Digital Commons Network^™

Synthetic Neuroactive Steroids Targeting Gaba-A Receptors As A Potential Therapy For Contraceptive-Associated Mood Disorders, Alexandria A. Davis

Scripps Senior Theses

4-10% of women who use hormonal oral contraceptives (HOCs) discontinue use after experiencing symptoms of anxiety, irritability, and depression in the first 3 months of administration. Previous studies have acknowledged a relationship between HOCs and emotional dysregulation but have not identified mechanisms by which HOCs have this effect. As a result, effective treatment options for HOC-induced mood disorders are lacking. Current theories implicate combined-HOCs, particularly those containing ethinyl estradiol and levonorgestrel (EE-LNG), in reducing neuroactive steroid levels. Specifically, HOC users show decreases in allopregnanolone, a positive allosteric modulator associated with neuronal inhibition and emotional regulation. The objective of this study …

Evaluating The Pathogenesis And Treatment Algorithms For Patients With Irritable Bowel Syndrome, Nimra Nasir

Capstone Showcase

Irritable Bowel Syndrome is a common gastrointestinal condition that is characterized by abdominal pain and discomfort and altered bowel habits. Irritable Bowel Syndrome is thought out to be a multifactorial disorder that involves GI dysmotility, symptomology, altered gut microbial environment and alteration of the CNS with mental health manifestations including depression and anxiety. Many theories of the pathophysiology of IBS have been put forward, however the exact etiology remains unclear to this day. IBS is diagnosed based on the Rome IV Criteria that represent one of the four subtypes; 1) IBS with constipation (IBS-C), 2) IBS with diarrhea (IBS-D) 3) …

Increasing Help-Seeking Among People With Depression: An Empirical Assessment Of A Static And Trending Norms Approach, Christopher Falco

CGU Theses & Dissertations

The current research examined whether making static and trending norms salient through persuasive messaging could increase help-seeking inclinations (i.e., attitudes, expectations, and intentions) among people with depression. Study 1 indicated that people with depressive symptomatology significantly underestimated the number of people who seek help for depression. Although approximately 66% of U.S. adults with depression met with professionals for help in 2020, on average, participants believed this rate was 35%. Most associations between norm perceptions and help-seeking inclinations were nonsignificant (e.g., perceived static norms were not significantly associated with help-seeking attitudes or outcome expectations; trending norm perceptions did not significantly relate …

Integrating Behavioral Health Into Family Medicine: Improving Access To Specialty Care Using A Collaborative Care Model, Christina Stephens

DNP Scholarly Projects

Primary care, an extensive of family medicine remains a key access point for patients entering the healthcare system. Accessing medical care and specialty psychiatric services is limited in rural communities. Patients often find exhaustive wait times, untimely referrals, and reliance on emergency services for crisis management. The primary care provider is able to help their community improve access to behavioral health care by using a collaborative approach. This quality improvement initiative used the framework produced by the AIMS Center at the University of Washington and adopted for use creating an 8-week intensive program in a family medical practice located in …

Integrating Behavioral Health Into Family Medicine: Improving Access To Specialty Care For Medically Underserved Community Using A Collaborative Care Model, Christina M. Stephens

DNP Scholarly Projects

Primary care, an extension of family medicine remains a key access point for patients entering the healthcare system. Accessing specialty psychiatric services can be limited in rural communities due to provider shortages and geographical constraints. Primary care providers can facilitate improved access to behavioral health services by introducing a collaborative approach to the traditional medical model. This quality improvement initiative adopted the collaborative care model originally produced by the University of Washington to treat common mental health conditions in the medical setting (2023). A team consisting of a primary care provider, behavioral health case manager and psychiatric consultant served nine …

Depression, Anxiety, And Stress Among Urban And Rural Adolescents In Shivamogga, Karnataka, Ajay Mallya, Raghavendraswamy Koppad, Praveen Kumar

Open Access archive

Background: Currently there are 1.3 billion adolescents worldwide, which makes up 16% of the world population. Over 20% of adolescents around the world are thought to have behavioural or mental health issues. Addressing mental health issues is very important for the promotion of positive health in adolescents. This study aimed to estimate the prevalence of depression, anxiety and stress among adolescents in urban and rural areas of Shivamogga. Methods: A cross-sectional study was conducted among 350 adolescents aged 16 to 19 years each from urban and rural areas of Shivamogga. Results: Depression, anxiety and stress were found to be 23.1%, …

