Digital Commons Network^™

Development Of Diabetes And Obesity In Infants Of Diabetic Mothers, Breanna Ritchie

Nursing Capstones

No abstract provided.

Obesity, Type 2 Diabetes, And Dietary Acculturation Among Foreign-Born Blacks In New York City, Margrethe F. Horlyck-Romanovsky

Dissertations and Theses

Background: Black immigration to the US quadrupled between 1980 and 2000, and between 2000 and 2013 it further increased by 56%. The US Census estimates that by 2060, 16.5% of the US Black population will be foreign-born. Half of all foreign-born Blacks (FBBs) in the US, or more than 1.9 million people, are from the Caribbean, and of those, 682,000 were born in Jamaica alone. Besides the Caribbean, there are 1.36 million immigrants from sub-Saharan Africa. In New York City, non-Hispanic black Caribbean and West African immigrants constitute 19% and 4%, respectively, of the total foreign-born population. Research is limited …

Adropin: An Endocrine Link Between The Biological Clock And Cholesterol Homeostasis, Sarbani Ghoshal, Joseph R. Stevens, Cyrielle Billon, Clemence Girardet, Sadichha Sitaula, Arthur S. Leon, D.C. Rao, James S. Skinner, Tuomo Rankinen, Claude Bouchard, Marinelle V. Nuñez, Kimber L. Stanhope, Deborah A. Howatt, Alan Daugherty, Jinsong Zhang, Matthew Schuelke, Edward P. Weiss, Alisha R. Coffey, Brian J. Bennett, Praveen Sethupathy, Thomas P. Burris, Peter J. Havel, Andrew A. Butler

Physiology Faculty Publications

Objective

Identify determinants of plasma adropin concentrations, a secreted peptide translated from the Energy Homeostasis Associated (ENHO) gene linked to metabolic control and vascular function.

Methods

Associations between plasma adropin concentrations, demographics (sex, age, BMI) and circulating biomarkers of lipid and glucose metabolism were assessed in plasma obtained after an overnight fast in humans. The regulation of adropin expression was then assessed in silico, in cultured human cells, and in animal models.

Results

In humans, plasma adropin concentrations are inversely related to atherogenic LDL-cholesterol (LDL-C) levels in men (n = 349), but not in women (n = …

Independent Association Of Resting Energy Expenditure With Blood Pressure: Confirmation In Populations Of The African Diaspora, Chloe Creber, Richard S. Cooper, Jacob Plange-Rhule, Pascal Bovet, Estelle V. Lambert, Terrence E. Forrester, Dale Schoeller, Walter Riesen, Wolfgang Korte, Guichan Cao, Amy Luke, Lara R. Dugas

Faculty Publications

Background: Obesity is a major risk factor for hypertension, however, the physiologic mechanisms linking increased adiposity to elevations in blood pressure are not well described. An increase in resting energy expenditure (REE) is an obligatory consequence of obesity. Previous survey research has demonstrated that REE is an independent predictor of blood pressure, and eliminates the co-linear association of body mass index. This observation has received little attention and there have been no attempts to provide a causal explanation. Methods: At baseline in an international comparative study on obesity, 289 participants aged 25-44 were recruited from communities in the US, the …

Eight Weeks Of Resistance Training In Conjunction With Glutathione And L-Citrulline Supplementation Increases Lean Mass And Has No Adverse Effects On Blood Clinical Safety Markers In Resistance-Trained Males, Paul Hwang, Flor E. Morales Marroquín, Josh Gann, Tom Andre, Sarah K. Mckinley-Barnard, Caelin Kim, Masahiko Morita, Darryn S. Willoughby

Faculty and Student Publications (Open Access)

No abstract provided.

Effectiveness Of A Community-Based Health Promotion “Rethink Your Drink” On Reducing Sugary Beverage Consumption: A Case Study, Priscilla Maghrabi, Miranda S. Terry

Faculty & Staff Research and Creative Activity

Introduction: Obesity rates are rising throughout the United States. As a way to address obesity in a rural city in southwest Kentucky, researchers conducted a “Rethink Your Drink” challenge. The purpose of this study was to evaluate the effectiveness of a community health program in reducing the consumption of sugary beverages.

