Digital Commons Network^™

Predictors Of Psychological Strain In College Students In The Context Of The Covid-19 Pandemic, Randy M. Ludwig

Journal of Social, Behavioral, and Health Sciences

The coronavirus disease 2019 (COVID-19) pandemic exacerbated the traditional challenges of being a college student. This study examined the factors associated with the mental health difficulties many college students faced during the pandemic. Factor analysis was used to uncover a latent variable called psychological strain, which was composed of mental instability, mental health strain, sadness, anxiety, and unhappiness. An exploratory path model was created to determine which factors most closely related to psychological strain. Of the 14 factors considered, 11 were significant predictors. Overall, the most important risk factor was found to be social isolation (total effects = .437), while …

Connected But Disconnected: A Covid-19 Youth Participatory Action Research Study, Vianney Atugonza, Jodi Dworkin, Stacey S. Horn, Joanna A. Tzenis, Samantha Lebouef

Journal of Youth Development

In 2020, the COVID-19 pandemic forced most schools across the U.S. to close and transition to remote learning. Families were forced to transform their homes into classrooms while facing challenges to their health, finances, and social connections. To better understand how young people experienced these changes, a Youth Participatory Action Research (YPAR) project was employed to engage young people in naming, exploring, and sharing their experiences during this time. Nine high school youth leaders were trained as researchers to conduct interviews with their peers. These youth scholars were also trained on how to code, sort, and disseminate data and results. …

A Web-Based Machine Learning Application For Classifying Post-Covid Risk Among Middle-Aged Adults, Himasha Amarathunga, Dhishan Dhammearatchi, Nimesh Pollwaththage

Journal of Innovation in Science, Engineering and Technology

Post-COVID syndrome (Long-COVID) represents a significant public health challenge, yet accessible tools for individual risk assessment among middle-aged adults remain limited. This study describes the development and evaluation of a web-based machine learning application for the classification of post-COVID risk in adults aged 30–60 years. A publicly available secondary dataset comprising 9,637 patient records was used, of which 5,871 (61%) were classified as high-risk and 3,766 (39%) as standard recovery, reflecting an imbalanced class distribution. The web application incorporates key demographic and clinical features including age, sex, vaccination status and comorbidities to produce a binary risk classification (High/Low). Five machine …

Fuimos Olvidados Y Descuidados [Forgotten And Neglected]: Lessons Learned And Findings From On-Farm Covid-19 Education And Vaccine Clinics For Agricultural Workers And Their Multigenerational Families In Texas, Anabel Rodriguez, David I Douphrate, Ana L Pineda Reyes, Susana Zavala, Lus Chavez, Sofia Nicole Lopez, Andrea V Cabrera Cruz, Annie J Keeney, Nora Hernandez, Brenda Berumen-Flucker, Eva M Shipp, Matthew W Nonnenmann, Shannon P Guillot-Wright, Bethany Boggess Alcauter, G Lopez Ixta, Paula M Cuccaro, Higinio Fernandez-Sanchez, David Gimeno Ruiz De Porras

Faculty, Staff and Student Publications

Background: Despite being deemed essential non-healthcare workers, agricultural workers were excluded from COVID-19 vaccine prioritization in Texas. This professional practice report describes the multifaceted worker health and safety approaches to protecting agricultural workers and their families during the COVID-19 pandemic.

Methods: Between March 2020 and January 2025, several outreach, education, and training grants from various funding agencies were leveraged to deliver training, personal protective equipment, vaccines, and economic relief to agricultural workers in partnership with community-based organizations, industry, local public health departments, and academic institutions.

Findings: Timely funding efforts led to the distribution of 1,000 PPE kits, with more than …

Impact Of Covid-19 Pandemic On Mathematics Achievement And Problem-Solving Ability: Insights From Secondary Schools In India, Laishram Nirtish Singh, Anand Jyoti Sanasam, Jocyline Thokchom, Ningombam Cha Cogent, Laisom Sharmeswar Singh

