Digital Commons Network^™

Donepezil-Associated Survival Benefits Among Alzheimer’S Disease Patients Are Retained But Not Enhanced During Covid-19 Infections, Elizabeth A. Edmiston, Taissa A. Bej, Brigid Wilson, Robin L.P. Jump

Faculty Scholarship

Background and Aim: Donepezil is a front-line treatment for Alzheimer’s disease. Donepezil treatment is associated with decreased risk of all-cause mortality. Specific protection is observed in pneumonia and cardiovascular disease. We hypothesized that donepezil treatment would improve mortality among Alzheimer’s patients following infection with COVID-19. The objective of this study is to assess the influence of ongoing donepezil treatment on survival in Alzheimer’s disease patients after polymerase chain reaction (PCR)-confirmed COVID-19 infection. Methods: This is a retrospective cohort study. We conducted a national survey of Veterans with Alzheimer’s disease to assess the influence of ongoing donepezil treatment on survival in …

Smoking Status, Nicotine Medication, Vaccination, And Covid-19 Hospital Outcomes: Findings From The Covid Ehr Cohort At The University Of Wisconsin (Cec-Uw) Study, Thomas M Piasecki, Li-Shiun Chen, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Available evidence is mixed concerning associations between smoking status and COVID-19 clinical outcomes. Effects of nicotine replacement therapy (NRT) and vaccination status on COVID-19 outcomes in smokers are unknown.

METHODS: Electronic health record data from 104 590 COVID-19 patients hospitalized February 1, 2020 to September 30, 2021 in 21 U.S. health systems were analyzed to assess associations of smoking status, in-hospital NRT prescription, and vaccination status with in-hospital death and ICU admission.

RESULTS: Current (n = 7764) and never smokers (n = 57 454) did not differ on outcomes after adjustment for age, sex, race, ethnicity, insurance, body mass …

Covid-19 Pandemic: Lived Experiences Of Teachers Supporting Students’ Socialemotional Learning Needs Upon Returning To Face-To-Face Instruction, Valerie Cover

Dissertations

Purpose: The purpose of this qualitative phenomenological study was to explore the lived experiences of San Bernardino County elementary school teachers in supporting students' social-emotional learning needs upon returning to face-to-face instruction after the COVID-19 pandemic.

Methodology: This phenomenological study identified and described San Bernardino County elementary school teachers' experiences supporting students' social-emotional needs upon returning to face-to-face instruction after the COVID-19 pandemic. Participants were purposively chosen based on specific criteria of working in a public kindergarten through sixth grade setting within San Bernardino County. The participants answered 15 semi-structured questions. The transcribed data collected by the researcher during the …

Immigration Policy After Covid-19 And Cultural Resistance At The U.S.-Mexico Border, Grace Ayres-Doyle

Senior Theses

What I examine here is how the global COVID-19 pandemic altered asylum and refugee responsibility among Global North countries. In particular, I look at cultural responses to restrictive pandemic policies which speak to the level of intensity of the current humanitarian crisis at the United States southern border with Mexico. The US-Mexico border functions well as a case study because of its highly publicized and discussed nature, along with the strong influence held by the US over the rest of the world. The cultural moment surrounding Title 42 and other pandemic policies represents a shift in public recognition of the …

Impact Of The Covid-19 Pandemic On Stress And Burnout Related Experiences Of The Infection Preventionists In The Greater Houston Area, Tawanna Mcinnis-Cole

MUSC Theses and Dissertations

Objective: With many studies revealing that the pandemic created stress and burnout for physicians and nurses, these same stressors could have created mental and emotional challenges for the Infection Prevention staff at healthcare institutions. Efforts are needed to better understand the stress, anxiety, and burnout-related experiences that the pandemic created for these team members who worked in the greater Houston area between March 2020-September 2022.

Methods: This qualitative study used focus group sessions to obtain data. Two sessions were held in person and two sessions were hosted virtually. All sessions were audio recorded and transcribed. The transcripts were coded using …

Toll-Like Receptors 2, 4, And 9 Modulate Promoting Effect Of Copd-Like Airway Inflammation On K-Ras-Driven Lung Cancer Through Activation Of The Myd88/Nf-ĸb Pathway In The Airway Epithelium, Walter V Velasco, Nasim Khosravi, Susana Castro-Pando, Nelly Torres-Garza, Maria T Grimaldo, Avantika Krishna, Michael J Clowers, Misha Umer, Sabah Tariq Amir, Diana Del Bosque, Soudabeh Daliri, Maria Miguelina De La Garza, Marco Ramos-Castaneda, Scott E Evans, Seyed Javad Moghaddam

