Digital Commons Network^™

Enhanced Restoration Of Covid-19 Ct Scan Images Utilizing Advanced Wiener Filtering Techniques, Warqaa Shaher Alazawee, Marwa Subhi Ibrahim, Raghda Salam Al Mahdawi, Ali Albu-Rghaif, Ahmed Sabri Altaie

Iraqi Journal for Computer Science and Mathematics

COVID-19, caused by the SARS-CoV-2 virus, was declared a global pandemic by the World Health Organization (WHO) and rapidly spread worldwide from late 2019. While Reverse Transcription Polymerase Chain Reaction (RT-PCR) is the primary diagnostic tool, its sensitivity ranges from only 60% to 70%, leading to false negatives. Computed Tomography (CT) imaging has emerged as a valuable alternative for accurate diagnosis; however, the quality of CT images is often degraded by motion-induced blur and additive noise, particularly in children, individuals with mental health conditions, or those with phobias of CT scans. This study aims to enhance COVID-19 CT image quality …

Development And Transition In Crisis: The Impact Of The Covid-19 Pandemic On Division I College Athletes, Grace Kazmierski-Davie, Khalid Ballouli

Journal of Athlete Development and Experience

The aim of this study is to explore how Division I college athletes made meaning of their experiences during the onset of the COVID-19 pandemic in spring 2020. Though existing literature details various athlete transitions, there is limited knowledge about how athletes navigate unprecedented disruptions like a global pandemic. This qualitative study employed semi-structured interviews to gather in-depth data. The study included a diverse sample of 19 college athletes, ranging from freshmen to seniors, representing various sports and academic levels. Findings revealed that athletes employed diverse strategies to maintain readiness and mental sharpness, reflecting both proactive and reactive coping mechanisms. …

Full Issue: The International Undergraduate Journal Of Health Sciences, Volume 5, Issue 1, July 2025

International Undergraduate Journal of Health Sciences

Full Issue: The International Undergraduate Journal of Health Sciences, Volume 5, Issue 1, July 2025.

Abstracts From The 2025 Health Care Systems Research Network (Hcsrn) Annual Conference, St. Louis, Missouri, Health Care Systems Research Network

Journal of Patient-Centered Research and Reviews

The Health Care Systems Research Network (HCSRN) comprises 19 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate project findings, explore scientific collaborations, and share insights about population-based research practices that can measurably improve health and health care for all. The theme of this year’s conference was “Optimizing Collaborations to Advance Health in a Dynamic Research Landscape.” Abstracts presented at HCSRN 2025 are published in this issue supplement of the Journal of Patient-Centered Research and Reviews, the journal of record for …

Concurrent Dermatological Manifestations, Covid-19 Infection, And Mds/Rcmd-Rs: A Unique Case Report, Amenah S. Abdulkareem, Qutaiba M. Alawaad, Asaad Khalaf

Iraqi National Journal of Medicine

A 24-year-old male with refractory cytopenia with multilineage dysplasia and ring sideroblasts (MDS/RCMD-RS) who developed severe dermatological manifestations concurrent with COVID-19 infection. The patient exhibited complex vasculitic and purpuric skin lesions, which were hypothesized to result from COVID-19-induced endothelitis and vasculitis, exacerbated by underlying immune dysfunction from MDS. Despite treatment with EPO therapy, cyclosporin, and supportive care, the patient's condition deteriorated rapidly, leading to fatal respiratory failure. The report underscores the interplay between hematologic malignancies, immune dysregulation, and COVID-19, highlighting the potential for exacerbated dermatological and systemic complications in such patients. This case emphasizes the need for heightened vigilance and …

Mothers’ Plan To Protect Their Children From Covid-19 And Other Viral Illnesses, Miami Kadhum Yossif, Rehab Abdulwehab Jaafer

Iraqi National Journal of Medicine

Background: Mothers play a critical role in safeguarding the health and well-being of their children—a vulnerable population—particularly during outbreaks of infectious diseases. Aim: This study investigated the strategies employed by mothers to protect their children from COVID-19 and other viral illnesses. Methods: A cross-sectional study was conducted at the outpatient pediatric clinics of Basra Maternity and Children Hospital and Almawani Teaching Hospital, 118 mothers were enrolled from diverse backgrounds. Data was collected through structured interviews and a standardized questionnaire designed to assess maternal practices, attitudes, and experiences concerning the protection of their children. The key areas explored included hygiene practices, …

