Digital Commons Network^™

Association Of National Covid-19 Cases With Objectively And Subjectively Measured Mental Health Proxies In The Austrian Football League–An Epidemiological Study, Antje Van Der Zee-Neuen, Alexander Seymer, Dagmar Schaffler-Schaden, Jürgen Herfert, James Óbrien, Tim Johansson, Patrick Kutschar, Stephan Ludwig, Thomas Stöggl, David Keeley, Maria Flamm, Jürgen Osterbrink

Research outputs 2014 to 2021

We aimed to explore the association of national COVID-19 data with the objective and subjective mental health proxies (i.e. location variance, self-reported sleep quality, level of recovery, perceived risk of infection) in team and staff members of five professional Austrian Football clubs. Data were conveniently collected during the implementation of a novel monitoring concept. The concept was designed to enable safe continuation of professional Football during the COVID-19 pandemic. These data were matched with Austrian COVID-19 data and smartphone collected location data. Multivariable linear regression models explored the association of COVID-19, defined as daily novel or active Austrian cases of …

Impact Of Covid-19 On Cryptocurrencies: Evidence On Information Transmission Through Economic And Financial Market Sentiments, Irfan Haider Shakri, Jaime Yong, Erwei Xiang

Research outputs 2014 to 2021

This paper investigates the relationship between the COVID-19 crisis and the two leading cryptocurrencies, Bitcoin and Ethereum, from 31 December 2019 to 18 August 2020. We also use an economic news sentiment index and financial market sentiment index to explore the possible mechanisms through which COVID-19 impacts cryptocurrency. We employ a VAR Granger Causality framework and Wavelet Coherence Analysis and find the cryptocurrency market was impacted in the early phase of the sample period through economic news and financial market sentiments, but this effect diminished after June 2020.

Nonprofit Capacity To Manage Hurricane-Pandemic Threat: Local And National Perspectives On Resilience During Covid-19, Nicole S. Hutton, Steven W. Mumford, Marina Saitgalina, Juita-Elena (Wie) Yusuf, Joshua G. Behr, Rafael Diaz, John J. Kiefer

Political Science & Geography Faculty Publications

This paper examines nonprofits' capacity for responding to simultaneous hurricane-pandemic threat, addressing: (1) strategies nonprofits use to deliver services during the COVID-19 pandemic, and (2) how natural hazards may affect nonprofit roles in emergency service delivery during a pandemic. Data come from a survey of New Orleans-based nonprofits demonstrating effects of pandemic on local nonprofit service delivery, and workshops with U.S. coastal community stakeholders exploring expectations for nonprofit roles in emergency operations nationwide. Nonprofits have applied resilient strategies including virtual operations, staff reductions, and funding diversification, but vulnerabilities remain. Findings guide a research agenda for building nonprofit and community resilience.

Authentic Leadership In Crisis Scenarios: A Phenomenological Examination Of The Lived Experience Of Corporate Leaders During The Covid-19 Pandemic, Natasha Brown

Theses and Dissertations

The coronavirus pandemic unleashed a host of challenges worldwide including political instability, financial turmoil, and public health concerns in 2020. As a result, new constraints including remote work environments, shifting consumer demands, and supply chain disruptions created a complex landscape for businesses. Leaders within companies have been confronted with crisis scenarios. The purpose of the study was to understand the role of authentic leadership in helping corporate leaders navigate the COVID-19 pandemic crisis. The central research question was: To what extent, if any, does authentic leadership enable leaders to navigate crises effectively? The research is focused on the intersection of …

Sentiment Analysis Of Long-Term Social Data During The Covid-19 Pandemic, Sophanna Ek, Marco Curci, Xiaokun Yang, Beiyu Lin, Pinchao Liu, Hailu Xu

Computer Science Faculty Publications

The COVID-19 pandemic has bringing the “infodemic” in the social media worlds. Various social platforms play a significant role in instantly acquiring the latest updates of the pandemic. Social media such as Twitter and Facebook produce vast amounts of posts related to the virus, vaccines, economics, and politics. In order to figure out how public opinion and sentiments are expressed during the pandemic, this work analyzes the long-term social posts from social media and conducts sentiment analysis on tweets within 12 months. Our findings show the trend topics of long-term social communities during the pandemic and express people’s attitudes towards …