Faculty, Staff and Student Publications

INTRODUCTION: Toll-like receptors (TLRs) are an extensive group of proteins involved in host defense processes that express themselves upon the increased production of endogenous damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) due to the constant contact that airway epithelium may have with pathogenic foreign antigens. We have previously shown that COPD-like airway inflammation induced by exposure to an aerosolized lysate of nontypeable

METHODS: In the present study, we have dissected the role of TLRs in this process by knocking out TLR2, 4, and 9 and analyzing how these deletions affect the promoting effect of COPD-like airway inflammation on …

Balancing The Drinking Act: A Grounded Theory Of Youth Drinking, Policy And Covid-19 In Botswana, Tebogo Sebeelo

The Qualitative Report

Stakeholder and consumer participation is generally seen as a critical part of effective alcohol policy making as it has a direct impact on policy implementation. In the advent of COVID-19, the views and experiences of stakeholders and consumers were integral to how countries responded to the virus. The involvement of alcohol stakeholders and consumers raises critical questions about policy making practices. Using Grounded Theory (GT) methods amongst 20 drinkers and six alcohol stakeholders, I examined the views and experiences of stakeholders and alcohol consumers in Botswana during COVID-19. I identified two interrelated core categories of Balancing the Drinking Act and …

The Application Of Policy Theory To Covid-19 Stimulus Checks, Michael Mchenry

The Gettysburg Journal for Public Policy

This paper analyzes COVID-19 stimulus checks in a variety of public policy frameworks. Punctuated equilibrium theory is useful in explaining the development and implementation of this policy action. Narrative policy framework provides context for how the stimulus checks were perceived by the public and how that perception influences future policy. The stimulus check policy is also analyzed from the perspective of both a rationalist and critical policy analyst. These three policy frameworks interact with one another to create a feedback loop that informs future crisis policy.

Nikita Jain, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Nikita Jain is an award-winning independent journalist based in India. She has covered various issues catering to human rights, conflict, gender, crime, health, education, and the environment. Her work has been published on national and international platforms including The Wire, Women’s Media Centre, The Diplomat, New Internationalist, and The News Lens, among others.

Jain published hundreds of articles during COVID-19 to document the impact of the pandemic on hospitals, patients, and minority groups in India. Her reporting challenged the government-controlled mainstream media that downplayed the severity of the pandemic. She had to dispute government propaganda, negotiate reporting access, and endure …

Blockchain-Enabled Immutable, Distributed, And Highly Available Clinical Research Activity Logging System For Federated Covid-19 Data Analysis From Multiple Institutions, Tsung-Ting Kuo, Anh Pham, Maxim E Edelson, Jihoon Kim, Jason Chan, Yash Gupta, Lucila Ohno-Machado

Faculty, Staff and Student Publications

OBJECTIVE: We aimed to develop a distributed, immutable, and highly available cross-cloud blockchain system to facilitate federated data analysis activities among multiple institutions.

MATERIALS AND METHODS: We preprocessed 9166 COVID-19 Structured Query Language (SQL) code, summary statistics, and user activity logs, from the GitHub repository of the Reliable Response Data Discovery for COVID-19 (R2D2) Consortium. The repository collected local summary statistics from participating institutions and aggregated the global result to a COVID-19-related clinical query, previously posted by clinicians on a website. We developed both on-chain and off-chain components to store/query these activity logs and their associated queries/results on a blockchain …

Denise Hruby, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Denise Hruby from Vienna, Austria, is an award-winning journalist, writer, and National Geographic Explorer focusing on the climate and biodiversity crises and politics. Her work has appeared in The New York Times, National Geographic Magazine, The Washington Post, and CNN, among many others. She has won multiple international awards for environmental reporting and feature writing and numerous fellowships and grants. Throughout her career, Denise has reported from more than 25 countries, including the war in Ukraine, terror attacks in Austria, and conflicts in South Sudan among many other national and international events. Before relocating to Vienna in 2018, Denise worked …

Improving Patient Safety For Surgical Clearance: A Preop One Stop Shop, Anna Benedictos

Doctor of Nursing Practice (DNP) Projects

Problem: Medical clearance is required for patients scheduled for surgery, also known as “patient optimization.” Ineffective and inefficient patient optimization is a major contributor to surgery postponements, procedure cancellations, and patient dissatisfaction.

