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Articles 901 - 930 of 938
Full-Text Articles in Entire DC Network
2020-04-25/26 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Ariel Hurwitz, Lauren Tagliaferro Epler, Alexandra Yingling, Samuel Anyona, Perez Olewe, Tudor I. Oprea, Cristian Bologa, Orrin Myers, Douglas J. Perkins
2020-04-25/26 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Ariel Hurwitz, Lauren Tagliaferro Epler, Alexandra Yingling, Samuel Anyona, Perez Olewe, Tudor I. Oprea, Cristian Bologa, Orrin Myers, Douglas J. Perkins
HSC Covid 19 Briefings
Executive Summary:
NM and Navajo Nation case reports. NM unemployment assistance. Mount Sinai experience. NYC antibody testing starts. US states reopening. US hospitals closure risk. UK universal weekly testing. Russia holiday spikes. Assessments of double-layered cloth masks. Microwave steam disinfection. N95 reuse. Ophthalmic equipment shields. Phased reopening. Inverse quarantine. Low GI endoscopy transmission. Nursing facility transmission. Predicting per-state cases. Forecasting hospital demand. Ventilator triage policies. CDC/OSHA meat processing. Antivirals and DOACs. Thrombotic ultrasound screening. Thromboembolic complications. CT findings reporting. Nasal cannulas over ventilators. Safe intubation/extubation. Convalescent plasma eligibility. Safe ultrasound. Invasive cardiac electrophysiology. Esophageal oncologic surgery. Mental health COPD. Antibody …
2020-04-23 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Rachel D. King, Jenny Situ, Lauren Tagliaferro Epler, Cleoshia Williams, Ariel Hurwitz, Ryen Ormesher, Kathryn Foos, Alexandra Yingling, Elly Munde, Evans Raballah, Cristian Bologa, Kristine Tollestrup, Douglas J. Perkins
2020-04-23 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Rachel D. King, Jenny Situ, Lauren Tagliaferro Epler, Cleoshia Williams, Ariel Hurwitz, Ryen Ormesher, Kathryn Foos, Alexandra Yingling, Elly Munde, Evans Raballah, Cristian Bologa, Kristine Tollestrup, Douglas J. Perkins
HSC Covid 19 Briefings
Executive Summary:
NM health order extension. NM and Navajo nation numbers. Pueblo relief. NM curve flattens. Economic recovery council. Businesses push to reopen. Police enforcement tough. Out-of-network healthcare billing. 3700 NM medical volunteers. Rising US deaths. Meat processor shortages. WHO malaria deaths warning. Europe: ½ of deaths nursing homes. British household testing. EU rescue package. Cybercrime 5X. NM PPE spending. PPE waste. Nylon + cloth masks. H2O2 PPE sterilization. NY 13.9% antibodies. NY risk factors. Children clinical features. Italian town infection “census”. Monitoring excess deaths. COVID-NET summary. Exit strategies. Outpatient screening. Hospital stress management. Practice guidance on: home anaphylaxis management, …
2020-04-17/18 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Lori D. Sloane, Samuel Anyona, Perez Olewe, Evans Raballh, Elly Munde, Cristian Bologa, Orrin Myers, Andrew S. Rowland, Kristine Tollestrup, Douglas J. Perkins
2020-04-17/18 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Lori D. Sloane, Samuel Anyona, Perez Olewe, Evans Raballh, Elly Munde, Cristian Bologa, Orrin Myers, Andrew S. Rowland, Kristine Tollestrup, Douglas J. Perkins
HSC Covid 19 Briefings
Executive Summary:
Daily NM Recap. Stimulus checks. Whitehouse reopening guidelines. Increased suicide calls. Commentary on COVID and African Americans. NYC ventilation rate. 300K African deaths predicted. Thai horse virus outbreak. Europe eases lockdown. UK vaccine research. Chinese death undercount. Biosafety breaches. General wearing of masks. PPE for emergency physician. FDA approves safer swabs. Mental health lockdown impact. Intermittent social distancing. Undetected US cases. NYC hospitalization characteristics. Adapting veterinary surveillance. "Infectious disease” hospital. NIH vaccine and treatment partnership. Repurposing anesthetic machines as ventilators. Guidance for psychiatrists. Elective surgery risk stratification. Hemodialysis facility. Pathologist on IgG/M tests. Abnormal coagulation and ECMO. Paramedic …
2020-04-16 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Hannah Groves, Estefania Montanez, Rachel D. Montanez, Elly Munde, Perez Olewe, Cristian Bologa, Gregory Mertz, Kristine Tollestrup, Andrew S. Rowland, Orrin Myers, Douglas J. Perkins
2020-04-16 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Hannah Groves, Estefania Montanez, Rachel D. Montanez, Elly Munde, Perez Olewe, Cristian Bologa, Gregory Mertz, Kristine Tollestrup, Andrew S. Rowland, Orrin Myers, Douglas J. Perkins
HSC Covid 19 Briefings
Executive Summary:
Daily NM recap. Public Catholic masses resume. Chaplains stand down. Food delivered to tribal communities. Governors order face coverings use. Campfires restricted. NY hospitalizations fall. Nursing home probe in NJ. GOP call WHO Chief resignation. Africa cases up 51% and deaths up 60%. Sub-Saharan Africa prediction. Resurgence in Japan. UK conditions to reopen. France deaths up. UNMH protests over PPE. Med center financial stress. Hospitals bailout insufficient. 55% US healthcare worker cases hospital spread. Cruise ship transmission. Essential contact tracing. JAMA editors discuss policy. Guideline updates: treatment, emergency dep, ophthalmology, cath lab, telemedicine, liver disease, caregiver, health care …
2020-04-14 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Hannah Groves, Danielle Rivera, Rachel D. King, Estafania Montanez, Jolene Lobo, Samuel Anyona, Evans Raballah, Cristian Bologa, Andrew S. Rowland, Kristine Tollestrup, Tudor I. Oprea, Orrin Myers, Douglas J. Perkins
2020-04-14 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Hannah Groves, Danielle Rivera, Rachel D. King, Estafania Montanez, Jolene Lobo, Samuel Anyona, Evans Raballah, Cristian Bologa, Andrew S. Rowland, Kristine Tollestrup, Tudor I. Oprea, Orrin Myers, Douglas J. Perkins
HSC Covid 19 Briefings
Executive Summary:
NMDOH county demographics online. NM emergency business loans. ABQ businesses violations. NM 5 new deaths 62 more cases. May 1 reopening too optimistic. MA contract tracing. Federal Ventilator Reserve. GM mass ventilator production. Ventilator-sharing device. $400M N-95 mask sterilization 60 sites. UNM PPE reprocessing online. Drug quality vulnerable. Managing urgent airway calls. Social distancing until 2022. SARS-Cov-2 blood supply. Contact tracing national blueprint. Mental health endangered. Successful surgical rapid response. Contact tracing medical ethics. Animal coronaviruses: human lessons. IDSA management guidelines. Ophthalmic practice. Pain management. Obstetrics management. Oncology practice. Forward triage. Scoring time-sensitive procedures. Outpatient structural heart disease. …
2020-04-10 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Samuel Anyona, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Evans Raballah, Perez Olewe, Carolyne Ndege, Hannah Groves, Danielle Rivera, Estefania Montanez, Tudor I. Oprea, Orrin Myers, Rachel D. King, Andrew S. Rowland, Kristine Tollestrup, Douglas J. Perkins
2020-04-10 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Samuel Anyona, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Evans Raballah, Perez Olewe, Carolyne Ndege, Hannah Groves, Danielle Rivera, Estefania Montanez, Tudor I. Oprea, Orrin Myers, Rachel D. King, Andrew S. Rowland, Kristine Tollestrup, Douglas J. Perkins
HSC Covid 19 Briefings
Executive Summary:
Extra NM HSD SNAP benefits. NM cases >1000. Meds supply chain threatened. Mass graves in NY. Surgeon General screening app. Presidential briefing. Italian healthcare worker deaths. Taiwan tiered care model. Communicating risks to public. French public demand hydroxychloroquine. Vaccination pause dangers. Retesting needed after discharge. CDC report geography and incidence. UW clinical informatics response. UW preparedness guidelines. Wuhan outbreak control. CDC asymptomatic exposed worker guidelines. Mask innovation. Unemployment spikes. Workforce gaps. Workspace modifications reduce transmission. Guidelines and recommendations: ER physician, surgery, cardiopulmonary resuscitation, chest imaging, geriatrics, critically ill children, postpyloric tube placement, genitourinary malignancies, obstetrics, and home work …
Copd Exacerbation Caused By Sars-Cov-2: A Case Report From The Louisville Covid-19 Surveillance Program, Forest W. Arnold, Kamran Mahmood, Angeline Prabhu, Darmaan Aden, Anupama Raghuram, Mark Burns, Leslie A. Beavin, Donghoon Chung, Kenneth E. Palmer, Julio A. Ramirez
Copd Exacerbation Caused By Sars-Cov-2: A Case Report From The Louisville Covid-19 Surveillance Program, Forest W. Arnold, Kamran Mahmood, Angeline Prabhu, Darmaan Aden, Anupama Raghuram, Mark Burns, Leslie A. Beavin, Donghoon Chung, Kenneth E. Palmer, Julio A. Ramirez
The University of Louisville Journal of Respiratory Infections
A 53-year-old male with a history of chronic obstructive pulmonary disease (COPD) on home oxygen presented to the hospital with worsening shortness of breath plus cough. He was admitted to the intensive care unit for COPD exacerbation and respiratory failure. A routine evaluation was performed, including a nasopharyngeal swab for a respiratory viral panel, which was negative. His symptoms improved over 48 hours, after which time a surveillance test for SARS-CoV-2 returned as positive. After clinical improvement, he was discharged to home isolation.