Methods: Researchers conducted a “Rethink Your Drink” Challenge in a rural city in southwest Kentucky. Educational materials illustrated how beverages fell into red, yellow, or green light categories based on sugar content. Materials were provided to corporate sponsors throughout a rural city in southwest Kentucky. Community members (n=296) volunteered …

Child Care Teachers’ Knowledge Of Fun Physical Activities And Healthy Food Choices For Pre-School Children, Elizabeth Gwyn

Nursing Theses and Capstone Projects

The focus of this project was to explore child-care teachers’ knowledge of fun physical activities and healthy food choice activities for preschool children. A four-week educational session was implemented in a rural child-care center. The intervention provided education in relationship to the implementation of fun physical activities and healthy food choice activities for child-care teachers during preschoolers structured playtime. The Child Care Teachers’ Knowledge Evaluation (CCTKE) tool developed by the doctoral student was used to collect responses from participants before and after the intervention. The participants’ data was analyzed using a t-test. There were no statistically significant differences between the …

Obesity And Eating Disorders Prevention Programs: Effects On Adolescents And Young Adults With Weight Related Conditions, Jean Marie Parsons

All Electronic Theses and Dissertations

Background: With implementation of healthy weight education programs throughout schools, questions have been raised whether a preoccupation with obesity prevention contributes to an increase in the incidence of eating disorders. The purpose of this critical review of research is to compare obesity prevention programs and eating disorder prevention programs and possible unintended negative effects on adolescents with weight-related conditions. Theoretical Framework: Neuman Systems Model and Erickson’s Psychosocial Development were used. While Neuman theorizes a human being is a total person characterized by physiological, psychological, sociocultural, spiritual, and developmental factors, Erickson focuses on identity versus role confusion at the adolescent age. …

Metabolic Obesity Phenotypes And Risk Of Colorectal Cancer In Postmenopausal Women., G. C. Kabat, M. Y. Kim, M. Stefanick, G. Y. F. Ho, D. S. Lane, A. O. Odegaard, M. S. Simon, J. W. Bea, J. Luo, T. E. Wassertheil-Smoller

Journal Articles

Obesity has been postulated to increase the risk of colorectal cancer by mechanisms involving insulin resistance and the metabolic syndrome. We examined the associations of body mass index (BMI), waist circumference, the metabolic syndrome, metabolic obesity phenotypes and homeostasis model-insulin resistance (HOMA-IR-a marker of insulin resistance) with risk of colorectal cancer in over 21,000 women in the Women's Health Initiative CVD Biomarkers subcohort. Women were cross-classified by BMI (18.5-

Role Of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-Sdkp) And Renal Hemodynamics On Obesity Related Renal Damage, Mani Maheshwari

Theses, Dissertations and Capstones

Obesity is a public health problem and is associated with salt-sensitive hypertension, kidney inflammation and fibrosis. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a tetra-peptide with anti-inflammatory and anti-fibrotic properties but its effect on kidney damage in obesity is unknown. We hypothesized that high salt fed Zucker obese (ZO) rats develop renal damage, inflammation and fibrosis and that Ac-SDKP prevents these changes. Zucker lean (ZL) rats served as controls. Animals were treated with Ac-SDKP while maintained on either a normal-salt or HS diet for 8 weeks. Systolic blood pressure (SBP), albuminuria, renal inflammation and fibrosis were evaluated. HS diet increased macrophage infiltration in the …

Canada: Obesity, Marissa Olson

Global Public Health

Canada is a country with a relatively healthy population of approximately 37 million people. Canada has few major public health problems; however, Canada has experienced a rise of obesity in its population with a higher rise in the adult population than childhood. The male population is at a greater risk of becoming obese than the female population, and people 35 years old and over than below 35 years old. This brief discusses the effects of obesity, Canada’s interventions to obesity such as surgery, drugs, and healthier school lunches, and a possible new method of health counseling or more convenient healthier …

Palau: Obesity, Tavia Weis

Global Public Health

Located in the heart of the Western Pacific Ocean is a large group of small islands that make up the country of Palau. Known for its growing tourism, beautiful landscapes, and cultural beliefs. Although the country is developing, the current health issue of obesity is a growing concern. With almost half of the population obese and the other half in jeopardy, the rising concerns of the obesity epidemic have taken global news and brought the attention of major countries to try and fix these rising issues. This public health brief will discuss the problems of obesity in Palau and the …

Obesity, Noah Rhodes

Global Issues in Public Health

Obesity is a worldwide issue that can be defined as a non-communicable condition which means that it is non-infectious and non-transmissible and it is defined as having a BMI over 30 even though BMI doesn’t account for the person’s muscle mass which causes some athletes to be considered obese just because they weigh a lot for their height. Diagnosing obesity can be a long process which includes a health history being taken, a general physical exam, calculation of BMI, and measuring waist circumference. Diagnosis of obesity also involves checking for problems such as high blood pressure, variation of cholesterol levels …

