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Articles 301 - 330 of 4410
Full-Text Articles in Entire DC Network
Impact Of Perceived Stress And Trait Resilience On Mental Health Outcomes Related To Traumatic Stress Exposure, Ken Safley
Clinical Psychology Dissertations
Traumatic stress exposure is common and associated with a range of adverse psychological outcomes, including anxiety, depression, and posttraumatic stress disorder (PTSD). These effects are cumulative, with increased exposure linked to greater psychological distress. However, there is considerable variability in how individuals respond to trauma, suggesting the influence of cognitive and dispositional factors. Cognitive models of PTSD highlight the role of stressor appraisals in the development of psychopathology, while individual differences in protective factors, such as trait resilience, may buffer these effects. The present study investigated whether perceived stress mediates the relationship between trauma exposure and psychological outcomes, and whether …
Effectiveness Of Digital Behavioral Activation Interventions For Depression And Anxiety: Systematic Review And Meta-Analysis, Eric Jia, Jushawn Macon, Michelle Doering, Joanna Abraham
Effectiveness Of Digital Behavioral Activation Interventions For Depression And Anxiety: Systematic Review And Meta-Analysis, Eric Jia, Jushawn Macon, Michelle Doering, Joanna Abraham
2020-Current year OA Pubs
BACKGROUND: As digital interventions gain prominence in mental health care, they present opportunities to improve access and scalability. Despite their potential, the overall impact of digital behavioral activation (BA) interventions across different formats and populations is not yet fully understood.
OBJECTIVE: This systematic review examines the characteristics and functions of digital BA interventions and evaluates their effectiveness for mental health and other patient-related outcomes.
METHODS: A comprehensive search of databases (PubMed, Embase, Web of Science, APA PsycInfo, and ClinicalTrials.gov) was performed in November 2023 to identify randomized controlled trials (RCTs) assessing the effectiveness of digital BA interventions for depression and …
Electro Transcranial Magnetic Stimulation (Etms) Effects On Pharmacoresistent Sleep Disorders Using A Quantitative Electroencephalogram (Qeeg), Sarah Diane Dean
Electro Transcranial Magnetic Stimulation (Etms) Effects On Pharmacoresistent Sleep Disorders Using A Quantitative Electroencephalogram (Qeeg), Sarah Diane Dean
Doctoral Dissertations and Projects
The following quantitative correlational study investigated the effects of eTMS on individuals with pharmacoresistant sleep disorders using a qEEG. This research measures the dimensions of anxiety, depression and quality of life (QoL) as it relates to untreated secondary diagnosis. Additionally, this research examines the activity level of the dorsolateral prefrontal cortex in relation to eTMS treatments. It was found that correlation with anxiety (rs = -.466, p < .001), depression (rs = -0.556, p < 0.001), quality of life (rs = -.436, p < .001), and sleep disturbances (rs = -0.452, p < 0.001), have a statistically significant negative correlation with dlPFC activity level. Finally, it was found that eTMS does have a statistically significant relationship with sleep disturbances as well as anxiety, depression and general quality of life (U (195) = 4647, p = .971). This is important to the field of neuroscience as it provided a more precise form of individualized neuromodulation through the use of a uncommon type of transcranial magnetic stimulation.