Context: Ambulatory care clinics often lack resources to medically clear patients prior to scheduled surgery. Poor surgical optimization continues to occur on the same day of surgery, resulting in case cancellation or delay in a suburban, 169 bed community hospital with 9 operating rooms and approximately 500 surgical procedures per month.

Interventions: A nurse-led PreOp One Stop Shop (POSS) utilized a standardized checklist to perform preoperative surgical assessment. …

Jess Dipierro Obert, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Jess DiPierro Obert reported on COVID-19 from Haiti. She is an investigative visual journalist, producer, and filmmaker who splits her time between Mexico City, Brooklyn, and Haiti. She focuses on solution-based storytelling around women and abortion, human rights, identity, and mental health in Latin America and the Caribbean, and the U.S. Her byline has appeared in Buzzfeed News, The Guardian, Reuters, Al Jazeera English, the New York Times and others.

DiPierro Obert did investigative reporting on vaccine hesitancy and mental health issues in Haiti during the pandemic, which increased public awareness and conversation about COVID-related issues. In this interview, she …

April Zhu, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

April Zhu is a freelance journalist based in Kenya. Her work focuses on gender, urban inequality, and the Chinese diaspora in Kenya. She is a senior editor at Guernica Magazine where she edits interviews and produces a podcast “Until Everyone is Free”. Her work has appeared in The New York Review of Books Daily, Foreign Policy, The Baffler Magazine, The South China Morning Post Magazine, VOA News, and others.

Zhu's COVID reporting helped people understand the systematic issues in the healthcare system in Africa. She recalled the early lockdowns in Kenya, government responses, and police violence. She criticized Sinophobia and …

Post-Pandemic Digital Experiences & Attitudes Among Adult Immigrant Esol Learners, Lacey D. Goodloe

Master's Theses

This mixed-methods study considers the current reality of the “digital divide” as experienced by adult immigrant ESOL learners following the COVID-19 pandemic lockdown period. Although prior research often assumes foreign-born individuals to have lower rates of access, skills and motivation to engage with technology, or to lack it altogether, this study seeks to contribute a more realistic picture which encompasses the full diversity of digital experiences among the foreign-born population. The review of the literature first covers two levels of the digital divide that often evince socioeconomic disparities: primarily access, skills and usage; and more recently, attitudes and motivation. Then, …

Lenora Chu, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Lenora Chu is a journalist, public speaker, and media strategist with over 15 years of experience in the U.S., China, and Europe. Now based in Berlin, Germany, she covers Europe for the nonprofit news organization Christian Science Monitor. A long-time journalist, Chu focuses on the intersection of politics, education, and culture in her reporting. Her work has appeared in the Wall Street Journal, New York Times, and New York magazine, among others. Her book, “Little Soldier” won the “Best Education Book of 2017” among other awards. In 2019, she was named to the Public Intellectuals Program of the National Committee …

Frankie Huang, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Frankie Huang from the United States is a freelance writer, editor, strategist, and illustrator. She writes about culture and food, and she is interested in intersectional feminism, diaspora Asian American identity, social justice, storytelling, the hybrid of translation and creation, and beauty in all its forms. Her work has been published in The Atlantic, The New York Times, The Guardian, Foreign Policy, and 1843 Magazine, among many others.

Huang published a few opinion pieces based on her experience in Shanghai in the early days of the pandemic and then returning to the U.S. In this interview, she recalled her journey …

The Evolution Of Primary Care Telehealth Disparities During Covid-19: Retrospective Cohort Study, Rachel D'Amico, Patrick M Schnell, Randi Foraker, J Nwando Olayiwola, Daniel E Jonas, Seuli Bose Brill

2020-Current year OA Pubs

BACKGROUND: Telehealth has become widely used as a novel way to provide outpatient care during the COVID-19 pandemic, but data about telehealth use in primary care remain limited. Studies in other specialties raise concerns that telehealth may be widening existing health care disparities, requiring further scrutiny of trends in telehealth use.

OBJECTIVE: Our study aims to further characterize sociodemographic differences in primary care via telehealth compared to in-person office visits before and during the COVID-19 pandemic and determine if these disparities changed throughout 2020.

