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The Impact Of Fiscal Science And Technology Expenditure On Digital Economy: A New Path To Economic Recovery In The Post-Pandemic Era, Yang Xu, Xiaodong Yang, Qiying Ran Mar 2024

The Impact Of Fiscal Science And Technology Expenditure On Digital Economy: A New Path To Economic Recovery In The Post-Pandemic Era, Yang Xu, Xiaodong Yang, Qiying Ran

Bulletin of Monetary Economics and Banking

In this study, a multi-dimensional digital economy evaluation index system is constructed to explore the impact of fiscal Science and Technology (S&T) expenditure on digital economy development in China. We reveal the following findings. First, we note that the China’s digital economy level as a whole is rising each year, which is less affected by the COVID-19 pandemic. Second, we document that S&T expenditures positively stimulate digital economy development. Finally, we find that the promotion effect of S&T expenditure on the digital economy is statistically significant, and this promotion effect decreases from the southwest to the northeast due to the …


Will Green Finance Become A New Driving Force For Environmental Governance In The Post-Covid-19 Era: Evidence From China, Siyu Ren, Mingyue Du Mar 2024

Will Green Finance Become A New Driving Force For Environmental Governance In The Post-Covid-19 Era: Evidence From China, Siyu Ren, Mingyue Du

Bulletin of Monetary Economics and Banking

Green finance stimulus plan has become an important tool for environmental governance in the post-COVID-19 era. This paper investigates the emission reduction effect and impact mechanism of green finance (GF). The empirical results indicate that GF reduces environmental pollution. This reduction effect is attributed to a promotion in green innovation and industrial upgrading. The emission reduction effect of GF reflects the threshold characteristics. Specifically, stricter environmental regulation increases the inhibitory effect of GF on pollution


The Impact Of Covid-19 Pandemic On Carbon Emissions: Empirical Evidence From China, Yanwei Lyu, You Wu, Wenqiang Wang, Jinning Zhang Mar 2024

The Impact Of Covid-19 Pandemic On Carbon Emissions: Empirical Evidence From China, Yanwei Lyu, You Wu, Wenqiang Wang, Jinning Zhang

Bulletin of Monetary Economics and Banking

In this study, we investigate the short-term impact of the COVID-19 pandemic on China’s carbon emissions. We use data for a panel of 30 Chinese provinces over the period January 2020 to December 2020. The results indicate that carbon emissions in China decreased considerably during the COVID-19 outbreak. This finding remains robust when we use different proxies for core variables. The pandemic had a more pronounced impact on carbon emissionsin regions with a surplus of carbon emission allowances, and the negative effects of the pandemic on carbon emissions were greater in the first half of 2020 compared to the second …


Coping Strategies For Nurses’ Distress In Dealing With The Covid-19 Pandemic: A Scoping Review, Ika Nopa, L Meily Kurniawidjaja, Dadan Erwandi Mar 2024

Coping Strategies For Nurses’ Distress In Dealing With The Covid-19 Pandemic: A Scoping Review, Ika Nopa, L Meily Kurniawidjaja, Dadan Erwandi

Jurnal Keperawatan Indonesia

It is a well-known fact that the COVID-19 pandemic exacerbated the work stressors of nurses, which were already a problem previously, causing great distress. Hence, the need for effective coping strategies has been realized to prevent such distress, especially if a pandemic recurs. Determining how the types of coping strategies used by nurses impact their distress level in COVID-19 Pandemic. This review was conducted using the PRISMA Statement Recommendations Checklist and PRISMA—Extension for Scoping Reviews (PRISMA-SCR). The databases used were Willey Library, Science Direct, SCOPUS, and Springer Link for the literature search. Nurse and (“coping type” or “brief cope”) and …


Covid-19 Vaccine Effectiveness Among People Living With And Without Hiv In South Carolina, Usa: Protocol Of A Population-Based Cohort Study, Xueying Yang, Jiajia Zhang Ph.D., Bankole Olatosi, Sharon Weissman, Xiaoming Li Ph.D. Mar 2024

Covid-19 Vaccine Effectiveness Among People Living With And Without Hiv In South Carolina, Usa: Protocol Of A Population-Based Cohort Study, Xueying Yang, Jiajia Zhang Ph.D., Bankole Olatosi, Sharon Weissman, Xiaoming Li Ph.D.

