Digital Commons Network^™

Machine Learning Models For Pancreatic Cancer Survival Prediction: A Multi-Model Analysis Across Stages And Treatments Using The Surveillance, Epidemiology, And End Results (Seer) Database, Aditya Chakraborty, Mohan D. Pant

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background: Pancreatic cancer is among the most lethal malignancies, with poor prognosis and limited survival despite treatment advances. Accurate survival modeling is critical for prognostication and clinical decision-making. This study had three primary aims: (1) to determine the best-fitting survival distribution among patients diagnosed and deceased from pancreatic cancer across stages and treatment types; (2) to construct and compare predictive risk classification models; and (3) to evaluate survival probabilities using parametric, semi-parametric, non-parametric, machine learning, and deep learning methods for Stage IV patients receiving both chemotherapy and radiation. Methods: Using data from the SEER database, parametric models (Generalized Extreme Value, …

Nexus: Network Exploration For Exploiting Unsafe Sequences In Multi-Turn Llm Jailbreaks, Javad Rafiei Asl, Sidhant Narula, Mohammad Ghasemigol, Eduardo Blanco, Daniel Takabi

School of Cybersecurity Faculty Publications

Large Language Models (LLMs) have revolutionized natural language processing, yet remain vulnerable to jailbreak attacks—particularly multi-turn jailbreaks that distribute malicious intent across benign exchanges, thereby bypassing alignment mechanisms. Existing approaches often suffer from limited exploration of the adversarial space, rely on hand-crafted heuristics, or lack systematic query refinement. We propose NEXUS (Network Exploration for eXploiting Unsafe Sequences), a modular framework for constructing, refining, and executing optimized multi-turn attacks. NEXUS comprises: (1) ThoughtNet, which hierarchically expands a harmful intent into a structured semantic network of topics, entities, and query chains; (2) a feedback-driven Simulator that iteratively refines and prunes these chains …

Qos-Aware Link Adaptation For Beyond 5g Networks: A Deep Reinforcement Learning Approach, Ali Parsa, Neda Moghim, Sachin Shetty

Center for Secure and Intelligent Critical Systems (CSICS) Publications

Modern wireless communication systems face increasingly complex challenges due to rapidly changing channel conditions and the growing diversity of application-specific Quality of Service (QoS) requirements. Traditional link adaptation mechanisms primarily aim to maximize throughput and often lack the flexibility to support emerging applications, such as Extended Reality (XR) and Virtual Reality (VR), which demand simultaneous guarantees for high data rates, ultra low latency, and high reliability. These stringent and multidimensional QoS needs call for more intelligent and adaptive solutions. In this paper, we propose QDRLLA (QoS-aware Deep Reinforcement Learning-based Link Adaptation), a novel framework that employs deep reinforcement learning to …

Predicting Food Prices In Kenya Using Machine Learning: A Hybrid Model Approach With Xgboost And Gradient Boosting, Benard O. Ogol, Evans Omondi, John Olukuru, Betsy Muriithi, Kennedy Senagi

All Peer-Reviewed Publications

Introduction: Food price volatility continues to be a significant concern in Kenya's economic development, posing challenges to the country's economic stability. Methodology: This study examines the application of machine learning methods, employing a hybrid approach that combines XGBoost and gradient boosting, to predict food prices in Kenya. The food prices data from the World Food Programme, covering the period from January 2006 to September 2024, as well as currency exchange rates data from the Central Bank of Kenya in US dollars (USD) and inflation rates data, were collated and preprocessed to be ready for analytics and machine learning. The augmented …

Machine Learning For Computer-Aided Diagnostics From Complex Medical Images, Afsah Saleem

Theses: Doctorates and Masters

Machine learning has significantly transformed medical image analysis in the current age of artificial intelligence offering vast potential in improving disease diagnosis and management. Cardiovascular diseases (CVDs) are among the leading cause of global mortality, emphasizing the need for early detection for effective intervention and prevention. Abdominal Aortic Calcification (AAC) is an early indicator and contributor to Atherosclerotic Cardiovascular Diseases (ASCVDs) and is commonly assessed through imaging modalities such as computed tomography (CT), X-rays, and Dual-energy X-ray Absorptiometry (DXA). Among these, lateral spine DXA scans, commonly used for osteoporosis screening, offer a cost-effective and low-radiation opportunity for opportunistic CVD risk …

