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Synthesis And Molecular Docking Study Of Novel Covid-19 Inhibitors, Zuhal Gerçek, Deni̇z Ceyhan, Erol Erçağ

Turkish Journal of Chemistry

In 2020, the world tried to combat the corona virus (COVID-19) pandemic. A proven treatment method specific to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is still not found. In this study, seven new antiviral compounds were designed for COVID-19 treatment. The ability of these compounds to inhibit COVID-19's RNA processing was calculated by the molecular docking study. It has been observed that the compounds can have high binding affinities especially against NSP12 (between -9.06 and -8.00 kcal/mol). The molecular dynamics simulation of NSP12-ZG 7 complex proved the stability of interaction. The synthesis of two most active molecules was performed by …

Examining The Experiences Of Nordoff-Robbins Level One Trainees Amid The Covid-19 Pandemic, Gisela X. Berrones Cortez

Theses & Dissertations

This phenomenological study aimed to analyze the experiences of Nordoff-Robbins level one trainees in the United States amid significant platform shifts as a result of the global COVID-19 pandemic. Data collection consisted of semi-structured virtual interviews that primarily focused on the experiences of trainees as students/supervisees and as providers of music-centered music therapy services. Emergent themes included (1) Shared Musical Space When Not Physically Together, (2) The Impact of Virtual Platforms on the Experience of Musical Aesthetic, (3) The Nordoff-Robbins Trainee’s Relationship with the Musical Self, and (4) Growth Resulting from Unforeseen Change. Findings reveal that interpersonal and intrapersonal dynamics, …

Campus Recreation And Fitness Center Utilization During The Covid-19 Pandemic, Keagan Kiely, William Mase, Bridget F. Melton, Haresh Rochani Dr.

Health Sciences & Kinesiology: Faculty Publications

Background

The impact of the COVID-19 pandemic has far reaching effects for college students' health and physical activity behaviors. This analysis focuses on university student fitness center usage pre and during the COVID-19 pandemic. Researchers hypothesized a reduction in fitness center utilization when comparing Fall 2019 to Fall 2020 utilization rates.

Methods

Patterns of the recreation center and fitness center utilization during the COVID-19 pandemic are compared to pre-pandemic patterns of a matched time period in the previous academic year in an observational study. Overall utilization was evaluated using secondary data from the university’s recreation center data system. Six weeks …

Influence Of Political Affiliation On Perceived Media Bias And Trustworthiness In The Covid-19 Pandemic, Tabitha Lamberth

College of Graduate Studies: Theses & Dissertations

Partisanship and news source attribution may influence perceived media bias and trust in COVID-19 information. This study aimed to explore how the similarity liking effect relates to political identity and perceived credibility. Our main hypothesis was that individuals would find news sources that shared their political affiliation as more trustworthy than other news sources. To test our hypothesis, 216 undergraduate students participated in a study that measured participants’ trustworthiness of a news article with randomized source attribution from a liberal, conservative, and neutral source. A 2X3 ANOVA tested the relationship between our participants’ political affiliation, measured by the 12-item Social …

Teaching With Passion And Compassion In Challenging Times: A Narrative Inquiry Into Elementary Teachers' Experiences In Georgia, Erin Scroggs

College of Graduate Studies: Theses & Dissertations

This study explores how teachers maintain their passion and compassion for teaching in spite of the impact of work-related challenges and subsequent obstacles upon their personal and professional lives. While much research has been conducted into teacher stress, very little has been done to connect the effects of stress on teachers’ health and passions for teaching. Abby, Nick, Passion, and Anna, four elementary school teachers from different areas, counties, schools, and school districts in the State of Georgia, participated in the study. Theoretically, I draw upon an array of works such as teaching towards freedom (Ayers, 2004, 2010, 2016), teachers …

The Association Of Demographic Characteristics And Social Vulnerability With Covid-19 Outcomes, Gloria D. Boone

College of Graduate Studies: Theses & Dissertations

The Association of Demographic Characteristics and Social Vulnerability With COVID-19 Outcomes

by

Gloria Boone

(Under the Direction of Gulzar Shah)

ABSTRACT

This research explored 102 Illinois counties' COVID-19 data to determine whether demographic characteristics and social vulnerability are associated with increased vulnerability to COVID-19 infections and deaths. COVID-19 is disproportionately impacting vulnerable groups and has been deadlier for African American and Hispanic people. The findings of this research will contribute to the knowledge base regarding social vulnerability and assist public health officials in targeting resources and designing interventions. This study used a retrospective cross-sectional design to assess demographic characteristics of …