A Phenomenological Exploration Of The Church In The Healing Process For African American Women In The Washington, D.C., Area Suffering From Self-Diagnosed Depression In Recovery From Intimate Partner Violence, Kimberly D. Brooks
Doctoral Dissertations and Projects
The purpose of this descriptive phenomenological study is to describe the lived experiences of African American women who have utilized the church after intimate partner violence (IPV) suffering self-diagnosed depression in the Washington, D.C. area. The approach guiding the methodology of this study is Clark Moustakas’ (1994) phenomenological approach. There is a need to explore what type of support the church offers as a source of healing for those who need assistance and will not seek professional counseling for various reasons. While there has been much research on depression resulting from IPV, there is a gap in the literature regarding …
Longitudinal Relations Between Self-Esteem And Depression: A Continuous Time Analysis With Exploration Of Sleep Duration Effects, Mackenzie Cummings
Longitudinal Relations Between Self-Esteem And Depression: A Continuous Time Analysis With Exploration Of Sleep Duration Effects, Mackenzie Cummings
Clinical Psychology Dissertations
Adolescents and young adults face elevated risk for depression. While poor self-esteem and sleep disturbance are known risk factors, few studies have examined their unique and interactive contributions. Longitudinal research often overlooks unequal intervals and multiple sources of variance (e.g., between- and within-person). This study used continuous time structural equation modeling to address these gaps and examine relationships between self-esteem, sleep duration, and depression from adolescence into adulthood. Drawing on four waves of data from the National Longitudinal Study of Adolescent to Adult Health (N = 6,184), I tested whether sleep duration moderated the self-esteem–depression link and explored gender differences. …
Family-Based Support As A Social Determinant Of Health-Protective Factor For Children With Autism Spectrum Disorder, Bisola Duyile, Naomi J. Wheeler
Family-Based Support As A Social Determinant Of Health-Protective Factor For Children With Autism Spectrum Disorder, Bisola Duyile, Naomi J. Wheeler
Department of Counseling Scholarship and Creative Works
Parents of children with autism spectrum disorder (ASD) demonstrate resilience and resourcefulness in managing the demands of caregiving. This study highlights the critical role of family based support as a social determinant of health-protective factor (SDHPF) that enhances the well-being of parents, helping to mitigate depressive symptoms. Using a secondary dataset of 199 parents/ caregivers of children with ASD, this study examines how family based support, child symptom severity, and financial resources (income) influence parental mental health. The findings show that strong family support is positively associated with lower levels of depression, underscoring the strength of social networks in enhancing …
Evaluating Depression In Adults Undergoing Substance Abuse Treatment: A Program Evaluation Of Intensive Outpatient Program, Chidochomoyo E. Zvirawa
Evaluating Depression In Adults Undergoing Substance Abuse Treatment: A Program Evaluation Of Intensive Outpatient Program, Chidochomoyo E. Zvirawa
Dissertations
Problem: Depression and substance use disorders (SUDs) frequently co-occur, complicating recovery outcomes. Despite screening recommendations, depression remains underdiagnosed in many SUD treatment settings.
Methods: This mixed-methods program evaluation examined depressive symptoms among adults in an Intensive Outpatient Program (IOP) using the Patient Health Questionnaire (PHQ-8). Depression screenings were conducted at intake, four weeks, and eight weeks. Eight participants meeting inclusion criteria were assessed. Data included demographics, treatment engagement, and PHQ-8 scores.
Results: PHQ-8 scores significantly declined from baseline (M = 11.75, SD = 6.52) to eight weeks (M = 5.13, SD = 5.05), t(7) = 2.76, p = .028, indicating …
Relationship Between Emotional Intelligence And Well-Being Among New York Police Department Law Enforcement Agents, La’Lisa Scudder
Relationship Between Emotional Intelligence And Well-Being Among New York Police Department Law Enforcement Agents, La’Lisa Scudder
Walden Dissertations and Doctoral Studies
The problem this quantitative study addressed was police officers’ willingness to use organizational help-seeking interventions and rely on organizational support to mitigate operational and organizational stress. Previous literature discussed how officers engaged in different maladaptive coping behaviors as a result of work related stressor or low well-being, divorce, depression, prescription drug abuse, alcoholism, and suicide. The purpose of this quantitative correlational cross-sectional study was to examine the relationship between emotional intelligence and well-being among law enforcement agents and examine agents’ willingness to use organizational-based intervention services. The organizational support theory and the social exchange theory provided the theoretical framework for …
Unseen Burdens: Exploring Gender Disparities In Infertility Experience And Depressive Symptoms, Khiara Cardoza Brown
Unseen Burdens: Exploring Gender Disparities In Infertility Experience And Depressive Symptoms, Khiara Cardoza Brown
Theses and Dissertations
This study examines how experiences with infertility relate to mental health outcomes among newly married U.S. couples, emphasizing gender differences and the potential moderating role of gender attitudes. Using data from 3,137 individuals in a nationally representative sample, three Actor-Partner Interdependence Models were estimated: first assessing actor and partner effects of infertility on depressive symptoms and subsequently incorporating gender attitudes as moderators. Results indicated a significant actor effect for wives, where infertility was associated with higher levels of depressive symptoms, and this association was significantly stronger for wives than for husbands. No significant effects were found for husbands' infertility and …
Predictors Of Nursing Students' Stress, Anxiety, And Depression During The Covid-19 Pandemic In A Hispanic-Serving University In South Texas: A Cross-Sectional Study, Maria I. Diaz, Eleftherios Gkioulekas, Nancy Nadeau
Predictors Of Nursing Students' Stress, Anxiety, And Depression During The Covid-19 Pandemic In A Hispanic-Serving University In South Texas: A Cross-Sectional Study, Maria I. Diaz, Eleftherios Gkioulekas, Nancy Nadeau
School of Mathematical & Statistical Sciences Faculty Publications
Background: In nursing education, there have been several studies on the impact of the COVID-19 pandemic on the ability of nursing students to cope while in nursing school.
