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Drug Development--Stuck In A State Of Puberty?: Regulatory Reform Of Human Clinical Research To Raise Responsiveness To The Reality Of Human Variability, Michael J. Malinowski

Journal Articles

Scathing critiques of the Food and Drug Administration's (“FDA”) performance by the Government Accountability Office and Institutes of Medicine, a plummet in innovative new drug approvals in spite of significant annual investment increases in biopharmaceutical research and development (“R&D”), and market controversies such as the painkiller Vioxx and the diabetes drug Avandia (both associated with significantly escalated risks of heart attacks and strokes) have raised doubts about the sufficiency of FDA *364 regulation. This Article questions how prescription medicines reach the market and proposes law-policy reforms to enhance the FDA's science standard for human clinical trials and new drug approvals. …

Leaving The Fda Behind: Pharmaceutical Outsourcing And Drug Safety, Chenglin Liu

Faculty Articles

During the 2008 heparin crisis, a tainted blood-thinning drug imported from China caused the deaths of at least eighty people in the United States. However, despite the Food and Drug Administration’s (“FDA”) reactive measures, the American regulatory framework for drug safety remains largely unchanged. Currently, about 80% of active pharmaceutical ingredients, 40% of finished drugs, and 50% of all medical devices used in the United States are imported from over 100 countries. With the growth of product outsourcing, pharmaceutical companies in the United States have stopped manufacturing many essential medicines. Nevertheless, the FDA’s foreign inspections have lagged. It would take …

A Brief Review Of The Monetary Policies In The United States: 1970-2010, Markum L. Reed

Research Papers

The essence of monetary policy consists of the introduction of innovative techniques into the system via economic debate. There is a period of incorporation or absorption of ideas, as well as, a period of readjustment. This paper reviews the key economic models that govern modern monetary policy; these constitute the decision making criteria for the Federal Reserve System. This paper reviews the creation of the Federal Reserve System as well as its operating procedures and how it implements monetary policy. We gain factual knowledge of monetary economic models such as the new Keynesian model and we discuss the importance of …

Dispositions In The Twenty First Century School Library Profession, Sue C. Kimmel, Gail K. Dickinson, Carol A. Doll

STEMPS Faculty Publications

Within the school library profession there is an emerging focus on dispositions, defined as "a tendency to exhibit frequently, consciously, and voluntarily a pattern of behavior that is directed to a broad goal" (Katz, 1993). Directed focus groups of practicing school librarians were asked to articulate their vision for school libraries of the future. Data from these groups informed development of six dispositional continua to guide both school library education and school librarianship in the 21st century. This study clarifies the dispositions needed by school librarians in the future.

Jefferson Alumni Bulletin – Volume 61, Number 1, Winter 2012

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Features:

• The Gift of Time for Patients with Advanced Bile Duct Cancer
• Celiac Disease: Overcoming a Stealth Public Health Menace
• Light Therapy for a Blue Planet and Beyond

"Coming Out Of The Shadows": Dream Act Activism In The Context Of Global Anti-Deportation Activism, Laura Corrunker

Indiana Journal of Global Legal Studies

This Article, based on ethnographic fieldwork with an undocumented, youth-led immigrant rights organization, explores undocumented youth activism in the United States in relation to global anti-deportation movements. The strategies that undocumented youth utilize in their fight for the DREAM Act, a bill that creates provisions for certain undocumented youth to legalize their status, are compared with examples of anti-deportation activism outside the United States. In comparing the DREAM Act movement with anti-deportation movements globally, three points of commonality emerge: (1) leadership of undocumented immigrants; (2) visibility; and (3) measures of "deservingness." This Article argues that comparing examples of immigrant activism …

U.S. Proposal For An Intellectual Property Chapter In The Trans-Pacific Partnership Agreement, Sean M. Flynn, Brook Baker, Margot Kaminski, Jimmy Koo

American University International Law Review

No abstract provided.

The Sopa-Tpp Nexus, Jonathan Band

American University International Law Review

No abstract provided.

A Review Of National Msw Generation Assessments In The United States, David J. Tonjes, Krista L. Greene

Technology & Society Faculty Publications

Municipal solid waste (MSW) is generated in very large quantities (probably, between 200 and 400 million tonnes per year) in the United States (US). MSW is generated at millions of places and there is no one precise, general definition for MSW that is generally applied, despite US Environmental Protection Agency efforts. As an element of both commerce and politics, reporting may be framed towards particular ends. Therefore, the two best known assessments of the quantity of US MSW production differ by approximately 50%. The assessors understand some of the reasons for the differences, but our analysis suggests that there are …

Argumentation And Debate In The Foreign Language Classroom: Russian And American University Students Collaborating Through New Technologies, N. Anthony Brown, Ekaterina V. Talalakina, Irina V. Yakusheva, Dennis L. Eggett

Russian Language Journal

As pressure to articulate clear learning outcomes has increased in recent years, many foreign language departments across the United States have drawn on proficiency guidelines established by the American Council on the Teaching of Foreign Languages (ACTFL) to define expectations of their curricula. Misguided perceptions in the past about the “hardness” of the discipline frequently stemmed from a combination of instructors relying on arbitrary measures rather than nationally recognized standards, and administrators failing to provide financial support needed to carry out proficiency testing.