Strategic Implications Of Covid-19: Considerations For Georgia’S Rural Health Providers, Bettye A. Apenteng, Linda Kimsey, Charles Owens, Samuel T. Opoku, Angela Peden, William Mase

Health Policy & Community Health: Faculty Publications

Whether rural hospitals and providers have seen a surge in COVID-19 cases or a reduction in patients seeking care since the pandemic began, their financial condition has been negatively impacted. Many providers have now received some emergency funding through the Coronavirus Aid, Relief, and Economic Security Act and the Payroll Protection Program but these are likely only short-term fixes. For many, the crisis has exacerbated already existing problems. Notable among these problems are volume declines, supply chain disruptions, and workforce concerns. While these problems require immediate action, two longer-term systemic changes to rural healthcare delivery are needed to address them. …

Rapid Transition Of A Technical Course From Face-To-Face To Online, Swapna Gottipatti, Venky Shankaraman

Research Collection School Of Computing and Information Systems

Just like most universities around the world, the senior management at Singapore Management University decided to move all courses to a virtual, online, synchronous mode, giving instructors a very short notice period—one week—to make this transition. In this paper, we describe the challenges, practical solutions adopted, and the lessons learnt in rapidly transitioning a face-to-face Master’s degree course in Text Analytics and Applications into a virtual, online, course format that could deliver a quality learning experience.

Lessons From Our Living Rooms: Illuminating Lockdowns With Technology Domestication Insights, Sun Sun Lim, Yang Wang

Research Collection College of Integrative Studies

With at least half of humanity under lockdown to arrest the spread of COVID-19 (Sandford, 2020), adults have been working from home and children engaging in home schooling for months on end. Competing for scarce resources such as digital devices, bandwidth, as well as physical and personal space, families have had to contend with rising tensions around the quality of digital engagement, children’s learning abilities, parent-child relationships and overall familial wellbeing. This fraught situation shone the spotlight on the household context of technology use but also enabled us to marshal academic insights to advance advocacy and public education. The pandemic …

Cardio-Pulmonary Sequelae In Recovered Covid-19 Patients: Considerations For Primary Care, Zouina Sarfraz, Azza Sarfraz, Alanna Barrios, Radhika Garimella, Asimina Dominari, Manish Kc, Krunal Pandav, Juan C. Pantoja, Varadha Retnakumar, Ivan Cherrez-Ojeda

Department of Paediatrics and Child Health

Background: Current literature lacks characterization of the post-recovery sequelae among COVID-19 patients. This review characterizes the course of clinical, laboratory, radiological findings during the primary infection period, and the complications post-recovery. Primary care findings are presented for long-COVID care.
Methods: Adhering to PRISMA guidelines, 4 databases were searched (PubMed, Embase, CINAHL Plus, Scopus) through December 5, 2020, using the keywords "COVID-19 and/or recovered and/or cardiovascular and/or long-term and/or sequelae and/or sub-acute and/or complication." We included published peer-reviewed case reports, case series, and cross-sectional studies providing the clinical course of COVID-19 infection, and cardiopulmonary complications of patients who recovered from COVID-19, …

Covid-19 Vaccine-Associated Thrombosis With Thrombocytopenia Syndrome (Tts): A Systematic Review And Post Hoc Analysis, Muhammad Usman Hafeez, Maha Ikram, Zunaira Shafiq, Azza Sarfraz, Zouina Sarfraz, Vikash Jaiswal, Muzna Sarfraz, Ivan Chérrez-Ojeda

Department of Paediatrics and Child Health

Background: A new clinical syndrome has been recognized following the COVID-19 vaccine, termed thrombosis with thrombocytopenia syndrome (TTS). The following systematic review focuses on extrapolating thrombotic risk factors, clinical manifestations, and outcomes of patients diagnosed with TTS following the COVID-19 vaccine.
Methods: We utilized the World Health Organization's criteria for a confirmed and probable case of TTS following COVID-19 vaccination and conducted a systematic review and posthoc analysis using the PRISMA 2020 statement. Data analysis was conducted using SPSS V25 for factors associated with mortality, including age, gender, anti-PF4/heparin antibodies, platelet nadir, D-dimer peak, time to event diagnosis, arterial or …