How To Prevent Covid-19 In Nurses And Physicians In The Hospital Setting: Universal Test-And-Isolate For All Patients Admitted To Hospitals, Julio A. Ramirez, Ruth Carrico, Forest W. Arnold, Paul Schulz
How To Prevent Covid-19 In Nurses And Physicians In The Hospital Setting: Universal Test-And-Isolate For All Patients Admitted To Hospitals, Julio A. Ramirez, Ruth Carrico, Forest W. Arnold, Paul Schulz
The University of Louisville Journal of Respiratory Infections
No abstract provided.
Evidence Of The Covid-19 Virus Targeting The Cns: Tissue Distribution, Host-Virus Interaction, And Proposed Neurotropic Mechanisms, Abdul Mannan Baig, Areeba Khaleeq, Usman Ali, Hira Syeda
Evidence Of The Covid-19 Virus Targeting The Cns: Tissue Distribution, Host-Virus Interaction, And Proposed Neurotropic Mechanisms, Abdul Mannan Baig, Areeba Khaleeq, Usman Ali, Hira Syeda
Department of Biological & Biomedical Sciences
The recent outbreak of coronavirus infectious disease 2019 (COVID-19) has gripped the world with apprehension and has evoked a scare of epic proportion regarding its potential to spread and infect humans worldwide. As we are in the midst of an ongoing pandemic of COVID-19, scientists are struggling to understand how it resembles and differs from the severe acute respiratory syndrome coronavirus (SARS-CoV) at the genomic and transcriptomic level. In a short time following the outbreak, it has been shown that, similar to SARS-CoV, COVID-19 virus exploits the angiotensin-converting enzyme 2 (ACE2) receptor to gain entry inside the cells. This finding …
Identifying And Mapping The Global Research Output On Coronavirus Disease: A Scientometric Study, Muneer Ahmad, Dr. M.Sadik Batcha
Identifying And Mapping The Global Research Output On Coronavirus Disease: A Scientometric Study, Muneer Ahmad, Dr. M.Sadik Batcha
Library Philosophy and Practice (e-journal)
The paper explores and analyses the trend of world literature on “Coronavirus Disease” in terms of the output of research publications as indexed in the Science Citation Index Expanded (SCI-E) of Web of Science during the period from 2011 to 2020. The study found that 6071 research records have been published on Coronavirus Disease till March 20, 2020. The various scientometric components of the research records published in the study period were studied. The study reveals the various aspects of Coronavirus Disease literature such as year wise distribution, relative growth rate, doubling time of literature, geographical wise, organization wise, language …
Response By Endodontists To The Sars-Cov-2 (Covid−19) Pandemic: An International Survey, Johnah C. Galicia, Rahma Mungia, Melanie V. Taverna, Marissa J. Mendoza, Carlos Estrela, Alexis Gaudin, Chengfei Zhang, B. A. Vaughn, Asma A. Khan
Response By Endodontists To The Sars-Cov-2 (Covid−19) Pandemic: An International Survey, Johnah C. Galicia, Rahma Mungia, Melanie V. Taverna, Marissa J. Mendoza, Carlos Estrela, Alexis Gaudin, Chengfei Zhang, B. A. Vaughn, Asma A. Khan
Pacific Faculty Work
As SARS-CoV-2 continues to wreak havoc, health care workers are on the front lines to protect our communities. Dentists, particularly endodontists who manage dental emergencies, are engaged in high risk procedures that necessitate the modification of their treatment strategies in order to protect themselves, their staff and their patients from exposure to SARS-CoV-2. This study gathered international data from 448 endodontists to describe their awareness, their clinical care modifications, their strategies for re-opening and their reflection on the effects of the pandemic on their lives. Most endodontic practitioners (78%, n = 350) provided but limited their treatments to emergency care …
Integration Of Transcriptomic Profile Of Sars-Cov-2 Infected Normal Human Bronchial Epi-Thelial Cells With Metabolic And Protein-Protein Interaction Networks, Hamza Umut Karakurt, Pinar Pi̇r
