Digital Commons Network^™

Influence Of Immunology Knowledge On Healthcare And Healthy Lifestyle, N.L. Abu Kassim, A. Saleh Huddin, J.I. Daoud, M.T. Rahman

Research Publications (2016 to 2020)

Completing a course in Immunology is expected to improve health care knowledge (HCK), which in turn is anticipated to influence a healthy lifestyle (HLS), controlled use of health care services (HCS) and an awareness of emerging health care concerns (HCC). This cross-sectional study was designed to determine whether these interrelationships are empirically supported. Participants involved in this study were government servants from two ministries in Malaysia (n = 356) and university students from a local university (n = 147). Participants were selected using the non-random purposive sampling method. Data were collected using a self-developed questionnaire, which had been validated in …

Familiality Of Mood Repair Responses Among Youth With And Without Histories Of Depression., Lauren M. Bylsma, Ilya Yaroslavsky, Johnathan Rottenberg, Enikő Kiss, Krisztina Kapornai, Kitti Halas, Roberta Dochnal, Eszter Lefkovics, Ildikό Baji, Ágnes Vetrό, Maria Kovacs

Psychology Faculty Publications

Affect regulation skills develop in the context of the family environment, wherein youths are influenced by their parents', and possibly their siblings', regulatory responses and styles. Regulatory responses to sadness (mood repair) that exacerbate or prolong dysphoria (maladaptive mood repair) may represent one way in which depression is transmitted within families. We examined self-reported adaptive and maladaptive mood repair responses across cognitive, social and behavioural domains in Hungarian 11- to 19-year-old youth and their parents. Offspring included 214 probands with a history of childhood-onset depressive disorder, 200 never depressed siblings and 161 control peers. Probands reported the most problematic mood …

Comorbid Substance Use Diagnoses And Partner Violence Among Offenders Receiving Pharmacotherapy For Opioid Dependence, Cory A. Crane, Robert C. Schlauch, Susan Devine, Caroline J. Easton

Psychology Faculty Publications

While previous studies find mixed evidence of an association between opioid use and intimate partner violence perpetration among community samples, initial evidence has detected increased rates of partner violence among individuals receiving pharmacological intervention for opioid dependence. The current study evaluated the role of current comorbid substance use diagnoses, a robust risk factor for violent behavior, on the likelihood of perpetrating partner violence among a high risk sample of offenders receiving pharmacological intervention for opioid dependence. The authors analyzed self-report data provided by 81 (55 male) opioid dependent offenders during a court-ordered substance use interview. Approximately one-third of the sample …

Volumetric Analysis Of The Lips In Aging African American And Caucasian Females, David William Bowen

All ETDs from UAB

The objective of this study was to perform a volumetric analysis of the lips at rest and upon smiling in African American and Caucasian females distributed throughout five age groups. Materials and Methods: Three-dimensional surface facial images of 100 African American females and 100 Caucasian females were obtained using the 3dMDTMface system (3dMDface, Atlanta GA). Images were analyzed using the Aging Evaluation Analysis (AEVA) software (Eotech, Paris, France) to assess lip volume at rest and upon smile. The following linear measurements were also calculated upon smiling and non-smiling: subnasale-stomion superius, commissure-commissure, stomion inferius-labiomental sulcus. Gingival display and crown length was …

Differences In Memory Functioning Between Children With Attention-Deficit/Hyperactivity Disorder And/Or Focal Epilepsy., Sylvia E Lee, Michelle Y Kibby, Morris J Cohen, Lisa Stanford, Yong Park, Suzanne Strickland

Publications

Prior research has shown that attention-deficit/hyperactivity disorder (ADHD) and epilepsy are frequently comorbid and that both disorders are associated with various attention and memory problems. Nonetheless, limited research has been conducted comparing the two disorders in one sample to determine unique versus shared deficits. Hence, we investigated differences in working memory (WM) and short-term and delayed recall between children with ADHD, focal epilepsy of mixed foci, comorbid ADHD/epilepsy and controls. Participants were compared on the Core subtests and the Picture Locations subtest of the Children's Memory Scale (CMS). Results indicated that children with ADHD displayed intact verbal WM and long-term …

