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Articles 1051 - 1080 of 12862
Full-Text Articles in Entire DC Network
Understanding Barriers To Effective And Equitable Covid-19 Response Through The Evaluation Of Essential Needs Program In Jefferson County, Ky., Haritha Pallam
Understanding Barriers To Effective And Equitable Covid-19 Response Through The Evaluation Of Essential Needs Program In Jefferson County, Ky., Haritha Pallam
Electronic Theses and Dissertations
This study utilized a multi-method study approach to assess the effectiveness of the Essential Needs Program (ENP), aimed at aiding priority groups in successfully completing isolation or quarantine (I/Q) during the COVID-19 pandemic. It commences with an overview of the COVID-19 pandemic's history and the role of ENP as a local emergency response strategy to mitigate community spread. Chaos and systems theories were employed to comprehensively understand disaster phenomena and factors influencing individual adoption of protective measures during the pandemic. Additionally, institutional decision-making models and implementation science were utilized to elucidate how public health stakeholders coordinated ENP services provision and …
Safety And Feasibility Of Third-Party Cytotoxic T Lymphocytes For High-Risk Patients With Covid-19, Dolores Grosso, John L. Wagner, Allyson O'Connor, Kaitlyn Keck, Yanping Huang, Zi-Xuan Wang, Hilary Mehler, Benjamin Leiby, Phyllis Flomenberg, Usama Gergis, Neda Nikbakht, Michael Morris, Julie Karp, Alexis R. Peedin, Neal Flomenberg
Safety And Feasibility Of Third-Party Cytotoxic T Lymphocytes For High-Risk Patients With Covid-19, Dolores Grosso, John L. Wagner, Allyson O'Connor, Kaitlyn Keck, Yanping Huang, Zi-Xuan Wang, Hilary Mehler, Benjamin Leiby, Phyllis Flomenberg, Usama Gergis, Neda Nikbakht, Michael Morris, Julie Karp, Alexis R. Peedin, Neal Flomenberg
COVID-19 Papers, Posters, and Presentations
Cytotoxic T lymphocytes (CTLs) destroy virally infected cells and are critical for the elimination of viral infections such as those caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Delayed and dysfunctional adaptive immune responses to SARS-CoV-2 are associated with poor outcomes. Treatment with allogeneic SARS-CoV-2-specific CTLs may enhance cellular immunity in high-risk patients providing a safe, direct mechanism of treatment. Thirty high-risk ambulatory patients with COVID-19 were enrolled in a phase 1 trial assessing the safety of third party, SARS-CoV-2-specific CTLs. Twelve interventional patients, 6 of whom were immunocompromised, matched the HLA-A∗02:01 restriction of the CTLs and received …
Managing Tourist Booking Intentions: A Study Of Hotel Marketing Strategies During The Covid-19 Crisis In Cyprus, Chrystalla Markou, Giannis Theofanous, Doros Michael
Managing Tourist Booking Intentions: A Study Of Hotel Marketing Strategies During The Covid-19 Crisis In Cyprus, Chrystalla Markou, Giannis Theofanous, Doros Michael
Journal of Global Hospitality and Tourism
This study investigates the impact of specific marketing strategies on tourist booking intentions during the COVID-19 crisis in Cyprus, aiming to understand the effectiveness of these strategies in maintaining booking intentions. The study also investigates the challenge of maintaining tourists’ booking intentions during the financial impact of COVID-19. A quantitative, non-experimental correlational study examined the existence, strength, and direction of the relationship between all-inclusive holiday packages, room discounts, and special hotel amenities and hotel accommodations as measured by intentions to select a hotel in the Cyprus hotel industry. For the purpose of this study, 161 tourists who stayed in Cyprus …
De-Escalation Of Disease-Modifying Therapy For People With Multiple Sclerosis Due To Safety Considerations: Characterizing 1-Year Outcomes In 25 People Who Switched From Ocrelizumab To Diroximel Fumarate., Mark Gudesblatt, Barbara Bumstead, Marijean Buhse, Myassar Zarif, Sarah A Morrow, Jacqueline A Nicholas, Laura M Hancock, Jeffrey Wilken, Joanna Weller, Nicole Scott, Anne Gocke, James B Lewin, Olivia Kaczmarek, Jason P Mendoza, Daniel Golan
De-Escalation Of Disease-Modifying Therapy For People With Multiple Sclerosis Due To Safety Considerations: Characterizing 1-Year Outcomes In 25 People Who Switched From Ocrelizumab To Diroximel Fumarate., Mark Gudesblatt, Barbara Bumstead, Marijean Buhse, Myassar Zarif, Sarah A Morrow, Jacqueline A Nicholas, Laura M Hancock, Jeffrey Wilken, Joanna Weller, Nicole Scott, Anne Gocke, James B Lewin, Olivia Kaczmarek, Jason P Mendoza, Daniel Golan
Neuroscience Articles
INTRODUCTION: Switching disease-modifying therapy (DMT) may be considered for relapsing-remitting multiple sclerosis (RRMS) if a patient's current therapy is no longer optimal. This was particularly important during the recent COVID-19 pandemic because of considerations around immune deficiency and impaired vaccine response associated with B cell-depleting DMTs. This real-world, single-center study aimed to evaluate change or decline in functional ability and overall disease stability in people with RRMS who were switched from B cell-depleting ocrelizumab (OCRE) to diroximel fumarate (DRF) because of safety concern related to the COVID-19 pandemic.
