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Risk Of Maternal And Fetal Outcomes Associated With Covid-19 Variants Of Concern: A Sequential Prospective Meta-Analysis, Fouzia Farooq Apr 2023

Risk Of Maternal And Fetal Outcomes Associated With Covid-19 Variants Of Concern: A Sequential Prospective Meta-Analysis, Fouzia Farooq

GW Research Showcase 2021-2026

No abstract provided.


Covid-19 Psychosis In An Adolescent, Danielle Healey, Rishi Gautam Apr 2023

Covid-19 Psychosis In An Adolescent, Danielle Healey, Rishi Gautam

GW Research Showcase 2021-2026

No abstract provided.


The Future Of People Becoming The Church: Multiplying Disciples, Leaders, And Campuses In A Post-Christian, De-Churched, And Unchurched Region Of The United States, Wesley D. Davis Apr 2023

The Future Of People Becoming The Church: Multiplying Disciples, Leaders, And Campuses In A Post-Christian, De-Churched, And Unchurched Region Of The United States, Wesley D. Davis

Doctor of Ministry (DMin)

The church is losing influence in America. Furthermore, the COVID-19 pandemic exacerbated the decline in the American church. Polarized on issues of race, politics, masks, and vaccines, church leaders struggled to unite the people of God. Post-pandemic, how do churches and church leaders make more disciples, develop more leaders, and plant more churches in a post-Christian, de-churched, and unchurched culture? The focus of this doctoral dissertation is to present the philosophy of people becoming the church as a solution to the decline of the American church. I discovered the philosophy of people becoming the church over twenty years ago when …


Providing Effective Pastoral Leadership Through Difficult Seasons: Overcoming Barriers To Becoming A Revitalized Church, Joseph Lee Apr 2023

Providing Effective Pastoral Leadership Through Difficult Seasons: Overcoming Barriers To Becoming A Revitalized Church, Joseph Lee

Doctor of Ministry (DMin)

Leading churches in revitalization is challenging. Church plateau, decline, and revitalization have been issues for major denominations for years. Revitalization efforts have produced positive results for some churches, but the overall trend of decline in church attendance and participation in North America persists. One complicating factor in engaging church revitalization is the contextual nature of barriers contributing to plateau and decline. Some barriers may be specific to the churches' time, location, and culture. A second complicating factor impacting church revitalization is the COVID-19 pandemic that began early in 2020. This project explores church leadership dynamics during challenges seasons by focusing …


Virtual Patient/Family Communication In The Acute Care Setting, Kathleen Defigueiredo Apr 2023

Virtual Patient/Family Communication In The Acute Care Setting, Kathleen Defigueiredo

Translational Projects (Open Access)

Patient and family-centered care strategies see patients and families as valuable healthcare team members. Such strategies thus treat these groups as essential clinical partners in providing safe, high-quality care. Participation, collaboration, and shared decision-making are central to this framework. Historically, hospitals have relied on physical presence at the bedside as a prerequisite to engaging families in the shared decision-making process. Visitor restrictions of the COVID-19 pandemic removed the primary strategy for family participation: physical presence. Healthcare organizations rapidly deployed mobile devices to help minimize the exposure of healthcare providers and provide video visits for family members. This deployment was often …


An Investigation Of How Interior Design Elements Can Enhance Customer’S Interest In Fast Fashion Retail Stores In-Person Experience After The Covid-19, Qianyue Tu Apr 2023

An Investigation Of How Interior Design Elements Can Enhance Customer’S Interest In Fast Fashion Retail Stores In-Person Experience After The Covid-19, Qianyue Tu

Theses

The goal of this capstone project is to investigate how interior design elements can enhance customers’ interest in fast fashion retail stores’ in-person experience after the COVID-19 pandemic. To answer the research question, this capstone is organized into three parts which are the literature review, research agenda, and creative agenda. First, the literature review section of this manuscript examines consumer behavior and changes in fast fashion brands before and after the pandemic. The goal of the literature review is to understand four questions: 1) What are changes in consumer behavior after COVID-19? 2) Why are fast fashion brands retailing being …


