Digital Commons Network^™

Long Term Effects On Health: Analyzing The Lasting Effects Of Covid-19 On The Human Body, Kaylie Stachelski

University Honors College

The ongoing COVID-19 pandemic has raised concerns regarding the long-term effects it can leave on an individual’s health. This abstract provides an overview of the emerging evidence of the long-term effects of COVID-19. Research indicates that COVID-19 can lead to acute or chronic health effects, affecting multiple systems in the body. The symptoms that have been known to effect quality of life in patients that have been suffering from long-haul COVID. While the full spectrum and mechanisms of long-term effects are still under investigation, understanding and addressing the long-term health consequences of COVID-19 remain critical for patient care and public …

Phenomenological Study Of The Impact Of Stress And Burnout After Covid-19 On Educators: Supporting Teachers In Resiliency And Facilitating Adversarial Growth Post-Pandemic., Rebecca Hicks-Hawkins

Electronic Theses and Dissertations

COVID-19 has not only caused anxiety and fears among teachers for their own health and that of their families; they are also facing increased responsibility. Planning periods had been replaced with coverage periods, where teachers must teach other classes when their colleagues are out—often due to illness—because the supply of substitute teachers cannot meet the demand (Barton & Dickason, 2022). Teaching is a demanding profession, and there will always be stress associated with a job where so many external factors come into play (Hansen, 2013). However, in the face of adversity some teachers were thriving. They are showing up and …

Mivacunala (Myshotla): A Community-Partnered Mobile Phone Intervention To Improve Covid-19 Vaccination Behaviors Among Low-Income, Spanish-Speaking, And Immigrant Latino Parents Or Caregivers, Yelba M. Castellon-Lopez, Alexandra M. Klomhaus, Cruz Garcia, Denise Marquez, Hilda Avila, Hannah Gravette, Ray Lopez-Chang, Brenda Ortega, Keith C. Norris, Arleen F. Brown, Luisa Blanco

All Faculty Open Access Publications

We developed and tested MivacunaLA/MyshotLA, a community-informed mobile phone intervention, to increase COVID-19 vaccination among Latino parents/caretakers of minors in under-resourced areas of Los Angeles by addressing misinformation and building trust. We recruited Latino parents/caregivers with at least one unvaccinated child in East and South Los Angeles in the summer of 2021 and evaluated MivacunaLA as a randomized controlled trial with a wait-list control group. A difference-in-difference analysis showed Latino parents/caregivers that participated in MivacunaLA (n = 246), in comparison to the control group, were 15 percentage points more likely (p = 0.04) to report vaccination of minors aged 12–17 …

Assessing Covid-19 Deaths By Occupation And Race: Louisiana 2020-2021, Anna Reilly, Brittany Babin, Rashanda Littles, Susanne Straif-Bourgeois

Journal of the Louisiana Public Health Association

Background: The COVID-19 pandemic underscored significant health disparities, with social determinants such as living conditions and occupation amplifying the risk for severe outcomes in Black residents. This study examines the intersection of occupation, race, and COVID-19 mortality among Louisiana workers in 2020 and 2021, emphasizing the importance of integrating work-related information into public health surveillance. Methods: Occupation and race were collected from the death certificates of Louisiana resident workforce participants aged 18-70 years with COVID-19 listed as a cause of death for 2020 and 2021. COVID-19 mortality rates per 100,000 workers were calculated and compared using rate ratios for occupational …

Uncovering Insights On Remote Learning Through A Critical Discourse Analysis Of Tweets At The Start Of The Pandemic In The United States, Douglas Wayne Bridges

Theses and Dissertations

This dissertation examines the discourses surrounding remote learning during the initial stages of the COVID-19 pandemic through Twitter conversations. Employing a Critical Discourse Analysis informed by Michel Foucault’s theories of discourse and power, this study explores how the pandemic has transformed educational interactions over social media platforms. It particularly focuses on the relationships between language, power, and social structures, highlighting the transformative potentials of remote learning amidst a global crisis.