METHODS: We conducted a retrospective cohort study in a large US academic center with 46 primary …

The Long-Term Psycho-Social Impact Of The Pandemic On People With Intellectual Disability And Their Carers, Alexandra Gabrielsson, Meissam Moghaddassian, Indermeet Sawhney, Sophie Shardlow, Samuel Tromans, Paul Bassett, Rohit Shankar

Peninsula Medical School

Background: People with intellectual disabilities (PWID) are at six times higher risk of death due to COVID-19. To mitigate harm, as a high-risk group, significant social changes were imposed on PWID in the UK. Alongside these changes, the uncertainty of the pandemic influence, caused PWID and their carers to encounter significant stress. The evidence of the pandemic’s psycho-social impact on PWID originates mainly from cross-sectional surveys conducted with professionals and carers. There is little research on the longitudinal psycho-social impact of the pandemic from PWID themselves. Aims: To examine the long-term psycho-social impact of the pandemic on PWID. Methods: A …

Beyond Response: Reimagining The Legal Academy's Role In Disaster Recovery And Preparedness, Latisha Nixon-Jones

Cleveland State Law Review

This Article proposes expanding the legal academy’s role in responding to disasters and emergencies, specifically through creating disaster clinics that take a community-based lawyering approach. The Article is one of the first to identify the need for community-based disaster legal clinical education that goes beyond the immediate response phase. It also proposes creating a disaster legal pipeline from the clinic through post-graduation employment. The Article furthers the literature’s discussion of the need for sustained disaster legal education. As the global pandemic caused by COVID-19 coronavirus continues to impact vulnerable populations and the frequency of natural disasters continues to increase, this …

Protocol For Developing A Personalised Prediction Model For Viral Suppression Among Under-Represented Populations In The Context Of The Covid-19 Pandemic, Jiajia Zhang Ph.D., Xueying Yang Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Bankole Olatosi Ph.D.

Faculty Publications

Introduction Sustained viral suppression, an indicator of long-term treatment success and mortality reduction, is one of four strategic areas of the 'Ending the HIV Epidemic' federal campaign launched in 2019. Under-represented populations, like racial or ethnic minority populations, sexual and gender minority groups, and socioeconomically disadvantaged populations, are disproportionately affected by HIV and experience a more striking virological failure. The COVID-19 pandemic might magnify the risk of incomplete viral suppression among under-represented people living with HIV (PLWH) due to interruptions in healthcare access and other worsened socioeconomic and environmental conditions. However, biomedical research rarely includes under-represented populations, resulting in biased …

Women And Children’S Victims Of Violence Case Management During Covid-19 Pandemic, Eti Sumiati, Elvy M. Manurung Dr., Indraswari - Ph. D

The Qualitative Report

Many studies have been conducted to prove the threat of violence against children and women during COVID-19. Unlike other studies, this study focuses more on government services in receiving complaints from victims of violence experienced by women and children during the COVID-19 pandemic. Using case studies as a qualitative method, documentary studies and in-depth interviews have been conducted on 13 informants from various parties in Bandung Regency, West Java, Indonesia. The results showed that the use of digital technology during the pandemic sometimes hampered the follow-up process for complaints of violence by victims due to a lack of equipment and …

Clinically Stable Covid-19 Patients Presenting To Acute Unscheduled Episodic Care Venues Have Increased Risk Of Hospitalization: Secondary Analysis Of A Randomized Control Trial, Joseph Bledsoe, Scott C Woller, Maria Brooks, Frank C Sciurba, Jerry A Krishnan, Deborah Martin, Peter Hou, Janet Y Lin, Andrei Kindzelski, Eileen Handberg, Bridget-Anne Kirwan, Elaine Zaharris, Lauren Castro, Nancy L Shapiro, Carl J Pepine, Sarah Majercik, Zhuxuan Fu, Yongqi Zhong, Vidya Venugopal, Yu-Hsuan Lai, Paul M Ridker, Jean M Connors

Faculty, Staff and Student Publications

BACKGROUND: Assessment for risks associated with acute stable COVID-19 is important to optimize clinical trial enrollment and target patients for scarce therapeutics. To assess whether healthcare system engagement location is an independent predictor of outcomes we performed a secondary analysis of the ACTIV-4B Outpatient Thrombosis Prevention trial.