Integration Of Transcriptomic Profile Of Sars-Cov-2 Infected Normal Human Bronchial Epi-Thelial Cells With Metabolic And Protein-Protein Interaction Networks, Hamza Umut Karakurt, Pinar Pi̇r
Turkish Journal of Biology
A novel coronavirus (SARS-CoV-2, formerly known as nCoV-2019) that causes an acute respiratory disease has emerged in Wuhan, China and spread globally in early 2020. On January the 30th, the World Health Organization (WHO) declared spread of this virus as an epidemic and a public health emergency. With its highly contagious characteristic and long incubation time, confinement of SARS-CoV-2 requires drastic lock-down measures to be taken and therefore early diagnosis is crucial. We analysed transcriptome of SARS-CoV-2 infected human lung epithelial cells, compared it with mock-infected cells, used network-based reporter metabolite approach and integrated the transcriptome data with protein-protein interaction …
Sars-Cov-2 Neutralizing Antibody Development Strategies, Bertan Koray Balcioğlu, Meli̇s Deni̇zci̇ Öncü, Hasan Ümi̇t Öztürk, Fatima Yücel, Fi̇li̇z Kaya, Müge Serhatli, Hi̇vda Ülbeği̇ Polat, Şaban Teki̇n, Ayli̇n Özdemi̇r Bahadir
Sars-Cov-2 Neutralizing Antibody Development Strategies, Bertan Koray Balcioğlu, Meli̇s Deni̇zci̇ Öncü, Hasan Ümi̇t Öztürk, Fatima Yücel, Fi̇li̇z Kaya, Müge Serhatli, Hi̇vda Ülbeği̇ Polat, Şaban Teki̇n, Ayli̇n Özdemi̇r Bahadir
Turkish Journal of Biology
In December 2019 a novel coronavirus was detected in Wuhan City of Hubei Province-China. Owing to a high rate of transmission from human to human, the new virus called SARS-CoV-2 differed from others by its unexpectedly rapid spread. The World Health Organization (WHO) described the most recent coronavirus epidemic as a global pandemic in March 2020. The virus spread triggered a health crisis (the COVID-19 disease) within three months, with socioeconomic implications. No approved targeted-therapies are available for COVID-19, yet. However, it is foreseen that antibody-based treatments may provide an immediate cure for patients. Current neutralizing antibody development studies primarily …
Sars-Cov-2 Isolation And Propagation From Turkish Covid-19 Patients, Ci̇han Taştan, Bulut Yurtsever, Gözde Karakuş, Derya Di̇lek Kançaği, Sevda Demi̇r, Selen Abanuz, Utku Seyi̇s, Mülazi̇m Yildirim, Recai̇ Kuzay, Ömer Eli̇bol, Serap Arbak, Merve Açikel Elmas, Selçuk Bi̇rdoğan, Osman Uğur Sezerman, Ayşe Sesi̇n Kocagöz
Sars-Cov-2 Isolation And Propagation From Turkish Covid-19 Patients, Ci̇han Taştan, Bulut Yurtsever, Gözde Karakuş, Derya Di̇lek Kançaği, Sevda Demi̇r, Selen Abanuz, Utku Seyi̇s, Mülazi̇m Yildirim, Recai̇ Kuzay, Ömer Eli̇bol, Serap Arbak, Merve Açikel Elmas, Selçuk Bi̇rdoğan, Osman Uğur Sezerman, Ayşe Sesi̇n Kocagöz
Turkish Journal of Biology
The novel coronavirus pneumonia, which was named later as coronavirus disease 2019 (COVID-19), is caused by the severe acute respiratory syndrome coronavirus 2, namely SARS-CoV-2. It is a positive-strand RNA virus that is the seventh coronavirus known to infect humans. The COVID-19 outbreak presents enormous challenges for global health behind the pandemic outbreak. The first diagnosed patient in Turkey has been reported by the Republic of Turkey Ministry of Health on March 11, 2020. In May, over 150,000 cases in Turkey, and 5.5 million cases around the world have been declared. Due to the urgent need for a vaccine and …
Central Nervous System Complications Associated With Sars-Cov-2 Infection: Integrative Concepts Of Pathophysiology And Case Reports, S. Najjar, A. Najjar, D. J. Chong, B. K. Pramanik, C. Kirsch, R. Kuzniecky, S. Pacia, S. Azhar
Central Nervous System Complications Associated With Sars-Cov-2 Infection: Integrative Concepts Of Pathophysiology And Case Reports, S. Najjar, A. Najjar, D. J. Chong, B. K. Pramanik, C. Kirsch, R. Kuzniecky, S. Pacia, S. Azhar
Journal Articles
No abstract provided.