The research reveals how discourse on Twitter reflects broader societal and cultural dynamics, serving as a microcosm of the shifts within the educational sector. Analysis of Twitter threads, retweets, and …

The Role Of Cosmopolitan Orientation In Covid-19-Related Attitudes: Perceived Threats And Opportunities, Vaccination Willingness, And Support For Collective Containment Efforts, Angela K. Y. Leung, Brandon Koh, Verity Yu Qing Lua, James H. Liu, Sarah Y. Choi, I-Ching Lee, Michelle Lee, Mei-Hua Lin, Darrin Hodgetts, Sylvia X. Chen

Research Collection School of Social Sciences

Cosmopolitan individuals identify themselves as "citizens of the world." In the present research, we tested the idea that endorsing a cosmopolitan orientation (CO) is adaptive in the COVID-19 crisis. Cosmopolitan individuals more readily transcend national parochialism, show greater concern for all humanity, and prioritize collective interests. In a two-wave multi-region investigation with six samples from China, Hong Kong, Taiwan, Malaysia, Singapore, and the U.S., we first established longitudinal and cross-cultural measurement invariance of the CO scale. Next, we found that people with a higher CO tended to perceive over time a greater threat posed by COVID-19, take more safety measures, …

Covid-19 And Unemployment Dynamics: A Regional Analysis In The United States, Keesha Queenie St. John

Theses

The influence of the COVID-19 pandemic on unemployment rates in several US locations is examined in this research article. We investigate the intricate relationships between COVID-19 cases, mortality, GDP per capita, and unemployment rates through a thorough study of the data. The study sheds insight into the complex interaction between health crises and labor markets by revealing considerable differences in how these factors affect unemployment in various geographic locations.Unexpectedly, key findings show that places with higher COVID-19 cases frequently have lower unemployment rates. This trend is related to several variables, including critical sectors and public health activities. The positive correlation …

The Evolution Of School Leadership In Times Of Crisis, Christopher Butcher, Todd Mccardle

Journal of Excellence in College Teaching and Learning

This case study seeks to address how COVID-19 has affected principals. We approach this study through the lens of Open Systems Theory (Katz & Kahn, 1978), as we attempt to understand how school leaders understand and act during a global pandemic. This research answers the following question: How has the role of a school principal changed since the onset of COVID-19? The data reveal two emerging themes: 1) principals taking on unique caretaker roles and 2) principals increasing their focus on a managerial approach to leadership. The findings support the evolution (and devolution) of leadership approaches that school principals go …

The Educator Labor Market In Times Of Change: Lessons From The Covid-19 Pandemic, Andrew Mitchell Camp

Graduate Theses and Dissertations

The COVID-19 pandemic placed an undeniable burden onto the teaching profession which already faced levels of prestige and interest at 50-year lows. The strains of the pandemic resulted in educators reporting higher levels of job-related stress and burnout and exacerbated concerns about potential teacher shortages. This dissertation leverages administrative data from Arkansas to better understand challenges facing the teacher workforce following COVID-19 and evaluate two increasingly policies aimed at the teacher workforce. In the first chapter, I provide evidence that teacher turnover was relatively stable during the first two years (2020-21 and 2021-22) of the COVID-19 pandemic before a notable …

Covid 19 And Classroom Instruction: A Comparison Of Synchronous In-Person And Virtual Student Learning, Jason Brown

Electronic Theses and Dissertations

The purpose of this ex-post facto quantitative study was to compare English Language Arts (ELA) and math Tennessee Compressive Assessment Program (TCAP) scores of students in grades four through eight who attended school virtually or in-person during the 2020-2021 school year. Due to the COVID-19 pandemic, the school district in this study allowed parents to choose to send their children to traditional in-person classes or attend school virtually. In-person and virtual students engaged synchronous classroom instruction through Google Meets. All virtual students were instructed by the teachers they would have had if their parents had chosen to send them for …

Navigating School Restructuring In The Post-Covid Era: A Principal’S Perspective In Sustaining Organizational Health While Bridging The Academic Achievement Gap, Alma Alicia Perez-Campos

Theses and Dissertations

In 2019, the COVID-19 pandemic led to nationwide school closures, followed by a mandate for schools to reopen in 2020, posing challenges for ensuring both educational continuity and student safety. This paper presents findings from a mixed-method study involving ten campus principals in District A, South Texas, post-pandemic. Qualitatively, the study explored the principals' perspectives on restructuring their campuses to address achievement gaps while maintaining organizational health. Quantitatively, it examined the relationship between achievement and organizational health scores and any differences in organizational health pre- and post-COVID-19. The study aimed to offer insights for future …

A Cross-Sectional Analysis Of Self-Reported Long Covid And Binge Drinking Amongst Covid-Positive Individuals Using The Behavioral Risk Factor Surveillance System (Brfss), 2022, Maire Kirley

Capstone Experience: Master of Public Health

Objective: Identify an association between Long COVID (exposure) and binge drinking (outcome) amongst COVID-positive individuals.

