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Cognitive Factors And Treatment Adherence In Individuals With Cystic Fibrosis, Benjamin Edwin Burgess

All ETDs from UAB

Cystic fibrosis (CF) is a life-threatening chronic illness which requires adherence to a many complex and time-consuming treatments. Adherence is suboptimal in this population. Thus, it is important to consider predictors of treatment adherence. Research has evaluated a number of cognitive factors that are related to adherence in groups with chronic illnesses, including those with CF. The present study considers three factors (health locus of control (HLC), perceived social support, and perceived disease severity) in order to address important gaps in the literature evaluating their relationships with treatment adherence. For each of these factors, the current research is limited by …

The Relationship Between Demoralization And Depressive Symptoms Among Patients From The General Hospital: Network And Exploratory Graph Analysis, Martino Belvederi Murri, Rosangela Caruso, Heifa Ounalli, Luigi Zerbinati, Eleonora Berretti, Silvia Costa, Elisabetta Recla, Federica Folesani, David Kissane, Maria Giulia Nanni, Luigi Grassi

Medical Papers and Journal Articles

Introduction: Depression and demoralization are highly prevalent among individuals with physical illnesses but their relationship is still unclear.

Objective: To examine the relationship between clinical features of depression and demoralization with the network approach to psychopathology.

Methods: Participants were recruited from the medical wards of a University Hospital in Italy. The Demoralization Scale (DS) was used to assess demoralization, while the Patient Health Questionnaire-9 (PHQ-9) to assess depressive symptoms. The structure of the depression-demoralization symptom network was examined and complemented by the analysis of topological overlap and Exploratory Graph Analysis (EGA) to identify the most relevant groupings (communities) of symptoms …

Depression In Parkinson's Disease: Perspectives From An Australian Cohort, Michal Lubomski, Ryan L. Davis, Carolyn M. Sue

Medical Papers and Journal Articles

Introduction: Depression is often an under-recognised feature of Parkinson's disease (PD). It is detrimental to physical and interpersonal functioning, negatively impacting a patient's clinical management, quality of life and well-being. We aimed to identify clinical predictors and management implications of depression in Australian PD patients.

Methods: 103 PD and 81 Healthy Control (HC) subjects were evaluated using the Beck Depression Inventory (BDI) and other validated PD motor and non-motor symptom (NMS) tools.

Results: Nearly twice as many PD patients were depressed, (38.9% vs 20.1%, p = 0.009), with a corresponding increase in depression severity on the BDI (11.9; standard deviation …

Effects Of Depression And Health Habits On Diabetes Outcomes, Yvonne Marie Chapa

Walden Dissertations and Doctoral Studies

Diabetes mellitus outcomes are intensified by the lack of screening and awareness for depressive symptoms, alcohol consumption, cigarette use, and gender difference. The purpose of this quantitative survey study, grounded in biopsychosocial theory, was to investigate the best predictor (alcohol consumption, cigarette use, and the exploratory variable gender) of diabetes outcome in a Mexican American population. Data were collected using the Patient Health Questionnaire-9 with 120 Mexican American patients from a diabetic clinic in Southern Texas. Results from a multiple regression analysis indicated that gender was the best predictor. A series of Pearson correlations revealed a significant positive relationship between …

Epidemiology Of Marijuana Use And Mental Health In The Context Of Changing Policies, David G. Harvey Ii

Walden Dissertations and Doctoral Studies

There is a growing body of evidence supporting the association between cannabis use and the development of mental health disorders, but few studies have addressed this association following the recent increase in marijuana legalization laws. Therefore, using the social ecological model and the self-medication theory of addiction as theoretical frameworks, the purpose of this retrospective database study was to assess the relationship between marijuana use and major depression and suicidal ideation in both adults and adolescents in 2008 and 2017. Data from the National Survey on Drug Use and Health were analyzed using logistic regression at the p < .05 threshold for statistical significance. Results demonstrated positive, statistically significant relationships between marijuana use and both major depression and suicidal ideation for both adults and adolescents in both 2008 and 2017. Further, the strengths of these relationships generally increased between 2008 and 2017, coincident with the increase in marijuana legalization laws. These findings provide empirical support to the association between cannabis use and the development of mental health disorders, and that the strength of these associations is increasing following the increase in marijuana legalization laws. This study has important implication for positive social change by identifying significant relationships between cannabis use and the development of mental health disorders and revealing that these relationships are strengthening over time, coincident with the increase in marijuana legalization laws.

