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Remote Hiring Innovation During The Covid-19 Pandemic, Melanie D. Jewkes, Jonathan J. Swinton, Shannon Cromwell, David G. Schramm, Naomi Brower Oct 2020

Remote Hiring Innovation During The Covid-19 Pandemic, Melanie D. Jewkes, Jonathan J. Swinton, Shannon Cromwell, David G. Schramm, Naomi Brower

Journal of Extension

Extension's in-person hiring processes have been complicated in 2020 by the COVID-19 pandemic. To prevent delays in hiring for three vacant county faculty positions, our search committee conducted remote interviews using a variety of innovative techniques, such as a live "we're hiring" webinar, an icebreaker session, and live and recorded candidate presentations. The results of our innovative efforts included a larger pool of applicants, relaxed web-based video interviews, and savings in time and expenses. These strategies could be considered as new and effective approaches and practices to hiring and interviewing in Extension as the pandemic continues and into the future.


Aaim Recommendations For The 2020-2021 Internal Medicine Residency Application Cycle In Response To The Covid-19 Pandemic, Katherine C Chretien, Jaya M Raj, Reeni A Abraham, Paul Aronowitz, Donna J Astiz, Shobhina G Chheda, Ernie L Esquivel, Maria M Garcia, Nadia Ismail, Susan Lane, Suzanne E Mclaughlin, Anne Pereira, Amy W Shaheen, Abby L Spencer, Kimberly M Tartaglia, Lisa L Willett Oct 2020

Aaim Recommendations For The 2020-2021 Internal Medicine Residency Application Cycle In Response To The Covid-19 Pandemic, Katherine C Chretien, Jaya M Raj, Reeni A Abraham, Paul Aronowitz, Donna J Astiz, Shobhina G Chheda, Ernie L Esquivel, Maria M Garcia, Nadia Ismail, Susan Lane, Suzanne E Mclaughlin, Anne Pereira, Amy W Shaheen, Abby L Spencer, Kimberly M Tartaglia, Lisa L Willett

Faculty, Staff and Students Publications

This statement was released in June 2020 by the Alliance for Academic Internal Medicine to provide guidance for the 2020-2021 residency application cycle in light of the COVID-19 pandemic. While many of the recommendations are specific to this cycle, others, such as the Department Summary Letter of Evaluation, are meant to be an enduring change to the internal medicine residency application process. AAIM realizes that some schools may not yet have the tools or resources to implement the template fully this cycle and look toward collaboration within the internal medicine education community to facilitate adoption in the cycles to come.


Gastrointestinal Symptoms In Patients With Covid-19, Mohammed Abbas, Rafik Elbeblawy, Islam Gadelmoula, Suvarna Rekha, Bettina Sinanova, Jose Bordon Sep 2020

Gastrointestinal Symptoms In Patients With Covid-19, Mohammed Abbas, Rafik Elbeblawy, Islam Gadelmoula, Suvarna Rekha, Bettina Sinanova, Jose Bordon

The University of Louisville Journal of Respiratory Infections

Introduction: Though coronavirus disease 2019 (COVID-19) is predominantly a respiratory illness, a growing number of studies reported gastrointestinal (GI) symptoms among these patients. We examined the incidence of GI symptoms in patients with COVID-19 and GI symptoms as the initial presentation of the disease.

Methods: We examined peer-reviewed studies in English of patients with COVID-19 that reported GI symptoms. We searched PubMed and Google Scholar for articles published up to June 30, 2020, by using the keywords ``COVID-19,'' ``Coronavirus,'' ``severe acute respiratory syndrome coronavirus 2,'', ``SARS-CoV-2,'' ``gastrointestinal tract,'' ``gastrointestinal diseases,'' and ``gastrointestinal symptoms and signs.'' Studies with fewer than 30 …


Covid-19 And The Black Death: Nutrition, Frailty, Inequity, And Mortality, Katherine D. Van Schaik, Sharon Dewitte Sep 2020

Covid-19 And The Black Death: Nutrition, Frailty, Inequity, And Mortality, Katherine D. Van Schaik, Sharon Dewitte

Faculty Publications

Introduction: COVID-19 has challenged governments, healthcare systems, and individuals, drawing attention to the limits of modern technology and the extent of social inequity. Such challenges have directed attention to historical epidemics as repositories of data that could contribute to effective public health strategies and prognostic modeling. In light of the well-established correlation between frailty and mortality from COVID-19, this paper investigates the relationship between frailty, inequity, and mortality in the setting of the Black Death of 1346 – 1353, in order to identify trends over time in populations at the greatest risk of mortality during pandemics.