Anomaly Detection Of Seasonal Vessel Activity, Travis Rybicki

Theses: Doctorates and Masters

Monitoring maritime traffic is essential for ensuring the safety of vessels, safeguarding transported goods or persons, and preventing illicit or hazardous activity at sea. Increasingly, researchers have explored data-driven approaches to model expected vessel behaviour and detect deviations or anomalies. These anomalies—such as course deviations, unauthorised area entries, or unexpected operational patterns—can indicate emergencies, regulatory breaches, or unlawful intent. Data broadcast by vessels provides a valuable resource for such analyses; however, the inherent complexity and context-dependency of maritime behaviour present persistent modelling challenges. One critical yet underutilised factor in this context is seasonality. For certain vessel types, for example, fishing …

Coldstartcpi: Induced-Fit Theory-Guided Dti Predictive Model With Improved Generalization Performance, Qichang Zhao, Haochen Zhao, Linyuan Gao, Kai Zheng, Yajie Li, Qiao Ling, Jing Tang, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Predicting compound-protein interactions (CPIs) plays a crucial role in drug discovery. Traditional methods, based on the key-lock theory and rigid docking, often fail with novel compounds and proteins due to their inability to account for molecular flexibility and the high sparsity of CPI data. Here, we introduce ColdstartCPI, a framework inspired by induced-fit theory, which leverages unsupervised pre-training features and a Transformer module to learn both compound and protein characteristics. ColdstartCPI treats proteins and compounds as flexible molecules during inference, aligning with biological insights. It outperforms state-of-the-art sequence-based models, particularly for unseen compounds and proteins, and shows strong generalization capability …

Optiselect And Enshap: Integrating Machine Learning And Game Theory For Ischemic Stroke Prediction, Pritam Chakraborty, Anjan Bandyopadhyay, Sricheta Parul, Sujata Swain, Partha Sarathy Banerjee, Tapas Si, Hong Qin, Saurav Mallik

Computer Science Faculty Publications

Stroke analysis using game theory and machine learning techniques. The study investigates the use of the Shapley value in predictive ischemic brain stroke analysis. Initially, preference algorithms identify the most important features in various machine learning models, including logistic regression, K-nearest neighbor, decision tree, support vector machine (linear kernel), support vector machine ( RBF kernel), neural networks, etc. For each sample, the top 3, 4, and 5 features are evaluated and selected to evaluate their performance. The Shapley value method was used to rank the models using their best four features based on their predictive capabilities. As a result, better-performing …

Benchmarking Batch-Effect Correction Methods Towards The Construction Of A Triple-Negative Breast Cancer Cell Atlas, Peter Scheible, Amy H. Tang, Jing He, Jiangwen Sun

Computer Science Faculty Publications

Triple-negative breast cancer (TNBC) requires detailed cellular mapping given its aggressive nature, immense tumor heterogeneity and genetic diversity. We integrated 156,794 cells from six scRNA-seq datasets—including tumors, metastases, and cell lines—to build a TNBC scRNA cell atlas, focusing on batch effect mitigation while maintaining biological and molecular details. Preprocessing f ilters noise, normalizes data, and leverages PCA for integration readiness. We utilized scANVI, a semi-supervised tool, to align datasets, preserving TNBC’s complex tumor heterogeneity via marker annotations [1]. UMAPs demonstrate biological clustering in integrated data, contrasted with datasetdriven unintegrated patterns. Assessments verifying effective batch correction. This method aligns with NASA’s …

Human Perception Of Ai Capabilities At Classifying Perturbed Roadway Signs, Katherine R. Garcia, Jing Chen, Yanru Xiao, Scott Mishler, Cong Wang, Bin Hu

Computer Science Faculty Publications

Artificial Intelligence (AI) is crucial to numerous functions required for driving automation systems, including the computer vision techniques used to detect the roadway environment and make real-time decisions. However, the images used as inputs to the AI system may be maliciously perturbed, or manipulated, causing the AI system to make an incorrect classification. In this study, we examined humans’ perception of the AI’s computer vision capability of classifying various road sign images, including the original images, images with two different types of malicious attacks, and images that are scrambled randomly at the pixel level. Our results showed that participants rated …