METHODS: Adults with RRMS were included if they had been clinically stable …
Women's Experience Of Cancer Treatment During Covid-19 On The Texas-Mexico Border, Kayla E. Castañeda
Women's Experience Of Cancer Treatment During Covid-19 On The Texas-Mexico Border, Kayla E. Castañeda
Nursing Theses and Dissertations
The COVID-19 pandemic exposed existing racial, ethnic, socioeconomic, geographic, and gender disparities in cancer care and highlighted the need for more research in understudied populations. No studies have elucidated the experience of women living on the Texas-Mexico border receiving cancer treatment during the pandemic. This study explored the lived experience of receiving cancer treatment during the COVID-19 pandemic in 2020 for women living on the Texas-Mexico border and identified participants' self-identified unmet needs while receiving cancer treatment during the COVID-19 pandemic on the Texas-Mexico border. Following IRB approval and informed consent, ten women living on the Texas-Mexico border who received …
The Impact Of The Covid-19 Pandemic On Device-Associated Healthcare-Associated Infections In Nevada, Gabriela Bran
The Impact Of The Covid-19 Pandemic On Device-Associated Healthcare-Associated Infections In Nevada, Gabriela Bran
UNLV Theses, Dissertations, Professional Papers, and Capstones
Healthcare-associated infections or hospital-acquired infections (HAIs) have remained prevalent despite the growth of infection control programs in healthcare facilities and are a large cause of morbidity and mortality. Device-associated HAIs (DA-HAIs) make up a large portion of HAIs. The devices include central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), and ventilator-associated events (VAEs). DA-HAIs became a large concern during the COVID-19 pandemic as many healthcare facilities became overwhelmed by the influx of COVID-19 cases, illuminating the importance of studies to examine these changes. Therefore, this study aimed to evaluate how DA-HAI rates have changed during and after the …
The Influence Of The Covid-19 Pandemic On Binge Eating In A Demographically Diverse Us Community Sample, Jessica H. Habashy
The Influence Of The Covid-19 Pandemic On Binge Eating In A Demographically Diverse Us Community Sample, Jessica H. Habashy
UNLV Theses, Dissertations, Professional Papers, and Capstones
The novel coronavirus pandemic (COVID-19) has had profound effects among many individuals with or at risk for eating disorders. The most common primary eating disorder is binge eating disorder which has uniquely reflected more similarities than differences among diverse populations compared to other eating disorder classifications. Considering the upsurge of prevalence rates of eating disorders during the pandemic, it is important to assess the rate of binge eating across the demographic strata to gain a better understanding of who is impacted and provide healing to those who are suffering. Screening for binge eating features across the United States (US) using …
The Credit Card Behaviors And Financial Satisfaction Among Emerging Adults During The Covid-19 Pandemic, Jessica Ralphs
The Credit Card Behaviors And Financial Satisfaction Among Emerging Adults During The Covid-19 Pandemic, Jessica Ralphs
All Graduate Theses and Dissertations, Fall 2023 to Present
Using data from the 2021 National Financial Capability Study (NFCS), this study focused on poor credit card behaviors and financial satisfaction of emerging adults ages between 18 and 29 (N=1,944). The descriptive results show that 45.8% reported carrying over a balance in the past 12 months and 51.3% reported paying the minimum payment some months. It was also found that 28.3% reported being charged a late fee for late payment some months in the past 12 months, whereas 21.7% reported being charged an over the limit fee for exceeding their credit limit some months.