Methods: COVID-positive respondents (n=116,120) were sampled from the 2022 Behavioral Risk Factor Surveillance System (BRFSS). Univariate analysis assessed distribution of Long COVID, binge drinking, and covariates sex, age, race/ethnicity, education, income, rural/urban residency, veteran status and BMI. Bivariate analysis determined crude prevalence odds ratios (POR) between exposure, outcome, and covariates. Multivariate logistic regression determined adjusted prevalence odds ratios (aPOR) and 95% confidence intervals (95% CI) for exposure, outcome and covariates.

Results: No association found between Long COVID and binge drinking (aPOR: 0.94 (95% CI: 0.87, …

Factors Associated With The Ability Of Us Nursing Homes To Accept Residents With Severe Obesity, Cynthia Mcmahan, Bianca Shieu, Alison Trinkoff, Nicholas Castle, David G Wolf, Steven Handler, John A Harris

Faculty, Staff and Student Publications

Objectives: Severe obesity in nursing home (NH) residents is associated with specialized care needs, limited mobility, and challenges in daily living. The COVID-19 pandemic strained NH resources and exacerbated staffing shortages. This study aimed to assess the ability of US NHs to accept and care for residents with severe obesity post-COVID, as well as associated NH factors.

Design: Cross-sectional nationwide survey of NH administrators (2021-2022).

Setting and participants: 290 NHs from a national sample (n = 224) and a targeted sample in Massachusetts and New Jersey (n = 66).

Methods: A survey designed to assess how NHs approach admitting and …

Assessing The Impact Of The Covid-19 Pandemic On Training At The Md Anderson Cancer Center Anatomical Pathology Fellowship Program, Yiannis P Dimopoulos, Donghyang Kwon, Denái R Milton, Paula I Iaeger, Donna E Hansel, Victor G Prieto, Kareen E Chin, Phyu P Aung

Faculty, Staff and Student Publications

Context: To provide high-quality, safe training during the COVID-19 pandemic, our anatomic pathology fellowship program implemented a hybrid virtual/in-person training model with supplemental digital material.

Objective: To evaluate the impact of this model.

Design: We examined Accreditation Council for Graduate Medical Education survey results and board pass rates for fellows before the pandemic (group 1); during the pandemic peak (group 2); and early and late after the pandemic peak (groups 3 and 4). Additionally, we distributed an online survey, including questions related to performance as attending physicians and fellowship experience, to recent graduates.

Results: Information loss during handover, supervision and …

Sars-Cov-2 Viral Load In The Nasopharynx At Time Of First Infection Among Unvaccinated Individuals, Leigh H Fisher, Jia Jin Kee, Albert Liu, Claudia M Espinosa, April K Randhawa, James Ludwig, Craig A Magaret, Samuel T Robinson, Peter B Gilbert, Ollivier Hyrien, James G Kublin, Nadine Rouphael, Ann R Falsey, Magdalena E Sobieszczyk, Hana M El Sahly, Beatriz Grinsztejn, Glenda E Gray, Karen L Kotloff, Cynthia L Gay, Brett Leav, Ian Hirsch, Frank Struyf, Lisa M Dunkle, Kathleen M Neuzil, Lawrence Corey, Yunda Huang, Paul A Goepfert, Stephen R Walsh, Lindsey R Baden, Holly Janes, Covid-19 Prevention Network (Covpn)

Faculty, Staff and Student Publications

Importance: SARS-CoV-2 viral load (VL) in the nasopharynx is difficult to quantify and standardize across settings, but it may inform transmission potential and disease severity.

Objective: To characterize VL at COVID-19 diagnosis among previously uninfected and unvaccinated individuals by evaluating the association of demographic and clinical characteristics, viral variant, and trial with VL, as well as the ability of VL to predict severe disease.