Purpose statement: The goal of this study is to assess undergraduate nursing students' support mechanisms as predictors of stress, anxiety, and depression during the COVID-19 pandemic within a Hispanic-serving institution in South Texas.
Methods: Across-sectional design was used in this study. An online survey using self-reported questionnaires was used to gather data from an undergraduate nursing student cohort during the Fall 2021 semester. Linear regression was used to identify the predictors of …
More Than Hormones: Psychological Consequences Of The Medicalized Menopausal Experience, Haley Derrickson
More Than Hormones: Psychological Consequences Of The Medicalized Menopausal Experience, Haley Derrickson
University Honors Theses
Menopause, a transitional period that roughly half the population may experience, has a high degree of variability in onset and intensity of symptoms, one of which is depression. It is also a period in which the lives of those transitioning are highly medicalized. This literature review investigates how medicalization has increased since the term was created, and how it impacts perimenopause, menopause, and mental health.
Social Media, Religion, And Anxiety: Comparison Of Age Groups, Kaye Eileen Redeker
Social Media, Religion, And Anxiety: Comparison Of Age Groups, Kaye Eileen Redeker
Doctoral Dissertations and Projects
Social media has become an integral part of daily life for all age groups. The current research is mixed, showing both positive and negative effects from social media on mental health. This study aimed to examine how the duration of social media use compared with anxiety levels, and if religiosity had any effect on social media use and anxiety. It also wanted to determine if there was a correlation between religiosity and social media use, and how social media use and religiosity predicted anxiety. This study filled a gap in research by extending previous studies beyond adolescents and by including …
A Qualitative Study On Investigating The Power Of Scripture To Conquer Depression By The Bible's Psychological Power Among Christians, Joana Okudzeto Biekro
A Qualitative Study On Investigating The Power Of Scripture To Conquer Depression By The Bible's Psychological Power Among Christians, Joana Okudzeto Biekro
Doctoral Dissertations and Projects
This phenomenological study investigated Evangelical Christians’ experiences using the Bible as a means of treating their depression in Orange County, CA. Depression is a painful mental illness that affects people all over the world. The rationale of the study is to add knowledge to Christians and thought leaders who seek a cure to the struggle of depression from a Biblical perspective. The research process is presented in the study of depression among Christians. Guided by these three questions, “How do evangelical Christians describe their experiences using the Bible as a means of treating their depression?”, “How do participants describe their …
The Moderating Effects Of Adult Attachment And Emotional Intimacy On The Relationship Between Aces And Mental Health In Social Work Students, Cheryl Lind Nitz
The Moderating Effects Of Adult Attachment And Emotional Intimacy On The Relationship Between Aces And Mental Health In Social Work Students, Cheryl Lind Nitz
Doctoral Dissertations and Projects
Social work students report significantly more adverse childhood experiences (ACEs) than other majors or the general population. ACEs increase the risk of depression, anxiety, and stress (DAS) and can impact students’ ability to effectively serve future clients. Attachment theory and current research suggest a substantial potential therapeutic impact of secure adult attachments, particularly those with high emotional intimacy (EI), for those with ACEs. This study explored the moderating effect of primary adult attachment (PAA) on the relationship between ACEs and mental health. The Adverse Childhood Experiences (ACE-10) Scale, the State Adult Attachment Measure (SAAM), the Functional Analytic Psychotherapy Intimacy Scale …
Increasing Depression Risk Screening In Hospice And Palliative Care Patients, Elizabeth Kanini Michaels
Increasing Depression Risk Screening In Hospice And Palliative Care Patients, Elizabeth Kanini Michaels
Walden Dissertations and Doctoral Studies
This doctoral project was conducted as a staff education project. The practice problem involved inconsistent depression risk screening in hospice and palliative care patients. It was crucial to address this, as depression can be pervasive in this population. The practice-focused question was, For registered nurses who work in a palliative or hospice care unit, does education on depression risk screening increase depression screening rates as compared 12 weeks before to 12 after the education? The project aimed to improve depression risk screening rates through staff education. The Johns Hopkins nursing evidence-based practice model was used to assess 13 supporting articles …
