Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Physical Sciences and Mathematics (1344)
- Computer Sciences (1034)
- Engineering (813)
- Artificial Intelligence and Robotics (391)
- Medicine and Health Sciences (373)
-
- Computer Engineering (275)
- Life Sciences (273)
- Electrical and Computer Engineering (234)
- Social and Behavioral Sciences (225)
- Medical Specialties (178)
- Data Science (152)
- Medical Sciences (121)
- Statistics and Probability (103)
- Business (98)
- Bioinformatics (82)
- Law (75)
- Civil and Environmental Engineering (72)
- Databases and Information Systems (67)
- Operations Research, Systems Engineering and Industrial Engineering (67)
- Mechanical Engineering (66)
- Theory and Algorithms (65)
- Environmental Sciences (63)
- Biomedical Engineering and Bioengineering (62)
- Biomedical Informatics (57)
- Mathematics (55)
- Arts and Humanities (53)
- Earth Sciences (52)
- Physics (52)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (51)
- Other Computer Engineering (51)
- Institution
-
- Rochester Institute of Technology (170)
- The Texas Medical Center Library (118)
- Brigham Young University (113)
- Old Dominion University (111)
- University of Nebraska - Lincoln (86)
-
- Singapore Management University (82)
- Air Force Institute of Technology (73)
- San Jose State University (69)
- Technological University Dublin (69)
- Portland State University (58)
- University of Texas at Arlington (58)
- Florida Atlantic University (56)
- Louisiana State University (56)
- TÜBİTAK (54)
- Utah State University (49)
- University of South Carolina (45)
- City University of New York (CUNY) (44)
- Chapman University (43)
- University of Kentucky (43)
- New Jersey Institute of Technology (41)
- University of Louisville (41)
- Boise State University (39)
- University of South Florida (39)
- University of Texas Rio Grande Valley (39)
- Zayed University (39)
- Mississippi State University (38)
- Missouri University of Science and Technology (38)
- Thomas Jefferson University (37)
- California Polytechnic State University, San Luis Obispo (34)
- University of Arkansas, Fayetteville (32)
- Publication Year
- Publication
-
- Theses and Dissertations (259)
- Theses (197)
- Faculty Publications (89)
- Electronic Theses and Dissertations (83)
- Dissertations (70)
-
- Faculty, Staff and Student Publications (59)
- Research Collection School Of Computing and Information Systems (59)
- Turkish Journal of Electrical Engineering and Computer Sciences (47)
- Master's Theses (43)
- All Works (37)
- Electronic Theses and Dissertations 2020 - Present (37)
- Faculty, Staff and Students Publications (36)
- Dissertations and Theses (34)
- Faculty Research, Scholarly, and Creative Activity (33)
- Articles (30)
- USF Tampa Graduate Theses and Dissertations (28)
- Boise State University Theses and Dissertations (26)
- Dissertations, Theses, and Capstone Projects (24)
- Faculty Scholarship (24)
- Browse all Theses and Dissertations (23)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (23)
- LSU Doctoral Dissertations (23)
- Master's Projects (22)
- Baghdad Science Journal (21)
- Doctoral Dissertations (21)
- Electrical & Computer Engineering Faculty Publications (21)
- Computer Science and Engineering Dissertations - Archive (19)
- Graduate Theses and Dissertations (19)
- SMU Data Science Review (19)
- Conference papers (18)
- Publication Type
- File Type
Articles 841 - 870 of 3123
Full-Text Articles in Entire DC Network
Anti-Phishing Approach For Iot System In Fog Networks Based On Machine Learning Algorithms, Mahmoud Gad Awwad, Mohamed M. Ashour, El Said A. Marzouk, Eman Abdelhalim
Anti-Phishing Approach For Iot System In Fog Networks Based On Machine Learning Algorithms, Mahmoud Gad Awwad, Mohamed M. Ashour, El Said A. Marzouk, Eman Abdelhalim
Mansoura Engineering Journal
As the Internet of Things (IoT) continues to expand, ensuring the security and privacyِ of IoT systems becomes increasingly critical. Phishing attacks pose a significant threat to IoT devices and can lead to unauthorized access, data breaches, and compromised functionality. In this paper, we propose an anti-phishing approach for IoT systems in fog networks that leverages machine learning algorithms, including a .fusion with deep learning techniques We explore the effectiveness of eleven traditional machine learning algorithms combined with deep learning in detecting and preventing phishing attacks in IoT systems. By utilizing a diverse range of algorithms, we aim to enhance …
Gt-Ches And Dycon: Improved Classification For Human Evolutionary Systems, Joseph S. Johnson