Trends In The Utilization Of Outpatient Advanced Imaging After The Deficit Reduction Act., David C Levin, Vijay M Rao, Laurence Parker

Department of Radiology Faculty Papers

PURPOSE: After the Deficit Reduction Act (DRA) took effect in 2007, there was concern that private office-based imaging facilities would close, that advanced imaging would shift to less convenient hospital-based facilities, and that access to advanced imaging might be restricted. The aim of this study was to see if these developments occurred during the years after the DRA.

METHODS: Using Medicare data, outpatient CT, MRI, and nuclear medicine trends before and after the DRA were studied. Procedure volumes performed in private offices and hospital outpatient departments (HOPDs) were tabulated separately. Volumes were tracked from 2000 to 2006 (before the DRA) …

Exploring The Multi-Generational Influence Of American Ragtime Music Through The Works Of Charles Ives, William Walton And William Bolcom, Rebecca E. Smith

Theses : Honours

Ragtime music is a style of popular music established in America that came to prominence between the years of 1896 and 1918. It is believed to have its roots in Blackface minstrel shows, it's defining feature, the heavily syncopated rhythm, quickly becoming a stereotype of African-American music. This thesis will explore the multi-generational influence of American Ragtime music on the art-music world through the works of Charles Ives (1874-1954), William Walton (1902-1983), and William Bolcom (1938-). It will timeline the undulating influence of Ragtime music on these subsequent generations of composers, noting in particular the revivals of the 1940's and …

Eae/Ase Recommendations For Image Acquisition And Display Using Three-Dimensional Echocardiography., Roberto M. Lang, Luigi P. Badano, Wendy Tsang, David H. Adams, Eustachio Agricola, Thomas Buck, Francesco F. Faletra, Andreas Franke, Judy Hung, Leopoldo Pérez De Isla, Otto Kamp, Jaroslaw D. Kasprzak, Patrizio Lancellotti, Thomas H. Marwick, Marti L. Mcculloch, Mark J. Monaghan, Petros Nihoyannopoulos, Natesa G. Pandian, Patricia A. Pellikka, Mauro Pepi, David A. Roberson, Stanton K. Shernan, Girish S. Shirali, Lissa Sugeng, Folkert J. Ten Cate, Mani A. Vannan, Jose Luis Zamorano, William A. Zoghbi, American Society Of Echocardiography, European Association Of Echocardiography

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Tropical Medicine Training In The Department Of Defense, Rodney L. Coldren, David Brett-Major, Patrick W. Hickey, Eric Garges, Peter J. Weina, Paula Corrigan, Gerald Quinnan

Journal Articles: Epidemiology

No abstract provided.

Human Trafficking In The United States. Part I. State Of The Knowledge, Anchalee (Joy) Panigabutra-Roberts

University of Nebraska-Lincoln Libraries: Faculty Publications

This article, the first of a two-part series, introduces the topic human trafficking in the United States. Based on the literature review, the author delineates definitions of “human trafficking,” the extent and types of human trafficking in the United States, characteristics of trafficked victims and perpetrators, the human trafficking data reporting system, and examples of cases in the United States and its territories. The goal is to provide an introduction to this topic for library staff to use in their research and instruction services. Part II, to follow, is a survey of United States government web resources on human trafficking …

Responses To The Five Questions, Charles J. Dunlap Jr.

Faculty Scholarship

No abstract provided.

Fundamental Forces Driving United States And International Financial Regulations Reform, Lawrence G. Baxter

Faculty Scholarship

Multiple forces create a systemic crisis of the proportions of the Global Financial Crisis of 2008. Global and domestic financial reform is a difficult and perplexing task, one that is likely to take many years, and one that will surely continue to be shaped by a diverse range of forces. Recent measures remain incomplete and in some cases are even proving to be misdirected. This article considers seven fundamental forces shaping actions on future reform, specifically the (1) long term impact of the Crisis (and all financial crises); (2) increase in the “financialization” of the global economy, seemingly disproportionate to …

Accelerating Anthropogenic Land Surface Change And The Status Of Pleistocene Drumlins In New England, Deborah W. Woodcock, John S. Rogan, Samuel D. Blanchard

