Digital Commons Network^™

Weight Status Of Children Aged 2-5 Years Old, Attending A Paediatric Outpatient Clinic And Its Association With Parental Feeding Style And Parental Perceptions Of Weight Status, Aisling Lee, Helen Callaghan, Dara Gallagher Dr, Annette Lalor, Louise Rattigan, Hilary Greaney, Laura Keaver

SURE Journal: Science Undergraduate Research Experience Journal

Background: A child’s weight status can allow health care professionals to assess their developmental growth. A child having a low or high weight for height could be due to an imbalance in nutrient intake occurring. It is important to balance dietary intake and physical activity to maintain a healthy weight status. Excessive consumption of food can lead to an overweight/obese weight status which is linked to non-communicable diseases. Parental feeding style can directly impact a child’s set of eating behaviours. Therefore, parents have a strong influence over a child’s growth pattern. In addition, parental awareness of childhood obesity is reported …

From The Democratic Republic Of The Congo To North Carolina: An Examination Of Chronic Disease Risk, Lauren R. Sastre Dr.

Journal of Refugee & Global Health

Refugees from the Democratic Republic of the Congo are one of the largest refugee groups globally and in the US, however, there is limited research with this group. Therefore, objectives of this study were to examine: 1) obesity and hypertension rates, 2) diet and lifestyle behavior changes, and 3) diet, lifestyle and social factors of obesity and hypertension risk of Congolese refugees in the US. This cross-sectional data collection utilized a survey developed specifically for this project. Clinical and anthropometric measures including height, weight and blood pressure were also obtained. Data analysis included descriptive and regression analysis. Participants (n=48, >18 …

Impacts Of Public Land And Income On Obesity In The United States, Megan Brower, Gracie Carlsen

Student Scholarship - College of Business

This study looked at state public land acreage, average median income, poverty rates, and unemployment rates to analyze the significance of their impact on obesity in the United States. Percentage of public land for each state was gathered from a data overview of 2018, data for the economic factors of influence were from 2017-2019, and obesity rate information was collected from 2019. The hypothesis was that there would be a negative relationship to obesity with public land and average median income; and a positive relationship to obesity with poverty and unemployment rates. This study found there to be a negative …

Assessing Health Risks In Rural Communities Surrounding Zacapa, Guatemala, Kristy Stearns, Oswald Attin

Virginia Journal of Public Health

Purpose: To determine the prevalence of diabetes, obesity, and anemia among Guatemalan adults, as well as the rates of obesity among children in Zacapa, Guatemala. Location, gender, age, personal education level, household daily income, or employment status were examined to determine whether they influence rates of obesity and anemia among adults in Zacapa, Guatemala.

Methods: Community health assessments involved gathering height, weight, body mass index, blood glucose, hemoglobin, and blood pressure measurements from eligible participants. Microsoft Excel 2016 and IBM SPSS Version 23.0 were used to present descriptive statistics and analyze the data using binomial logistic regression tests.

Results/Findings: There …

Breakfast Skipping And Overweight/Obesity In First Grade Primary School Children: A Nationwide Register-Based Study In Iceland, Anita Aanesen, Peter T. Katzmarzyk, Linda Ernstsen

Population and Public Health Science Faculty Publications

Although several studies have revealed an association between skipping breakfast and overweight (OW) or obesity (OB) in older children and adolescents, less is known about that association in younger children. The purpose of our study was to assess the association between skipping breakfast and OW/OB in children in the first grade. The sample included 4360 children (51.5% boys) aged 5.6 to 7.4 years who participated in the annual health examination in Iceland during 2016 and 2017, completed by 91% of all first graders in Iceland. Binary logistic regression analysis with odds ratios (ORs) and 95% confidence intervals (CIs) was used …

Exercise Training Impacts Skeletal Muscle Clock Machinery In Prediabetes, Melissa L. Erickson, H. U.I. Zhang, Jacob T. Mey, John P. Kirwan