Ai For Nuclear Physics: The Exclaim Project, S. Liuti, D. Adams, M. Boër, G. W. Chern, M. Cuic, M. Engelhardt, G. R. Goldstein, B. Kriesten, Y. Li, H. W. Lin, M. Sievert, D. Sivers

Computer Science Faculty Publications

An overview of the recent activity of the newly funded EXCLusives with AI and Machine learning (EXCLAIM) collaboration is presented. The main goal of the collaboration is to develop a framework to implement AI and machine learning techniques in problems emerging from the phenomenology of high energy exclusive scattering processes from nucleons and nuclei, maximizing the information that can be extracted from various sets of experimental data, while implementing theoretical constraints from lattice QCD. A specific perspective embraced by EXCLAIM is to use the methods of theoretical physics to understand the working of ML, beyond its standardized applications to physics …

Icu-Length Of Stay Prediction On Electronic Health Records Using Graph Neural Networks And Homogeneous Similarity Graphs, Ahmad F. Al Musawi, Pratip Rana, Sibtanu Raha, Joshua Braunstein, William C. Sleeman Iv, Rishabh Kapoor, Preetam Ghosh

Computer Science Faculty Publications

Predicting the length of stay (LoS) is important for hospital administration, as it helps allocate proper resources, such as bed management and hospital staffing. Patients' Electronic Health Records (EHRs) contain highly relevant data for LoS prediction; however, their integration and effective use in predictive modeling for accurately estimating LoS remain challenging. To address this, we propose a homogeneous Graph Neural Network (GNN)-based framework for predicting LoS. This method employs a comprehensive data fusion strategy based on the hospital Visit-based Similarity Graph (VSG), which integrates diverse multi-modal clinical features into a coherent, homogeneous graph representation. Next, this VSG is fed into …

Meta’S Ai Bias To What Extent Do Meta's Algorithmic Processes For Classifying And Processing Information Related To Acts Of Racism Impact Fairness, Bias, And Social Justice Across Its Platforms?, Shanique Foster

Electronic Theses and Dissertations 2020 - Present

Algorithmic processing and classification of racism-related content have become increasingly prevalent across Meta's platforms. While these algorithms aim to create safer online environments, their effectiveness and impact on fairness remain understudied. This research examines how Meta's algorithmic processes for classifying racist content affect fairness, bias, and social justice across Facebook, Instagram, and WhatsApp.

Using qualitative research methodology, the study conducted focus groups with diverse platform users to understand their experiences with content moderation. The research also analyzed theoretical frameworks related to algorithmic bias, fairness metrics, and social justice in digital spaces.

Key findings revealed significant variations in algorithmic effectiveness across …

Neural And Computational Approach To Understanding Environmental Modulation Of Behavioral Identity In Zebrafish, John W. Hageter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Organisms rely on behavior for survival. Animals engage in behaviors that allow for feeding, mating, exploring and navigating their environment among others. Necessary for these behaviors to develop are the environmental factors and underlying circuitry which make behavior possible. Specifically, how the environment guides underlying neural circuitry to develop unique facets or phenotypes of a larger behavior are key to understanding why unique behaviors exist. In this thesis, I build foundational evidence for determining these mechanisms through the use of the zebrafish local search behavior. This is a behavior that zebrafish employ following the loss of environmental illumination where they …

Augmentation And Hybridization Of Conventional Forms Of Process Control With Advanced Control Methods, Daniel Paul Beahr

Graduate Theses, Dissertations, and Problem Reports (ETD)

Within the last decade in the field of process control, there has developed a distinct gap between the technological advancements of today and the well-established theory that has preceded it. This is most evident where the novel developments and structures often outpace the necessary guarantees and strong foundation required to ensure the possibility of widespread adoption. Therefore, the goals of this work are to broadly integrate those novel advanced control methods into the field of process control in such a way to increase the applicability and encourage implementation.

