Digital Commons Network^™

Evaluation Of D-Dimer Level In Covid-19 Patients, Amal Malik, Noor Kadhim Mohamed-Jawad, Hiba Dawood, Ali Adnan Mohsin

Iraqi National Journal of Medicine

Background: The COVID-19 pandemic is associated with prothrombotic complications, leading to increased morbidity and mortality. D-dimer, a fibrin degradation product, serves as a biomarker for coagulation abnormalities. This study evaluates the role of D-dimer in predicting disease severity and hospitalization in COVID-19 patients. Aim: To assess correlations between D-dimer levels and age, gender, comorbidities, disease severity, and hospitalization needs in COVID-19 patients. Methods: A retrospective analysis of 78 COVID-19-positive patients admitted to an outpatient clinic was conducted. Data on demographics, comorbidities, vaccination status, disease severity, and admission D-dimer levels were analyzed using statistical tests (t-tests, chi-square, Mann-Whitney U). Results: The …

Tanzania's Compliance To International Covid-19 Standards: Determinants And Extent, Maria Joseph Tairo, Boniphace Shimba Francis

Tanzania Journal of Sociology

This article assesses Tanzania’s level of compliance to international COVID-19 preventive measures, with a focus on the political, economic, and socio-cultural factors that influenced the adherence. A qualitative research approach with descriptive design were adopted. Data were collected through semi-structured interviews with 28 purposively selected participants, including healthcare workers and government officials from Dar es Salaam and Dodoma. Moreover, relevant documents from health sector were reviewed. Thematic analysis was performed using Computer-Assisted Qualitative Data Analysis Software (CAQDAS). The findings revealed that political leadership played a pivotal role in shaping compliance levels. The 5th regime demonstrated skepticism toward WHO guidelines and …

A Phenomenological Study Of The Mental Health Needs Of High School Youth In A Rural Community Post Covid-19 Pandemic, Maritza Gonzalez

Doctoral Dissertations and Projects

The purpose of this phenomenological study is to describe former high school students’ experiences with mental health struggles while in high school during the COVID-19 pandemic in a rural Texas Public Independent School District. Mental illness increased among youth during the prolonged pandemic period of time and many of the pervasive mental health concerns have not been addressed effectively in the aftermath. As a result, a growing number of concerns pertaining to the mental health wellbeing of K-12 children continues to be on the rise. Thus, it is of utmost importance to learn more about the experiences of our youth …

Unravelling Impact Of Comorbidities On Mortality Risks In Ckd Patients During The Covid-19 Pandemic: An Explainable Ai-Driven Study, Zeinab Abdollahi, Lin Huo, Donald Fraser, Shang-Ming Zhou

School of Nursing and Midwifery

ObjectivesThe chronic kidney disease (CKD) patients were at high risk for severe clinical complications during the COVID-19 pandemic. Our objectives were to evaluate comorbidity prevalence; predict mortality risks for CKD patients during the pandemic; assess how various health factors interact to influence mortality; and provide insights for targeted prevention strategies.MethodWe analysed data from 186,396 CKD patients in Mexico during the entire pandemic (Jan 2020- May 2023). Explainable artificial intelligence (XAI) methods with extreme gradient boosting (XGBoost) models and Shapley Additive Explanations (SHAP) were developed to predict mortality for CKD patients with model interpretations. Different metrics were used to comprehensively evaluate …

The Computationally Designed Tri2-2 Miniprotein Inhibitor Protects Against Multiple Sars-Cov-2 Omicron Variants, Jimin Lee, James Brett Case, Young-Jun Park, Rashmi Ravichandran, Daniel Asarnow, M Alejandra Tortorici, Jack T Brown, Shilpa Sanapala, Lauren Carter, David Baker, Michael S Diamond, David Veesler

2020-Current year OA Pubs

The continued evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has compromised neutralizing antibody responses elicited by prior infection or vaccination and abolished the utility of most monoclonal antibody therapeutics. We previously described a computationally-designed, homotrimeric miniprotein inhibitor, designated TRI2-2, that protects mice against pre-Omicron SARS-CoV-2 variants. Here, we show that TRI2-2 exhibits broadly neutralizing activity of SARS-CoV-2 variants and protects mice against BQ.1.1, XBB.1.5 and BA.2.86 challenge when administered intranasally post-exposure. The resistance of TRI2-2 to viral escape by most variants and the ability to deliver it directly to the upper airways highlight the potential of the multivalent …