The multivariate results indicated …
Differences In Debt Holdings And Financial Satisfaction Across Age During Covid, Loryn Elaine Law
Differences In Debt Holdings And Financial Satisfaction Across Age During Covid, Loryn Elaine Law
All Graduate Theses and Dissertations, Fall 2023 to Present
Access to credit has allowed many individuals to reach their own version of the American dream as credit offers them resources to improve quality of life by buying homes, purchasing automobiles, funding higher education, and financing everyday needs. However, accumulating debt may have negative impacts on their financial satisfaction. Since the 2021 wave of the National Financial Capability Study (NFCS) was collected during the COVID-19 Pandemic, this study was able to look at how financial stressors (e.g., unexpected income drops, being laid-off, difficulty paying on-going bills), financial anxiety, and financial literacy variables (e.g., subjective financial knowledge, objective financial knowledge, perceived …
Expanding A Behavioral View On Digital Health Access: Drivers And Strategies To Promote Equity, Maura M Kepper, Lauren A Fowler, Isabelle S Kusters, Jean W Davis, Manal Baqer, Sara Sagui-Henson, Yunyu Xiao, Adati Tarfa, Jean C Yi, Bryan Gibson, Kristin E Heron, Nicole M Alberts, Marissa Burgermaster, Veronica Ps Njie-Carr, Lisa M Klesges
Expanding A Behavioral View On Digital Health Access: Drivers And Strategies To Promote Equity, Maura M Kepper, Lauren A Fowler, Isabelle S Kusters, Jean W Davis, Manal Baqer, Sara Sagui-Henson, Yunyu Xiao, Adati Tarfa, Jean C Yi, Bryan Gibson, Kristin E Heron, Nicole M Alberts, Marissa Burgermaster, Veronica Ps Njie-Carr, Lisa M Klesges
2020-Current year OA Pubs
The potential and threat of digital tools to achieve health equity has been highlighted for over a decade, but the success of achieving equitable access to health technologies remains challenging. Our paper addresses renewed concerns regarding equity in digital health access that were deepened during the COVID-19 pandemic. Our viewpoint is that (1) digital health tools have the potential to improve health equity if equitable access is achieved, and (2) improving access and equity in digital health can be strengthened by considering behavioral science-based strategies embedded in all phases of tool development. Using behavioral, equity, and access frameworks allowed for …
Evolving Community Preparedness: Analysis Of United States Pandemic Health Disaster Readiness, Jessy Rugeyo
Evolving Community Preparedness: Analysis Of United States Pandemic Health Disaster Readiness, Jessy Rugeyo
Theses and Dissertations
The COVID-19 pandemic has shown substantial gaps in counties' preparedness and response capacity across the United States. This study analyzes the relationship between county-level pandemic preparedness and confirmed COVID-19 cases using secondary data from the FEMA's National Household Survey (NHS) and county-level COVID-19 data from the CDC. The data show a negative relationship between preparedness levels and COVID-19 positive rates, highlighting the necessity of proactive readiness measures. Individual risk assessment, motivation for preparedness, and socioeconomic variables have a major influence on confirmed cases. Higher levels of education, income, and preparedness are associated with lower positive rates, emphasizing the importance of …
Economic Development In Legacy Cities: Current And Emerging Challenges And Opportunities, Neil Reid, Sujata Shetty, Jane Adade
Economic Development In Legacy Cities: Current And Emerging Challenges And Opportunities, Neil Reid, Sujata Shetty, Jane Adade
Midwest Social Sciences Journal
As manufacturing employment has declined in the traditional manufacturing regions over the past decades, many communities have experienced population loss and overall economic decline. Local economic development professionals have had to grapple with long-term structural changes in the economy as well as short-term jolts. To gain insights into the changing landscape of economic development, we interviewed economic development practitioners in Indiana, Michigan, Ohio, and Pennsylvania. The interviews focused on their perception of current and emerging challenges and opportunities with respect to economic development in their respective communities. Having identified the major challenges and opportunities, we asked them to articulate the …
Im/Mobilities During The Covid-19 Pandemic: Perspectives From International Graduate Students Studying In The Southern United States, Christina W. Yao, Kaitlyn Hall, Simone Gause, Leslie Jo Shelton