Neck Circumference Positively Relates To Cardiovascular Risk Factors In College Students, Oluremi A. Famodu, Makenzie L. Barr, Sarah E. Colby, Wenjun Zhou, Ida Holaskova, Miriam P. Leary, Carol Bryd-Bredbenner, Anne E. Matthews, Melissa D. Olfert

Faculty & Staff Scholarship

The objective of this study was to determine the relationship between neck circumference (NC) and other anthropometric measures and examine cut-off points for males and females according to existing waist circumference cut-off levels in this age group. Across 8 universities, 1562 students underwent a physical assessment. Spearman rho correlations (ρ) were calculated to determine associations between NC and other continuous variables of health. Receiving operating characteristic curves were constructed to assess the optimal cut-off levels of NC of males and females with central obesity. Participants were predominantly Caucasian (67%), female (70%), and outside of Appalachia 2 (82%). Forty-one percent of …

The Effect Of Icook 4-H, A Childhood Obesity Prevention Program, On Blood Pressure And Quality Of Life In Youth And Adults: A Randomized Control Trial, Melissa D. Olfert, Oluremi A. Famodu, Sue M. Flanagan, E Smith, M. P. Leary, Rebecca L. Hagedorn, J. A. White, M. M. Koenings, Sarah E. Colby, Kendra Kattelmann, Lisa Franzen-Castle, Adrienne White

Faculty & Staff Scholarship

Objective: Obesity increases the risk of developing hypertension and from population-based samples with estimations that of 2-4% of the U.S. pediatric population has hypertension, which may affect quality of life. This study examined the effects of an obesity prevention program on blood pressure and quality of life in youth and adult participants.
Methods: A multi-state research team recruited treatment dyads (youth and their adult meal preparer) to participate in a 12-week randomized control trial and follow-up through 24 months. The treatment group received a cooking and physical activity intervention, followed by booster sessions and mailed newsletters over the remaining two-year …

Effects Of Tunable, 3d-Bioprinted Hydrogels On Human Brown Adipocyte Behavior And Metabolic Function, Mitchell Kuss, Jiyoung Kim, Dianjun Qi, Shaohua Wu, Yuguo Lei, Soonkyu Chung, Bin Duan

Department of Nutrition and Health Sciences: Faculty Publications

Obesity and its related health complications cause billions of dollars in healthcare costs annually in the United States, and there are yet to be safe and long-lasting anti-obesity approaches. Using brown adipose tissue (BAT) is a promising approach, as it uses fats for energy expenditure. However, the effect of the microenvironment on human thermogenic brown adipogenesis and how to generate clinically relevant sized and functioning BAT are still unknown. In our current study, we evaluated the effects of endothelial growth medium exposure on brown adipogenesis of human brown adipose progenitors (BAP). We found that pre-exposing BAP to angiogenic factors promoted …

The Relationship Between Body Mass Index, Binge Eating Disorder And Suicidality, Kristal Lyn Brown, Jessica Gokee Larose, Briana Mezuk

Health Policy Publications

Background
While restrictive and compensatory eating disorders (e.g. anorexia and bulimia) are associated with elevated risk of suicide, less is known about binge eating disorder (BED). There is suggestive evidence of a U-shaped relationship between body mass index (BMI) and completed suicide, but fewer studies on suicidal ideation or attempts. This study examined the association between BED, BMI, and suicidality, and assessed whether these relationships varied by gender.

Methods
Data come from the Collaborative Psychiatric Epidemiologic Surveys (N = 14,497). Binge episodes and BED were assessed using the Composite International Diagnostic Inventory (CIDI). BMI was calculated from self-reported height …

Cardiorespiratory Fitness And The Relationship Between Body Fat And Resting Testosterone In Men, Peter Hosick, Evan Matthews, Steven Leigh

Department of Exercise Science and Physical Education Scholarship and Creative Works

Objective: To examine the effect of cardiovascular fitness, i.e. VO2max, on the relationship between weight status and resting testosterone level (RTL) in males. Materials and methods: A subset of male participants from the 2003–2004 National Health and Nutrition Examination Survey were analyzed by weight status, i.e. normal, overweight, obese, and all participants. Bivariate correlation coefficients were computed for RTL, percent body fat (BF%), and VO2max. Partial correlation coefficients were computed between RTL and BF% controlling for VO2max and between RTL and VO2max controlling for BF%. Results: Bivariate correlations between RTL and BF%, and RTL and VO2max were significant in all …

The Effects Of Wearable Fitness Devices On Pediatric Obesity: An Integrative Literature Review, Kevin Sabina

