Digital Commons Network^™

Postacute Sequelae Of Sars-Cov-2 Infection In The Pre-Delta, Delta, And Omicron Eras, Yan Xie, Taeyoung Choi, Ziyad Al-Aly

2020-Current year OA Pubs

BACKGROUND: Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) can affect many organ systems. However, temporal changes during the coronavirus disease 2019 (Covid-19) pandemic, including the evolution of SARS-CoV-2, may have affected the risk and burden of PASC. Whether the risk and burden of PASC have changed over the course of the pandemic is unclear.

METHODS: We used health records of the Department of Veterans Affairs to build a study population of 441,583 veterans with SARS-CoV-2 infection between March 1, 2020, and January 31, 2022, and 4,748,504 noninfected contemporaneous controls. We estimated the cumulative incidence of …

Perspectives On Telemedicine Across Urban, Rural And Remote Areas In The Philippines During The Covid-19 Pandemic, Noleen Fabian, Regine Ynez De Mesa, Carol Tan-Lim, Gillian Sandigan, Johanna Lopez, Arianna Maever Loreche, Leonila Dans, Zharie Benzon, Herbert Zabala, Josephine Sanchez, Nanette Sundiang, Mia Rey, Antonio Dans

Ateneo School of Medicine and Public Health Publications

Objectives

This study explored attitudes, subjective norms, and perceived behavioural control of participants across urban, rural and remote settings and examined intention-to-use telemedicine (defined in this study as remote patient-clinician consultations) during the COVID-19 pandemic.

Methods

This is a cross-sectional study. 12 focus group discussions were conducted with 60 diverse telemedicine user and non-user participants across 3 study settings. Analysis of responses was done to understand the attitudes, norms and perceived behavioural control of participants. This explored the relationship between the aforementioned factors and intention to use.

Results

Both users and non-users of telemedicine relayed that the benefits of telemedicine …

Disparities And Protective Factors In Pandemic-Related Mental Health Outcomes: A Louisiana-Based Study, Ariane L. Rung, Evrim Oral, Tyler Prusisz, Edward S. Peters

School of Public Health Faculty Publications

Introduction: The COVID-19 pandemic has had a wide-ranging impact on mental health. Diverse populations experienced the pandemic differently, highlighting pre-existing inequalities and creating new challenges in recovery. Understanding the effects across diverse populations and identifying protective factors is crucial for guiding future pandemic preparedness. The objectives of this study were to (1) describe the specific COVID-19-related impacts associated with general well-being, (2) identify protective factors associated with better mental health outcomes, and (3) assess racial disparities in pandemic impact and protective factors. Methods: A cross-sectional survey of Louisiana residents was conducted in summer 2020, yielding a sample of 986 Black …

The Impact Of Covid-19 On Mental Health- A Comparison Between Gender & Race, Taliyah Quinn

Theses and Dissertations

My study will focus on the rise of mental health toward the African American, Latinx and Asian Americans communities due to the COVID-19 pandemic. The spread of the virus, the high percentage rate of infections among minorities, isolation, quarantining and socio economic disadvantages played a major role in the increase of mental disparities.

E-Learning Strategies Implemented By Instructors For Individuals With Hearing Impairment, Sherin Joy, Archana Gundmi

Open Access archive

The current study aims at exploring the strategies used by instructors to deal with e-learning of individuals with hearing impairment and identifying barriers encountered by instructors of individuals with hearing impairment through a telephonic interview. A set of validated probes was created, and a semi structured interview was conducted with 12 instructors who teach individuals with hearing impairment. The obtained data was subjected to inductive content analysis. Two major themes emerged from the data; challenges encountered by instructors and strategies adopted by instructors. Several subthemes and codes were grouped under each theme. Overall, the study indicated the need for extensive …

Evolving Community Preparedness: Analysis Of United States Pandemic Health Disaster Readiness, Jessy Rugeyo

Theses and Dissertations

The COVID-19 pandemic has shown substantial gaps in counties' preparedness and response capacity across the United States. This study analyzes the relationship between county-level pandemic preparedness and confirmed COVID-19 cases using secondary data from the FEMA's National Household Survey (NHS) and county-level COVID-19 data from the CDC. The data show a negative relationship between preparedness levels and COVID-19 positive rates, highlighting the necessity of proactive readiness measures. Individual risk assessment, motivation for preparedness, and socioeconomic variables have a major influence on confirmed cases. Higher levels of education, income, and preparedness are associated with lower positive rates, emphasizing the importance of …