Helping Healthcare Teams Save Lives During Covid-19: Insights And Countermeasures From Team Science

Faculty, Staff and Student Publications

As the COVID-19 pandemic has ravaged the United States, health care teams are on the frontlines of this global crisis, often navigating harrowing conditions at work, such as a lack of personal protective equipment and staffing shortages, and distractions at home, including worries about elderly relatives or making childcare arrangements. While the nature and severity of stressors impacting health care teams are in many ways unprecedented, decades of psychological research exploring teamwork in extreme contexts can provide insights to understand and improve outcomes for teams in a crisis. This review highlights the psychological principles that apply to teams in a …

Prevalence And Factors Associated With Mental Health Symptoms In Adults Undergoing Covid-19 Testing, Yen-Chi L Le, Christine D Gordon, Kevin O Hwang

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVE: Understanding the mental health impact of the COVID-19 pandemic on persons receiving COVID-19 testing will help guide mental health interventions. We aimed to determine the association between sociodemographic factors and mental health symptoms at 8 weeks (baseline) after a COVID-19 test, and compare prevalence of mental health symptoms at baseline to those at 16-week follow-up.

MATERIALS AND METHODS: Prospective cohort study of adults who received outpatient COVID-19 testing at primary care clinics. Logistic regression analyses were used to assess the association between sociodemographic characteristics and COVID-19 test results with mental health symptoms. Mental health symptoms reported at …

Prevalence And Factors Associated With Mental Health Symptoms In Adults Undergoing Covid-19 Testing, Yen-Chi L Le, Christine D Gordon, Kevin O Hwang

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVE: Understanding the mental health impact of the COVID-19 pandemic on persons receiving COVID-19 testing will help guide mental health interventions. We aimed to determine the association between sociodemographic factors and mental health symptoms at 8 weeks (baseline) after a COVID-19 test, and compare prevalence of mental health symptoms at baseline to those at 16-week follow-up.

MATERIALS AND METHODS: Prospective cohort study of adults who received outpatient COVID-19 testing at primary care clinics. Logistic regression analyses were used to assess the association between sociodemographic characteristics and COVID-19 test results with mental health symptoms. Mental health symptoms reported at …

Prevalence And Factors Associated With Mental Health Symptoms In Adults Undergoing Covid-19 Testing, Yen-Chi L Le, Christine D Gordon, Kevin O Hwang

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVE: Understanding the mental health impact of the COVID-19 pandemic on persons receiving COVID-19 testing will help guide mental health interventions. We aimed to determine the association between sociodemographic factors and mental health symptoms at 8 weeks (baseline) after a COVID-19 test, and compare prevalence of mental health symptoms at baseline to those at 16-week follow-up.

MATERIALS AND METHODS: Prospective cohort study of adults who received outpatient COVID-19 testing at primary care clinics. Logistic regression analyses were used to assess the association between sociodemographic characteristics and COVID-19 test results with mental health symptoms. Mental health symptoms reported at …

The Healthcare System And Pandemics: Where Is The Market Failure?, Sophia S. Helland, Edward R. Morrison

Faculty Scholarship

Barak D. Richman and Steven L. Schwarcz argue that healthcare providers played a central – and failing – role in stemming the fallout from the COVID-19 pandemic. Analogizing to the financial crisis of 2008, they view our healthcare system as a collection of providers, each maximizing returns to its own stakeholders in a laissez-faire regulatory environment that ignored the essential interconnectedness of providers. Because neither hospitals nor regulators were attuned to this interconnectedness, our healthcare system was unprepared for the pandemic, resulting in a reduced standard of care. Just as Dodd-Frank and related legislation view financial institutions as part of …

Benefit-Cost Analysis Of Covid-19 Policy Intervention At The State And National Level, James L. Doti

Economics Faculty Articles and Research

This study analyzes the benefits of statewide policy intervention in reducing COVID-19 deaths and the costs of that intervention in lost jobs and lower real gross state product (RGSP). Policy interventions are measured by the Oxford stringency index which places a daily numerical value on the level of a state’s policy intervention.

Empirical evidence is provided that shows policy interventions have reduced COVID-19 deaths by 375,000 lives in 2020. On the cost side, it was found that policy intervention resulted in a loss of 7.3 million jobs and a decline of $410 billion in RGSP.