The first portion of this work seeks to further explore the nature …

Data-Driven Gradient Optimization For Field Emission Management In A Superconducting Radio-Frequency Linac, S. Goldenberg, K. Ahammed, A. Carpenter, J. Li, R. Suleiman, C. Tennant

Electrical & Computer Engineering Faculty Publications

Field emission can cause significant problems in superconducting radio-frequency linear accelerators (linacs). When cavity gradients are pushed higher, radiation levels within the linacs may rise exponentially, causing degradation of many nearby systems. This research aims to utilize machine learning with uncertainty quantification to predict radiation levels at multiple locations throughout the linacs and ultimately optimize cavity gradients to reduce field emission-induced radiation while maintaining the total linac energy gain necessary for the experimental physics program. The optimized solutions show over 40% reductions for both neutron and gamma radiation from the standard operational settings.

Land Target Detection Algorithm In Remote Sensing Images Based On Deep Learning, Wenyi Hu, Xiaomeng Jiang, Jiawei Tian, Shitong Ye, Shan Liu

Electrical & Computer Engineering Faculty Publications

Remote sensing technology plays a crucial role across various sectors, such as meteorological monitoring, city planning, and natural resource exploration. A critical aspect of remote sensing image analysis is land target detection, which involves identifying and classifying land-based objects within satellite or aerial imagery. However, despite advancements in both traditional detection methods and deep-learning-based approaches, detecting land targets remains challenging, especially when dealing with small and rotated objects that are difficult to distinguish. To address these challenges, this study introduces an enhanced model, YOLOv5s-CACSD, which builds upon the YOLOv5s framework. Our model integrates the channel attention (CA) mechanism, CARAFE, and …

Analyzing Visual Attention In Virtual Crime Scene Investigations Using Eye-Tracking And Vr: Insights For Cognitive Modeling, Wen-Chao Yang, Chih-Hung Shih, Jiajun Jiang, Sergio Pallas Enguita, Chung-Hao Chen

Electrical & Computer Engineering Faculty Publications

Understanding human perceptual strategies in high-stakes environments, such as crime scene investigations, is essential for developing cognitive models that reflect expert decision-making. This study presents an immersive experimental framework that utilizes virtual reality (VR) and eye-tracking technologies to capture and analyze visual attention during simulated forensic tasks. A 360° panoramic crime scene, constructed using the Nikon KeyMission 360 camera, was integrated into a VR system with HTC Vive and Tobii Pro eye-tracking components. A total of 46 undergraduate students aged 19 to 24–23, from the National University of Singapore in Singapore and 23 from the Central Police University in Taiwan—participated …

A Novel Intelligent Thermal Feedback Framework For Electric Motor Protection In Embedded Robotic Systems, Mohamed Shili, Salah Hammedi, Hicham Chaoui, Khaled Nouri

Electrical & Computer Engineering Faculty Publications

As robotic systems advance in autonomy and sophistication while being used in uncertain environments, the challenge of building reliable and robust electric motors that are embedded into robotic systems has never been a more important engineering problem. Thermal distress caused by extended operation or excessive loading can negatively affect a motor’s performance and efficiency and lead to catastrophic hardware failure. This paper proposes a novel intelligent control framework that includes real-time thermal feedback for hybrid electric motors that are embedded into robotic systems. The framework relies on adaptive control techniques and lightweight machine learning techniques to estimate internal motor temperatures …

Advances In Battery Modeling And Management Systems: A Comprehensive Review Of Techniques, Challenges, And Future Perspectives, Seyed Saeed Madani, Yasmin Shabeer, Ananthu Shibu Nair, Michael Fowler, Satyam Panchal, Carlos Ziebert, Hicham Chaoui, Shi Xue Dou, Khay See, Saad Mekhilef, Françios Allard

Electrical & Computer Engineering Faculty Publications

Energy storage systems (ESSs) and electric vehicle (EV) batteries depend on battery management systems (BMSs) for their longevity, safety, and effectiveness. Battery modeling is crucial to the operation of BMSs, as it enhances temperature control, fault detection, and state estimation, thereby maximizing efficiency and preventing malfunctions. This paper thoroughly examines the most recent advancements in battery and BMS modeling, including data-driven, thermal, and electrochemical methods. Advanced modeling approaches are explored, including physics-based models that incorporate mechanical stress and aging effects, as well as artificial intelligence (AI)-driven state estimation. New technologies that facilitate data-driven decision-making, real-time monitoring, and simplified systems include …