Im/Mobilities During The Covid-19 Pandemic: Perspectives From International Graduate Students Studying In The Southern United States, Christina W. Yao, Kaitlyn Hall, Simone Gause, Leslie Jo Shelton
Educational Sciences and Organizations
The background of this study is situated within the COVID-19 pandemic as an acute challenge with chronic issues that international graduate students have faced continuously. With the pandemic serving as a critical incident, we highlight the political, systemic, and personal fragilities of international graduate students studying in the southern United States. The methods for our study were informed by a narrative inquiry approach combined with a systematic literature review to connect with the conceptual framework of Avison and Turner’s chronic strains and Robertson’s conception of timescales. The findings highlight three broad themes: shifting immigration policies and travel uncertainty, institutional responses, …
Adverse Childhood Experiences And Career Decision Making In College Students: Investigating The Moderating Effects Of Perceived Covid-19 Impact And Ambiguity Tolerance, Kendall Klumpp
Dissertations
College students face many difficult decisions as they navigate adulthood, including making a decision about their career. Although much research has already been conducted to explore these difficulties, little has explored the potential impact of adverse childhood experiences (ACEs) on one’s career-related cognitions. Further, the COVID-19 pandemic has provided a new context in which difficulties with career-related decisions may be exacerbated. Through the lens of psychological stress, the current study examined the responses of 231 undergraduate students using a university-based online participant recruiting site, SONA. It was predicted that level of ACEs would be positively related with levels of negative …
E-Cigarette Use Reasons And Associated E-Cigarette Use Dependence Among College Students: A Longitudinal Examination, Tzung-Shiang Ou, Anne Buu, James J Yang, Hsien-Chang Lin
E-Cigarette Use Reasons And Associated E-Cigarette Use Dependence Among College Students: A Longitudinal Examination, Tzung-Shiang Ou, Anne Buu, James J Yang, Hsien-Chang Lin
Faculty, Staff and Student Publications
Objective: Previous studies have established an understanding of reasons for e-cigarette use and associated e-cigarette use patterns such as use frequency, yet the critical extension to associated e-cigarette dependence outcome remains under-researched. This study used longitudinal data to examine whether the reasons for e-cigarette use predict a higher/lower level of e-cigarette dependence.
Methods: This study recruited college students who were current e-cigarette users from Fall 2019 to Fall 2020 (four semesters) at three public universities in the Midwest and South of the U.S. Those who participated for at least two semesters were included (N = 366). Data were collected using …
Mental Health Of Healthcare Workers In Kosovo During The Covid-19 Pandemic, Latif Hoxha
Mental Health Of Healthcare Workers In Kosovo During The Covid-19 Pandemic, Latif Hoxha
All Dissertations
ABSTRACT
This study explored the mental health of healthcare practitioners in Kosovo during the COVID-19 pandemic, focusing on the prevalence of stress, depression, and anxiety, and the associated individual, family, and work-related factors. The research employed a cross-sectional design with a sample of 449 healthcare workers from two hospitals in Kosovo. The Depression, Anxiety, and Stress Scale (DASS-21) was used to assess mental health symptoms, while socio-demographic and work-related information was collected through a questionnaire.
Based on the descriptive statistics of DASS-21 scores, the prevalence of mental health issues among the participants included high levels of depression (18%), anxiety (25%), …
Accelerated Tumor Progression After Covid-19 Infection In Patients With Glioblastoma: A Retrospective Case-Control Study, Timothy A Gregory, Stephanie R Knight, Ashley E Aaroe, Kaitlin N Highsmith, Zachary C Janatpour, Barbara J O'Brien, Nazanin K Majd, Monica E Loghin, Chirag B Patel, Shiao-Pei Weathers, Vinay K Puduvalli, Carlos Kamiya-Matsuoka
Accelerated Tumor Progression After Covid-19 Infection In Patients With Glioblastoma: A Retrospective Case-Control Study, Timothy A Gregory, Stephanie R Knight, Ashley E Aaroe, Kaitlin N Highsmith, Zachary C Janatpour, Barbara J O'Brien, Nazanin K Majd, Monica E Loghin, Chirag B Patel, Shiao-Pei Weathers, Vinay K Puduvalli, Carlos Kamiya-Matsuoka
Faculty, Staff and Student Publications
Background: We observed rapid tumor progression following COVID-19 infection among patients with glioblastoma and sought to systematically characterize their disease course in a retrospective case-control study.