Institutional Strategies To Maintain And Grow Imaging Research During The Covid-19 Pandemic, Mai-Lan Ho, Corey W Arnold, Summer J Decker, John D Hazle, Elizabeth A Krupinski, David A Mankoff Apr 2023

Institutional Strategies To Maintain And Grow Imaging Research During The Covid-19 Pandemic, Mai-Lan Ho, Corey W Arnold, Summer J Decker, John D Hazle, Elizabeth A Krupinski, David A Mankoff

Faculty, Staff and Student Publications

Understanding imaging research experiences, challenges, and strategies for academic radiology departments during and after COVID-19 is critical to prepare for future disruptive events. We summarize key insights and programmatic initiatives at major academic hospitals across the world, based on literature review and meetings of the Radiological Society of North America Vice Chairs of Research (RSNA VCR) group. Through expert discussion and case studies, we provide suggested guidelines to maintain and grow radiology research in the postpandemic era.


Effect Of Covid-Protocols On Athletic Training Burnout, Harrison C. Garcia Apr 2023

Effect Of Covid-Protocols On Athletic Training Burnout, Harrison C. Garcia

All NMU Master's Theses

Burnout is a psychological condition consisting of emotional exhaustion, depersonalization, and a decreased sense of personal accomplishment and identity. Since the start of the pandemic, a significant increase in burnout has been reported by healthcare professionals, however, there is little known regarding the experiences of athletic trainers (ATs). PURPOSE: The purpose of our study was to investigate the association between burnout and COVID-19 related factors among ATs. METHODS: An electronic survey grouped by the Maslach Burnout Inventory – Human Services Survey, COVID-19 related workplace policies, and demographics was sent to 1,000 ATs through the National Athletic Trainer’s Association email listserv; …


Covid-19 Diagnosis Using Spectral And Statistical Analysis Of Cough Recordings Based On The Combination Of Svd And Dwt, Thabit Sultan Mohammed, Awni Ismail Sultan, Khattab M. Ali Alheeti, Karim Mohammed Aljebory, Hasan Ismail Sultan, Muzhir Shaban Al-Ani Apr 2023

Covid-19 Diagnosis Using Spectral And Statistical Analysis Of Cough Recordings Based On The Combination Of Svd And Dwt, Thabit Sultan Mohammed, Awni Ismail Sultan, Khattab M. Ali Alheeti, Karim Mohammed Aljebory, Hasan Ismail Sultan, Muzhir Shaban Al-Ani

Baghdad Science Journal

Healthcare professionals routinely use audio signals, generated by the human body, to help diagnose disease or assess its progression. With new technologies, it is now possible to collect human-generated sounds, such as coughing. Audio-based machine learning technologies can be adopted for automatic analysis of collected data. Valuable and rich information can be obtained from the cough signal and extracting effective characteristics from a finite duration time interval that changes as a function of time. This article presents a proposed approach to the detection and diagnosis of COVID-19 through the processing of cough collected from patients suffering from the most common …


Revealing Geographic Transmission Pattern Of Covid-19 Using Neighborhood-Level Simulation With Human Mobility Data And Seir Model: A Case Study Of South Carolina, Huan Ning, Zhenlong Li, Shan Qiao, Chengbo Zeng, Jiajia Zhang Ph.D., Bankole Olatosi Ph.D., Xiaoming Li Ph.D. Apr 2023

Revealing Geographic Transmission Pattern Of Covid-19 Using Neighborhood-Level Simulation With Human Mobility Data And Seir Model: A Case Study Of South Carolina, Huan Ning, Zhenlong Li, Shan Qiao, Chengbo Zeng, Jiajia Zhang Ph.D., Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Direct human physical contact accelerates COVID-19 transmission. Smartphone mobility data has emerged as a valuable data source for revealing fine-grained human mobility, which can be used to estimate the intensity of physical contact surrounding different locations. Our study applied smartphone mobility data to simulate the second wave spreading of COVID-19 in January 2021 in three major metropolitan statistical areas (Columbia, Greenville, and Charleston) in South Carolina, United States. Based on the simulation, the number of historical county-level COVID-19 cases was allocated to neighborhoods (Census block groups) and points of interest (POIs), and the transmission rate of each allocated place was …