Predictors Of Occupational Distress Of Catholic Priests On The Eastern Seaboard Of The United States, Michael D. Kostick, Xihe Zhu, Justin A. Haegele, Pete Baker

Human Movement Studies & Special Education Faculty Publications

With ever-increasing demands placed upon active priests in the United States, insight into protecting their mental health may help strengthen vocational resilience for individual priests. The purpose of this study was to examine the association of individual variables, workplace characteristics, and physical activity participation with occupational distress levels among Catholic priests. A 22-question survey consisting of a demographic questionnaire, the Clergy Occupational Distress Index, and the International Physical Activity Questionnaire was employed to collect individual variables, workplace characteristics, physical activity participation, and occupational distress levels of Catholic priests from the Eastern seaboard of the United States. Regression analyses showed that …

Relationship Between Spiritual Struggles And Health Outcomes In Adult Chronic Pain Patient Populations, Brianna Marie Todd

All-Inclusive List of Electronic Theses and Dissertations

Chronic pain affects about one-fifth of the worlds population. Although a biopsychosocial model is often applied, religious and spiritual factors are frequently neglected in the conceptualization of pain and its impact. Prior research has identified how religious and spiritual (R/S) struggles are associated with depression, pain catastrophizing, and pain disability in pain patients. However, few investigations have assessed how struggles affect the relationship between pain and well-being. The present study explored how R/S struggles affect the relationship between pain and well-being when tested as mediators and moderators, while accounting for the effects of age, gender, race, income, education, and religious …

The Relationship Between Attention-Deficit/Hyperactivity Disorder And Sluggish Cognitive Tempo, Anna Podrasky

PCOM Psychology Dissertations

Sluggish cognitive tempo (SCT) was first described as a syndrome associated with attention-deficit/hyperactivity disorder (ADHD); however, SCT may be a unique construct, independent of the presence of ADHD. Archival data from a specialty outpatient adult ADHD clinic were analyzed to further evaluate the relationship between SCT and ADHD. It was hypothesized that there would not be significant differences between ADHD and SCT on measures of anxiety, depression, neuroticism, and sleep disturbance. Second, it was hypothesized that after controlling for anxiety, depression, neuroticism, and sleep disturbance at level 1 of a hierarchical regression analysis, there would be no additive predictive relationship …

Introducing Mental Health Resources To Nurse Practitioner Residents, Tiffanie Bailey

Doctor of Nursing Practice Projects

This DNP Project identified the increased need for mental health resources after the COVID-19 pandemic. Studies showed the rate of anxiety, depression, and substance use has also been on the rise since the beginning of the pandemic. As the impact of the COVID-19 pandemic began to devastate the country mentally and physically, it became quickly apparent that additional resources to provide support for those suffering from mental illness were essential. This project aimed to introduce a Mental Health First Aid course within the Residency Program at the Center for Family Guidance. Participants were asked to complete a pre-test indicating their …

Increased Concern Of Suicide Behaviors In The Adolescent Population, Jaime Shareen-Porter Earle

Doctor of Nursing Practice Projects

This quality improvement project focused on addressing the concern for the increase of depression, anxiety, and self-harm behaviors among adolescents, which can lead to suicidal ideation and attempts. Suicide behaviors have increased among adolescents, and research revealed that suicide is the second leading cause of death in this population. An educational PowerPoint was presented to members of the community on suicide behaviors, how to identify the behaviors, and where to get support and resources in the community. Pre- and post-surveys were used to assess the participants' knowledge and confidence levels before and after project implementation. The surveys contained the same …

Community Educational Session On Identifying The Signs Of Depression And Resources Available, Desiree Young

Doctor of Nursing Practice Projects

The DNP Project was designed to educate the community on identifying the signs of depression and the community resources available to them. The intent of the project was to improve the community’s knowledge of depression symptoms and the community resources available that offer assistance to those dealing with these symptoms. There is a great need for education on depression signs, as many in various communities suffer from untreated depression, which often leads to negative outcomes. The impact of the project implementation was measured by using pre- and post-survey data evaluating the participants' overall knowledge of the signs of depression, stigma …