Design, setting, and participants: This secondary cross-protocol analysis used individual-level data from placebo recipients from 4 harmonized, phase 3 COVID-19 vaccine efficacy trials sponsored by Moderna, AstraZeneca, Janssen, and Novavax. Participants were SARS-CoV-2 negative at baseline …

Correlation Between Il-6 And Age In Covid-19: Insights From A Cross-Sectional Analysis In Malang, Indonesia, Agustin Iskandar, Dearikha Karina Mayashinta, Catur Suci Sutrisnani, Nur Samsu, Agustina Tri Endharti, Edy Widjajanto

Baghdad Science Journal

Interleukin 6 (IL-6) has been identified as a predictor of severity and mortality in COVID-19. Although morbidity and mortality generally increase with age, it remains uncertain whether there is a correlation between age and IL-6 levels, thereby exacerbating the severity of COVID-19 in patients. The objective of this study was to examine the correlation between age and IL-6 levels in COVID-19 patients. The study was cross-sectional, analyzing laboratory and medical records of 3,171 COVID-19 patients who received treatment in 2021 at Saiful Anwar General Hospital. The Data analyzed using Kruskal-Wallis, Dunnett's Post Hoc, and Spearman Correlation tests. The patients were …

Understanding Stress And Coping Among Adults In The United States During The Covid-19 Pandemic, Jocy-Anna Chevalier

UNLV Theses, Dissertations, Professional Papers, and Capstones

Since the COVID-19 pandemic started, individuals in the United States (U.S.) and across the globe have experienced unprecedented levels of stress. The purpose of this study is to understand the stress experienced among adults in the U.S. and which coping processes affect their overall emotional well-being. Guided by Lazarus and Folkman’s (1987) Transactional Model of Stress and Coping (TMSC), this study conducted a secondary data analysis (n=404) of adults across the U.S who completed an online survey examining their experiences with stress and coping. A Pearson correlation was utilized to explore the relationship between stress and depressive symptoms. Paired samples …

Vitamin D Regulates Covid-19 Associated Severity By Suppressing The Nlrp3 Inflammasome Pathway, Bariaa Khalil, Narjes Saheb Sharif-Askari, Shirin Hafezi, Fatemeh Saheb Sharif-Askari, Fatme Al Anouti, Qutayba Hamid, Rabih Halwani

All Works

Background The role of vitamin D3 (VitD3) in modulating innate and adaptive immunity has been reported in different disease contexts. Since the start of the coronavirus disease-2019 (COVID-19) pandemic, the role of VitD3 has been highlighted in many correlational and observational studies. However, the exact mechanisms of action are not well identified. One of the mechanisms via which VitD3 modulates innate immunity is by regulating the NLRP3-inflammasome pathway, being a main underlying cause of SARS-CoV-2-induced hyperinflammation. Aims and main methods Blood specimens of severe COVID-19 patients with or without VitD3 treatment were collected during their stay in the intensive care …

Post-Covid Small Fiber Neuropathy, Implications Of Innate Immunity, And Challenges On Ivig Therapy, Marinos Dalakas

Department of Neurology Faculty Papers

No abstract provided.

Burnout And Work Fatigue In Contingent Faculty During The Covid-19 Pandemic, Gina Dimartino

Dissertations

The COVID-19 pandemic and immediate shift to remote learning had a major impact on faculty and students in higher education institutions (HEIs). As a result of the pandemic, many stakeholders in HEIs have experienced burnout and work fatigue, specifically, contingent/adjunct faculty. Contingent/adjunct faculty comprise a majority of faculty who serve students in colleges and universities across the country.

As the needs of students increased during the pandemic, contingent/adjunct faculty experienced increased workloads due to the additional support needed by diverse and challenged students. This further intensified the unique challenges faced by contingent faculty that existed prior to the pandemic in …

Examining The Association Between Smoking Frequency And Long Covid: A Brfss Study, Bhavya Patel

Capstone Experience: Master of Public Health

Objectives: To examine the relationship between self-reported smoking frequency and the presence of Long COVID among individuals who tested positive for COVID-19.

Methods: A cross-sectional study was conducted using a sample of 44,738 COVID-positive participants from the 2022 Behavioral Risk Factor Surveillance System (BRFSS) dataset. Logistic regression was utilised to compute prevalence odds ratios (pOR) and was adjusted for potential sociodemographic confounders.