Methods: A comparative review …


Cerebrovascular Events And Outcomes In Hospitalized Patients With Covid-19: The Svin Covid-19 Multinational Registry, James E. Siegler, Pere Cardona, Juan F. Arenillas, Blanca Talavera, Ana N. Guillen, Alba Chavarrıa-Miranda, Mercedes De Lera, Priyank Khandelwal, Ivo Bach, Ameer E. Hassan, Laurie Preston, Mary S. Patterson, Saif Bushnaq, Osama Zaidat Sep 2020

Cerebrovascular Events And Outcomes In Hospitalized Patients With Covid-19: The Svin Covid-19 Multinational Registry, James E. Siegler, Pere Cardona, Juan F. Arenillas, Blanca Talavera, Ana N. Guillen, Alba Chavarrıa-Miranda, Mercedes De Lera, Priyank Khandelwal, Ivo Bach, Ameer E. Hassan, Laurie Preston, Mary S. Patterson, Saif Bushnaq, Osama Zaidat

School of Medicine Publications

Background

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has been associated with a significant risk of thrombotic events in critically ill patients.

Aim

To summarize the findings of a multinational observational cohort of patients with SARS-CoV-2 and cerebrovascular disease.

Methods

Retrospective observational cohort of consecutive adults evaluated in the emergency department and/or admitted with coronavirus disease 2019 (COVID-19) across 31 hospitals in four countries (1 February 2020–16 June 2020). The primary outcome was the incidence rate of cerebrovascular events, inclusive of acute ischemic stroke, intracranial hemorrhages (ICH), and cortical vein and/or sinus thrombosis (CVST).

Results

Of the 14,483 patients with laboratory-confirmed SARS-CoV-2, …


Fixing Social Media: Toward A Democratic Digital Commons, Michael Kwet Sep 2020

Fixing Social Media: Toward A Democratic Digital Commons, Michael Kwet

Markets, Globalization & Development Review

In the past few years, big Social Media networks like Facebook, Twitter, and YouTube have received intense scrutiny from the intellectual classes. This article critiques the dominant strain of criticism, the neo-Brandeisian School of antitrust, for its narrow focus on “regulated competition” as an appropriate means to “fix social media”. This essay calls for a socialist alternative: a democratic social media commons based on free and open source technology, decentralization, and democratic socialist legal solutions. It reviews how existing solutions like the Fediverse and LibreSocial work, and how they may provide answers for a better way forward.


‘Coronated’ Consumption In The Viral Market, Soonkwan Hong Sep 2020

‘Coronated’ Consumption In The Viral Market, Soonkwan Hong

Markets, Globalization & Development Review

The universal exposure to the virus has disrupted institutions, redefined values, and reshaped systems, including the market. Idling, uncertainty, and liquidity encapsulate the ever-precarious individual lives and the reflexive socio-politico-cultural changes. These conditions and consequences nonetheless create paradoxical opportunities in the viral market. The new meaning of connectivity that promotes high-viscosity relationships and high-visibility identities will transform the market to better acknowledge and support humans and the new sociality.


