Digital Commons Network^™

Endothelial Cell Contributions To Covid-19, Alexandra E. Oxford, Fabio Halla, Evan B. Robertson, Brad E. Morrison

Biology Faculty Publications and Presentations

Understanding of the clinical, histological and molecular features of the novel coronavirus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)) has remained elusive. Coronavirus disease 2019 (COVID-19) caused by this virus has unusual clinical presentation with regard to other related coronaviruses. Recent reports suggest that SARS-CoV-2, unlike other related viruses, infects and replicates within endothelial cells, which may explain a significant portion of the observed clinical pathology. Likewise, mounting evidence associates vascular and endothelial cell dysfunction with increased mortality. This review focuses on understanding how endothelial cell pathology is caused by SARS-CoV-2 at the molecular and cellular levels and how …

The Intersection Of An Epidemic And Pandemic: Smoking, Risk-Taking, And Covid-19, Allison H. Stranick

Student Publications

Electronic cigarette use has risen drastically in recent years among teens and young adults. Rates of conventional cigarette use have decreased, while rates of electronic cigarette use are on the rise. Knowledge and perceptions of the risks and benefits of conventional and electronic cigarettes greatly impacts adolescents and young adults’ decisions to use these products. Published literature explores the issues of social norms, intertemporal choice, present bias, prospect theory, and hyperbolic discounting as means to explain the way in which young populations perceive risk and risky behavior. Research suggests that children and young adults believe that e-cigarettes are safer, less …

Experiencing The Transition To Remote Teaching And Learning During The Covid-19 Pandemic, Chun-Hua Tsai, Guillermo Romera Rodriguez, Na Li, Jenay Robert, Alex Serpi, John Millar Carroll

Information Systems and Quantitative Analysis Faculty Publications

The sudden onset of the COVID-19 pandemic severely disrupted universities around the world. In the two weeks following a shelter–in-place order, all the actors of the educational system were forced to transition to remote education. This shift required a new reliance upon technologies that these individuals might never have adopted at all, often with significant difficulties. In this paper, we present a qualitative study on a university-wide survey dataset describing student and faculty experiences of abruptly transitioning to remote teaching and learning during the spring 2020 semester at the Pennsylvania State University. We performed an inductive thematic analysis to identify …

Ursinus Magazine, Fall 2020, Brock Blomberg, Ed Moorhouse, Jennifer Meininger Wolfe, Susanna A. Throop, Morgana Olbrich, Tiffini Eckenrod, Matthew Furgele, Logan Mazullo, Andrew Mcswiggan

Ursinus Magazine, 1995–Present

Scholar selected for nationally recognized SEED project • Ursinus rallies around Class of 2020 • Researching partisan news coverage of COVID-19 • Ursinus faculty and alumna collaborate on breast cancer study • These Bears stand out • Getting to know: Lauren Finnegan • Office space: A spectacle of storytelling • Bears on the front line • Tracing COVID-19's global course • Defending the den • Class notes • Births • Weddings • Deaths • In memoriam • Burning question: What can historical pandemics teach us about COVID-19?

Grace Hughes: 1918 & 2020 Pandemic Poster, Grace Erin Hughes

COVID-19 Graphic Design: Posters

• Mixed-media digital collage
• 18 inches wide, 24 inches high

Yamilet Perez Aragon: 1918 & 2020 Pandemic Poster, Yamilet Perez Aragon

COVID-19 Graphic Design: Posters

• Mixed-media digital collage
• 18 x 24 inches, vertical

Devan Moses: 1918 & 2020 Pandemic Poster, Devan Moses

COVID-19 Graphic Design: Posters

• Mixed-media digital collage
• 18 inches wide, 24 inches high

Brooke Baker: 1918 & 2020 Pandemic Poster, Brooke Baker

COVID-19 Graphic Design: Posters

• Mixed-media digital collage
• 18 inches wide, 24 inches high

Noah Gangloff: 1918 & 2020 Pandemic Poster, Noah Gangloff

COVID-19 Graphic Design: Posters

• Mixed-media digital collage
• 18 inches wide, 24 inches high

Assessment Of Lockdown Effect In Some States And Overall India: A Predictive Mathematical Study On Covid-19 Outbreak, Tridip Sardar, Sk Shahid Nadim, Sourav Rana, Joydev Chattopadhyay

Journal Articles

In the absence of neither an effective treatment or vaccine and with an incomplete understanding of the epidemiological cycle, Govt. has implemented a nationwide lockdown to reduce COVID-19 transmission in India. To study the effect of social distancing measure, we considered a new mathematical model on COVID-19 that incorporates lockdown effect. By validating our model to the data on notified cases from five different states and overall India, we estimated several epidemiologically important parameters as well as the basic reproduction number (R0). Combining the mechanistic mathematical model with different statistical forecast models, we projected notified cases in the six locations …

Lynn - 2020 Annual Edition: Year Of Resilience, Lynn University

Lynn Magazine / LYNN

The 2020 LYNN Magazine is the Office of Marketing and Communication's first-ever all-digital publication.