The study concludes by integrating …

N95 Respirator Reuse, Decontamination Methods, And Microbial Burden: A Randomized Controlled Trial, Michael C Lorenz, Jumah Ahmad, Ronda Alexander, William Bryan, Luke Burke, Martin J Citardi, Jose Elias, Tang Ho, Jack Jacob, Garren Low, Pedro Miramón, Aniruddha U Patki, William C Yao, Amber U Luong

Faculty, Staff and Student Publications

PURPOSE: To evaluate the effectiveness and ease of N95 respirator decontamination methods in a clinic setting and to identify the extent of microbial colonization on respirators associated with reuse.

METHODS: In a prospective fashion, N95 respirators (n = 15) were randomized to a decontamination process (time, dry heat, or ultraviolet C light [UVC]) in outpatient clinics. Each respirator was re-used up to 5 separate clinic sessions. Swabs on each respirator for SARS-CoV-2, bacteria, and fungi were obtained before clinic, after clinic and post-treatment. Mask integrity was checked after each treatment (n = 68). Statistical analyses were performed to determine factors …

N95 Respirator Reuse, Decontamination Methods, And Microbial Burden: A Randomized Controlled Trial, Michael C Lorenz, Jumah Ahmad, Ronda Alexander, William Bryan, Luke Burke, Martin J Citardi, Jose Elias, Tang Ho, Jack Jacob, Garren Low, Pedro Miramón, Aniruddha U Patki, William C Yao, Amber U Luong

Faculty, Staff and Student Publications

PURPOSE: To evaluate the effectiveness and ease of N95 respirator decontamination methods in a clinic setting and to identify the extent of microbial colonization on respirators associated with reuse.

METHODS: In a prospective fashion, N95 respirators (n = 15) were randomized to a decontamination process (time, dry heat, or ultraviolet C light [UVC]) in outpatient clinics. Each respirator was re-used up to 5 separate clinic sessions. Swabs on each respirator for SARS-CoV-2, bacteria, and fungi were obtained before clinic, after clinic and post-treatment. Mask integrity was checked after each treatment (n = 68). Statistical analyses were performed to determine factors …

Convergent Evidence For The Antiviral Effects Of Several Fda-Approved Phenothiazine Antipsychotics Against Sars-Cov-2 And Other Coronaviruses

Faculty, Staff and Student Publications

No abstract provided.

Awareness And Preparedness Of Healthcare Workers Against The First Wave Of The Covid-19 Pandemic: A Cross-Sectional Survey Across 57 Countries, Vuong Ngoc Thao Uyen, Le Van Truong, Mai Ngoc Luu, Shyam Prakash Dumre, Atsuko Imoto, Peter N Lee, Dao Ngoc Hien Tam, Sze Jia Ng, Mohammad Rashidul Hashan, Mitsuaki Matsui, Nguyen Tran Minh Duc, Sedighe Karimzadeh, Nut Koonrungsesomboon, Chris Smith, Sharon Cox, Kazuhiko Moji, Kenji Hirayama, Le Khac Linh, Kirellos Said Abbas, Tran Nu Thuy Dung, Tareq Mohammed Ali Al-Ahdal, Emmanuel Oluwadare Balogun, Nguyen The Duy, Mennatullah Mohamed Eltaras, Trang Huynh, Nguyen Thi Linh Hue, Bui Diem Khue, Abdelrahman Gad, Gehad Mohamed Tawfik, Kazumi Kubota, Hoang-Minh Nguyen, Dmytro Pavlenko, Vu Thi Thu Trang, Le Thuong Vu, Tran Hai Yen, Nguyen Thi Yen-Xuan, Luong Thi Trang, Vinh Dong, Akash Sharma, Vu Quoc Dat, Mohammed Soliman, Jeza Abdul Aziz, Jaffer Shah, Pham Dinh Long Hung, Yap Siang Jee, Dang Thuy Ha Phuong, Tran Thuy Huong Quynh, Hoang Thi Nam Giang, Vy Thi Nhat Huynh, Nguyen Anh Thi, Nacir Dhouibi, Truc Phan, Vincent Duru, Nguyen Hai Nam, Sherief Ghozy, Tmgh-Global Covid-19 Collaborative

Faculty, Staff and Student Publications

BACKGROUND: Since the COVID-19 pandemic began, there have been concerns related to the preparedness of healthcare workers (HCWs). This study aimed to describe the level of awareness and preparedness of hospital HCWs at the time of the first wave.