Anxiety And Depression In Older Adults Post Deepwater Horizon Oil Spill, Mickaela R. Reed

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research has investigated challenges that are created when one experiences a disaster within populations such as older adults and other vulnerable groups of people. However, there is little to no consideration given to how age in combination with trauma history are related to well-being after a disaster. Using two theories, socioemotional selectivity theory (SST, Carstensen, 2006) and the strength and vulnerability integration model (SAVI, Charles, 2010). I compared older adults post disaster vulnerabilty to depression and anxiety to that of younger adults with trauma history as a moderator. The 2,508 participants in the current study were from the Survey of …

Childhood Trauma, Stress, Gender, And Depression's Impact On Suicidal Behavior, Emily H. Mezni

Honors Undergraduate Theses

Suicide is one of the leading causes of death in young adults. Continuous prevention and intervention efforts throughout the world have been made to reduce suicide risk in this population. Two of the biggest known risk factors for suicide is childhood trauma, a traumatic event or events that occur during youth, and depression. Researching the impact childhood trauma and depression make in conjunction with other factors will help to increase knowledge of suicidal behavior. In this study, recent stress and gender will be factored with childhood trauma and depression severity to predict suicidal ideation and attempt. Recent stress is useful …

Student-Athlete Mental Health: University Of Montana Case Study, Abigail M. Sherwood

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Research suggests that Division I college-student athletes experience higher levels of stress and other behavioral health issues than their non-athlete counterparts, with up to 20% of them suffering from depression (Sudano et al., 2017). Two studies on student athletes’ well-being conducted in 2020, reported that athletes continue to report higher levels of mental health concerns (Johnson, 2022). Since the fall of 2020, rates of mental exhaustion, depression, and anxiety have improved minimally with rates remaining 1.5 to two times higher than reported before the COVID-19 pandemic (Johnson, 2022). Naomi Osaka withdrawing from the French Open in 2021 and Simone Biles …

Mental Health Impacts Of Covid-19 On U.S. Young Adults: A Thematic Analysis Of Depression, Anxiety, And Ptsd Experiences, Carol Meza, Viridiana Ortiz, Pedro Hernandez

School of Social Work Faculty Publications

This study explores the yet-to-be-fully-realized effects of the COVID-19 pandemic on mental health, particularly focusing on young adults between the ages of 18-39 years of age living in the United States during the COVID-19 pandemic. Employing a thematic content analysis, the study seeks to deepen our understanding of the impact of this novel virus on mental well-being, filling a gap in limited existing research. The theoretical framework in this study is the Disaster Response Cycle or the Disaster Response and Recovery Cycle, and it outlines the different phases that individuals and communities may experience during and after a disaster. The …

Development Of A Novel Measure To Assess For Alcohol Misuse In Older Adults: The Alcohol Misuse Scale For Older Adults (Amsoa), Nathan Jensen

College of Graduate Studies: Theses & Dissertations

Alcohol is the most regularly used intoxicating substance in most geographic locations. Alcohol use in the United States specifically is well over global averages. While alcohol misuse is generally considered to be understood as a problem for younger adults, it is often unrecognized and understudied older adult populations. Currently, there is an absence of a comprehensive tool measuring for developmentally salient behaviors, symptoms, and features of alcohol misuse in older adulthood, which blocks researchers’ ability to measure alcohol misuse well. The purpose of this study is to develop a psychometrically valid and reliable assessment of alcohol misuse for older adult …

Depression In African American Males And The Mental Health Stigma, Deanna Carrington

Dissertations and Theses

Depression is a common mental health disorder in the United States. In particular, African Americans have a greater risk of depression because they are predisposed to depressive symptoms as opposed to their White counterparts (Miller and Taylor, 2011). Moreover, African Americans are 20% more likely to experience psychological distress that leads to depression compared to other racial groups. While African American cultural norms focus on resilience and independence, discussion around mental health is discouraged, which leads to underreporting and delayed treatment. For males in the African American community, they can be hesitant to seek help, let alone discuss their experiences …

The Mental Health Of Southeast Asian American Lgbtqia+ Adults, Phetsamone P. Phoummavong

Dissertations and Theses

The current study examines the prevalence of and relationship between mental health outcomes (depressive symptoms, anxiety) and adverse childhood experiences (ACEs) among a sample of Southeast Asian Americans (age: M = 26.6, SD = 4.0) who self-identified as sexual and gender minorities (e.g., gay, lesbian, bisexual, nonbinary, transgender, queer/questioning, intersex, asexual and plus [LGBTQIA+]) (n = 41). Our national online survey was co-developed with a partnering community-based organization (CBO), Mekong NYC, and was disseminated through Southeast Asian American and/or LGBTQIA+ serving CBOs, university-affiliated organizations, and relevant affinity groups.