Read the digitally archived version of the 2020 LYNN magazine here.

2020 Fall - Clihhr Newsletter, Cardozo Law Institute In Holocaust And Human Rights (Clihhr)

CLIHHR Newsletters

This Fall 2020 issue of the CLIHHR Newsletter documents the Institute’s legal advocacy and programming during the COVID-19 pandemic and a period of heightened political and human rights challenges. It features litigation challenging U.S. sanctions against the International Criminal Court, amicus advocacy on Holocaust restitution, clinic efforts supporting Indigenous communities in Brazil, strategic planning on housing and health rights, student and alumni achievements, and virtual public events on genocide prevention, citizenship, and international justice. The newsletter reflects CLIHHR’s continued commitment to accountability, human rights protection, and survivor-centered advocacy.

Implications Of Covid-19 In High Burden Countries For Hiv/Tb: A Systematic Review Of Evidence, Jacques L. Tamuzi, Birhanu T. Ayele, Constance Shumba, Olatunji O. Adetokunboh, Jeannine Uwimana-Nicol, Zelalem T. Haile, Joseph Inugu, Peter S. Nyasulu

School of Nursing & Midwifery, East Africa

Background: The triple burden of COVID-19, tuberculosis and human immunodeficiency virus is one of the major global health challenges of the twenty-first century. In high burden HIV/TB countries, the spread of COVID-19 among people living with HIV is a well-founded concern. A thorough understanding of HIV/TB and COVID-19 pandemics is important as the three diseases interact. This may clarify HIV/TB/COVID-19 as a newly related field. However, several gaps remain in the knowledge of the burden of COVID-19 on patients with TB and HIV. This study was conducted to review different studies on SARS-CoV, MERS-CoV or COVID-19 associated with HIV/TB co-infection …

Simulating Covid-19 In A University Environment, P. T. Gressman, Jennifer R. Peck

Economics Faculty Works

Residential colleges and universities face unique challenges in providing in-person instruction during the COVID-19 pandemic. Administrators are currently faced with decisions about whether to open during the pandemic and what modifications of their normal operations might be necessary to protect students, faculty and staff. There is little information, however, on what measures are likely to be most effective and whether existing interventions could contain the spread of an outbreak on campus. We develop a full-scale stochastic agent-based model to determine whether in-person instruction could safely continue during the pandemic and evaluate the necessity of various interventions. Simulation results indicate that …

Effect Of Covid-19 Pandemic On Mechanical Thrombectomy For Acute Ischemic Stroke Treatment In United States, Adnan Qureshi, Farhan Siddiq, Brandi R. French, Camilo R. Gomez, Vishal Jani, Ameer E. Hassan, M.Fareed K. Suri

School of Medicine Publications

There is accumulating data suggesting that the ischemic stroke may be increased in patients with corona virus disease 2019 (COVID-19) due to hyper coagulopathy. An increase in acute ischemic stroke patients who require mechanical thrombectomy is to be expected particularly in regions with high rates of COVID-19.

Withania Somnifera As A Potential Future Drug Molecule For Covid-19, Vivek K. Kashyap, Anupam Dhasmana, Murali M. Yallapu, Subhash C. Chauhan, Meena Jaggi

School of Medicine Publications

COVID-19 is an infection disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a mild to severe respiratory illness which has caused significant disruption to normal life over the past few months, nearly bringing parts of the world to a halt. As of 26 August 2020, more than 24 million COVID-19 infections have been reported and 821,000 deaths are associated with this disease [1]. According to the WHO (Geneva, Switzerland) and the US CDC (MD, USA), the clinical manifestation of COVID-19 is the presence of fever or chills, sore throat, dry cough, fatigue, muscle/body aches, headache, loss …

Role Of Comorbidities Like Diabetes On Severe Acute Respiratory Syndrome Coronavirus-2: A Review, Subham Das, Anu K.R., Sumit Raosaheb Birangal, Ajinkya Nitin Nikam

Open Access archive

Pandemic coronavirus disease-2019, commonly known as COVID-19 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious disease with a high mortality rate. Various comorbidities and their associated symptoms accompany SARS-CoV-2 infection. Among the various comorbidities like hypertension, cardiovascular disease and chronic obstructive pulmonary disease, diabetes considered as one of the critical comorbidity, which could affect the survival of infected patients. The severity of COVID-19 disease intensifies in patients with elevated glucose level probably via amplified pro-inflammatory cytokine response, poor innate immunity and downregulated angiotensin-converting enzyme 2. Thus, the use of ACE inhibitors or angiotensin receptor blockers could …