Economic Development In Legacy Cities: Current And Emerging Challenges And Opportunities, Neil Reid, Sujata Shetty, Jane Adade

Midwest Social Sciences Journal

As manufacturing employment has declined in the traditional manufacturing regions over the past decades, many communities have experienced population loss and overall economic decline. Local economic development professionals have had to grapple with long-term structural changes in the economy as well as short-term jolts. To gain insights into the changing landscape of economic development, we interviewed economic development practitioners in Indiana, Michigan, Ohio, and Pennsylvania. The interviews focused on their perception of current and emerging challenges and opportunities with respect to economic development in their respective communities. Having identified the major challenges and opportunities, we asked them to articulate the …

Leveraging Machine Learning And Stochastic Programming To Address Vaccine Hesitancy In Public Health Resource Allocation, Hieu Trung Bui

Graduate Theses and Dissertations

Infectious disease outbreaks highlight the urgent need for effective strategies to distribute vaccines and allocate critical healthcare resources to contain the disease and reduce its negative impacts on the population. Managing these allocations is a significant challenge, especially in marginalized communities facing uncertainty in healthcare demand and logistical constraints. This dissertation addresses these challenges by investigating factors that influence dynamic changes in vaccine hesitancy (VH) and its implications for disease spread and healthcare resource demand. It develops optimization models for vaccine distribution and resource allocation under uncertainty, validated with data from the COVID-19 pandemic in the U.S. The first study …

A Community Health Worker Led Diabetes Self-Management Education Program: Reducing Patient And System Burden, Michael E Bowen, Carolyn Smith-Morris, Elizabeth M Vaughan

Faculty, Staff and Students Publications

Aims: Conduct a secondary analysis of the TIME (Telehealth-supported, Integrated Community Health Workers (CHWs), Medication access, diabetes Education) made simple trial (SIMPLE) to evaluate healthcare utilization and explore variables that may have influenced HbA1c.

Methods: Participants (N = 134 [67/group]) were low-income, uninsured Hispanics with or at risk for type 2 diabetes mellitus. We included in-person and telehealth clinician visits, other visits, missed visits, orders placed, and guideline-adherence (e.g., vaccinations, quarterly HbA1c for uncontrolled diabetes). Using multivariable models, we explored for associations between HbA1c changes and these measures.

Results: The control arm had higher missed visits rates (intervention: 45 %; …

Pediatric Mental Health Emergency Department Visits From 2017 To 2022: A Multicenter Study, David Ashby, Kamali L Bouvay, Susan J Duffy, James M Chamberlain, Sofia S Chaudhary, Nicolaus W Glomb, Jacqueline Grupp-Phelan, Maya Haasz, Erin P O'Donnell, Mohsen Saidinejad, Bashar S Shihabuddin, Leah Tzimenatos, Neil G Uspal, Joseph J Zorc, Lawrence J Cook, Elizabeth R Alpern

Faculty, Staff and Students Publications

Background: The COVID-19 pandemic adversely affected children's mental health (MH) and changed patterns of MH emergency department (ED) utilization. Our objective was to assess how pediatric MH ED visits during the COVID-19 pandemic differed from expected prepandemic trends.

Methods: We retrospectively studied MH ED visits by children 5 to < 18 years old at nine U.S. hospitals participating in the Pediatric Emergency Care Applied Research Network Registry from 2017 to 2022. We described visit length by time period: prepandemic (January 2017-February 2020), early pandemic (March 2020-December 2020), midpandemic (2021), and late pandemic (2022). We estimated expected visit rates from prepandemic data using multivariable Poisson regression models. We calculated rate ratios (RRs) of observed to expected visits per 30 days during each pandemic time period, overall and by sociodemographic and clinical characteristics.