A Rapid, Simple, Inexpensive, And Mobile Colorimetric Assay Covid-19-Lamp For Mass On-Site Screening Of Covid-19, Franklin Wang Ngai Chow, Tony Tat Yin Chan, Anthony Raymond Tam, Suhui Zhao, Weiming Yao, Joshua Fung, Flora Ka Kei Cheng, George Chi Shing Lo, Stella Chu, Kam Leng Aw-Yong, James Yat Man Tang, Chi Ching Tsang, Hayes Kam Hei Luk, Antonio Cheuk Pui Wong, Kenneth Sze Ming Li, Longchao Zhu, Zirong He, Emily Wan Ting Tam, Tom Wai Hin Chung, Sally Cheuk Ying Wong, Tak Lun Que, Kitty Sau Chun Fung, David Christopher Lung, Alan Ka Lun Wu, Ivan Fan Ngai Hung, Patrick Chiu Yat Woo, Susanna Kar Pui Lau
A Rapid, Simple, Inexpensive, And Mobile Colorimetric Assay Covid-19-Lamp For Mass On-Site Screening Of Covid-19, Franklin Wang Ngai Chow, Tony Tat Yin Chan, Anthony Raymond Tam, Suhui Zhao, Weiming Yao, Joshua Fung, Flora Ka Kei Cheng, George Chi Shing Lo, Stella Chu, Kam Leng Aw-Yong, James Yat Man Tang, Chi Ching Tsang, Hayes Kam Hei Luk, Antonio Cheuk Pui Wong, Kenneth Sze Ming Li, Longchao Zhu, Zirong He, Emily Wan Ting Tam, Tom Wai Hin Chung, Sally Cheuk Ying Wong, Tak Lun Que, Kitty Sau Chun Fung, David Christopher Lung, Alan Ka Lun Wu, Ivan Fan Ngai Hung, Patrick Chiu Yat Woo, Susanna Kar Pui Lau
Faculty of Science & Technology (THEi)
To control the COVID-19 pandemic and prevent its resurgence in areas preparing for a return of economic activities, a method for a rapid, simple, and inexpensive point-of-care diagnosis and mass screening is urgently needed. We developed and evaluated a one-step colorimetric reverse-transcriptional loop-mediated isothermal amplification assay (COVID-19-LAMP) for detection of SARS-CoV-2, using SARS-CoV-2 isolate and respiratory samples from patients with COVID-19 (n = 223) and other respiratory virus infections (n = 143). The assay involves simple equipment and techniques and low cost, without the need for expensive qPCR machines, and the result, indicated by color change, is easily interpreted by …
Biosafety And Biosecurity Approaches To Restrain/Contain And Counter Sars-Cov-2/Covid-19 Pandemic: A Rapid-Review, Tauseef Ahmad, Haroon Haroon, Kuldeep Dhama, Khan Sharun, Fazal Mehmood Khan, Irfan Ahmed, Ruchi Tiwari, Taha Hussein Musa, Muhammad Khan, D. Katterine Bonilla-Aldana, Alfonso J. Rodriguez-Morales, Jin Hui
Biosafety And Biosecurity Approaches To Restrain/Contain And Counter Sars-Cov-2/Covid-19 Pandemic: A Rapid-Review, Tauseef Ahmad, Haroon Haroon, Kuldeep Dhama, Khan Sharun, Fazal Mehmood Khan, Irfan Ahmed, Ruchi Tiwari, Taha Hussein Musa, Muhammad Khan, D. Katterine Bonilla-Aldana, Alfonso J. Rodriguez-Morales, Jin Hui
Turkish Journal of Biology
Emergence and reemergence of infectious diseases pose significant public health risks that are continuously haunting human civilization in the past several decades. Such emerging pathogens should be considered as a high threat to humans, animals, and environmental health. The year 2020 was welcomed by another significant virus from family Coronaviridae called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that caused the coronavirus disease 2019 (COVID-19). The disease was first reported in the city of Wuhan, Hubei province, China. Within a short time, this disease attained the status of the Public Health Emergency of International Concern. Presently, COVID-19 has spread to …
Using Probiotics To Flatten The Curve Of Coronavirus Disease Covid-2019 Pandemic., David Baud, Varvara Dimopoulou Agri, Glenn R Gibson, Gregor Reid, Eric Giannoni
Using Probiotics To Flatten The Curve Of Coronavirus Disease Covid-2019 Pandemic., David Baud, Varvara Dimopoulou Agri, Glenn R Gibson, Gregor Reid, Eric Giannoni
Microbiology & Immunology Publications
No abstract provided.