Gt-Ches And Dycon: Improved Classification For Human Evolutionary Systems, Joseph S. Johnson
Theses and Dissertations
The purpose of this work is to rethink the process of learning in human evolutionary systems. We take a sober look at how game theory, network theory, and chaos theory pertain specifically to the modeling, data, and training components of generalization in human systems. The value of our research is three-fold. First, our work is a direct approach to align machine learning generalization with core behavioral theories. We made our best effort to directly reconcile the axioms of these heretofore incompatible disciplines -- rather than moving from AI/ML towards the behavioral theories while building exclusively on AI/ML intuition. Second, this …
Detecting Anomalies In Time Series Using Kernel Density Approaches, Robin Frehner, Kesheng Wu, Alexander Sim, Jinoh Kim
Detecting Anomalies In Time Series Using Kernel Density Approaches, Robin Frehner, Kesheng Wu, Alexander Sim, Jinoh Kim
Faculty Publications
This paper introduces a novel anomaly detection approach tailored for time series data with exclusive reliance on normal events during training. Our key innovation lies in the application of kernel-density estimation (KDE) to scrutinize reconstruction errors, providing an empirically derived probability distribution for normal events post-reconstruction. This non-parametric density estimation technique offers a nuanced understanding of anomaly detection, differentiating it from prevalent threshold-based mechanisms in existing methodologies. In post-training, events are encoded, decoded, and evaluated against the estimated density, providing a comprehensive notion of normality. In addition, we propose a data augmentation strategy involving variational autoencoder-generated events and a smoothing …
Exploring The Challenges Of Diagnosing Thyroid Disease With Imbalanced Data And Machine Learning: A Systematic Literature Review, Dhekre Saber Saleh, Mohd Shahizan Othman
Exploring The Challenges Of Diagnosing Thyroid Disease With Imbalanced Data And Machine Learning: A Systematic Literature Review, Dhekre Saber Saleh, Mohd Shahizan Othman
Baghdad Science Journal
Thyroid disease is a common disease affecting millions worldwide. Early diagnosis and treatment of thyroid disease can help prevent more serious complications and improve long-term health outcomes. However, thyroid disease diagnosis can be challenging due to its variable symptoms and limited diagnostic tests. By processing enormous amounts of data and seeing trends that may not be immediately evident to human doctors, Machine Learning (ML) algorithms may be capable of increasing the accuracy with which thyroid disease is diagnosed. This study seeks to discover the most recent ML-based and data-driven developments and strategies for diagnosing thyroid disease while considering the challenges …
Investigating Customer Churn In Banking: A Machine Learning Approach And Visualization App For Data Science And Management, Pahul Preet Singh, Fahim Islam Anik, Rahul Senapati, Arnav Sinha, Nazmus Sakib, Eklas Hossain
Investigating Customer Churn In Banking: A Machine Learning Approach And Visualization App For Data Science And Management, Pahul Preet Singh, Fahim Islam Anik, Rahul Senapati, Arnav Sinha, Nazmus Sakib, Eklas Hossain
Electrical and Computer Engineering Faculty Publications and Presentations
Customer attrition in the banking industry occurs when consumers quit using the goods and services offered by the bank for some time and, after that, end their connection with the bank. Therefore, customer retention is essential in today’s extremely competitive banking market. Additionally, having a solid customer base helps attract new consumers by fostering confidence and a referral from a current clientele. These factors make reducing client attrition a crucial step that banks must pursue. In our research, we aim to examine bank data and forecast which users will most likely discontinue using the bank’s services and become paying customers. …
Weakly Supervised Attention-Based Recognition Under Spectral, Turbulence, And Resource Variations, Kshitij Naresh Nikhal
Weakly Supervised Attention-Based Recognition Under Spectral, Turbulence, And Resource Variations, Kshitij Naresh Nikhal
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
While supervised optimization paradigms are ubiquitous across diverse recognition systems, the risk of over-fitting and increasing bias have limited their applicability.