Faculty Publications

Introduction Despite the effectiveness of COVID-19 vaccines in preventing severe COVID-19 outcomes, a small percentage of fully vaccinated persons will develop symptomatic or asymptomatic infections with SARSCoV-2, which is referred to as ‘breakthrough COVID-19’. People living with HIV (PLWH) appear to have an elevated risk of severe COVID-19 outcomes, yet the effectiveness of the COVID-19 vaccine in this population remains unclear due to the limited research efforts in this population in the real world. This study aims to characterise and compare the breakthrough COVID-19 (eg, prevalence and disease severity) between PLWH and non-PLWH and then examine whether HIV markers play …


Pre-Covid-19 Hospital Quality And Hospital Response To Covid-19: Examining Associations Between Risk-Adjusted Mortality For Patients Hospitalised With Covid-19 And Pre-Covid-19 Hospital Quality, Doris Peter, Shu-Xia Li, Yongfei Wang, Jing Zhang, Jacqueline Grady, Kerry Mcdowell, Erica Norton, Zhenqiu Lin, Susannah Bernheim, Arjun K Venkatesh, Lee A Fleisher, Michelle Schreiber, Lisa G Suter, Elizabeth W Triche Mar 2024

Pre-Covid-19 Hospital Quality And Hospital Response To Covid-19: Examining Associations Between Risk-Adjusted Mortality For Patients Hospitalised With Covid-19 And Pre-Covid-19 Hospital Quality, Doris Peter, Shu-Xia Li, Yongfei Wang, Jing Zhang, Jacqueline Grady, Kerry Mcdowell, Erica Norton, Zhenqiu Lin, Susannah Bernheim, Arjun K Venkatesh, Lee A Fleisher, Michelle Schreiber, Lisa G Suter, Elizabeth W Triche

Faculty, Staff and Student Publications

OBJECTIVES: The extent to which care quality influenced outcomes for patients hospitalised with COVID-19 is unknown. Our objective was to determine if prepandemic hospital quality is associated with mortality among Medicare patients hospitalised with COVID-19.

DESIGN: This is a retrospective observational study. We calculated hospital-level risk-standardised in-hospital and 30-day mortality rates (risk-standardised mortality rates, RSMRs) for patients hospitalised with COVID-19, and correlation coefficients between RSMRs and pre-COVID-19 hospital quality, overall and stratified by hospital characteristics.

SETTING: Short-term acute care hospitals and critical access hospitals in the USA.

PARTICIPANTS: Hospitalised Medicare beneficiaries (Fee-For-Service and Medicare Advantage) age 65 and older hospitalised …


Usage Of Arsenicum Album 30c As A Prophylactic Medicine In Healthcare Workers Of A Covid Health Centre – A Report, Rekha Thomas, Thankaraj Balakrishnan, Anu Rajesh, George Mathew, Saurabh Kumar Jain, Radhika Agarwal, Anu Kapoor Mar 2024

Usage Of Arsenicum Album 30c As A Prophylactic Medicine In Healthcare Workers Of A Covid Health Centre – A Report, Rekha Thomas, Thankaraj Balakrishnan, Anu Rajesh, George Mathew, Saurabh Kumar Jain, Radhika Agarwal, Anu Kapoor

Indian Journal of Research in Homoeopathy

The homoeopathic medicine Arsenicum album 30C was recommended as prophylaxis by the Central Council for Research in Homoeopathy, along with general precautions during COVID-19 pandemic. A retrospective cohort study was conducted in Delhi, India, during May–August 2020 to evaluate the effectiveness of Arsenicum album 30C as prophylaxis for COVID-19 in a high-risk group of healthcare workers (HCWs). HCWs (n = 100) were categorised into two groups based on the number of days Arsenicum album 30C was administered during their duty: 7 days (N1 = 38) or 14 days (N2 = 62). Participants underwent COVID-19 testing (rapid antigen test/reverse transcriptase-polymerase chain …


Research Highlights, Bhavna Makhija, Khan Sheeba Saleem Mar 2024

Research Highlights, Bhavna Makhija, Khan Sheeba Saleem

Indian Journal of Research in Homoeopathy

Research Highlights


Hypermetabolic Lymphadenopathy Following The Administration Of Covid-19 Vaccine And Immunotherapy In A Lung Cancer Patient: A Case Report, Shreya Tripathy, Nathaniel Alvarez, Shubham Jaiswal, Ryan Williams, Munaf Al-Khadimi, Sarah Hackman, William Phillips, Supreet Kaur, Sherri Cervantez, William Kelly, Josephine Taverna Mar 2024