Work-Related Burnout, Compassion Fatigue, And Nurse Intention To Leave The Profession During Covid-19, Jacqueline Christianson, Norah L. Johnson, Amanda Nelson, Maharaj Singh Apr 2023

Work-Related Burnout, Compassion Fatigue, And Nurse Intention To Leave The Profession During Covid-19, Jacqueline Christianson, Norah L. Johnson, Amanda Nelson, Maharaj Singh

College of Nursing Faculty Research and Publications

The purpose of this mixed-method study was to understand the relationships between work-related burnout (WRB), compassion fatigue (CF), and intention to leave the nursing profession. The Job Demands-Resources model was used to predict intention to leave as a function of WRB, CF, and caring for COVID-19 patients in a sample of 1299 US nurses. Greater WRB and CF scores were associated with intention to leave the profession. Contrary to prior research, working with COVID-19 patients was associated with greater intention to stay in nursing. Personal finances may represent the rationale for nurses to choose to stay nurses despite burnout.


Lessons Learned From Covid-19, Donald Tucker Dds Apr 2023

Lessons Learned From Covid-19, Donald Tucker Dds

The New York State Dental Journal

Dentistry and society, in general, must seek out accurate information regarding the virus and follow scientifically established guidelines to mitigate serious outcomes.


Covid-19 Vaccine Hesitancy And Vaccination Rate Among The Latino Population In South Carolina, Brynn E. Lynagh Apr 2023

Covid-19 Vaccine Hesitancy And Vaccination Rate Among The Latino Population In South Carolina, Brynn E. Lynagh

Senior Theses

It is common knowledge that COVID-19 disproportionately impacts racial and ethnic minorities in the United States. Furthermore, these sects of the population exhibit increased vaccine hesitancy and lower vaccination rates as compared to the aggregated population of the United States, furthering the risk posed by COVID-19 to these communities. In particular, this study focuses on the Latino population in South Carolina, the vaccination rate among this community, and the perspectives which contributed to their vaccination decision. Two hundred Spanish and Portuguese speaking residents of South Carolina were interviewed using a paper survey conducted by pre-trained interviewers. The survey gathered data …


Prevalence Of Sars-Cov-2 Antibodies In Liberty University Student Population, Emily Bonus Apr 2023

Prevalence Of Sars-Cov-2 Antibodies In Liberty University Student Population, Emily Bonus

Senior Honors Theses

In 2020, the virus SARS-CoV-2 gained attention as it spread around the world. Its antibodies are poorly understood, and little research focuses on those with few COVID-19 complications yet large numbers of close contacts: university students. This longitudinal study recorded SARS-CoV-2 antibody presence in 107 undergraduate Liberty University students twice during early 2021. After extensive data cleaning and the application of various statistical tests and ANOVAs, the data seems to show that in the case of COVID-19 infections, SARS-CoV-2 IgM antibodies are immediately produced, and then IgG antibodies follow later. However, the COVID-19 vaccine causes the production of both IgM …


The Effects Of Covid-19 On Cybersecurity And Securing A Post-Covid World, Ryan Pizzo Apr 2023

The Effects Of Covid-19 On Cybersecurity And Securing A Post-Covid World, Ryan Pizzo

Senior Honors Theses

The world became hardly recognizable throughout the COVID-19 pandemic as the normal state of the world was disrupted. In addition to affecting everyday life, the pandemic touched every industry, especially that of cybersecurity. To properly remediate for the future of cybersecurity, the trends in cybercrime seen throughout the pandemic warrant further investigation. An overall increase in cybercrime was clearly observed with no signs of plateauing. This trend was paired with developing sophistication of cybercrime means and methods. In response to this, a defense-in-depth strategy focusing on a layered defense approach strengthens an organization’s security posture. Focusing on every policy and …