Methods: Using an institutional database, we retrospectively identified a series of COVID-19-positive glioblastoma cases and matched them by age and sex 1:2 to glioblastoma controls who had a negative COVID-19 test during their disease course. Demographic and clinical data were analyzed. Hyperprogression was defined using modified response evaluation criteria in solid tumors criteria. Time to progression and overall survival were estimated using the Kaplan-Meier method.
Results: Thirty-two glioblastoma cases with positive COVID-19 testing were …
Challenges In Lncrna Biology: Views And Opinions, Donald A Adjeroh, Xiaobo Zhou, Alexandre Rossi Paschoal, Nadya Dimitrova, Ekaterina G Derevyanchuk, Tatiana P Shkurat, Jeffrey A Loeb, Ivan Martinez, Leonard Lipovich
Challenges In Lncrna Biology: Views And Opinions, Donald A Adjeroh, Xiaobo Zhou, Alexandre Rossi Paschoal, Nadya Dimitrova, Ekaterina G Derevyanchuk, Tatiana P Shkurat, Jeffrey A Loeb, Ivan Martinez, Leonard Lipovich
Faculty, Staff and Student Publications
This is a mini-review capturing the views and opinions of selected participants at the 2021 IEEE BIBM 3rd Annual LncRNA Workshop, held in Dubai, UAE. The views and opinions are expressed on five broad themes related to problems in lncRNA, namely, challenges in the computational analysis of lncRNAs, lncRNAs and cancer, lncRNAs in sports, lncRNAs and COVID-19, and lncRNAs in human brain activity.
Expanding A Behavioral View On Digital Health Access: Drivers And Strategies To Promote Equity, Maura M Kepper, Lauren A Fowler, Isabelle S Kusters, Jean W Davis, Manal Baqer, Sara Sagui-Henson, Yunyu Xiao, Adati Tarfa, Jean C Yi, Bryan Gibson, Kristin E Heron, Nicole M Alberts, Marissa Burgermaster, Veronica Ps Njie-Carr, Lisa M Klesges
Expanding A Behavioral View On Digital Health Access: Drivers And Strategies To Promote Equity, Maura M Kepper, Lauren A Fowler, Isabelle S Kusters, Jean W Davis, Manal Baqer, Sara Sagui-Henson, Yunyu Xiao, Adati Tarfa, Jean C Yi, Bryan Gibson, Kristin E Heron, Nicole M Alberts, Marissa Burgermaster, Veronica Ps Njie-Carr, Lisa M Klesges
Center for Medical Ethics and Health Policy Staff Publications
The potential and threat of digital tools to achieve health equity has been highlighted for over a decade, but the success of achieving equitable access to health technologies remains challenging. Our paper addresses renewed concerns regarding equity in digital health access that were deepened during the COVID-19 pandemic. Our viewpoint is that (1) digital health tools have the potential to improve health equity if equitable access is achieved, and (2) improving access and equity in digital health can be strengthened by considering behavioral science-based strategies embedded in all phases of tool development. Using behavioral, equity, and access frameworks allowed for …
A Community Health Worker Led Diabetes Self-Management Education Program: Reducing Patient And System Burden, Laura Porterfield, Xiaoying Yu, Victoria Warren, Michael E Bowen, Carolyn Smith-Morris, Elizabeth M Vaughan
A Community Health Worker Led Diabetes Self-Management Education Program: Reducing Patient And System Burden, Laura Porterfield, Xiaoying Yu, Victoria Warren, Michael E Bowen, Carolyn Smith-Morris, Elizabeth M Vaughan
Faculty, Staff and Students Publications
Aims: Conduct a secondary analysis of the TIME (Telehealth-supported, Integrated Community Health Workers (CHWs), Medication access, diabetes Education) made simple trial (SIMPLE) to evaluate healthcare utilization and explore variables that may have influenced HbA1c.
Methods: Participants (N = 134 [67/group]) were low-income, uninsured Hispanics with or at risk for type 2 diabetes mellitus. We included in-person and telehealth clinician visits, other visits, missed visits, orders placed, and guideline-adherence (e.g., vaccinations, quarterly HbA1c for uncontrolled diabetes). Using multivariable models, we explored for associations between HbA1c changes and these measures.