Journal of Humanistic Mathematics

The COVID-19 pandemic disrupted students’ engagement with mathematics. This study aims to contribute to our understanding of the extent of this disrupting by examining differences in mathematics achievement and problem-solving ability between adjacent cohorts who learned Class 8 under different schooling conditions in India: Group A (pandemic-exposed Class 8 cohort) and Group B (post-reopening Class 8 cohort). Using a descriptive design in a natural setting, we selected a stratified sample of 1,200 students from Class 9 and Class 10 across 21 secondary schools in Manipur, India. The sample was stratified by gender, family type, school type, and locality to ensure …

Clinicopathologic Spectrum Of Renal Disease In Sars-Cov-2 Infection And Post-Covid-19 Vaccination, Naya Williams, Mohammed S. Razzaque

School of Medicine Publications

Both SARS-CoV-2 infection and COVID-19 vaccination have been associated with renal complications. In the context of SARS-CoV-2 infection, kidney injury is primarily attributed to a complex interplay of systemic immune dysregulation and vascular damage. Severe infection triggers a cytokine-mediated inflammatory response characterized by elevated levels of pro-inflammatory mediators, resulting in systemic hemodynamic instability, increased capillary permeability, and renal hypoperfusion, ultimately leading to acute tubular injury. In addition, virus-induced endothelial activation promotes a prothrombotic state, microvascular injury, and further impairment of renal perfusion. Collectively, these processes converge to produce acute kidney injury (AKI) and, in severe or prolonged cases, may contribute …

Healthcare Or Gold? Comparative Safe-Haven Dynamics During The Covid-19 Market Crisis, Stephen Omoya

Critical Letters in Economics & Finance

This paper examines whether the US healthcare sector serves as a reliable defensive equity investment during periods of severe macroeconomic stress. Grounded in the Flight-to-Safety market phenomenon. The study investigates how extreme market uncertainty prompts capital reallocation into safer assets. Using daily data from LSEG Workspace for the Vanguard Health Care ETF (VHT), Gold, and the S&P 500, the research analyses a 25-month window from March 31, 2020, to May 31, 2022, yielding 567 observations. The Capital Asset Pricing Model (CAPM) was implemented to measure short-term market risk (β), while the Engle-Granger methodology tested for a long-run relationship between VHT …

A Glimpse Into Classrooms: Teachers’ Experiences Pre- And Post-Covid, Sam Hilbert, Katherine Wheeler, Robin H. Lock, Janna Brendle, Kassi Gregory

Journal of Educational Research and Practice

The COVID-19 pandemic forced many schools to pause in-person learning. Prior research indicates that these closures affected overall mental health and student academic performance. Mental health concerns, particularly anxiety and depression, were exacerbated for many school-aged children during these closures. Research has linked disorders, such as anxiety and depression, with changes in behaviors. Academic gaps have also been linked with negatively displayed behaviors in school settings. COVID school closures resulted in a 25% increased global prevalence of anxiety and depression diagnoses and an estimated 1-year academic loss in student learning. Although both variables have been shown to contribute to changes …

Longitudinal Genomic Surveillance Of Sars-Cov-2 In A University Microcosm Reflects Global Evolutionary Trends, Sankar Prasad Chaki, Melissa M Kahl-Mcdonagh, Benjamin W Neuman, Loni A Taylor, Rebecca S B Fischer, Blake M Hanson, Marlisa S Hardy, Jo Ann Culpepper, Eric Boerwinkle, Kurt A Zuelke

Faculty, Staff and Student Publications

SARS-CoV-2 transmission has declined, yet ongoing viral evolution continues to pose public health challenges. This study conducted long-term (2020-2024) genomic surveillance within a large and globally diverse university community. Viral genomes obtained from clinical (n = 1,786) and surveillance (n = 888) testing samples were classified under clade, lineage, and variant systems, and compared with global genomic data sets. Local patterns broadly paralleled global evolutionary trends, including the phased emergence of major variants, episodic introductions of new lineages, and shifts in dominant clades. Lineage diversity peaked during fall semesters and was highest among undergraduate-aged individuals, with similar distributions …

Rapid Recovery Of Peripheral Oxygen Saturation In Hypoxic Covid-19 Patients With Ivermectin/Doxycycline/Zinc Multidrug Therapy, Sabine Hazan, Adriana C. Vidal, Eleftherios Gkioulekas, Anoja W. Gunaratne, Sibaish Dolai, Robert L. Clancy, Peter A. Mccullough, Thomas J. Borody