Effect Of Anthelminthic Treatment On Helminth Infection And Related Anaemia Among School-Age Children In Northwestern Ethiopia, Yonas Yimam, Abraham Degarege, Berhanu Erko

Journal Articles: Epidemiology

BACKGROUND: Information about improvements in the health status of population at-risk of helminth infection after anthelminthic treatment helps to evaluate the effectiveness of the large scale deworming program. The objectives of this study were to assess the impact of anthelminthic treatment on the prevalence and intensity of intestinal helminth infection, haemoglobin level and prevalence of anaemia among school-age children.

METHODS: A total of 403 children attending Tikur Wuha Elementary School in Jiga, northwestern Ethiopia were enrolled in this study between February and March 2011. Formol-ether concentration and Kato-Katz methods were used to examine stool for intestinal helminth infections at baseline …

Behavioral And Psychological Aspects Of Exercise Across Stages Of Eating Disorder Recovery, Anna M. Bardone-Cone, M. K. Higgins, Sara M. St George, Ilyssa Rosenzweig, Lauren M. Schaefer, Ellen E. Fitzsimmons-Craft, Taylor M. Henning, Brittany F. Preston

Psychology Faculty Publications

This study examined the relationship between behavioral and psychological aspects of exercise and eating disorder recovery. Participants were categorized as having an eating disorder (n = 53), partially recovered (n = 15), fully recovered (n = 20), or non-eating disorder controls (n = 67). Groups did not differ significantly in time spent exercising, but did differ in exercise intensity, guilt-related exercise, obsessive exercise cognitions, and appearance/weight management and stress/mood management motivations for exercise. Results support the importance of measuring psychological aspects of exercise in particular across the course of an eating disorder.

Respiratory Sinus Arrhythmia Reactivity To A Sad Film Predicts Depression Symptom Improvement And Symptomatic Trajectory, Vanessa Panaite, Alexandra Cowden Hindash, Lauren M. Bylsma, Brent J. Small, Kristen Salomon, Johnathan Rottenberg

Psychology Faculty Publications

Respiratory sinus arrhythmia (RSA) reactivity, an index of cardiac vagal tone, has been linked to self-regulation and the severity and course of depression (Rottenberg, 2007). Although initial data supports the proposition that RSA withdrawal during a sad film is a specific predictor of depression course (Fraguas, 2007; Rottenberg, 2005), the robustness and specificity of this finding are unclear. To provide a stronger test, RSA reactivity to three emotion films (happy, sad, fear) and to a more robust stressor, a speech task, were examined in currently depressed individuals (n = 37), who were assessed for their degree of symptomatic improvement over …

Nonsuicidal Self-Injury As A Risk Factor For Purging Onset: Negatively Reinforced Behaviours That Reduce Emotional Distress, Elizabeth N. Riley, Heather A. Davis, Jessica L. Combs, Carol E. Jordan, Gregory T. Smith

Psychology Faculty Publications

Both nonsuicidal self-injury (NSSI) and purging behaviour are thought to involve harm to the self. The acquired capability for self-harm model holds that engaging in one self-harming behaviour increases the capability to tolerate harm to the self, thus increasing risk for engaging on other such behaviours. In addition, both behaviours are thought to serve the similar function of relief from distress. We thus tested whether engagement in one of these behaviours predicts the subsequent onset of the other. In a longitudinal design, 1158 first-year college women were assessed for purging and NSSI at two time points. Engagement in NSSI at …

Effect Of Vitamins C And E On Endothelial Function In Type 1 Diabetes Mellitus, Rachel-Marie Cazeau, Hong Huang, John A. Bauer, Robert P. Hoffman

Pediatrics Faculty Publications

Background/Objectives. Endothelial dysfunction due to hyperglycemia-induced oxidative damage is an important predictor of future cardiovascular risk in patients with type 1 diabetes mellitus (T1DM) and is present in adolescent T1DM. We hypothesized that combined treatment with the antioxidant vitamins C and E might improve endothelial function (EF) and other biochemical risk factors in adolescents with T1DM. Subjects/Methods. Open-label antioxidant supplementation was given for six weeks with endpoint measurements collected at baseline and study completion. Endpoints measured included EF and plasma measurements of biochemical endothelial risk. Results. Two males and 7 females were studied. Mean age was 12.9 ± 0.9 yrs; …

