Digital Commons Network^™

Getting The Gist Of A Schwannoma, Rishabh Gulati, Joshua A. Hanson, Gulshan Parasher, Daniel Castresana

Pathology Research and Scholarship

A small subepithelial esophageal lesion was seen 21 cm from the incisors in an otherwise unremarkable examination. Subsequent upper-EUS examination revealed a 14 mm by 21 mm well-circumscribed, hypoechoic lesion originating from the muscularis propria (layer 4). The initial EUS impression was suggestive of a GI stromal tumor, however, examination of EUS-guided fine-needle biopsy specimens showed a haphazard arrangement of spindle cells in a fibrotic stoma.

Heparin-Induced Thrombocytopenia Associated With Collection Of Hematopoietic Progenitor Cells By Apheresis, Jay S. Raval, Yara A. Park, Irina Perjar, Marshall A. Mazepa, Benjamin G. Vincent, Alice D. Ma, Marian A. Rollins-Raval

Pathology Research and Scholarship

Heparin-induced thrombocytopenia (HIT) can occur following exposure to heparin and is characterized by thrombocytopenia with increased risk for thrombosis. This condition is mediated by formation of immunoglobulin G antibodies against platelet factor 4/heparin complexes that can subsequently lead to platelet activation. Herein, we detail the clinical and laboratory findings, treatments, and outcomes of two patients who developed HIT and thrombosis after undergoing collection of hematopoietic progenitor cells by apheresis (HPC-A) for autologous HPC transplant. Given that heparin may be used during HPC-A collections, these cases emphasize the importance of prompt consideration of HIT in patients that develop thrombocytopenia and thrombosis …

A Multicenter Evaluation Of A Sample To Answer Real-Time Pcr Assay For Toxigenic C. Difficile In Symptomatic Subjects, Preeti Pancholi, Steve Young, R Widen, Suzane Silbert, B Schmitt, R Dunn, A Drain, S A. Weissfeld

Pathology Research and Scholarship

We evaluated the performance of the Luminex ARIES® C. difficile Assay on 984 stool specimens prospectively collected from patients being tested for CDI at 4 clinical laboratories in the United States. Results were compared to direct and enriched toxigenic culture. Positive percent agreement (PPA) of the ARIES® C. difficile Assay was 98.1% versus direct toxigenic culture, and sensitivity versus direct plus enriched toxigenic culture was 90.5%. Negative percent agreement (NPA) of the ARIES® C. difficile Assay against direct culture was 92.6%, and specificity versus direct plus enriched toxigenic culture was 95.8%. The ARIES® C. difficile Assay was also compared to …

A Head-To-Head Comparison Of The Efficacy And Safety Of Ixekizumab And Adalimumab In Biological-Naïve Patients With Active Psoriatic Arthritis: 24-Week Results Of A Randomised, Open-Label, Blinded-Assessor Trial., Philip Mease, Josef S Smolen, Frank Behrens, Peter Nash, Soyi Liu Leage, Lingnan Li, Hasan Tahir, Melinda Gooderham, Eswar Krishnan, Hong Liu-Seifert, Paul Emery, Sreekumar G Pillai, Philip S Helliwell

Articles, Abstracts, and Reports

OBJECTIVES: To compare efficacy and safety of ixekizumab (IXE) to adalimumab (ADA) in biological disease-modifying antirheumatic drug-naïve patients with both active psoriatic arthritis (PsA) and skin disease and inadequate response to conventional synthetic disease-modifying antirheumatic drug (csDMARDs).

METHODS: Patients with active PsA were randomised (1:1) to approved dosing of IXE or ADA in an open-label, head-to-head, blinded assessor clinical trial. The primary objective was to evaluate whether IXE was superior to ADA at week 24 for simultaneous achievement of a ≥50% improvement from baseline in the American College of Rheumatology criteria (ACR50) and a 100% improvement from baseline in the …

Safety And Efficacy Of Tocilizumab In The Treatment Of Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia: A Retrospective Cohort Study, Atul Patel, Kinjal Shah, Mitkumar Dharsandiya, Ketan Patel, Tushar Patel, Mukesh Patel, Tea Reljic, Ambuj Kumar