Results: Individuals who smoked daily were found to have a greater likelihood of reporting Long COVID in comparison with nonsmokers (Crude pOR=1.22; CI= [1.10-1.35]). However, in the adjusted regression model, daily smoking was no longer significant (Adjusted pOR=1.04; …

Targeted Accurate Rna Consensus Sequencing (Tarc-Seq) Reveals Mechanisms Of Replication Error Affecting Sars-Cov-2 Divergence, Catherine C Bradley, Chen Wang, Alasdair J E Gordon, Alice X Wen, Pamela N Luna, Matthew B Cooke, Brendan F Kohrn, Scott R Kennedy, Vasanthi Avadhanula, Pedro A Piedra, Olivier Lichtarge, Chad A Shaw, Shannon E Ronca, Christophe Herman

Duncan NRI Faculty and Staff Publications

RNA viruses, like SARS-CoV-2, depend on their RNA-dependent RNA polymerases (RdRp) for replication, which is error-prone. Monitoring replication errors is crucial for understanding the virus’s evolution. Current methods lack the precision to detect rare de novo RNA mutations, particularly in low-input samples such as those from patients. Here, we introduce a new targeted Accurate RNA Consensus sequencing method (tARC-seq) to accurately determine the mutation frequency and types in SARS-CoV-2, both in cell culture and clinical samples. Our findings show an average of 2.68×10−5 new errors per cycle with a C>T bias that cannot be solely attributed to APOBEC …

Unmasking Justice: Racial Disparity Trends In Sentencing Before And After The Covid-19 Pandemic, Noah Samuel Reynolds

All Theses

The advent of the COVID-19 pandemic profoundly impacted every facet of the United States justice system, disrupting traditional systems and introducing a new era of virtual alternatives. This unprecedented crisis provides a unique opportunity to empirically study the interplay between health risks, shutdowns, and uncertainty and the foundational value of fair and impartial justice. Using North Carolina sentencing data from 2016-2022, this study delves into the consequences of the pandemic on sentencing outcomes after the virus was declared a national emergency in March 2020. Framed within the Focal Concerns (FC) theory, I expect judges to be more lenient in their …

Depression And Anxiety: Investigating The Impacts Of Scheduling On The Mental Health Of Healthcare Workers During The Covid-19 Pandemic, Christofer Gonzaga

All Theses

Depression is a growing problem in the United States and has ballooned into a globally recognized mental health issue that affects shift workers in various fields (Lee et al., 2017). Rates of depression and anxiety have been shown to be substantially increasing and the COVID-19 pandemic amplified this prevalence of depression and anxiety. In the United States, the prevalence of depression symptoms was more than 3- fold higher during COVID-19 compared to before the pandemic (Ettman et al., 2020). The delivery of healthcare services is an ongoing and dynamic process, requiring clinicians to work in various shifts to ensure the …

Personal Green Spaces During The Pandemic - Perceptions Towards Urban Home Gardens During The Covid-19 Pandemic In Bengaluru, India, Varsha Bhaskaran, Charles Nilon

Cities and the Environment (CATE)

The COVID-19 pandemic has brought about unprecedented changes in a short span of time to people’s life and living. Being in a lockdown, especially in urban areas, has led to changes in the way people perceive nature around them and within their homes. Research on this topic in the cities of the global south has been limited with even fewer studies in Indian cities. To begin to address this gap, in this exploratory study we interviewed 30 residents of Bengaluru, India to understand how they perceived the changes they experienced in their home gardens and in the nature around their …

Sars-Cov-2 Viral Load In The Nasopharynx At Time Of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis Of 4 Randomized Trials, Leigh H Fisher, Jia Jin Kee, Albert Liu, Claudia M Espinosa, April K Randhawa, James Ludwig, Craig A Magaret, Samuel T Robinson, Peter B Gilbert, Ollivier Hyrien, James G Kublin, Nadine Rouphael, Ann R Falsey, Magdalena E Sobieszczyk, Hana M El Sahly, Beatriz Grinsztejn, Glenda E Gray, Karen L Kotloff, Cynthia L Gay, Brett Leav, Ian Hirsch, Frank Struyf, Lisa M Dunkle, Kathleen M Neuzil, Lawrence Corey, Yunda Huang, Paul A Goepfert, Stephen R Walsh, Lindsey R Baden, Holly Janes, Covid-19 Prevention Network (Covpn)

Faculty, Staff and Students Publications

IMPORTANCE: SARS-CoV-2 viral load (VL) in the nasopharynx is difficult to quantify and standardize across settings, but it may inform transmission potential and disease severity.