Results: We identified 175,979 pediatric MH ED visits. Visit length exceeded 12 h for 7.3% prepandemic, 8.4% early pandemic, 15.0% midpandemic, and 19.2% late pandemic visits. During the early pandemic, observed visits per 30 days decreased relative to expected rates (RR 0.80, 95% confidence interval [CI] 0.78-0.84), were similar to expected …

Preeclampsia In The Context Of Covid-19: Mechanisms, Pathophysiology, And Clinical Outcomes, Guilherme M Nobrega, Brittany R Jones, Indira U Mysorekar, Maria Laura Costa

Center on Aging Staff Publications

The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to the global COVID-19 pandemic, significantly impacting the health of pregnant women. Obstetric populations, already vulnerable, face increased morbidity and mortality related to COVID-19, aggravated by preexisting comorbidities. Recent studies have shed light on the potential correlation between COVID-19 and preeclampsia (PE), a leading cause of maternal and perinatal morbidity worldwide, emphasizing the significance of exploring the relationship between these two conditions. Here, we review the pathophysiological similarities that PE shares with COVID-19, with a particular focus on severe COVID-19 cases and in PE-like syndrome cases related with …

Expanding A Behavioral View On Digital Health Access: Drivers And Strategies To Promote Equity, Maura M Kepper, Lauren A Fowler, Isabelle S Kusters, Jean W Davis, Manal Baqer, Sara Sagui-Henson, Yunyu Xiao, Adati Tarfa, Jean C Yi, Bryan Gibson, Kristin E Heron, Nicole M Alberts, Marissa Burgermaster, Veronica Ps Njie-Carr, Lisa M Klesges

Center for Medical Ethics and Health Policy Staff Publications

The potential and threat of digital tools to achieve health equity has been highlighted for over a decade, but the success of achieving equitable access to health technologies remains challenging. Our paper addresses renewed concerns regarding equity in digital health access that were deepened during the COVID-19 pandemic. Our viewpoint is that (1) digital health tools have the potential to improve health equity if equitable access is achieved, and (2) improving access and equity in digital health can be strengthened by considering behavioral science-based strategies embedded in all phases of tool development. Using behavioral, equity, and access frameworks allowed for …

E-Cigarette Use Reasons And Associated E-Cigarette Use Dependence Among College Students: A Longitudinal Examination

Faculty, Staff and Student Publications

Objective: Previous studies have established an understanding of reasons for e-cigarette use and associated e-cigarette use patterns such as use frequency, yet the critical extension to associated e-cigarette dependence outcome remains under-researched. This study used longitudinal data to examine whether the reasons for e-cigarette use predict a higher/lower level of e-cigarette dependence.

Methods: This study recruited college students who were current e-cigarette users from Fall 2019 to Fall 2020 (four semesters) at three public universities in the Midwest and South of the U.S. Those who participated for at least two semesters were included (N = 366). Data were collected using …

Increasing Incidence Of Streptococcus Anginosus Group Intracranial Infections Associated With Sinusitis, Otitis Media, And Mastoiditis In Children, Amy Dimachkieh, Hossaena Ayele, Blake M Hanson, Sheldon L Kaplan, Jesus G Vallejo, J Chase Mcneil

Faculty, Staff and Student Publications

BACKGROUND: The Streptococcus anginosus group (SAG) pathogens have the potential to cause head and neck space infections, including intracranial abscesses. Several centers noted an increase in intracranial abscesses in children during the SARS-CoV-2 pandemic, prompting a Centers for Disease Control and Prevention health alert in May 2022. We examined the epidemiology of pediatric intracranial abscesses at a tertiary care center with a focus on SAG pre- and post-pandemic.

METHODS: Cases of intracranial abscesses of any microbiologic etiology admitted from January 2011 to December 2022 were identified using International Classification of Diseases 10 codes. Subjects were cross-referenced with culture results from …

Challenges In Lncrna Biology: Views And Opinions, Ekaterina G Derevyanchuk, Tatiana P Shkurat, Jeffrey A Loeb, Ivan Martinez, Leonard Lipovich

Faculty, Staff and Student Publications

This is a mini-review capturing the views and opinions of selected participants at the 2021 IEEE BIBM 3rd Annual LncRNA Workshop, held in Dubai, UAE. The views and opinions are expressed on five broad themes related to problems in lncRNA, namely, challenges in the computational analysis of lncRNAs, lncRNAs and cancer, lncRNAs in sports, lncRNAs and COVID-19, and lncRNAs in human brain activity.