METHODS: This multinational, multicenter, cross-sectional survey was conducted among hospital HCWs from February to May 2020. We used a hierarchical logistic regression multivariate analysis to adjust the influence of variables based on awareness and preparedness. We then used association rule mining to identify relationships between HCW confidence in handling suspected COVID-19 patients and prior COVID-19 case-management training.

RESULTS: We surveyed 24,653 …

Still Learning: Covid Through The Eyes Of A Medical Student, Alexis Strahan

HCA Healthcare Journal of Medicine

As a first-year medical student when the COVID-19 pandemic found a foothold, I felt an overwhelming amount of emotions that accompanied the pandemic’s spread. Fear, although a reasonable choice, was not the first emotion that I experienced. In fact, it was a general feeling of paralysis. I had not six months prior taken an oath to commit my career and life to the service of the public’s health care needs, yet I could provide little more than the textbook knowledge of biochemistry or genetics from my first semester of learning. My hands felt unarmed and unskilled for the fight. What …

Covid-19: Race For Vaccine, L. Hayley Burgess, Jason J. Braithwaite, Emily Singleton, Aaron M. Young, Mandelin K. Cooper

HCA Healthcare Journal of Medicine

The world is in the midst of a pandemic from COVID-19, a disease caused by the virus SARS-CoV-2. Despite broad mitigation efforts, new cases continue with 74 million cases and 1.6 million deaths worldwide. Regardless of previous research efforts, there is no commercially available vaccine for any coronavirus. Novel vaccine development has historically taken at least 10 years from discovery to availability with only a 6% market entry probability.

With the global impact, there is an urgency to expedite a vaccine to protect the population. The U.S. government launched Operation Warp Speed with the goal to produce and deliver 300 …

Importance Of Awareness Of Adverse Drug Reaction Reporting During The Covid-19 Pandemic, Heather Ellis, Hale Z. Toklu

HCA Healthcare Journal of Medicine

Health care professionals hold the responsibility of reporting any adverse drug reactions in order to learn about new therapy and how best to safely care for our patients. The information derived from case publications and FDA MedWatch reports are essential to accumulate information and increase awareness for the possible risks of new drugs.

Hubungan Motivasi Belajar Dengan Komunikasi Pembelajaran Sistem E-Learning Pada Mahasiswa Pgsd Di Masa Pandemi Covid-19, Anang Fathoni, Ali Mustadi, Wahyu Kurniawati

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This research aimed to determine the motivation of learning, communication of e-learning system, and relationship motivation learning and communication learning system of students of primary teacher Education, University PGRI Yogyakarta at the Covid-19 pandemic. This research used quantitative approaches with associative methods. The location of this research at PGRI University Yogyakarta with respondents amounted to 159 students of 2nd semester, consisting of 25 male students and 134 female students. The collection of research data used a questionnaire with a Likert rating scale. Analysis of data by using the correlation formula of product-moment from Pearson with the help of SPSS version …

Combating Covid-19 Infodemic In Nigerian Rural Communities: The Imperatives Of Traditional Communication Systems, Joseph M. Lucas, Tordue Simon Targema, Abubakar Jibril, Elkanah Obadiah Sambo, Bako Ali Istifanus

ASEAN Journal of Community Engagement

Since the outbreak of COVID-19 in December 2019, substantial attention has been devoted to combating the infodemic that has come to characterize it with the potential to prevent its effective containment. This is undoubtedly a very difficult task, especially in Nigerian rural communities that are characterized by severe lack of the requisite facilities to access information on modern media platforms, compounded by high illiteracy and poverty rates. This study presents a case for the utilization of people-oriented, traditional communication systems in combatting the infodemic at the grassroots level. It contends that, given the peculiarities of the country’s rural settlements, traditional …

Community Engagement In Covid-19 Responses: Evidence From Qualitative Interface With Community Opinion Leaders In Enugu, Nigeria, Prince Agwu, Chinweoke Methodius Ugwu, Chidera Florence Eke