How The Covid-19 Pandemic Is Challenging Consumption, Marine Cambefort Sep 2020

How The Covid-19 Pandemic Is Challenging Consumption, Marine Cambefort

Markets, Globalization & Development Review

COVID-19 has led consumers to question their consumption patterns. Although some management research has already highlighted consumption trends resulting from the virus outbreak, very few studies explore how the current pandemic challenges consumption. Three trends are identified: the downsizing of consumption, emergence of anti-globalization sentiments, and negative consumer reactions to the misconduct of brands/companies. First, the lockdown was an opportunity for people to test a simpler lifestyle by reducing their level of consumption, having realized that over-consumption does not make them happy and questioned its negative impact on the environment. Second, the pandemic may reinforce anti-globalization ideas, leading consumers to …


Rethink Everything 1: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik Sep 2020

Rethink Everything 1: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik

Markets, Globalization & Development Review

No abstract provided.


Endoscopic Removal Of Fractured 3d-Printed Nasopharyngeal Swabs From The Olfactory Cleft During Covid-19, Matthew Miller, Kristy Carlson, Jayme Dowdall, Christie Barnes, Sam Pate Sep 2020

Endoscopic Removal Of Fractured 3d-Printed Nasopharyngeal Swabs From The Olfactory Cleft During Covid-19, Matthew Miller, Kristy Carlson, Jayme Dowdall, Christie Barnes, Sam Pate

Graduate Medical Education Research Journal

The severe acute respiratory syndrome SARS-CoV-2 pandemic has posed significant challenges to hospital and public health systems in the United States. In response to a shortage in nasopharyngeal swabs, our institution developed, tested, and deployed 3D-printed swabs to obtain a specimen for testing. A patient was tested in preparation for a scheduled Esophagogastrodeuodenoscopy. During the procedure the swab broke and a portion remained in the superior meatus and olfactory cleft. This case study describes the process of locating and removing the broken sections of the 3D-printed swab. In response to this incident, 3D-printing teams test swabs for sample collection and …


Covid-19 Outbreak Impact On Plastic Surgery Residents From Romania, Cristina N. Marina, Daniela E. Gheoca-Mutu, Laura Răducu, Adelaida Avino, Lăcrămioara A. Brîndușe, Corina M. Stefan, Razvan V. Scaunasu, Cristian R. Jecan Sep 2020

Covid-19 Outbreak Impact On Plastic Surgery Residents From Romania, Cristina N. Marina, Daniela E. Gheoca-Mutu, Laura Răducu, Adelaida Avino, Lăcrămioara A. Brîndușe, Corina M. Stefan, Razvan V. Scaunasu, Cristian R. Jecan

Journal of Mind and Medical Sciences

The COVID-19 outbreak triggered a global crisis with long-term effects on people’s daily lives. It has altered surgical practice and education and imposed major changes in healthcare systems and resources. In order to analyze the impact the COVID-19 pandemic has had on Romanian Plastic Surgery residents, we carried out an anonymous questionnaire through Google forms. Survey items addressed aspects such as how the pandemic has affected their surgical practice, their exposure to the virus, and the protective measures that have been implemented to minimize risk. Among other results, our study found that nearly 1 in 5 respondents had contact with …


Providing Foundations For An Educational Revolution: Moving Towards An Integrated Perspective, J.D. Wallace, Brian G. Burton, Robert C. Chandler, Douglas G. Darby Sep 2020

Providing Foundations For An Educational Revolution: Moving Towards An Integrated Perspective, J.D. Wallace, Brian G. Burton, Robert C. Chandler, Douglas G. Darby

School of Information Technology and Computing

The pandemic of Spring 2020 necessitated a rapid switch in teaching methods around the world. Most significantly was the revolutionary transition from face to face instruction to remote, distance, or virtual teaching/learning and the resultant online “new normal” that continues to ripple across the academy and society at large. This new reality has necessitated a paradigmatic shift in how scholars, teachers and administrators understand, create, employ, and assess teaching/learning. It has likewise resulted in a shift in how students, parents, families, and employers understand, value, desire, and prefer educational formats and settings. The authors point to the importance of considering …


Ua12/2/1 College Heights Herald, Vol. 96, No. 6, Wku Student Affairs Sep 2020

Ua12/2/1 College Heights Herald, Vol. 96, No. 6, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

