Digital Commons Network^™

Screening For Depression Among A Sample Of Us College Students Who Engage In Recreational Prescription Opioid Misuse, Robert E. Davis, Martha A. Bass, M. Allison Wade, Vinayak K. Nahar

Faculty and Student Publications

© 2020 The Author(s). Background: Among student populations, literature has identified associations between prescription opioid misuse and symptoms of depression such as hopelessness, sadness, and emotional pain. Thus far, existing literature has yet to investigate associations between prescription opioid misuse and depression using validated screening instruments for depression when exploring such associations. The purpose of this study was to utilize a validated screening tool to explore quantifiable presence of depression among college students who engage in recreational prescription opioid misuse (RPOM). Additionally, gender differences in depression and co-occurring substance use are examined. Methods: Students (n = 104) of a large …

Analysis Of Tech-Based And Telemental Health Approaches Within The Adolescent And Young Adult Populations Of Rural America, Audrey K. Smeenk

Physician Assistant Scholarly Project Posters

The incidences of depression and anxiety among adolescent and young adult populations are intensifying, and resources remain limited for the management of these diseases within rural America.

• Evaluation on different interventions was completed to assess ease of access, efficacy, and patient adherence with the hope to decrease incidence of disease and increase availability of resources to rural areas.

• Based on the current completed research, there is a predominance of evidence that has shown moderate statistical data and promising outcomes from tech-based mobile applications and telemental health. Statistical evidence supports that technological based interventions are a potential treatment option …

Quality Of Life Of Adults With Chronic Spinal Cord Injury In Mainland China: A Cross-Sectional Study, Fengshui Chang, Haixia Xie, Qi Zhang, Mei Sun, Yuhui Yang, Gang Chen, Huifang Wang, Chengyue Li, Jun Lu

Community & Environmental Health Faculty Publications

Objective: To evaluate the quality of life of patients with chronic spinal cord injury in mainland China.

Design: Cross-sectional study. Subjects: A total of 247 adults ≥ 1 year post-SCI in mainland China.

Methods: The World Health Organization (WHO) Quality of Life Scale Brief Version (WHOQOL-BREF) and the add-on modules on disability-related QoL (WHOQOL-DIS) were used to assess quality of life. Anxiety/depression was measured using the Zung Self-Rating Anxiety/Depression Scale. Quality of life was compared with that of reference populations from China, Korea, the international field trial (23 countries). Multivariate linear regression was conducted to determine the factors that might …

Effectiveness Of Physical Exercise In Treating Depression Versus Conventional Treatments: A Systematic Review, Julianne Ferrie, Coleby Charlier

Student Research Poster Presentations 2020

Purpose: This systematic review was done to compare the effects of physical exercise on depression versus the standard treatments most patients who are diagnosed with depression receive, which includes antidepressant medication and cognitive behavioral therapy. There is not currently a collective source that summarizes the various studies on this topic within the physical therapy world. Our article compiles relevant information that supports physical exercise as an alternative treatment for individuals who have been diagnosed with depression. We sampled randomized control studies and prospective cohort studies for data and results, and systematic reviews for supporting information. Our research will be a …

Treatment Option Decision Making For Low-Grade Prostate Cancer, Janene Witherite

Physician Assistant Scholarly Project Posters

Prostate cancer (PCa) is the second most common cancer, among men, in the United States.

 Low-grade PCa is defined by; lack of metastasis outside the prostate (M0), no lymph node involvement (N0), tumor staging up to T2a, a PSA of less than 10 ng/ml, a Gleason score of less than 6, and no more than two of the 10-12 tissue samples (each composed of less than 50% cancer cells) of the 10-12 samples taken.

 Four treatment options exist for low-grade PCa patients: active surveillance (AS), external beam radiotherapy (EBRT), brachytherapy, and radical prostatectomy (RP), all of which cause …

Support For Screening And Intervening On Adolescent Depression: Provider-Reported Training Outcomes, Leah Rose Lalonde

Master's Theses and Doctoral Dissertations

Given the potential consequences of untreated adolescent depression and the prevalence of untreated mental health among adolescents, the American Academy of Pediatrics has strongly recommended active support and monitoring of depressive symptoms in pediatric primary care. Primary care providers (PCPs), however, do not have sufficient training to provide this level of care, contributing to low rates of identification and management of depression. The purpose of the current pilot study was to evaluate a training aimed at supporting providers in the management of adolescent depression. Results demonstrated that providers were accepting of the training and that provider knowledge of depression management …

Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden

Brain and Mind Institute Researchers' Publications

© 2020 The Author(s) Self-referential processing (i.e., self-schemas that guide processing of self-descriptive information) emerges early in youth, with deeper encoding of negative self-descriptors and/or shallower encoding of positive self-descriptors causally linked to depression. However, the relationship between depressogenic self-schemas and brain structure is unclear. We investigated associations between self-schemas and regional grey matter volume (GMV) in 84 never-depressed preadolescents oversampled for depression risk based on maternal depression history. Self-schemas were assessed using a Self-Referent Encoding Task (SRET) and regional GMV was indexed via voxel-based morphometry analysis of structural magnetic resonance imaging data. Youths’ positive self-schemas were associated with greater …

Orbitofrontal Cortex Grey Matter Volume Is Related To Children's Depressive Symptoms, Matthew R.J. Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R. Daoust, Marc F. Joanisse, Deanna M. Barch, Elizabeth P. Hayden

Brain and Mind Institute Researchers' Publications

© 2020 The Author(s) Adults with a history of depression show distinct patterns of grey matter volume (GMV) in frontal cortical (e.g., prefrontal cortex, orbitofrontal cortex) and limbic (e.g., anterior cingulate, amygdala, hippocampus, dorsal striatum) structures, regions relevant to the processing and regulation of reward, which is impaired in the context of depression. However, it is unclear whether these GMV associations with depression precede depressive disorder onset or whether GMV is related to early emerging symptoms or familial depression. To address these questions, we used voxel-based morphometry (VBM) to examine GMV in 85 community-dwelling children (M = 11.12 years, SD …

How 6-12th Grade Staff Support Students With Depression: A Pilot Study To Develop Measures Of Implicit Associations, Explicit Attitudes And Helping Behavior, Paul M. Thompson

Electronic Theses and Dissertations

Students with emotional disabilities are disproportionately suspended and expelled in K-12 schools. Attribution theory suggests individuals are less likely to provide assistance to others if they believe the individuals are responsible for their own difficulties. To test attribution theory, this study created new measures of explicit attitudes and implicit associations of licensed 6-12th grade staff regarding students with depression as well as a helping behavior measure of staff toward students with depression. The survey was distributed within a single school district in the western United States. A majority of the sample (N = 52) held a mental health license (60%), …

Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden

Brain and Mind Institute Researchers' Publications

© 2020 The Author(s) Self-referential processing (i.e., self-schemas that guide processing of self-descriptive information) emerges early in youth, with deeper encoding of negative self-descriptors and/or shallower encoding of positive self-descriptors causally linked to depression. However, the relationship between depressogenic self-schemas and brain structure is unclear. We investigated associations between self-schemas and regional grey matter volume (GMV) in 84 never-depressed preadolescents oversampled for depression risk based on maternal depression history. Self-schemas were assessed using a Self-Referent Encoding Task (SRET) and regional GMV was indexed via voxel-based morphometry analysis of structural magnetic resonance imaging data. Youths’ positive self-schemas were associated with greater …

Orbitofrontal Cortex Grey Matter Volume Is Related To Children's Depressive Symptoms, Matthew R.J. Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R. Daoust, Marc F. Joanisse, Deanna M. Barch, Elizabeth P. Hayden

Brain and Mind Institute Researchers' Publications

© 2020 The Author(s) Adults with a history of depression show distinct patterns of grey matter volume (GMV) in frontal cortical (e.g., prefrontal cortex, orbitofrontal cortex) and limbic (e.g., anterior cingulate, amygdala, hippocampus, dorsal striatum) structures, regions relevant to the processing and regulation of reward, which is impaired in the context of depression. However, it is unclear whether these GMV associations with depression precede depressive disorder onset or whether GMV is related to early emerging symptoms or familial depression. To address these questions, we used voxel-based morphometry (VBM) to examine GMV in 85 community-dwelling children (M = 11.12 years, SD …

Caregiver Support And The Mental Health Of Transgender And Gender Expansive Youth: Race-Specific Effects In A Clinic-Based Sample, Whitney Morgan Menary

Public Health Theses

Parental and caregiver support has been shown to be a protective factor against poor mental health in transgender and gender expansive (TGE) youth. However, little is known about how race and ethnicity might affect this relationship. This study extends the literature by examining whether the associations between parental support and mental health outcomes are moderated by race. A clinic-based sample of 81 TGE youth (mean age = 15.31, SD = 1.61) completed assessments of their anxiety and depression symptoms. Caregiver support scores were gathered from youth and the caregivers themselves. Results show that TGE youth of color have decreased odds …