Results indicate that participants in our sample who identified as female, …

Belonging In The Psychic Nowhere: Racial Trauma, Racial Melancholia And Related Mental Health Outcomes Amongst South Asian Immigrants In The Us, Anusha M. Kumar

Dissertations and Theses

South Asian immigrants have experienced a nuanced immigration history in the US while straddling the Black-White racial binary. Despite their growing presence, research on South Asian mental health is relatively limited and often subsumed under the broader category of "Asian Americans," which obscures unique experiences due to the model minority myth and leads to a paucity of targeted studies, particularly in the U.S. Mental health outcomes, specifically depression, self-harm and disordered eating behaviors are prevalent within this community, and are exacerbated after large-scale sociopolitical events due to increased discrimination. Limited studies examine the intersection of racism and mental health outcomes …

Psychiatric Morbidity In Perinatal Women And Its Outcome In A Tertiary Care Hospital, Lakshmi Velayudam, Prathap Talwar, Kishor M, Harshitha Padmanabha

Digital Journal of Clinical Medicine

Background: Pregnancy and postpartum are a period of vulnerability in a women’s life for developing mental health problems. Perinatal psychiatric illness has various adverse outcome on maternal, neonatal and child health.

Objective: To study the prevalence of psychiatric disorders and its outcome among women in the perinatal period.

Method: It is a prospective study conducted at a tertiary care hospital where antenatal and postnatal women were screened for psychiatric disorder using patient health questionnaire-9 (PHQ-9) and Edinburgh Post Natal Depression Scale (EPDS) respectively. Total of 140 women diagnosed with psychiatric disorder were followed up for a year and outcome …

Social Gender Norms And Depression In College Students, Derek Deeney

Masters Theses

The primary purpose of this quantitative study was to determine if there was a relationship between the conformity to social gender norms (masculine and feminine) and depression among male and female college students at a mid-sized, four-year public institution in the Midwest. A secondary purpose was to investigate if there was a difference in depression between males and females, and if a there was a difference in conformity to social gender norms (masculine and feminine) between males and females. Understanding the trends in social norm conformity and depression can lead to changes in how faculty and staff in higher education …

Witnessing Bullying And Internalizing Symptoms: The Influence Of Peer Relationships, Matthew Geisler

Graduate Research Theses & Dissertations

Bullying is a common problem in schools and has been associated with many different negative outcomes for students. While there has been considerable research examining students who are directly involved in bullying scenarios such as the bullies and victims themselves, less is known about the other students who witness bullying events at school. Bullying scenarios become more common at a similar time where peer relationships become more important in the daily lives of students as they begin to spend more time interacting with their peers. Positive peer relationships have been associated with positive outcomes for students and thus may serve …

Race-Based Stressors And Racial Trauma: The Moderating Role Of Parental Racial Socialization, Jessica S. Philip

Graduate Research Theses & Dissertations

Experiences of race-based stressors are linked with worse psychological outcomes for racial/ethnic minority individuals (e.g., Ferdinand et al., 2015). The way in which parents talk to their children about race (i.e., racial/ethnic socialization; RES) may exacerbate or buffer against the strength of this link (e.g., Keum & Ahn, 2021). Therefore, the present study examined the links between race-based stressors, RES, and psychological outcomes (i.e., depression, anxiety, stress, racial trauma) across multiple racial/ethnic minority groups. The present study also explored the different RES messages as potential moderators for the link between race-based stressors and outcomes, as well as differences in these …

Online Perceived Social Support And Its Association With Psychopathology In Rural And Urban Youth, Ellen Alexandra Knowles

