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Covid-19 And Its Impact(S) On Innovation, Clark Asay, Stephanie Plamondon Bair Jan 2021

Covid-19 And Its Impact(S) On Innovation, Clark Asay, Stephanie Plamondon Bair

Faculty Scholarship

In previous work, we explored how certain characteristics of adversity are often more conducive to innovation than others. In this Article, prepared as part of the Lee E. Teitelbaum Utah Law Review Symposium—The Law & Ethics of Medical Research, we review some of that work and apply it specifically to the COVID-19 context. We conclude by assessing certain policy implications in light of how the COVID-19 pandemic has both spurred and hindered innovation.


Predicting College Enrollment During A Global Crisis, Jake Colin Hewins Jan 2021

Predicting College Enrollment During A Global Crisis, Jake Colin Hewins

Honors Theses and Capstones

This paper looks at how the COVID-19 pandemic has affected college enrollment at colleges and universities within New England, how this effect compares to the Great Recession of 2008-2009, and then predict future trends in total enrollment by first identifying the major factors of change in college enrollment during the Great Recession and COVID-19 pandemic. These factors include the perceived value of getting a degree by traditional and nontraditional students, where colleges and universities generate their revenue, and where and how students are enrolling in higher education, and the cost and value of online learning. Based on these factors, questions …


Covid-19 And The Effects On World's Most Admired Companies, Justin P. Mooney Jan 2021

Covid-19 And The Effects On World's Most Admired Companies, Justin P. Mooney

Honors Theses and Capstones

No abstract provided.


Covid-19’S Impact On Human Trafficking: The Invisible Industry In New Hampshire, Brittany Dunkle Jan 2021

Covid-19’S Impact On Human Trafficking: The Invisible Industry In New Hampshire, Brittany Dunkle

Honors Theses and Capstones

Human trafficking is a modern-day form of slavery that operates on the premise of exploitation, such as forced prostitution and labor, and organ trafficking. This is a global industry resulting in billions. Despite the current global pandemic, COVID-19, putting a halt to many livelihoods around the world, human trafficking will persist, but in conditions that are potentially more harmful for the victims. Victims of trafficking are in an increasingly vulnerable position, and it is important to establish possible mechanisms to protect as many victims and potential victims as possible. Typical risk factors (i.e., poverty, state’s interest vs. individual interest, unemployment) …


Learning Organization In A Time Of Crisis: A Case Study Of Logistics And Freight, Llc And Covid-19, Matt Meador Jan 2021

Learning Organization In A Time Of Crisis: A Case Study Of Logistics And Freight, Llc And Covid-19, Matt Meador

Electronic Theses and Dissertations Archive

The term learning organization (LO) is a widely used conversation piece in corporate cultures, particularly among managing practitioners and leaders in talent management, learning and development, and leadership development (Marquardt, Berger, & Loan, 2004). Given the market upheaval due to COVID-19, this work incorporates current literature on a learning organization's dimensions, known as characteristics, through a qualitative approach. This investigation aims to capture the experiences of managing practitioners as the logistics community revisits learning strategies due to the extremely rapid change of COVID-19 (Ferguson et al., 2020; Marquardt, Berger, & Loan, 2004). Marsick and Watkins dimensions of a learning organization …


The Roles And Functions Of The Virtual School Counselor, Latraci Aldridge Jan 2021

The Roles And Functions Of The Virtual School Counselor, Latraci Aldridge

Electronic Theses and Dissertations Archive

As technology increases, so does the integration of technology in educational settings. That integration also extends to school counseling and the field of counseling in its entirety. The purpose of this study is to compare the role and functions of an online and traditional setting school counselor. Due to virtual/online school counseling still being in the early stages, there is limited research about what a virtual school counseling program looks like or the academic outcomes for students enrolled in virtual schools. As more virtual schools emerge, it is imperative that we investigate the best practices for online school counseling. Should …


Infrared Based Saliva Screening Test For Covid-19, Bayden R. Wood, Kamila Kochan, Diana E. Bedolla, Natalia Salazar‐Quiroz, Samantha L. Grimley, David Perezguaita, Matthew J. Baker, Jitraporn Vongsvivut, Mark J. Tobin, Keith R. Bambery, Dale Christensen, Shivani Pasricha, Anthony K. Eden, Aaron Mclean Jan 2021