Hypermetabolic Lymphadenopathy Following The Administration Of Covid-19 Vaccine And Immunotherapy In A Lung Cancer Patient: A Case Report, Shreya Tripathy, Nathaniel Alvarez, Shubham Jaiswal, Ryan Williams, Munaf Al-Khadimi, Sarah Hackman, William Phillips, Supreet Kaur, Sherri Cervantez, William Kelly, Josephine Taverna

Research Symposium

Background: Given the current climate of the pandemic, lung cancer patients are especially vulnerable to complications from severe acute respiratory syndrome coronavirus 2 infection. As a high-risk population group, these patients are strongly advised to receive coronavirus disease 2019 vaccination in accordance with Center for Disease Control and Prevention guidelines to minimize morbidity and mortality. In recent years, immunotherapy has taken a preeminent role in the treatment of non-small cell lung cancer with dramatic improvement in overall survival. Reactive lymphadenopathy following the administration of a coronavirus disease 2019 vaccination can confound the radiographic interpretation of positron emission tomography-computed tomography or …


Consensus Pharmacophore Strategy For Identifying Novel Sars-Cov-2 Mpro Inhibitors From Large Chemical Libraries, Angel J Ruiz-Moreno, Raziel Cedillo-González, Luis Cordova-Bahena, Zhiqiang An, José L Medina-Franco, Marco A Velasco-Velázquez Mar 2024

Consensus Pharmacophore Strategy For Identifying Novel Sars-Cov-2 Mpro Inhibitors From Large Chemical Libraries, Angel J Ruiz-Moreno, Raziel Cedillo-González, Luis Cordova-Bahena, Zhiqiang An, José L Medina-Franco, Marco A Velasco-Velázquez

The Brown Foundation: Institute of Molecular Medicine

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main Protease (Mpro) is an enzyme that cleaves viral polyproteins translated from the viral genome and is critical for viral replication. Mpro is a target for anti-SARS-CoV-2 drug development, and multiple Mpro crystals complexed with competitive inhibitors have been reported. In this study, we aimed to develop an Mpro consensus pharmacophore as a tool to expand the search for inhibitors. We generated a consensus model by aligning and summarizing pharmacophoric points from 152 bioactive conformers of SARS-CoV-2 Mpro inhibitors. Validation against a library of conformers from a subset of ligands showed that …


The Disordered N-Terminal Tail Of Sars-Cov-2 Nucleocapsid Protein Forms A Dynamic Complex With Rna, Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton, Andrea Soranno Mar 2024

The Disordered N-Terminal Tail Of Sars-Cov-2 Nucleocapsid Protein Forms A Dynamic Complex With Rna, Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton, Andrea Soranno

2020-Current year OA Pubs

The SARS-CoV-2 Nucleocapsid (N) protein is responsible for condensation of the viral genome. Characterizing the mechanisms controlling nucleic acid binding is a key step in understanding how condensation is realized. Here, we focus on the role of the RNA binding domain (RBD) and its flanking disordered N-terminal domain (NTD) tail, using single-molecule Förster Resonance Energy Transfer and coarse-grained simulations. We quantified contact site size and binding affinity for nucleic acids and concomitant conformational changes occurring in the disordered region. We found that the disordered NTD increases the affinity of the RBD for RNA by about 50-fold. Binding of both nonspecific …


Working Remotely And Corporate Culture Wars In The Post-Pandemic Era, David M. Savino, Danielle C. Foster Mar 2024

Working Remotely And Corporate Culture Wars In The Post-Pandemic Era, David M. Savino, Danielle C. Foster

Journal of the North American Management Society

Organizational culture is a sacred element of any organization. It is the lifeblood and the guiding force that makes each organization unique in its ability to navigate day-to-day and longer-term perspectives of corporate operations. Strong cultures help identify direction and philosophy and provide confidence in how to proceed to pursue innovative ideas and solve problems. Since 2020, the core value and the strength of many organizational cultures have been tested as a result of the increased reliance on working remotely and the adoption of a hybrid model of business operations not previously utilized to a great degree. While many survived …


Reliability And Validity Of The Patient Health Questionnaire-4 Scale And Its Subscales Of Depression And Anxiety Among Us Adults Based On Nativity, David Adzrago, Timothy J Walker, Faustine Williams Mar 2024