“It Looks Like The Future But Feels Like The Past”: Oral (Hi)Stories Of Appalachia As Covid-19 News Stories, Ashley Reid Mcgraw Apr 2023

“It Looks Like The Future But Feels Like The Past”: Oral (Hi)Stories Of Appalachia As Covid-19 News Stories, Ashley Reid Mcgraw

Theses and Dissertations

Oral historians have often felt obligated to collect stories during disasters and crises, to preserve recollections of experiences and trauma of those affected. During the onset of COVID-19 in the United States, this surge was certainly present. Appalachia, although its boundaries are contested, has a strong association with oral histories, and thus was the focus of one project in particular: a collaboration with the Blue Ridge Public Radio and the Foxfire Appalachian Heritage Museum to collect, curate, publish, and broadcast oral histories of "local" individuals. But what does it mean to be local, in a region as broad as Appalachia? …


Are The Teachers Alright?: High School Teachers’ Use Of Emotional Labor Strategies In The Covid-19 Context And Its Effect On The Profession’S Sustainability, Nina C. Benegas Apr 2023

Are The Teachers Alright?: High School Teachers’ Use Of Emotional Labor Strategies In The Covid-19 Context And Its Effect On The Profession’S Sustainability, Nina C. Benegas

LMU Theses and Dissertations

Teacher burnout during the pandemic has resulted in a mass exodus of teachers that, compounded with consistently low enrollment in teacher preparation programs, has caused a severe and catastrophic teacher shortage. This qualitative study investigated teacher perceptions of pandemic-related workload and emotional stress and their effects on job satisfaction and burnout. The dissertation study consisted of semi-structured interviews of sixteen current or former high school educators who taught before and during the COVID-19 pandemic. Findings suggest a wide range of disruptions to teachers’ preexisting professional responsibilities and additions to what has been considered to constitute a teacher’s typical workload, particularly: …


Assessing The Impact Of The Covid-19 Pandemic On Project Management Methodologies, Adrian Leung Apr 2023

Assessing The Impact Of The Covid-19 Pandemic On Project Management Methodologies, Adrian Leung

LMU Theses and Dissertations

This research paper explores the impact of COVID-19 and the shift to remote work on project management practices across multiple industries. Through interviews with project managers, the study finds that companies with pre-existing remote work policies were better equipped to handle the transition to remote work. In contrast, companies without pre-existing policies faced increased challenges in communication, team morale, and workload management. The study also highlights the struggle to maintain work-life balance, the importance of communication, and the need to address technical difficulties. Project managers emphasized the importance of accountability and maintaining productivity during remote work. Overall, the study finds …


Otolaryngology Consultations For Covid-19 Patients: A Retrospective Cohort Study Of Indications, Interventions, And Considerations, Kunal R Shetty, Brady J Anderson, Jumah G Ahmad, Lucy X Liu, Kevin Chow, Samuel G Erickson, Shohan Shetty, Amber U Luong Apr 2023

Otolaryngology Consultations For Covid-19 Patients: A Retrospective Cohort Study Of Indications, Interventions, And Considerations, Kunal R Shetty, Brady J Anderson, Jumah G Ahmad, Lucy X Liu, Kevin Chow, Samuel G Erickson, Shohan Shetty, Amber U Luong

Faculty, Staff and Student Publications

OBJECTIVE: To identify differences in inpatient otolaryngology consultations and interventions for patients based on COVID-19.

METHODS: Records were reviewed for all patients for whom otolaryngology was consulted at a high-volume tertiary care hospital from April 30, 2020 to October 1, 2020. Demographic information, length of stay, COVID-19 status, indication for consultation, and otolaryngology interventions were recorded. Statistical analysis was performed using R software.