Infrared Based Saliva Screening Test For Covid-19, Bayden R. Wood, Kamila Kochan, Diana E. Bedolla, Natalia Salazar‐Quiroz, Samantha L. Grimley, David Perezguaita, Matthew J. Baker, Jitraporn Vongsvivut, Mark J. Tobin, Keith R. Bambery, Dale Christensen, Shivani Pasricha, Anthony K. Eden, Aaron Mclean

Articles

Abstract: Severe acute respiratory syndrome coronavirus 2 has resulted in an unprecedented need for diagnostic testing that is critical in controlling the spread of COVID-19. We propose a portable infrared spectrometer with purpose-built transflection accessory for rapid point-of-care detection of COVID-19 markers in saliva. Initially, purified virion particles were characterized with Raman spectroscopy, synchrotron infrared (IR) and AFM-IR. A data set comprising 171 transflection infrared spectra from 29 patients testing positive for SARS-CoV-2 by RT-qPCR and 28 testing negative, was modeled using Monte Carlo Double Cross Validation with 50 randomized test and model sets. The testing sensitivity was 93 % …


A Flair To Remember: Innovative Use Of Technology During Covid-19 Focus On Weddings, Carla Rosas, Danielle Lynch, Mj Adekanmbi, Simioluwa Opayemi Jan 2021

A Flair To Remember: Innovative Use Of Technology During Covid-19 Focus On Weddings, Carla Rosas, Danielle Lynch, Mj Adekanmbi, Simioluwa Opayemi

Case Studies

Student blog series from MSc in Event Management students at TU Dublin.

In this blog post Carla Rosas, Danielle Lynch, MJ Adekanmbi and Simioluwa Opayemi interview event planner Gabriella Olukoya from luxury events company A Flair to Remember. Gabriella gives vital insight on the current state of the wedding industry and also on how to ‘flip the script’ and use the ‘negatives’ and make them positives to elevate an events company. As a current ‘Regional Finalist’ for Wedding Planner of the Year, Gabby is a prime example of ‘Creating Success’ during COVID-19 by adding and implementing technology into their events …


Demystifying Remote Research In Anthropology And Area Studies, Kaitlyn Ugoretz Jan 2021

Demystifying Remote Research In Anthropology And Area Studies, Kaitlyn Ugoretz

Asia Pacific Perspectives

Physically cut off from locations and archives central to our work due to restrictions in response to the global COVID-19 pandemic, area studies scholars must reimagine what constitutes rigorous and responsible research in their respective disciplines. The practice of remote research, however, is not a new one. Digital ethnography, an admittedly niche subdiscipline of anthropology, has long been grappling with the issues of how to value and conduct remote research. This essay explores a number of misconceptions regarding digital and remote research that may aid in contextualizing and coming to terms with the anxieties the broader scholarly community faces. I …


Is It Possible To Think Of A “Chinese Pacific” In The Making? Decolonizing Anthropology In The Asia-Pacific Region, Rodolfo Maggio Jan 2021

Is It Possible To Think Of A “Chinese Pacific” In The Making? Decolonizing Anthropology In The Asia-Pacific Region, Rodolfo Maggio

Asia Pacific Perspectives

The travel restrictions implemented to limit the spread of the COVID19 pandemic prevent fieldworkers from collecting ethnographic data in the Pacific. The possibility of collecting first-hand data about indigenous perspectives on the recent growth of the Chinese presence and influence is therefore limited too. Despite the critical need for this kind of data, the situation provides an opportunity for a concerted reflection on the conceptual tools scholars deploy to study China in the Pacific. A decolonial methodology seems necessary to prevent the superimposition of preconceived ideas upon indigenous views that, at the moment, can only be accessed in journalistic and …


Do Online Courses Provide An Equal Educational Value Compared To In-Person Classroom Teaching? Evidence From U.S. Survey Data Using Quantile Regression, Manini Ojha, Mohammad Arshad Rahman Jan 2021

Do Online Courses Provide An Equal Educational Value Compared To In-Person Classroom Teaching? Evidence From U.S. Survey Data Using Quantile Regression, Manini Ojha, Mohammad Arshad Rahman

All Works

Education has traditionally been classroom-oriented with a gradual growth of online courses in recent times. However, the outbreak of the COVID-19 pandemic has dramatically accelerated the shift to online classes. Associated with this learning format is the question: what do people think about the educational value of an online course compared to a course taken in-person in a classroom? We address this question and present a Bayesian quantile analysis of public opinion using a nationally representative survey data from the United States. We find that previous participation in online courses and full-time employment status favor the educational value of online …