Safety And Efficacy Of Tocilizumab In The Treatment Of Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia: A Retrospective Cohort Study, Atul Patel, Kinjal Shah, Mitkumar Dharsandiya, Ketan Patel, Tushar Patel, Mukesh Patel, Tea Reljic, Ambuj Kumar
Safety And Efficacy Of Tocilizumab In The Treatment Of Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia: A Retrospective Cohort Study, Atul Patel, Kinjal Shah, Mitkumar Dharsandiya, Ketan Patel, Tushar Patel, Mukesh Patel, Tea Reljic, Ambuj Kumar
All publications
Background: Cytokine release storm (CRS) in severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) is thought to be the cause for organ damage and death which is independent of the actual viral burden. Tocilizumab (TCZ), an interleukin-6 receptor antagonist, is approved for the treatment of CRS. We describe the efficacy and safety of TCZ in SARS CoV-2 pneumonia. Methods: This retrospective study was conducted at a tertiary care hospital from April 20 2020 to May 21 2020. The primary endpoint was the cumulative incidence of a composite of either need for admission to the intensive care unit (ICU) with invasive mechanical …
Development And Validation Of A Model For Individualized Prediction Of Hospitalization Risk In 4,536 Patients With Covid-19, Lara Jehi, Xinge Ji, Alex Milinovich, Serpil Erzurum, Amy Merlino, Steve Gordon, James B. Young, Michael W. Kattan
Development And Validation Of A Model For Individualized Prediction Of Hospitalization Risk In 4,536 Patients With Covid-19, Lara Jehi, Xinge Ji, Alex Milinovich, Serpil Erzurum, Amy Merlino, Steve Gordon, James B. Young, Michael W. Kattan
All publications
Background: Coronavirus Disease 2019 is a pandemic that is straining healthcare resources, mainly hospital beds. Multiple risk factors of disease progression requiring hospitalization have been identified, but medical decision-making remains complex.
Objective: To characterize a large cohort of patients hospitalized with COVID-19, their outcomes, develop and validate a statistical model that allows individualized prediction of future hospitalization risk for a patient newly diagnosed with COVID-19.
Design: Retrospective cohort study of patients with COVID-19 applying a least absolute shrinkage and selection operator (LASSO) logistic regression algorithm to retain the most predictive features for hospitalization risk, followed by validation in a temporally …
Modeling The Role Of Asymptomatics In Infection Spread With Application To Sars-Cov-2, Hana M. Dobrovolny
Modeling The Role Of Asymptomatics In Infection Spread With Application To Sars-Cov-2, Hana M. Dobrovolny
All publications
SARS-CoV-2 started causing infections in humans in late 2019 and has spread rapidly around the world. While the number of symptomatically infected and severely ill people is high and has overwhelmed the medical systems of many countries, there is mounting evidence that some of the rapid spread of this virus has been driven by asymptomatic infections. In this study, we use a compartmental mathematical model of a viral epidemic that includes asymptomatic infection to examine the role of asymptomatic individuals in the spread of the infection. We apply the model to epidemics in California, Florida, New York, and Texas, finding …
The Impact Of Covid-19 On Hiv Treatment And Research: A Call To Action., Tiffany Chenneville, Kemesha Gabbidon, Patricia Hanson, Cashea Holyfield
The Impact Of Covid-19 On Hiv Treatment And Research: A Call To Action., Tiffany Chenneville, Kemesha Gabbidon, Patricia Hanson, Cashea Holyfield
All publications
The impact of the COVID-19 pandemic is far reaching, with devastating effects on individuals, communities, and societies across the world. People with chronic health conditions may be at greater risk of contracting or experiencing complications from COVID-19. In addition to illness or death for those who contract the virus, the physical distancing required to flatten the curve of new cases is having a negative impact on the economy, the effects of which intersect with mental health and other existing health concerns, thus affecting marginalized communities. Given that HIV also has a disproportionate impact on marginalized communities, COVID-19 is affecting people …