All publications

Background: Cytokine release storm (CRS) in severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) is thought to be the cause for organ damage and death which is independent of the actual viral burden. Tocilizumab (TCZ), an interleukin-6 receptor antagonist, is approved for the treatment of CRS. We describe the efficacy and safety of TCZ in SARS CoV-2 pneumonia. Methods: This retrospective study was conducted at a tertiary care hospital from April 20 2020 to May 21 2020. The primary endpoint was the cumulative incidence of a composite of either need for admission to the intensive care unit (ICU) with invasive mechanical …

Development And Validation Of A Model For Individualized Prediction Of Hospitalization Risk In 4,536 Patients With Covid-19, Lara Jehi, Xinge Ji, Alex Milinovich, Serpil Erzurum, Amy Merlino, Steve Gordon, James B. Young, Michael W. Kattan

All publications

Background: Coronavirus Disease 2019 is a pandemic that is straining healthcare resources, mainly hospital beds. Multiple risk factors of disease progression requiring hospitalization have been identified, but medical decision-making remains complex.

Objective: To characterize a large cohort of patients hospitalized with COVID-19, their outcomes, develop and validate a statistical model that allows individualized prediction of future hospitalization risk for a patient newly diagnosed with COVID-19.

Design: Retrospective cohort study of patients with COVID-19 applying a least absolute shrinkage and selection operator (LASSO) logistic regression algorithm to retain the most predictive features for hospitalization risk, followed by validation in a temporally …

Implementation Of A Medical Student-Run Telemedicine Program For Medications For Opioid Use Disorder During The Covid-19 Pandemic, Marcus Castillo, Brianna Conte, Sam Hinkes, Megan Mathew, C J Na, Ainhoa Norindr, David P. Serota, David W. Forrest, Amar R. Deshpande, Tyler S. Bartholomew, Hansel E. Tookes

All publications

Objectives: The COVID-19 pandemic led to the closure of the IDEA syringe services program medical student-run free clinic in Miami, Florida. In an effort to continue to serve the community of people who inject drugs and practice compassionate and non-judgmental care, the students transitioned the clinic to a model of TeleMOUD (medications for opioid use disorder). We describe development and implementation of a medical student-run telemedicine clinic through an academic medical center-operated syringe services program.

Methods: Students advertised TeleMOUD services at the syringe service program on social media and created an online sign-up form. They coordinated appointments and interviewed patients …

Statewide Implementation Of Virtual Perinatal Home Visiting During Covid-19, Jennifer Marshall, Laura Kihlström, Acadia Buro, Vidya Chandran, Concha Prieto, Rafaella Stein-Elger, Keryden Koeut-Futch, Allison Parish, Katie Hood

All publications

Purpose: This evaluation describes efforts taken by MIECHV administrators and staff during the pandemic using data collected from 60 MIECHV staff surveys and nine statewide weekly focus groups.

Description: The Florida Maternal, Infant and Early Childhood Home Visiting (MIECHV) Initiative funds perinatal home visiting for pregnant women and families with infants throughout the state. Florida MIECHV has shown resilience to disasters and times of crises in the past, while generating a culture of adaptation and continuous quality improvement among local implementing agencies. Florida MIECHV responded to the COVID-19 pandemic crisis within the first few days of the first reported case …

Acute Encephalopathy With Elevated Csf Inflammatory Markers As The Initial Presentation Of Covid-19, Shelli Farhadian, Laura R. Glick, Chantal B. F. Vogels, Jared Thomas, Jennifer Chiarella, Arnau Casanovas-Massana, Jing Zhou, Camila Odio, Pavithra Vijayakumar, Bertie Geng, John Fournier, Santos Bermejo, Joseph R. Fauver, Tara Alpert, Anne L. Wyllie, Cynthia Turcotte, Matthew Steinle, Patrick Paczkowski, Charles Dela Cruz, Craig Wilen, Albert I. Ko, Sean Mackay, Nathan D. Grubaugh, Serena Spudich, Lydia Aoun Barakat

Journal Articles: Epidemiology

BACKGROUND: COVID-19 is caused by the severe acute respiratory syndrome virus SARS-CoV-2. It is widely recognized as a respiratory pathogen, but neurologic complications can be the presenting manifestation in a subset of infected patients.

CASE PRESENTATION: We describe a 78-year old immunocompromised woman who presented with altered mental status after witnessed seizure-like activity at home. She was found to have SARS-CoV-2 infection and associated neuroinflammation. In this case, we undertake the first detailed analysis of cerebrospinal fluid (CSF) cytokines during COVID-19 infection and find a unique pattern of inflammation in CSF, but no evidence of viral neuroinvasion.