Geography

Drumlins are glacially derived landforms that are prominent in the landscape over much of southern New England. We carried out a comprehensive ground-based survey in a three-town study area in eastern Massachusetts with the goals of establishing the extent to drumlins have been altered and assessing the associated environmental consequences and probable driving factors. Results show that many drumlins have been significantly altered through levelling and truncation (creation of steep cut and fill slopes), with projects involving movement of 1-1.5×106 m3 of earth materials not now uncommon. Stormwater and wetlands infractions were documented at all the larger excavation sites and …

Higher Education, Corruption, And Reform, Vincent R. Johnson

Faculty Articles

Educational corruption is a problem in every country, particular at the college and university level. With illustrations drawn from the United States, this article considers what “basic principles” should shape efforts to deter, expose, and penalize corruption in academic institutions. The article then identifies “best practices” that should be followed by colleges and universities aspiring to high standards. The discussion explores the role that ethics codes and ethics education can play in fighting corruption. More specifically, the article addresses what types of substantive rules and systematic procedures are essential parts of effective higher education ethics codes. Mindful of the fact …

Our Sister Republic: Creating Mexico In The Minds Of The American Public And The Role Of The Press, Derek Ystebo

History, Philosophy, and Religious Studies

During the Mexican War, Americans radically transformed their ideas about Mexicans and Mexican-Americans. The Mexican War offered itself up as the first of such interactions between the neighboring republics. The Mexican during the War was met largely with criticism from the American public, a criticism aided by the work of the press. While a vast majority of the presses disparaged the Mexican populace on a variety of subjects, not all papers denigrated the Mexicans as some inferior population in need of assistance from the United States in order to survive and reach a proper level of civilization. Papers such as …

To Veil Or Not To Veil : That Is Not The Question ; A Comparative Analysis Of The Implicit Assumptions Driving Veiling Discourse, Erin E. Barta

Undergraduate Theses and Senior Projects

No abstract provided.

A Paradigm Shift : An Exploration Of Union Strength In The Public Sector And Its Implications For Organized Labor In The U.S, Renee M. Branshaw

Undergraduate Theses and Senior Projects

No abstract provided.

British Pound-U.S. Dollar Swap Agreement Dated As Of December 22, 2011, Federal Reserve System: Federal Reserve Bank Of New York

Documents

No abstract provided.

Euro-U.S. Dollar Swap Agreement Dated As Of December 22, 2011, Federal Reserve System: Federal Reserve Bank Of New York

Documents

No abstract provided.

Yen-U.S. Dollar Swap Agreement Dated As Of December 21, 2011, Federal Reserve System: Federal Reserve Bank Of New York

Documents

No abstract provided.

Swiss Franc-U.S. Dollar Swap Agreement Dated As Of December 20, 2011, Federal Reserve System: Federal Reserve Bank Of New York

Documents

No abstract provided.

Canadian Dollar-U.S. Dollar Swap Agreement Dated December 20, 2011, Federal Reserve System: Federal Reserve Bank Of New York

Documents

No abstract provided.

Concepts And Models Of Empathy: Past, Present, And Future, Elizabeth Ann Baxter, Md

Jefferson Journal of Psychiatry

The subject of empathy has been increasing in popularity and importance; correspondingly, the theoretical aspects of empathy are in need of further development. This paper outlines key concepts and processes related to empathy, particularly the mechanisms of identification and regression as they are discussed in the models of empathy articulated by Fleiss, Greenson, and Jordan. Similarities and differences of the models are examined, in addition to each model's description of the roles of identification and regression. Although each model has made significant contributions towards a theoretical perspective of empathy, none of them have distinguished pathological from non-pathological uses of identification. …

The Diagnosis Of Multiple Personality Disorder, Joshua D. Mcdavid, Md, Mph

Jefferson Journal of Psychiatry

This paper represents an attempt to facilitate the clinician or psychiatrist in making a diagnosis of Multiple Personality Disorder, the most severe of the dissociative disorders. Emphasis will be placed on detecting signs, symptoms, and information that occur within the constituent parts of a typical psychiatric interview, and that are highly suggestive of MPD even in the absence of alter presentation.

Comparing Newspaper Coverage Of Climate Change During Election Campaigns In The United States, Canada And Australia, Dan Rowe

Mass Communications - Dissertations

This study compares newspaper coverage of climate change and global warming during the national elections in Australia, Canada and the U.S. during 2007 and 2008. Using a census of newspaper coverage and in-depth interviews with reporters, editors and columnists in the three countries, the study confirmed the findings of earlier studies that the political agenda shapes the news agenda when it comes to climate change coverage. However, the study did find that coverage of general climate change stories continued during the election campaign periods in the three countries. Reporters who cover either politics or environmental issues or both found it …