Aerosol And Surface Contamination Of Sars-Cov-2 Observed In Quarantine And Isolation Care, Joshua L. Santarpia, Danielle N. Rivera, Vicki L. Herrera, M. Jane Morwitzer, Hannah M. Creager, George W. Santarpia, Kevin K. Crown, David Brett-Major, Elizabeth R. Schnaubelt, M. Jana Broadhurst, James V. Lawler, St. Patrick Reid, John Lowe
Aerosol And Surface Contamination Of Sars-Cov-2 Observed In Quarantine And Isolation Care, Joshua L. Santarpia, Danielle N. Rivera, Vicki L. Herrera, M. Jane Morwitzer, Hannah M. Creager, George W. Santarpia, Kevin K. Crown, David Brett-Major, Elizabeth R. Schnaubelt, M. Jana Broadhurst, James V. Lawler, St. Patrick Reid, John Lowe
Journal Articles: Epidemiology
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated in Wuhan, China in late 2019, and its resulting coronavirus disease, COVID-19, was declared a pandemic by the World Health Organization on March 11, 2020. The rapid global spread of COVID-19 represents perhaps the most significant public health emergency in a century. As the pandemic progressed, a continued paucity of evidence on routes of SARS-CoV-2 transmission has resulted in shifting infection prevention and control guidelines between classically-defined airborne and droplet precautions. During the initial isolation of 13 individuals with COVID-19 at the University of Nebraska Medical Center, we collected air …
Acute Encephalopathy With Elevated Csf Inflammatory Markers As The Initial Presentation Of Covid-19, Shelli Farhadian, Laura R. Glick, Chantal B. F. Vogels, Jared Thomas, Jennifer Chiarella, Arnau Casanovas-Massana, Jing Zhou, Camila Odio, Pavithra Vijayakumar, Bertie Geng, John Fournier, Santos Bermejo, Joseph R. Fauver, Tara Alpert, Anne L. Wyllie, Cynthia Turcotte, Matthew Steinle, Patrick Paczkowski, Charles Dela Cruz, Craig Wilen, Albert I. Ko, Sean Mackay, Nathan D. Grubaugh, Serena Spudich, Lydia Aoun Barakat
Acute Encephalopathy With Elevated Csf Inflammatory Markers As The Initial Presentation Of Covid-19, Shelli Farhadian, Laura R. Glick, Chantal B. F. Vogels, Jared Thomas, Jennifer Chiarella, Arnau Casanovas-Massana, Jing Zhou, Camila Odio, Pavithra Vijayakumar, Bertie Geng, John Fournier, Santos Bermejo, Joseph R. Fauver, Tara Alpert, Anne L. Wyllie, Cynthia Turcotte, Matthew Steinle, Patrick Paczkowski, Charles Dela Cruz, Craig Wilen, Albert I. Ko, Sean Mackay, Nathan D. Grubaugh, Serena Spudich, Lydia Aoun Barakat
Journal Articles: Epidemiology
BACKGROUND: COVID-19 is caused by the severe acute respiratory syndrome virus SARS-CoV-2. It is widely recognized as a respiratory pathogen, but neurologic complications can be the presenting manifestation in a subset of infected patients.
CASE PRESENTATION: We describe a 78-year old immunocompromised woman who presented with altered mental status after witnessed seizure-like activity at home. She was found to have SARS-CoV-2 infection and associated neuroinflammation. In this case, we undertake the first detailed analysis of cerebrospinal fluid (CSF) cytokines during COVID-19 infection and find a unique pattern of inflammation in CSF, but no evidence of viral neuroinvasion.
CONCLUSION: Our findings …
An Evaluation Of Florida’S Zika Response Using The Who Health Systems Framework: Can We Apply These Lessons To Covid-19?, Jennifer Marshall, Blake Scott, Jennifer Delva, Cedrick Ade, Santiago Hernandez, Jaladhikumar Patel, Mantero Moreno-Cheek, Dogeli Rojas, Jean-Paul Tanner, Russell S. Kirby
An Evaluation Of Florida’S Zika Response Using The Who Health Systems Framework: Can We Apply These Lessons To Covid-19?, Jennifer Marshall, Blake Scott, Jennifer Delva, Cedrick Ade, Santiago Hernandez, Jaladhikumar Patel, Mantero Moreno-Cheek, Dogeli Rojas, Jean-Paul Tanner, Russell S. Kirby
All publications
Objectives: From 2016 to 2018 Florida documented 1471 cases of Zika virus, 299 of which were pregnant women (Florida Department of Health, https://www.floridahealth.gov/diseases-and-conditions/mosquito-bornediseases/surveillance.html , 2019a). Florida's response required unprecedented rapid and continuous cross-sector communication, adaptation, and coordination. Zika tested public health systems in new ways, particularly for maternal child health populations. The systems are now being challenged again, as the Coronavirus COVID-19 pandemic spreads throughout Florida. This qualitative journey mapping evaluation of Florida's response focused on care for pregnant women and families with infants exposed to Zika virus.