RESULTS: Bleeding composed a significantly higher proportion of otolaryngology consults in COVID-19 positive patients (28% vs. 8.4%, p

CONCLUSION: Bleeding and associated interventions comprised the predominant discrepancy between COVID-19 positive and negative patients in our cohort. We …


Just-In-Time Decision Making: Preliminary Findings Of A Goals Of Care Rapid Response Team, Donna S Zhukovsky, Yvonne Heung, Parema Enriquez, Nelda Itzep, Zhanni Lu, Nico Nortje, Penny Stanton, Angelique Wong, Eduardo Bruera Apr 2023

Just-In-Time Decision Making: Preliminary Findings Of A Goals Of Care Rapid Response Team, Donna S Zhukovsky, Yvonne Heung, Parema Enriquez, Nelda Itzep, Zhanni Lu, Nico Nortje, Penny Stanton, Angelique Wong, Eduardo Bruera

Faculty, Staff and Student Publications

CONTEXT: The COVID-19 pandemic placed the issue of resource utilization front and center. Our comprehensive cancer center developed a Goals of Care Rapid Response Team (GOC RRT) to optimize resource utilization balanced with goal-concordant patient care.

OBJECTIVES: Primary study objective was to evaluate feasibility of the GOC RRT by describing the frequency of consultations that occurred from those requested. Secondary objectives included adherence to consultation processes in terms of core team member participation and preliminary efficacy in limiting care escalation.

METHODS: We conducted a retrospective chart review of patients referred to GOC RRT (3/23/2020-9/30/2020). Analysis was descriptive. Categorical variables were …


Sars-Cov-2 Restructures Host Chromatin Architecture, Ruoyu Wang, Joo-Hyung Lee, Jieun Kim, Feng Xiong, Lana Al Hasani, Yuqiang Shi, Erin N Simpson, Xiaoyu Zhu, Yi-Ting Chen, Pooja Shivshankar, Joanna Krakowiak, Yanyu Wang, David M Gilbert, Xiaoyi Yuan, Holger K Eltzschig, Wenbo Li Apr 2023

Sars-Cov-2 Restructures Host Chromatin Architecture, Ruoyu Wang, Joo-Hyung Lee, Jieun Kim, Feng Xiong, Lana Al Hasani, Yuqiang Shi, Erin N Simpson, Xiaoyu Zhu, Yi-Ting Chen, Pooja Shivshankar, Joanna Krakowiak, Yanyu Wang, David M Gilbert, Xiaoyi Yuan, Holger K Eltzschig, Wenbo Li

Faculty, Staff and Student Publications

Some viruses restructure host chromatin, influencing gene expression, with implications for disease outcome. Whether this occurs for SARS-CoV-2, the virus causing COVID-19, is largely unknown. Here we characterized the 3D genome and epigenome of human cells after SARS-CoV-2 infection, finding widespread host chromatin restructuring that features widespread compartment A weakening, A-B mixing, reduced intra-TAD contacts and decreased H3K27ac euchromatin modification levels. Such changes were not found following common-cold-virus HCoV-OC43 infection. Intriguingly, the cohesin complex was notably depleted from intra-TAD regions, indicating that SARS-CoV-2 disrupts cohesin loop extrusion. These altered 3D genome/epigenome structures correlated with transcriptional suppression of interferon response genes …


Covid-19 And Employee Job Performance Trajectories: The Moderating Effect Of Different Sources Of Status, Xin Liu, Xiaoming Zheng, Byron Y Lee, Yu Yu, Mengyi Zhang Apr 2023

Covid-19 And Employee Job Performance Trajectories: The Moderating Effect Of Different Sources Of Status, Xin Liu, Xiaoming Zheng, Byron Y Lee, Yu Yu, Mengyi Zhang

Faculty, Staff and Student Publications

This study investigates the impact of the COVID-19 pandemic on employee job performance trajectories, and further examines the moderating effects of different sources of status. Drawing from event system theory (EST), we propose that employee job performance decreases upon COVID-19 onset, but gradually increases during the postonset period. Furthermore, we argue that status from society, occupation, and workplace functions to moderate such performance trajectories. We test our hypotheses with a unique dataset of 708 employees that combines survey responses and job performance archival data over 21 consecutive months (10,808 observations) spanning the preonset, onset, and postonset periods of the initial …