The Current And Future Burden Of Long Covid In The United States, Sarah M Bartsch, Kevin L Chin, Ulrich Strych, Danielle C John, Tej D Shah, Maria Elena Bottazzi, Kelly J O'Shea, Mckaylee Robertson, Colleen Weatherwax, Jessie Heneghan, Marie F Martinez, Allan Ciciriello, Sarah Kulkarni, Kavya Velmurugan, Alexis Dibbs, Sheryl A Scannell, Yanhan Shen, Denis Nash, Peter J Hotez, Bruce Y Lee

Faculty, Staff and Students Publications

Background: Long coronavirus disease (COVID), which affects an estimated 44.69-48.04 million people in the United States, is an ongoing public health concern that will persist as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread.

Methods: We developed a computational simulation model representing the clinical course, health effects, and associated costs of a person with long COVID.

Results: Simulations show that the average total cost of a long COVID case can range from $5084-$11 646 (assuming symptoms only last 1 year) with 92.5%-95.2% of these costs being productivity losses. Therefore, the current number of long COVID cases could cost …

Maslow Meets Healthcare: Optimizing Cna Training And Well-Being Through Hierarchical Needs During Covid-19, Jose D. Martinez Herrera

Online Journal for Workforce Education and Development

This study investigates the relationship between motivation, as defined by Maslow’s Hierarchy of Needs, and the performance of Certified Nurse Aides (CNAs) on the Illinois Nurse Aide Competency Evaluation Exam (INACE), with a focus on the impact of gender and motivation during the COVID-19 pandemic. CNAs must meet stringent certification standards, but recent declines in enrollment and increased demands on healthcare workers, exacerbated by the pandemic, necessitate a deeper exploration of factors influencing their success. This research employs a quantitative, non-experimental correlational design, analyzing data from 411 CNA students sampled from community colleges in Illinois. The study examines motivation across …

Impact Of Telehealth On Outcomes In Daily Practice, Shannon Stuebs

Theses and Dissertations

While telepsychology has existed in various forms for years and has been researched since the 1960s (Abrams, 2020), it was not until the COVID-19 pandemic that telepsychology started to be widely used. Prior to the COVID-19 pandemic, one study found that psychologists conducted only around 7% of their work via telepsychology, a number that jumped to over 85% in response to COVID-19 (Pierce, Perrin, Tyler, et al., 2020). While there has been a significant increase in the research exploring the efficacy of telehealth since the start of the pandemic (Lin et al., 2022), further research regarding long-term impacts and specific …

High-Affinity Cd16a Polymorphism Associated With Reduced Risk Ofsevere Covid-19, Anita E Qualls, Tasha Tsao, Irene Lui, Shion A Lim, Yapeng Su, Ernie Chen, Dylan Duchen, Holden T Maecker, Seunghee Kim-Schulze, Ruth R Montgomery, Florian Krammer, Charles R Langelier, Ofer Levy, Lindsey R Baden, Esther Melamed, Lauren Ir Ehrlich, Grace A Mccomsey, Rafick P Sekaly, Charles B Cairns, Elias K Haddad, Albert C Shaw, David A Hafler, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Ana Fernandez-Sesma, Viviana Simon, Monica Kraft, Christian Bime, Carolyn S Calfee, David J Erle, Joanna Schaenmann, Al Ozonoff, Bjoern Peters, Steven H Kleinstein, Alison D Augustine, Joann Diray-Arce, Patrice M Becker, Nadine Rouphael, Impacc Network, Jason D Goldman, Daniel R Calabrese, James R Heath, James A Wells, Elaine F Reed, Lewis L Lanier, Harry Pickering, Oscar A Aguilar

Faculty, Staff and Students Publications

CD16A is an activating Fc receptor on NK cells that mediates antibody-dependent cellular cytotoxicity (ADCC), a key mechanism in antiviral immunity. However, the role of NK cell-mediated ADCC in SARS-CoV-2 infection remains unclear, particularly whether it limits viral spread and disease severity or contributes to the immunopathogenesis of COVID-19. We hypothesized that the high-affinity CD16AV176 polymorphism influences these outcomes. Using an in vitro reporter system, we demonstrated that CD16AV176 is a more potent and sensitive activator than the common CD16AF176 allele. To assess its clinical relevance, we analyzed 1,027 patients hospitalized with COVID-19 from the Immunophenotyping Assessment in a COVID-19 …

Rapid Access Chest Pain Assessment Clinic: An Australian Virtual Care Experience, Marwan Shawki, Thalys Sampaio Rodrigues, Hussein Al-Fiadh, Karen Sanders Mnursing, Ali H. Al-Fiadh

Journal of the Saudi Heart Association

Background: The Rapid Access Chest Pain Assessment Clinic (RACPAC) streamlines the evaluation of low to intermediate-risk chest pain patients, reducing hospitalisation and healthcare costs. However, there is limited data on the virtual model of care for RACPAC.