Dissertations and Theses

Social support is a fundamental aspect of development throughout adolescence. It has been found to buffer against the negative impacts of stress and provide general benefits to one’s well-being. Youth today are exposed to a range of opportunities for socialization with peers, both in-person and online, including interacting with others through texting, social media, video games, and other digital means. These online interactions have begun to be investigated as accessible methods through which adolescents can connect with others and maintain healthy relationships. Furthermore, digital social networks may be most critical for youth from isolated communities, including those from rural areas. …

Facilitating Thought Progression To Reduce Depressive Symptoms: Randomized Controlled Trial, Shai-Lee Yatziv, Paola Pedrelli, Shira Baror, Sydney Ann Decaro, Noam Shachar, Bar Sofer, Sunday Hull, Joshua Curtiss, Moshe Bar

Psychology Faculty Publications

Background:

The constant rise in the prevalence of major depressive disorder calls for new, effective, and accessible interventions that can rapidly and effectively reach a wide range of audiences. Recent developments in the digital health domain suggest that dedicated online platforms may potentially address this gap. Focusing on targeting ruminative thought, a major symptomatic hallmark of depression, in this study we hypothesized that delivering a digital health-based intervention designed to systematically facilitate thought progression would substantially alleviate depression.

Objective:

The study aims to investigate the efficacy of a novel digital intervention on the reduction of depressive symptoms. This intervention was …

Lateralization Of Motor Behavior As A Measure Of Cognitive Functioning And Resting-State Electrocortical Activity, Alina Dillahunt

Master's Theses and Doctoral Dissertations

Background. Research has shown that the laterality between hands in self-report and motor measures maps onto hemispheric lateralization and this has important implications for psychopathology (e.g., depression) and cognition. The present study evaluates the relationship between performance on finger-tapping tasks (FTT), alpha power during resting-state electroencephalography (EEG), handedness, and relevant psychological outcomes. Methods. A sample of 48 individuals between the ages of 18 and 35 completed online assessments including a modified FTT paradigm, the Edinburgh Handedness Inventory, and a common depression measure. A subset of 20 participants completed assessments of motor and executive functioning including a self-report executive functioning measure, …

Impact Of Maternal Depressive Symptoms On Offspring Executive Functions: A Systematic Review, Júlia De Souza Rodrigues, María Pastor-Valero, Lucas R Trambaiolli, Ana Beatriz Bozzini, Alicia Matijasevich

Faculty, Staff and Student Publications

OBJECTIVE: To conduct a thorough examination of the current understanding of the effect of maternal depression exposure on the executive functions (EFs) of offspring.

METHODS: Following the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) statement, a comprehensive search for peer-reviewed cohort studies was performed on the MEDLINE (via PubMed), ScienceDirect, LILACS, PsycINFO, and SciELO databases. Study quality was assessed using the National Heart, Lung, and Blood Institute (NHLBI) Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. The evidence was evaluated using the Grading of Recommendation, Assessment, Development, and Evaluation framework.

RESULTS: Thirty-three cohort studies from different countries, …

The Effects Of Aerobic Exercise To Improve Depression In Overweight Adults, Curtis Lura

Master of Science in Nursing Family Nurse Practitioner

Overweight/obese adults are at an increased risk for both physical and mental comorbidities (CDC, 2019). Depression is a common comorbidity in those that are obese (CDC, 2019) and the standard of care currently to treat depression may increase the risk of physical comorbidities because weight gain is a common side effect of antidepressants (Hall-Flavin, 2018). The aim of this capstone research paper is to present evidence that an aerobic exercise regimen can be a valid treatment option for depression.

Unpredictable Positive Experience Response (Uper) Training In Male And Female Rats: Effects On Cognition, Emotional Resilience, And Neuroplasticity Markers, Eve M. Barringer

Honors Theses

This study investigated the effects of positive anticipation on depression-like symptoms in Long Evans male and female rats, using Unpredictable Positive Experience Response (UPER) training. Rats that received UPER training (UPER group) were exposed to cues followed by a positive reward at random times, fostering anticipation of three different positive experiences. Along with the UPER rats, there was a group of rats that received positive rewards without anticipation (ENR group) and a group that received no positive reward or anticipation (CTRL group). After 7 weeks of behavioral… training, we examined how training impacted the animal’s cognition, emotional resilience, and neurobiological …