Exploring The Use Of Familismo To Manage Depression Among Elderly Latino Women, Denise Ramos

Walden Dissertations and Doctoral Studies

As the elderly population continues to increase in the United States, so does the concern of major depressive disorder. Despite the need to forcefully recognize and address depression among this age group, efforts have been docile and passive; many elderly individuals continue to go undiagnosed. With the increase of Latino population within the past and upcoming decades and with studies showing that elderly Latinos appear to live longer than non-Latinos, it is critical that differences in treatment interventions be explored. This study aimed to explore the use of familismo (intense importance and attachment the Latino culture places on nuclear and …

Help-Seeking Behaviors Among Filipino Americans: Understanding Enculturation, Depression, And Anxiety, Kristoffer John Almazan Rouse

Walden Dissertations and Doctoral Studies

Filipino Americans have some of the highest levels of psychological distress among all Asian Americans. However, underrepresentation in psychological studies and a unique set of cultural values and norms contribute to the lack of literature on the sources of this distress among Filipino Americans. The purpose of this quantitative study was to examine how aspects of cultural assimilation and norms of Filipino culture affect willingness of Filipino Americans to seek mental health services. Several factors, enculturation, anxiety, and depression, among Filipino Americans were examined to predict influence on help-seeking behaviors. A sample of 120 Filipino Americans living in the Pacific …

College Students And Their Decisions To Disclose Disabilities, Matthew A. Christian

Walden Dissertations and Doctoral Studies

Legislation in the United States mandates support services to assist students with disabilities in postsecondary settings, and research literature includes legislation and case law dealing with access rights to higher education and studies in areas of transitioning to postsecondary settings, including perceptions of support services and barriers to attainment. Yet, the processes that require students to divulge increasingly personal information related to their disabilities can discourage the students who need services. There is a gap in research and practice concerning the factors leading these students to decide to disclose; therefore, the purpose of this narrative inquiry was to explore the …

Promoting The Recognition Of Depression In The Geriatric Population, Rose L. Hodge

Walden Dissertations and Doctoral Studies

Depression is a chronic condition that has both physical and mental consequences, complicating the elderly’s health status and interfering with daily functioning. Depression is not a normal part of aging and the elderly frequently seek mental health care in outpatient clinical settings where there is need for effective screening and prompt recognition leading to decreased morbidity and mortality. It is critical for psychiatric care settings to provide the most effective screening tools for recognizing depression as quickly as possible. This Doctoral Nursing Project quality improvement (QI) evaluation project resulted from observation of lack of a tool for recognizing depression in …

Neighborhood Factors, Depression, And Body Mass Index Among Patients With Lupus In Georgia, Aisha L. Hill

Walden Dissertations and Doctoral Studies

Elevated BMI (overweight and obesity) is a common health-related issue and affects more than half of the lupus population. Weight issues lead to additional health-related issues, such as heart disease and disabilities in the lupus population. To address the shortage of research focusing on this specific issue in the lupus population, one approach is a novel outlook on how neighborhood factors have the capability of determining or altering behaviors, such as physical activity, healthy eating, and healthy social relationships. Another variable to consider is depression and its capability of altering interactions, relationships, self-esteem, or even the inflammatory state of the …

Ketamine Pre-Exposure Does Not Influence Later-Life Responses To Reward-Related Stimuli In Female C57bl/6 Mice, Israel Garcia

Open Access Theses & Dissertations

Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent and adult female subjects, alters reward-related behavior later in life. In recent years, the anesthetic ketamine (KET), now used as a fast-acting antidepressant, has shown promising therapeutic efficacy for the management of depression. However, the potential long-term behavioral consequences of KET exposure across development have not been thoroughly assessed. Thus, to address this issue, we examined if KET exposure, during adolescence or early adulthood, results in enduring alterations in responsivity to the rewarding properties of sucrose and cocaine later in life. Specifically, female C57BL/6 mice were randomly assigned to …

Pediatric Providers' Perceptions Of Their Role In Early Detection Of Postpartum Depression, Laura Aime De La Pena

Dissertations

The birth of a child is usually a happy occasion in a woman's life. It is also often a time of overwhelming anxiety, stress and hormonal changes. Postpartum depression (PPD) could occur during the first year of childbirth in approximately 10-20% of mothers (Waldrop, Ledford, Perry, & Beeber, 2017). PPD is the most common maternal health problem within the first year after childbirth (the American College of Obstetricians and Gynecologists, 2018). Recognition of mothers who are at risk for PPD allows health professionals to initiate care that can prevent further problems for the mother, infant, and the rest of their …

