Digital Commons Network^™

Implementation Of Depression Screening To Optimize Chronic Pain Management, Aaron B. Castle

Group: Northern Arizona University School of Nursing, DNP Doctoral Papers

Background: Chronic pain affects millions of people worldwide and the evidence demonstrates prevalent co morbidity of chronic pain and psychological issues such as anxiety, insomnia, and depression. The existence of psychological issues can have negative impact on pain management and compound the challenges inherent to successful management. Although clinical Practice Guidelines (CPG) recommend routine screening for depression, anxiety, and insomnia in all chronic pain patients, many primary care providers fail to routinely perform appropriate screening. The purpose of this project was to implement a practice change that would include screening for depression with chronic pain patients in a rural …

Iv Ketamine Infusions For The Treatment Of Depression: An Evidence Based Practice Analysis, Sergio A. Quinones

Group: Bryan College of Health Sciences Doctor of Nurse Anesthesia Practice (DNAP) Collection

According to the World Health Organization, major depressive disorder (MDD) is a mental health condition which affects a significant portion of the worldwide population and is projected to become the leading cause of disability by 2020. There are several treatment options for the diagnosis of depression, with the most popular being antidepressant drugs such as the selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs); and electroconvulsive therapy (ECT). The significant drawbacks to the current treatments are the extended timeframe required for drugs to reach therapeutic efficacy and resistance to ECT over time. These disadvantages can lead to increased risk …

Lower Urinary Tract Symptoms, Depression And Sleep Problems; A Triple Whammy For Patients’ Health-Related Quality Of Life, Muhammad Salman, Amer Hayat Khan, Syed Azhar Syed Sulaiman, Jeffery David Hughes, Junaid Habib Khan, Yusra Habib Khan, Tauqeer Hussain Mallhi

Bulletin of Faculty of Pharmacy Cairo University

Introduction: Lower urinary tract symptoms (LUTS) are characterized by voiding, storage and post-micturition symptoms. LUTS can have detrimental effects on various facets of patients’ quality of life. Therefore, this study was aimed to evaluate the association of LUTS with depression and sleep disturbances, and their impact on patients’ health-related quality of life (HRQOL).

Methods: A cross-sectional survey was conducted among a clinical sample of calcium channel blocker-users (n = 410), recruited via convenient sampling. Outcomes were assessed using validated Urdu translated instruments [LUTS: International Prostate Symptom Score; sleep problems: Jenkins sleep evaluation questionnaire (JSEQ); depression: Center for Epidemiologic Studies Short …

Iron Deficiency And Internalizing Symptoms Among Adolescents In The National Health And Nutrition Examination Survey, Dimitri Fiani, Solangia Engler, Yang Ni, Sherecce Fields, Chadi Calarge

Faculty, Staff and Students Publications

Background: Iron Deficiency (ID) affects two billion people worldwide, predominantly adolescent girls, and may be associated with increased psychopathology. The associations between ID and symptoms of depression and anxiety in adolescents were examined using data from the National Health and Nutrition Examination Survey (NHANES), a cross-sectional survey of a nationally representative sample of non-institutionalized Americans.

Methods: The current analysis included survey cycles where both iron-related markers and mental health-related outcomes were collected in adolescents 12 to 17 years old. Acute and serious medical conditions, acute inflammation, and abnormal birth weight led to exclusion. Linear multivariable regression analyses examined the association …

Adverse Childhood Experiences Moderate The Association Between Sensory Processing Sensitivity And Depression, Grant Benham

Psychological Science Faculty Publications

Investigations of the link between personality and depression provide a path to identifying at-risk individuals and developing tailored treatment. Sensory processing sensitivity, reflecting individual differences in processing of internal and external stimuli, has been found to predict depression severity. Based on a diathesis-stress model, the present study examines whether this association is moderated by adverse childhood experiences. An online survey containing standardized measures of adverse childhood experiences, sensory processing sensitivity, and depression severity, was administered to 558 college students. The sample was predominantly Hispanic (92%) and female (70%) with a mean age of 20.2 years. In support of the diathesis-stress …

