstract provided.

Recent Bank Failures And The Federal Regulatory Response: Hearing Before The Committee On Banking, Housing, And Urban Affairs: United States Senate: One Hundred Eighteenth Congress First Session On Examining The Recent U.S. Bank Failures And The Federal Regulators' Response, United States Government

Documents

No abstract provided.

Concerning United States Constitutional War Powers, Marcus Armstrong

St. Mary's Law Journal

The United States faces a future in which the possibility of a conventional, great-power conflict is elevated. This is because of a constitutional interpretation that has altered United States constitutional war powers significantly. Specifically, the interpretation gives the president the authority to initiate and escalate war or hostilities unilaterally. In this Article, I reexamine that specific historical interpretation and find it wanting. I then offer a different historical interpretation, drawing upon other contemporary writers as well as upon historical events in order to give a more complete and nuanced understanding of the context in which the early American leaders developed …

Masterchef Contestant To Social Media Influencer: Do Men And Women Differ In Pursuing Prestige?, Jada Thomas, Robert Deaner

Student Summer Scholars Manuscripts

The male show-off hypothesis claims that men are more likely than women to show off their abilities and publicly compete. However, the male show-off hypothesis has yet to be tested in a domain where both men and women are consistently involved, such as cooking. To examine showing off and cooking, we assessed the social media behavior of MasterChef reality program contestants both in the U.S. and Australia. We focused on 98 contestants from MasterChef U.S. (m = 52 & f = 46) and 107 contestants from MasterChef Australia (m = 45 & f = 62). For each contestant, we examined …

“Born For A Storm”: Hard-Right Social Media And Civil Unrest, Daniel Karell, Andrew Linke, Edward Holland, Edward Hendrickson

Geosciences Faculty Publications and Presentations

Does activity on hard-right social media lead to hard-right civil unrest? If so, why? We created a spatial panel dataset comprising hard-right social media use and incidents of unrest across the United States from January 2020 through January 2021. Using spatial regression analyses with core-based statistical area (CBSA) and month fixed effects, we find that greater CBSA-level hard-right social media activity in a given month is associated with an increase in subsequent unrest. The results of robustness checks, placebo tests, alternative analytical approaches, and sensitivity analyses support this finding. To examine why hard-right social media activity predicts unrest, we draw …

Svb Financial Group Announces Proposed Offerings Of Common Stock And Mandatory Convertible Preferred Stock, Svb Financial Group

Documents

No abstract provided.

Molnupiravir And Risk Of Hospital Admission Or Death In Adults With Covid-19: Emulation Of A Randomized Target Trial Using Electronic Health Records, Yan Xie, Benjamin Bowe, Ziyad Al-Aly

2020-Current year OA Pubs

OBJECTIVE: To emulate a randomized target trial to estimate the association between the antiviral drug molnupiravir and hospital admission or death in adults with SARS-CoV-2 infection in the community during the omicron predominant era who were at high risk of progression to severe covid-19.

DESIGN: Emulation of a randomized target trial using electronic health records.

SETTING: US Department of Veterans Affairs.

PARTICIPANTS: 85 998 adults with SARS-CoV-2 infection between 5 January and 30 September 2022 and at least one risk factor for progression to severe covid-19: 7818 participants were eligible for and treated with molnupiravir and 78 180 received no …

College Administrator Experiences: A Phenomenological Study Of Higher Education Leadership In American Prisons, Donavan Bailey

Education Doctorate Dissertations

Higher education for the incarcerated (HEP) is a re-energized phenomenon in the age of criminal justice reform and social change. Following the 2015 Second Chance Pell Grant Experimental Initiative (SCP), which granted select colleges tuition funding for prisoners, HEP grew exponentially. The successes of the SCP laid the groundwork for the 2020 FASFA Simplification Act. In July 2023 the 2020 FSA begins, and all those imprisoned within America may access Pell Grant Funds for higher education. Despite momentous efforts to bring higher education to the incarcerated, HEP grapples with continued challenges and lacks unified, evidence-based competency equal to normative higher …

When Hay Was King: Energy History And Economic Nationalism In The Nineteenth-Century United States, Ariel Ron

History Faculty Publications

Hay was a linchpin of the early industrial energy regime. It was the primary fodder for working horses, who became more rather than less important over the 1800s. Though largely ignored by historians, hay was of comparable value to cotton and wheat in the nineteenth-century United States. The crop’s historiographical invisibility is partly due to its relatively informal and decidedly subglobal production and exchange patterns. Whereas cotton and wheat exports passed through customhouses and institutionalized exchanges that carefully recorded trade volumes, hay was almost never exported and often underwent no market transaction at all, instead being used as an intermediate …

Aapm Medical Physics Practice Guideline 13a: Hdr Brachytherapy, Part A, Susan L Richardson, Ivan M Buzurovic, Gil'ad N Cohen, Wesley S Culberson, Claire Dempsey, Bruce Libby, Christopher S Melhus, Robin A Miller, Daniel J Scanderbeg, Samantha J Simiele

Faculty, Staff and Student Publications

The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the science, education, and professional practice of medical physics. The AAPM has more than 8000 members and is the principal organization of medical physicists in the United States. The AAPM will periodically define new practice guidelines for medical physics practice to help advance the science of medical physics and to improve the quality of service to patients throughout the United States. Existing medical physics practice guidelines (MPPGs) will be reviewed for the purpose of revision or renewal, as appropriate, on their …

Higher Doses Of Tisagenlecleucel Are Associated With Improved Outcomes: A Report From The Pediatric Real-World Car Consortium., Heather E. Stefanski, Anne Eaton, Christina Baggott, Jenna Rossoff, Michael R. Verneris, Snehit Prabhu, Holly L. Pacenta, Christine L. Phillips, Julie-An Talano, Amy Moskop, Steven P. Margossian, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, M Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Vasant Chinnabhandar, A Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz

Manuscripts, Articles, Book Chapters and Other Papers

Remarkable complete response rates have been shown with tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell therapy targeting CD19, in patients up to age 26 years with refractory/relapsed B-cell acute lymphoblastic leukemia; it is US Food and Drug Administration approved for this indication. Currently, patients receive a single dose of tisagenlecleucel across a wide dose range of 0.2 to 5.0 × 106 and 0.1 to 2.5 × 108 CAR T cells per kg for patients ≤50 and >50 kg, respectively. The effect of cell dose on survival and remission is not yet well established. Our primary goal was to determine if …