School of Mathematical & Statistical Sciences Faculty Publications

Several combination therapies for the early outpatient treatment of COVID-19 were proposed by independent research groups at the onset of the pandemic during 2020 and 2021. In this observational study, we report on the outcomes of an off-label triple combination therapy, consisting of ivermectin, doxycycline, and zinc, with adjunct vitamin C and D3 supplementation, which was used on high-risk COVID-19 patients. These patients refused an initial recommendation to seek inpatient care, despite a high-risk presentation compounded with one or more comorbidities and/or severe hypoxia. Telemedicine was used to administer personalized treatment to patients at home, who did not have access …

Back To Intent: Revamping California’S Flagship Environmental Legislation And Tackling The Rise Of The “Super-Commuter”, Jordan Q. Davis

San Diego Journal of Climate & Energy Law

The passage of the California Environmental Quality Act (CEQA) in 1970 has long been considered a watershed moment in the evolution of government participation in environmental issues. In the years since, CEQA has played a pivotal role in protecting Californians’ access to the beautiful nature offered by the Golden State. However, the very regulation that has been repeatedly relied upon to breathe clean air and drink clean water may very well be an instrument upon which Californians could return to smog-ridden skies. In this regard, CEQA’s biggest vulnerability may come from a most unexpected place: its strength.

The tools by …

Screen-Based Simulation Assessment For Emergency Medicine Learners: A Rapid Review, Patrick Zeniecki, Rebecca Kamens, Jared Kilpatrick, Dimitrios Papanagnou, Xiao C. Zhang

Department of Emergency Medicine Faculty Papers

BACKGROUND: Simulation has played a vital role in training medical professionals. The COVID-19 Pandemic has highlighted the need for physically distant educational assessment methods. Screen-based simulation (SBS) demonstrates one alternative to traditional in-person simulation methods to assess learners clinical reasoning and communication skills. This study aims to compare in-person simulation to SBS as assessment methods in Emergency Medicine (EM).

METHODS: A rapid review literature search methodology of an electronic database (PubMed) was performed in February 2022 with search terms such as "Computer Simulation," "Patient Simulation," "Simulation Training," "Education, Distance," "Virtual OSCE," "Academic Performance," or "Emergency Medicine." Reference lists of relevant …

Socioeconomic Inequalities In Health-Related Quality Of Life During The Covid-19 Pandemic: A Six-Country Comparison Using The Eq-5d-5 L, Joëlle Eijkens, Joshua M. Bonsel, You-Shan Feng, M. F. Bas Janssen, Erica I. Lubetkin, Juanita A. Haagsma

Publications and Research

Purpose

Despite the growing attention to health inequalities, there is no global consensus on how to measure socio-economic status. This study examined inequalities in health-related quality of life (HRQoL) during the early phase of the COVID-19 pandemic across six countries—China, Italy, the Netherlands, Sweden, the United Kingdom (UK), and the United States (US)—using three SES indicators: education level, income, and work status.

Methods

Between April and June 2020, individuals aged 18–75 years old completed a web-based survey. HRQoL was measured using the EQ-5D-5L Level Sum Score (LSS), where higher scores indicate poorer health. Country-specific differences in LSS across SES groups …

Chronic Conditions And Mortality In Medicare Beneficiaries Before And After The Covid-19 Pandemic, R J Waken, Fengxian Wang, Jose F Figueroa, Rishi K Wadhera, Khavya Avula, E John Orav, Anne Mobley Butler, Karen E Joynt Maddox

2020-Current year OA Pubs

IMPORTANCE: There were well-documented changes in health care use during the COVID-19 pandemic. Little is known about whether there were any associated decreases in claims-based comorbidity ascertainment that might have relevance to health services and policy research.

OBJECTIVE: To quantify differences in claims-based comorbidity assessment in Medicare beneficiaries pre- vs post-COVID-19.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study analyzed data from the 30 Chronic Conditions Warehouse 1- or 2-year lookback claims algorithms to ascertain each comorbidity with exact date ranges for all fee-for-service (FFS) and Medicare Advantage (MA) beneficiaries. Data were analyzed from April 2025 to April 2026.

EXPOSURES: The …

Adoption And Diffusion Of At-Home Medical Tests, Jerome Christia

Atlantic Marketing Association Proceedings

No abstract provided.