Results: The control arm had higher missed visits rates (intervention: 45 %; …
Pediatric Mental Health Emergency Department Visits From 2017 To 2022: A Multicenter Study, Jennifer A Hoffmann, Camille P Carter, Cody S Olsen, David Ashby, Kamali L Bouvay, Susan J Duffy, James M Chamberlain, Sofia S Chaudhary, Nicolaus W Glomb, Jacqueline Grupp-Phelan, Maya Haasz, Erin P O'Donnell, Mohsen Saidinejad, Bashar S Shihabuddin, Leah Tzimenatos, Neil G Uspal, Joseph J Zorc, Lawrence J Cook, Elizabeth R Alpern
Pediatric Mental Health Emergency Department Visits From 2017 To 2022: A Multicenter Study, Jennifer A Hoffmann, Camille P Carter, Cody S Olsen, David Ashby, Kamali L Bouvay, Susan J Duffy, James M Chamberlain, Sofia S Chaudhary, Nicolaus W Glomb, Jacqueline Grupp-Phelan, Maya Haasz, Erin P O'Donnell, Mohsen Saidinejad, Bashar S Shihabuddin, Leah Tzimenatos, Neil G Uspal, Joseph J Zorc, Lawrence J Cook, Elizabeth R Alpern
Faculty, Staff and Students Publications
Background: The COVID-19 pandemic adversely affected children's mental health (MH) and changed patterns of MH emergency department (ED) utilization. Our objective was to assess how pediatric MH ED visits during the COVID-19 pandemic differed from expected prepandemic trends.
Methods: We retrospectively studied MH ED visits by children 5 to < 18 years old at nine U.S. hospitals participating in the Pediatric Emergency Care Applied Research Network Registry from 2017 to 2022. We described visit length by time period: prepandemic (January 2017-February 2020), early pandemic (March 2020-December 2020), midpandemic (2021), and late pandemic (2022). We estimated expected visit rates from prepandemic data using multivariable Poisson regression models. We calculated rate ratios (RRs) of observed to expected visits per 30 days during each pandemic time period, overall and by sociodemographic and clinical characteristics.
Results: We identified 175,979 pediatric MH ED visits. Visit length exceeded 12 h for 7.3% prepandemic, 8.4% early pandemic, 15.0% midpandemic, and 19.2% late pandemic visits. During the early pandemic, observed visits per 30 days decreased relative to expected rates (RR 0.80, 95% confidence interval [CI] 0.78-0.84), were similar to expected …
Increasing Incidence Of Streptococcus Anginosus Group Intracranial Infections Associated With Sinusitis, Otitis Media, And Mastoiditis In Children, Elisabeth A Hoyer, Marritta Joseph, James Dunn, Howard L Weiner, Amy Dimachkieh, Anthony R Flores, Misu A Sanson, Hossaena Ayele, Blake M Hanson, Sheldon L Kaplan, Jesus G Vallejo, J Chase Mcneil
Increasing Incidence Of Streptococcus Anginosus Group Intracranial Infections Associated With Sinusitis, Otitis Media, And Mastoiditis In Children, Elisabeth A Hoyer, Marritta Joseph, James Dunn, Howard L Weiner, Amy Dimachkieh, Anthony R Flores, Misu A Sanson, Hossaena Ayele, Blake M Hanson, Sheldon L Kaplan, Jesus G Vallejo, J Chase Mcneil
Faculty, Staff and Student Publications
BACKGROUND: The Streptococcus anginosus group (SAG) pathogens have the potential to cause head and neck space infections, including intracranial abscesses. Several centers noted an increase in intracranial abscesses in children during the SARS-CoV-2 pandemic, prompting a Centers for Disease Control and Prevention health alert in May 2022. We examined the epidemiology of pediatric intracranial abscesses at a tertiary care center with a focus on SAG pre- and post-pandemic.