Enhancing Cyber Situational Awareness Through Dynamic Adaptive Symbology: The Dass Framework, Nicholas Macrino, Sergio Pallas Enguita, Chung-Hao Chen

Electrical & Computer Engineering Faculty Publications

The static nature of traditional military symbology, such as MIL-STD-2525D, hinders effective real-time threat detection and response in modern cybersecurity operations. This research introduces the Dynamic Adaptive Symbol System (DASS), a novel framework enhancing cyber situational awareness in military and enterprise environments. The DASS addresses static symbology limitations by employing a modular Python 3.10 architecture that uses machine learning-driven threat detection to dynamically adapt symbol visualization based on threat severity and context. Empirical testing assessed the DASS against a MIL-STD-2525D baseline using active cybersecurity professionals. Results show that the DASS significantly improves threat identification rates by 30% and reduces response …

Ai-Based Steganography Method To Enhance The Information Security Of Hidden Messages In Digital Images, Nhi Do Ngoc Huynh, Jiajun Jiang, Chung-Hao Chen, Wen-Chao Yang

Electrical & Computer Engineering Faculty Publications

With the increasing sophistication of Artificial Intelligence (AI), traditional digital steganography methods face a growing risk of being detected and compromised. Adversarial attacks, in particular, pose a significant threat to the security and robustness of hidden information. To address these challenges, this paper proposes a novel AI-based steganography framework designed to enhance the security of concealed messages within digital images. Our approach introduces a multi-stage embedding process that utilizes a sequence of encoder models, including a base encoder, a residual encoder, and a dense encoder, to create a more complex and secure hiding environment. To further improve robustness, we integrate …

Automating The Amino Acid Identification In Elliptical Dichroism Spectrometer With Machine Learning, Ridhanya Sree Balamurugan, Yusuf Asad, Tommy Gao, Dharmakeerthi Nawarathna, Umamaheswara Rao Tida, Dali Sun

Electrical & Computer Engineering Faculty Publications

Amino acid identification is crucial across various scientific disciplines, including biochemistry, pharmaceutical research, and medical diagnostics. However, traditional methods such as mass spectrometry require extensive sample preparation and are time-consuming, complex and costly. Therefore, this study presents a pioneering Machine Learning (ML) approach for automatic amino acid identification by utilizing the unique absorption profiles from an Elliptical Dichroism (ED) spectrometer. Advanced data preprocessing techniques and ML algorithms to learn patterns from the absorption profiles that distinguish different amino acids were investigated to prove the feasibility of this approach. The results show that ML can potentially revolutionize the amino acid analysis …

T3-Ciders: Fostering A Community Of Practice In Ci-And Data Enabled Cybersecurity Research Through A Train-The-Trainer Program, Wirawan Purwanto, Mohan Yang, Peng Jiang, Masha Sosonkina

Electrical & Computer Engineering Faculty Publications

We present a training program named T³-CIDERS, the Train- The-Trainer approach to fostering cyberinfrastructure (CI)- and Data-Enabled Research in CyberSecurity. T³-CIDERS is a train-the-trainer program for advanced cyberinfrastructure (CI) skills that is designed to be synergistic with research, teaching, and learning activities in cybersecurity and cyber-related disciplines. The participants, termed 'future trainers' (FTs), are trained in effective instructional design and CI hands-on materials from DeapSECURE, developed in a previous CyberTraining program. T³-CIDERS aims to enhance cybersecurity research and education through broader adoption of advanced CI techniques such as artificial intelligence, big data, parallel programming, and platforms like high-performance computing (HPC) …

Detecting Anomalous Srf Cavity Behavior With Unsupervised Learning, Hal Ferguson, Jiang Li, Adam Carpenter, Chris Tennant, Dillon Thomas, Dennis Turner

Electrical & Computer Engineering Faculty Publications

We present an unsupervised learning framework for detecting anomalous superconducting radio-frequency (SRF) cavity behavior at the Continuous Electron Beam Accelerator Facility (CEBAF), emphasizing its initial performance and effectiveness. Key to the system’s success was the development of data acquisition systems (DAQs) that capture fast-sampled, information-rich signals, essential for detecting transient effects. The approach involves creating daily cavity-specific models using principal component analysis to handle variations in rf signal behavior and mitigate performance degradation from data drift. This unsupervised method eliminates the need for expensive labeling by continuously updating models with recent data. Deployed and operational for 3 months before a …