Population Demographics: Predictors Of The Relationship Between Alcohol Use Disorder And Major Depression, Mei Grace Behrendt

Honors Program: Senior Projects (Public)

This thesis examines both biological and social explanations of alcohol use disorder (AUD) and major depression (MD) through a thorough review of current literature. Using multiple logistic regression analyses exploring the sociodemographic and alcohol use factors that contribute to reporting of major depression symptoms with data from the 2017 National Survey on Drug Use and Health, this thesis demonstrates how there are health disparities that exist among different demographic populations. Specifically, certain demographic characteristics such as racial or ethnic identity, gender, and socioeconomic status may contribute to increased risk of developing and reporting episodes of lifetime and past year major …

Antidepressant Exposure In Pregnancy And Child Sensorimotor And Visuospatial Development, Megan Galbally, Stuart J. Watson, Olav Spigset, Philip Boyce, Tim F. Oberlander, Andrew J. Lewis

Medical Papers and Journal Articles

Motor development underlies many aspects of education and learning. There has been uncertainty about the impact of exposure of antidepressant medication in pregnancy on child motor outcomes. This paper examines whether exposure to antidepressants in utero increases the risk of poorer motor development in two areas: sensorimotor and visuospatial processing. Data were obtained from 195 women and children across 3 groups: women with untreated depression in pregnancy, women treated with antidepressants and control women. Data were collected across pregnancy, postpartum and until 4 years for mother and child. Maternal depression was established at baseline with the Structured Clinical Interview for …

Fatherhood Too Soon. Anxiety, Depression And Quality Of Life In Fathers Of Preterm And Term Babies: A Longitudinal Study, Ingrid Beatrice Petersen, Julie Anne Quinlivan

IHR Papers and Journal Articles

Introduction: Fathers are increasingly recognized as playing a critical role in the family unit and emotional development of children. The birth of a preterm baby can be confronting, yet there is limited research that explores how preterm birth might impact on father’s emotional wellbeing and quality of life. The aim of the study was to monitor quality of life and psychological wellbeing in a group of fathers to explore if a preterm birth altered outcomes in these two domains.

Methods: Institutional ethics committee approval was obtained. Australian men (N = 1000) were recruited in the antenatal period via their …

Clinically Significant Depressive Symptoms Are Prevalent In People With Extremely Short Prognoses - A Systematic Review, Wei Lee, Marley Pulbrook, Caitlin Sheehan, Slavica Kochovska, Sungwon Chang, Annmarie Hosie, Elizabeth Lobb, Deborah Parker, Brian Draper, Meera R. Agar, David Currow

Nursing Papers and Journal Articles

Context: Currently, systematic evidence of prevalence of clinically significant depressive symptoms in people with extremely short prognoses is not available to inform its global burden, assessment, and management.

Objectives: To determine the prevalence of clinically significant depressive symptoms in people with advanced life-limiting illnesses and extremely short prognoses (range of days to weeks).

Methods: A systematic review and meta-analysis (random effects model) were performed (PROSPERO: CRD42019125119). MEDLINE, Embase, PsycINFO, CINAHL, and CareSearch were searched for studies (1994-2019). Data were screened for prevalence of clinically significant depressive symptoms (assessed using validated depression-specific screening tools or diagnostic criteria) of adults with advanced …

Molecular And Behavioral Mechanisms Mediated Paclitaxel-Induced Changes In Affect-Like Behavior In Mice, Julia Meade

Theses and Dissertations

Paclitaxel and oxaliplatin are two chemotherapeutics that cause acute neurotoxicity and chemotherapy-induce peripheral neuropathy (CIPN) in 70-90% of cancer patients. Chemotherapy-induced sensory changes are correlated with depression and anxiety. We characterized the effects of these drugs on sensation and various mood-related behaviors in mice, to determine if changes in sensation are associated with depression-like behavior, to explore putative mechanisms of chemotherapy-induced depression-like behavior (Aim 1), and to develop a mouse model of chemotherapy-induced operant responding deficit (Aim 2). In Aim 1, we observed that a cumulative dose of 32 mg/kg paclitaxel induced mechanical hypersensitivity and transiently reduced preference for sucrose …

Integration Of Multi-Omic Platforms To Understand The Regulation Of Genes In Human Disease, Eva Lancaster