Behavioral Symptoms, Inflammation And Cortisol: Relationship To Cardiac Health And Quality Of Life In Cardiac Rehabilitation Patients, Deborah Anne Sindewald

Dissertations

Background: The experience of a cardiac event is associated with psychological stress, which is often accompanied by depressive mood, fatigue and sleep disturbance (i.e., psycho-behavioral symptoms). To assist in recovery, cardiac patients can participate in a structured rehabilitation program, which provides monitored exercise and health education. There is limited knowledge, however, as to the extent to which cardiac rehabilitation reduces psycho-behavioral symptoms; nor is there knowledge of the association of these symptoms with stress-related biological mediators. Cortisol and inflammatory mediators (e.g., interleukin 6; IL-6) contribute to cardiovascular disease, and are also associated with greater stress perception, depressive mood, fatigue, and …

Multiple Sclerosis With Depression, Dr. Siri Gangadkar, Dr. Megha Tandure, Dr. Kishor M

Digital Journal of Clinical Medicine

No abstract provided.

Psilocybin-Assisted Psychotherapy: Treating Depression And Anxiety With Mushrooms, Sofia Beck

Physician Assistant Studies | Student Authored Articles

Depression and anxiety are debilitating mental health conditions that affect a large portion of the United States. Current pharmacological treatments for these disorders require daily administration, are associated with a number of side effects, and can be ineffective for some. Emerging evidence in novel treatment options may necessitate a shift toward how we treat these psychiatric disorders.

Studies involving the psychedelic serotonin agonist, psilocybin, are currently experiencing a resurgence as an alternative for patients who are unresponsive to traditional treatments. Clinical trials using psilocybin in combination with psychotherapy have demonstrated sustained reductions in depression and/or anxiety symptoms. When used in …

Impairment Or Underestimation? Negative Illusory Bias In Depressive Symptoms And Theory Of Mind, Jaclyn Boyer

Undergraduate Honors Thesis Collection

Theory of Mind (ToM) is the social-cognitive skill of attributing beliefs, feelings, and intentions to others in order to predict their future behavior. Past research on ToM and depression is quite ambiguous; some studies have found significant impairment of ToM performance in depressed individuals, while others have found that depressed individuals perform better than those without depression. The purpose of the study was to clarify this ambiguity by considering the phenomenon of negative illusory bias (NIB) as a potential mediating variable. NIB refers to the tendency of competent individuals to underestimate their abilities. Therefore, along with measures of ToM and …

Impact Of Status-Based Rejection Sensitivity On Depression And Anxiety Symptoms In Gay Men, J. Simowicz, Jedidiah Siev, P. M. Brochu

Psychology Faculty Works

Status-based rejection sensitivity refers to the anxious expectation and tendency to perceive rejection in ambiguous social scenarios based on one’s minority identification. This study evaluates the implications of sensitivity to rejection based on sexual orientation identity on negative mental health outcomes. Current minority stress models include rejection sensitivity as a factor that may contribute to adverse negative psychosocial outcomes in LGBT persons. This study evaluates the role of rejection sensitivity alongside demographically relevant predictors such as age, race, education, and level of sexuality disclosure in predicting the presence of significant depression and anxiety scores among a sample of gay men. …

Immediate Effects Of Yoga On Mindfulness, Self-Criticism, Self-Compassion And Depressed Mood, Blaire Cain

West Chester University Master’s Theses

This study examines changes in self-compassion, self-criticism, mindfulness and depressed mood following a single yoga session. This study sets itself apart from already completed research by examining the effects of one single yoga session, as opposed to 4-, 6-, or up to 12 weeks of yoga intervention. Other research exists in this growing knowledge base, see Woodyard (2011) for a review, and the research has deemed positive results over time. This project was designed to determine if any change can be measured after just one yoga class, supporting the idea that yoga may be utilized as a singular or complementary …

School-Based Racial Microaggressions And Symptoms Of Depression Among Native American Young Adults, Olivia Grace Bridges Holter

Graduate Student Theses, Dissertations, & Professional Papers

Native Americans continue to experience higher than average prevalence rates of mental health disorders, including depression. Current research on the risk factors for the development of mental health disorders among Native Americans suggests that the experience of prejudice is strongly correlated with the diagnosis of mental health disorders. Despite this knowledge, there is a current gap in the literature examining relationship between the experience of prejudice in schools and the development of mental health disorders for Native Americans. Given this dearth of research as well the importance of understanding the mental health needs of Native Americans, this research study examined …