Reliability And Validity Of The Patient Health Questionnaire-4 Scale And Its Subscales Of Depression And Anxiety Among Us Adults Based On Nativity, David Adzrago, Timothy J Walker, Faustine Williams

Faculty, Staff and Student Publications

BACKGROUND: The burdens of anxiety and depression symptoms have significantly increased in the general US population, especially during this COVID-19 epidemiological crisis. The first step in an effective treatment for anxiety and depression disorders is screening. The Patient Health Questionnaire-4 (PHQ-4, a 4-item measure of anxiety/depression) and its subscales (PHQ-2 [a 2-item measure of depression] and Generalized Anxiety Disorder [GAD-2, a 2-item measure of anxiety]) are brief but effective mass screening instruments for anxiety and depression symptoms in general populations. However, little to no study examined the psychometric properties (i.e., reliability and validity) of the PHQ-4 and its subscales (PHQ-2 …


Effect Of Neutralizing Monoclonal Antibody Treatment On Early Trajectories Of Virologic And Immunologic Biomarkers In Patients Hospitalized With Covid-19, Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko, Activ-3/Tico Study Group Mar 2024

Effect Of Neutralizing Monoclonal Antibody Treatment On Early Trajectories Of Virologic And Immunologic Biomarkers In Patients Hospitalized With Covid-19, Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko, Activ-3/Tico Study Group

Faculty, Staff and Student Publications

BACKGROUND: Neutralizing monoclonal antibodies (nmAbs) failed to show clear benefit for hospitalized patients with coronavirus disease 2019 (COVID-19). Dynamics of virologic and immunologic biomarkers remain poorly understood.

METHODS: Participants enrolled in the Therapeutics for Inpatients with COVID-19 trials were randomized to nmAb versus placebo. Longitudinal differences between treatment and placebo groups in levels of plasma nucleocapsid antigen (N-Ag), anti-nucleocapsid antibody, C-reactive protein, interleukin-6, and D-dimer at enrollment, day 1, 3, and 5 were estimated using linear mixed models. A 7-point pulmonary ordinal scale assessed at day 5 was compared using proportional odds models.

RESULTS: Analysis included 2149 participants enrolled between …


Changes In Human Resources Function In Higher Education Institutions During A Pandemic, Naterena Anevia Parham-Cofield Mar 2024

Changes In Human Resources Function In Higher Education Institutions During A Pandemic, Naterena Anevia Parham-Cofield

Walden Dissertations and Doctoral Studies

Pandemics have reshaped societies and paved ways for advances in sciences, political systems, technology, medicine, and the economy. However, researchers have not explored how human resources (HR) function changes due to a pandemic in higher education institutions (HEIs) and how managing it contributes to employee performance and employee well-being. The purpose of this qualitative descriptive multiple case study was to explore how HR function changed due to the COVID-19 pandemic in different types of HEIs and how managing it contributed to employee performance and employee well-being. The study was grounded in Kotter’s eight-step change management model. Data were collected through …


Effect Of Neutralizing Monoclonal Antibody Treatment On Early Trajectories Of Virologic And Immunologic Biomarkers In Patients Hospitalized With Covid-19, Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko Mar 2024

Effect Of Neutralizing Monoclonal Antibody Treatment On Early Trajectories Of Virologic And Immunologic Biomarkers In Patients Hospitalized With Covid-19, Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko

Faculty, Staff and Student Publications

BACKGROUND: Neutralizing monoclonal antibodies (nmAbs) failed to show clear benefit for hospitalized patients with coronavirus disease 2019 (COVID-19). Dynamics of virologic and immunologic biomarkers remain poorly understood.

METHODS: Participants enrolled in the Therapeutics for Inpatients with COVID-19 trials were randomized to nmAb versus placebo. Longitudinal differences between treatment and placebo groups in levels of plasma nucleocapsid antigen (N-Ag), anti-nucleocapsid antibody, C-reactive protein, interleukin-6, and D-dimer at enrollment, day 1, 3, and 5 were estimated using linear mixed models. A 7-point pulmonary ordinal scale assessed at day 5 was compared using proportional odds models.