Partially Reprapable Automated Open Source Bag Valve Mask-Based Ventilator, Aliaksei Petsiuk, Nagendra G. Tanikella, Samantha Dertinger, Adam Pringle, Shane Oberloier, Joshua M. Pearce

Michigan Tech Publications, Part 1

This study describes the development of a simple and easy-to-build portable automated bag valve mask (BVM) compression system, which, during acute shortages and supply chain disruptions can serve as a temporary emergency ventilator. The resuscitation system is based on the Arduino controller with a real-time operating system installed on a largely RepRap 3-D printable parametric component-based structure. The cost of the materials for the system is under $170, which makes it affordable for replication by makers around the world. The device provides a controlled breathing mode with tidal volumes from 100 to 800 mL, breathing rates from 5 to 40 …

Innovation In Medical School Teaching During Covid-19, Mariam Akhtar

Faculty and Staff Publications

No abstract provided.

Pandemic Profiles: Diving In With Julie Cutler, Emiliano Virgen Gonzalez

COVID-19 @ Whittier (full list of items)

Cutler is a Utah native who is meant to be attending Whittier College, in Whittier California. COVID-19, however, has recently made her life difficult, cutting her off from her second family in California. Although this is a big issue, it’s not the first serious complication she has faced, though you wouldn’t know it from her outgoing and relaxed personality.

Mediation: The New Normal?, Nadja Alexander

Research Collection Yong Pung How School Of Law

Imagine a tightrope walker, walking along a tightrope, holding a long, light rod. To help her balance, the performing artist continually moves the rod, changing the angle of the rod to maintain a constant – her balance in space. If she were to hold the rod in a fixed position, what would happen? She would fall off. In other words, the variation of the rod has the function of maintaining the deeper continuity which enables the artist to make it to the other end, alive. In this essay, the tightrope walker offers a metaphor for dispute resolution systems. In order …

Retrospective Study Examining Obesity Hypoventilation Syndrome In Covid+ Patients, Lily Chen, Areeb Masood, Ayman Khaddam, Alyssa Chen, Ildiko Lingvay, Henry Kwang

MEDI 9331 Scholarly Activities Clinical Years

Purpose: Coronavirus disease 2019 (COVID-19) has affected millions of people all over the world with worse proven outcomes in those with certain comorbid conditions, such as diabetes, cardiovascular disease, and pulmonary complications. The Rio Grande Valley located in South Texas with a largely Hispanic population has been hit especially hard during this pandemic with over 3,200 virus-related deaths. This region’s high population of diabetic and obese patients is likely correlated with the especially high mortality rate. While it is understood the impact that obesity has on worsening health outcomes, further research is needed to better understand whether more adverse COVID-19 …

America’S Moment: Investing In Positive Youth Development To Transform Youth And Society, Mary Arnold

Journal of Youth Development

As the COVID-19 pandemic wears on, America’s youth are suffering in unprecedented ways as their journey to adulthood is interrupted by multiple societal effects. This thought leader piece explores the power of positive youth development in a time of national crisis. The paper outlines the effects of COVID-19 on youths’ mental health, educational engagement, and workforce opportunities, all of which have been profoundly affected by the pandemic. The paper makes the case for increasing investment in positive youth development programs and people and highlights key areas where such programs can help support and transform youth, and in-turn society writ large. …

Maternal And Newborn Care During The Covid-19 Pandemic In Kenya: Re-Contextualising The Community Midwifery Model, Rachel Kimani, Rose Maina, Constance Shumba, Sheila Shaibu

School of Nursing & Midwifery, East Africa

Peripartum deaths remain significantly high in low- and middle-income countries, including Kenya. The COVID-19 pandemic has disrupted essential services, which could lead to an increase in maternal and neonatal mortality and morbidity. Furthermore, the lockdowns, curfews, and increased risk for contracting COVID-19 may affect how women access health facilities. SARS-CoV-2 is a novel coronavirus that requires a community-centred response, not just hospital-based interventions. In this prolonged health crisis, pregnant women deserve a safe and humanised birth that prioritises the physical and emotional safety of the mother and the baby. There is an urgent need for innovative strategies to prevent the …

Covid-19 And The Case For Global Development, Johan A. Oldekop, Rory Horner, David Hulme, Roshan Adhikari, Bina Agarwal, Matthew Alford, Oliver Bakewell, Nicola Banks, Stephanie Barrientos, Tanja Bastia, Anthony J. Bebbington, Upasak Das, Ralitza Dimova, Richard Duncombe, Charis Enns, David Fielding, Christopher Foster, Timothy Foster, Tomas Frederiksen, Ping Gao, Tom Gillespie, Richard Heeks, Sam Hickey, Martin Hess, Nicholas Jepson, Ambarish Karamchedu, Uma Kothari, Aarti Krishnan, Tom Lavers, Aminu Mamman, Diana Mitlin, Negar Monazam Tabrizi