Preliminary Investigation Of An Aphasia-Friendly Version Of The Patient Health Questionnaire – 8 (Phq-8) Compared To Other Patient And Proxy Reported Outcome Measures Of Depression, Kaylee Marie Walter

Graduate Student Theses, Dissertations, & Professional Papers

Persons with aphasia (PWA) experience post-stroke depression more frequently than stroke survivors who do not have aphasia. Currently, no patient reported outcome measures that screen for depression have been created specifically for PWA or modified to be aphasia friendly for PWA. The purpose of this preliminary study is to modify the Patient Health Questionnaire- 8 (PHQ-8) to an aphasia friendly format and to assess the feasibility of administering the modified assessment compared to other patient-reported and proxy-reported outcome measures used to screen depression. This retrospective analysis examined pre- and post-treatment outcome measures of depression for seven stroke-survivors with aphasia. The …

College Students' Social Media Uses And Affective Correlates, Jennifer L. Lippold

Graduate Student Theses, Dissertations, & Professional Papers

Given the high prevalence of mental health conditions such as depression and anxiety among college students, research on social media use, a salient feature of the modern college experience, is increasingly warranted. While research documents a link between negative psychological symptomology and social media use, few studies have examined what specific patterns of use may be more or less harmful than others. Therefore, the present study investigated whether specific types of social media use (socially oriented uses, information seeking uses, and entertainment uses) are more or less strongly associated with affective variables (depression, anxiety, positive affect, and negative affect). Utilizing …

Sleep, Experiential Avoidance, And Mental Health Symptoms, Anthony Reffi

Graduate Research Theses & Dissertations

The explanatory mechanisms by which sleep disturbances promote psychopathology are not well understood. Given that poor sleep promotes a broad range of negative emotions the next day, sleep disturbances may increase the tendency to identify inner experiences as aversive, thereby promoting experiential avoidance (EA). Though temporarily effective, the frequent and rigid use of EA has been shown to worsen mental health. Therefore, using a seven-day ecological momentary assessment design, this study investigated momentary EA as a mechanism linking subjective sleep quality and quantity with subsequent anxiety and depressive symptoms. Undergraduate participants (N = 86, Mage = 19.72) first completed an …

The Gut-Brain Axis: Treating Depression Through Microbiome Alterations, Alexandria Bachman-Williams

Physician Assistant Scholarly Project Posters

• The purpose of this study is to explore the role of gut microbiome alterations in the treatment of anxiety and depression. • There are multiple pathological pathways that lead to the development of anxiety and depression. • Research shows a link between pathologic bacteria and low grade inflammation. This causes a disruption of neurotransmitters that are current targets of pharmacological treatment of depression and anxiety. • Transfer of “pathogenic” bacteria caused increased symptoms of anxiety and depression. • Treatment with probiotics and “protective” bacteria showed decreased BDI scores and improved symptoms. • Studies were small but show need for …

Use Of Marijuana In Those With Anxiety And Depression, Heather Flaa

Physician Assistant Scholarly Project Posters

The purpose of this research and literature review was to compare the use of marijuana to SSRIs in reducing anxiety and depression symptoms.

• This literature review searched databases Cochrane, PubMed, Clinical Key, PsycINFO, and DynaMed Plus from the year 1990 and on. Keywords: cannabis, marijuana, anxiety, generalized anxiety disorder, depression, and selective serotonin reuptake inhibitors.

• Many meta-analyses show SSRIs continue to be first line treatment in those with anxiety and depression in reducing symptoms.

• Patients with marijuana use showed an increased odds ratio of developing anxiety and depression or increasing symptoms in several studies.

• No studies …

Image Acquisition And Quality Assurance In The Boston Adolescent Neuroimaging Of Depression And Anxiety Study, Viviana Siless, N. A. Hubbard, Robert Jones, Jonathan Wang, Nicole Lo, Clemens C. C. Bauer, Mathias Goncalves, Isabelle Frosch, Daniel Norton, Genesis Vergara, Kristina Conroy, Flavia Vaz De Souza, Isabelle M. Rosso, Aleena Hay Wickham, Elizabeth Ann Cosby, Megan Pinaire, Dina Hirshfeld-Becker, Diego A. Pizzagalli, Aude Henin, Stefan G. Hofmann, Randy P. Auerbach, Satrajit Ghosh, John Gabrieli, Susan Whitfield-Gabrieli, Anastasia Yendiki