Im/Mobilities During The Covid-19 Pandemic: Perspectives From International Graduate Students Studying In The Southern United States, Christina W. Yao, Kaitlyn Hall, Simone Gause, Leslie Jo Shelton

Educational Sciences and Organizations

The background of this study is situated within the COVID-19 pandemic as an acute challenge with chronic issues that international graduate students have faced continuously. With the pandemic serving as a critical incident, we highlight the political, systemic, and personal fragilities of international graduate students studying in the southern United States. The methods for our study were informed by a narrative inquiry approach combined with a systematic literature review to connect with the conceptual framework of Avison and Turner’s chronic strains and Robertson’s conception of timescales. The findings highlight three broad themes: shifting immigration policies and travel uncertainty, institutional responses, …

Expanding A Behavioral View On Digital Health Access: Drivers And Strategies To Promote Equity, Maura M Kepper, Lauren A Fowler, Isabelle S Kusters, Jean W Davis, Manal Baqer, Sara Sagui-Henson, Yunyu Xiao, Adati Tarfa, Jean C Yi, Bryan Gibson, Kristin E Heron, Nicole M Alberts, Marissa Burgermaster, Veronica Ps Njie-Carr, Lisa M Klesges

2020-Current year OA Pubs

The potential and threat of digital tools to achieve health equity has been highlighted for over a decade, but the success of achieving equitable access to health technologies remains challenging. Our paper addresses renewed concerns regarding equity in digital health access that were deepened during the COVID-19 pandemic. Our viewpoint is that (1) digital health tools have the potential to improve health equity if equitable access is achieved, and (2) improving access and equity in digital health can be strengthened by considering behavioral science-based strategies embedded in all phases of tool development. Using behavioral, equity, and access frameworks allowed for …

A Mixed Methods Exploration Of Young Women's Agency And Mental Health During Covid-19 In Low-Income Communities In Mumbai, India, Rinchen O Bhutia, Rajendra Singh, Poornima Nair, Rajesh Vedanthan, Sten H Vermund, Shubhada Maitra

Faculty, Staff and Student Publications

Introduction: Adolescent girls and young women (AGYW) in India face additional health inequities compared to their male peers, as gender norms constrain agency for prevention and self-care. The onset of the COVID-19 pandemic and associated lockdowns deepened health inequities and often worsened mental health, but the impacts on agency are unclear. This exploratory sequential mixed methods paper examined mental health and COVID-19 elements that exacerbated or mitigated adverse consequences for AGYW in low-income communities in Mumbai.

Methods: We conducted semi-structured interviews with AGYW (aged 15-25 years; N = 60) and adults (parents, healthcare providers, community-based organization representative; N = 30). …

The Correlation Of Age With Thrombocytes And D-Dimer Values In Covid-19 Patients At Hospital X In Jakarta, Indonesia, Nanik Prasetyoningsih, Ascobat Gani

Kesmas

Coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, spread globally, with research indicating that prognosis severity can be assessed by thrombocyte and D-dimer levels; while, patient age serves as a mortality predictor. This study aimed to analyze the relationship between age with thrombocytes and D-dimer in COVID-19 patients. This cross-sectional study used laboratory testing samples from 667 COVID-19 patients at Hospital X in Jakarta, Indonesia, collected from August 2020 until May 2021. The data was collected using cluster random sampling and analyzed using descriptive statistics and the Chi square test (95% CI). The results showed that age and thrombocytes positively …

Frailty Explains Variation In Emergency Department Use For Older Veterans During The Covid-19 Pandemic, Justine Seidenfeld, Karen M. Stechuchak, Valerie A. Smith, Catherine Stanwyck, Chelsea Perfect, Courtney Van Houtven, Susan Nicole Hastings

Journal of Geriatric Emergency Medicine

Background: Older adults were critically vulnerable to disruptions in health care during the COVID-19 pandemic, but it is not known if changes in ED utilization varied based on patient characteristics. Using a cohort of older Veterans, we examined changes in ED visit rates based on four characteristics of interest: age, race, area deprivation index, and frailty