Honors Undergraduate Theses

Childhood obesity is a foremost concern throughout the health care community. Approximately 17.6% of the pediatric population meet the criteria for obesity, which can lead to health disparities later in life, such as hypertension, type 2 diabetes mellitus, and metabolic syndrome. Emerging mobile and wearable lifestyle tracking devices can be a viable solution to the challenging problem of childhood obesity through behavior changes, feasibility, and adherence. The purpose of this literature review was to determine the effect that mobile and wearable activity tracking devices have on the obese pediatric population. A centralized review of the literature was conducted using various …

Weight Management Related Factors And Healthy Behaviors In Adults, Sumadhuri Pamarthi

Electronic Theses and Dissertations

Obesity is an ongoing global pandemic that affects more than one in three adults in the United States. Being overweight or obese also increases the risk of chronic health conditions. Weight management does not only center on immediate weight loss but also on the proper maintenance of an appropriate body weight over the years. Methods of weight management include eating a healthy diet and meeting physical activity guidelines. Such weight management practices are important to ensure that the people suffering from obesity can decrease risks of morbidity or even mortality. Nevertheless, unhealthy weight management strategies might lead to unintended health …

Using Social Cognitive Theory To Predict Counseling Behaviors In Registered Dietitians, Marianela Guerrero

Walden Dissertations and Doctoral Studies

Obesity and morbid obesity affect more than 30% of Americans, which emulates the rate of smoking as the leading preventable cause of disease and death in the United States. The prevalence of obesity among adults in the United States increased dramatically between 1980 and 2010 (16% to 36%). The integration of the social cognitive theory (SCT) constructs such as self-efficacy, self-control, environment and expectations in the study instrument allowed identifying the impact of personal, social and economic factors on Registered Dietitians (RDs) counseling behaviors with obese clients. The goal of this quantitative cross sectional study was to investigate the association …

Novel Anti-Obesity Effects Of Beer Hops Compound Xanthohumol: Role Of Ampk Signaling Pathway, Janaiya S Samuels, Rangaiah Shashidharamurthy, Srujana Rayalam

PCOM Scholarly Works

Background: Obesity alters adipose tissue metabolic and endocrine functioning, leading to an increased adiposity and release of pro-inflammatory cytokines. Various phytochemicals have been reported to contribute to the beiging of white adipose tissue in order to ameliorate obesity by increasing thermogenesis. Here, we show that the prenylated chalcone, xanthohumol (XN), induces beiging of white adipocytes, stimulates lipolysis, and inhibits adipogenesis of murine 3T3-L1 adipocytes and primary human subcutaneous preadipocytes and these effects are partly mediated by the activation of the AMP-activated protein kinase (AMPK) signaling pathway.

Methods: 3T3-L1 adipocytes and primary human subcutaneous preadipocytes were differentiated using a standard protocol …

The Impact Of Sarcopenic Obesity On Inflammation, Lean Body Mass, And Muscle Strength In Elderly Women, Dahan Da Cunha Nascimento, Samuel Da Cunha Oliveira, Denis Cesar Leite Vieira, Silvana Schwerz Funghetto, Alessandro Oliveira Silva, Renato Valduga, Brad J. Schoenfeld, Jonato Prestes

Publications and Research

Objective: The objective of this study was to apply the newly standardized definition for sarcopenia from the Foundation for the National Institutes of Health (FNIH) and the current definition for obesity to 1) determine the prevalence of sarcopenic obesity (SO) in obese elderly women; 2) compare the muscle strength, lean body mass, and markers of inflammation between obese elderly women with SO and nonsarcopenic obesity (NSO), and 3) elucidate the relation- ship between appendicular lean mass adjusted for body mass index (aLM/BMI) with muscle strength, lean body mass, and obesity indices.

Methods: A total of 64 elderly obese women (age: …

Urban Gardens And Nutrition In Sioux Falls, Sd, Austin Brynjulson

Electronic Theses and Dissertations

With the global population recently surpassing seven and a half billion, questions about feeding the population have emerged. In the past, increased demand for food was addressed through increasing intensification of land use and increasing the area of land under cultivation. Despite these efforts, food insecurity has increased for much of the population over this period, where, according to the USDA, in the U.S. 49.1 million people were food insecure in 2013. Food insecurity in this regard is the lack of access to sufficient, safe, and nutritious food at all times. While the complex global food system may be difficult …

The Effects Of Pre-Pregnancy Tobacco Use On Food Cravings And Weight Gain In Pregnancy, Lauren E. Blau

Legacy Theses & Dissertations (2009 - 2024)