RESULTS: Analysis included 2149 participants enrolled between …


Outpatient Covid-19 Convalescent Plasma Recipient Antibody Thresholds Correlated To Reduced Hospitalizations Within A Randomized Trial, Han-Sol Park, Anna Yin, Caelan Barranta, John S Lee, Christopher A Caputo, Jaiprasath Sachithanandham, Maggie Li, Steve Yoon, Ioannis Sitaras, Anne Jedlicka, Yolanda Eby, Malathi Ram, Reinaldo E Fernandez, Owen R Baker, Aarthi G Shenoy, Giselle S Mosnaim, Yuriko Fukuta, Bela Patel, Sonya L Heath, Adam C Levine, Barry R Meisenberg, Emily S Spivak, Shweta Anjan, Moises A Huaman, Janis E Blair, Judith S Currier, James H Paxton, Jonathan M Gerber, Joann R Petrini, Patrick B Broderick, William Rausch, Marie Elena Cordisco, Jean Hammel, Benjamin Greenblatt, Valerie C Cluzet, Daniel Cruser, Kevin Oei, Matthew Abinante, Laura L Hammitt, Catherine G Sutcliffe, Donald N Forthal, Martin S Zand, Edward R Cachay, Jay S Raval, Seble G Kassaye, Christi E Marshall, Anusha Yarava, Karen Lane, Nichol A Mcbee, Amy L Gawad, Nicky Karlen, Atika Singh, Daniel E Ford, Douglas A Jabs, Lawrence J Appel, David M Shade, Bryan Lau, Stephan Ehrhardt, Sheriza N Baksh, Janna R Shapiro, Jiangda Ou, Yu Bin Na, Maria D Knoll, Elysse Ornelas-Gatdula, Netzahualcoyotl Arroyo-Curras, Thomas J Gniadek, Patrizio Caturegli, Jinke Wu, Nelson Ndahiro, Michael J Betenbaugh, Alyssa Ziman, Daniel F Hanley, Arturo Casadevall, Shmuel Shoham, Evan M Bloch, Kelly A Gebo, Aaron Ar Tobian, Oliver Laeyendecker, Andrew Pekosz, Sabra L Klein, David J Sullivan Mar 2024

Outpatient Covid-19 Convalescent Plasma Recipient Antibody Thresholds Correlated To Reduced Hospitalizations Within A Randomized Trial, Han-Sol Park, Anna Yin, Caelan Barranta, John S Lee, Christopher A Caputo, Jaiprasath Sachithanandham, Maggie Li, Steve Yoon, Ioannis Sitaras, Anne Jedlicka, Yolanda Eby, Malathi Ram, Reinaldo E Fernandez, Owen R Baker, Aarthi G Shenoy, Giselle S Mosnaim, Yuriko Fukuta, Bela Patel, Sonya L Heath, Adam C Levine, Barry R Meisenberg, Emily S Spivak, Shweta Anjan, Moises A Huaman, Janis E Blair, Judith S Currier, James H Paxton, Jonathan M Gerber, Joann R Petrini, Patrick B Broderick, William Rausch, Marie Elena Cordisco, Jean Hammel, Benjamin Greenblatt, Valerie C Cluzet, Daniel Cruser, Kevin Oei, Matthew Abinante, Laura L Hammitt, Catherine G Sutcliffe, Donald N Forthal, Martin S Zand, Edward R Cachay, Jay S Raval, Seble G Kassaye, Christi E Marshall, Anusha Yarava, Karen Lane, Nichol A Mcbee, Amy L Gawad, Nicky Karlen, Atika Singh, Daniel E Ford, Douglas A Jabs, Lawrence J Appel, David M Shade, Bryan Lau, Stephan Ehrhardt, Sheriza N Baksh, Janna R Shapiro, Jiangda Ou, Yu Bin Na, Maria D Knoll, Elysse Ornelas-Gatdula, Netzahualcoyotl Arroyo-Curras, Thomas J Gniadek, Patrizio Caturegli, Jinke Wu, Nelson Ndahiro, Michael J Betenbaugh, Alyssa Ziman, Daniel F Hanley, Arturo Casadevall, Shmuel Shoham, Evan M Bloch, Kelly A Gebo, Aaron Ar Tobian, Oliver Laeyendecker, Andrew Pekosz, Sabra L Klein, David J Sullivan

Faculty, Staff and Students Publications

BACKGROUND

COVID-19 convalescent plasma (CCP) virus-specific antibody levels that translate into recipient posttransfusion antibody levels sufficient to prevent disease progression are not defined.