Theses and Dissertations

Epigenetic mechanisms have been hypothesized to modify gene expression (GE) in response to both genetic variation and environmental exposures, ultimately contributing to the development of complex traits. Epigenome-wide association studies (EWAS) aim to test the theory that marks of DNA methylation (DNAm) have downstream consequences that result in the development of complex diseases. Although these methods have been successful in identifying DNAm patterns in complex traits, specific molecular mechanisms involved in the etiology of complex diseases remain unidentified. This knowledge gap does not originate from a lack of DNAm-trait associations, but rather stems from study design issues that affect the …

The Association Between Temperament Features And Childhood Traumas In Patients With Juvenile Myoclonic Epilepsy, Ali̇şan Burak Yaşar, Ceyhun Sayman, Serap Erdoğan Taycan, Yilmaz Çeti̇nkaya, Anil Gündüz, Hülya Ti̇reli̇

Turkish Journal of Medical Sciences

Background/aim: Epilepsy is a common chronic neurological problem that impairs daily activities, functionality, and quality of life. Childhood traumas (CTs) are known to be critical factors in the onset or development of many psychiatric and medical disorders. They also play a critical role in the development of temperament and personality. This study aimed to investigate the association between CTs and common temperament patterns and features seen in epilepsy patients. Materials and methods: The study included 38 patients who were diagnosed with juvenile myoclonic epilepsy (JME) and volunteered to participate in the study. In addition to the sociodemographic form and questions …

Is Helping Really Helping? Health-Related Quality Of Life After Tbi Predicting Caregiver Depression Longitudinally In Latin America, Chimdindu Ohayagha, Paul B. Perrin, Mickeal Pugh Jr., Yaneth Rodriguez, Silvia Olivera, Maria Cristina Quijano, Juan Carlos Arango-Lasprilla

Graduate Research Posters

Objective: Studies have shown that functional and psychosocial sequelae of traumatic brain injury (TBI) predict emotional well-being of caregivers (Harris, 2000). Previous research examining the mental health of caregivers and the health-related quality of life (HRQoL) of people with TBI have primarily been in the US (Sander, 2012). Very little research has been conducted to uncover the unique relationships between HRQoL of people with TBI and caregiver mental health longitudinally, or in low-middle income Latin American countries. The aim of this study was to evaluate how HRQoL after TBI predict caregiver depression longitudinally in two countries and three data collection …

Utilizing Act Daily As A Self-Guided App For Clients Waiting For Services At A College Counseling Center: A Pilot Study, Jack Haegar, Carter H. Davis, Michael E. Levin

Psychology Faculty Publications

Objective: Considering increasing demands for mental health services at college counseling centers (CCCs), there is a need for cost-effective solutions that avoid depleting stressed CCC resources. This study examined if ACT Daily, a mobile application based on acceptance and commitment therapy (ACT), could serve as an effective self-guided intervention.

Participants: 11 individuals on a CCC waitlist suffering from anxiety/depression participated in the study over 2 weeks.

Methods: This study implemented a pre-post, open trial design of ACT Daily. Assessments were completed at baseline and 2-week post assessment.

Results: Results indicated that ACT Daily was acceptable and that participants improved on …

Grieving The Eternal Present: The Pressures Of Being A Person (With Words), Rowen Light-Wills

Scripps Senior Theses

I started this poetry project from the jumping off point of psychoanalyst Donald Winnicott's most well known theory; that of the "good enough" mother. This appealed to me because like Freud's, Lacan's, and other psychoanalysts’ work, it centers the infant and attempts to understand the developing psyche. In combination with Melanie Klein’s theories, this thesis aims to pinpoint specific anxieties that transcend childhood and feel applicable to the rest of the relationships a person develops in their life. Did they experience nurturing and detach from their primary caregiver at a developmentally healthy time? Or did they lack some relationship between …

Depression In Young Adult Women Following Childhood Maltreatment: The Role Of Attitudes And Perceptions About Social Support, Thomas Dodson

Electronic Theses and Dissertations Archive

Introduction: A history of childhood maltreatment has been related to mental health concerns inadulthood, with depression showing the largest amount of empirical support. Perceptions of social support have been shown to have a protective effect (buffer against mental health symptoms particularly for survivors of more severe maltreatment) and a promotive effect (direct positive effect on mental health symptoms regardless of the severity of child maltreatment) with mental health concerns. Research has shown more consistent support for the promotive effect of social support on mental health outcomes in adults who have a history of childhood maltreatment. The protective effect of social …

What Happens When Youth Talk About Their Problems? Co-Rumination As A Mechanism Of Stress Generation, Jaclyn T. Aldrich