Department of Psychology: Faculty Publications

The Connectomes Related to Human Diseases (CRHD) initiative was developed with the Human Connectome Project (HCP) to provide high-resolution, open-access, multi-modal MRI data to better understand the neural correlates of human disease. Here, we present an introduction to a CRHD project, the Boston Adolescent Neuroimaging of Depression and Anxiety (BANDA) study, which is collecting multimodal neuroimaging, clinical, and neuropsychological data from 225 adolescents (ages 14–17), 150 of whom are expected to have a diagnosis of depression and/or anxiety. Our transdiagnostic recruitment approach samples the full spectrum of depressed/anxious symptoms and their comorbidity, consistent with NIMH Research Domain Criteria (RDoC). We …

An Integrated Relational Framework Of Depressed Mood And Anhedonia During Pregnancy, Rebecca L. Brock, Molly Franz, Erin L. Ramsdell

Department of Psychology: Faculty Publications

Objective: The aim of the present study was to test a unified framework that integrates several theories into a cohesive model to explain the interplay between neuroticism and intimate relationship quality as risk factors for prenatal depression.

Background: There is a notable spike in risk for depression during pregnancy, and the processes unfolding in the interparental relationship during this important time in the family life cycle might serve to mitigate or enhance this risk. Yet there is a need for theory-driven research integrating multiple conceptual frameworks to explicate the role of intimate relationship quality in depression.

Method: In a sample …

Diabetes Locus Of Control And Depression In Older Adults With Type 1 And Type 2 Diabetes: The Study Of Longevity In Diabetes, Jahvona Pretty

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Abstract:

Objective: To determine if diabetes locus of control (dLOC) is associated with depression in older adults with type 1 and type 2 diabetes and whether this association differs by diabetes type.

Methods: Data for the current study were obtained from The Study of Longevity in Diabetes (SOLID), a prospective cohort study of aging, and diabetes. SOLID participants aged 60 and older with type 1 diabetes (T1D), type 2 diabetes (T2D), and without diabetes were recruited from members of Kaiser Permanente Northern California (KPNC). For the current study, we excluded all of the participants without diabetes since the primary exposure, …

Sexual Risk: Contributing Factors To High-Risk Sexual Behaviors In A Transgender/Gender Non-Conforming Population, Jo Crowl

Doctor of Psychology (PsyD)

There are a variety of factors associated with the frequency of risky sexual behaviors. Whereas spirituality is a protective factor for certain populations, depression is correlated with higher rates of sexual risk behaviors. Until now, the relationship between access to healthcare and these risky sexual behaviors has not been studied. This study sought to determine the impact of spirituality, depression, and access to healthcare with risky sexual behaviors for individuals who identify as transgender/gender non-conforming (TGNC). Data was collected from TGNC adults over the age of 18 using an online survey method. This study did not find significant relationships involving …

Effectiveness Of Reminders Via Messaging Apps In Improving Clinic Attendance And Medication Compliance Among Patients With Depression, Pei Teeng Low

Student Works (2020-2029)

Background: Non-attendance at clinic appointments and medication non-compliance are both common issues within psychiatric settings, with forgetting being specified as one the most common reasons. This phenomenon may be worse for patients who are suffering from depression. Thus, the use of regular reminders in some format for such patients could be potentially very beneficial. With cognizance of the exponential growth of smartphone usage and social media awareness during the past decade, a messaging apps maybe a potentially efficient and cost-effective method of sending such reminders in a healthcare setting. Objective: To determine the potential effectiveness of sending reminders via messaging …

Putting Adversity In Perspective: Purpose In Life Moderates The Link Between Childhood Emotional Abuse And Neglect And Adulthood Depressive Symptoms, Andree Hartanto, Jose C. Yong, Sean T. H. Lee, Wee Qin Ng, Eddie M. W. Tong

Research Collection School of Social Sciences

Background: Childhood emotional abuse and neglect is linked with a host of adverse outcomes later in life, including depression. However, potential psychological resources that may mitigate the adverse outcomes of childhood emotional abuse and neglect are not well-understood. Aims: Drawing from the insight that having a sense of purpose can help individuals deal with setbacks and difficulties better, we propose that purpose in life can also help sufferers of childhood maltreatment cope more effectively and reduce the onset of depressive symptoms. Methods: Participants were drawn from two large, nationally representative studies comprising a total of 3664 respondents. Purpose in life, …