METHODS

This secondary analysis correlated donor and recipient antibody levels to hospitalization risk among unvaccinated, seronegative CCP recipients within the outpatient, double-blind, randomized clinical trial that compared CCP to control plasma. The majority of COVID-19 CCP arm hospitalizations (15/17, 88%) occurred in this unvaccinated, seronegative subgroup. A functional cutoff to delineate recipient high versus low posttransfusion antibody levels was established by 2 methods: (i) analyzing virus neutralization–equivalent anti–Spike receptor-binding domain immunoglobulin G (anti-S-RBD IgG) responses in donors …


Calpain-2 Mediates Sars-Cov-2 Entry Via Regulating Ace2 Levels, Qiru Zeng, Avan Antia, Luis Alberto Casorla-Perez, Maritza Puray-Chavez, Sebla B Kutluay, Matthew A Ciorba, Siyuan Ding Mar 2024

Calpain-2 Mediates Sars-Cov-2 Entry Via Regulating Ace2 Levels, Qiru Zeng, Avan Antia, Luis Alberto Casorla-Perez, Maritza Puray-Chavez, Sebla B Kutluay, Matthew A Ciorba, Siyuan Ding

2020-Current year OA Pubs

UNLABELLED: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, much effort has been dedicated to identifying effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of calpain inhibitors show excellent antiviral activities against SARS-CoV-2 by targeting the viral main protease (M

IMPORTANCE: Many efforts in small-molecule screens have been made to counter SARS-CoV-2 infection by targeting the viral main protease, the major element that processes viral proteins after translation. Here, we discovered that calpain inhibitors further block SARS-CoV-2 infection in a main protease-independent manner. We identified the host cysteine protease calpain-2 as an important positive …


Waiving Snap Interviews During The Covid-19 Pandemic Increased Snap Caseloads, Colleen Heflin, William Fannin, Leonard M. Lopoo, Siobhan O'Keefe Mar 2024

Waiving Snap Interviews During The Covid-19 Pandemic Increased Snap Caseloads, Colleen Heflin, William Fannin, Leonard M. Lopoo, Siobhan O'Keefe

Population Health Research Brief Series

Food insecurity in the United States reached historically high rates during the COVID-19 pandemic, thus substantially increasing demand for the Supplemental Nutrition Assistance Program (SNAP). To facilitate access to SNAP during the pandemic, the federal government granted state SNAP offices the option to waive the interview requirement – an administrative burden associated with the SNAP certification process. This brief summarizes findings from a recent study that used data from SNAP offices across 10 states to examine the impact of SNAP interview waivers on SNAP caseloads from January 5th to April 30th of 2021. Findings reveal that counties that implemented the …


Covid-19 And Non-Traditional Security, Arup Maity, Rajani Kant Pandey Mar 2024

Covid-19 And Non-Traditional Security, Arup Maity, Rajani Kant Pandey

The World Research of Political Science Journal

Around 100 years ago, John Maynard Keynes, the most distinguished economist of modern times, published a book A Treatise on Probability (1921), and in this book, as a scholar, he argued for changes instead of the ‘traditional theory,’ and significantly the time was the middle of the World War. Now the world has reached 2021 with the depletive COVID-19 and is battling against it. Covid is a virus that we cannot see with just an open eye, but its impact has caused around 40 million human deaths, and we can see our world as pandemonium with only an open eye. …


A Global Health Crisis And Its Effects On Teaching Online At A Midwestern Institution, Kari Mcmullen Mar 2024

A Global Health Crisis And Its Effects On Teaching Online At A Midwestern Institution, Kari Mcmullen

Theses and Dissertations

This study examined faculty experiences and perceptions regarding online education during the COVID-19 global health crisis. An online survey was assessed for content validity using a team of faculty experts in online teaching and learning. It was administered to a convenience sample of faculty at a Midwestern university. Of the 963 faculty who were surveyed, 98 returned the survey, a return rate of about 10%. The analysis of faculty experiences indicated that faculty adopted new pedagogical practices into their curriculum, specifically problem-based (18.37%) and self-paced learning (5.31%). Additionally, faculty adjusted assessments (42.86%), modified instruction (39.80%), and changed assignment due dates …


Exploring Barriers To Effective Covid-19 Risk Mitigation, Recovery, And Chronic Disease Self-Management: A Qualitative Multilevel Perspective, Gayenell S. Magwood Phd, Rn, Faha, Faan, Charles Ellis Jr, Chanita Hughes Halbert, Ebony Allen Toussaint, Jewel Scott, Lynne S. Nemeth Mar 2024