  • Reynolds, Easton. 8 Juveniles Responsible for Recurring Water Throwing Harassment
  • Thornton, Maggie. Marching at a Distance – Marching Band
  • Reynolds, Easton. Local Small Businesses Work to Recover from Pandemic Losses
  • Hendricks, Allie & Preston Romanov. Art for All – SoKY Marketplace
  • Cox, Alex. Editorial Cartoon re: Breonna Taylor
  • Bunton, Gabrielle. I Choose Black Women Every Time
  • Nash, Slim. Commissioner Candidate Slim Nash: Your Right to Vote is Special
  • Hargrove, Matthew. Hilltoppers Look to Bounce Back Against Middle Tennessee State University – Football
  • Kieser, Nick. Budget …


Impacts Of The Covid-19 Pandemic On Global Education, Santanu De Sep 2020

Impacts Of The Covid-19 Pandemic On Global Education, Santanu De

Biology Faculty Books and Book Chapters

Coronavirus Infectious Disease 2019 (COVID-19) has been one of the most dreaded, recent pandemics impacting multifarious global sectors, including education. To control contagion, affected nations ordered academic campus closures and home-schooling plans. Schools, colleges, and universities underwent a paradigm shift adopting internet-based delivery of lectures, synchronously or asynchronously (recorded), with virtual labs. Medical education suffered significantly; suspending student internships in hospitals decreased practical exposure to clinical specialties, impairing students’ performance, and competency.Teachers of traditional classes, with technical assistance, undertook rigorous trainings to restructure pedagogical and assessment strategies online using web/mobile applications and other digital tools.


Colloquium : The Opportunities Of Distance Teaching Sep 2020

Colloquium : The Opportunities Of Distance Teaching

Journal of Civil Law Studies

No abstract provided.


Five Things You Should Know This Week, Georgia Southern University Sep 2020

Five Things You Should Know This Week, Georgia Southern University

A Few Things You Should Know This Week (2020-2023)

  • Now is not the time to become complacent with public health efforts
  • A flu vaccine is especially important this year
  • Complete the census online
  • Voter registration deadline is approaching
  • Stress can be managed.


Science, Leadership, And Public Trust In The Covid-19 Pandemic, Lawrence O. Gostin Sep 2020

Science, Leadership, And Public Trust In The Covid-19 Pandemic, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

Adherence to science in health messaging and public policies helped determine which countries have performed well in containing COVID-19. In the United States, President Trump has interfered with and undermined the work of scientific agencies such as the Centers for Disease Control and Prevention and the Food and Drug Administration, generating public distrust in science and amplifying fears about a future vaccine’s safety and effectiveness. He has also announced that the United States will not join a global partnership that aims to support the development of a vaccine and share access to it.

Science does not always tell us what …


Covid-19 And Social Isolation Endangering Psychological Health Of Older Adults: Implications For Telepsychiatry, Kavita Batra, Amanda Elizabeth Morgan, Manoj Sharma Sep 2020

Covid-19 And Social Isolation Endangering Psychological Health Of Older Adults: Implications For Telepsychiatry, Kavita Batra, Amanda Elizabeth Morgan, Manoj Sharma

Environmental & Global Health Faculty Research

Coronavirus disease-19 (COVID-19) has created a public health emergency and had claimed 911,877 lives at the time of writing this manuscript (September 12, 2020). While everybody is at the risk of acquiring infection following the exposure to SARS-CoV-2, older adults are significantly more likely to experience severe illness, life-threatening complications, hospitalizations, and deaths. As the pandemic evolved, social distancing or shielding efforts as primary prevention were instituted to protect the physical health status of the vulnerable population, with no or limited consideration to the psychological health of the older population. Social isolation and loneliness are the long-standing public health concerns …


Examining Organizational Response And Employee Coping Behaviors Amid The Covid-19 Pandemic, Mendiola Teng-Calleja, Jaimee Felice Caringal-Go, Jason O. Manaois, Ma. Queenie Y. Isidro, Rae Mark S. Zantua Sep 2020