Smoking cessation is associated with greater frequency of food cravings, even when controlling for body mass index. Recent studies have indicated similarities between obese women and women who smoke tobacco in mood states and food craving frequency. This is consistent with the common substrate hypothesis, which postulates that shared neural pathways mediate craving across multiple domains, and could explain why it is common for women attempting to quit smoking to gain weight. Smoking cessation prior to pregnancy is strongly encouraged due to the adverse effects of tobacco use on the developing fetus. Studies have shown that women who quit smoking …

10-Year Time Trends In Patients Undergoing Abdominal Surgery: Do Surgical Site Infection Risks Change Over Time?, Jonathan W. Cotton

MUSC Theses and Dissertations

This study was designed to identify risk factors of SSI over time. We identified several surgeries that were significant for SSI and have changed over time. Obesity was a factor of specific interest. Due to potential under-coding this was a predictive factor, however not as significant as initially anticipated. We were able to identify risk factors and specific groups to concentrate further study or changes in treatment to reduce SSI. There were significant findings over time with each specific surgery type. Surprising were the negative correlation of Charlson Comorbidity score. In addition being black was a protective factor for SSI. …

A Shift Toward A High-Fat Diet In The Current Metabolic Paradigm: A New Perspective, Hunter S. Waldman, Ben M. Krings, Johneric W. Smith, Matthew J. Mcallister

Kinesiology

Objective: Investigations into the relationship between dietary carbohydrate restriction and health are mixed. Current guidelines for nutrition promote low-fat foods and higher carbohydrate consumption for optimal health and weight loss. However, high-fat, low-carbohydrate diets are revealing both intra- and extracellular adaptations that have been shown to elicit favorable cardiometabolic changes associated with obesity. Moreover, dietary fat is associated with higher satiety levels from the hormones adiponectin, leptin, and cholecystokinin. Additionally, insulin responses from high-glycemic carbohydrates are known to alter these pathways, potentially leading to an increase in energy consumption and a possible mechanism for obesity.

Conclusion: There is convincing evidence …

Evaluation Of Barriers For Small-Scale Fruit And Vegetable Growers In Kentucky, Amanda Schroeder Hege

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The food system in the United States has witnessed significant challenges resulting in food security and safety concerns, environmental damage, economic distress, and a decline in our population’s health. While the last fifty years showed a drop in land and workforce dedicated to farming, industrialized farms are producing an overabundance of cheap corn that directly supplies inexpensive, unhealthy foods leading to American’s diets falling short of recommendations for good health, thus contributing to the obesity epidemic. This study utilizes an upstream approach to learn from farmers’ ability to grow good food that promotes healthy people, environments, and communities. Specifically, the …

Effects Of High Fat Exposure On Skeletal Muscle Autophagy And Endoplasmic Reticulum Stress, Adrienne Rose Herrenbruck

Theses and Dissertations--Kinesiology and Health Promotion

Autophagy is a major degradation mechanism, responsible for clearing damaged and dysfunctional organelles, including the endoplasmic reticulum, a structure essential for protein synthesis and myocellular hypertrophy. Alterations in autophagy throughout various tissues of the body have been linked to various negative side effects such as decreased myocellular hypertrophy and insulin resistance. High fat diets lead to changes (both increases and decreases) in autophagy in various tissues throughout the body in a tissue-specific manner.

Skeletal muscle autophagy is decreased in myotubes cultured from obese women, however the mechanism by which this occurs is unknown. As the largest organ system in the …

Utilization Of Web‐Based App To Target Obesogenic Factors In Rural Kentucky Counties With High Rates Of Obesity, Erin M. Casey

Theses and Dissertations--Nutrition and Food Systems

Due to socioeconomic disparities and geographic isolation, rural Kentucky residents bear a greater burden of poor health compared to national averages. Specifically, rural Kentucky residents are at greater risk of becoming obese and suffering from comorbidities of obesity such as type 2 diabetes, hypertension and cardiovascular disease. The purpose of the present study was two-fold. First, we the barriers to nutrition and physical activity unique to rural Kentucky counties which high proportions of obese adults (< 40%) were examined and extrapolated. Second, this information was used to develop a health and wellness app tailored to rural Kentucky counties. The objective was met via a formative assessment regarding causes for obesity in three rural Kentucky counties using focus groups. From these discussions, two major themes arose: barriers to good nutrition and physical activity, and desired web‐app features. From this assessment, FitFaceoff was developed and released into the same counties. Usage and user interaction were assessed using GoogleAnalytics™ software. Analysis revealed poor user liking and unsuccessful implementation of FitFaceoff, however further qualitative research is needed to evaluate poor user reception of FitFaceoff and possible future directions.