Covid-19 Infection And Hypertension In Correlation With Race, Elizabeth Durkin

The Pegasus Review: UCF Undergraduate Research Journal

Healthcare disparities exist in the U.S. between different races. This study investigated the frequency of COVID-19 infections and hypertension cases among five different racial groups (White, Black, Asian, Native American, and Native Hawaiian). The study also examined the correlation between COVID-19 infections and hypertension with the hypothesis that because of disease predisposition and socioeconomic barriers, Black populations would have the highest rates of COVID-19 infections and hypertension. We used data from the Kaiser Family Foundation regarding COVID-19 cases and race in conjunction with Census population data to determine whether COVID-19 case frequency means differed by race. Data on hypertension and …

Optimal Intervention Strategies In Age-Structured Sirvd Model: Epidemiological And Economic Analysis Of Covid-19 In Korea, Joon Chun, Melisa Hendrata

Spora: A Journal of Biomathematics

This study employed an age-structured Susceptible-Infected-Recovered-Vaccinated-Deceased (SIRVD) model to design optimal COVID‑19 intervention strategies by integrating epidemiological dynamics with economic costs. Using empirical data from South Korea, we estimated transmission parameters and analyzed quarantine-based non-pharmaceutical interventions (NPIs) alongside targeted vaccination scenarios. Our results indicated that a stronger form of mild NPI (upper range of Level I), when combined with targeted vaccination that prioritized seniors, achieved substantial reductions in infection peaks and overall economic burden. These findings underscore the effectiveness of age-specific strategies in epidemic management and offer critical insights for policymakers seeking balanced, resource-efficient approaches.

Factors Correlated With State-Level Variation In Grocery Consumption Changes During The Covid-19 Pandemic, Sun Young Byun

CMC Senior Theses

In this paper, I employ a two-part empirical strategy to explore the effects of the COVID-19 pandemic on grocery consumption across U.S. states. First, I use the United States Department of Agriculture's Weekly Retail Food Sales data from 2018-2023 to estimate a time-series panel model. I use the results to test three hypotheses regarding state-level variation in consumption changes and impacts in the initial pandemic period, the remaining pandemic period, and the post-pandemic period. Second, I use the estimated state-level effects as dependent variables in cross-sectional regressions to test three hypotheses linking variation in state-level consumption patterns to economic, demographic, …

Examining First-Generation College Students’ Academic, Social, Emotional, And Financial Experiences During The Coronavirus 2019 (Covid-19) Pandemic, Anika Dorsey Good

Theses and Dissertations

This qualitative phenomenological study investigates the experiences of Black first-generation college students enrolled at a two-year college in the Northeast region of the United States during the COVID-19 pandemic. The study examines the narratives of a historically marginalized population in order to uncover the academic, social, and personal challenges they experienced due to the global health crisis. It also aims to explore the impacts, barriers, and resilience strategies of students through semi-structured interviews, reflective journal writing, and related artifacts. Research has shown that Black college students remain a historically underserved group enrolled in higher education. The Department of Education's National …

Qualitative Exploration Of Covid-19 Vaccine Uptake Among Healthcare Workers In Sierra Leone: Do The ‘Trusted Messengers’ Trust The Vaccine?, Ifeolu David, Enid Schatz, Wilson Majee

Population Health Leadership and Analytics Faculty Publications and Presentations

Introduction

Vaccine hesitancy is a global issue, and the important role of healthcare workers in addressing vaccine hesitancy is well documented. However, there is limited theory-guided research on the uptake of COVID-19 vaccinations among healthcare workers in low- and middle-income countries (LMICs). This study examined COVID-19 vaccine uptake among healthcare workers in Sierra Leone and assessed the relevance of the 5C model—which posits that vaccine uptake is shaped by confidence, complacency, constraints, calculation and collective responsibility—in explaining their vaccination attitudes, intentions and behaviours.