Women's Professional Sports: A Case Study On Practices That Could Increase Their Profitability, Danielle H. Mcardle

Honors Undergraduate Theses

Women’s professional sports leagues have often been considered a risky business endeavor. Critics cite low attendance, lack of sponsorships, lack of media rights deals, and numerous other reasons for why women’s professional sports leagues are not profitable. In analyzing the current landscape of women’s professional sport leagues, this paper uses a case study approach to develop a strategy that will highlight lessons learned from past women’s professional sports leagues, current professional sports leagues, sponsorship agreements, fans, social, digital, and mobile marketing strategies, and management practices to show how the business of women’s sports could be made into a more profitable …

"Don't Have Sex, You'll Get Pregnant And Die!": Female University Students' Experiences With Abstinence-Only Education, Jillian Grace Norwick

Theses and Dissertations--Family Sciences

Based on the various changes in sexual education, many schools throughout the United States still teach abstinence-only education. There is a plethora of literature on the effectiveness of sexual education programs as well as adolescent sexual practices. However, there is a deep gap in literature on students' perspectives of their sexual education and the possible effects it has on their experiences while in college. Therefore, this phenomenological study aims to explore and describe the essence of the experience female university students have regarding the abstinence-only education they received during secondary schooling. The informants (n=12) were 19-22 year old female university …

Voting, Politics, And Gender: Has America Paved The Way For A Female President?, Hannah Bower

CMC Senior Theses

The purpose of this study is to understand the impact of candidate gender on voting behavior in presidential elections in the United States. By delving into the vice presidential nominations of Geraldine Ferraro in 1984, and Sarah Palin in 2008, I provided the baseline for the experiences of Carly Fiorina and Hillary Clinton’s presidential campaigns in 2016. Ultimately, I present the argument that the United States is ready for a female president, either this year or in the near future.

Neighborhood-Level Poverty At Menarche And Prepregnancy Obesity In African-American Women, Andrea E. Cassidy-Bushrow, Rosalind M. Peters, Charlotte Burmeister, Lawrence F. Bielak, Dayna A. Johnson

Public Health Sciences Articles

Introduction: Menarche is a critical time point in a woman's reproductive system development; exposures at menarche may influence maternal health. Living in a poorer neighborhood is associated with adult obesity; however, little is known if neighborhood factors at menarche are associated with prepregnancy obesity.

Methods: We examined the association of neighborhood-level poverty at menarche with prepregnancy body mass index category in 144 pregnant African-American women. Address at menarche was geocoded to census tract (closest to year of menarche); neighborhood-level poverty was defined as the proportion of residents living under the federal poverty level. Cumulative logistic regression was used to examine …

Follicular Lymphoma Tregs Have A Distinct Transcription Profile Impacting Their Migration And Retention In The Malignant Lymph Node, Hristina Nedelkovska, Alexander F. Rosenberg, Shannon P. Hilchey, Ollivier Hyrien, W. Richard Burack, Sally A. Quataert, Christina M. Baker, Mitra Azadniv, Stephen L. Welle, Stephen M. Ansell, Minsoo Kim, Steven H. Bernstein

Biology

We have previously shown that regulatory T cells (Tregs) infiltrating follicular lymphoma lymph nodes are quantitatively and qualitatively different than those infiltrating normal and reactive nodes. To gain insight into how such Treg populations differ, we performed RNA sequence (RNAseq) analyses on flow sorted Tregs from all three sources. We identify several molecules that could contribute to the observed increased suppressive capacity of follicular lymphoma nodal tregs, including upregulation of CTLA-4, IL-10, and GITR, all confirmed by protein expression. In addition, we identify, and confirm functionally, a novel mechanism by which Tregs target to and accumulate within a human tumor …