Evaluating The Difference Between Anxiety And Depression For Adults In The United States Who Were Adopted Internationally Versus Domestically, And Seeking To Determine If Age At Adoption Is A Predictor Of Depression And Anxiety For The Internationally Adopted, Kaitlyn Nicole Whiteside Engle

Doctoral Dissertations and Projects

There is a gap in research on if there is a difference in mental health in those internationally and domestically adopted into the United States. The purpose of this quantitative study is to evaluate if there is a difference in depression and anxiety levels in those adopted domestically versus those adopted internationally and to determine if age at adoption for those internationally adopted is associated with levels of anxiety and depression. The three research questions are is there a difference in anxiety and depression levels in those internationally versus domestically adopted, is there a difference in age at adoption between …

Exploring The Barriers Colleges Face Implementing Positive Psychology Interventions To Reduce Depression, Anxiety, Or Stress In College Students, Margaret U. Williams

Doctoral Dissertations and Projects

The purpose of this qualitative collective case study was to understand the barriers that colleges face implementing positive psychology interventions (PPIs) to reduce depression, anxiety, or stress (DAS) in college students. The problem was the lack of utilizing PPIs to reduce DAS in college students, despite increased reports of symptoms among this population. Several research studies have supported the use of PPIs to reduce. DAS in college students. However, no prior research was identified regarding barriers to initiating these interventions. The three research questions that guided this study were fueled by previous empirical studies that revealed three barriers to implementing …

Long Term Impact Of Covid 19 On Psychiatric Health And Quality Of Life In Recovered Patients, Preetika Baghel, Pradeep Kumar P C, Kishor M

International Journal of Health and Allied Sciences

Background: Covid-19 has a devastating impact on different dimensions of life, including health. Recent studies have highlighted the effects of prolonged Covid-19 symptoms on mental health.

Aim: This study aims to 1) assess psychiatric illness among individuals previously diagnosed with COVID-19 infection and treated on an inpatient basis, and 2) evaluate the quality of life of individuals with and without psychiatric illness.

Method: This hospital-based cross-sectional study was conducted at a tertiary care general hospital in South India and involved 200 patients with COVID-19 infection who received treatment through an inpatient facility. The study utilized a sociodemographic …

Evaluating The Accuracy And Concordance Of The Dmind Ai Application With A Renowned Depression Assessment Tool In Thai Adults, Solaphat Hemrungrojn, Kittipoch Saengsai, Pasit Jakkrawankul, Chanyanart Kiattiporn-Opas, Kantapat Chaichareenon, Arisara Amrapala, Kulvara Lapanan, Titipat Achakulvisut, Peerapol Vateekul, Natawut Nupairoj, Phanupong Phutrakool, Rapinpat Yodlorchai, Narin Hiransuthikul, Sarunya Hengprapom

Chulalongkorn Medical Journal

Background: In Thailand, the high prevalence of depression, particularly in rural areas with limited mental health services, poses significant challenges. Advanced technologies like digital phenotyping and artificial intelligence (AI), particularly Natural Language Processing (NLP) and Large Language Models (LLMs), offer promising solutions by analyzing digital data to detect early signs of depression.

Objective: This study evaluated the performance of the “Detection and Monitoring Intelligence Network of Depression (DMIND)” application, an AI-powered screening tool for detecting depression in Thai adults that analyzes behavioral data from participant responses using machine learning algorithms, such as NLP models and LLMs. The study aimed to …

Voices From The Classroom: A Qualitative Study Of Teachers' Perspectives On Student Depression, Naomi Brinton, Jacqlyn Zarabba, Linda Mcwhorter, Linda Knauss

Journal of Human Services: Training, Research, and Practice

Rising levels of depression among adolescents is an important issue to teachers and school administrators, as teenagers spend the majority of their time in the school environment. By analyzing individual interviews with 15 public high school teachers using a modified grounded theory approach, this qualitative study examines the role high school teachers might play in identifying and referring students who exhibit signs and symptoms of depression. Results provide guidance for high school teachers in connecting students with appropriate services and identifying common barriers and facilitating factors in this process. Specific recommendations are outlined to help aid schools in the identification …

Identifying Adolescent Depression In The Public School System, Laura Lee Griffith