This dissertation focuses on unsupervised learning—learning without precisely curated data—and argues that unsupervised learning methods can enable both discriminability and generalizability. Through the use of attention-based machine learning and advanced clustering, unsupervised methods are able to focus on fine-grained information in images without any explicit supervision. The dissertation introduces a domain-bridging framework for tasks like cross-spectrum matching and long-range recognition, utilizing intra-domain clustering and inter-domain matching to generate pseudo-labels. Additionally, a hash-based network is proposed to accelerate the search …
Voice Synthesis Improvement By Machine Learning Of Natural Prosody, Joseph Kane, Michael N. Johnstone, Patryk Szewczyk
Voice Synthesis Improvement By Machine Learning Of Natural Prosody, Joseph Kane, Michael N. Johnstone, Patryk Szewczyk
Research outputs 2022 to 2026
Since the advent of modern computing, researchers have striven to make the human–computer interface (HCI) as seamless as possible. Progress has been made on various fronts, e.g., the desktop metaphor (interface design) and natural language processing (input). One area receiving attention recently is voice activation and its corollary, computer-generated speech. Despite decades of research and development, most computer-generated voices remain easily identifiable as non-human. Prosody in speech has two primary components—intonation and rhythm—both often lacking in computer-generated voices. This research aims to enhance computer-generated text-to-speech algorithms by incorporating melodic and prosodic elements of human speech. This study explores a novel …
A Multi-Appointment Patient Scheduling System With Machine Learning And Optimization, Ying Han, Marina E. Johnson, Xiaojun Shan, Mohammad Khasawneh
A Multi-Appointment Patient Scheduling System With Machine Learning And Optimization, Ying Han, Marina E. Johnson, Xiaojun Shan, Mohammad Khasawneh
Department of Information Management and Business Analytics Faculty Scholarship and Creative Works
Appointment scheduling is critical to increasing resource utilization and operational performance in various industry domains, especially healthcare. Costs to care for several serious diseases are projected to grow due to the aging population and rising drug prices. Thus, there is an urgent need for efficient operational planning and scheduling to reduce expenses. This research explores ways to effectively schedule outpatient chemotherapy visits with multiple appointments requiring different resources. The study aims to assess the impact of patient no-shows and individual stochastic appointment durations in scheduling performance and determine if overbooking is viable to mitigate the adverse effects of patient no-shows. …
A Machine Learning Approach For Multipath Characterization And Mitigation Using Chipshape Observations, Sean A. L. Quiterio
A Machine Learning Approach For Multipath Characterization And Mitigation Using Chipshape Observations, Sean A. L. Quiterio
Theses and Dissertations
Multipath continues to be a significant error source in satellite navigation. Recent solutions with Neural Networks (NN) model the effects of multipath on the autocorrelation function to predict errors in the Delay Lock Loop (DLL). Chipshape correlation provides a detailed look into the spreading code transitions in the time domain. It is useful in applications such as Signal Quality Monitoring (SQM) and is much more sensitive to multipath than autocorrelation. This research proposes NN models that each predict pseudorange or carrier range errors due to multipath by monitoring the chipshape correlation output. For a simulation with 50 MHz precorrelation bandwidth …
Improving Rogue Radio Emitter Detection Using Siamese Networks, Mason Wright
Improving Rogue Radio Emitter Detection Using Siamese Networks, Mason Wright
Theses and Dissertations
Radio Frequency Fingerprinting (RFF) is the process of creating discerning signatures of emitted radio signals, most often with the goal of identifying specific devices again in the future. The security benefits of this task are intended to build upon current software-based authentication by making use of multi-factor authentication (MFA), but the related task of being able to reject unwanted emitters is limited. This paper presents a Siamese network trained on two different extracted fingerprints of raw Wi-Fi signals, along with a verifier to perform classification and rogue device detection. It was found that fingerprints using the Distortion Reconstruction (DR) technique …
Bayesian Augmentation Of Object Detection Algorithms To Enhance Object Classification Stability, Taylor D. Markham
Bayesian Augmentation Of Object Detection Algorithms To Enhance Object Classification Stability, Taylor D. Markham
Theses and Dissertations
Neural networks, despite their prowess in computer vision, often exhibit "flickering". Flickering occurs when networks fail to maintain consistent object representation across frames, leading to inaccurate and inconsistent output. This problem is particularly critical in mission-surety applications where reliable object recognition is crucial. This research presents a novel approach that combines existing object detection and tracking algorithms like YOLO and SORT with a Bayesian backend model. This Bayesian backend incorporates probabilistic reasoning to analyze the network's confidence in its predictions and infer the most likely object identity across multiple frames, effectively reducing flickering and enhancing robustness.