Division of Basic Science Faculty Publications

Purpose Disruption of the skeletal muscle molecular clock leads to metabolic disease, whereas exercise may be restorative, leading to improvements in metabolic health. The purpose of this study was to evaluate the effects of a 12-wk exercise intervention on skeletal muscle molecular clock machinery in adults with obesity and prediabetes, and determine whether these changes were related to exercise-induced improvements in metabolic health. Methods Twenty-six adults (age, 66 ± 4.5 yr; body mass index (BMI), 34 ± 3.4 kg·m-2; fasting plasma glucose, 105 ± 15 mg·dL-1) participated in a 12-wk exercise intervention and were fully provided isoenergetic diets. Body composition …

Sensor-Measured Physical Activity Is Associated With Decreased Cardiovascular Disease Risk In African Americans, John A. Bernhart Ph.D., Mph, Ches, Gabrielle M. Turner-Mcgrievy Ph.D., Rd, Sarah Eustis, Mary J. Wilson Phd, Mph, Brent Hutto Msph, Sara Wilcox Phd, Edward A. Frongillo Jr. Ph.D., E. Angela Murphy

Faculty Publications

Introduction: Few studies have examined relationships between sensor-measured physical activity (PA) and cardiovascular disease (CVD) risk among African Americans. This study described relationships between PA and CVD risk in NEW Soul study participants. Methods: Participants completed a dual X-ray absorptiometry scan and measures of blood pressure, waist and hip circumference, height, and weight. Actigraph GTM accelerometers measured moderate to vigorous physical activity (MVPA). We assessed relationships between minutes/day of MVPA and total body fat percent, total lean body mass, total fat mass, total bone mass, total fat distribution, body mass index (BMI), systolic and diastolic blood pressure, and waist-to-hip ratio, …

The Central Melanocortin System And Human Obesity, Yongjie Yang, Yong Xu

Children’s Nutrition Research Center Staff Publications

The prevalence of obesity and the associated comorbidities highlight the importance of understanding the regulation of energy homeostasis. The central melanocortin system plays a critical role in controlling body weight balance. Melanocortin neurons sense and integrate the neuronal and hormonal signals, and then send regulatory projections, releasing anorexigenic or orexigenic melanocortin neuropeptides, to downstream neurons to regulate the food intake and energy expenditure. This review summarizes the latest progress in our understanding of the role of the melanocortin pathway in energy homeostasis. We also review the advances in the identification of human genetic variants that cause obesity via mechanisms that …

Differences In Adolescent Activity And Dietary Behaviors Across Home, School, And Other Locations Warrant Location-Specific Intervention Approaches., Adrian Ortega, Carolina M. Bejarano, Christopher C. Cushing, Vincent S. Staggs, Amy Papa, Chelsea Steel, Robin P. Shook, Debra K. Sullivan, Sarah C. Couch, Terry L. Conway, Brian E. Saelens, Karen Glanz, Lawrence D. Frank, Kelli L. Cain, Jacqueline Kerr, Jasper Schipperijn, James F Sallis, Jordan A. Carlson

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Investigation of physical activity and dietary behaviors across locations can inform "setting-specific" health behavior interventions and improve understanding of contextual vulnerabilities to poor health. This study examined how physical activity, sedentary time, and dietary behaviors differed across home, school, and other locations in young adolescents.