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Twenty percent of United States adolescents experience major depression at some point. Elevated school dropout rates, substance abuse, chronic disease, mortality and morbidity rates, and impaired growth remain because 60 % of adolescents with unidentified depression do not receive treatment. Purpose: This evidence-based project identified adolescents aged 16-19 in a South Carolina high school who had symptoms of depression. Counseling and resource information were provided for students with scores of 10 or greater, or thoughts of self-harm on the PHQ-9. Method: Students were screened using the PHQ-9. Data was organized in Excel and analyzed using the T-tests and …

Depression In Individuals With Chronic Liver Disease: Improving Screening In The Outpatient Setting, Kayla Corine Wright

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Individuals with chronic conditions such as chronic liver disease experience higher rates of depression, often underdiagnosed and placing high risk demographics in jeopardy of adverse outcomes, including worsening prognosis, decreased quality of life, and increased symptomatology.

Purpose: Evidence advocates for routine depression screening within high-risk patient populations. This paper outlines the implementation of a quality improvement initiative aimed at enhancing depression screening at a selected outpatient liver clinic within an extensive hospital system by implementing the PHQ-9 questionnaire during patient clinic visits, where no standardized screening protocol was previously in place.

Methods: The Plan-Do-Study-Act cycle guided the implementation …

Mitochondrial Function In The Maternal Brain: A New Perspective On Gestational Stress And Pathology Of Postpartum Depression, Erin Rene Gorman-Sandler

Theses and Dissertations

Postpartum depression (PPD) is a major psychiatric complication of childbirth, affecting up to 20% of mothers, yet remains understudied. Mitochondria, dynamic organelles crucial for cell homeostasis and energy production, share links with many of the proposed mechanisms underlying PPD pathology. Brain mitochondrial function is affected by stress, a major risk factor for development of PPD, and is linked to avoidance and social behaviors. Considering the importance of mitochondria in regulating brain function and behavior, we hypothesized that mitochondrial dysfunction is associated with behavioral alterations in a chronic stress-induced rat model of PPD. Chronic mild unpredictable (CMUS) stress during late gestation …

Lps-Induced Whole-Blood Cytokine Production And Depressive Symptoms In Dementia Spousal Caregivers: The Moderating Effect Of Childhood Trauma, Daniel L Argueta, Kelly N Brice, E Lydia Wu-Chung, Michelle A Chen, Vincent D Lai, Jensine Paoletti-Hatcher, Bryan T Denny, Charles Green, Luis D Medina, Paul Schulz, Jennifer Stinson, Cobi Heijnen, Christopher P Fagundes

Faculty, Staff and Student Publications

Dementia spousal caregivers are at risk for adverse mental and physical health outcomes. Caregiver burden, anticipatory grief, and proinflammatory cytokine production may contribute to depressive symptoms among caregivers. People who report childhood trauma are more likely to have exaggerated stress responses that may also contribute to depressive symptoms in adulthood. This study aimed to test whether the relationship between whole-blood cytokine production and depressive symptoms is strongest in caregivers who report high levels of childhood trauma.

Methods: A sample of 103 dementia spousal caregivers provided self-report data on demographics, health information, caregiver burden, anticipatory grief, and depressive symptoms. We also …

Homoeopathy In Bipolar Affective Disorder: A Review Of Research Evidence, Deepthi Gilla, K.P. Deepak, Sreeja Kr Nair, K.C. Muraleedharan

Indian Journal of Research in Homoeopathy

Background: Bipolar affective disorder (BPAD) is an episodic, chronic psychiatric disorder characterized by fluctuations in mood state and energy. It affects more than 1% of the world’s population. BPAD causes cognitive and functional impairment and raised mortality, particularly death by suicide. At present, although alternative therapies are not the first-line treatment of mood disorders, there is emerging evidence showing that such treatments are effective. Objective: The objective of this review is to synthesize existing research evidence and literature to determine the usefulness of homoeopathic medicines in the management of manic and depressive episodes of BPAD. Materials and Methods: Two authors …

Investigating The Role Of Mental Imagery Use In The Assessment Of Anhedonia, Julie L Ji, Marcella L Woud, Angela Rölver, Lies Notebaert, Jemma Todd, Patrick J F Clarke, Frances Meeten, Jürgen Margraf, Simon E Blackwell