Federated Analysis Of Wearables Data For United States Air Force Mental And Physical Readiness, Sung Yong O
Federated Analysis Of Wearables Data For United States Air Force Mental And Physical Readiness, Sung Yong O
Theses and Dissertations
This thesis investigates the use of machine learning and deep learning models within a federated learning framework to predict physical and mental readiness in military personnel, using wearable technology data. The collaboration with the 711th Human Performance Wing’s STRONG Lab highlights the importance of readiness as emphasized by the National Defense and Security Strategies. The study evaluates various predictive models, incorporating federated learning to ensure data privacy and security in healthcare systems. By analyzing a comprehensive dataset, the research aims to contribute to military readiness enhancement through technological advancements, supporting health and wellness initiatives to bolster the effectiveness of military …
A Random Forest-Based Q-Learning Algorithm: Toward Interpretable Artificial Intelligence, Victor R. Rae
A Random Forest-Based Q-Learning Algorithm: Toward Interpretable Artificial Intelligence, Victor R. Rae
Theses and Dissertations
A growing demand exists for interpretable artificial intelligence models, leading to extensive research efforts to enhance the explainability and transparency of policies generated by reinforcement learning (RL) methods. This research develops random forest-based RL algorithms as a logical progression in this academic pursuit. The algorithms are evaluated using three standard benchmark environments from OpenAI gym — CartPole, MountainCar, and LunarLander — and compared to implementations of the Deep Q-learning Network (DQN) and Double DQN (DDQN) algorithms for various metrics, including performance, robustness, efficiency, and interpretability. The random forest-based algorithms exhibit superior performance to both neural network-based algorithms in two out …
Machine Learning Predictions Of Electricity Transfers Between Balancing Authorities In The Carolinas, Victoria Groleau
Machine Learning Predictions Of Electricity Transfers Between Balancing Authorities In The Carolinas, Victoria Groleau
Theses and Dissertations
Climate change through reduced streamflow, increased temperatures, and other factors impacts the efficiency of energy generation systems. The United States electric grid is comprised of a large network of balancing authorities engaged in trading electricity to maintain balance between supply and demand. The generation of electricity, a pivotal component of this balance, is impacted by climate change and weather variability as well as the growing demand for energy. Several hydro climatological factors such as streamflow, air temperature, and wind speed significantly influence the efficiency of power plant electricity generation. Due to the exchange of electricity between balancing authorities, impacts to …
Artificial Intelligence And Perception: An Empirical Study, Anthony J. Neil
Artificial Intelligence And Perception: An Empirical Study, Anthony J. Neil
Theses and Dissertations
This thesis investigates the impact of adjusting artificial intelligence explainability levels’ outputs on user perception. The overarching study extends within the Explainable Artificial Intelligence (XAI) domain. It examines a spectrum of variables, including performance, cognizance, familiarity, transparency, system bias, and the overall impact of AI, to understand their collective and individual effects that enable effective professional use in an organization. The study aims to illuminate the relationship between the degree of explainability provided by large language models such as ChatGPT, Bard, and Bing AI and the performance of these models when tasked with XAI adjustments.