Flipping A Virtual Efl Public Speaking Class Integrated With Moocs During The Covid-19 Pandemic, Zhuo Li, Xiaodi Zhou Jan 2021

Flipping A Virtual Efl Public Speaking Class Integrated With Moocs During The Covid-19 Pandemic, Zhuo Li, Xiaodi Zhou

Bilingual and Literacy Studies Faculty Publications

This case study explored Chinese undergraduate EFL students’ attitudes to and perceptions of an online English public speaking course, which employs a virtual flipped classroom model and MOOCs during the COVID-19 pandemic outbreak. Since all classes were moved online, a previously flipped public speaking course integrated with MOOCs was converted into a virtual flipped classroom. All 25 participants of the study were undergraduate students in the science, technology, engineering, and mathematics (STEM) field. Zoom, Blackboard, and QQ instant messenger were platforms utilized in instruction. There were weekly two-hour Zoom meetings with learning activities using MOOCs on Blackboard. The study collected …


Campus Recreation And Fitness Center Utilization During The Covid-19 Pandemic, Keagan Kiely, William Mase, Bridget F. Melton, Haresh Rochani Dr. Jan 2021

Campus Recreation And Fitness Center Utilization During The Covid-19 Pandemic, Keagan Kiely, William Mase, Bridget F. Melton, Haresh Rochani Dr.

Health Sciences & Kinesiology: Faculty Publications

Background

The impact of the COVID-19 pandemic has far reaching effects for college students' health and physical activity behaviors. This analysis focuses on university student fitness center usage pre and during the COVID-19 pandemic. Researchers hypothesized a reduction in fitness center utilization when comparing Fall 2019 to Fall 2020 utilization rates.

Methods

Patterns of the recreation center and fitness center utilization during the COVID-19 pandemic are compared to pre-pandemic patterns of a matched time period in the previous academic year in an observational study. Overall utilization was evaluated using secondary data from the university’s recreation center data system. Six weeks …


The Hr Connection, Georgia Southern University Jan 2021

The Hr Connection, Georgia Southern University

Human Resources (2010-2023)

  • COVID-19 Manager's Guide
  • Policy Updates
  • Ahead Of Phase 1A+ of Vaccine Administration
  • January Wellness Corner
  • Introducing Percipio
  • State Business Transactions Disclosure Reports


Lawyers As Social Engineers: How Lawyers Should Use Their Social Capital To Achieve Economic Justice, Dana Thompson Jan 2021

Lawyers As Social Engineers: How Lawyers Should Use Their Social Capital To Achieve Economic Justice, Dana Thompson

Michigan Journal of Race and Law

The Michigan Business & Entrepreneurial Law Review (MBELR) has always strived to provide a platform for legal scholars, professionals, and students to publish business-related legal scholarship. Yet, little legal business scholarship focusing on the Black business community exists, despite the extraordinary impact that Black communities have in the U.S. business landscape. In a year of revolutionary social change, we are excited to feature in this special issue the work of Professor Dana Thompson, a Michigan Law alumna, in an effort to remedy this gap. Professor Thompson’s career, professional values, and day-to-day work demonstrate genuine, commanding, and inspiring commitment to social …


Systemic Racism, The Government’S Pandemic Response, And Racial Inequities In Covid-19, Ruqaiijah Yearby, Seema Mohapatra Jan 2021

Systemic Racism, The Government’S Pandemic Response, And Racial Inequities In Covid-19, Ruqaiijah Yearby, Seema Mohapatra

All Faculty Scholarship

During the COVID-19 pandemic, the federal and state governments have ignored racial and ethnic minorities’ unequal access to employment and health care that results in racial inequities in COVID-19 infections and deaths. In addition, they have enacted laws that further exacerbate these inequities. Consequently, many racial and ethnic minorities are employed in low-wage essential jobs that lack paid sick leave and health insurance. This lack of benefits causes them to go to work even when they are sick and prevents them from receiving appropriate medical treatment. As a result, racial and ethnic minorities have disproportionately been infected and died from …


Social Media Self-Regulation And The Rise Of Vaccine Misinformation, Ana Santos Rutschman Jan 2021

Social Media Self-Regulation And The Rise Of Vaccine Misinformation, Ana Santos Rutschman