School of Psychology

Anhedonia, or a deficit in the liking, wanting, and seeking of rewards, is typically assessed via self-reported "in-the-moment" emotional and motivational responses to reward stimuli and activities. Given that mental imagery is known to evoke emotion and motivational responses, we conducted two studies to investigate the relationship between mental imagery use and self-reported anhedonia. Using a novel Reward Response Scale (adapted from the Dimensional Anhedonia Rating Scale, DARS; Rizvi et al., 2015) modified to assess deliberate and spontaneous mental imagery use, Study 1 ( N  = 394) compared uninstructed and instructed mental imagery use, and Study 2 ( N  = …

A Brief Review Of Zuranolone, Aubrey A. Jackson

Transformative Medicine

Zuranolone, a novel analog of allopregnanolone, has been approved by the U.S. Food and Drug Administration (FDA) as the first oral medication approved for the treatment of postpartum depression in adults. Developed by Sage Therapeutics under the brand name Zurzuvae, zuranolone was approved by the FDA on August 4^th, 2023.¹ Zuranolone is a modified version of brexanolone (sold under the brand name Zulpresso), an intravenously administered allopregnanolone formulation that was previously the only FDA-approved medication for postpartum depression. Zuranolone offers a more accessible treatment option for patients with efficacy established in clinical trials. Its approval expands the …

Mental Health During The Covid-19 Pandemic In Trinidad: An Analysis Of Depression, Anxiety, And Stress Among Essential Workers, Bernadette Marson, Gerard A. Hutchinson

Journal of Social, Behavioral, and Health Sciences

Research shows that some essential workers, such as healthcare workers, social workers, and first responders (including police officers, paramedics, and firefighters), are at greater risk for developing both short- and long-term mental health problems (Berger et al., 2012; Canady, 2022; Grey et al., 2020; Haugen et al., 2012; Mohamed et al., 2022; Petrie et al., 2018). The most prevalent of these include anxiety, depression, and stress, as well as other social and cognitive problems—with stress causing harmful effects on mental health and potentially resulting in anxiety and depression, which may then disrupt an individual’s social relationships, family life, and work. …

Communication And Posttraumatic Growth: The Power Of Positive Declarations, Jennifer L. Owen

Doctoral Dissertations and Projects

Research has explored the relationship between posttraumatic growth (PTG) and communication trends. Yet, there is a gap in research regarding how positive declarations of desired outcomes can influence PTG and be applied in a therapeutic context. The purpose of this quantitative study was to examine if positive declarations of psychological growth facilitate PTG after trauma and impact levels of hope, anxiety, or depression. A small pilot study was conducted through six counseling sessions with participants (N = 16) divided into either the control (n = 8) or experimental group (n = 8). A novel Positive Communication Approach (PCA), distinguished by …

Screening For Depression Post Acute Coronary Syndrome, Alyssa Graham

Dissertations

Background: Acute coronary syndrome (ACS) and depression have profound impacts on patient outcomes. Patients who experience ACS are at increased risk of developing depression, which is associated with an increased risk of death and recurrent cardiac events. The evidence following ACS events promotes routine depression screening. The purpose of this project was to identify early depression in patients 65-99 years of age who had a recent diagnosis of ACS during their hospitalization.

Methods: This quality improvement (QI) project was a prospective descriptive observational design implementing a depression screening protocol to evaluate post-ACS referrals within 7-14 days of screening from February …

Clinical Correlates Of Perceived Stigma Among People Living With Epilepsy Enrolled In A Self-Management Clinical Trial, Martha Sajatovic, Martha Sajatovic, Jessica Black, Jacqueline Krehel-Montgomery, Grace Mcdermott, Joy Yala, Richard Barigye, Clara Adeniyi, Farren Briggs

Faculty Scholarship

Background and Purpose: Stigma is a pervasive barrier for people living with epilepsy (PLWE) and can have substantial negative effects. This study evaluated clinical correlates of perceived stigma in a research sample of PLWE considered to be at high risk due to frequent seizures or other negative health events. Methods: Analyses were derived from baseline data from an ongoing Centers for Disease Control and Prevention (CDC)-funded randomized controlled trial (RCT) testing an epilepsy self-management approach. Standardized measures assessed socio-demographics, perceived epilepsy stigma, epilepsy-related self-efficacy, epilepsy self-management competency, health literacy, depressive symptom severity, functional status, social support and epilepsy-related quality of …

