Digital Commons Network^™

Structure-Activity Relationships For Dna Damage By Alkenylbenzenes In Turkey Egg Fetal Liver, Tetyana Kobets, Jian-Dong Duan, Klaus D. Brunnemann, Sylvain Etter, Benjamin Smith, Gary M. Williams

NYMC Faculty Publications

Certain alkenylbenzenes (AB), flavoring chemicals naturally occurring in spices and herbs, are established to be cytotoxic and hepatocarcinogenic in rodents. The purpose of the present study was to determine the DNA damaging potential of key representatives of this class using the Turkey Egg Genotoxicity Assay. Medium white turkey eggs with 22- to 24-day-old fetuses received three injections of nine AB with different carcinogenic potentials: safrole (1, 2 mg/egg), methyl eugenol (2, 4 mg/egg), estragole (20, 40 mg/egg), myristicin (25, 50 mg/egg), elemicin (20, 50 mg/egg), anethole (5, 10 mg/egg), methyl isoeugenol (40, 80 mg/egg), eugenol (1, 2.5 mg/egg), and isoeugenol …

Noteworthy News - Spring 2016, Conservatory Of Music

Noteworthy News

No abstract provided.

Faculty Preparedness For Developing, Evaluating And Revising Bsn Curriculum, Meredith L. Roberts

Nursing Education Research Conference (NERC)

Session presented on Saturday, April 9, 2016, and Friday, April 8, 2016:

Nurse educators are barraged with competencies, standards, outcomes, and initiatives to consider when developing, evaluating, or revising curriculum. Expert clinicians enter educator roles with minimal understanding of the expected skill set (Fitzpatrick, 2014). Research using constructivist grounded theory study discovered and compared the perceptions and processes of faculty related to their preparedness and confidence in evaluating, developing, and revising nursing curriculum. Fifteen faculty members from four colleges were interviewed. Faculty's constructions were used to develop a middle range descriptive theory Challenged and Overwhelmed. From further faculty recommendations on …

Central Role Of Glutamate Metabolism In The Maintenance Of Nitrogen Homeostasis In Normal And Hyperammonemic Brain, Arthur J. Cooper, Thomas M. Jeitner

NYMC Faculty Publications

Glutamate is present in the brain at an average concentration-typically 10-12 mM-far in excess of those of other amino acids. In glutamate-containing vesicles in the brain, the concentration of glutamate may even exceed 100 mM. Yet because glutamate is a major excitatory neurotransmitter, the concentration of this amino acid in the cerebral extracellular fluid must be kept low-typically µM. The remarkable gradient of glutamate in the different cerebral compartments: vesicles > cytosol/mitochondria > extracellular fluid attests to the extraordinary effectiveness of glutamate transporters and the strict control of enzymes of glutamate catabolism and synthesis in well-defined cellular and subcellular compartments in the …

Environmental Health News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Dr. Asli Aslan Faculty Feature

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Dr. Asli Aslan Faculty Feature

It Takes A Village And A Plan: Leadership Development Of Novice Faculty Through A Team Project, Alison H. Edie

Biennial Convention (CONV)

Session presented on Tuesday, November 10, 2015:

The purpose of this presentation is to demonstrate the use of a team project in the leadership development of novice nursing faculty. The successful transition of expert nurse clinicians into nurse faculty leaders requires an intentional, structured individualized leadership development plan, the support of the academic community and the relationship of an experienced nurse leader that serves as a mentor. The Sigma Theta Tau Nurse Faculty Leadership Academy (NFLA) program uses a team leadership project and mentoring to advance nursing education through the leadership development of novice nurse faculty. (Sigma Theta Tau International, …

Research Express News, Georgia Southern University

Research Express News

• In its third year, Georgia Southern’s Master of Healthcare Administration (MHA) program and the Jiann-Ping Hsu College of Public Health will sponsor the 2016 Healthcare Symposium. “Truths and Myths behind Childhood Vaccinations,” on March 24, 10 a.m. – 11:30 p.m., in the University’s Performing Arts Center (PAC). The symposium is free and open to students, staff, faculty and the community.