All Faculty Scholarship

This essay examines the main characteristics and shortcomings of mainstream social media responses to vaccine misinformation and disinformation. Parts I and II contextualize the recent expansion of vaccine information and disinformation in the online environment. Part III provides a survey and taxonomy of ongoing responses to vaccine misinformation adopted by mainstream social media. It further notes the limitations of current self-regulatory modes and illustrates these limitations by presenting a short case study on Facebook—the largest social media vehicle for vaccine-specific misinformation, currently estimated to harbor approximately half of the social media accounts linked to vaccine misinformation. Part IV examines potential …


Lived Experience Of Geographically Dispersed Employees In The Absence Of Shared-Air Organizational Interactions, Tommie Ann Saragas Jan 2021

Lived Experience Of Geographically Dispersed Employees In The Absence Of Shared-Air Organizational Interactions, Tommie Ann Saragas

Walden Dissertations and Doctoral Studies

Prior to the COVID-19 pandemic, the number of employees choosing an off-site employment option increased annually. During COVID-19-related work-life modifications, many organizations worldwide were required to transition to a geographically dispersed, off-site workforce. While some individuals may enjoy the flexibility, convenience, and work-life balance of a geographically dispersed position, there is a need for organizations and employees to explore how workers perceive social support, experience feeling valued by and connected with leaders and team members and are impacted by technology and virtual interactions for those who work wholly off-site or at such a distance that face-to-face organizational interactions are not …


Neurodiversity And Workplace Social Capital Effects On Employee Attitudes And Intentions, Alice Edwards Jan 2021

Neurodiversity And Workplace Social Capital Effects On Employee Attitudes And Intentions, Alice Edwards

Walden Dissertations and Doctoral Studies

Neurodivergent employees have higher turnover rates than their neurotypical peers, andmuch remains unknown about how to improve their workplace experience. The purpose of this quantitative study was to examine the relationships between neurodiversity and workplace social capital on job satisfaction and turnover intent. Social cognitive career theory (SCCT) informed the study design. Working adults (N = 1,243) in the United States recruited using convenience sampling and MTurk participated through an anonymous online survey. Data analysis was conducted using three-way ANOVA and mediation. Significant three-way interactions were found between gender, job classification, and likelihood of having attention deficit hyperactivity disorder (ADHD) …


Camp Quest Leader Perspectives On Virtual Summer Camps Options During Pandemics, Timothy James Cummings Jan 2021

Camp Quest Leader Perspectives On Virtual Summer Camps Options During Pandemics, Timothy James Cummings

Walden Dissertations and Doctoral Studies

Summer overnight camping, a noteworthy childhood leadership growth opportunity, has suffered greatly because of the COVID-19 pandemic. In 2020, Camp Quest, Inc., a nonprofit organization that provides federated support services and governance to 12 independent nationwide camping organizations, was forced to cancel all of its in-person sessions. Hence, they now face an existential crisis that perhaps virtual camping sessions (i.e., camping activities performed remotely and online using computer equipment) can mitigate. Accordingly, this generic qualitative professional administrative study sought to understand and describe the perspectives of the camping leaders related to their experiences with virtual camping so that their mission …


Teachers’ Perceptions Of Literacy Instruction With Autistic Students During The Covid-19 Pandemic, Heather Ann Marzenski Jan 2021

Teachers’ Perceptions Of Literacy Instruction With Autistic Students During The Covid-19 Pandemic, Heather Ann Marzenski

Walden Dissertations and Doctoral Studies

Families and educators have voiced concerns about the literacy skills of students with autism spectrum disorder (ASD), and the COVID-19 pandemic has amplified the situation. Pandemic era studies have demonstrated the ramifications that students with ASD have faced, including regression of literacy skills, lower grades, lack of support services, and subpar instruction. Teachers' perceptions remained unexamined in the pandemic era studies. The purpose of this basic qualitative dissertation was to examine teachers’ perceptions about the materials and strategies used to deliver literacy instruction during the pandemic for students with ASD. The conceptual frameworks that underpinned this study were self-determination theory …


Online Medical Education And Examinations During Covid-19: Perspectives Of A Teaching Associate, Syed Mujtaba Baqir, Fatima Mustansir Jan 2021

Online Medical Education And Examinations During Covid-19: Perspectives Of A Teaching Associate, Syed Mujtaba Baqir, Fatima Mustansir

Department of Biological & Biomedical Sciences

The novel coronavirus disease 2019 (COVID-19) pandemic has not only challenged global health systems but also social, economic, and educational systems. In this short communication, our focus is on its impact on medical education in Pakistan. We discuss the structure of undergraduate medical education in Pakistan; and how it has evolved in the wake of COVID-19. We describe our role as teaching associates (TAs) at the Aga Khan University (AKU); and how it has enabled us to be a part of the transition to online medical education, with a specific focus on online examinations in medical schools.