A Qualitative Study Of Business Leaders – Comparing Uncertainty Differences & Similarities During Covid Vs. 2008 - 2009, Ryan Matthews

Atlantic Marketing Association Proceedings

No abstract provided.

Comparison Of Ecg Features, Cardiac Biomarkers, And Clinical Outcomes In Three Waves Of Hospitalized Covid-19 Pneumonia Patients With Cardiovascular Events, Yuchen Han, Jahnavi Sunkara, Tshura S Ali, Harideep Samanapally, Vidyulata Salunkhe, Fnu Deepti, Emma C. Huang, Justin J. Huang, Maiying Kong, Jiapeng Huang

The University of Louisville Journal of Respiratory Infections

Background

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a rapidly evolving virus that can severely impact the cardiovascular system. With new variants, it is important to characterize wave-specific (defined by dominant circulating variants) clinical changes.

Methods

A multi-center retrospective cohort study of patients hospitalized with SARS-CoV-2 community acquired pneumonia at eight adult acute-care hospitals in the city of Louisville, KY was conducted. Patients hospitalized with Coronavirus Disease 2019 (COVID-19) community acquired pneumonia who experienced a cardiovascular event between March 2020 and July 2022 were included in this analysis. Variant assignment was based on temporal prevalence rather than genomic confirmation, and …

International Spillover: How External, Global Events Such As Brexit And Covid-19 Have Impacted Housing Prices Within The Republic Of Ireland, Allie Riggs

Undergraduate Honors Thesis Collection

The housing market in Ireland has experienced such a great crisis in recent history that over a third of residents have considered moving to a more affordable country (Hogg, 2024). While a number of both causes and potential solutions have been analyzed in regard to this national crisis, I hypothesize that there has been a greater shock from external, global events in the COVID-19 pandemic and Brexit. In performing a regression on secondary data while controlling for macroeconomic factors that impact the housing market, I have identified a positive, significant association between these two exogenous shocks and their impact on …

Examining Nurse Burnout During The Covid-19 Pandemic: Causes And Mitigation Strategies, Melanie Sena

Honors Projects

Nurse burnout is a multidimensional occupational syndrome that predates the COVID-19 pandemic, yet the pandemic served as a catalyst that intensified its scope and severity in ways that the healthcare system was profoundly ill-equipped to manage. Characterized by emotional exhaustion, depersonalization, and a diminished sense of personal accomplishment, burnout among nurses accelerated dramatically between 2020 and 2022 as clinical workloads surged, personal protective equipment remained scarce, and moral distress became a near-universal experience across care settings. This review examines the primary systemic and individual contributors to nurse burnout during COVID-19, explores the consequences of burnout for both nurses and patients, …

Testimonios De Una Estudiante De Doctorado: Regaining Joy In Graduate School Through Research-Practice Partnerships, Sophia Piral Lee

The Qualitative Report

Through an epistolary critical autoethnography and Latina and Chicana feminist framework, I explore the question of how international graduate students of color can overcome cultural, linguistic, ethnoracial, and social class isolation on predominantly white campuses and in college towns. By writing a letter to my mother (one of my methods for survival in academia), I share my challenges as a Guatemalan, first-time mom, first-generation college student, international student, and non-English native speaker in graduate school during and after the COVID-19 pandemic. At the same time, this writing helps me recognize how I overcame my isolation and regained my joy and …

Challenges In The Ethical Review Process Of Covid-19 Related Research At Hrec-Tumed, Thailand, Wilaiwan Chimkhong, Thana Khawcharoenporn, Pacharapan Surapolchai

Asian Medical Journal and Alternative Medicine

Objective: To explore the challenges encountered in the ethical review process and timeline of COVID-19 related research at the Human Research Ethics Committee of Thammasat University (Medicine) (HREC-TUMED), Thailand, focusing on submission characteristics, review outcomes, and committee adaptations.

Materials and Methods: This retrospective descriptive study analyzed COVID-19 research protocols submitted to HREC-TUMED between June 2020 and July 2022. Protocols were evaluated for research types, investigator affiliations, funding sources, review types, and timeline metrics, using descriptive statistics.