Covid Time: How Quarantine Affects Feelings Of Elapsed Time, Minju Han, Guy Voichek, Gal Zauberman Apr 2023

Covid Time: How Quarantine Affects Feelings Of Elapsed Time, Minju Han, Guy Voichek, Gal Zauberman

Research Collection Lee Kong Chian School Of Business

The lockdowns imposed in response to the COVID-19 pandemic abruptly upended people's lives and daily structure. In this survey of 1,506 Americans conducted in June 2020, we test how quarantine affects feelings of elapsed time (the subjective temporal distance from an event). We find that feelings of elapsed time are determined either by how people spent their time in quarantine or by how much time since an event was spent in quarantine, depending on whether people are still in quarantine at the time of evaluation. Specifically, whether people quarantined alone and the extent to which they maintained a temporal structure …


Durations Of Dockless E-Scooter Trips Before And During The Covid-19 Pandemic In Austin, Tx: An Analysis Using Hazard-Based Duration Models, Amin Azimian, Junfeng Jiao Apr 2023

Durations Of Dockless E-Scooter Trips Before And During The Covid-19 Pandemic In Austin, Tx: An Analysis Using Hazard-Based Duration Models, Amin Azimian, Junfeng Jiao

Research Collection College of Integrative Studies

The pandemic arising from the 2019 coronavirus disease has significantly affected all facets of human life across the world, including economies and transportation systems, thereby changing people’s travel behaviors. This research was aimed at exploring the relationship between socio-economic factors and e-scooter trip durations before and during the pandemic. We developed a hazard-based duration approach and estimated multiple spatial and non-spatial models on the basis of 2019 and 2020 dockless e-scooter data collected from the City of Austin’s Open Data Portal. The results indicated an overall increase in e-scooter trip durations after the pandemic. Moreover, analysis of variables revealed potential …


Using Thermal Remote Sensing To Quantify Impact Of Traffic On Urban Heat Islands During Covid, My-Thu Tran, Bo Yang Apr 2023

Using Thermal Remote Sensing To Quantify Impact Of Traffic On Urban Heat Islands During Covid, My-Thu Tran, Bo Yang

Mineta Transportation Institute

A three-month lockdown in the U.S. at the beginning of the COVID-19 outbreak in 2020 greatly reduced the traffic volume in many cities, especially large metropolitan areas such as the San Francisco Bay Area. This research explores the impact of transportation on climate change by using remote sensing technology and statistical analysis during the COVID-19 lockdown. Using thermal satellite data, this research measures the intensity of the urban heat island, the main driver for climate change during the urbanization process. The research team acquired morning and afternoon MODIS data in the same periods in 2019 before the pandemic and 2020 …


Utilizing The System Engineering Trade Study Analysis Method To Analyze Patient Aeromedical Evacuation, Sara Shaghaghi, Jeremy M. Slagley, Michael E. Miller, Gaiven Varshney Apr 2023

Utilizing The System Engineering Trade Study Analysis Method To Analyze Patient Aeromedical Evacuation, Sara Shaghaghi, Jeremy M. Slagley, Michael E. Miller, Gaiven Varshney

Faculty Publications

The US Air Force has gone through many aeromedical patient isolation transport system designs. The first designs were developed in response to the Ebola outbreak in 2014 and, more recently, the COVID-19 pandemic. The trade study analysis part of the system engineering design method was used to analyze the historic and current aeromedical patient contamination control transport systems. A trade study is a process that evaluates alternatives based upon various “-ilities”, such as reconfigurability, flexibility, durability, cost, and more, and performs a systematic analysis to aid designers in producing a ‘good’ design alternative given the large set of possible solutions. …


Incidence Rates Of Medically Attended Covid-19 In Infants Less Than 6 Months Of Age, Isabel Griffin, Stephanie A Irving, Carmen Sofia Arriola, Angela P Campbell, De-Kun Li, Fatimah S Dawood, Caroline Doughty-Skierski, Jeannette R Ferber, Nickolas Ferguson, Louise Hadden, Jillian T Henderson, Mary Juergens, Venkatesh Kancharla, Allison L Naleway, Gabriella Newes-Adeyi, Erin Nicholson, Roxana Odouli, Lawrence Reichle, Mo Sanyang, Kate Woodworth, Flor M Munoz Apr 2023