Aim: We sought to evaluate the structure, cost-effectiveness, and imaging modalities performance of face-to-face and virtual RACPAC in an Australian setting.

Methods:A retrospective analysis of patients attending the RACPAC within a large Australian quaternary hospital between 2012 and 2021. We described the clinic parameters and imaging modality utilisation with parametric and non-parametric descriptive statics. Patterns of diagnostic modality utilisation were assessed with …

Washu Epigenome Browser Update 2025, Chanrung Seng, Shane Liu, Wenjin Zhang, Xiaoyu Zhuo, Daofeng Li, Ting Wang

2020-Current year OA Pubs

The WashU Epigenome Browser (https://epigenomegateway.wustl.edu/) is a web-based tool for exploring genomic data and providing visualization, investigation, and analysis of epigenomic datasets. Since its 2018 update, the redesigned user interface and newly developed features have enhanced how investigators interact with both the Browser and the extensive genomic data it hosts. The rapid evolution of the JavaScript ecosystem has presented new challenges and opportunities in maintaining and developing the WashU Epigenome Browser. In this update, we present a completely rewritten codebase. This new codebase minimizes the use of external libraries whenever possible, resulting in a significantly smaller code bundle size after …

Diagnosis Of Covid-19 And Viral Pneumonia With Chest X-Ray Images Using Resnet-34, Sudhir Anakal, Krishna Prasad K, Chandrashekhar Uppin, Dileep Kumar M

Iraqi Journal for Computer Science and Mathematics

COVID-19 is a highly contagious viral infection that primarily affects the respiratory system, causing symptoms such as high fever, cough, and severe respiratory distress. Early detection of the disease is of utmost importance to control the spread and severity. Common diagnostic methods include Reverse Transcription Polymerase Chain Reaction (RT-PCR), antigen tests, chest X-rays, and computed tomography (CT) scans. Similarly, viral pneumonia, another severe lung infection, leads to fluid or pus accumulation in the lungs, causing symptoms such as chest pain, fatigue, excessive sweating, and nausea. The elderly and young children are particularly vulnerable to severe complications. Similarly, viral pneumonia, another …

Retracted: A Novel Benchmarking Framework For Selecting The Best Deep Learning Model Diagnosing Covid-19 Based On New Development For Dual Mcdm Methods, Mahmood M. Salih, Yousif Raad Muhsen, M.A. Ahmed, Reem D. Ismael, Moceheb Lazam Shuwandy, Z.T. Al-Qaysi

Iraqi Journal for Computer Science and Mathematics

COVID-19 was diagnosed using deep learning models by a group of studies. Evaluating and benchmarking these models are essential to achieving the most suitable model for diagnosing coronavirus. Objective: In this investigation, we offer an inclusive valuation of several deep learning models to detect the maximum appropriate and active model which gratifies doctors' requirements and assessment criteria. Method: This study combines Fuzzy decision by the opinion score method (FDOSM) and Fuzzy-Weighted Zero-Inconsistency (FWZIC). According to the advantage of Trapezoidal Intuitionistic fuzzy, we developed FWZIC into Trapezoidal Intuitionistic fuzzy named (TrIF-FWZIC) for weighting criteria and FDOSM into Trapezoidal Intuitionistic fuzzy FDOSM …

Covid-19-Related Beliefs And Dietary Behaviors Of American Undergraduate Students Vary By Race Via The Lens Of The Health Belief Model, Doreen Liou, Jong Min Lee

Department of Nutrition and Food Studies Scholarship and Creative Works

The COVID-19 pandemic caused immense physical disruptions, affecting young adults in the U.S. The Health Belief Model is a social psychological framework that predicts the likelihood of adopting health behavior. The purpose of this research is to investigate COVID-19-related health beliefs and dietary behaviors among undergraduate students during the pandemic. Using convenience sampling, a cross-sectional survey was completed by 304 individuals at a New Jersey state university. Survey data included the frequency of COVID-19 prevention behaviors (e.g., wearing an indoor mask, handwashing), and consumption of fruit and vegetables. The Health Belief Model constructs measured perceived susceptibility to COVID-19, severity, benefits, …

The Influence Of Human Presence And Footprint On Animal Space Use In Us National Parks, Kaitlyn M. Gaynor, Forest P. Hayes, Kezia Manlove, Nathan Galloway, John F. Benson, Michael J. Cherry, Rolf O. Peterson, Sarah Hoy, John Vucetich, Et Al.

