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Physiology

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The Development Of General Anesthesia, Andrew Williams Jan 2014

The Development Of General Anesthesia, Andrew Williams

Theses & ETDs

This thesis was structured into two distinct parts. The first part is a brief history of the development of both the field of anesthesia and anesthetic agents, while the second part is focused on the last 100 years and is less about the history of anesthesia and more about the pharmacological properties of the anesthetics and their effects on human physiology. Regarding the history section, I chose to highlight those people and events that I felt most important to the development of the field of anesthesia. The latter section is meant to delve more into the chemistry and biology associated …

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A Theoretical Adaptive Autonomy Model: Real-Time Physiological Assessment Of Cognitive Workload, Dakota C. Evans Jan 2014

A Theoretical Adaptive Autonomy Model: Real-Time Physiological Assessment Of Cognitive Workload, Dakota C. Evans

Browse all Theses and Dissertations

Increases in modern-day system complexity, has led for a need to improve human performance and the interaction between the two. Three objectives: (1) to investigate physiological measures as indicators of cognitive workload, (2) to assess cognitive workload during human interaction with different autonomy levels, and (3) to develop a theoretical model for an adaptive autonomous system that changes with real-time cognitive workload measures were addressed. This effort seeks to improve human computer interaction by providing the human with the acceptable level of computer automation based on real-time cognitive state. Two experiments involved collection of measures of subject physiology, subjective survey …

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Involvement Of Cytochromep4504a In Adenosine A1 Receptor Mediated Regulation Of Vascular Tone, Swati S Kunduri Aug 2013

Involvement Of Cytochromep4504a In Adenosine A1 Receptor Mediated Regulation Of Vascular Tone, Swati S Kunduri

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cardiovascular diseases are one of the leading causes of morbidity and mortality worldwide. The regulation of vascular tone plays an important role in normal cardiovascular function. Adenosine, an autacoid has several physiological and pathophysiological roles, apart from the regulation of vascular tone. Adenosine receptor (AR) contracts and relaxes blood vessels through all four subtypes (A1, A2A, A2B, and A3) linked to different signaling mechanisms. Deciphering complex tissue responses remains difficult because relationships of individual receptor subtypes and various end-effectors (e.g., ion channels) are yet to be identified. Apart from adenosine, 20-HETE, a cytochrome P4504a (Cyp4a) metabolite of arachidonic acid (AA) …

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Physiology Of Yawning : Proximate Mechanisms Supporting An Ultimate Function, Melanie Lee Shoup-Knox Jan 2011

Physiology Of Yawning : Proximate Mechanisms Supporting An Ultimate Function, Melanie Lee Shoup-Knox

Legacy Theses & Dissertations (2009 - 2024)

Recent research suggests that yawning functions to cool the brain during periods of mild hyperthermia. Evidence for this hypothesis is largely behavioral, and includes reports of increased yawning during increases in ambient temperature and times of stress as well as an amelioration of yawning upon nasal breathing and forehead cooling. Little research has been published on the physiological mechanisms supporting a brain cooling function, however. The current set of studies explores human and animal physiological parameters in search of evidence of brain cooling during yawning. In humans, heart rate, skin temperature, and skin conductance findings suggest that yawning involves an …

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Effects Of Blood Glucose Elevation On The Structure And Function Of Microvascular Networks Of Skeletal Muscle In Mice, Melissa Katherine-Barrell Georgi May 2010

Effects Of Blood Glucose Elevation On The Structure And Function Of Microvascular Networks Of Skeletal Muscle In Mice, Melissa Katherine-Barrell Georgi

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Diabetes Mellitus and its precursor, pre-diabetes, are metabolic disorders that are characterized by high levels of elevated blood glucose. This work addresses the effects of these diseases on the microvasculature of the peripheral cardiovascular system including endothelial dysfunction and capillary rarefaction, which lead to circulation problems and secondary complications. The purpose of this study is to develop an understanding of the arteriolar network architecture and function in peripheral skeletal muscle in the normal mouse and to investigate the effects of alterations in blood glucose. We demonstrate that only two hours of elevated glucose concentration decreases dilatory responses in both endothelium …

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The Effectiveness Of Active And Traditional Teaching Techniques In The Orthopedic Assessment Laboratory, Sara Nottingham Jan 2010

The Effectiveness Of Active And Traditional Teaching Techniques In The Orthopedic Assessment Laboratory, Sara Nottingham

Athletic Training Faculty Articles and Research

Active learning is a teaching methodology with a focus on student-centered learning that engages students in the educational process. This study implemented active learning techniques in an orthopedic assessment laboratory, and the effects of these teaching techniques. Mean scores from written exams, practical exams, and final course evaluations were compared for 79 human physiology students. One- and two-way analyses of variance were used to evaluate the effect of teaching methodology on test scores and evaluation responses. No significant differences were found for course evaluation responses and written and practical exam scores between the two learning groups. This study suggests that …

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Fero Corpum Ferri An Exploration Of The Role Of Human Physiology Against A Backdrop Of Everincreasing Mechanical Supplantation, David Bennett Jan 2010

Fero Corpum Ferri An Exploration Of The Role Of Human Physiology Against A Backdrop Of Everincreasing Mechanical Supplantation, David Bennett

Theses & ETDs

This essay, Fero Corpum Ferri, is meant to accompany a thesis exhibition, comprised of paintings and drawings. The paintings are executed on a medium scale, composed of brightly colored anatomical, mechanical, and invented shapes. They intimate a Pop art or graffiti sensibility that remains coolly detached while approaching varying levels of anatomical and schematic depictions � from organs and machinery to cellular abstraction and invented mechanisms. The project continues the investigation of the tensions between humanity and the growing industrial landscape begun by the Dadaists in the early 20th century. The paintings and drawings in this series invoke metaphors for …

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Minimum Criteria For Dna Damage-Induced Phase Advances In Circadian Rhythms, Christian I. Hong, Judit Zámborszky, Attila Csikász-Nagy May 2009

Minimum Criteria For Dna Damage-Induced Phase Advances In Circadian Rhythms, Christian I. Hong, Judit Zámborszky, Attila Csikász-Nagy

Dartmouth Scholarship

Robust oscillatory behaviors are common features of circadian and cell cycle rhythms. These cyclic processes, however, behave distinctively in terms of their periods and phases in response to external influences such as light, temperature, nutrients, etc. Nevertheless, several links have been found between these two oscillators. Cell division cycles gated by the circadian clock have been observed since the late 1950s. On the other hand, ionizing radiation (IR) treatments cause cells to undergo a DNA damage response, which leads to phase shifts (mostly advances) in circadian rhythms. Circadian gating of the cell cycle can be attributed to the cell cycle …

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Energy-Flow – A New Perspective On James Macgregor Burns’ Transforming Leadership: A New Pursuit Of Happiness, Pi-Jern Caroline Fu Jan 2008

Energy-Flow – A New Perspective On James Macgregor Burns’ Transforming Leadership: A New Pursuit Of Happiness, Pi-Jern Caroline Fu

Antioch University Dissertations & Theses

This theoretical dissertation documents a personal transforming leadership experience; during which, I explored my Leadership as Energy-Flow model by having a virtual dialogue with the polymathic works of theorists and thinkers to corroborate and refine it. The model consists of a theory and a conceptual scheme. The energy-flow theory, based on the laws of physics and Chinese philosophy and cosmological science, fashions the energy-flow conceptual scheme. Using the conceptual scheme, I delve into the Premise of the Dialogue, “In what ways and to what extent would using the energy-flow frame of reference describe and stimulate new meanings in Transforming Leadership: …

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