Methods: Participants were aged ≥65, with ≥2 visits in primary or geriatric clinics between 02/02/2018-05/07/2019. An adjusted negative binomial regression model was constructed for each characteristic. We report mean counts of all ED visits by quarter for subgroups separately, and report rate …

The Association Between Prolonged Sars-Cov-2 Symptoms And Work Outcomes, Arjun K Venkatesh, Huihui Yu, Caitlin Malicki, Michael Gottlieb, Joann G Elmore, Mandy J Hill, Ahamed H Idris, Juan Carlos C Montoy, Kelli N O'Laughlin, Kristin L. Rising, Kari A Stephens, Erica S Spatz, Robert A Weinstein

Department of Emergency Medicine Faculty Papers

While the early effects of the COVID-19 pandemic on the United States labor market are well-established, less is known about the long-term impact of SARS-CoV-2 infection and Long COVID on employment. To address this gap, we analyzed self-reported data from a prospective, national cohort study to estimate the effects of SARS-CoV-2 symptoms at three months post-infection on missed workdays and return to work. The analysis included 2,939 adults in the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE) study who tested positive for their initial SARS-CoV-2 infection at the time of enrollment, were employed before the pandemic, and completed …

Impact Of Covid-19 On Dental Students’ Mental Health Status And Perception Of Sars-Cov-2 Vaccine, Man Hung, Nicole Hablitzel, Sharon Su, Samantha Melnitsky, Amir Mohajeri

Pacific Faculty Work

The COVID-19 pandemic disrupted dental education significantly, forcing adaptations in both didactic and clinical curricula. This study evaluates the impact of COVID-19 on dental students’ mental health and perceptions of the SARS-CoV-2 vaccine. An anonymous online survey was administered to dental students at Roseman University of Health Sciences, focusing on health experiences and vaccination perceptions. Results showed 56.8% of students were concerned about their emotional health, 82.1% felt stressed, and 60.6% felt depressed. About 81.9% received the vaccine, with 75.5% believing it effective, though only 55.3% supported mandatory vaccination. The pandemic negatively impacted students’ emotional health, indicating a need for …

The Impact Of The Covid-19 Pandemic On The Incidence Of Sexual Assaults And Victim Services, Jessica Hunter

Student Works

The Impact of the Covid-19 Pandemic on the Incidence of Sexual Assaults and Victim Services

Purpose: The purpose of this literature review is to discuss incidents/rates of sexual assaults (SA), access to or accessibility of SA victim services, and the utilization of SA services during the COVID-19 pandemic.

Background: In the U.S., 1 in 5 women experience rape or attempted rape, while 1 in 4 men experience some form of sexual violence in their lifetime. Additionally, SAs affect roughly one-third of the world's population, making SA a prominent problem worldwide.

Methods: Electronic searches in CINHAL and MEDLINE were performed using …

The Interplay Between Gender And Duration Of Hospitalization Modulates Psychiatric Symptom Severity In Subjects With Long Covid-19, Emanuela De Chiara, Antonio Maria D'Onofrio, Salvatore Lioniello, Giovanni Camardese, Delfina Janiri, Matteo Tosato, Francesco Landi, Gabriele Sani

Faculty, Staff and Students Publications

Long COVID-19 is characterized by ongoing symptoms or prolonged or long-term complications of SARS-CoV-2 contraction which persist beyond 4 weeks from the initial onset of symptoms. Gender and duration of hospitalization (DH) are key risk factors for developing long COVID-19 syndrome, but their impact and interplay need further study. This research involved 996 long COVID-19 patients, and we compared the levels of general psychopathology, depression, agitated depression, anxiety, and medication use between hospitalized and non-hospitalized males and females. In the hospitalized patients, multivariate regressions assessed the impact of gender, DH, and the interaction of these variables. The females had higher …

Teaching Staff Mathematics University: Catalyst Of The Emotional-Techno-Ontological Logic, Derling Jose Mendoza Velazco Dr, Magda Francisca Cejas Martínez Phd, Carmen Siavil Varguillas Carmona Phd, Mercedes Carolina Navarro Cejas Phd, Gina Silvana Venegas Álvarez M.Sc.