METHODS: Participants were adolescents aged 12-16 years from the Baltimore-Washington, DC and the Seattle areas from a larger cross-sectional study. Participants (n = 472) wore an accelerometer and Global Positioning Systems (GPS) tracker (Mean days = 5.12, SD = 1.62) to collect location-based physical activity and sedentary data. Participants (n = 789) completed 24-h …

Rats Genetically Selected For High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin By Upregulation Of Hepatic Biliverdin Reductase-A (Bvra) And Suppression Of Ugt1a1, Terry D. Hinds Jr., Justin F. Creeden, Darren M. Gordon, Adam C. Spegele, Steven L. Britton, Lauren G. Koch, David E. Stec

Pharmacology and Nutritional Sciences Faculty Publications

Exercise in humans and animals increases plasma bilirubin levels, but the mechanism by which this occurs is unknown. In the present study, we utilized rats genetically selected for high capacity running (HCR) and low capacity running (LCR) to determine pathways in the liver that aerobic exercise modifies to control plasma bilirubin. The HCR rats, compared to the LCR, exhibited significantly higher levels of plasma bilirubin and the hepatic enzyme that produces it, biliverdin reductase-A (BVRA). The HCR also had reduced expression of the glucuronyl hepatic enzyme UGT1A1, which lowers plasma bilirubin. Recently, bilirubin has been shown to activate the peroxisome …

Winning In Weight-Loss: The Interaction Of Conscientiousness And Perceived Autonomy, Jason M. Curtis, Marc Lochbaum

Journal for Sports Neuroscience

ABSTRACT

Background

Understanding determinants for weight-loss is a national priority. Obesity is an epidemic with serious health consequences. Most of today’s obesity and overweight problems are being attributed to poor diets and not enough physical activity. These problems show no signs of slowing down with the behaviors of most Americans. The phenomenon of “The Biggest Loser” (different variants of weight-loss programs that consist of group exercise participation and nutrition therapy to elicit weight-loss, and hopefully behavior change) has spawned many variants in commercial health clubs. This prospectus study examined the direct and interactive or moderated effects of known determinants of …

Β-Cell Function Or Insulin Resistance Was Associated With The Risk Of Type 2 Diabetes Among Women With Or Without Obesity And A History Of Gestational Diabetes, Yuxin Fan, Leishen Wang, Huikun Liu, Shuang Zhang, Huiguang Tian, Yun Shen, Jaakko Tuomilehto, Zhijie Yu, Xilin Yang, Gang Hu, Ming Liu

Population and Public Health Science Faculty Publications

Introduction To evaluate the single association of postpartum β-cell dysfunction and insulin resistance (IR), as well as different combinations of postpartum β-cell dysfunction, IR, obesity, and a history of gestational diabetes mellitus (GDM) with postpartum type 2 diabetes risk. Research design and methods The study included 1263 women with prior GDM and 705 women without GDM. Homeostatic model assessment was used to estimate homeostatic model assessment of β-cell secretory function (HOMA-%β) and homeostatic model assessment of insulin resistance (HOMA-IR). Results Multivariable-adjusted ORs of diabetes across quartiles of HOMA-%β and HOMA-IR were 1.00, 1.46, 2.15, and 6.25 (p trend < 0.001), and 1.00, 2.11, 5.59, and 9.36 (p trend < 0.001), respectively. Women with IR only had the same diabetes risk as women with β-cell dysfunction only. Obesity, together with IR or β-cell dysfunction, had a stronger effect on diabetes risk. This stronger effect was also found for a history of GDM with IR or β-cell dysfunction. Women with three risk factors, including obesity, a history of GDM and β-cell dysfunction/IR, showed the highest ORs of diabetes. Conclusions β-cell dysfunction or IR was significantly associated with postpartum diabetes. IR and β-cell dysfunction, together with obesity and a history of GDM, had the highest ORs of postpartum diabetes risk.

Ameliorative Effects Of Pergamum Harmala Seed Extract On Obese Diabetic Rats, Neveen Magdy, Mohamed Salama, Youssef Alsaedy, Gehad El-Sayed

Mansoura Veterinary Medical Journal

Objective:To explore the potential antidiabetic activity of methanolic extract of Harmal seeds in obese-diabetic rats. Design: Randomized controlled experimental study. Animals: Forty male Sprague Dawley rats. Procedures: The P. harmala seeds methanolic extract was prepared and orally administered at two doses of 150 and 250 mg/kg to two groups of streptozotocin-induced diabetic rats. Two additional control groups were used as healthy control and obese-diabetic control groups. Animals were euthanized after 8 weeks of experimental period, blood and tissue samples were collected. Liver tissue samples were used to determine antioxidant and oxidative stress markers; while those from adipose tissue were used …