Exploring Barriers To Effective Covid-19 Risk Mitigation, Recovery, And Chronic Disease Self-Management: A Qualitative Multilevel Perspective, Gayenell S. Magwood Phd, Rn, Faha, Faan, Charles Ellis Jr, Chanita Hughes Halbert, Ebony Allen Toussaint, Jewel Scott, Lynne S. Nemeth

Publications

Introduction: Many research activities have focused on SARS-CoV-2 infection and subsequent COVID-19 respiratory illness during the pandemic. However, significant racial inequities emerged months after the COVID-19 pandemic began. The similarity between racial/ ethnic disparities in COVID-19 and those for other diseases raised awareness about the context for risk exposure and healthcare access. The purpose of this study is to examine social and structural determinants of health among COVID-19 survivors, carepartners, and the perspectives of healthcare stakeholders who experienced disruption during the early pandemic.
Material and methods: A purposive sample of interviews (n=9) and focus groups (n=10) were used to collect …


Fraud Brainstorming In An Era Of Remote Work: The Effects Of Alternative Video Conferencing Configurations And Audit Team Hierarchy, Ahmed Shuaib Mar 2024

Fraud Brainstorming In An Era Of Remote Work: The Effects Of Alternative Video Conferencing Configurations And Audit Team Hierarchy, Ahmed Shuaib

USF Tampa Graduate Theses and Dissertations

In 2020, the coronavirus pandemic prompted governments to respond by implementing social distancing regulations and travel bans. Although these actions helped mitigate the spread of the virus, they also created unique challenges for businesses and their employees. Firms transitioned quickly from face-to-face work settings to remote work arrangements using video conferencing technologies (VCT). These technologies enable video calls with or without instant messaging (chat) to facilitate information exchange. For audit firms, group tasks that were previously performed in face-to-face settings had to be performed using VCT. A commonly performed group task in auditing is fraud brainstorming, which auditing standards require …


Reports Of Covid-19 Vaccine Adverse Events In Predominantly Republican Vs Democratic States, David A Asch, Chongliang Luo, Yong Chen Mar 2024

Reports Of Covid-19 Vaccine Adverse Events In Predominantly Republican Vs Democratic States, David A Asch, Chongliang Luo, Yong Chen

2020-Current year OA Pubs

IMPORTANCE: Antivaccine sentiment is increasingly associated with conservative political positions. Republican-inclined states exhibit lower COVID-19 vaccination rates, but the association between political inclination and reported vaccine adverse events (AEs) is unexplored.

OBJECTIVE: To assess whether there is an association between state political inclination and the reporting rates of COVID-19 vaccine AEs.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used the AE reports after COVID-19 vaccination from the Vaccine Adverse Event Reporting System (VAERS) database from 2020 to 2022, with reports after influenza vaccines from 2019 to 2022 used as a reference. These reports were examined against state-level percentage of Republican …


Life Satisfaction Changes And Adaptation In The Covid-19 Pandemic: Evidence From Singapore, Terence C. Cheng, Seonghoon Kim, Kanghyock Koh Mar 2024

Life Satisfaction Changes And Adaptation In The Covid-19 Pandemic: Evidence From Singapore, Terence C. Cheng, Seonghoon Kim, Kanghyock Koh

Research Collection School Of Economics

We provide novel evidence on how COVID-19 affected overall life satisfaction using a monthly longitudinal survey of middle-aged and older Singaporeans. We study how the subjective well-being of individuals evolves over the course of 18 months including the outbreak of the pandemic, the implementation of the lockdown and the spike of cases due to the delta variant in a country where COVID-19 is controlled in a sustained manner. Using an event-study design framework, we find large declines in overall life satisfaction in the lead-up to and following the lockdown. Fifteen months after the outbreak of the pandemic, and 13 months …


What Hospitality And Tourism Higher Educators Learned From Covid-19: A Case Of Turkiye, Ayse Collins, Ayse S. Dulger, Muharrem Tuna, Muzaffer Uysal Mar 2024

What Hospitality And Tourism Higher Educators Learned From Covid-19: A Case Of Turkiye, Ayse Collins, Ayse S. Dulger, Muharrem Tuna, Muzaffer Uysal

Journal of Global Education and Research

Among all the sectors, the hospitality and tourism sector has been detrimentally affected by the impact of the COVID-19 pandemic. This research aimed to determine how changes have been experienced specifically in the Turkish tourism higher education and tourism sector. Twenty-seven academics from the hospitality and tourism education departments were interviewed. Most agreed that restrictions have limited student access to hands-on practical courses and internships, which are crucial to developing necessary competencies. Moreover, the results showed the curriculum does not always meet the needs of the hospitality industry for a trained and skilled workforce. The challenge is to decide what …