Research Express News, Georgia Southern University

Research & Economic Development

• In its third year, Georgia Southern’s Master of Healthcare Administration (MHA) program and the Jiann-Ping Hsu College of Public Health will sponsor the 2016 Healthcare Symposium. “Truths and Myths behind Childhood Vaccinations,” on March 24, 10 a.m. – 11:30 p.m., in the University’s Performing Arts Center (PAC). The symposium is free and open to students, staff, faculty and the community.

20-Hete Activates The Transcription Of Angiotensin-Converting Enzyme Via Nuclear Factor-Κb Translocation And Promoter Binding, Victor Garcia, Brian Shkolnik, Laura Milhau, John R. Falck, Michal Laniado Schwartzman

NYMC Faculty Publications

Increased vascular 20-hydroxyeicosatetraenoic acid (20-HETE), a cytochrome P450 arachidonic acid metabolite, promotes vascular dysfunction, injury, and hypertension that is dependent, in part, on the renin angiotensin system (RAS). We have shown that, in human microvascular endothelial cells, 20-HETE increases angiotensin-converting enzyme (ACE) mRNA, protein, and ACE activity via an epidermal growth factor receptor (EGFR)/tyrosine kinase/mitogen-activated protein kinase (MAPK)/inhibitor of κB kinase (IKK)β-mediated signaling pathway. In this work, we show that, similar to epidermal growth factor (EGF), 20-HETE (10 nM) activates EGFR by stimulating tyrosine phosphorylation; however, unlike 20-HETE, EGF does not induce ACE expression, and pretreatment with a neutralizing antibody …

Rising Tide 2016, Une Office Of Research And Scholarship, Edward Bilsky, Dani Deason, Josh Pahigian, Jennie E. Aranovitch, Laura M. Duffy, Shelly Tallack Caporossi, Marine Miller

Rising Tide

Research and scholarship highlights from University of New England community members. This issue highlights student and faculty research and projects within UNE's College of Arts and Sciences, College of Dental Medicine, College of Osteopathic Medicine, College of Pharmacy, Westbrook College of Health Professions, and projects and research from UNE's Centers for Excellence.

Impact Of Out-Of-Pocket Expenditure On Physical Therapy Utilization For Nonspecific Low Back Pain: Secondary Analysis Of The Medical Expenditure Panel Survey Data, Janet Dolot, Deborah Viola, Qiuhu Shi, Matthew Hyland

NYMC Faculty Publications

BACKGROUND: Physical therapy decreases low back pain, improves function, and may lead to decreased use of medical services. However, factors predicting physical therapy utilization for patients with low back pain are not well understood. OBJECTIVES: The purpose of this study was to identify the impact of out-of-pocket expenditure on physical therapy utilization for US adults with nonspecific low back pain. DESIGN: This study was a secondary analysis of retrospective Medical Expenditure Panel Survey data. METHODS: The participants were US adults with nonspecific low back pain. The outcome variable was the number of visits per episode of care. The research variable …

Women’S Education And World Peace: A Feminist Dream Comes True, Vijayan K. Pillai, Ya-Chien Wang

Social Work Faculty Publications & Presentations-Archive

No abstract provided.

W. Michael Weis, W. Michael Weis, Meg Miner

All oral histories

Weis recalls Myers wanting IWU's niche to be the multi-talented and sold everyone on the idea that IWU was already great and would be better. Prior to Myers there was a "micro university" focus and he supported that. Provost McNew was focused on establishing a liberal arts ideal; Myers didn't oppose that idea but also wanted to keep Nursing. He wanted to expand and grow the University and the faculty supported him. Myers inculcated a love of collecting among people and speculates that collecting helps you think about all the things surrounding the object--time period, materials--that it helps "broaden perspective …