Animation As Therapy For Mental Health Treatment Across Diverse Populations And Contexts, A Literature Review, Daneile Tabana

Expressive Therapies Capstone Theses

Scientific research has explored and identified the beneficial relationship between health and creative expression, recognizing art therapy as a source of healing. Animation has been newly recognized as an art therapy medium with potential for therapeutic healing and increased psychological well-being. This review of the literature on animation therapy explores the history of the modality’s interaction with the population observed and the effects of animation on the cognitive processes, discusses current theoretical orientations and treatment options for treating a range of conditions that affect mood, thinking, and behavior with animation therapy, and considers culturally informed and client-centered practices alongside traditional …

The Prevalence Of Depression And Anxiety In Patients With Metastatic Disease To The Spine, Caleb Yeung, Jeremy Heard, Yunsoo Lee, Michael Mccurdy, Rajkishen Narayanan, Samantha Kolowrat, Liam Gibbons, Tim Hagan, Jose A. Canseco, Alan S. Hilibrand, Alex R. Vaccaro, Gregory D. Schroeder, Christopher K. Kepler

Rothman Institute Papers

Introduction:

The prevalence of depression and anxiety in cancer patients is approximately 15% and 20%. Unfortunately, depression has been demonstrated to negatively impact patients after spinal fusion surgeries and is associated with worse overall survival in cancer patients. The rates of depression and anxiety have yet to be reported in patients with metastatic spine disease. The objective of this study was to determine the rate of depression and anxiety in patients with metastatic spine disease.

Materials and Methods:

Patients >18 years of age at our institution who presented with metastatic spinal disease between 2017 and 2022 were identified through query …

“Quacking For Noggin”: Farm Animal–Assisted Therapy For Traumatic Brain Injury Survivors, Alex Sargsyan, Lora Beebe, Zenithson Ng, Patricia Roberson, Sandra Thomas

People and Animals: The International Journal of Research and Practice

The aim of this study was to examine the effects of animal-assisted therapies with farm animals (AATF), in this case domesticated ducks, on depression, anxiety, and self-efficacy in patients with traumatic brain injury (TBI). Furthermore, the following hypothesis was tested:

Engaging in AATF with domesticated ducks will be associated with decreased depression, decreased anxiety, and increased self-efficacy.

The study examined the effects of AATF on anxiety, depression, and self-efficacy among nine patients with TBI. A time series quasi-experimental design was utilized. Participants completed the Hospital Anxiety and Depression Survey (HADS) and General Self-Efficacy (GSE) questionnaires at baseline, followed by the …

Complications And Healthcare Cost Of Total Hip Arthroplasty In Patients With Depressive Disorder, Antoinette R Portnoy, Shirley Chen, Ameer Tabbaa, Matthew L Magruder, Kevin Kang, Afshin E Razi

SKMC Student Presentations and Publications

PURPOSE: The purpose of this study was to determine whether the rates of (1) in-hospital lengths of stay (LOS), (2) readmissions, (3) medical complications, and (4) costs of care are higher for patients with depressive disorder (DD) undergoing primary total hip arthroplasty (THA) for treatment of femoral neck fractures (FNFs).

MATERIALS AND METHODS: A retrospective query of a national administrative claims database for patients undergoing primary THA from 2006 to 2014 was conducted. Patients with DD undergoing THA for treatment of FNF were 1:5 ratio propensity score matched to a cohort (DD=6,758, controls=33,708). Primary endpoints included LOS, 90-day medical complications, …

Stereo-Electroencephalography-Guided Network Neuromodulation For Psychiatric Disorders: The Neurophysiology Monitoring Unit, Anusha B Allawala, Kelly R Bijanki, Joshua Adkinson, Denise Oswalt, Evangelia Tsolaki, Sanjay Mathew, Raissa K Mathura, Eleonora Bartoli, Nicole Provenza, Andrew J Watrous, Jiayang Xiao, Victoria Pirtle, Madaline M Mocchi, Sameer Rajesh, Nabeel Diab, Jeffrey F Cohn, David A Borton, Wayne K Goodman, Nader Pouratian, Sameer A Sheth

Faculty, Staff and Students Publications

Background and objectives: Recent advances in stereotactic and functional neurosurgery have brought forth the stereo-electroencephalography approach which allows deeper interrogation and characterization of the contributions of deep structures to neural and affective functioning. We argue that this approach can and should be brought to bear on the notoriously intractable issue of defining the pathophysiology of refractory psychiatric disorders and developing patient-specific optimized stimulation therapies.