Sensor-Based Vehicle Classification Using Machine Learning, Luke Mcfadden
Sensor-Based Vehicle Classification Using Machine Learning, Luke Mcfadden
Theses and Dissertations
This research investigates the classification of vehicles into heavy and light categories using acoustic, seismic, and magnetic sensor data. The effectiveness of using frequency domain data and classical machine learning techniques, is compared with the effectiveness of using time-series data and neural networks. The primary aim in doing so was to understand if modern neural network architectures could effectively remove the need for more traditional frequency based signals processing. A significant deliverable of this thesis was the feature importance determined for each of the three phenomenological types found within the data (acoustic, seismic, and magnetic). By analyzing the importance of …
The Impact Of Artificial Intelligence And Machine Learning On Organizations Cybersecurity, Mustafa Abdulhussein
The Impact Of Artificial Intelligence And Machine Learning On Organizations Cybersecurity, Mustafa Abdulhussein
Doctoral Dissertations and Projects
As internet technology proliferate in volume and complexity, the ever-evolving landscape of malicious cyberattacks presents unprecedented security risks in cyberspace. Cybersecurity challenges have been further exacerbated by the continuous growth in the prevalence and sophistication of cyber-attacks. These threats have the capacity to disrupt business operations, erase critical data, and inflict reputational damage, constituting an existential threat to businesses, critical services, and infrastructure. The escalating threat is further compounded by the malicious use of artificial intelligence (AI) and machine learning (ML), which have increasingly become tools in the cybercriminal arsenal. In this dynamic landscape, the emergence of offensive AI introduces …
Exploring Important Factors In Predicting Heart Disease Based On Ensemble- Extra Feature Selection Approach, Howida Abubaker, Farkhana Muchtar, Alif Ridzuan Khairuddin, Ahmad Najmi Amerhaider Nuar, Zuriahati Mohd Yunos, Carolyn Salimun
Exploring Important Factors In Predicting Heart Disease Based On Ensemble- Extra Feature Selection Approach, Howida Abubaker, Farkhana Muchtar, Alif Ridzuan Khairuddin, Ahmad Najmi Amerhaider Nuar, Zuriahati Mohd Yunos, Carolyn Salimun
Baghdad Science Journal
Heart disease is a significant and impactful health condition that ranks as the leading cause of death in many countries. In order to aid physicians in diagnosing cardiovascular diseases, clinical datasets are available for reference. However, with the rise of big data and medical datasets, it has become increasingly challenging for medical practitioners to accurately predict heart disease due to the abundance of unrelated and redundant features that hinder computational complexity and accuracy. As such, this study aims to identify the most discriminative features within high-dimensional datasets while minimizing complexity and improving accuracy through an Extra Tree feature selection based …
Endoscopic Hyperspectral Imaging System To Discriminate Tissue Characteristics In Tissue Phantom And Orthotopic Mouse Pancreatic Tumor Model, Na Eun Mun, Thi Kim Chi Tran, Dong Hui Park, Jin Hee Im, Jae Il Park, Thanh Dat Le, Young Jin Moon, Seong-Young Kwon, Su Woong Yoo
Endoscopic Hyperspectral Imaging System To Discriminate Tissue Characteristics In Tissue Phantom And Orthotopic Mouse Pancreatic Tumor Model, Na Eun Mun, Thi Kim Chi Tran, Dong Hui Park, Jin Hee Im, Jae Il Park, Thanh Dat Le, Young Jin Moon, Seong-Young Kwon, Su Woong Yoo
Faculty, Staff and Student Publications
In this study, we developed an endoscopic hyperspectral imaging (eHSI) system and evaluated its performance in analyzing tissues within tissue phantoms and orthotopic mouse pancreatic tumor models. Our custom-built eHSI system incorporated a liquid crystal tunable filter. To assess its tissue discrimination capabilities, we acquired images of tissue phantoms, distinguishing between fat and muscle regions. The system underwent supervised training using labeled samples, and this classification model was then applied to other tissue phantom images for evaluation. In the tissue phantom experiment, the eHSI effectively differentiated muscle from fat and background tissues. The precision scores regarding fat tissue classification were …
Predicting Forage Provision Of Grasslands Across Climate Zones By Hyperspectral Measurements, F. A. Männer, J. Muro, J. Ferner, S. Schmidtlein, A. Linstädter