The Impact Of Narratives And Active Video Games On Long-Term Moderate-To-Vigorous Physical Activity: A Randomized Controlled Trial Protocol, Dar Alon, Caio Victor Sousa, Tom Baranowski, Tiago V Barreira, Romina Cabrera-Perez, Kelly Chiu, Austin Fernandez, Amy Fleischman, Shirley Huang, Jungyun Hwang, Melanie C Green, I-Min Lee, Kelly Lee, Sarah Lessard, Lynne L Levitsky, Aika Misawa, Farzad Noubary, Ronald Samuels, Kyung Jin Sun, Debbe Thompson, Amy S Lu

Children’s Nutrition Research Center Staff Publications

Background: Although physical activity (PA) has been shown in helping prevent and treat obesity, current PA interventions are still not effective in ameliorating the obesity epidemic. Additional forms of PA need to be investigated to improve PA engagement and outcomes. We hypothesize that pairing a narrative (i.e., story) with an active video game (AVG), a less traditional form of PA, will increase participant engagement in PA. This paper presents the rationale, implementation, and pilot results of a study assessing the effect of narrative's impact on PA and a series of other health outcomes.

Objective: This paper presents the rationale, implementation, …

The Intertwined Relationship Between Malnutrition And Poverty, Faareha Siddiqui, Rehana Salam, Zohra S. Lassi, Jai K. Das

Woman and Child Health

Despite social and economic development, the burden of malnutrition across the globe remains unacceptably high. A vital relationship exists between nutritional status, human capital, and economic standing. Malnutrition adversely affects the physiological and mental capacity of individuals; which in turn hampers productivity levels, making them and their respective countries more susceptible to poverty. A two-way link exists between malnutrition and poverty, creating a vicious cycle with each fueling the other. Malnutrition produces conditions of poverty by reducing the economic potential of the population and likewise, poverty reinforces malnutrition by increasing the risk of food insecurity. The aim of the paper …

Increasing Patient Enrollment In The Move Program At The Va Medical Center: An Evidence-Based Practice Project, Mandy Spiers

Student Scholarly Projects

Practice Problem: This evidence-based practice project aimed to increase patient referrals to the MOVE program by educating providers about the importance and benefit of the Managing Obesity for Veterans Everywhere (MOVE) Program at the Biloxi, Veterans Affairs (VA) Medical Center.

PICOT: In obese, ambulatory care patients, what motivates increased referrals by practitioners to the MOVE Program to decrease BMI compared to the current referral system within two months?

Evidence: There was poor participation in the MOVE Program despite the high number of obese patients at the Biloxi, VA Medical Center. According to the data, only sixty of the 18,000 …

All-Cause Mortality In Metabolically Healthy Individuals Was Not Predicted By Overweight And Obesity, Qiuyue Tian, Anxin Wang, Yingting Zuo, Shuohua Chen, Haifeng Hou, Wei Wang, Shouling Wu, Youxin Wang

Research outputs 2014 to 2021

BACKGROUND

Metabolically healthy obesity (MHO) and metabolically healthy overweight (MH-OW) have been suggested to be important and emerging phenotypes with an increased risk of cardiovascular disease (CVD). However, whether MHO and MH-OW are associated with all-cause mortality remains inconsistent.