Methods: We have developed a suite of methods for maximally leveraging the stereo-electroencephalography approach for an innovative application to understand affective disorders, with high translatability across the broader range of refractory neuropsychiatric conditions.

Results: This article …

The Performance Relationship Between The Eq-5d-5l Composite "Anxiety/Depression" Dimension And Anxiety And Depression Symptoms In A Large, General Population Sample, Emily Stella Scott, Erica I. Lubetkin, Mathieu F. Janssen, John N. Yfantopolous, Gouke J. Bonsel, Juanita A. Haagsma

Publications and Research

Purpose

This cross-sectional study aims to understand the relationship between responses on the Anxiety/Depression (A/D) dimension of the EQ-5D-5L and symptoms of anxiety and depression on the GAD-7 and PHQ-9 instruments. In doing so, we investigate the comparative performance of the dimension between diagnostic groups (i.e. anxiety (GAD-7); depression (PHQ-9); anxiety & depression versus none). We additionally investigate the discriminatory performance between sub-populations based on gender, age, education and self-reported chronic conditions.

Methods

19,902 general population participants completed a health survey in May/June 2020, from five European countries and the United States. Performance of A/D was calculated using the Area …

Depressive Symptoms And Sleep Quality Mediate The Relationship Between Race And Quality Of Life Among Patients With Heart Failure: A Serial Multiple Mediator Model, Jia-Rong Wu, Debra K. Moser, Chin-Yen Lin, Ambrose A. Chiang, Barbara Riegel

UK CARES Faculty Publications

Background: Black patients with heart failure (HF) report worse quality of life (QoL) than White patients. Few investigators have examined mediators of the association between race and QoL, but depressive symptoms and sleep quality are associated with QoL.

Objective: The aim of this study was to determine whether depressive symptoms and sleep quality are mediators of the relationship between race and QoL among patients with HF.

Methods: This was a cross-sectional study. We included 271 outpatients with HF. Self-reported race (White/Black), depressive symptoms (Patient Health Questionnaire), sleep quality (Pittsburgh Sleep Quality Index), and QoL (Kansas City Cardiomyopathy Questionnaire) were collected …

Nuanced Relationships Between Indices Of Smartphone Use And Psychological Distress: Distinguishing Problematic Smartphone Use, Phone Checking, And Screen Time, Yue Qi Germaine Tng, Hwajin Yang

Research Collection School of Social Sciences

Recent theoretical and empirical accounts maintain that different indices of smartphone use—including problematic smartphone use, phone-checking, and screen time—tap distinct facets of smartphone use. This highlights the importance of disentangling potentially unique associations between facets of smartphone use and psychological distress outcomes. The present study examined fine-grained relationships between several smartphone-use indices and facets of psychological distress. Further, we probed whether sex modulated the relationships between smartphone-mediated behaviours and distress outcomes. Using structural equation modelling, we analysed data from young adults (N = 364) and evaluated the associations of smartphone-related behaviours—problematic use, phone checking, and overall screen time—with depression, anxiety, …

Resting-State Eeg Microstate Features For Major Depressive Disorder Classification, George M. V. Quinn

Dissertations, Theses, and Capstone Projects

Neuroimaging studies have revealed consistent abnormalities in functional connectivity within specific neural networks that may serve as biomarkers for major depressive disorder (MDD). It is important to find inexpensive, non-invasive techniques that target these biomarkers to make diagnosis easier and more objective. EEG microstates are quasi-stable potential topographies that are thought to reflect the quasi-stable network activity of the underlying neural generators. MDD has been shown to alter features of the four canonical EEG microstates (A, B, C, D) with some conflicting results. The most consistent network abnormalities in MDD are found in the anterior default mode network, and this …