Geography

COVID-19 accentuates the case for a global, rather than an international, development paradigm. The novel disease is a prime example of a development challenge for all countries, through the failure of public health as a global public good. The COVID-19 pandemic has highlighted the falsity of any assumption that the global North has all the expertise and solutions to tackle global challenges, and has further highlighted the need for multi-directional learning and transformation in all countries towards a more sustainable and equitable world. We illustrate our argument for a global development paradigm by examining the implications of the COVID-19 pandemic …

The Rising Costs Of Hospital Pharmaceutical Shortages And The Impact On Patient Care: Exploring The Use Of Predictive Analytics In New York Area Hospitals, Leticia Laura Currin

Doctoral Dissertations and Projects

This qualitative case study examined the rising cost of hospital pharmaceutical shortages and the impact on patient care. This study also explored the use of predictive analytics to reduce costs and improve patient care efficiency. Increased health-care spending is partially due to prescription medication prices. Management of hospital drug procurement affects patient health, quality care, and hospital budgets, while risk management needs to minimize possible medication shortages. For patients to get the drugs that they need, pharmacists need to have resources at their fingertips to obtain a deep insight into the knowledge of drugs through the supply chain. The research …

Breaking State-Centric Shackles In The Who: Taiwan As A Catalyst For A New Global Health Order, Ching-Fu Lin, Han-Wei Liu, Chien-Huei Wu

Research Collection Yong Pung How School Of Law

After World War II, states established World Health Organization (WHO), recognizing that “the health of all peoples is fundamental to the attainment of peace and security.” This aspiration, embedded in GlobalHealth governance, introduces a paradox vis-à-vis the WHO’s state-centric institutional design. Though Taiwan alerted the WHO to potential human-to-human transmission in the early stage of the pandemic, its participation in the WHO remains limited, contrasting the WHO’s goal of health for all peoples sharply against its outdated emphasis on statehood and power politics.This Essay critically assesses how and why state-centric international health governance neither delivers its goal to “promote and …

How Many Americans Have Lost Jobs With Employer Health Coverage During The Pandemic?, Paul Fronstin, Stephen A. Woodbury

External Papers and Reports

ISSUE: During the COVID-19 pandemic, most states issued lockdown orders that closed many workplaces. The ensuing job losses may have left millions of workers without employer health coverage.

GOAL: To estimate how many workers lost jobs that came with employer-sponsored insurance (ESI) — by industry, age, and gender — during the pandemic.

METHODS: Health insurance coverage data were used to generate the proportion of workers with ESI, by various characteristics. Data on unemployment benefit recipients were used to generate the proportion of workers who lost jobs because of the pandemic. We apply the proportion of workers with ESI to the …

Social Determinants Of Health-Related Needs During Covid-19 Among Low-Income Households With Children, Shreela V Sharma, Ru-Jye Chuang, Melinda Rushing, Brittni Naylor, Nalini Ranjit, Mike Pomeroy, Christine Markham

Faculty, Staff and Student Publications

INTRODUCTION: Little is known about the social needs of low-income households with children during the coronavirus-2019 (COVID-19) pandemic. Our objective was to conduct a cross-sectional quantitative and qualitative descriptive analysis of a rapid-response survey among low-income households with children on social needs, COVID-19-related concerns, and diet-related behaviors.

METHODS: We distributed an electronic survey in April 2020 to 16,435 families in 4 geographic areas, and 1,048 responded. The survey asked families enrolled in a coordinated school-based nutrition program about their social needs, COVID-19-related concerns, food insecurity, and diet-related behaviors during the pandemic. An open-ended question asked about their greatest concern. We …

Reinfection After Sars-Cov-2 Infection: A Looming Concern, Akshay Kumar, Nimisha Shiwalkar, Juber Dastagir Shaikh, Roopvir Kaur, Ana Francesca Vommaro Leite, Purnadeo Persaud, Asim Kichloo, Alfonso J. Rodríguez-Morales, Ranjit Sah

Student Publications

Many unanswered questions remain about COVID-19 infection caused by SARS-CoV-2 coronavirus. One such looming concern is the possibility of reinfection of recovered cases. We conducted a literature review on various aspects of this possibility, including the case presentations of relapsed/re-infected patients, the immune response of production of neutralizing antibodies, immunity in response to coronavirus during SARS-CoV2 and MERS, possibility of false-positive results of real-time polymerase chain reaction. We concluded that further studies are required to establish whether relapse or reinfection is possible firmly. However, these possibilities point towards the needs of change in the protocol of isolation, quarantine, and discharge. …