Clinical Psychology Dissertations

During adolescence, rates of depression increase significantly, necessitating understanding of interpersonal and intrapersonal factors that contribute to the occurrence of depressive symptoms. Prominent theories of depression, such as stress generation theory, suggest that depressed individuals experience more interpersonal stress that is dependent on their own actions or behavior. The current study sought to examine the role of co-rumination in the generation of stress and development of depression over the course of a year. Participants were 150 adolescents (48.7% female, 77.5% Caucasian) ages 11 to 14 years old (M = 13.03, SD = 0.93). Three models assessed the directional relationship …

Educating Nurses About Poststroke Depression And Using The Phq-2/9, Mary Mcmullen

Walden Dissertations and Doctoral Studies

Stroke has affected more than 7 million people and up to 33% of those patients reporting depression. The lack of screening for depression for patients post stroke can delay treatment for depression and hinder or lengthen recovery. The purpose of this project was to develop a nursing staff education program on using the Patient Health Questionnaire (PHQ) tools (PHQ-2 and PHQ-9) at the bedside to detect signs and symptoms of depression and identify nurse-driven interventions. Using the Johns Hopkins nursing evidence-based practice model and Orem's self-care model for guidance, an interdisciplinary team was assembled to collaborate on the development. A …

Depression And Awareness Of Mental Health Resources Among Minority And Non-Minority College Students, Henry David Browne

Walden Dissertations and Doctoral Studies

Minority college students experience higher levels of psychological stress and depression, and lower utilization of mental health resources (MHR) compared to the general student population. The purpose of this quantitative study was to examine the association between self-reported depressive symptoms and awareness of mental health services among college undergraduate minority and non-minority students, controlling for sex, interest in MHR information, and history of mental illness. The self-determination theory guided the study. The study utilized a cross-sectional research design using secondary survey data from the National College Health Assessment (NCHA). The NCHA dataset included 354,262 respondents from 52 self-selected U.S. colleges …

The Role Of Self-Mutilation Behaviors Among Adolescents Who Are Depressed, Patricia Wilkins

Walden Dissertations and Doctoral Studies

Adolescents who are depressed may self-injure themselves. Common methods for non-suicidal self-injury are cutting and burning the skin of one’s own body. Multiple confounding factors of age, gender, race and socio-economic status could lead one to engage in intentional or unintentional self-mutilation acts. The current body of literature on adolescent mental health demonstrates limited understanding of how racial and ethnic identity factors contributes to depression, self-injurious behavior, and suicide. This quantitative study determined if there was a relationship between depression and prevalence of adolescent self-mutilation. The social ecological theory was used to study the intersection of social determinants of depression …

Acknowledging And Addressing Adolescent Depression, Johnsie Burke Hughes

Walden Dissertations and Doctoral Studies

A family practice was found to inconsistently screen adolescents for depression even with the necessary Patient Health Questionnaire (PHQ) screening tools being readily available in their electronic medical record. The development of a practice guideline that offers a systematic approach to screening using the PHQ2 and the PHQ9 will potentially result in an increased guidance and provider willingness to screen for adolescent depression in the family practice setting. The purpose of this DNP project was to determine if an algorithmic practice guideline would increase provider willingness to assess for adolescent depression and identify any barriers to the use of the …

Comorbidity In Context: Identifying Patterns Of Depressive And Anxiety Symptoms In African American Early Adolescents, Kathryn Behrhorst

Theses and Dissertations

Depression and anxiety during adolescence includes symptoms of irritability, sleeplessness, feelings of guilt or worthlessness, worry, avoidance, and/or restlessness. Anxiety and depressive symptoms are often comorbid and are associated with impairments across academic, social, and emotional areas of functioning. No studies to date have examined patterns of depressive and anxiety symptoms together for African American adolescents using person-centered analyses. The current study examined patterns of symptoms and domains of anxiety and depression during early adolescence using latent profile analyses (LPA). A sample of 196 African American early adolescents in grades six through eight (M_age = 12.6; 50% female) were …

The Correlation Between Maternal Postpartum Depression And Child Psychopathology, T'Keyah I. Vaughan

Theses and Dissertations

Background: Postpartum depression (PPD) is a phenomenon that affects nearly 10-15% of pregnancies in the US. It is characterized by depressed mood or anhedonia and lasting for more than 2 weeks. PPD changes how moms interact with family members and child-rearing behavior. Depression is a phenomenon that is also known to affect the psychopathology of children. However, the specifics of how postpartum depression impacts children remains controversial. Many studies do not control for major depressive disorder which makes it difficult to disentangle the impact depression has within the first year of life. Furthermore, other PPD risk factors may be confounding …