School-Based Mental Health Practice: The Impact Of Physical Activity On Depression, Nafees Alam, Joy Krug
School-Based Mental Health Practice: The Impact Of Physical Activity On Depression, Nafees Alam, Joy Krug
Social Work Faculty Publications
The relationship between physical and mental health has long been theorized to be profoundly important in understanding human behavior and development. This article aims specifically to highlight the state of existing research about the relationship between physical activity and the state of depression. Studies across the nation, summarized here, have found that healthy physical activity levels generally correlate with health within the mental and emotional arenas. Despite the abundance of existing literature on this topic, research remains scarce on the longitudinal effects of physical activity beginning with pre-puberty children into adulthood. Physical activity is a relatively cheap and non-harmful lifestyle …
Sense, Drugs, And Rock 'N' Roll: A Critical Review Of Music And Psychedelic Literature, Sophia Harper-Hague
Sense, Drugs, And Rock 'N' Roll: A Critical Review Of Music And Psychedelic Literature, Sophia Harper-Hague
Expressive Therapies Theses
The use of psychedelics has been shown promising efficacy surrounding treatment-resistant mental health diagnoses, as well as improving quality of life for those not suffering from mental health conditions. Additionally, music has been seen as a significant part of psychedelic research, both by music therapists and other allied health professionals alike. This literature review explores the current research surrounding music therapy and psychedelic approaches, as well as the areas in which they intersect. The current review focuses on Post-traumatic Stress Disorder (PTSD), depression, anxiety, and self-concept, delving into the perceptions of both music and psychedelic therapy as emerging treatment options …
How Does An Art Therapist Build Rapport With Socially Isolated Older Adults?, Elizabeth L. Levering
How Does An Art Therapist Build Rapport With Socially Isolated Older Adults?, Elizabeth L. Levering
Expressive Therapies Theses
This study was done to explore the fundamental aspects that are woven into the report-building process and the therapeutic alliance with socially isolated older adults. Research has been done on the effects that social isolation and loneliness have on this underserved population, however report building is less researched and can be translated into the mental health field. Person-centered therapy, developmental stages of older adults, and the growing field of art therapy and its benefits are also well documented. This qualitative arts-based study takes the intersectionality of these topics by observing three sessions with two separate residents and analyzing the results. …
Depression And Anger In Male Adolescents: A Cognitive Behavioral Group Manual, Ellen Nichole Lindquist
Depression And Anger In Male Adolescents: A Cognitive Behavioral Group Manual, Ellen Nichole Lindquist
Dissertations, Theses, and Projects
Depression is a common mental health disorder experienced by children and adolescents. Depression in male adolescents often does not follow the DSM criteria as it does in girls. This literature review and manual will explore gender differences in the manifestation of depression symptoms, as well as the link between depression and anger in adolescent males. Additionally, effective treatments for depression and anger will also be explored. Treatment approaches include cognitive behavioral therapy (CBT), dialectical behavior therapy (DBT), and pharmacological treatments. This group manual provides evidence-based CBT interventions that are effective in managing and treating symptoms of major depressive disorder, especially …
Staff Education To Enhance Nurse Knowledge Of Depression And Screening Tool Using Patient Health Questionnaire-9, Oluwakemi Omotayo Aregbesola
Staff Education To Enhance Nurse Knowledge Of Depression And Screening Tool Using Patient Health Questionnaire-9, Oluwakemi Omotayo Aregbesola
Walden Dissertations and Doctoral Studies
Summary This staff education program focused on addressing a practice deficit regarding nonstandard depression assessment and substandard nurse knowledge of evidence-based screening tools, mainly the Patient Health Questionnaire-9 (PHQ-9), a nine-item, self-reporting test used to screen for depression and assess severity of the condition based on the Diagnostic and Statistical Manual of Mental Illnesses, 5th Edition. Depression exists as a familiar yet unidentified disorder among psychiatric inpatients, resulting in delayed treatment inferior outcomes. The staff education project targeted the nurses’ knowledge of depression identification while also teaching them to administer the PHQ-9 for prompt screening and intervention. I used an …