The Influence Of Coronavirus Disease-2019 (Covid-19) On Parkinson’S Disease: An Updated Systematic Review, Vikash Jaiswal, Danah Alquraish, Zouina Sarfraz, Azza Sarfraz, Shavy Nagpal, Prakriti Singh Shrestha, Dattatreya Mukherjee, Prathima Guntipalli, Diana F. Sánchez Velazco, Arushee Bhatnagar

Department of Paediatrics and Child Health

Background: COVID-19 has affected global communities with multiple neurological complications in addition to other critical medical issues. COVID-19 binds to the host's angiotensin-converting enzyme 2 (ACE2) receptors, which are expressed in the neurons and glial cells, acting as an entry port to the central nervous system (CNS). ACE2 receptors are abundantly expressed on dopamine neurons, which may worsen the prognosis of motor symptoms in Parkinson's disease (PD). SARS-CoV-2 may lead to an indirect response via immune-mediated cytokine storms and propagate through the CNS leading to damage. In this systematic review, we aim to provide thorough analyses of associations between COVID-19 …

Teleneurology Based Management Of Infantile Spasms During Covid-19 Pandemic: A Consensus Report By The South Asia Allied West Syndrome Research Group, Priyanka Madaan, Jitendra Kumar Sahu, Jithangi Wanigasinghe, Kanij Fatema, Kyaw Linn, Mimi Lhamu Mynak, Nicolás Garófalo Gómez, Pauline Samia, Prakash Poudel, Prem Chand

Department of Paediatrics and Child Health

With telehealth services rescuing patients with chronic neurological disorders during the COVID-19 pandemic, there is a need for simplified teleneurology protocols for neurological disorders in children. Infantile spasms is an epileptic encephalopathy where treatment lag is a significant predictor of outcome. It is one such condition where telemedicine can make a remarkable difference when in-person consultations are delayed or are not possible. However, the adverse effect profile of the first-line therapeutic options, the need for frequent follow-up, underdeveloped telemedicine services, lack of a rational protocol, poor awareness about infantile spasms, a lesser level of parental understanding, and scarcity of pediatric …

Understanding And Promoting Racial Diversity In Healthcare Settings To Address Disparities In Pandemic Crisis Management, Azza Sarfraz, Zouina Sarfraz, Alanna Barrios, Kuchalambal Agadi, Sindhu Thevuthasan, Krunal Pandav, Manish Kc, Muzna Sarfraz, Pedram Rad, George Michel

Department of Paediatrics and Child Health

Background: Health disparities have become apparent since the beginning of the COVID-19 pandemic. When observing racial discrimination in healthcare, self-reported incidences, and perceptions among minority groups in the United States suggest that, the most socioeconomically underrepresented groups will suffer disproportionately in COVID-19 due to synergistic mechanisms. This study reports racially-stratified data regarding the experiences and impacts of different groups availing the healthcare system to identify disparities in outcomes of minority and majority groups in the United States.
Methods: Studies were identified utilizing PubMed, Embase, CINAHL Plus, and PsycINFO search engines without date and language restrictions. The following keywords were used: …

The Stressors Faced By Retail Workers During The Covid-19 Pandemic, Nada Elnahla, Leighann C. Neilson

AMTP Proceedings 2021

Amidst the COVID-19 pandemic, brick-and-mortar retail workers have been hailed as heroic frontline employees. No matter where a retail store is located or the severity of the lockdown, retail workers have many new regulations and guidelines to follow and implement in order to protect both themselves and their customers. Using a qualitative research methodology, this exploratory research focuses on how the COVID-19 pandemic and its resulting drastic changes in the retail sector are affecting the workers in North America. Four main stressors are identified: fear of the unknown, fear of infection, mistreatment by consumers, and the role of the powerless …

The Impact Of Rurality, Underlying Cardiovascular Disease, And Socioeconomic Vulnerability On Covid-19 Outcomes In Georgia, Michael C. Morgan, Lavannya Atri, Jennifer L. Waller, Douglas Miller, Adam E. Berman

Journal of the Georgia Public Health Association

Background: COVID-19 related illnesses have been associated with an increased prevalence of cardiovascular disease sequelae and worsened socioeconomic variables. We sought to investigate the relationship between COVID-19 outcomes, underlying cardiovascular disease, and socioeconomic determinants of health in rural and non-rural counties in the state of Georgia.