CONCLUSION: Our findings …

Motor Vehicle Fatalities During Memorial Day Weekends, 1981-2016, Yuni Tang, Kendra Ratnapradipa, Henry Xiang, Motao Zhu

Journal Articles: Epidemiology

OBJECTIVE: Motor vehicle crashes are a leading cause of injury death in the United States, and Memorial Day weekend is one of six holiday periods with an increased number of motor vehicle fatalities in the United States. However, few motor vehicle fatality comparisons were made between Memorial Day weekend and non-holiday periods. Our aims were to determine which day(s) during the holiday had highest motor vehicle fatality risk compared to non-holiday travel and to identify potential risk factors.

RESULTS: Of 43,457 traffic fatalities studied, 15,292 (35%) occurred during the holiday, with Saturday being deadliest but Monday having highest odds of …

Us-County Level Variation In Intersecting Individual, Household And Community Characteristics Relevant To Covid-19 And Planning An Equitable Response: A Cross-Sectional Analysis, Taylor Chin, Rebecca Kahn, Ruoran Li, Jarvis T. Chen, Nancy Krieger, Caroline O. Buckee, Satchit Balsari, Mathew V. Kiang

All publications

Objectives: To illustrate the intersections of, and intercounty variation in, individual, household and community factors that influence the impact of COVID-19 on US counties and their ability to respond.

Design: We identified key individual, household and community characteristics influencing COVID-19 risks of infection and survival, guided by international experiences and consideration of epidemiological parameters of importance. Using publicly available data, we developed an open-access online tool that allows county-specific querying and mapping of risk factors. As an illustrative example, we assess the pairwise intersections of age (individual level), poverty (household level) and prevalence of group homes (community-level) in US counties. …

Recognizing And Addressing Mathematics Anxiety In Female Students, Amanda Sost

West Chester University Master’s Theses

Mathematics anxiety is a prevalent concern in the world of education. As a female mathematician myself, my own personal experiences led me to research the reasons why mathematics anxiety affects more girls than boys. Specifically this paper explores the basics of anxiety including its definition and causes. This definition provides a meaning behind discussing the authoritarian model of education and the importance behind creating a free democratic society, not only in the classroom but in the world. Specifically, the authoritarian style of pedagogy has many affects on students who are learning mathematics, which will be explored as one of the …

Diagnostic Accuracy Of Chest Computed Tomography Scans For Suspected Patients With Covid-19: Receiver Operating Characteristic Curve Analysis, Lianpin Wu, Qike Jin, Jie Chen, Jiawei He, David Brett-Major, Jianghu James Dong

Journal Articles: Epidemiology

BACKGROUND: Computed tomography (CT) scans are increasingly available in clinical care globally. They enable a rapid and detailed assessment of tissue and organ involvement in disease processes that are relevant to diagnosis and management, particularly in the context of the COVID-19 pandemic.

OBJECTIVE: The aim of this paper is to identify differences in the CT scan findings of patients who were COVID-19 positive (confirmed via nucleic acid testing) to patients who were confirmed COVID-19 negative.

METHODS: A retrospective cohort study was proposed to compare patient clinical characteristics and CT scan findings in suspected COVID-19 cases. A multivariable logistic model with …

Colorectal Cancer Screening Uptake: Differences Between Rural And Urban Privately-Insured Population, Mesnad Alyabsi, Jane L. Meza, K. M. Monirul Islam, Amr Soliman, Shinobu Watanabe-Galloway

Journal Articles: Epidemiology

Earlier studies investigated rural-urban colorectal cancer (CRC) screening disparities among older adults or used surveys. The objective was to compare screening uptake between rural and urban individuals 50-64 years of age using private health insurance. Data were analyzed from 58,774 Blue Cross Blue Shield of Nebraska beneficiaries. Logistic regression was used to assess the association between rural-urban and CRC screening use. Results indicate that rural individuals were 56% more likely to use the Fecal Occult Blood Test (FOBT) compared with urban residents, but rural females were 68% less likely to use FOBT. Individuals with few Primary Care Physician (PCP) visits …