Michigan Tech Publications

Given the importance of protected areas for biodiversity, the growth of visitation to many areas has raised concerns about the effects of humans on wildlife. In 2020, the COVID-19 pandemic led to temporary closure of national parks in the United States, offering a pseudonatural experiment to tease apart the effects of permanent infrastructure and transient human presence on animals. We compiled GPS tracking data from 229 individuals of 10 mammal species in 14 parks and used third-order hierarchical resource selection functions to evaluate the influence of the human footprint on animal space use in 2019 and 2020. Averaged across all …

Analyzing The Impact Of Covid-19 On The Achievement Gap: The State Of Education In Minnesota From A Superintendent's Perspective, Jillian Stockmo Chapman

School of Education and Leadership Student Capstone Theses and Dissertations

The COVID-19 pandemic disrupted education systems globally, nationally and in Minnesota. This created difficulties but also opportunities for innovation, especially for students most impacted by educational inequities. This dissertation investigates the impacts of the pandemic through three related research questions: (1) In what ways did COVID-19 impact Minnesota’s achievement gap? (2) How do superintendents describe the impact of COVID-19 on their districts and their districts’ disparities? And (3) What have been some of the most innovative opportunities districts’ have explored to recoup learning loss emerging from the COVID-19 crisis?

Using a qualitative research design that is grounded in a transformative …

The Relationship Between The Light And Dark Triads Of Personality, Covid-19 Threat, And Covid-19 Vaccine Status In College Students, Alyssa M. Howard, Terry F. Pettijohn Ii

Psychology

The rapid spread of the COVID-19 pandemic in the United States was due, or at least in part, to the resistance to health guidelines, minimal to no safety measures implemented by nearly half the U.S. citizens, and, to a lesser extent, the initial lack of understanding into the pathogenic mode of transmission. The present study examined links between the Dark (i.e.., narcissism, psychopathy, Machiavellianism) and Light (i.e.., compassion, empathy, altruism) Triad of personality traits, the perceived threat level of COVID-19, and COVID-19 vaccine uptake in an undergraduate college sample (N = 147). The study found no statistically significant differences in …

Pengaruh Vaksinasi Covid-19 Terhadap Kesehatan Dan Kondisi Ekonomi Masyarakat Di Indonesia, Ayu Lestari, Fauziah Zen

Jurnal Ekonomi dan Pembangunan Indonesia

The COVID-19 vaccination is considered crucial for controlling the pandemic and accelerating economic recovery. However, empirical evidence on the impact of vaccination on health and the economy at the district/city level in Indonesia remains limited. This study aims to analyze the impact of vaccination on health outcomes and economic conditions. The methodology used is a fixed effect model with monthly panel data on vaccination and health outcomes (positivity rate and recovery), as well as annual data on per capita expenditure in 514 districts/cities from January 2021 to December 2022. The results show that the first dose of vaccination significantly reduces …

An Exploration Of The Effect Of Covid Restrictions On Maternity Care In Uganda, Hellen Kyakuwaire, Grace Edwards, Ahmed Mohammed Sarki

Journal of Asian Midwives (JAM)

Background: Uganda responded aggressively to the worldwide spread of COVID-19 by imposing a total lockdown, which forbade movement of the whole population, including pregnant women and other vulnerable groups. This phenomenological study explored pregnant women’s experiences during the total lockdown in Uganda and identified factors that influenced the quality of healthcare for pregnant women during the lockdown.
Methods: Thirty-two newly delivered women were selected across a wide geographical area to represent rural and urban areas. The sample was selected from women who had given birth at the selected health facilities from March 18, 2020, to April 30, 2020. …

The Impact Of The Covid-19 Pandemic On Maternity Care Services: Lived Experiences Of Midwives In Indonesia, Mergy Gayatri, Oluwadamilare Akingbade, Indhar Wahyu Wira Harjo, Adepegba Folasade Rebecca, Salako Faith Adebola

Journal of Asian Midwives (JAM)