Methods

24 indepth interviews were conducted in 2022 with healthcare workers in Freetown, Makeni and Kenema. The …

Chronic Absenteeism In Long Island Secondary Schools: A Mixed-Methods Study Of Post-Covid-19 Trends And Professional Perceptions, William M. Gibbons

Selected Full Text Dissertations, 2011-

Recent educational research studies have shown that an alarming number of students are chronically absent from school, a trend that is occurring both nationwide and in New York State. While this number had been slowly increasing before the COVID-19 pandemic, it has accelerated significantly following the pandemic. This increase in chronic absenteeism is also prevalent across Nassau and Suffolk County high schools; there has been a large increase in the percentage of students who are chronically absent in high school since the COVID-19 pandemic. Experts warn that this increased number can lead to multiple negative consequences for students, including social …

Trends Among Suspected Opioid Overdose Emergency Medical Service (Ems) Incidents In Georgia From 2019-2023, Ashton Harris

College of Graduate Studies: Theses & Dissertations

Opioid overdoses remain a problem in the United States, underscoring the need for additional surveillance tools to monitor trends in opioid overdoses. Emergency Medical Services (EMS) data is a timely surveillance method that captures more potential overdoses than hospitals by representing the pre-hospital setting. Research questions in the study assess EMS responses to suspect opioid overdose incidents from 2019-2023 in Georgia to encompass the following characteristics: timeframe (pre, during, post-pandemic), urban versus rural counties, race/ethnicity, categorical type of first responder, mean dosage of naloxone in milligrams administered, and death. 84,359 records meeting the inclusion criteria were initially retrieved from the …

Understanding Addiction As A Disease: College Students’ Perspectives On Substance Use In The Covid-19 Era, Aditi Rudrashetty

Athena: Undergraduate Research and Literary Journal

This research explores the neurological basis of addiction as a disease and how the exacerbation of external factors has contributed to negative perceptions of addiction. Specifically, it examines the COVID-19 pandemic and contemporary college student experiences as contextual factors influencing attitudes toward substance use disorders. Negative perceptions contribute to stigma, reduce help-seeking behavior, and influence policy responses, hindering effective support and recovery for individuals with substance use disorders. By examining these perceptions, this study contributes to understanding how addiction is conceptualized and potentially addressed in public health and policy contexts. Surveys and semi-structured interviews were conducted with college students to …

School Reopenings And Adhd Medication Utilization: Evidence From Covid-19 Policy Variation, Madeline C. Levey

CMC Senior Theses

This paper investigates how variation in K–12 school reopening policies across U.S. states during the COVID-19 pandemic affected Medicaid-covered ADHD stimulant medication prescriptions. Using an event study and difference-in-differences framework with state and time fixed effects, I exploit variation in the timing and mode of school reopening across states from 2017 to 2022. School reopening data are drawn from a national district-level panel tracking the share of students attending school in-person, hybrid, or virtually; prescription outcomes are from the Centers for Medicare & Medicaid Services State Drug Utilization Data. The event study reveals a sharp decline in ADHD prescriptions at …

Arrhythmogenic Covid-19 Myocarditis Presenting As Out-Of-Hospital Ventricular Fibrillation Arrest With Preserved Ejection Fraction, Mohamed Ahmed, Elinor Barsh, Dmitriy Scherbak

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Viral Misunderstandings: Reddit Posts And The Covid-19 Infodemic, Julia C. Knutson

Scripps Senior Theses

Information epidemics or “infodemics” became the center of misinformation conversations, due to a global increase in information spread surrounding the COVID-19 pandemic. While many academic scholars and institutions, such as the World Health Organization (WHO) attribute the cause of infodemics to anti-science attitudes and the public’s lack of scientific literacy, scholars in Science, Technology, and Society argue that analyzing misinformation within these isolated bounds limits our understanding of its underlying social and historical contexts. Using the COVID-19 pandemic as a case study for misinformation analysis reveals a gap in our current understanding of how people who resonate with or spread …