METHODS The association of MHO and MH-OW and all-cause mortality was determined in a Chinese community-based prospective cohort study (the Kailuan study), including 93,272 adults at baseline. Data were analyzed from 2006 to 2017. Participants were categorized into 6 mutually exclusive groups, according to BMI and metabolic syndrome (MetS) status. The primary outcome was all-cause death, and accidental deaths were excluded. …

Rodent Models Of Type 2 Diabetes Mellitus, Zaki Tubesha

Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه

Diabetes is a disease characterized by a relative or absolute lack of insulin, leading to hyperglycemia. Due to the high prevalence of diabetic individuals all over the globe, extensive research is being carried out effective to develop more antidiabetic agents and to determine their mechanisms of action. Consequently, a number of diabetic animal models have been developed and improved over the years, of which rodent models are the most thoroughly described. The animal models of type 2 diabetes can be obtained either spontaneously (genetics) or induced by chemicals, dietary, surgical manipulations or by various combinations. In this review my attention …

Identifying, Adapting, And Implementing A Weight Management Program In Rural Primary Care, Gwenndolyn Porter

Theses & Dissertations

Rural adults are at heightened risk for obesity, yet evidence‐based interventions lack consistent translation into clinical practice. This multi-phase study addresses this gap. First, a systematic review and meta-analysis of rural adult weight loss interventions were conducted to assess overall impact. Though few studies reported participant representativeness, meta‐analyses revealed a significant weight reduction among interventions. Second, 10 focus groups were conducted with primary care (PC) staff to determine the feasibility of implementing a weight-management program through PC. Differences in responses among rural, micropolitan, and metropolitan was also assessed. Thematic analyses revealed rural PC currently lacks the capacity to manage patient …

Health Ambassadors: A Model For Engaging Community Leaders To Promote Better Health, Sandra Torres

Master's Projects and Capstones

Obesity continues to be a growing epidemic in the United States. Individuals who live in low-income communities’ face inequities in areas that continue to have adverse and long-lasting consequences. These consequences can extend from economic conditions, social support, and a lack of access to healthy eating choices and physical activity, all of which contribute to higher obesity rates. It is essential to increase opportunities for change in low-income communities and provide ongoing recommendations to policymakers to allocate resources where it is needed. This paper aims to examine a Health Ambassador model in low-income communities tailored to residents in public housing …

Impact Of Sleep Duration, Sleep Quality, And Physical Activity On Obesity Indices Among Adolescents, Sarah Thompson

Theses and Dissertations

Adolescent prevalence of obesity and at-risk WC has continued to rise worldwide. Sleep duration, sleep quality, and physical activity have been hypothesized as contributing factors to this increase. PURPOSE: This study aimed to examine the sleep–obesity relation in adolescents. METHODS: Using data from the 2015-2016 NHANES(n=454; ages 16-18 years), the effect of sleep duration, sleep quality, and MVPA on BMI and WC by gender was analyzed using appropriate sampling weights. RESULTS: Longer sleep duration was associated with increased BMI (β=0.07; 0.065, p<0.05) and WC (β=0.069; 0.13, p<0.05) among males and females. Poor sleep quality was associated with increased BMI among males and females (β= 0.04; 0.08, p< 0.05). A significant main effect was observed across sleep duration, sleep quality and MVPA via multiple regression for both BMI and WC. CONCLUSIONS: For both males and females, BMI and WC were impacted by excessive sleep, poor sleep quality, and low MVPA, with greater associations among males.

The Effects Of Alcohol Consumption On Cardiometabolic Health Outcomes Following Weight Loss In Premenopausal Women With Obesity: A Pilot Randomized Controlled Trial, John W. Apolzan, Robbie A. Beyl, Corby K. Martin, Frank L. Greenway, Ursula White

Clinical Research Faculty Publications

Alcohol (i.e., ethanol) is consumed regularly by much of the adult population; yet, the health effects associated with its use are not well-characterized. Clinical interventions to investigate the effects of moderate alcohol consumption on metabolic outcomes, including adiposity and cardiovascular risk factors, are limited and have yielded conflicting data. In addition, no study has reported the effects of routine alcohol intake during weight loss in a controlled feeding trial. We present the first randomized controlled pilot trial to investigate the effects of moderate alcohol consumption on metabolic outcomes during weight loss in women with obesity. Both groups consumed 30% energy …