METHODS: Cases of intracranial abscesses of any microbiologic etiology admitted from January 2011 to December 2022 were identified using International Classification of Diseases 10 codes. Subjects were cross-referenced with culture results from …
Preeclampsia In The Context Of Covid-19: Mechanisms, Pathophysiology, And Clinical Outcomes, Guilherme M Nobrega, Brittany R Jones, Indira U Mysorekar, Maria Laura Costa
Preeclampsia In The Context Of Covid-19: Mechanisms, Pathophysiology, And Clinical Outcomes, Guilherme M Nobrega, Brittany R Jones, Indira U Mysorekar, Maria Laura Costa
Center on Aging Staff Publications
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to the global COVID-19 pandemic, significantly impacting the health of pregnant women. Obstetric populations, already vulnerable, face increased morbidity and mortality related to COVID-19, aggravated by preexisting comorbidities. Recent studies have shed light on the potential correlation between COVID-19 and preeclampsia (PE), a leading cause of maternal and perinatal morbidity worldwide, emphasizing the significance of exploring the relationship between these two conditions. Here, we review the pathophysiological similarities that PE shares with COVID-19, with a particular focus on severe COVID-19 cases and in PE-like syndrome cases related with …
Leveraging Machine Learning And Stochastic Programming To Address Vaccine Hesitancy In Public Health Resource Allocation, Hieu Trung Bui
Leveraging Machine Learning And Stochastic Programming To Address Vaccine Hesitancy In Public Health Resource Allocation, Hieu Trung Bui
Graduate Theses and Dissertations
Infectious disease outbreaks highlight the urgent need for effective strategies to distribute vaccines and allocate critical healthcare resources to contain the disease and reduce its negative impacts on the population. Managing these allocations is a significant challenge, especially in marginalized communities facing uncertainty in healthcare demand and logistical constraints. This dissertation addresses these challenges by investigating factors that influence dynamic changes in vaccine hesitancy (VH) and its implications for disease spread and healthcare resource demand. It develops optimization models for vaccine distribution and resource allocation under uncertainty, validated with data from the COVID-19 pandemic in the U.S. The first study …
Establishment Of A Novel Prairie Vole (Microtus Ochrogaster) Sars-Cov-2 Infection And Transmission Model, Stephanie Rebecca Kehl
Establishment Of A Novel Prairie Vole (Microtus Ochrogaster) Sars-Cov-2 Infection And Transmission Model, Stephanie Rebecca Kehl
Open Access Theses & Dissertations
Considering that the number of SARS-CoV-2 cases and deaths continues to increase three years after the onset of the pandemic, the need for animal models to study disease pathology and test antiviral effectiveness remains paramount. Prairie voles offer unique advantages as an infection model, such as mirroring human social behavior, including pair bonding and biparental offspring rearing, having inducible estrus and ovulation cycles, and not being overly domesticated. Based on the sequence homology of the vole ACE2 receptor to that of other species that are susceptible to SARS-CoV-2, such as the ferret and hamster, we hypothesized that the vole ACE2 …
The Correlation Of Age With Thrombocytes And D-Dimer Values In Covid-19 Patients At Hospital X In Jakarta, Indonesia, Nanik Prasetyoningsih, Ascobat Gani
The Correlation Of Age With Thrombocytes And D-Dimer Values In Covid-19 Patients At Hospital X In Jakarta, Indonesia, Nanik Prasetyoningsih, Ascobat Gani
Kesmas
Coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, spread globally, with research indicating that prognosis severity can be assessed by thrombocyte and D-dimer levels; while, patient age serves as a mortality predictor. This study aimed to analyze the relationship between age with thrombocytes and D-dimer in COVID-19 patients. This cross-sectional study used laboratory testing samples from 667 COVID-19 patients at Hospital X in Jakarta, Indonesia, collected from August 2020 until May 2021. The data was collected using cluster random sampling and analyzed using descriptive statistics and the Chi square test (95% CI). The results showed that age and thrombocytes positively …
A Mixed Methods Exploration Of Young Women's Agency And Mental Health During Covid-19 In Low-Income Communities In Mumbai, India, Marie A Brault, Melissa F Peskin, Anastasia N Jones, Amrita Saikia, Rinchen O Bhutia, Sai Sammitha Cheruvu, Vaishali M Jagtap, Rajendra Singh, Poornima Nair, Rajesh Vedanthan, Sten H Vermund, Shubhada Maitra
A Mixed Methods Exploration Of Young Women's Agency And Mental Health During Covid-19 In Low-Income Communities In Mumbai, India, Marie A Brault, Melissa F Peskin, Anastasia N Jones, Amrita Saikia, Rinchen O Bhutia, Sai Sammitha Cheruvu, Vaishali M Jagtap, Rajendra Singh, Poornima Nair, Rajesh Vedanthan, Sten H Vermund, Shubhada Maitra
Faculty, Staff and Student Publications
Introduction: Adolescent girls and young women (AGYW) in India face additional health inequities compared to their male peers, as gender norms constrain agency for prevention and self-care. The onset of the COVID-19 pandemic and associated lockdowns deepened health inequities and often worsened mental health, but the impacts on agency are unclear. This exploratory sequential mixed methods paper examined mental health and COVID-19 elements that exacerbated or mitigated adverse consequences for AGYW in low-income communities in Mumbai.