Investigating The Management Of Covid-19 Pandemic Risks In Primary Schools: A Case Of Public Primary Schools In Lindi Region, Southern Tanzania, Emmanuel Mutura, Winston Edward Massam, Mary Oluga, Jane Rarieya, Nyagwegwe Wango Mar 2024

Investigating The Management Of Covid-19 Pandemic Risks In Primary Schools: A Case Of Public Primary Schools In Lindi Region, Southern Tanzania, Emmanuel Mutura, Winston Edward Massam, Mary Oluga, Jane Rarieya, Nyagwegwe Wango

Institute for Educational Development, East Africa

The spread of COVID-19 in the year 2020 put various nations at risk, especially in social, economic, and educational aspects. School closure was employed as one of the response measures against the spread of this virus. However, the measure imposed high social and educational risks with consequences of a massive drop academically. This study investigated the management of the COVID-19 pandemic risks in primary schools in the Lindi region in Tanzania intending to suggest the essence of having a risk management plan for indeterminate outbreaks and other uncertainties to avoid the recurrence of the risks. The study adopted a qualitative …


A Socio-Ecological Approach To A Community-Based Health Promotion Intervention On The U.S.-Mexico Border: Insights And Lessons Learned During The Covid-19 Pandemic, Yok-Fong Paat, Elizabeth Camacho, Sarah L. Ruiz, Diego Garcia Tovar, Guillermina Gina Núñez-Mchiri, Maria O. Duarte-Gardea, Guadalupe Corral, Sandra Oviedo Ramirez, Christine Markham, Luis R. Torres-Hostos Mar 2024

A Socio-Ecological Approach To A Community-Based Health Promotion Intervention On The U.S.-Mexico Border: Insights And Lessons Learned During The Covid-19 Pandemic, Yok-Fong Paat, Elizabeth Camacho, Sarah L. Ruiz, Diego Garcia Tovar, Guillermina Gina Núñez-Mchiri, Maria O. Duarte-Gardea, Guadalupe Corral, Sandra Oviedo Ramirez, Christine Markham, Luis R. Torres-Hostos

School of Social Work Faculty Publications

The Healthy Families Healthy Kids Initiative (HFHKI) is a community-based initiative developed based on the socio-ecological model to address preventive health care needs in El Paso County, Texas, one of the most economically and health-challenged border communities in the United States. HFHKI’s three main goals are to increase access to experiential learning and health education, service delivery, and sustainable systems/linkages of care. These were accomplished through seven critical activities. We present the rationale, background, setting, and conceptual framework for the initiative, followed by the methods used to develop and assess the success of the activities and results of our project …


Navigating Covid-19 And Racial Trauma As A Black Student At Predominantly White Institutions, Samantha Francois, Joan Blakey, Rae Stevenson, Timothy Walker, Curtis Davis Mar 2024

Navigating Covid-19 And Racial Trauma As A Black Student At Predominantly White Institutions, Samantha Francois, Joan Blakey, Rae Stevenson, Timothy Walker, Curtis Davis

Psychology

Black students at predominantly White institutions (PWIs) contend with racial microaggressions that can lead to negative mental health and academic outcomes. The physical and mental health consequences of the novel coronavirus pandemic are well-known. What remains unknown is how targeted racial hate during a pandemic might have a compounded effect on Black essential workers. The current study examines how future essential workers in helping professions cope with dual crises as they navigate mostly White universities. Study participants were Black university students attending PWIs in the United States enrolled in social work, public health, or psychology programs during the 2020–2021 academic …


Measuring The Comparative Performance Of Usaf Behavioral Health Clinic Operations: Emphasis On Capacity, Daniel L. Straw Mar 2024

Measuring The Comparative Performance Of Usaf Behavioral Health Clinic Operations: Emphasis On Capacity, Daniel L. Straw

Theses and Dissertations

This research examines the operations of behavioral health clinics in Air Force Continental United States facilities, with a focus on operational efficiency and capacity through Data Envelopment Analysis. Most facilities operate near capacity, demonstrating efficient resource usage, but concerns arise with the potential of increased demand. Days-to-care and leakage are identified as major sources of inefficiency, suggesting that addressing these issues can enhance operations and reduce costs. The study also explores the impact of COVID-19 on care delivery.