Methods: COVID-19, demographic, and socioeconomic data were acquired from publicly available databases including the Center for Disease Control and Prevention’s Social Vulnerability Index (SVI). The relationship between COVID-19 outcomes and markers of cardiovascular disease burden, rurality, and socioeconomic determinants of health was assessed at the county level in Georgia through the beginning of …

Strategic Implications Of Covid-19: Considerations For Georgia’S Rural Health Providers, Bettye A. Apenteng, Linda G. Kimsey, Charles F. Owens, Samuel T. Opoku, Angela Peden, William A. Mase

Journal of the Georgia Public Health Association

Whether rural hospitals and providers have seen a surge in COVID-19 cases or a reduction in patients seeking care since the pandemic began, their financial condition has been negatively impacted. Many providers have now received some emergency funding through the Coronavirus Aid, Relief, and Economic Security Act and the Payroll Protection Program but these are likely only short-term fixes. For many, the crisis has exacerbated already existing problems. Notable among these problems are volume declines, supply chain disruptions, and workforce concerns. While these problems require immediate action, two longer-term systemic changes to rural healthcare delivery are needed to address them. …

The Interplay Of Policy, Behavior, And Socioeconomic Conditions In Early Covid-19 Epidemiology In Georgia, Mallory J. Harris, Ella Tessier-Lavigne, Erin Mordecai

Journal of the Georgia Public Health Association

Publishing Note: This article has been published in its peer-reviewed and accepted form as a post-print version. The fully formatted version of the article will be published on this record when it is available.

ABSTRACT

Background: As COVID-19 began to spread worldwide, local socioeconomic and health factors and nonpharmaceutical interventions may have affected epidemiological outcomes. To investigate the associations between public health orders, behavior, and population factors, and early epidemic dynamics, we investigated variation among counties in the U.S. state of Georgia. There, a large early outbreak occurred in March 2020 with varying levels of local nonpharmaceutical interventions prior to …

Online Medical Education And Examinations During Covid-19: Perspectives Of A Teaching Associate, Syed Mujtaba Baqir, Fatima Mustansir

Department of Biological & Biomedical Sciences

The novel coronavirus disease 2019 (COVID-19) pandemic has not only challenged global health systems but also social, economic, and educational systems. In this short communication, our focus is on its impact on medical education in Pakistan. We discuss the structure of undergraduate medical education in Pakistan; and how it has evolved in the wake of COVID-19. We describe our role as teaching associates (TAs) at the Aga Khan University (AKU); and how it has enabled us to be a part of the transition to online medical education, with a specific focus on online examinations in medical schools.

The Hr Connection, Georgia Southern University

Human Resources (2010-2023)

• COVID-19 Manager's Guide
• Policy Updates
• Ahead Of Phase 1A+ of Vaccine Administration
• January Wellness Corner
• Introducing Percipio
• State Business Transactions Disclosure Reports

Containment & Covid-19 In The Settler State: Indigenous Incarceration And Immigration Detention In Canada And Australia, Kate Motluk

Theses and Dissertations (Comprehensive)

Canada and Australia each have long histories of containing Indigenous peoples and migrants. The overincarceration of Indigenous peoples continues to worsen in both countries, despite targeted reforms. Migrant detention is on the rise worldwide, with Canada and Australia’s systems understood as among the harshest. This thesis explores why Canada and Australia contain these populations by examining these practices through the lens of contemporary settler colonialism. Like most everything, containment by states has undergone rapid changes as a result of the COVID-19 pandemic. This study aims to understand how COVID-19 impacted those within carceral institutions, and contextualize that treatment within the …

Paying Americans To Take The Vaccine - Would It Help Or Backfire?, Christopher Robertson, Daniel Scheitrum, K. Aleks Schaefer, Trey Malone, Brandon R. Mcfadden, Kent D. Messer, Paul J. Ferraro

Faculty Scholarship

This research investigates the extent to which financial incentives (conditional cash transfers) would induce Americans to opt for vaccination against COVID-19. We performed a randomized survey experiment with a representative sample of 1,000 American adults in December 2020. Respondents were asked whether they would opt for vaccination under one of three incentive conditions ($1,000, $1,500, or $2,000 financial incentive) or a no-incentive condition. We find that—without coupled financial incentives—only 58% of survey respondents would elect for vaccination. A coupled financial incentive yields an 8-percentage-point increase in vaccine uptake relative to this baseline. The size of the cash transfer does not …

Park Agency Social Media Communication During The Covid-19 Crisis, Raluca Oprean

Theses and Dissertations (Comprehensive)

The COVID-19 pandemic has affected all industries and organizations, including park agencies. There is a lack of research on how park agencies utilize Twitter during times of crisis, specifically during the COVID-19 pandemic. How park agencies communicate with the public and how they use their social media has not been extensively studied. In addition, the coronavirus pandemic is a novel management issue for these agencies, and there has been no empirical analysis in the ways in which information is being communicated to the public or how that information is being perceived.