Relationship Between Employee Perception Of Work Experience, Employee Perception Of Supervisors, And Intent To Leave, Kathryn F. Denning Jan 2021

Relationship Between Employee Perception Of Work Experience, Employee Perception Of Supervisors, And Intent To Leave, Kathryn F. Denning

Walden Dissertations and Doctoral Studies

Employee turnover can be costly; estimates for recruiting and training new hires are between 90% and 200% of the employee's annual salary. Understanding employee intent to leave is critical for managers to reduce turnover rates. Grounded in Herzberg’s two-factor model, the purpose of this quantitative correlational study was to examine the relationship between federal government agency employees' perception of their work experience, employee perception of supervisors, and employee intent to leave. Secondary data from 359,120 completed surveys from the 2020 Federal Employee Viewpoint Survey (FEVS) were analyzed. The results of the binary logistic regression were significant, X2 (359,120) = 17609.539, …


Influence Of Political Affiliation On Perceived Media Bias And Trustworthiness In The Covid-19 Pandemic, Tabitha Lamberth Jan 2021

Influence Of Political Affiliation On Perceived Media Bias And Trustworthiness In The Covid-19 Pandemic, Tabitha Lamberth

College of Graduate Studies: Theses & Dissertations

Partisanship and news source attribution may influence perceived media bias and trust in COVID-19 information. This study aimed to explore how the similarity liking effect relates to political identity and perceived credibility. Our main hypothesis was that individuals would find news sources that shared their political affiliation as more trustworthy than other news sources. To test our hypothesis, 216 undergraduate students participated in a study that measured participants’ trustworthiness of a news article with randomized source attribution from a liberal, conservative, and neutral source. A 2X3 ANOVA tested the relationship between our participants’ political affiliation, measured by the 12-item Social …


Teaching With Passion And Compassion In Challenging Times: A Narrative Inquiry Into Elementary Teachers' Experiences In Georgia, Erin Scroggs Jan 2021

Teaching With Passion And Compassion In Challenging Times: A Narrative Inquiry Into Elementary Teachers' Experiences In Georgia, Erin Scroggs

College of Graduate Studies: Theses & Dissertations

This study explores how teachers maintain their passion and compassion for teaching in spite of the impact of work-related challenges and subsequent obstacles upon their personal and professional lives. While much research has been conducted into teacher stress, very little has been done to connect the effects of stress on teachers’ health and passions for teaching. Abby, Nick, Passion, and Anna, four elementary school teachers from different areas, counties, schools, and school districts in the State of Georgia, participated in the study. Theoretically, I draw upon an array of works such as teaching towards freedom (Ayers, 2004, 2010, 2016), teachers …


Life In A Time Of Covid: A Mixed Method Study Of The Changes In Lifestyle, Mental And Psychosocial Health During And After Lockdown In Western Australians, Ranila Bhoyroo, Paola Chivers, Lynne Millar, Caroline Bulsara, Ben Piggott, Michelle Lambert, Jim Codde Jan 2021

Life In A Time Of Covid: A Mixed Method Study Of The Changes In Lifestyle, Mental And Psychosocial Health During And After Lockdown In Western Australians, Ranila Bhoyroo, Paola Chivers, Lynne Millar, Caroline Bulsara, Ben Piggott, Michelle Lambert, Jim Codde

Research outputs 2014 to 2021

Background: Since the beginning of the COVID-19 pandemic, the Western Australian government imposed multiple restrictions that impacted daily life activities and the social life. The aim of this study was to examine the effects of COVID-19 lockdown on the community’s physical, mental and psychosocial health. Methods: Approximately 2 months after a three-month lockdown, a cross-sectional study was opened to Western Australian adults for an 8-week period (25th August – 21 October 2020). Participants competed a 25-min questionnaire adapted from the Western Australia Health and Wellbeing Surveillance system. Participants provided information on their socio-demographic status, lifestyle behaviours, mental health, and psychosocial …


Recovery Agenda For Sustainable Development Post Covid-19 At The Country Level: Developing A Fuzzy Action Priority Surface, Meisam Ranjbari, Zahra S. Esfandabadi, Simone D. Scagnelli, Peer O. Siebers, Francesco Quatraro Jan 2021