Cogstate Computerized Memory Tests In Patients With Brain Metastases: Secondary Endpoint Results Of Nrg Oncology Rtog 0933., Chip Caine, Snehal Deshmukh, Vinai Gondi, Minesh Mehta, Wolfgang Tomé, Benjamin W. Corn, Andrew Kanner, Howard Rowley, Vijayananda Kundapur, Albert Denittis, Jeffrey Noah Greenspoon, Andre A. Konski, Glenn S. Bauman, Adam Raben, Wenyin Shi, Merideth Wendland, Lisa Kachnic

Department of Radiation Oncology Faculty Papers

Whole brain radiotherapy (WBRT) is associated with memory dysfunction. As part of NRG Oncology RTOG 0933, a phase II study of WBRT for brain metastases that conformally avoided the hippocampal stem cell compartment (HA-WBRT), memory was assessed pre- and post-HA-WBRT using both traditional and computerized memory tests. We examined whether the computerized tests yielded similar findings and might serve as possible alternatives for assessment of memory in multi-institution clinical trials. Adult patients with brain metastases received HA-WBRT to 30 Gy in ten fractions and completed Hopkins Verbal Learning Test-Revised (HVLT-R), CogState International Shopping List Test (ISLT) and One Card Learning …

Can Office Blood Pressure Readings Predict Masked Hypertension?, Mark M. Mitsnefes, Chris Pierce, Joseph Flynn, Joshua Samuels, Janis Dionne, Susan Furth, Bradley A. Warady, Ckid Study Group

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Studies in children with chronic kidney disease indicate a high prevalence of masked hypertension detected by ambulatory blood pressure monitoring (ABPM). However, it is not well known if the frequency of masked hypertension is related to the level of normal casual blood pressure (BP).

METHODS/RESULTS: We hypothesized that lower levels of normal casual BP are associated with a lower prevalence of masked hypertension. Data from the chronic kidney disease (CKiD) cohort were analyzed cross-sectionally across multiple visits. The majority of children with normal casual BP also had normal wake and sleep ABP (60 %), even at the highest percentiles …

Vector Competence Of American Mosquitoes For Three Strains Of Zika Virus, James Weger-Lucarelli, Claudia Rückert, Nunya Chotiwan, Chilinh Nguyen, Selene M. Garcia Luna, Joseph R. Fauver, Brian D. Foy, Rushika Perera, William C. Black, Rebekah C. Kading, Gregory D. Ebel

Journal Articles: Epidemiology

In 2015, Zika virus (ZIKV; Flaviviridae; Flavivirus) emerged in the Americas, causing millions of infections in dozens of countries. The rapid spread of the virus and the association with disease outcomes such as Guillain-Barré syndrome and microcephaly make understanding transmission dynamics essential. Currently, there are no reports of vector competence (VC) of American mosquitoes for ZIKV isolates from the Americas. Further, it is not clear whether ZIKV strains from other genetic lineages can be transmitted by American Aedes aegypti populations, and whether the scope of the current epidemic is in part facilitated by viral factors such as enhanced replicative fitness …

The Relationship Between “Feeling Fat” And Weight-Gain Feedback In A Non-Eating-Disordered Female Sample: Clinical Perfectionism As A Related Variable, Jenna Dilossi

PCOM Psychology Dissertations

This study investigated the relationship between feeling fat and weight-gain feedback in a sample of 111 non-eating-disordered women between the ages of 18 to 45 years. Specifically, this study examined feeling fat with regard to feedback type (i.e., weight reading or clothing size) and social context (i.e., alone or with peers present). Additionally, perfectionism was examined as a related variable within this relationship. Hypotheses related to social context and perfectionism were supported, whereas hypotheses related to feedback type were not supported. Results indicated a significant main effect for social context on feeling fat scores and an insignificant interaction effect for …

The Impact Of Internet Social Networking On Young Women’S Mood And Body Image Satisfaction: An Experimental Design, Tara Scirrotto Drames