Examining Organizational Response And Employee Coping Behaviors Amid The Covid-19 Pandemic, Mendiola Teng-Calleja, Jaimee Felice Caringal-Go, Jason O. Manaois, Ma. Queenie Y. Isidro, Rae Mark S. Zantua

Psychology Department Faculty Publications

Using the crisis in context theory (CCT) as an ecological framework to understanding human behaviors, the study examined organizational responses and individual employee coping behaviors to mitigate the impact of the COVID-19 pandemic. Drawing from the perspectives of psychology, organization development, and management, the research examined dependent and independent organization and self-initiated actions that employees deemed helpful in coping with the effects of the crisis. Qualitative data were gathered through online survey from 216 employees in the Philippines, a developing country whose major cities were on community quarantine to minimize the spread of the pandemic. The study identified organizational actions …


Fiscal Impacts: A Literature Review, Jim Robey, Kathleen Bolter Sep 2020

Fiscal Impacts: A Literature Review, Jim Robey, Kathleen Bolter

Reports

No abstract provided.


Non-Respiratory Presentations Of Covid-19, A Clinical Review., Marya Alsamman, Amy Caggiula, Sangrag Ganguli, Monika Misak, Ali Pourmand Sep 2020

Non-Respiratory Presentations Of Covid-19, A Clinical Review., Marya Alsamman, Amy Caggiula, Sangrag Ganguli, Monika Misak, Ali Pourmand

COVID-19 Publications by GW Authors

INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19) is a highly infectious viral syndrome currently threatening millions of people worldwide. It is widely recognized as a disease of the pulmonary system, presenting with fever, cough, and shortness of breath. However, a number of extrapulmonary manifestations have been described in the literature.

OBJECTIVE: In this review, we seek to provide a comprehensive summary of the hematologic, gastroenterological, renal, dermatologic, neurologic, and psychiatric manifestations of COVID-19.

DISCUSSION: Hematological presentations of COVID-19 include laboratory abnormalities such as decreased total lymphocyte count, prolonged prothrombin time (PT), elevated d-dimer, and increased lactate dehydrogenase …


St. Norbert Fights Racial Injustice Sep 2020

St. Norbert Fights Racial Injustice

St. Norbert Times

News

  • St. Norbert Fights Racial Injustice
  • #RedAlertRestart: Red Across Campus
  • Lillian Medville Dissects Privilege
  • SNC Exhibits 2020 Senior Art
  • Lecture Series: Art in a Democratic Society
  • Leymah Gbowee Advocates for Peace

Opinion

  • COVID-19 Damages Social Life
  • An Update On Our Political Climate
  • Sacrifice and Perseverance
  • The Price of Life

Features

  • University “Uglies”
  • Campus Queens
  • Respect at St. Norbert Looks Like…
  • New Staff: Laura Krull (Sociology)

Entertainment

  • Student Spotlight
  • “The Misfit of Demon King Academy”
  • Book Review: “CHIP” by Lisa Sail
  • Review of “Community”
  • Three Essentials to Watch From Netflix’s BLM Playlist
  • Junk Drawer: Favorite Song of All-Time

Sports

  • COVID-19: A …


Ua12/2/1 College Heights Herald, Vol. 96, No. 5, Wku Student Affairs Sep 2020

Ua12/2/1 College Heights Herald, Vol. 96, No. 5, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

  • Murray, Debra. Voting in College
  • Reynolds, Easton. WKU and Barnes & Noble Partner in 10-year Deal
  • Latimer, Jacob. Online & Hybrid Courses Pose Challenge to Professors
  • Dobbs, Jack & Anna Leachman. Last Ride: Beech Bend Park
  • Lowe, Julianna. A Call to Mitch McConnell – Ruth Bader Ginsburg
  • Stack, Madalyn. Editorial Cartoon re: Ruth Bader Ginsburg
  • Bailey, Carlos. Bowling Green City Commissioner Candidate Shares Statement on the Importance of Voting in Local Elections
  • Kieser, Nick. Football Fans Use New Ticketing App at Home Opener
  • Hargrove, Matthew. …