Vadim Mazo, Vadim Mazo, Meg Miner

All oral histories

Mazo recalls his first conversation with Myers and the support he felt from him right away for their mutual interests in music and also discusses encounters he had with Myers in his studio and about "Musical Bridges," a program he feels Myers' interest in his work inspired. Mazo feels Myers was a personal inspiration with his example of curiosity. He credits the widening of his interest in bows and batons to Myers' influence. In turn, he is sharing his interests with his students. He speculates that visitors Myers brought in were to improve the intellectual health of the campus and …

Hypoacetylation, Hypomethylation, And Dephosphorylation Of H2b Histones And Excessive Histone Deacetylase Activity In Du-145 Prostate Cancer Cells, Shundong Cang, Xiaobin Xu, Yuehua Ma, Delong Liu, J W. Chiao

NYMC Faculty Publications

BACKGROUND: Hypoacetylation on histone H3 of human prostate cancer cells has been described. Little is known about the modifications of other histones from prostate cancer cells. METHODS: Histones were isolated from the prostate cancer cell line DU-145 and the non-malignant prostatic cell line RC170N/h. Post-translational modifications of histone H2B were determined by liquid chromatography-mass spectrometry (LC-MS)/MS. RESULTS: The histone H2B of the prostate cancer cell line DU-145 was found to have hypoacetylation, hypomethylation, and dephosphorylation as compared to the non-malignant prostatic cell line RC170N/h. H2B regained acetylation on multiple lysine residues, phosphorylation on Thr19, and methylation on Lys23 and Lys43 …

A Report On The Status Of Standards For Tenure And Promotion In Debate, Robin Rowland, Jarrod Atchison, Derek Buescher, Matthew Gerber, Steve Hunt, Ryan Galloway, Kelly Mcdonald, Jeff Jarman, Kelly Young, Tom Hollihan, David Zarefsky

Speaker & Gavel

In what follows, we first provide an overview of debate in order to explain the importance of the activity and then review the status of tenure and evaluation standards among directors/coaches in various types of programs across the country. A mass email was used to ask directors/coaches to submit information about the nature of their current appointment (tenure track, term appointment, and so forth) and the standards through which their performance is evaluated. In addition to seeking information about appointment and evaluation standards for current coaches, we reviewed material from previous developmental conferences and the Quail Roost document, as well …

Lindenwood University Faculty Meeting Minutes, 2016-2017, Lindenwood University

Faculty Meeting/Council Minutes

Lindenwood University Faculty Meeting Minutes, 2016-2017.

Misericordia University Faculty Research And Scholarly Work, Misericordia University

University Authors 2015-2016

No abstract provided.

Preparing For Domestic Violence And Associated Trauma: Are We Ready?, Melissa Rodas

Undergraduate Research Projects

Domestic violence is an important problem to consider amongst societal issues today. Statistics have consistently shown high rates of violence across the country, and many cases go unreported. Even if survivors are able to escape their situations, trauma often casts a long shadow after the abuse is gone. A best practice model that has been utilized in Tennessee is that of Family Justice Centers. These centers utilize a co-located model to give survivors multiple services in a centralized location. As these organizations find their beginnings, attention is being noted to how social work students are being prepared for such settings. …

Translational Significance Of Heme Oxygenase In Obesity And Metabolic Syndrome, Nader G. Abraham, Joshua M. Junge, George S. Drummond

NYMC Faculty Publications

The global epidemic of obesity continues unabated with sequelae of diabetes and metabolic syndrome. This review reflects the dramatic increase in research on the role of increased expression of heme oxygenase (HO)-1/HO-2, biliverdin reductase, and HO activity on vascular disease. The HO system engages with other systems to mitigate the deleterious effects of oxidative stress in obesity and cardiovascular disease (CVD). Recent reports indicate that HO-1/HO-2 protein expression and HO activity have several important roles in hemostasis and reactive oxygen species (ROS)-dependent perturbations associated with metabolic syndrome. HO-1 protects tissue during inflammatory stress in obesity through the degradation of pro-oxidant …

2016 Ruby Yearbook, Briana Keane, Rebecca L. Brown, Phoebe French, Romina Kalmeijer, Faraha Rathod, Taylor Manferdini, Ursinus College Senior Class

The Ruby Yearbooks, 1897-2020

A digitized copy of the 2016 Ruby, the Ursinus College yearbook.