Predicting Forage Provision Of Grasslands Across Climate Zones By Hyperspectral Measurements, F. A. Männer, J. Muro, J. Ferner, S. Schmidtlein, A. Linstädter
IGC Proceedings (1977-2023)
The potential of grasslands’ fodder production is a crucial management measure, while its quantification is still laborious and costly. Remote sensing technologies, such as hyperspectral field measurements, enable fast and non-destructive estimation. However, such methods are still limited in transferability to other locations or climatic conditions. With this study, we aim to predict forage nutritive value, quantity, and energy yield from hyperspectral canopy reflections of grasslands across three climate zones. We took hyperspectral measurements with a field spectrometer from grassland canopies in temperate, tropical and semi-arid grasslands, and analyzed corresponding biomass samples for their quantity (BM), metabolizable energy content (ME) …
A Comprehensive Patient-Specific Prediction Model For Temporomandibular Joint Osteoarthritis Progression, Najla Al Turkestani, Tengfei Li, Jonas Bianchi, Marcela Gurgel, Juan Prieto, Hina Shah, Erika Benavides, Fabiana Soki, Yuji Mishina, Margherita Fontana, Arvind Rao, Hongtu Zhu, Lucia Cevidanes
A Comprehensive Patient-Specific Prediction Model For Temporomandibular Joint Osteoarthritis Progression, Najla Al Turkestani, Tengfei Li, Jonas Bianchi, Marcela Gurgel, Juan Prieto, Hina Shah, Erika Benavides, Fabiana Soki, Yuji Mishina, Margherita Fontana, Arvind Rao, Hongtu Zhu, Lucia Cevidanes
Pacific Faculty Work
Temporomandibular joint osteoarthritis (TMJ OA) is a prevalent degenerative disease characterized by chronic pain and impaired jaw function. The complexity of TMJ OA has hindered the development of prognostic tools, posing a significant challenge in timely, patient-specific management. Addressing this gap, our research employs a comprehensive, multidimensional approach to advance TMJ OA prognostication. We conducted a prospective study with 106 subjects, 74 of whom were followed up after 2 to 3 y of conservative treatment. Central to our methodology is the development of an innovative, open-source predictive modeling framework, the Ensemble via Hierarchical Predictions through Nested cross-validation tool (EHPN). This …
Strategies To Combine 3d Vasculature And Brain Cta With Deep Neural Networks: Application To Lvo, Uma M Lal-Trehan Estrada, Arnau Oliver, Sunil A Sheth, Xavier Lladó, Luca Giancardo
Strategies To Combine 3d Vasculature And Brain Cta With Deep Neural Networks: Application To Lvo, Uma M Lal-Trehan Estrada, Arnau Oliver, Sunil A Sheth, Xavier Lladó, Luca Giancardo
Faculty, Staff and Student Publications
Automated tools to detect large vessel occlusion (LVO) in acute ischemic stroke patients using brain computed tomography angiography (CTA) have been shown to reduce the time for treatment, leading to better clinical outcomes. There is a lot of information in a single CTA and deep learning models do not have an obvious way of being conditioned on areas most relevant for LVO detection, i.e., the vasculature structure. In this work, we compare and contrast strategies to make convolutional neural networks focus on the vasculature without discarding context information of the brain parenchyma and propose an attention-inspired strategy to encourage this. …
Implications Of Lithium-Ion Cell Temperature Estimation Methods For Intelligent Battery Management And Fast Charging Systems, Ehab Bayoumi
Implications Of Lithium-Ion Cell Temperature Estimation Methods For Intelligent Battery Management And Fast Charging Systems, Ehab Bayoumi
Mechanical Engineering
This article examines in depth the most recent thermal testing techniques for lithium-ion batteries (LIBs). Temperature estimation circuits can be divided into six divisions based on modeling and calculation methods, including electrochemical computational modeling, equivalent electric circuit modeling (EECM), machine learning (ML), digital analysis, direct impedance measurement, and magnetic nanoparticles as a base. Complexity, accuracy, and computational cost-based EECM circuits are feasible. The accuracy, usability, and adaptability of diagrams produced using ML have the potential to be very high. However, both cannot anticipate low-cost integrated BMS live due to their high computational costs. An appropriate solution might be a hybrid …