Incidence Rates Of Medically Attended Covid-19 In Infants Less Than 6 Months Of Age, Isabel Griffin, Stephanie A Irving, Carmen Sofia Arriola, Angela P Campbell, De-Kun Li, Fatimah S Dawood, Caroline Doughty-Skierski, Jeannette R Ferber, Nickolas Ferguson, Louise Hadden, Jillian T Henderson, Mary Juergens, Venkatesh Kancharla, Allison L Naleway, Gabriella Newes-Adeyi, Erin Nicholson, Roxana Odouli, Lawrence Reichle, Mo Sanyang, Kate Woodworth, Flor M Munoz

Faculty, Staff and Students Publications

BACKGROUND: Studies suggest infants may be at increased risk of severe coronavirus disease 2019 (COVID-19) relative to older children, but few data exist regarding the incidence of COVID-19 episodes and associated risk factors. We estimate incidence rates and describe characteristics associated with medically attended COVID-19 episodes among infants younger than 6 months of age.

METHODS: We analyzed electronic medical record data from a cohort of infants born March 1, 2020-February 28, 2021. Data from 3 health care delivery systems included demographic characteristics, maternal and infant outpatient visit and hospitalization diagnoses and severe acute respiratory syndrome coronavirus syndrome 2 (SARS-CoV-2) test …


The Virtual Classroom: What Can Be Learned From The Covid-19 Lockdown, James L. Nations Apr 2023

The Virtual Classroom: What Can Be Learned From The Covid-19 Lockdown, James L. Nations

Senior Theses

This paper seeks to examine the teaching practices utilized during the initial COVID-19 lockdown in higher education. This forced switch to the virtual classroom forced many professors to make innovative changes to adapt to this change in teaching modality. These changes can now be examined and evaluated for potential future application. By reviewing the current literature, performing an analysis of grades from Fall 2017 through Summer 2022, and interviewing select professors at the University of South Carolina, this paper seeks to illuminate some of the potential issues that arise when adapting in-person curriculums to the virtual classroom as well as …


Impact Of Covid-19 On Outcomes Of Patients Hospitalized With Stemi: A Nationwide Propensity-Matched Analysis, Akshay Goel, Aaqib H Malik, Dhrubajyoti Bandyopadhyay, Ameesh Isath, Rahul Gupta, Adrija Hajra, Rishi Shrivastav, Salim S Virani, Gregg C Fonarow, Carl J Lavie, Srihari S Naidu Apr 2023

Impact Of Covid-19 On Outcomes Of Patients Hospitalized With Stemi: A Nationwide Propensity-Matched Analysis, Akshay Goel, Aaqib H Malik, Dhrubajyoti Bandyopadhyay, Ameesh Isath, Rahul Gupta, Adrija Hajra, Rishi Shrivastav, Salim S Virani, Gregg C Fonarow, Carl J Lavie, Srihari S Naidu

Faculty, Staff and Students Publications

Patients with ST-segment elevation myocardial infarction (STEMI) and concurrent coronavirus disease 2019 (COVID-19) have been reported to have poor outcomes. However, previous studies are small and limited. The National Inpatient Sample database for the year 2020 was queried to identify all adult hospitalizations with a primary diagnosis of STEMI, with and without concurrent COVID-19. A 1:1 propensity score matching was performed. A total of 159,890 hospitalizations with a primary diagnosis of STEMI were identified. Of these, 2210 (1.38%) had concurrent COVID-19. After propensity matching, STEMI patients with concurrent COVID-19 had a significantly higher mortality (17.8% vs 9.1%, OR 1.96, P< 0.001), lower likelihood to receive same-day percutaneous coronary intervention (PCI) (63.6% vs 70.6%, P = 0.019), with a trend towards lower overall PCI (74.9% vs 80.2%, P = 0.057) and significantly lower coronary artery bypass grafting) (3.0% vs 6.8%, P = 0.008) prior to discharge, compared with STEMI patients without COVID-19. The prevalence of cardiogenic shock, need for mechanical circulatory support, extracorporeal membrane oxygenation, cardiac arrest, acute kidney injury (AKI), dialysis, major bleeding and stroke were not significantly different between the groups. COVID-19-positive STEMI patients who received same-day PCI had significantly lower odds of in-hospital mortality (adjusted OR 0.42, 95% CI 0.20-0.85, P = 0.017). STEMI patients with concurrent COVID-19 infection had a significantly higher (almost 2 times) in-hospital mortality, and lower likelihood of receiving same-day PCI, overall (any-day) PCI, and CABG during their admission, compared with STEMI patients without COVID-19.