Background: There have been fundamental changes in global maternity care in response to the COVID-19 pandemic across the globe. However, there are limited studies in Indonesia that have explored the changes experienced by midwives in various health facilities during the COVID-19 pandemic.
Method: A qualitative phenomenological study was conducted among midwives with at least three years of clinical experience in midwifery practice and practicing at different levels of healthcare. Semi-structured interviews were conducted through WhatsApp or Phone calls, as face-to-face interviews were impossible during the pandemic. Data were analyzed using thematic analysis.
Results: In total, 24 midwives …

Determinants Of Bangladeshi Banking Inefficiency: Do Non-Performing Loans And Basel Iii Affect Banking Inefficiency?, Mohammad Abdul Matin Chowdhury, S. M. Shamsul Alam, Wan Rohaida Wan Husain, Rafikul Islam, Anwar Hossain

DLSU Business & Economics Review

The efficiency of commercial banking is a crucial determinant of the longevity of the financial system. High credit risk is a significant feebleness that leads to high non-performing loans (NPLs), which reduce banking efficiency in any economy. In this context, this study aims to identify the determinants of banking inefficiency in Bangladesh. The Data Envelopment Analysis (DEA) technique was employed to measure banking efficiency, whereas TOBIT regression was performed to identify the determinants of inefficiency of 38 commercial banks from 2016–2022. Findings demonstrated size, ownership structure and orientation, capital structure regulations (BASEL III), GDP growth, and inflation as significant determinants …

Exploring Covid-19 Vaccination Behavior: A Cross-Country Study Among Pregnant And Postpartum Women In Brazil, Ghana, Kenya, And Pakistan, Rupali Limaye, Berhaun Fesshaye, Emilly Miller, Prachi Singh, Saleem Jessani, Muhammad Asim, Ferdinand Okwaro, Caroline Badzi, Emefa Amoah, Marleen Temmerman

Centre of Excellence in Women and Child Health

Pregnant women infected with SARS-CoV2 are more likely to be hospitalized and require ventilation, compared to non-pregnant women. Although the development of the COVID-19 vaccine was regarded as a scientific breakthrough among many, the pace of development in combination with delayed and unclear recommendations for maternal vaccination led to slower vaccine uptake among this population. We explored the decision-making process for COVID-19 vaccination among pregnant and postpartum women in four countries: Brazil, Ghana, Kenya, and Pakistan through 201 in-depth interviews. A grounded theory approach was used for analysis, and a socio-ecological framework was used to synthesize emerging themes. Four levels …

Covid-19 Vaccine Attitudes And Behaviors Among Pregnant Women In Nairobi, Kenya With Diverse Socio-Economic And Educational Backgrounds, Jessica Schue, Ferdinand Okwaro, Ingrid Gichere, Daizy Cherono, Mandeep Sura, Emily Miller, Berhaun Fesshaye, Prachi Singh, Grace Belayneh Belayneh, Rupali Limaye, Marleen Temmerman

Centre of Excellence in Women and Child Health

Introduction

Methods

Placental Transfer Of Sars-Cov-2 Antibodies In Mother-Neonate Pairs: A Prospective Nested Cohort Study, Alex Mugo, Angela Koech, Liberty Cantrell, Moses Mukhanya, Isaac Mwaniki, Joseph Mutunga, Merryn Voysey, Rachel Craik, Marleen Temmerman, Geoffrey Omuse

Centre of Excellence in Women and Child Health

Background: Newborns depend on the transfer of IgG across the placenta to acquire protection against pathogens. We assessed the placental transfer of SARS-CoV-2 antibodies, primarily derived from infection, from seropositive pregnant women enrolled in a pregnancy cohort in Kilifi, Kenya.

Methods :The study was nested within a prospective observational multi-country cohort study. All available paired maternal delivery and cord blood samples were selected. Maternal sera were tested for SARS-CoV-2 receptor binding domain (RBD) IgM/IgG total antibodies using the Wantai assay. For positive samples, maternal and corresponding cord blood samples were tested for SARS-CoV-2 IgG antibodies against the spike (anti-spike) and …

Placental Transfer Of Sars-Cov-2 Antibodies In Mother-Neonate Pairs: A Prospective Nested Cohort Study, Alex Mugo, Angela Koech, Liberty Cantrell, Moses Mukhanya, Isaac Mwaniki, Joseph Mutunga, Merryn Voysey, Rachel Craik, Peter Dadelszen, Marleen Temmerman, Geoffrey Omuse

Centre of Excellence in Women and Child Health

Background

Newborns depend on the transfer of IgG across the placenta to acquire protection against pathogens. We assessed the placental transfer of SARS-CoV-2 antibodies, primarily derived from infection, from seropositive pregnant women enrolled in a pregnancy cohort in Kilifi, Kenya.