METHODS: A secondary analysis of the ACTIV-4B trial that was conducted at 52 US sites between September 2020 and August 2021. Participants were enrolled through acute unscheduled episodic care (AUEC) enrollment location (emergency department, or urgent care clinic visit) compared to minimal contact (MC) enrollment (electronic contact from test center lists of positive …

Oral Changes In Hospitalized Covid-19 Patients: A Cross-Sectional Multicentric Study, Asmaa Ras, Radwa R. Hussein, Dalia M. Ghalwash, Ayman A. El-Gawish

Dentistry

Background. Coronavirus disease 2019 (COVID-19) has rapidly spread over the globe, and several oral symptoms have been documented. However, it is unclear whether these lesions are the result of coronavirus infection or are secondary symptoms of the patient’s systemic illness. The aim of this study was to collect data from various hospitals on COVID-19 patients with oral involvement in order to highlight different oral changes that may be manifested in those patients. Methods. This observational cross-sectional multicenter study used an online questionnaire covering oral signs and symptoms that were believed to be related to COVID-19 patients who were …

Our Magnitude And Bond: An Ethics Of Care For Art Museum Education, Dana Carlisle Kletchka

Journal of Social Theory in Art Education

This work responds to contemporary concerns about the future of art museum education and public practice and art museums more broadly in the wake of a global pandemic that has, at present, killed more than a million people in the United States and sickened millions more. I respond to questions posed by the board of the Journal of Social Theory in Art Education in relation to the theme of Inclusion Invasion, expand upon the relations between art museums and communities posited by a post-critical, socially responsive museological framework, and explore the potential for a feminist philosophical Ethics of Care …

Development Of Recombinant Varicella-Zoster Virus Vaccines Expressing Sars-Cov-2 Antigens, Cody Wilson

Honors Theses

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) continues to cause infections and deaths around the globe. Since its emergence, scientists have worked diligently to discover and produce vaccines to battle the virus. While they successfully created and distributed vaccines, the vaccines are not without flaw. These vaccines do not grant long term immunity, require multiple booster shots, and have not prevented the emergence of viral variants. In this study, the SARS-CoV-2 receptor binding domain (RBD), which is a key part of the spike protein (S), and nucleocapsid (N) genetic sequences were inserted into the live varicella …

The Essence Of K-12 Teaching In A Catholic Archdiocese In Kentucky During The Covid-19 Pandemic, Danielle Atzinger Wiegandt

Graduate Theses, Dissertations, and Capstones

Even before the COVID-19 pandemic research showed that teacher attrition among new teachers (less than five years) was a problem for schools throughout the country and Catholic Schools were facing an even higher rate (Ingersoll, 2003). Research also shows that there are often cultural and structural components of Catholic schools that influence teachers to stay (Youngs, 2013; Convey, 2012, 2014). The COVID-19 pandemic forced the education system to pivot and teachers are expected to continue to have high standards for education while making these shifts.

In the early period of COVID-19 pandemic research was already suggesting attrition rates were rising …

Academic Self-Efficacy In College Students During The Covid-19 Pandemic, Veronica Lane

Individual, Family, and Community Education ETDs

The purpose of this study was to explore academic self-efficacy and utility value for college coursework for college undergraduate students during the COVID-19 pandemic. In addition, the present study employed qualitative analysis to explore challenges students faced and what strategies they are using to promote their sense of well-being during the pandemic. One hundred eighty-seven undergraduates enrolled in educational psychology courses completed an online survey during the spring 2022 and summer 2022 semesters. The online survey consisted of a demographic questionnaire, two self-efficacy scales, and a utility value scale. In general, students had high levels of self-efficacy for graduating from …

Vaccine Uptake In The Era Of Covid-19: Associations Between Willingness To Receive The Influenza And Covid-19 Vaccines, Mutaz Alkalbani, Ritsa Frousios, Matilda Francis, Yousef Beidas, Jennifer Ryal, Brynn Sheehan

Virginia Journal of Public Health

Background/purpose. Despite efforts to increase flu vaccine uptake, the rate of vaccination remains below target. Additionally, many Virginians remain unvaccinated or have not maintained a booster schedule in line with recommendations. The current study investigated willingness to receive the flu and COVID-19 vaccines during the COVID-19 pandemic, associations between the likelihood of receiving the two vaccines, and differences in uptake by racial group and insurance status. Methods. Participants were adult patients seen for appointments at an ambulatory clinic in Southeast, VA. Participants completed a questionnaire assessing vaccination history and future vaccination intentions. Results. Results revealed significant associations between having received …

Bukola Adebayo, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Bukola Adebayo is an investigative journalist with over a decade of experience reporting health, science, politics, and education in Africa. She is now the West Africa correspondent for the Thomson Reuters Foundation (Nov. 2022 to now) covering human rights and issues around abuse and exploitation of everyday people in the big economy, environment, and tech space. During COVID, Bukola was the senior producer at the CNN Digital Bureau in Nigeria (Jan 2018- Aug 2021), where she covered many topics, including, human rights, women’s rights, social injustice, political uprisings, and the environment.

In this interview, Adebayo recalled her experience of covering …