Point Cloud-Based Diffusion Models For The Electron-Ion Collider, Jack Y. Araz, Vinicius Mikuni, Felix Ringer, Nobuo Sato, Fernando Torales Acosta, Richard Whitehill

Physics Faculty Publications

At high-energy collider experiments, generative models can be used for a wide range of tasks, including fast detector simulations, unfolding, searches of physics beyond the Standard Model, and inference tasks. In particular, it has been demonstrated that score-based diffusion models can generate high-fidelity and accurate samples of jets or collider events. This work expands on previous generative models in three distinct ways. First, our model is trained to generate entire collider events, including all particle species with complete kinematic information. We quantify how well the model learns event-wide constraints such as the conservation of momentum and discrete quantum numbers. We …

Association Between Risk Factors And Major Cancers: Explainable Machine Learning Approach, Xiayuan Huang, Shushun Ren, Xinyue Mao, Sirui Chen, Elle Chen, Yuqi He, Yun Jiang

Faculty Research, Scholarly, and Creative Activity

Background: Cancer is a life-threatening disease and a leading cause of death worldwide, with an estimated 611,000 deaths and over 2 million new cases in the United States in 2024. The rising incidence of major cancers, including among younger individuals, highlights the need for early screening and monitoring of risk factors to manage and decrease cancer risk. Objective: This study aimed to leverage explainable machine learning models to identify and analyze the key risk factors associated with breast, colorectal, lung, and prostate cancers. By uncovering significant associations between risk factors and these major cancer types, we sought to enhance the …

Fuel Consumption Prediction Using Bayesian Neural Networks, Syarifah Diana Permai, Jurike V. Moniaga, Zener Sukra Lie, Ferry Jie

Research outputs 2022 to 2026

Transportation is one of the necessities of life. Because humans need transportation to move from one location to another. Transportation requires fuel. On the other hand, fuel consumption is important and must be controlled. This is because fuel can come from both renewable and non-renewable energy sources, depending on the type and process of its formation. Several factors influence the fuel efficiency of a car, including the type of engine, vehicle weight, aerodynamics, driving habits, and other vehicle conditions. This research aims to predict car fuel consumption and identify the factors that affect fuel consumption. Several Machine Learning and Statistical …

Protocol For An Integrative Meta-Analysis Of The Application Of Machine Learning Algorithms In The Prediction Of Chronic Disease Risks And Outcomes, Ebenezer Afrifa-Yamoah, Emmanuel Peprah-Yamoah, Enoch Odame Anto, Victor Opoku-Yamoah, Eric Adua

Research outputs 2022 to 2026

Background: Precise risk prediction of chronic diseases is essential for effective preventive care and management. Machine learning (ML) is a promising avenue to enhance chronic disease risk prediction; however, a comprehensive assessment of ML performance across various chronic diseases, populations, and health settings is needed. Methods: This meta-analysis aims to synthesize evidence on the performance of ML techniques for predicting the risks and outcomes of chronic diseases. A literature search was conducted through PubMed, Web of Science, Scopus, Science Direct, Medline, and Embase. Studies applying ML techniques to predict chronic disease risks or outcomes and reporting performance metrics were included. …

Machine Learning-Based Seismic Response Forecasting Using Feature Mapping Algorithms And Scientometric Analysis Of Nailed Vertical Excavation In A Soil Mass, Surya Muthukumar, Dhanya Sathyan, Premjith B, Sanjay Kumar Shukla

Research outputs 2022 to 2026

Seismic analysis often involves significant uncertainty and requires detailed observations. The traditional approaches are constrained by unclear mechanisms and imprecise models to predict the stability of geostructures. The research gap between the accuracy of observed and predicted values can be bridged by employing artificial intelligence-based machine learning (ML) models. The seismic displacement of the nailed soil wall obtained from experimental studies were assessed using suitable ML approaches. Laboratory studies revealed that the critical acceleration was increased by 32% on the inclusion of nails of reinforcement length to excavation height ratio (L/H) to 0.6, and by 17% when the (L/H) was …