Longitudinal Single-Cell Transcriptional Dynamics Throughout Neurodegeneration In Sca1, Leon Tejwani, Neal G Ravindra, Changwoo Lee, Yubao Cheng, Billy Nguyen, Kimberly Luttik, Luhan Ni, Shupei Zhang, Logan M Morrison, John Gionco, Yangfei Xiang, Jennifer Yoon, Hannah Ro, Fatema Haidery, Rosalie M Grijalva, Eunwoo Bae, Kristen Kim, Regina T Martuscello, Harry T Orr, Huda Y Zoghbi, Hayley S Mcloughlin, Laura P W Ranum, Vikram G Shakkottai, Phyllis L Faust, Siyuan Wang, David Van Dijk, Janghoo Lim
Longitudinal Single-Cell Transcriptional Dynamics Throughout Neurodegeneration In Sca1, Leon Tejwani, Neal G Ravindra, Changwoo Lee, Yubao Cheng, Billy Nguyen, Kimberly Luttik, Luhan Ni, Shupei Zhang, Logan M Morrison, John Gionco, Yangfei Xiang, Jennifer Yoon, Hannah Ro, Fatema Haidery, Rosalie M Grijalva, Eunwoo Bae, Kristen Kim, Regina T Martuscello, Harry T Orr, Huda Y Zoghbi, Hayley S Mcloughlin, Laura P W Ranum, Vikram G Shakkottai, Phyllis L Faust, Siyuan Wang, David Van Dijk, Janghoo Lim
Duncan NRI Faculty and Staff Publications
Neurodegeneration is a protracted process involving progressive changes in myriad cell types that ultimately results in the death of vulnerable neuronal populations. To dissect how individual cell types within a heterogeneous tissue contribute to the pathogenesis and progression of a neurodegenerative disorder, we performed longitudinal single-nucleus RNA sequencing of mouse and human spinocerebellar ataxia type 1 (SCA1) cerebellar tissue, establishing continuous dynamic trajectories of each cell population. Importantly, we defined the precise transcriptional changes that precede loss of Purkinje cells and, for the first time, identified robust early transcriptional dysregulation in unipolar brush cells and oligodendroglia. Finally, we applied a …
Automating Selective Area Electron Diffraction Phase Identification Using Machine Learning, Nathaniel Tomczak, Jennifer Carter
Automating Selective Area Electron Diffraction Phase Identification Using Machine Learning, Nathaniel Tomczak, Jennifer Carter
Faculty Scholarship
Selective area electron diffraction (SAED) patterns can provide valuable insight into the structure of a material. However, the manual identification of collected patterns can be a significant bottleneck in the overall phase classification workflow. In this work, we utilize the recent advances in computer vision and machine learning (ML) to automate the indexing of SAED patterns. The performance of six different ML algorithms is demonstrated using metallic plutonium-zirconium alloys. The most successful approach trained a neural network (NN) to make a classification of the phase and zone axis, and then utilized a second NN to synthesize multiple independent predictions of …
Self-Optimizing Feature Generation Via Categorical Hashing Representation And Hierarchical Reinforcement Crossing, Wangyang Ying, Dongjie Wang, Kunpeng Liu, Leilei Sun, Yanjie Fu
Self-Optimizing Feature Generation Via Categorical Hashing Representation And Hierarchical Reinforcement Crossing, Wangyang Ying, Dongjie Wang, Kunpeng Liu, Leilei Sun, Yanjie Fu
Computer Science Faculty Publications and Presentations
Feature generation aims to generate new and meaningful features to create a discriminative representation space. A generated feature is meaningful when the generated feature is from a feature pair with inherent feature interaction. In the real world, experienced data scientists can identify potentially useful feature-feature interactions, and generate meaningful dimensions from an exponentially large search space in an optimal crossing form over an optimal generation path. But, machines have limited human-like abilities. We generalize such learning tasks as self-optimizing feature generation. Self-optimizing feature generation imposes several under-addressed challenges on existing systems: meaningful, robust, and efficient generation. To tackle these challenges, …
Accelerating Elastic Property Prediction In Fe-C Alloys Through Coupling Of Molecular Dynamics And Machine Learning, Sandesh Risal, Navdeep Singh, Yan Yao, Li Sun, Samprash Risal, Weihang Zhu
Accelerating Elastic Property Prediction In Fe-C Alloys Through Coupling Of Molecular Dynamics And Machine Learning, Sandesh Risal, Navdeep Singh, Yan Yao, Li Sun, Samprash Risal, Weihang Zhu
Pacific Faculty Work