Healthcare Practitioners’ Views Of Social Media As An Educational Resource, Adam G. Pizzuti, Karan H. Patel, Erin K. Mccreary, Emily Heil, Christopher M. Bland, Eric Chinaeke, Bryan L. Love, P Brandon Bookstaver

Faculty Publications

Social media is increasingly utilized as a resource in healthcare. We sought to identify perceptions of using social media as an educational tool among healthcare practitioners. An electronic survey was distributed to healthcare administrators, nurses, nurse practitioners, pharmacists, physicians, and physician assistants f hospital systems and affiliated health science schools in Georgia, Maryland, South Carolina, and Wisconsin. Survey questions evaluated respondents' use and views of social media for educational purposes and workplace accessibility using a Likert scale (1 = strongly disagree, 5 = strongly agree). Nurses (75%), pharmacists (11%), and administrators (7%) were the most frequent respondents. Facebook® (27%), Pinterest® …

An Examination Of Factors That Impact The Choices Of Female Athletes In Pursuit Of A Career In Collegiate Sports Leadership, Gloria Lynn Bradley

Wayne State University Dissertations

Abstract

The Social Cognitive Career Theory was applied to examine how the desire to coach or administrate are impacted by self-efficacy, occupational valence, perceived hindrance, and role model influence. This study was conducted to address the underrepresentation of females in collegiate sports leadership positions. The study examined if being coached by males or if males in leadership positions is preferred. Women coach less than half, (40.2%) of women’s sports and women account for 19.6% percent of administrators in college athletic departments. Hypothetically, the results of this study will support and enhance the NCAA college sports model by revealing quantitative data …

Mapping Language Function With Task-Based Vs. Resting-State Functional Mri, Ki Yun Park, John J. Lee, Donna Dierker, Laura M. Marple, Carl D. Hacker, Jarod L. Roland, Daniel S. Marcus, Mikhail Milchenko, Michelle M. Miller-Thomas, Tammie L. Benzinger, Joshua S. Shimony, Abraham Z. Snyder, Eric C. Leuthardt

Open Access Publications

BACKGROUND: Use of functional MRI (fMRI) in pre-surgical planning is a non-invasive method for pre-operative functional mapping for patients with brain tumors, especially tumors located near eloquent cortex. Currently, this practice predominantly involves task-based fMRI (T-fMRI). Resting state fMRI (RS-fMRI) offers an alternative with several methodological advantages. Here, we compare group-level analyses of RS-fMRI vs. T-fMRI as methods for language localization.

PURPOSE: To contrast RS-fMRI vs. T-fMRI as techniques for localization of language function.

METHODS: We analyzed data obtained in 35 patients who had both T-fMRI and RS-fMRI scans during the course of pre-surgical evaluation. The RS-fMRI data were analyzed …

Spiritual Coping As A Mediator Of Distress And Posttraumatic Growth Among Adult Female Survivors Of Sexual Abuse By Religious Leaders, Angela R. St. Hillaire

Dissertations

Problem

Posttraumatic growth has been defined as the positive psychological and behavioral changes that come about in the aftermath of a struggle with traumatic life events. The literature notes the existence of posttraumatic growth among survivors of intimate partner violence, childhood and/or adult sexual abuse, bereavement, terrorism, and other events. This study explored posttraumatic growth in a sample of female survivors of sexual abuse by religious leaders by examining how distress, spiritual coping, and posttraumatic growth were related in this population. This study examined the mediatory role of spiritual coping between distress and posttraumatic growth.

Method

Surveys that measured spiritual …

The Impact Of A Wireless Audio System On Communication In Robotic-Assisted Laparoscopic Surgery: A Prospective Controlled Trial, Ziv Tsafrir, Kirsten Janosek-Albright, Joelle Aoun, Mireya Diaz-Insua, Abd-El-Rahman Abd-El-Barr, Lauren Schiff, Shobhana Talukdar, Mani Menon, Adnan R. Munkarah, Evan Theoharis, David Eisenstein

Obstetrics, Gynecology and Women's Health Services Articles

BACKGROUND: Robotic surgery presents a challenge to effective teamwork and communication in the operating theatre (OR). Our objective was to evaluate the effect of using a wireless audio headset device on communication, efficiency and patient outcome in robotic surgery.