Mothers Supporting Mothers: A Psychotherapy Group For Postpartum Mothers Struggling With Substance Use, Brittany Hook
Mothers Supporting Mothers: A Psychotherapy Group For Postpartum Mothers Struggling With Substance Use, Brittany Hook
Educational Specialist, 2020-current
One topic that is not talked about enough is women’s health and more specifically postpartum women. This is apparent especially when it comes to postpartum care and the diverse experiences women face. The silence around postpartum women’s experiences can be frightening at times. The mental health of postpartum mothers can be overlooked and can lead to concerns of suicide ideation, increase substance use and a decrease in overall wellbeing. When substance abuse is in the picture for postpartum women, a treatment option that can be effective is group counseling. An evidence-based modality that works off the humanistic theory is motivational …
Comparing Deaf School And Mainstream Student-Athletes' Mental Health: Depression, Anxiety And Risk Factors, Ella Gamble
Comparing Deaf School And Mainstream Student-Athletes' Mental Health: Depression, Anxiety And Risk Factors, Ella Gamble
Undergraduate University Honors Capstones
The deaf community is diverse, including individuals from all different backgrounds. Sports are a large part of the community and are advocated for the deaf community. However, the mental impacts of sports within the deaf and hard of hearing (DHH) collegiate athlete population has received very little scholarly attention, especially in regards to their varying upbringings. Anxiety and depression are mental health issues (MHI) that have gained increasing attention in the hearing sports community, but this also extends to DHH student-athletes based on empirical evidence. This study focuses on the differences of MHIs in DHH student-athletes at Gallaudet University. The …
Pain Dismissal, Anxiety, Depression, And Substance-Use Coping In Emerging Adults With Chronic Pain, Elizabeth Felice Fenelon
Pain Dismissal, Anxiety, Depression, And Substance-Use Coping In Emerging Adults With Chronic Pain, Elizabeth Felice Fenelon
College of Science and Health Theses and Dissertations
Twelve percent of emerging adults (EA) experience chronic pain. Having one’s pain dismissed by others, or pain dismissal, is not uncommon and is isolating. There is already an established relationship between pain, anxiety, and depression; furthermore, pain dismissal exacerbates anxiety, depression, and substance-use coping. The current study explores pain dismissal’s relationship to anxiety, depression, and coping with substances. Undergraduate students with chronic pain (N = 227, age M = 19.58, SD = 1.42, range = 18-25) at a Midwestern university reported if they had pain, if their pain had been dismissed, as well as symptoms of anxiety, depression, and substance-use …
The Impact Of The Mediterranean Diet On Depression: A Narrative Review, Emma Kate Schaaf
The Impact Of The Mediterranean Diet On Depression: A Narrative Review, Emma Kate Schaaf
Honors Theses
Background. The Western diet has extensive negative ramifications on physical health and emotional well-being. The Mediterranean diet, widely regarded as one of the healthiest eating patterns in the world, may have the ability to improve psychological conditions. This study aims to examine existing research from randomized control trials (RCTs) on the association between depression prevalence and the Mediterranean diet.
Methods. The following review was conducted using PRISMA guidelines and the Google Scholar and PsycInfo databases. The criteria for inclusion were that studies: 1) were randomized control trials (RCTs) examining the Mediterranean diet; 2) included samples of adults (i.e., > 18 years …
Empathy And Psychological Outcomes In Informal Caregivers Of Community-Dwelling Older Adults: A Systematic Review And Meta-Analysis, Meng Huo, Thi Vu, Tomiko Yoneda, Jingkai Wei, Bruce Abbott, Joan K Monin
Empathy And Psychological Outcomes In Informal Caregivers Of Community-Dwelling Older Adults: A Systematic Review And Meta-Analysis, Meng Huo, Thi Vu, Tomiko Yoneda, Jingkai Wei, Bruce Abbott, Joan K Monin
Faculty, Staff and Student Publications
Objectives: Scholars have increasingly recognized the crucial role that empathy plays as informal caregivers provide unpaid care to their older family and friends (i.e., care recipients). Yet, the existing literature exhibits substantial variability in study approaches and results, which limits the extent to which this literature can inform interventions intended to benefit informal caregivers. We sought to address this critical gap by synthesizing research that examined how caregivers' and care recipients' empathy were associated with caregivers' psychological health.