Methods

The study was nested within a prospective observational multi-country cohort study. All available paired maternal delivery and cord blood samples were selected. Maternal sera were tested for SARS-CoV-2 receptor binding domain (RBD) IgM/IgG total antibodies using the Wantai assay. For positive samples, maternal and corresponding cord blood samples were tested for SARS-CoV-2 IgG antibodies against the spike (anti-spike) and …

A Mixed Methods Study Exploring The Lived Experience Of Shared Trauma In Psychiatric Nurses During Covid-19, April Lynne Hutto

Theses and Dissertations

Introduction: Psychiatric nurses (PNs) had a unique lived experience of shared trauma (ST) during the COVID-19 pandemic. These nurses experienced the same traumatic event, COVID-19, with associated trauma symptoms as their patients. This mixed methods study aims to triangulate data on ST in PNs using a quantitative and qualitative study. Methods: PN (N=24) completed a semi-structured interview during the summer and fall of 2024. A quantitative study PN (N=552) in spring 2023, using the Shared Trauma and Professional Posttraumatic Growth (STPPG) inventory, was completed with descriptive and inferential statistics using SAS 9.4. A thematic analysis of the interviews was completed …

Adtnorm: Robust Integration Of Single-Cell Protein Measurement Across Cite-Seq Datasets, Ye Zheng, Daniel P Caron, Ju Yeong Kim, Seong-Hwan Jun, Yuan Tian, Florian Mair, Kenneth D Stuart, Peter A Sims, Raphael Gottardo

Faculty, Staff and Student Publications

Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq) enables paired measurement of surface protein and mRNA expression in single cells using antibodies conjugated to oligonucleotide tags. Due to the high copy number of surface protein molecules, sequencing antibody-derived tags (ADTs) allows for robust protein detection, improving cell-type identification. However, variability in antibody staining leads to batch effects in the ADT expression, obscuring biological variation, reducing interpretability, and obstructing cross-study analyses. Here, we present ADTnorm, a normalization and integration method designed explicitly for ADT abundance. Benchmarking against 14 existing scaling and normalization methods, we show that ADTnorm accurately aligns populations …

High-Frequency, At-Home Monitoring Of Drug Safety And Tolerability In Clinical Trials: Results From Studies Of Fluvoxamine For Covid-19 Treatment, Eric J Lenze, Madeline Nykamp, J Philip Miller, Angela Stevens, Julia Schweiger, Torie Gettinger, Michael Yingling, Yi Zhang, Ginger E Nicol, Charles F Zorumski, Angela M Reiersen

2020-Current year OA Pubs

Clinical trials are increasingly using remote monitoring techniques at the patient's home. We conducted a secondary analysis of remote safety and tolerability monitoring from two fully-remote clinical trials that tested fluvoxamine for the acute treatment of COVID-19. Both trials assessed pulse and blood pressure daily, and one study assessed symptoms daily via Ecological Momentary Assessment. On average, patients provided data on vital signs on 93% of the study days and provided data on side effects on 81% of the study days. With respect to safety, patients taking fluvoxamine had reduced pulse rate compared to placebo, with the greatest difference-5 points-at …

Clinical Evaluation Of The Healgen Rapid Covid-19 Antigen Test As A Point-Of-Care Diagnostic Tool, Stephen A Young, Hua Zhang, Jose Rodriguez, David Mishkin, Ward Paine, Li Seyfried, Latisha Hargrove, Dennis L Broyles, Chermaen Lindberg, Anurag Purushothaman, Stacey House

2020-Current year OA Pubs

BACKGROUND: Development of readily available Rapid COVID-19 Antigen tests essential for promptly identifying SARS-CoV2 infection and preventing its spread.

METHODS: This study evaluated the clinical performance of the Healgen Rapid COVID-19 antigen test as a point-of-care diagnostic tool with 806 evaluable subjects who were within 6 days post-symptom onset. The results from the Healgen test were compared to the results from Emergency Use Authorization (EUA) approved SARS-CoV-2 RT-PCR tests.

RESULTS: Out of the 806 evaluable subjects, 140 tested positive and 640 tested negative for SARS-CoV-2 with the Healgen COVID-19 test, showing good agreement with the EUA RT-PCR results. There were …