The Qualitative Report

The relevance of the study lies in the necessity to investigate the psycho-emotional state of teachers during the transition to remote teaching in universities and its impact on academic performance and emotional state of students. The aim of the research was to develop a theoretical approach to describe the emotional and techno-ontological logic of mathematics teachers during distance learning during the COVID-19 pandemic and the impact of their emotional state on the learning process. The study involved teachers and students from universities in Ecuador, both private and public. The study observed the behavior of teachers and students, analyzed the use …

A Comparative Analysis Of Sars-Cov-2 Variants Of Concern (Voc) Spike Proteins Interacting With Hace2 Enzyme, Jiawei Chen, Lingtao Chen, Heng Quan, Soongoo Lee, Kaniz Fatama Khan, Ying Xie, Qiaomu Li, Maria Valero, Zhiyu Dai, Yixin Xie

2020-Current year OA Pubs

In late 2019, the emergence of a novel coronavirus led to its identification as SARS-CoV-2, precipitating the onset of the COVID-19 pandemic. Many experimental and computational studies were performed on SARS-CoV-2 to understand its behavior and patterns. In this research, Molecular Dynamic (MD) simulation is utilized to compare the behaviors of SARS-CoV-2 and its Variants of Concern (VOC)-Alpha, Beta, Gamma, Delta, and Omicron-with the hACE2 protein. Protein structures from the Protein Data Bank (PDB) were aligned and trimmed for consistency using Chimera, focusing on the receptor-binding domain (RBD) responsible for ACE2 interaction. MD simulations were performed using Visual Molecular Dynamics …

Changes At The Heart: Adapting Eucharist In The Time Of Pandemic, Marjorie M. Snipes

Proceedings of the annual meeting of the Southern Anthropological Society

During the initial COVID-19 pandemic period of 2020-2021, social institutions worldwide faced stress in adapting to immediate needs, among them places of worship which faced challenges from the disruption of social gatherings, religious services, tithing, and the celebration of key rituals. While many churches suspended or postponed rituals such as weddings, funerals, and baptisms, the practice of Eucharist presented a unique challenge. This ethnographic research focuses on mainline Christian churches in a semi-urban town in the state of Georgia (U.S.). It examines the ways that the experience of shutdown and social isolation affected the practice of Eucharist in Catholic, Baptist, …

Career Women’S Experiences Of Marital Discord And Domestic Violence During The Covid-19 Pandemic In Indonesia, Siti Mas’Udah, Lutfi Apreliana Megasari, Evan Doran, Rustinsyah, Muhammad Saud, Bagong Suyanto, Erna Setijaningrum

Journal of International Women's Studies

Domestic violence is a serious social problem, and the number of domestic violence cases are increasing each year in Indonesia. This study aims to explore marital discord and types and triggers of domestic violence experienced by career women who worked from home during the COVID-19 pandemic (2020-2021). In this qualitative research, the researchers interviewed professional working women who experienced domestic violence perpetrated by their husbands in East Java. This study shows that marital discord escalated into domestic violence due to complications experienced when they were staying at home because of the lockdown. Daily engagement between husbands and wives had an …

Use Of Population-Weighted Density Index For Coronavirus Spread In The United States, Huseyin Yuce, Hannah Stauss, Adrienne Persad

Publications and Research

Background: Understanding how population density affected the transmission of COVID-19 is vitally important, since crowded cities were the epicenters for the disease. Since human contact was the main cause of the spread, population-weighted densities have been shown to be a better measure than conventional densities, since the variation in density across subareas matters more than the density in the total area. Objectives: This study investigates the impact of population-weighted density and other demographics on the rate of COVID-19 spread in the United States. Methods: The study considers population-weighted density and many other demographics. The population-weighted density index is the weighted …

Abstracts From The 2024 Health Care Systems Research Network (Hcsrn) Annual Conference, Milwaukee, Wisconsin, Health Care Systems Research Network

Journal of Patient-Centered Research and Reviews

The Health Care Systems Research Network (HCSRN) comprises 20 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate project findings, explore scientific collaborations, and share insights about population-based research practices that can measurably improve health and health care for all. The theme of this year’s conference was “Advancing high-quality, equitable research in the age of new health care technologies.” Abstracts presented at HCSRN 2024 are published in this issue supplement of the Journal of Patient-Centered Research and Reviews, the journal of record …