Methods: We conducted a literature search using PubMed, PsycInfo, CINAHL (Cumulative Index to Nursing and Allied Health Literature), EMBASE, and Scopus databases …
Camouflaging Depression, Seth Brown
Camouflaging Depression, Seth Brown
Faculty Publications
Many individuals with depression have been observed to exert effort to appear non-depressed. This effort, referred to as camouflaging, has been systematically studied among individuals with autism spectrum disorder and attention deficit hyperactivity disorder, but not among individuals with more common disorders such as depression. The purpose of this research was to examine camouflaging amongst individuals with depression and develop a camouflaging instrument specifically for depression. The Camouflaging Depression Scale (CDS) was developed and administered to 292 individuals experiencing varying levels of depression along with other clinical measures. In this sample, engagement in camouflaging was common and similarly occurred among …
An Educational Intervention: Knowledge Acquisition Of Perimenopausal Mental Health Symptoms And Treatment Options For Women Aged 35 Years Plus, Allison M. Hopps
An Educational Intervention: Knowledge Acquisition Of Perimenopausal Mental Health Symptoms And Treatment Options For Women Aged 35 Years Plus, Allison M. Hopps
Doctor of Nursing Practice Scholarly Projects
Perimenopause is a span of four to six years preceding menopause when estrogen levels decline. Up to 40% of women experience depression during the perimenopause transition. Hormone replacement therapy (HRT) can be an effective treatment for depressive symptoms during perimenopause, but many healthcare practitioners prescribe antidepressants instead of HRT for the management of mood-related symptoms. Perimenopausal depression is associated with the progression of chronic conditions such as cardiovascular disease, diabetes, and dyslipidemia. The general population, including women and healthcare providers, lacks the education and awareness surrounding perimenopause symptoms and treatment. This project educated women between ages 35 to 55 on …
Counseling Guided Manual: Using Cbt To Reduce Media Addiction And Depression Symptoms, Grace Halverson
Counseling Guided Manual: Using Cbt To Reduce Media Addiction And Depression Symptoms, Grace Halverson
Dissertations, Theses, and Projects
This group manual is focused on media addiction, which is defined as the excessive and compulsive need to use any form of media despite negative consequences to people’s social, academic, and work life (Sherer, 2024). The focus of this group will be on people with internet and social media addiction. However, members will be able to self-report any form of media addiction. The members will self-report their depression symptoms. These symptoms will be assessed using Young’s Internet Addiction Test and Beck’s Depression Inventory-II on the first and last sessions to measure treatment effectiveness (Young, 2016) & (Beck et al., 1996). …
Parsing Heterogeneity In Depression, Kayla Hannon
Parsing Heterogeneity In Depression, Kayla Hannon
Arts & Sciences Graduate Student Theses and Dissertations
Depression is a highly prevalent mental health disorder that often requires treatment. While current treatments are effective for a large portion of patients generally, the exact medication that works for any specific person is unclear, leading to large delays in symptom remittance if at all. This hurdle has motivated substantial efforts to identify markers of depression that might predict treatment outcomes. However, large sources of heterogeneity in depression have stymied progress on identifying robust and replicable neuroimaging markers. Parsing this heterogeneity is crucial but mired with challenges. My dissertation work has elucidated several key barriers in parsing the heterogeneity of …
Investigating The Ability Of The Norepinephrine-Dopamine Reuptake Inhibitor Nomifensine To Reverse The Effort-Related Effects Of Tetrabenazine In Female Rats, Vivien Daytree
Honors Scholar Theses
Anergia, lassitude, and psychomotor retardation are core symptoms of motivational dysfunction that often accompany Major Depressive Disorder (MDD). While selective serotonin reuptake inhibitors effectively alleviate mood and anxiety symptoms, they remain relatively ineffective at alleviating motivational deficits. Compounds that elevate extracellular dopamine (DA) have shown promise in addressing these symptoms. Bupropion, a norepinephrine-dopamine reuptake inhibitor (NDRI), increases DA and is effective at attenuating motivational symptoms in patients. Another NDRI, nomifensine, has demonstrated potential antidepressant properties in preclinical research. Effort-based choice tasks, such as the FR5/chow choice task, serve as animal models for studying motivational dysfunction. Rats choose between exerting effort …