Results: A total of 89 COVID-19 related research protocols were submitted to HREC-TUMED, with the majority originating from faculty investigators (64%). Most protocols underwent …

Bridging The Gap: Perception And Certainty, Elizabeth C. Alexander, Monisha Gupta, Paige Leonard

Atlantic Marketing Association Proceedings

No abstract provided.

Strategic Resource Management In Pandemics: Integrating Capacity Planning With Non-Pharmaceutical Interventions For Covid-19, Ozlem Cosgun, Eyyub Kibis, Ali Dag, Burak Cankaya

Department of Information Management and Business Analytics Faculty Scholarship and Creative Works

The COVID-19 pandemic underscored the urgent need for integrated healthcare resource planning to manage patient surges and reduce mortality. This study presents a novel optimization-based framework that jointly considers healthcare capacity planning and non-pharmaceutical interventions (NPIs), including mask mandates, social distancing, and quarantining. The framework extends traditional compartmental models by distinguishing patient categories—such as hospitalized non-ventilator patients, ventilated patients, and ICU admissions—within a mixed-integer programming (MIP) structure that remains computationally tractable. Applied to the COVID-19 outbreak in New York City, the model optimizes the allocation of hospital beds and ventilators while minimizing deaths. Results show that combining high-effectiveness NPIs with …

Partisan Differences In Risk-Taking In A Simulated Pandemic, Jan K. Woike, Sebastian Hafenbrädl, Patricia Kanngiesser, Ralph Hertwig

School of Psychology

Responses to COVID-19 in the United States were split along partisan political lines throughout the pandemic. People on the political left tended to take the medical threat more seriously and were more likely to adopt preventive health behaviors than those on the political right, resulting in clear differences in state-level policies and health consequences. Here, we examine the origins of these differences, investigating whether they are based on interindividual differences or in party dynamics. Two groups of participants (N=819), who had voted either for Donald Trump or Hillary Clinton in 2016, played the Transmission Game. Players made repeated decisions in …

Acute Myocardial Infarction In Medicare Beneficiaries During And After The Covid-19 Pandemic, Jonah M Graves, R J Waken, Fengxian Wang, Rishi K Wadhera, Jose F Figueroa, E John Orav, Osvaldo J Laurido-Soto, Karen E Joynt Maddox

2020-Current year OA Pubs

IMPORTANCE: During early months of the COVID-19 pandemic, presentations for acute myocardial infarction (AMI) declined significantly, and outcomes worsened. However, the full extent and long-term sequelae of changes in AMI epidemiology during the pandemic remain uncertain, as does whether these patterns differed by rurality.

OBJECTIVE: To describe the epidemiology of AMI-related hospitalizations, interventions, and outcomes among Medicare beneficiaries throughout the COVID-19 pandemic, focusing on differences in urban and rural populations.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included all Medicare fee-for-service beneficiaries with AMI between January 1, 2018, and December 31, 2023, in the analysis. Data were analyzed from …

Clinical Features, Laboratory Characteristics, And Outcomes Of Covid-19 Patients In A Tertiary Care Reference Hospital In Panama City, Panama. A Retrospective Observational Study, Santiago E. Hernandez Bojorge

USF Tampa Graduate Theses and Dissertations

Latin America experienced some of the world’s highest COVID-19 mortality rates, yet data on in-hospital outcomes and their social and geographic determinants remain limited. This dissertation investigated multilevel baseline factors associated with in-hospital mortality among adults with COVID-19 at Panama’s largest public tertiary hospital (Hospital Santo Tomás), integrating survival, mediation, and spatial-temporal modeling within a causal-inference framework.

A retrospective cohort of 1,526 RT-PCR–confirmed COVID-19 hospitalizations (May 2020–November 2021) was analyzed using multivariable Cox proportional-hazards, Fine–Gray competing-risk, mediation, and Bayesian spatial models. Directed acyclic graphs (DAGs) pre-specified causal relationships and minimally sufficient adjustment sets. DAG-guided models quantified total effects without conditioning …

Examining The Effect Of Household Socioeconomic Status And Maternal Characteristics On Child Developmental Delay In The United States, Samuel Ilori