Active Transportation And Health: Understanding The Impact Of Transportation-Related Physical Activity On Health, Sina Famili

Civil Engineering Dissertations - Archive

Car-oriented infrastructure in the U.S. leads to physically inactive lifestyles and negative health outcomes. To promote physical activity, public health officials encourage active transportation, namely biking and walking on daily trips. Previous studies proved that both perceived or self-assessed and objective health measures should be used to understand individuals’ health status. Therefore, this study uses the National Household Travel Survey (NHTS) data to understand the associations between perceived health and modal trip features including the number of trips, trip distance, and duration for auto, public transit, walk, and bike trips. Regarding the objective health, this dissertation uses one-week walking activities …

Profound And Redundant Functions Of Arcuate Neurons In Obesity Development, Canjun Zhu, Zhiying Jiang, Yuanzhong Xu, Zhao-Lin Cai, Qingyan Jiang, Yong Xu, Mingshan Xue, Benjamin R Arenkiel, Qi Wu, Gang Shu, Qingchun Tong

Children’s Nutrition Research Center Staff Publications

The current obesity epidemic faces a lack of mechanistic insights. It is known that the acute activity changes of a growing number of brain neurons rapidly alter feeding behaviour; however, how these changes translate to obesity development and the fundamental mechanism underlying brain neurons in controlling body weight remain elusive. Here, we show that chronic activation of hypothalamic arcuate GABAergic (GABA

Paraventricular Hypothalamus Mediates Diurnal Rhythm Of Metabolism, Eun Ran Kim, Yuanzhong Xu, Ryan M Cassidy, Yungang Lu, Yongjie Yang, Jinbin Tian, De-Pei Li, Rachel Van Drunen, Aleix Ribas-Latre, Zhao-Lin Cai, Mingshan Xue, Benjamin R Arenkiel, Kristin Eckel-Mahan, Yong Xu, Qingchun Tong

Children’s Nutrition Research Center Staff Publications

Defective rhythmic metabolism is associated with high-fat high-caloric diet (HFD) feeding, ageing and obesity; however, the neural basis underlying HFD effects on diurnal metabolism remains elusive. Here we show that deletion of BMAL1, a core clock gene, in paraventricular hypothalamic (PVH) neurons reduces diurnal rhythmicity in metabolism, causes obesity and diminishes PVH neuron activation in response to fast-refeeding. Animal models mimicking deficiency in PVH neuron responsiveness, achieved through clamping PVH neuron activity at high or low levels, both show obesity and reduced diurnal rhythmicity in metabolism. Interestingly, the PVH exhibits BMAL1-controlled rhythmic expression of GABA-A receptor γ2 subunit, and dampening …

'It's Common Sense That An Individual Must Eat': Advocating For Food Justice With People With Psychiatric Disabilities Through Photovoice., Lara Carson Weinstein, Mariana Chilton, Renee Turchi, Ann C Klassen, Marianna Lanoue, Alexis Silvero, Leopoldo J Cabassa

Department of Family & Community Medicine Faculty Papers

BACKGROUND: People with SMI have often been excluded in advocacy efforts focused on physical health, health care and health and social policy.

OBJECTIVE: Following a Photovoice project focused on barriers to healthy eating and physical activity in urban neighbourhoods, participant-researchers were invited to present their insights in community advocacy settings. The purpose of this study was to explore the feasibility and participant-researchers' experience of these community advocacy activities.

DESIGN: We held four focus groups with the eight participant-researchers after each community advocacy activity to explore their experience with public speaking, presenting their experiences and advocating.