Recovery Agenda For Sustainable Development Post Covid-19 At The Country Level: Developing A Fuzzy Action Priority Surface, Meisam Ranjbari, Zahra S. Esfandabadi, Simone D. Scagnelli, Peer O. Siebers, Francesco Quatraro

Research outputs 2014 to 2021

As a response to the urgent call for recovery actions against the COVID-19 crisis, this research aims to identify action priority areas post COVID-19 toward achieving the targets of the sustainable development goals (SDGs) within the 2030 Agenda for Sustainable Development launched by the United Nations (UN). This paper applies a mixed-method approach to map the post-COVID-19 SDGs targets on a fuzzy action priority surface at the country level in Iran, as a developing country, by taking the following four main steps: (1) using a modified Delphi method to make a list of the SDGs targets influenced by COVID-19; (2) …


Editorial: Covid-19, Corporate Governance, Sustainability, And The Post-Neoliberal World, Marie Dela Rama, Julie Crews Jan 2021

Editorial: Covid-19, Corporate Governance, Sustainability, And The Post-Neoliberal World, Marie Dela Rama, Julie Crews

Research outputs 2014 to 2021

Welcome to this special issue of Corporate Governance and Sustainability Review focusing on the impact of thecoronavirus (COVID-19) on societies and economies worldwide. The five papers in this special issue reflect the initial impact of the COVID-19 pandemic,in its first year,on corporate governance and sustainability. What is common throughout these papers is how the pandemic has created disequilibria for many organisations. The question continues to be posed as to the new forms of organising and managing as the world reorientates or pivots in a pandemic and post-pandemic world.


Vaccines Are Not Yet A Silver Bullet: The Imperative Of Continued Communication About The Importance Of Covid-19 Safety Measures, Zhaohui Su, Jun Wen, Dean Mcdonnell, Edmund Goh, Xiaoshan Li, Sabina Šegalo, Junaid Ahmad, Ali Cheshmehzangi, Yu-Tao Xiang Jan 2021

Vaccines Are Not Yet A Silver Bullet: The Imperative Of Continued Communication About The Importance Of Covid-19 Safety Measures, Zhaohui Su, Jun Wen, Dean Mcdonnell, Edmund Goh, Xiaoshan Li, Sabina Šegalo, Junaid Ahmad, Ali Cheshmehzangi, Yu-Tao Xiang

Research outputs 2014 to 2021

COVID-19 vaccines are by no means a silver bullet. With more COVID-19 vaccines expecting approval in the coming months, it is necessary to note that vaccine availability does not equate to vaccine accessibility, nor vaccine efficacy. Some research suggests that approximately 9 out of 10 individuals living in lower-income countries will not have access to COVID-19 vaccines until 2023 or later. For higher-income countries, such as the United States, the prevalence of vaccine hesitancy may further compound the situation. These insights combined, in turn, emphasize the fact that even though COVID-19 vaccines are becoming more available, safety measures (e.g., face …


Profile Of Immunoglobulin G N-Glycome In Covid-19 Patients: A Case-Control Study, Haifeng Hou, Huan Yang, Pengcheng Liu, Changwu Huang, Meng Wang, Yuejin Li, Mingsong Zhu, Jing Wang, Yuan Xu, Youxin Wang, Qingwei Ma, Dong Li, Pu Liao, Wei Wang Jan 2021

Profile Of Immunoglobulin G N-Glycome In Covid-19 Patients: A Case-Control Study, Haifeng Hou, Huan Yang, Pengcheng Liu, Changwu Huang, Meng Wang, Yuejin Li, Mingsong Zhu, Jing Wang, Yuan Xu, Youxin Wang, Qingwei Ma, Dong Li, Pu Liao, Wei Wang

Research outputs 2014 to 2021

Coronavirus disease 2019 (COVID-19) remains a major health challenge globally. Previous studies have suggested that changes in the glycosylation of IgG are closely associated with the severity of COVID-19. This study aimed to compare the profiles of IgG N-glycome between COVID-19 patients and healthy controls. A case-control study was conducted, in which 104 COVID-19 patients and 104 age- and sex-matched healthy individuals were recruited. Serum IgG N-glycome composition was analyzed by hydrophilic interaction liquid chromatography with the ultra-high-performance liquid chromatography (HILIC-UPLC) approach. COVID-19 patients have a decreased level of IgG fucosylation, which upregulates antibody-dependent cell cytotoxicity (ADCC) in …