PCOM Psychology Dissertations

In the present study, the impact of viewing various types of female images online was examined to approximate the potential impact of online photo viewing on social-networking sites. Two-hundred forty-one young women between the ages of 18 and 30 years were recruited on social-networking sites to participate. In this randomized-controlled, Internet-based study, participants were randomly assigned to one of the following groups of roughly 50 participants each: (a) very attractive-thin, (b) very attractive-not thin, (c) average-attractive-thin, (d) average attractive-not thin, and (c) control (landscapes). All participants viewed the corresponding images online via a “mock” social networking page created by the …

Bone Health Echo: Telementoring To Improve Osteoporosis Care, E Michael Lewiecki, Matthew F. Bouchonville, David H. Chafey, Arthur Bankhurst, Sanjeev Arora

Project ECHO Bibliography

Extension for Community Healthcare Outcomes creates knowledge networks that enable a transition from centralized specialty care at academic institutions to empowerment of primary care providers to provide more highly skilled care closer to home.

Evaluation Of Total Daily Dose And Glycemic Control For Patients Taking U-500 Regular Insulin Admitted To The Hospital, Andrew O/ Paulus, Jeffrey A. Colburn, Mark W. True, Darrick J. Beckman, Richard P. Davis, Jana L. Wardian Phd, Sky D. Graybill, Irene Folaron, Jack E. Lewi

Journal Articles: Hospital Medicine

OBJECTIVE: Patients using U-500 regular insulin are severely insulin resistant, requiring high doses of insulin. It has been observed that a patient's insulin requirements may dramatically decrease during hospitalization. This study sought to systematically investigate this phenomenon.

METHODS: We performed a retrospective chart review of patients with U-500 insulin outpatient regimens who were admitted to the San Antonio Military Medical Center over a 5-year period. Each patient's outpatient total daily dose (TDD) of insulin was compared to the average inpatient TDD. The outpatient estimated average glucose (eAG) was calculated from the glycated hemoglobin (HbA1c) and compared to the average inpatient …

Current Workforce Characteristics And Burnout In Pediatric Emergency Medicine., Marc H. Gorelick, Robert Schremmer, Holly Ruch-Ross, Carrie Radabaugh, Steven Selbst

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: Changes in health care delivery and graduate medical education have important consequences for the workforce in pediatric emergency medicine (PEM). This study compared career preparation and potential attrition of the PEM workforce with the prior assessment from 1998.

METHODS: An e-mail survey was sent to members of the American Academy of Pediatrics (AAP) Section on EM and to non-AAP members board certified in PEM. Information on demographics, practice characteristics and professional activities, career preparation, future plans, and burnout (using two validated screening questions) was analyzed using standard descriptive statistics.

RESULTS: Of 2,120 surveys mailed, 895 responses were received (40.8% …

Spermatogenesis Drives Rapid Gene Creation And Masculinization Of The X Chromosome In Stalk-Eyed Flies (Diopsidae), Richard H. Baker, Apurva Narechania, Rob Desalle, Philip M. Johns, Josephiine A. Reinhardt, Gerald S. Wilkinson

Biology

Throughout their evolutionary history, genomes acquire new genetic material that facilitates phenotypic innovation and diversification. Developmental processes associated with reproduction are particularly likely to involve novel genes. Abundant gene creation impacts the evolution of chromosomal gene content and general regulatory mechanisms such as dosage compensation. Numerous studies in model organisms have found complex and, at times contradictory, relationships among these genomic attributes highlighting the need to examine these patterns in other systems characterized by abundant sexual selection. Therefore, we examined the association among novel gene creation, tissue-specific gene expression, and chromosomal gene content within stalk-eyed flies. Flies in this family …

Singaporean Mothers' Perception Of Their Three-Year-Old Child's Weight Status: A Cross-Sectional Study, Tuck Seng Cheng, Et Al., Yee-Man Ivy Lau

Research Collection School of Social Sciences

Objective: Inaccurate parental perception of their child's weight status is commonly reported in Western countries. It is unclear whether similar misperception exists in Asian populations. This study aimed to evaluate the ability of Singaporean mothers to accurately describe their three-year-old child's weight status verbally and visually.