Beta-Adrenergic Receptor Blockers In Hypertension: Alive And Well, William H. Frishman

NYMC Faculty Publications

Beta-adrenergic receptor blockers (β-blockers) are an appropriate treatment for patients having systemic hypertension (HTN) who have concomitant ischemic heart disease (IHD), heart failure, obstructive cardiomyopathy, aortic dissection or certain cardiac arrhythmias. β-Blockers can be used in combination with other antiHTN drugs to achieve maximal blood pressure control. Labetalol can be used in HTN emergencies and urgencies. β-Blockers may be useful in HTN patients having a hyperkinetic circulation (palpitations, tachycardia, HTN, and anxiety), migraine headache, and essential tremor. β-Blockers are highly heterogeneous with respect to various pharmacologic properties: degree of intrinsic sympathomimetic activity, membrane stabilizing activity, β selectivity, α-adrenergic blocking effects, …

Modification Of Expanded Nk Cells With Chimeric Antigen Receptor Mrna For Adoptive Cellular Therapy, Yaya Chu, Allyson Flower, Mitchell S. Cairo

NYMC Faculty Publications

NK cells are bone marrow-derived cytotoxic lymphocytes that play a major role in the rejection of tumors and cells infected by viruses. The regulation of NK activation vs inhibition is regulated by the expression of a variety of NK receptors (NKRs) and specific NKRs' ligands expressed on their targets. However, factors limiting NK therapy include small numbers of active NK cells in unexpanded peripheral blood and lack of specific tumor targeting. Chimeric antigen receptors (CAR) usually include a single-chain Fv variable fragment from a monoclonal antibody, a transmembrane hinge region, and a signaling domain such as CD28, CD3-zeta, 4-1BB (CD137), …

Research Brief Fiscal Year 2016, Nova Southeastern University

Research Briefs

No abstract provided.

Nsu Translational Research And Economic Development Fy 2016 Annual Report, Nova Southeastern University

Annual Reports

No abstract provided.

2016 Award Recipients, St. Norbert College

Norbertine Awards

A list of the Norbertine Leadership & Service Award recipients in 2016.

Ω-Amidase: An Underappreciated, But Important Enzyme In L-Glutamine And L-Asparagine Metabolism; Relevance To Sulfur And Nitrogen Metabolism, Tumor Biology And Hyperammonemic Diseases, Arthur J. Cooper, Yevgeniya I. Shurubor, Thambi Dorai, John T. Pinto, Elena P. Isakova, Yulia I. Deryabina, Travis T. Denton, Boris F. Krasnikov

NYMC Faculty Publications

In mammals, two major routes exist for the metabolic conversion of L-glutamine to α-ketoglutarate. The most widely studied pathway involves the hydrolysis of L-glutamine to L-glutamate catalyzed by glutaminases, followed by the conversion of L-glutamate to α-ketoglutarate by the action of an L-glutamate-linked aminotransferase or via the glutamate dehydrogenase reaction. However, another major pathway exists in mammals for the conversion of L-glutamine to α-ketoglutarate (the glutaminase II pathway) in which L-glutamine is first transaminated to α-ketoglutaramate (KGM) followed by hydrolysis of KGM to α-ketoglutarate and ammonia catalyzed by an amidase known as ω-amidase. In mammals, the glutaminase II pathway is …

2016 Nsu Fact Book, Nova Southeastern University

NSU Fact Book

This 24th edition of the Nova Southeastern University Fact Book reflects an expanding body of data and information that provides perspective on the university’s character, growth, and accomplishments.

The 2016 Fact Book includes narrative, numeric, and graphic representation of the university, including history, characteristics, and development of the institution. Data are presented in both tabular and graphic formats to provide pertinent detail, and general trends are highlighted.

Ilium 2016, Taylor University

Yearbooks (1898-Present)

The 2016 yearbook of Taylor University in Upland, Indiana.