Methods: We conducted semi-structured interviews with AGYW (aged 15-25 years; N = 60) and adults (parents, healthcare providers, community-based organization representative; N = 30). …
Frailty Explains Variation In Emergency Department Use For Older Veterans During The Covid-19 Pandemic, Justine Seidenfeld, Karen M. Stechuchak, Valerie A. Smith, Catherine Stanwyck, Chelsea Perfect, Courtney Van Houtven, Susan Nicole Hastings
Frailty Explains Variation In Emergency Department Use For Older Veterans During The Covid-19 Pandemic, Justine Seidenfeld, Karen M. Stechuchak, Valerie A. Smith, Catherine Stanwyck, Chelsea Perfect, Courtney Van Houtven, Susan Nicole Hastings
Journal of Geriatric Emergency Medicine
Background: Older adults were critically vulnerable to disruptions in health care during the COVID-19 pandemic, but it is not known if changes in ED utilization varied based on patient characteristics. Using a cohort of older Veterans, we examined changes in ED visit rates based on four characteristics of interest: age, race, area deprivation index, and frailty
Methods: Participants were aged ≥65, with ≥2 visits in primary or geriatric clinics between 02/02/2018-05/07/2019. An adjusted negative binomial regression model was constructed for each characteristic. We report mean counts of all ED visits by quarter for subgroups separately, and report rate …
The Association Between Prolonged Sars-Cov-2 Symptoms And Work Outcomes, Arjun K Venkatesh, Huihui Yu, Caitlin Malicki, Michael Gottlieb, Joann G Elmore, Mandy J Hill, Ahamed H Idris, Juan Carlos C Montoy, Kelli N O'Laughlin, Kristin L. Rising, Kari A Stephens, Erica S Spatz, Robert A Weinstein
The Association Between Prolonged Sars-Cov-2 Symptoms And Work Outcomes, Arjun K Venkatesh, Huihui Yu, Caitlin Malicki, Michael Gottlieb, Joann G Elmore, Mandy J Hill, Ahamed H Idris, Juan Carlos C Montoy, Kelli N O'Laughlin, Kristin L. Rising, Kari A Stephens, Erica S Spatz, Robert A Weinstein
Department of Emergency Medicine Faculty Papers
While the early effects of the COVID-19 pandemic on the United States labor market are well-established, less is known about the long-term impact of SARS-CoV-2 infection and Long COVID on employment. To address this gap, we analyzed self-reported data from a prospective, national cohort study to estimate the effects of SARS-CoV-2 symptoms at three months post-infection on missed workdays and return to work. The analysis included 2,939 adults in the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE) study who tested positive for their initial SARS-CoV-2 infection at the time of enrollment, were employed before the pandemic, and completed …
Demystifying The Virtualization Process: A Call For Standard Reporting Of Virtual Modifications To Evidence-Based Psychotherapies, Using The Frame Model, Derrecka M Boykin, Tracey L Smith, Barbara Rakel, Merlyn Rodrigues, Jennie Embree, Ken Woods, Angelic D Chaison, Lilian Dindo
Demystifying The Virtualization Process: A Call For Standard Reporting Of Virtual Modifications To Evidence-Based Psychotherapies, Using The Frame Model, Derrecka M Boykin, Tracey L Smith, Barbara Rakel, Merlyn Rodrigues, Jennie Embree, Ken Woods, Angelic D Chaison, Lilian Dindo
Faculty, Staff and Students Publications
The sudden onset of the coronavirus disease led to a rapid expansion of video telehealth to deliver mental healthcare. Although video telehealth was not a new clinical practice, there was limited guidance on how best to modify evidence-based psychotherapies (EBPs) for virtual delivery (a process also referred to as virtualization). The virtualization process for EBPs remains unclear as newly emerging reports on this topic do not consistently report modification decisions. This commentary calls attention to the need to improve documentation practices to allow a greater understanding of modifications needed to maximize the positive effects of EBPs transported to a virtual …