Methods: Fifteen focus groups and interviews were conducted with 33 public health …
Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky
Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky
Molecular Medicine Faculty Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans …
Crushing The Curve, The Role Of National And International Institutions And Policy Makersin Covid-19 Pandemic, Zeli̇ha Koçak Tufan, Bi̇rcan Kayaaslan
Crushing The Curve, The Role Of National And International Institutions And Policy Makersin Covid-19 Pandemic, Zeli̇ha Koçak Tufan, Bi̇rcan Kayaaslan
Turkish Journal of Medical Sciences
Nobody can be fully prepared to a pandemic. Of course there are signs of it, the scientists can predict, alarming speeches can be made. But there are always alarmist people around, maybe that is why sometimes even the most serious warnings may be not considered by the authorities on time. The first patients may be lost without a proper diagnosis. When everybody realizes that there may be a big problem in the horizon, sometimes it is too late. That is why it is very important to monitor contagious diseases and follow the warnings and releases of national and international disease …
The Covid-19 Response In Nebraska: How Students Answered The Call, Sabrine Chengane, Anlan Cheney, Sierra Garth, Sharon J. Medcalf
The Covid-19 Response In Nebraska: How Students Answered The Call, Sabrine Chengane, Anlan Cheney, Sierra Garth, Sharon J. Medcalf
Journal Articles: Epidemiology
The Student Response Team at the University of Nebraska Medical Center answered the statewide call to assist local health departments during the coronavirus disease 2019 (COVID-19) pandemic. As a voluntary student-led effort, the SRT assisted health departments to conduct contact tracing, monitor social media, and educate the public. Their experience demonstrates how students can increase the public health surge capacity of local health departments while gaining applied experience during public health emergencies. This call-to-action commentary proposes that SRTs should be formed, trained, and deployed through academic institutions across the nation and the globe, during and beyond the current pandemic.
Comparative Evaluation Of The Origin, Evolution, Transmission, Diagnosis, And Vaccine Development Of Three Highly Pathogenic Human Coronaviruses (Sars-Cov, Mers-Cov And Sars-Cov-2), Prabhu Dutta Shaw, Nicky Patel, Shailee Patil, Richard Samuel
Comparative Evaluation Of The Origin, Evolution, Transmission, Diagnosis, And Vaccine Development Of Three Highly Pathogenic Human Coronaviruses (Sars-Cov, Mers-Cov And Sars-Cov-2), Prabhu Dutta Shaw, Nicky Patel, Shailee Patil, Richard Samuel
Open Access archive
Coronavirus infection in humans is not uncommon. The first coronavirus (HCoV-229E) in humans was isolated in 1965. Subsequently, three more coronaviruses were recognized: HCoV-NL63, HCoV-HKU1, and HCoV-229E. These viruses are endemic in humans and cause common cold and mild respiratory infections throughout the year. The three coronaviruses, SARS-CoV, MERS-CoV, and SARS-CoV-2 are highly pathogenic coronaviruses that cause very severe respiratory diseases in human. SARS-CoV-2 is a newly emerging coronavirus posing pandemic COVID-19 disease that has disrupted the human life in many ways. In this review, the origin, evolution, transmission, vaccine development, and clinical characteristics of these highly pathogenic human coronaviruses …
Recovering From Covid-19 Building Closures: Guidance Document, David Krause, Cheri Marcham, John Springston, Alex Lebeau, Robert Rottersman, Timothy Froehlig, Bart Ashley
Recovering From Covid-19 Building Closures: Guidance Document, David Krause, Cheri Marcham, John Springston, Alex Lebeau, Robert Rottersman, Timothy Froehlig, Bart Ashley
Publications
While the country comes to terms with the inevitable impact that SARS-CoV-2, the virus that causes COVID-19, will have on our lives and communities, public health authorities remain focused on breaking the chain of transmission. Managing the risk has resulted in widespread closures of businesses, schools, universities, resorts, and other facilities deemed “non-essential.” Practically speaking, this means closing buildings and ceasing operations. For building owners and operators, this poses a significant challenge to protect their assets and to ensure they are ready to reoccupy once the pandemic subsides.