Nfkb2 Haploinsufficiency Identified Via Screening For Ifn-Α2 Autoantibodies In Children And Adolescents Hospitalized With Sars-Cov-2-Related Complications, Aaron Bodansky, Sara E Vazquez, Janet Chou, Tanya Novak, Amer Al-Musa, Cameron Young, Margaret Newhams, Suden Kucukak, Laura D Zambrano, Anthea Mitchell, Chung-Yu Wang, Kristin Moffitt, Natasha B Halasa, Laura L Loftis, Stephanie P Schwartz, Tracie C Walker, Elizabeth H Mack, Julie C Fitzgerald, Shira J Gertz, Courtney M Rowan, Katherine Irby, Ronald C Sanders, Michele Kong, Jennifer E Schuster, Mary A Staat, Matt S Zinter, Natalie Z Cvijanovich, Keiko M Tarquinio, Bria M Coates, Heidi R Flori, Mary K Dahmer, Hillary Crandall, Melissa L Cullimore, Emily R Levy, Brandon Chatani, Ryan Nofziger, Overcoming Covid-19 Network Study Group Investigators, Raif S Geha, Joseph Derisi, Angela P Campbell, Mark Anderson, Adrienne G Randolph Apr 2023

Nfkb2 Haploinsufficiency Identified Via Screening For Ifn-Α2 Autoantibodies In Children And Adolescents Hospitalized With Sars-Cov-2-Related Complications, Aaron Bodansky, Sara E Vazquez, Janet Chou, Tanya Novak, Amer Al-Musa, Cameron Young, Margaret Newhams, Suden Kucukak, Laura D Zambrano, Anthea Mitchell, Chung-Yu Wang, Kristin Moffitt, Natasha B Halasa, Laura L Loftis, Stephanie P Schwartz, Tracie C Walker, Elizabeth H Mack, Julie C Fitzgerald, Shira J Gertz, Courtney M Rowan, Katherine Irby, Ronald C Sanders, Michele Kong, Jennifer E Schuster, Mary A Staat, Matt S Zinter, Natalie Z Cvijanovich, Keiko M Tarquinio, Bria M Coates, Heidi R Flori, Mary K Dahmer, Hillary Crandall, Melissa L Cullimore, Emily R Levy, Brandon Chatani, Ryan Nofziger, Overcoming Covid-19 Network Study Group Investigators, Raif S Geha, Joseph Derisi, Angela P Campbell, Mark Anderson, Adrienne G Randolph

Faculty, Staff and Students Publications

BACKGROUND: Autoantibodies against type I IFNs occur in approximately 10% of adults with life-threatening coronavirus disease 2019 (COVID-19). The frequency of anti-IFN autoantibodies in children with severe sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is unknown.

OBJECTIVE: We quantified anti-type I IFN autoantibodies in a multicenter cohort of children with severe COVID-19, multisystem inflammatory syndrome in children (MIS-C), and mild SARS-CoV-2 infections.

METHODS: Circulating anti-IFN-α2 antibodies were measured by a radioligand binding assay. Whole-exome sequencing, RNA sequencing, and functional studies of peripheral blood mononuclear cells were used to study any patients with levels of anti-IFN-α2 autoantibodies exceeding …