The scarcity of high-quality data presents a major challenge to the prediction of material properties using machine learning (ML) models. Obtaining material property data from experiments is economically cost-prohibitive, if not impossible. In this work, we address this challenge by generating an extensive material property dataset comprising thousands of data points pertaining to the elastic properties of Fe-C alloys. The data were generated using molecular dynamic (MD) calculations utilizing reference-free Modified embedded atom method (RF-MEAM) interatomic potential. This potential was developed by fitting atomic structure-dependent energies, forces, and stress tensors evaluated at ground state and finite temperatures using ab-initio. Various …
Sigma Leverages Protein Structural Information To Predict The Pathogenicity Of Missense Variants, Hengqiang Zhao, Huakang Du, Sen Zhao, Zefu Chen, Yaqi Li, Kexin Xu, Bowen Liu, Xi Cheng, Wen Wen, Guozhuang Li, Guilin Chen, Zhengye Zhao, Guixing Qiu, Deciphering Disorders Involving Scoliosis & Comorbidities (Disco) Study, Pengfei Liu, Terry Jianguo Zhang, Zhihong Wu, Nan Wu
Sigma Leverages Protein Structural Information To Predict The Pathogenicity Of Missense Variants, Hengqiang Zhao, Huakang Du, Sen Zhao, Zefu Chen, Yaqi Li, Kexin Xu, Bowen Liu, Xi Cheng, Wen Wen, Guozhuang Li, Guilin Chen, Zhengye Zhao, Guixing Qiu, Deciphering Disorders Involving Scoliosis & Comorbidities (Disco) Study, Pengfei Liu, Terry Jianguo Zhang, Zhihong Wu, Nan Wu
Faculty, Staff and Students Publications
Leveraging protein structural information to evaluate pathogenicity has been hindered by the scarcity of experimentally determined 3D protein. With the aid of AlphaFold2 predictions, we developed the structure-informed genetic missense mutation assessor (SIGMA) to predict missense variant pathogenicity. In comparison with existing predictors across labeled variant datasets and experimental datasets, SIGMA demonstrates superior performance in predicting missense variant pathogenicity (AUC = 0.933). We found that the relative solvent accessibility of the mutated residue contributed greatly to the predictive ability of SIGMA. We further explored combining SIGMA with other top-tier predictors to create SIGMA+, proving highly effective for variant pathogenicity prediction …
Performance Of Automated Machine Learning In Predicting Outcomes Of Pneumatic Retinopexy, Arina Nisanova, Arefeh Yavary, Jordan Deaner, Ferhina Ali, Priyanka Gogte, Richard Kaplan, Kevin Chen, Eric Nudleman, Dilraj Grewal, Meenakashi Gupta, Jeremy Wolfe, Michael Klufas, Glenn Yiu, Iman Soltani, Parisa Emami-Naeini
Performance Of Automated Machine Learning In Predicting Outcomes Of Pneumatic Retinopexy, Arina Nisanova, Arefeh Yavary, Jordan Deaner, Ferhina Ali, Priyanka Gogte, Richard Kaplan, Kevin Chen, Eric Nudleman, Dilraj Grewal, Meenakashi Gupta, Jeremy Wolfe, Michael Klufas, Glenn Yiu, Iman Soltani, Parisa Emami-Naeini
Wills Eye Hospital Papers
PURPOSE: Automated machine learning (AutoML) has emerged as a novel tool for medical professionals lacking coding experience, enabling them to develop predictive models for treatment outcomes. This study evaluated the performance of AutoML tools in developing models predicting the success of pneumatic retinopexy (PR) in treatment of rhegmatogenous retinal detachment (RRD). These models were then compared with custom models created by machine learning (ML) experts.
DESIGN: Retrospective multicenter study.
PARTICIPANTS: Five hundred and thirty nine consecutive patients with primary RRD that underwent PR by a vitreoretinal fellow at 6 training hospitals between 2002 and 2022.
METHODS: We used 2 AutoML …
Self-Consistent Phonon Calculations And Quartic Anharmonic Lattice Thermal Conductivity In 2d Ins Monolayer, Eesha Andharia, Hind Alqurashi, Abhiyan Pandit, Bothina Hamad
Self-Consistent Phonon Calculations And Quartic Anharmonic Lattice Thermal Conductivity In 2d Ins Monolayer, Eesha Andharia, Hind Alqurashi, Abhiyan Pandit, Bothina Hamad
Physics Faculty Publications and Presentations
Low lattice thermal conductivity (κl) is a crucial factor for higher figure-of merit and hence the efficiency of thermoelectric generators. There are several reports on intrinsically low κl values in two-dimensional (2D) van der Waals materials using density functional theory and molecular dynamics simulations. In general, phonon dispersions are studied at absolute zero temperature using the finite-displacement approach within harmonic approximations. In addition, the κl is calculated using the third-order cubic interatomic force constants (IFCs) by solving the Boltzmann transport equation for phonons. In these calculations, we use quartic IFCs to solve self-consistent phonon equations …