A Review Of Quarantine Period In Relation To Incubation Period Of Sars-Cov-2, Satya Rashmit Durugu, Hammad Tanzeem, Divya Menghani, Zahid Imran, Priya Krishnan Sep 2020

A Review Of Quarantine Period In Relation To Incubation Period Of Sars-Cov-2, Satya Rashmit Durugu, Hammad Tanzeem, Divya Menghani, Zahid Imran, Priya Krishnan

The University of Louisville Journal of Respiratory Infections

Introduction: The period from exposure to a potential pathogen to the manifestation of symptoms, i.e.  the incubation period, is time the virus spends replicating in the host. An estimation of this period and subsequent quarantine of the host can limit potential spread, particularly in asymptomatic carriers. Effective contact tracing, length of self-quarantine, repeat testing, and understanding of disease transmission are all contingent on a true estimation of this incubation period.

Methods: Articles in English published since December 1st, 2019, on Google scholar, PubMed, and Research Gate, along with bulletins from the World Health Organization and the Centers for Disease Control …


Perinatal Anxiety And Depression During The Covid 19 Pandemic, Helen Xumin Chen, Nancy Selix, Marcianna Nosek Sep 2020

Perinatal Anxiety And Depression During The Covid 19 Pandemic, Helen Xumin Chen, Nancy Selix, Marcianna Nosek

DNP Qualifying Manuscripts

Abstract

The novel coronavirus disease 2019 (COVID-19) outbreak places perinatal women at higher risk of developing anxiety and depression. Uncertainty, fear, and confusion in medical, social, economic, occupational and political aspects of life in the US add to existing stressors that perinatal women experience. To optimize the quality of perinatal care during the pandemic, appropriate mental health interventions must be implemented to prevent and alleviate perinatal anxiety and depression and improve maternal and infant outcomes. Measures include increased screening, non-pharmacologic and/or pharmacologic interventions and the use of telehealth for care delivery.

Keywords: perinatal anxiety, perinatal depression, COVID-19, SARS CoV-2, maternal …


Strategic Thinking On Strengthening Construction Of National Emergency Prevention And Control System Of Tcm For Major Infectious Diseases, Tong Xiaolin, Zhu Xiangdong, Zhao Linhua, Li Qingwei, Lei Ye, Song Bin, Shao Jianzhu, Wang Qiang, Li Xiuyang, Zheng Yujiao, Fan Aihan Sep 2020

Strategic Thinking On Strengthening Construction Of National Emergency Prevention And Control System Of Tcm For Major Infectious Diseases, Tong Xiaolin, Zhu Xiangdong, Zhao Linhua, Li Qingwei, Lei Ye, Song Bin, Shao Jianzhu, Wang Qiang, Li Xiuyang, Zheng Yujiao, Fan Aihan

Bulletin of Chinese Academy of Sciences (Chinese Version)

COVID-19 epidemic is still raging globally, while China has not only controlled the spread of the epidemic in time, but domestic production and life have gradually recovered. China's epidemic prevention and control work achieved strategic results, and the full participation of Traditional Chinese Medicine (TCM) has become the highlight of the works. However, confronting of sudden major infectious diseases, the emergency reserves and emergency capabilities of TCM are insufficient, especially in the rapid emergency response mechanism, emergency treatment system, professional personnel training, emergency scientific research system and platform construction, and emergency strategic resource reserve. Strengthening the construction of the TCM …


Summary And Recommendations Of Development Of Public Health And Disease Prevention And Control, Sun Dianjianyi, Li Liming Sep 2020

Summary And Recommendations Of Development Of Public Health And Disease Prevention And Control, Sun Dianjianyi, Li Liming

Bulletin of Chinese Academy of Sciences (Chinese Version)

The COVID-19 epidemic in 2020 is an emergency public health event rapidly spreading and hard to prevent and control, causing catastrophic loss of life and almost paralyzing the society. In the absence of specific antiviral drugs and vaccines, China has effectively curbed the spread of COVID-19 by taking non-medical intervention actions decisively and precisely, with the multidepartmental collaborations and involvement of all communities and individuals. However, in the process of combating the epidemic, problems and shortcomings have also been clearly shown in the disease control system and the emergency response system. This review tried to address the weaknesses and issues …