SETTING AND PARTICIPANTS: People with …

Disrupted Hypothalamic Crh Neuron Responsiveness Contributes To Diet-Induced Obesity, Canjun Zhu, Yuanzhong Xu, Zhiying Jiang, Jin Bin Tian, Ryan M Cassidy, Zhao-Lin Cai, Gang Shu, Yong Xu, Mingshan Xue, Benjamin R Arenkiel, Qingyan Jiang, Qingchun Tong

Children’s Nutrition Research Center Staff Publications

The current obesity epidemic mainly results from high-fat high-caloric diet (HFD) feeding and may also be contributed by chronic stress; however, the neural basis underlying stress-related diet-induced obesity remains unknown. Corticotropin-releasing hormone (CRH) neurons in the paraventricular hypothalamus (PVH), a known body weight-regulating region, represent one key group of stress-responsive neurons. Here, we found that HFD feeding blunted PVH CRH neuron response to nutritional challenges as well as stress stimuli and dexamethesone, which normally produce rapid activation and inhibition on these neurons, respectively. We generated mouse models with the activity of these neurons clamped at high or low levels, both …

Lifestyle Intervention’S Effect And Predictive Value On Weight Loss For University Employees, Elizabeth Wang, Azza H. Ahmed, Pi-Ju Liu, Elizabeth A. Richards

School of Nursing Faculty Publications

Obesity is a costly and pervasive risk factor that requires attention to reduce chronic disease rates. This study evaluated the effect of a lifestyle medicine intervention, Complete Health Improvement Program (CHIP), on reducing weight, blood pressure, lipid levels, and hemoglobin A1c. A secondary aim was to build a preliminary predictive model for computing new participants’ potential weight change from CHIP. We evaluated pre- and post-intervention biometric data of 68 individuals who completed a 10-week CHIP intervention at a Midwestern university clinic. Significant reductions (p < 0.05) were observed in weight, diastolic blood pressure, total cholesterol, low-density lipoprotein, and A1c. Regression analyses indicated that the best linear model for predicting change in weight was a one-predictor model with systolic blood pressure. The CHIP intervention effectively promoted weight loss and meaningful reductions in chronic disease risk factors. Larger samples are needed for future regression analyses to create a more robust linear model.

Breastfeeding And Childhood Obesity: A 12-Country Study, Jian Ma, Yijuan Qiao, Pei Zhao, Wei Li, Peter T. Katzmarzyk, Jean Philippe Chaput, Mikael Fogelholm, Rebecca Kuriyan, Estelle V. Lambert, Carol Maher, Jose Maia, Victor Matsudo, Timothy Olds, Vincent Onywera, Olga L. Sarmiento, Martyn Standage, Mark S. Tremblay, Catrine Tudor-Locke, Gang Hu

Population and Public Health Science Faculty Publications

This study aimed to examine the association between breastfeeding and childhood obesity. A multinational cross-sectional study of 4,740 children aged 9–11 years was conducted from 12 countries. Infant breastfeeding was recalled by parents or legal guardians. Height, weight, waist circumference, and body fat were obtained using standardized methods. The overall prevalence of obesity, central obesity, and high body fat were 12.3%, 9.9%, and 8.1%, respectively. After adjustment for maternal age at delivery, body mass index (BMI), highest maternal education, history of gestational diabetes, gestational age, and child's age, sex, birth weight, unhealthy diet pattern scores, moderate-to-vigorous physical activity, sleeping, and …

Metabolic Benefits Of Plant-Based N-3 Polyunsaturated Fatty Acids On Brown Thermogenesis, Kyung Ho Park

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

There are two essential fatty acids for humans, a-linolenic acid (ALA) and linoleic acid (LA), which should be taken from foods to maintain health. Once incorporated into cells, ALA and LA, which are omega-3 poly unsaturated fatty acid (n-3 PUFA) and n-6 PUFA respectively, undergo elongation and desaturation to generate longer and more unsaturated fatty acids influencing inflammation and immunological responses. Numerous studies showed a dietary reduction of n-6/n-3 PUFA ratio improves cardiovascular health, inflammation, and insulin resistance. Fish oil, the main resource for n-3 PUFA, is shown to increase these health benefits. In our lab, we investigated the efficacy …