OBJECTIVE: To characterize VL at COVID-19 diagnosis among previously uninfected and unvaccinated individuals by evaluating the association of demographic and clinical characteristics, viral variant, and trial with VL, as well as the ability of VL to predict severe disease.

DESIGN, SETTING, AND PARTICIPANTS: This secondary cross-protocol analysis used individual-level data from placebo recipients from 4 harmonized, phase 3 COVID-19 vaccine efficacy trials sponsored by Moderna, AstraZeneca, Janssen, and Novavax. Participants were SARS-CoV-2 negative at baseline …

Texture-Based Classification To Overcome Uncertainty Between Covid-19 And Viral Pneumonia Using Machine Learning And Deep Learning Techniques, Omar Farghaly, Priya Deshpande

Electrical and Computer Engineering Faculty Research and Publications

The SARS-CoV-2 virus, responsible for COVID-19, often manifests symptoms akin to viral pneumonia, complicating early detection and potentially leading to severe COVID pneumonia and long-term effects. Particularly affecting young individuals, the elderly, and those with weakened immune systems, the accurate classification of COVID-19 poses challenges, especially with highly dimensional image data. Past studies have faced limitations due to simplistic algorithms and small, biased datasets, yielding inaccurate results. In response, our study introduces a novel classification model that integrates advanced texture feature extraction methods, including GLCM, GLDM, and wavelet transform, within a deep learning framework. This innovative approach enables the effective …

A Study Of Cybersecurity Landscape In The United States: Trend, Regional Variations, And Socioeconomic Factors, Trang Thi Thu Horn

All-Inclusive List of Electronic Theses and Dissertations

The Internet has become an essential part of our daily lives. Cyberspace has emerged significantly with an enormous number of users, creating a lucrative hunting field for cybercriminals. The exponential growth of internet users and online activities, along with the increased sophistication of cybercrimes, is raising significant global concerns for individuals, organizations, and governments. This research aims to explore the cybersecurity landscape in the United States, investigate regional variations, and the potential impact of the COVID-19 pandemic on the number of cybercrimes. The study utilizes a mixed research method approach, including historical analysis and a Delphi study. Historical analysis studied …

Observational Analysis For Predicting Initial Spikes In Testing Volume Of Cohorts Inside And Outside Of A Regional Covid-19 Screening Program, Adam M. Franks, Seth Bergeron, Tammy Bannister, Justin Spradling, Tamara Lowe, Paris Johnson, Rajan Lamichhane, Stephen M. Petrany

Marshall Journal of Medicine

BACKGROUND Containing the highly contagious SARs-CoV-2 pathogen requires a safe and effective screening program. The aim of this observational cohort study is to analyze a regional testing center and identify factors predicting testing rates that direct supply and staffing needs.

METHODS A drive-through SAR-CoV-2 regional testing facility was created. Number of tests and positive results were collected for eighteen months. Data for testing demand was compared to positive results, percent positive rates (PPR), known external factors, and county PPR. Dissimilarities were contrasted with dynamic time warp and a detailed agreement analysis. The Grainger’s test was utilized to assess the degree …

Covid-19 In The Setting Of Hiv And Severe Hemophilia A: A Case Report, Ryan Wilson, Chae Ko, Rahul Kashyap

HCA Healthcare Journal of Medicine

Introduction

A hyperactive immune response is the driving force behind severe Coronavirus disease 2019 (COVID-19). Complications of severe COVID-19 include acute respiratory distress syndrome, acute respiratory failure, and increased risk of venous thromboembolism (VTE). The management of patients with COVID-19 includes respiratory support, decreasing immune response to the virus to prevent the progression of disease, and anticoagulation to prevent VTE.

Case Presentation

We present the case of a patient with a history of human immunodeficiency virus (HIV) and hemophilia A admitted with COVID-19. This case demonstrates the difficulties present when managing COVID-19 in patients with specific comorbidities. Anticoagulation is a …