METHODS AND FINDINGS: A prospective controlled trial of team members participating in gynecologic and urologic robotic procedures between January and March 2015. In the first phase, all surgeries were performed without headsets (control), followed by the intervention phase where all team members used the wireless headsets. Noise levels were measured during both phases. After each case, all team members evaluated the …

Paclitaxel-Coated Zilver Ptx Drug-Eluting Stent Treatment Does Not Result In Increased Long-Term All-Cause Mortality Compared To Uncoated Devices., Michael D Dake, Gary M Ansel, Marc Bosiers, Andrew Holden, Osamu Iida, Michael R Jaff, Aaron E Lottes, Erin E O'Leary, Alan T Saunders, Marc Schermerhorn, Hiroyoshi Yokoi, Thomas Zeller

Heart and Vascular Articles

PURPOSE: Patient-level data from two large studies of the Zilver PTX drug-eluting stent (DES) with long-term follow-up and concurrent non-drug comparator groups were analyzed to determine whether there was an increased mortality risk due to paclitaxel.

METHODS: Data from the Zilver PTX randomized controlled trial (RCT) and Zilver PTX and bare metal stent (BMS) Japan post-market surveillance studies were analyzed. Five-year follow-up is complete in both DES studies; follow-up for the BMS study was limited to 3 years and is complete. Kaplan-Meier analyses assessed mortality. A Cox proportional hazards model identified significant factors related to mortality.

RESULTS: In the RCT, …

Integrating A Multidisciplinary Pain Team And Chiropractic Care In A Community Health Center: An Observational Study Of Managing Chronic Spinal Pain, Christopher Prater, Melissa Tepe, Patrick Battaglia

Open Access Publications

BACKGROUND: Chronic spinal pain is one of the most common diseases in the United States. Underserved patients are most affected, and disproportionately may use opioid medications as they lack access to other therapies. It is therefore important to develop systems to treat spinal pain within the primary medical home.

METHODS: We designed a prospective observational pilot study at a community health center to measure the effectiveness of two interventions among an underserved population: a multidisciplinary pain team and chiropractic care. Study outcomes were pain and functional disability measured by the Pain Disability Questionnaire (PDQ), and reduction of opioid dose at …

The Effects Of Csr And Female Presence In Corporate Governance On Firm Tax Avoidance, Madeline Karlberg

Honors Theses and Capstones

No abstract provided.

Do Cognitive Distortions And Coping Skills Predict Scar Acceptance And Body Esteem In Women With Implantable Cardioverter Defibrillators Or Pacemakers?, Nora Brier

PCOM Psychology Dissertations

The purpose of this study was to examine whether cognitions and coping skills predict scar acceptance and body esteem in women 18 years and older with implantable cardioverter defibrillators (ICDs) or pacemakers. A convenience sample of 272 individuals responded to a Facebook post. The measures were a demographic questionnaire, the Social Problem Solving Inventory-Revised (Short) (SPSI-R:S), the Body Esteem Scale for Adolescents and Adults, the Patient Scar Assessment Questionnaire (PSAQ), the Florida Patient Acceptance Survey, and the Inventory of Cognitive Distortions (ICD). Pearson correlation coefficient results revealed a moderate negative correlation between Negative Problem Orientation (NPO) and Body Esteem (Weight), …

Should The Pbl Tutor Be Present? A Cross-Sectional Study Of Group Effectiveness In Synchronous And Asynchronous Settings, Samuel Edelbring, Siw Alehagen, Evalotte Mörelius, Annakarin Johansson, Patrik Rytterström

Research outputs 2014 to 2021

Background: The tutorial group and its dynamics are a cornerstone of problem-based learning (PBL). The tutor's support varies according to the setting, and it is pertinent to explore group effectiveness in relation to different settings, for example online or campus-based. The PBL groups' effectiveness can partly be assessed in terms of cognitive and motivational aspects, using a self-report tool to measure PBL group effectiveness, the Tutorial Group Effectiveness Instrument (TGEI). This study's aim was to explore tutor participation in variations of online and campus-based tutorial groups in relation to group effectiveness. A secondary aim was to validate a tool for …

Definitions, Sources And Self-Reported Consumption Of Regionally Grown Fruits And Vegetables In Two Regions Of Australia, Katherine Kent, Stephanie Godrich, Sandra Murray, Stuart Auckland, Lauren Blekkenhorst, Beth Penrose, Johnny Lo, Amanda Devine