This study aims to better understand park agency response …

Covid-19 And The Correctional Environment: An Analysis Of Canadian Correctional Officers’ Experiences Of Stress And Mental Health During The Pandemic, Kristina Kocsis

Theses and Dissertations (Comprehensive)

This national survey research project examined the experiences of Canadian correctional officers (COs) in providing essential correctional services during the COVID-19 pandemic. The study sampled COs from several provinces across Canada (N=596) to better understand how the pandemic impacted stress and wellbeing of this population by exploring seven constructs including resiliency, workplace safety, changes in role or responsibilities, work stress, COVID- 19 related stress, perceived support, and positive mental health. The transactional model of stress and coping and the biopsychosocial model of stress were used as theoretical frameworks to investigate stress responses among COs. Respondents reported significant changes to their …

Evaluating Employees’ Experiences In Implementing Covid-19 Safety Protocols In Ontario Parks, Jessica Kaatz

Theses and Dissertations (Comprehensive)

The COVID-19 pandemic has created a wide range of public health challenges for park management and staff in Ontario. Green spaces have become a source of resilience during the spread of the virus, partly due to their proven positive impacts on social, mental and physical well-being. With the introduction of social distancing protocols, utilization of Personal Protective Equipment (PPE), and standardizing constant sanitation efforts, park employees are more responsible than ever for the daily implementation of rules governing park safety and security. At the same time, increased visitor numbers and continually changing government protocols that varied between regional jurisdictions have …

Covid-19 And Its Impact(S) On Innovation, Clark Asay, Stephanie Plamondon Bair

Faculty Scholarship

In previous work, we explored how certain characteristics of adversity are often more conducive to innovation than others. In this Article, prepared as part of the Lee E. Teitelbaum Utah Law Review Symposium—The Law & Ethics of Medical Research, we review some of that work and apply it specifically to the COVID-19 context. We conclude by assessing certain policy implications in light of how the COVID-19 pandemic has both spurred and hindered innovation.

A Comparative Visual Content Analysis Of The Cdc And Who Covid-19 Infographics, Manushri Pandya

Masters Theses

"In this study, I conducted a comparative visual content analysis of the CDC and WHO COVID-19 infographics. I considered infographics as an important genre of communication during such times because they not only provided sufficient information to the audience but did so in an engaging manner. The goal of my study was to think about the role of infographics in the context of health and risk communication during a pandemic, and to emphasize on the rhetorical elements that constitute the creation of infographics by major health organizations. I specifically focused on three elements: the kinds of information communicated through infographics, …

Health Information Beyond Pandemic Emergencies: Privacy For Social Justice, Leslie Francis

American University Law Review

The COVID-19 pandemic has forcefully revealed the critical importance of timely information to identify emerging infections, discern patterns of disease, and stop disease spread. Information about individuals both as patients, and as ordinary people in the world is necessary for each of these tasks. Yet the implications for information use and efforts to achieve social justice are significant.

This Article first surveys information needs as revealed by the pandemic. It then articulates different normative approaches to privacy and confidentiality to develop two implications for privacy and justice: that information gleaned in clinical care and information possessed by public health should …

National Legal Paradigms For Public Health Emergency Responses, James G. Hodge Jr.

American University Law Review

The COVID-19 pandemic has exposed significant weaknesses of the U.S. federalist system in controlling major infectious disease threats. At the root of American failures to adequately respond is a battle over public health primacy in emergency preparedness and response. Which level of government—federal or state—should actually “call the shots” to quell national emergencies? Constitutional principles of cooperative federalism suggest both levels of government are responsible. Yet real-time applications of these principles, coupled with dubious national leadership, contributed to horrific public health outcomes across America. No one seeks a repeat performance of U.S. COVID-19 response efforts to forthcoming major health threats. …

Disease And Data In Society: How The Pandemic Expanded Data Collection And Surveillance Systems, Alan Butler, Enid Zhou

American University Law Review

The COVID-19 pandemic1 is a global tragedy of historic proportions, and its impacts on our families, communities, and social structures will be felt for many years to come. From the significant to the mundane, COVID-19 has changed many aspects of daily life. One of the less obvious but more long-lasting changes may well be the expansion of data collection and surveillance systems adopted both in response to, and as a result of, the pandemic.