ASEAN Journal of Community Engagement

Successful stories of community engagement existed during the Ebola disease outbreak in Liberia, indicating that a combination of government and community efforts are needed in addressing pandemics or epidemics. However, for communities to rise to the challenge of containing and combatting the spread of any disease, they must be communicated most effectively and supported by the government. Therefore, our study investigates how applicable successful community engagement has been in the charge against the Coronavirus disease 2019 (COVID-19) in Nigeria. Through telephone interviews, we sourced data from 12 community opinion leaders in Enugu State, Nigeria. After conducting a thematic analysis of …

The Legacy Of Racism And Covid-19, Adedayo Okanlawon

MEDI 9331 Scholarly Activities Clinical Years

This perspective piece discusses the interplay between Covid-19, the legacy of racism in America, and their synergistic effects on the black community. Personal racially charged experiences in conjunction with notable stories of injustice in medicine are used to set the stage. The pandemic's disparate impact on black communities are then discussed with suggestion on how to mitigate these issues.

Socio-Demographic Determinants Of Indonesian Mothers’ Psychological Distress During Covid-19 Pandemic, Laila Qadariah, Fitri Ariyanti Abidin, Fitri Yustikasari Lubis, Vidya Anindhita

Makara Human Behavior Studies in Asia

The Indonesian government imposed a large-scale social restriction policy to prevent the spread of COVID-19. This policy affected the community, including mothers, and may have caused psychological strain on them. This study aimed to (i) establish a dataset on the psychological distress reported by mothers in Indonesia and (ii) identify demographic factors and pandemic-related characteristics that determine psychological distress. An online survey was administered from April 20 to April 25, 2020, and 1534 surveys were submitted. Bivariate and multivariate regression models were constructed to examine the associations between sociodemographic variables, depression, anxiety, and stress. The results demonstrated that the level …

“Why Can Other People Live Normally While I Cannot?”: An Application Of Telecounseling Due To Covid-19, Kusumasari Kartika Hima Darmayanti, Efan Yudha Winata, Erlina Anggraini

Makara Human Behavior Studies in Asia

In Nusa Tenggara Barat province, on May 04, 2020, there were 275 cases out of 11,587 total cases in Indonesia. COVID19 not only has an impact on physical health issues, but it also impacts on psychological issues. One of the psychological issues is how society experiences negative emotion (e.g., depression) during the spread of COVID-19. This study aimed to explore the telecounseling process on the individual who had experienced negative emotion especially in the case of depressive disorder in the COVID-19 Nusa Tenggara Barat province. This study used a single-case research design approach, and the collected data were analyzed qualitatively. …

Potential Of Jamu In Nanotechnology Perspective As An Alternative Treatment For Covid-19, Dhadhang Wahyu Kurniawan, Azis Ikhsanudin

Pharmaceutical Sciences and Research

The world seems to be recovering at this time, especially because of the 2019 global coronavirus disease pandemic (COVID-19) caused by the Coronavirus 2 virus (SARS-CoV-2). This virus is similar to other β-coronaviruses through several steps to enter and bind angiotensin-converting enzyme 2 (ACE2) as the main receptor. This binding, particularly in the respiratory epithelium and alveoli of the lungs, affects harmony in human host cells. No specific vaccines and antivirals are available to date as drug investigations are still ongoing. However, many Indonesians consume herbal medicine, especially 'empon-empon' containing the Zingiberaceae family, to protect their health from COVID-19. So …

The 21st Century Global Digital Economies Revolution And The Aftermath Of Covid-19 Pandemic: Some Anticipated Implication Changes For Developing Nations, Agyei Fosu

ASEAN Journal of Community Engagement

The 21^st century digital global economies era changed developmental approaches drastically to a point where most researchers, policy makers, and developers have asserted that to achieve economic development for developing nations; it is paramount for Information and Communications Technologies (ICTs) investments in all sectors contributing to their economy. The current COVID-19 pandemic and the various measures taken by governments such as lockdown, curfew, companies asking employees to work from home, and the use of e-learning by schools to curb the disease brings into perspective the assertion raised by various scholars about the need for developing nations to invest in …