Identification And Use Of Frailty Indicators From Text To Examine Associations With Clinical Outcomes Among Patients With Heart Failure., Yijun Shao, April F Mohanty, Ali Ahmed, Charlene R Weir, Bruce E Bray, Rashmee U Shah, Douglas Redd, Qing Zeng-Treitler

Clinical Research and Leadership Faculty Publications

Frailty is an important health outcomes indicator and valuable for guiding healthcare decisions in older adults, but is rarely collected in a quantitative, systematic fashion in routine healthcare. Using a cohort of 12,000 Veterans with heart failure, we investigated the feasibility of topic modeling to identify frailty topics in clinical notes. Topics were generated through unsupervised learning and then manually reviewed by an expert. A total of 53 frailty topics were identified from 100,000 notes. We further examined associations of frailty with age-, sex-, and Charlson Comorbidity Index-adjusted 1-year hospitalizations and mortality (composite outcome) using logistic regression. Frailty (≤ 4 …

Contextualizing Multilayered Sexual Subjectivities Of Heterosexual Black Female Undergraduate Students At A Predominantly White Institution In The South, Amarachi Rossana Anakaraonye

Theses and Dissertations

This study uses an intersectional theoretical framework to examine Black college women’s sexual health by focusing on how they engage in sexual decision making within their social contexts. This qualitative study analyzed 20 individual in-depth interviews of Black female undergraduate students, ages 18-22, who attend a predominantly white institution (PWI) in the Southeastern United States. The themes that emerged from qualitative data analysis include Black female undergraduate students’ perceptions of the sexual culture of their campus and the protective strategies they employ to navigate the sexual culture in order to achieve and/or maintain physical, emotional, and social well-being. Key findings …

Nutritional Status And Tuberculosis Risk In Adult And Pediatric Household Contacts, Omowunmi Aibana, Xeno Acharya, Chuan-Chin Huang, Mercedes C Becerra, Jerome T Galea, Silvia S Chiang, Carmen Contreras, Roger Calderon, Rosa Yataco, Gustavo E Velásquez, Karen Tintaya, Judith Jimenez, Leonid Lecca, Megan B Murray

Faculty, Staff and Student Publications

BACKGROUND: Studies show obesity decreases risk of tuberculosis (TB) disease. There is limited evidence on whether high body mass index also protects against TB infection; how very high body mass indices influence TB risk; or whether nutritional status predicts this risk in children. We assessed the impact of body mass index on incident TB infection and disease among adults and children.

METHODS AND FINDINGS: We conducted a prospective cohort study among household contacts of pulmonary TB cases in Lima, Peru. We determined body mass index at baseline and followed participants for one year for TB infection and disease. We used …

Early Adverse Experiences And Health: The Transition To College, Kelly B. Filipkowski, Kristin E. Heron, Joshua M. Smyth

Psychology Faculty Publications

Objective: This study cross-sectionally and prospectively examined the impact of adversity experienced prior to college on the health and well-being of students adjusting to their first college semester. Methods: Two-hundred sixteen (216) first-year students completed measures of adverse life experiences, perceived stress, physical symptoms, and health-related behaviors during the first 2 weeks of college entry and again at the end of the first semester. Results: Reported adversity prior to college predicted greater perceived stress and physical symptoms at college entry and an increase in physical symptoms over the semester; perceived stress mediated the prospective changes. Early adversity …

Effective Combat Leadership: How Do Individual, Social, And Organizational Factors In The U.S. Army Reserve Cultivate Effective Women's Leadership In Dangerous Contexts?, Diana Drita Ellerman

Antioch University Dissertations & Theses

This research centered on the experiences of a dozen women who served in U.S. Army Reserve leadership positions. Although they served in dangerous contexts the Army had an exclusionary policy at the time that formally excluded the women from direct combat. The impetus for the research was Secretary of Defense Leon Panetta's announcement in January 2013 that the U.S. military would be eliminating the exclusionary policy. The purpose of this study was to gain insight into what individual, social, and organizational factors support women's effective leadership in dangerous contexts. The research utilized narrative inquiry in order to bring forth the …