USF Tampa Graduate Theses and Dissertations

Child developmental delay remains a pressing public health issue with lifelong implications. This study examines the association between household socioeconomic status, maternal characteristics, and child developmental delay using data from the 2023 National Survey of Children's Health (N = 35,399 female respondents). Bivariate analyses using Chi-square tests and binary logistic regression with sequential modeling were conducted. Results revealed that economic hardship, employment status, maternal mental health, maternal physical health, marital status, and race were significantly associated with child developmental delay (p<0.001). Educational level and poverty level showed no significant associations. Among mothers reporting poor mental health, 90.0% had a child with a delay, compared to 6.6% among those with good mental health. Every mother reporting poor physical health had a child with a delay, while virtually none with good or better physical health did. In the fully adjusted regression model, maternal mental and physical health remained the most powerful predictors, while economic hardship and employment status became non-significant once health was introduced, suggesting mediation. Maternal mental and physical health are the factors most strongly correlated with child developmental delay. Economic hardship matters primarily because it undermines maternal well-being. The COVID-19 pandemic likely intensified these dynamics by disrupting healthcare access and increasing economic instability. Supporting maternal health must be recognized as a fundamental strategy for promoting child development. Universal screening for maternal depression and physical health problems, integrated into pediatric and obstetric care, can identify at-risk mothers early. Policies that reduce economic hardship alleviate the chronic stress that undermines maternal health. Children thrive when their mothers are healthy.

Computational Discovery Of Sars-Cov-2 Viral Entry Inhibitory Peptides From Androctonus Mauretanicus Scorpion Venom: Molecular Docking And Molecular Dynamics Simulations Targeting The Spike Protein, Reda Chahir, Salaheddine Redouane, Jacob Galan, Hicham Hboub, Lahoussaine Aserrar, Salma Chakir, Ahmed Salim Lahlou, Hinde Aassila, Rachid El Fatimy, Naoual Oukkache

School of Medicine Publications

Background and Objective: 

While vaccination remains central to controlling the COVID-19 pandemic, the emergence of SARS-CoV-2 variants with partial resistance to immune responses has highlighted the need for complementary therapeutic strategies. Among these, antiviral agents that inhibit viral entry mechanisms are of particular interest. Animal venoms, especially scorpion venoms, are a rich source of bioactive peptides with potential antiviral properties. This study aimed to evaluate peptides derived from the Moroccan scorpion Androctonus mauretanicus as inhibitors of SARS-CoV-2 spike glycoprotein, which mediates virus entry into host cells via ACE2 receptor binding.

Material and Methodology: 

Six peptides from the venom of the …

Muscular Fitness Levels Of U.S. Children And Adolescents, Daniel J. Mcdonough, Yong Gao, Lynda B. Ransdell, Haichun Sun

International Journal of Physical Activity and Health

Purpose: To describe muscular fitness (MF) levels and percentile benchmarks among U.S. children and adolescents aged 6–15 years old across sociodemographic, physiological, and behavioral subgroups. Methods: Data were from the 2012 NHANES National Youth Fitness Survey (NNYFS). Four strength tests consisting of the plank, knee extension, modified pull-up, and handgrip, were analyzed by age, sex, race/ethnicity, income, BMI category, cardiorespiratory fitness (CRF), and physical activity (PA) among 1,234 participants (51% male) using SAS SURVEY procedures. Results: Mean ± SEM scores were 69.6 ± 1.8 s (plank), 56.6 ± 4.2 lb (left) and 59.2 ± 4.3 lb (right) knee extension, 5.5 …

Sectoral Shockwaves: Examining Bursa Malaysia's Sector Indices Amid The Covid-19 Pandemic, Alyssa April Dellow, Hafizah Bahaludin

International Journal of Management, Finance and Accounting

The Coronavirus disease 2019 (COVID-19) outbreak is becoming a widespread concern, as it is causing a decline in economies and negatively impacting stock markets worldwide. As the Malaysian government implements the Movement Control Order (MCO) to curb the spread of the deadly virus, the Malaysian stock market is rapidly impacted, becoming volatile and unpredictable throughout the pandemic phase. Thus, this study aims to analyse the structural correlation patterns of the Bursa Malaysia Sectoral Index Series using the threshold network approach. The data utilised in this study are the closing prices of all 13 sectoral indexes, spanning from January 1, 2019, …