Facebooking Under Crisis: A Comparative Study Of Online French And American Mutual Aid Organizing During The Covid-19 Pandemic, Clare Reimers-Hejnal

Scripps Senior Theses

This thesis studies the political discussions, practices, and projects that emerged through mutual aid Facebook groups based in France and the United States during the COVID-19 pandemic. Of particular interest is how these online spaces and the Facebook users that comprised them understood their mutual aid organizing in relationship to specific themes, including but not limited to: the COVID-19 pandemic as a "crisis", the role of government presence or absence in the wellbeing of the public, and the concept of collective yet differentiated struggle. Chapter 1 looks at four Facebook pages based in the greater Paris area: Entraide Danube, Clichy …

Evaluation Of Interventions For Cognitive Symptoms In Long Covid: A Randomized Clinical Trial, David S Knopman, Deborah Koltai, Daniel T Laskowitz, Jacqueline Becker, Leigh Charvet, Juan Wisnivesky, Alex Federman, Adam Silverstein, Yuliya Lokhnygina, Giuseppina Pilloni, Michelle Haddad, Henry Mahncke, Tom Van Vleet, Rong Huang, Wendy Cox, Diana Terry, Jeannie Karwowski, Netia Mccray, Jenny J Lin, Grace A Mccomsey, Upinder Singh, Linda N Geng, Helen Y Chu, Rebecca Reece, James Moy, Zoe Arvanitakis, Sairam Parthasarathy, Thomas F Patterson, Aditi Gupta, Luis Ostrosky-Zeichner, Jeffrey Parsonnet, Elaine T Kiriakopoulos, Tamara G Fong, Janet Mullington, Sarah Jolley, Nirav S Shah, Sarah Shizuko Morimoto, Joyce K Lee-Iannotti, William D S Killgore, Brigid Dwyer, William Stringer, Carmen Isache, Jennifer A Frontera, Jerry A Krishnan, Ashley O'Steen, Melissa James, Barrie L Harper, Kanecia O Zimmerman

Faculty, Staff and Student Publications

Importance: Treatment for cognitive dysfunction due to postacute sequelae of long COVID (ie, symptoms of fatigue, malaise, weakness, confusion that persist beyond 12 weeks after an initial COVID infection) remains a significant unmet need.

Objective: To test evidence-based rehabilitation strategies for improving cognitive symptoms in persons with long COVID.

Design, setting, and participants: This was a 5-arm, multicenter, randomized clinical trial of 3 remotely delivered interventions conducted between August 17, 2023, and June 10, 2024. The study took place at 22 trial sites and included the screening of individuals with cognitive long COVID.

Interventions: Participants were randomized to 1 of …

If I Only Had The Words (To Tell You): Billy Joel Lyrics In Legal And Medical Scholarship, Seuli Bose Brill, Christian H. Brill

Touro Law Review

Law and medicine are often considered to be among the least accessible professions, partly because of the heavy use of non colloquial jargon. This article examines more than 150 instances in which Billy Joel’s lyrics have been used to improve the accessibility of legal and medical scholarship. Legal and medical professionals have used the words of the “Piano Man” to discuss a variety of topics—everything from civil procedure to property rights and the COVID-19 pandemic to colorectal surgery. Nontraditional communications techniques of this type do not just contribute to the body of legal and medical scholarship; they also help professionals …

Existential Reckonings: Covid-19’S Impact On Women Artists In New York And The Art Market During A Time Of Crisis, Elizabeth Glynn

MA in Art Business Dissertations

This dissertation investigates the impact of COVID-19 on women artists in New York City, emphasizing the existential challenges they faced and their responses within the art market. Through qualitative interviews, this research reveals how the pandemic catalyzed critical introspection, prompting artists to reevaluate their identities and creative practices. Despite systemic barriers to visibility and recognition, women artists exhibited resilience and adaptability, leveraging digital platforms to foster community engagement and expand their reach. This study dives deeper into the representation and support of women in the art sector, highlighting the interconnectedness of existentialism, creativity, and the evolving art market.