Research outputs 2014 to 2021

Regional food systems are complex networks, with numerous retail sources that underpin a local economy. However, evidence is limited regarding how consumers define, identify, and source regionally grown fresh fruits and vegetables (RGFFV). A cross-sectional study was conducted in Tasmania (TAS) and South Western Australia (SWA) to compare how RGFFV are defined, identified and sourced by consumers, including self-reported consumption of selected RGFFV. Survey data were analyzed using the Chi-square test and t-tests. Results (TAS n = 120, SWA n = 123) identified that consumers had mixed perceptions of how RGFFV are defined, including produce sold at farmers markets, or …

The Relationship Between Chronic Health Conditions And Cognitive Deficits In Children, Adolescents, And Young Adults With Down Syndrome: A Systematic Review, Kellen C Gandy, Heidi A Castillo, Lara Ouellette, Jonathan Castillo, Philip J Lupo, Lisa M Jacola, Karen R Rabin, Kimberly P Raghubar, Maria M Gramatges

Library Staff Publications

BACKGROUND: Individuals with Down syndrome are predisposed to a number of chronic health conditions, but the relationship between these conditions and cognitive ability is not clear. The primary objective of this systematic review is to assess this relationship by evaluating studies that measure cognitive performance in the context of Down syndrome-associated chronic health conditions.

METHODS: A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Studies included in this review (1) included children, adolescent, and young adult participants with Down syndrome and one or more co-occurring health conditions; (2) were quantitative; …

2019-2020 Annual Report: Roger Williams University School Of Law, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.

Elecsys Csf Biomarker Immunoassays Demonstrate Concordance With Amyloid-Pet Imaging, James A. Doecke, Larry Ward, Samantha C. Burnham, Victor L. Villemagne, Qiao-Xin Li, Steven Collins, Christopher J. Fowler, Ekaterina Manuilova, Monika Widmann, Stephanie R. Rainey-Smith, Ralph N. Martins, Colin L. Masters, Aibl Research Group

Research outputs 2014 to 2021

Background: β-amyloid (Aβ) positron emission tomography (PET) imaging is currently the only Food and Drug Administration-approved method to support clinical diagnosis of Alzheimer's disease (AD). However, numerous research studies support the use of cerebrospinal fluid (CSF) biomarkers, as a cost-efficient, quick and equally valid method to define AD pathology. Methods: Using automated Elecsys® assays (Roche Diagnostics) for Aβ (1-42) (Aβ42), Aβ (1-40) (Aβ40), total tau (tTau) and phosphorylated tau (181P) (pTau), we examined CSF samples from 202 participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing cohort, to demonstrate the concordance with pathological AD via PET imaging. …

Anterior Cruciate Ligament Injuries In Australian Football: Should Women And Girls Be Playing? You're Asking The Wrong Question, Aaron Fox, Jason Bonacci, Samantha Hoffmann, Sophia Nimphius, Natalie Saunders

Research outputs 2014 to 2021

Anterior cruciate ligament (ACL) injuries have been a rising concern in the early years of the women's Australian Football League (AFLW), eliciting headlines of a â € knee crisis' surrounding the league. There has been a focus on female biology as the primary factor driving the high rate of ACL injuries in the AFLW. Emphasising Australian football (AF) as being dangerous predominantly due to female biology may be misrepresenting a root cause of the ACL injury problem, perpetuating gender stereotypes that can restrict physical development and participation of women and girls in the sport. We propose that an approach addressing …

First Age- And Gender-Matched Case-Control Study In Australia Examining The Possible Association Between Toxoplasma Gondii Infection And Type 2 Diabetes Mellitus: The Busselton Health Study, Aus Molan, Kazunori Nosaka, Michael Hunter, Jinxia Zhang, Xiaoni Meng, Manshu Song, Wei Wang

Research outputs 2014 to 2021

An emerging field of research is starting to examine the association of infectious pathogens with type 2 diabetes mellitus (T2DM). An understudied parasite of interest is Toxoplasma gondii. Globally, very few studies have been conducted to investigate this association. Additionally, very little data exists on the prevalence of T. gondii in the general Australian population. Our group sought to determine the prevalence, association, and risk factors between T. gondii infection and T2DM from a representative Australian human population. Through a cross-sectional, age-A nd gender-matched case-control study, 150 subjects with T2DM together with 150 control subjects from the Busselton Health Study …