Unusual Case Of Pump Thrombosis In Lvad Patient With Covid-19 — Diagnostic Challenges, William H. Frick Md, Ryan D. Mallory, Maya Guglin, Eve Anderson, Erin N. Lushin, Rey P. Vivo, Kashif Saleem, Roopa A. Rao Sep 2020

Unusual Case Of Pump Thrombosis In Lvad Patient With Covid-19 — Diagnostic Challenges, William H. Frick Md, Ryan D. Mallory, Maya Guglin, Eve Anderson, Erin N. Lushin, Rey P. Vivo, Kashif Saleem, Roopa A. Rao

The VAD Journal

We present the first reported case of left ventricular assist device (LVAD) pump thrombosis in the setting of the coronavirus pandemic. We describe the clinical features of the case which helped to differentiate coronavirus disease 19 (COVID-19) from LVAD pump thrombosis. The patient is 56-year-old female supported by destination LVAD therapy. She was originally implanted with a HeartMate II device in 2015 and underwent two pump exchanges in 2017 and 2019 for pump thrombosis, despite medication adherence. Shortly after routine lab work revealed near doubling of her lactate dehydrogenase (LDH) levels, she tested positive for COVID-19. She then developed power …


Case Report: Tocilizumab For The Treatment Of Sars-Cov-2 Infection In A Patient With Aplastic Anemia, Gina Keiffer, Zach French, Lindsay Wilde, Joanne Filicko-O'Hara, Usama Gergis, Adam Binder Sep 2020

Case Report: Tocilizumab For The Treatment Of Sars-Cov-2 Infection In A Patient With Aplastic Anemia, Gina Keiffer, Zach French, Lindsay Wilde, Joanne Filicko-O'Hara, Usama Gergis, Adam Binder

Department of Medicine Faculty Papers

While cytokine storm develops in a minority of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, novel treatment approaches are desperately needed for those in whom it does. Tocilizumab, an interleukin-6 receptor antibody, has been utilized for the treatment of cytokine storm in a number of severe inflammatory conditions, including in patients with severe coronavirus disease 2019 (COVID-19). Here, we present the first published case utilizing this therapy in a patient with underlying immunodeficiency. Our patient with aplastic anemia developed cytokine storm due to COVID-19 manifested by fever, severe hypoxia, pulmonary infiltrates, and elevated inflammatory markers. Following treatment …


A Review Of The Preclinical And Clinical Efficacy Of Remdesivir, Hydroxychloroquine, And Lopinavir-Ritonavir Treatments Against Covid-19, Dawid Maciorowski, Samir Z. El Idrissi, Yash Gupta, Brian J. Medernach, Michael B. Burns, Daniel P. Becker Ph.D., Ravi Durvasula, Prakasha Kempaiah Sep 2020

A Review Of The Preclinical And Clinical Efficacy Of Remdesivir, Hydroxychloroquine, And Lopinavir-Ritonavir Treatments Against Covid-19, Dawid Maciorowski, Samir Z. El Idrissi, Yash Gupta, Brian J. Medernach, Michael B. Burns, Daniel P. Becker Ph.D., Ravi Durvasula, Prakasha Kempaiah

Chemistry: Faculty Publications and Other Works

In December of 2019, an outbreak of a novel coronavirus flared in Wuhan, the capital city of the Hubei Province, China. The pathogen has been identified as a novel enveloped RNA beta-coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus SARS-CoV-2 is associated with a disease characterized by severe atypical pneumonia known as coronavirus 2019 (COVID-19). Typical symptoms of this disease include cough, fever, malaise, shortness of breath, gastrointestinal symptoms, anosmia, and, in severe cases, pneumonia.1 The high-risk group of COVID-19 patients includes people over the age of 60 years as well as people with existing cardiovascular …