The Placenta & Covid-19: Histological Changes & Clinical Implications, Melissa F. Paul, Allyson J. Zadlo Sensor

All Electronic Theses and Dissertations

Introduction: The COVID-19 pandemic presented the medical community with complex and novel challenges, not the least of which is how to optimize prenatal and postnatal care for pregnant individuals who have been infected. At present, seven years have elapsed, and despite definitive research demonstrating adverse outcomes associated with placental changes, no professional consensus has been reached.
Methods: This integrative review includes studies involving pregnant individuals with confirmed SARS-CoV-2 infection, who recovered during the same pregnancy, and their infants. An examination of the data available reveals a triad of placental pathologies (chronic histiocytic intervillositis, perivillous fibrin deposition, and trophoblast necrosis) that …

Testing The Governance Premium: Board Gender Diversity And Crisis-Period Returns During The Pandemic, Rhea Kulkarni

CMC Senior Theses

This paper examines whether board gender diversity predicts cumulative abnormal returns for S&P 1500 firms during the COVID-19 pandemic. Motivated by prior evidence linking board gender diversity to crisis-period stock performance and the broader question of whether governance quality is priced during periods of acute market stress, this study estimates cumulative abnormal returns across three economically distinct event windows covering the crash, recovery, and post-recovery periods using the Carhart (1997) four-factor model to test whether board composition translated into divergent outcomes across firms. The results fail to find evidence that board gender diversity predicts cumulative abnormal returns across any of …

Bayesian Reanalysis Of Early Remdesivir For The Treatment Of Covid-19 In Outpatients With High Risk Of Progression To Severe Disease, Mazin Abdelghany, Fang Yu, Stephen I. Rennard, Yeongjin Gwon

Journal Articles: Pulmonary & Critical Care Med

BACKGROUND: Though Bayesian methods are flexible, intuitive, and readily incorporated into clinical decision-making, with particular utility when prior information is available, they remain underutilized in the analysis of clinical trials.

METHODS: In PINETREE, a Phase 3 randomized controlled trial (RCT) of remdesivir (RDV) for the treatment of outpatients with COVID-19 at high risk of severe disease, the primary outcome of COVID-19-related hospitalization or all-cause death was reanalyzed using a range of reference and data-driven priors. Posterior probability distributions were used to calculate the probability that the estimated hazard ratio (HR) was below a range of clinically meaningful specified thresholds and …

Institutional Retention And Graduation Outcomes Before And During Covid-19: A Comparison Of Online-Experienced And Online-Inexperienced Four-Year Institutions, Nicholas J. Finnessey

Theses and Dissertations

This study examined whether student success outcomes and their trajectories over time differed across higher education institutions before, during, and after the COVID-19 pandemic based on prior experience with online education. Guided by Astin’s (1993) Input-Environment-Output (I-E-O) framework, pre-pandemic participation in online coursework was conceptualized as an institutional-level environmental condition. A quantitative, causal-comparative research design was employed, using secondary data from the Integrated Postsecondary Education Data System (IPEDS), to examine longitudinal differences in institutional retention and graduation rates across institutions classified by their pre-pandemic participation in online education. The sample included 528 Title IV-eligible, degree-granting, four-year institutions observed across five …

Wastewater Surveillance For Sars-Cov-2 In Rural Kentucky, 2021–2023, James W. Keck, Reuben Adatorwovor, Ann Noble, Savannah Tucker, William Strike, Soroosh Torabi, Mohammad Dehghan Banadaki, Blazan Mijatovic, Steven K. Roggenkamp, Donna Mcneil, Lindell Ormsbee, Scott M. Berry

Family and Community Medicine Faculty Publications

Wastewater testing for SARS-CoV-2 provided useful public health information during the COVID-19 pandemic yet was underutilized in rural communities. We addressed this gap by implementing wastewater surveillance and assessing its performance in 10 communities in Eastern Kentucky. We collected wastewater samples 1–2 times weekly at 10 wastewater treatment plants (WWTPs) from May 2021 until April 2023 and measured SARS-CoV-2 RNA concentrations using polymerase chain reaction testing. We calculated time-lagged correlations between wastewater concentrations and county-level reported COVID-19 cases by site. We developed a generalized linear model to estimate COVID-19 incidence from wastewater SARS-CoV-2 concentrations. The 10 participating WWTPs served 2430 …