Let Nutrition Be Your Vaccine Amid Covid-19- A Narrative Review, Vidya Rajesh

Manipal Journal of Medical Sciences

There has been a growing body of evidence highlighting the radical effect of nutrition on the immune system and disease susceptibility. The current COVID-19 crisis awakens an urgent calling for optimum nutrition which boosts immunity and prevents diseases, just like a vaccine. Though there have been several national guidelines regarding diet during COVID-19, there has been sparse research and literature available in this field. This review aims to summarise the existing evidence on various aspects of nutrition and immunity pertaining to the COVID-19 crisis. Literature and search strategy included PubMed and Google Scholar for articles on various aspects of nutrition …

“Sampark Snehi”: Telemedicine Consultation In Covid-19 Times At A Private Medical College Hospital – Digitalised Solution, Vijetha Belle

Manipal Journal of Medical Sciences

Every life is precious and every patient matters: In a country with 5.5 government beds for 10,000 population, even a marginal increase in hospitalization increases the pressure on the system exponentially. The spread of COVID-19 has kindled the need for transformation from traditional face-to-face doctorpatient communication to a telehealth platform. During the lockdown, reduced access to both outpatient and hospitalization services is proving to be fatal for countless non-covid patients. Taking lead in addressing the health care needs and demands of the society we cater to, E-consultation which has been initiated by most of the medical colleges providing tertiary care, …

Audits For The Minimization Of Eco-Anxiety In The World Economy, Karina Nazarova, Volodymyr Hordopolov, Mariia Nezhyva, Viktoriia Mysiuk, Tetiana Kopotiienko

Journal of Environmental Science and Sustainable Development

The global pandemic of 2019–2020 is changing not only the lives of citizens, but also approaches to business management. The activities of audit companies have not escaped. Problematic and debatable issues need to be addressed to formulate a comprehensive approach to audits in a transformative economic environment and minimize the global economy's eco-anxiety. The purpose of the article is to determine the role of the audit in minimizing the eco-anxiety of the world economy. The study's materials were indicators of the spread of the COVID-19 pandemic in the world, public writings of scientists, official reports of international organizations, regulations, and …

Multifaceted Highly Targeted Sequential Multidrug Treatment Of Early Ambulatory High-Risk Sars-Cov-2 Infection (Covid-19), Peter A. Mccullough, Paul E. Alexander, Robin Armstrong, Cristian Arvinte, Alan F. Bain, Richard P. Bartlett, Robert L. Berkowitz, Andrew C. Berry, Thomas J. Borody, Joseph H. Brewer, Adam M. Brufsky, Teryn Clarke, Roland Derwand, Alieta Eck, John Eck, Richard A. Eisner, George C. Fareed, Angelina Farella, Silvia Ns Fonseca, Charles E. Geyer, Russell S. Gonnering, Karladine E. Graves, Kenneth Bv Gross, Sabine Hazan, Kristin S. Held, H. Thomas Hight, Stella Immanuel, Michael M. Jacobs, Joseph A. Ladapo, Lionel H. Lee, John Littell, Ivette Lozano, Harpal S. Mangat, Ben Marble, John E. Mckinnon, Lee D. Merritt, Jane M. Orient, Ramin Oskoui, Donald C. Pompan, Brian C. Procter, Chad Prodromos, Juliana Cepelowicz Rajter, Jean-Jacques Rajter, C. Venkata S. Ram, Salete S. Rios, Harvey A. Risch, Michael Ja Robb, Molly Rutherford, Martin Scholz, Marilyn M. Singleton, James A. Tumlin, Brian M. Tyson, Richard G. Urso, Kelly Victory, Elizabeth Lee Vliet, Craig M. Wax, Alexandre G. Wolkoff, Vicki Wooll, Vladimir Zelenko

Infectious Diseases Articles

The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness, hospitalizations, and death. The complex and multifaceted pathophysiology of life-threatening COVID-19 illness including viral mediated organ damage, cytokine storm, and thrombosis warrants early interventions to address all components of the devastating illness. In countries where therapeutic nihilism is prevalent, patients endure escalating symptoms and without early treatment can succumb to delayed in-hospital care and death. Prompt early initiation of sequenced multidrug therapy (SMDT) is a widely and currently available solution to stem the tide of hospitalizations and death. A multipronged therapeutic approach includes 1) adjuvant nutraceuticals, …