An Unusual Case Of Genetic Dilated Cardiomyopathy Unmasked By Covid-19 Infection, Greeshma Molugu, Daniel Mcmahan, Seline Haci, Giridhar Mundluru, Machaiah Madhrira

North Texas GME Research Forum 2026

Introduction: Titin (TTN) mutations are a well-known cause of dilated cardiomyopathy (DCM), occurring in approximately 25% of familial cases of idiopathic DCM and 18% of sporadic cases. Recognition and referral for genetic testing remains underutilized but has important prognostication and helps the patient better understand the disease transmission. This case report stresses the importance of a complete evaluation for genetic causes of DCM.

Case Presentation: A 21-year-old male who was adopted as an infant was hospitalized with COVID-19 infection and diagnosed with non-ischemic cardiomyopathy with an initial left ventricular ejection fraction (EF) of 10%. He was assumed to have DCM …

How Did Covid-19 Affect Volunteer And Donor Management For Human Services Agencies? What Are The Lessons For Future Response?, Nina Yon

Graduate Studies Theses and Dissertations 2026

The COVID-19 pandemic created unprecedented challenges for human services agencies, disrupting the interdependent systems of volunteer engagement and donor support essential to nonprofit sustainability. This study integrates insights from literature, theory, and empirical analysis to examine how nonprofit organizations adapted their volunteer and donor management strategies during this prolonged crisis. Drawing on Contingency Theory and Resource Dependence Theory (RDT), the research explores how organizational structures and strategies evolved in response to shifting environmental conditions, health mandates, and resource constraints. Using a multiple-case qualitative design, data was collected from semi-structured interviews with 20 leaders representing five Central Florida human services agencies, …

Does Working From Home Impact Audit Quality? Evidence From Non-Pharmaceutical Interventions During Covid-19, Monika Causholli, Sung-Yuan Mark Cheng, Nargess Golshan

Economics Faculty Publications

Catalyzed by the COVID-19 pandemic, many audit firms announced large-scale plans to adopt work-from-home (WFH) policies. It is unclear how this arrangement would affect audit quality. We exploit county-level non-pharmaceutical interventions, such as shelter-in-place orders and lockdowns, that exogenously increased local auditors’ WFH practices. We use a difference-in-differences research design to compare audit engagements that were affected by these policies to those that were not, including those within the same office. We find that WFH is associated with higher audit quality measured by discretionary accruals and going-concern opinions. We also find some evidence that these results are stronger for clients …

Adaptación De Los Docentes A Las Tecnologías En Educación A Distancia En Tiempos Del Covid-19, Kristy Rivera Crespo

Theses and Dissertations

El objetivo de este estudio fue examinar el nivel de conocimiento, el papel del apoyo institucional y el grado de satisfacción de los docentes de enfermería ante la integración de las tecnologías de la información y la comunicación (TIC) en la educación a distancia durante la pandemia del COVID-19, en una universidad ubicada en la región oeste de Puerto Rico.

Las preguntas de investigación se centraron en: (a) determinar el nivel de conocimiento que poseen los docentes sobre las TIC y las plataformas virtuales; (b) analizar el papel de la institución universitaria en el proceso de adopción y desarrollo de …

Uso De La Modalidad E-Learning En El Tema Del Aprendizaje Psicomotor En Tiempos De Covid-19, José A. Ghigliotti Acevedo

Theses and Dissertations

El propósito de este estudio fue analizar si la modalidad e-learning influyó en la satisfacción de los docentes de educación física del Departamento de Educación de Puerto Rico (DEPR) que habían recibido formación a distancia. Asimismo, se examinó el impacto del e-learning en el aprendizaje de habilidades psicomotoras pasada la crisis de la pandemia de COVID-19.

El marco conceptual se fundamentó en la Teoría del Conectivismo de Siemens (2004) y la Teoría de Satisfacción e Insatisfacción de Herzberg (1959). El estudio siguió un diseño cuantitativo, descriptivo y transeccional. La muestra estuvo conformada por 54 docentes de educación física del nivel …