Digital Commons Network^™

A Basic Guide For Empirical Environmental Social Science, Michael Cox

Dartmouth Scholarship

In this paper, I address a gap in the literature on environmental social science by providing a basic rubric for the conduct of empirical research in this interdisciplinary field. Current literature displays a healthy diversity of methods and techniques, but this has also been accompanied by a lack of consistency in the way in which research in this area is done. In part this can be seen as resulting from a lack in supporting texts that would provide a basis for this consistency. Although relevant methods texts do exist, these are not written with this type of research explicitly in …

Developing A Gene Editing System To Study Haplodiploidy In The Jewel Wasp, Nasonia Vitripennis, Emily A. Muller

Scripps Senior Theses

Hymenopteran insects, which include all ants, bees and wasps, reproduce through a poorly understood form of reproduction known as haplodiploidy. A promising experimental system for understanding this developmental process is the jewel wasp, Nasonia vitripennis. A critical aspect of using Nasonia as a model is establishing an effective means for editing specific genes of interest so that their functions can be studied through genetic means. For my thesis research, I performed a pilot study of the gene editing method known as CRISPR in Nasonia. I targeted the single heterochromatin protein 1 (HP1) gene present in the Nasonia genome …

Morphometric Analysis Of Left & Right Tonsils In Adult Symptomatic Type 1 Chiari Patients And Healthy Controls, Louis J. Konstan

Williams Honors College, Honors Research Projects

Historically, CMI has been radiographically defined by cerebellar tonsillar descent below the foramen magnum (FM) more than 5 mm (2). This measurement is typically made with a single sagittal plane T1-or T2-weighted MR image. Studies have obtained additional morphometric measurements to help diagnose CMI, and establish normal values (3,4). These studies were somewhat These studies were somewhat successful in differentiating CMI patients from healthy subjects. However, results from these studies have shown that the standard TD measurement does not necessarily correlate with neurological symptom severity as patients with CMI-like symptoms have been found with a TD of less than 5 …

Electrical Resistivity Imaging For Long-Term Autonomous Monitoring Of Hydrocarbon Degradation: Lessons From The Deepwater Horizon Oil Spill, Jeffrey W. Heenan, Lee D. Slater, Dimitrios Ntarlagiannis, Estella A. Atekwana, Babu Z. Fathepure, Sonal Dalvi, Cameron Ross, D. Dale Werkema, Eliot A. Atekwana

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Conceptual models for the geophysical responses associated with hydrocarbon degradation suggest that the long-term evolution of an oil plume will result in a more conductive anomaly than the initial contamination. In response to the Deepwater Horizon (DH) oil spill into the Gulf of Mexico in 2010, an autonomous resistivity monitoring system was deployed on Grand Terre, Louisiana, in an attempt to monitor natural degradation processes in hydrocarbon-impacted beach sediments of this island. A 48-electrode surface array with a 0.5-m spacing was installed to obtain twice-daily images of the resistivity structure of the shallow subsurface impacted by oil. Over the course …

Evaluation Of The Signature Molecular Descriptor With Blosum62 And An All-Atom Description For Use In Sequence Alignment Of Proteins, Lindsay M. Aichinger

Williams Honors College, Honors Research Projects

This Honors Project focused on a few aspects of this topic. The second is comparing the molecular signature kernels to three of the BLOSUM matrices (30, 62, and 90) to test the accuracy of the mathematical model. The kernel matrix was manipulated in order to improve the relationship by focusing on side groups and also by changing how the structure was represented in the matrix by increasing the initial height distance from the central atom (Height 1 and Height 2 included).

There were multiple design constraints for this project. The first was the comparison with the BLOSUM matrices (30, 62, …

Human Anatomy And Physiology Preparatory Course (1st Edition), Carlos Liachovitzky

Open Educational Resources

The overall purpose of this preparatory course textbook is to help students familiarize with some terms and some basic concepts they will find later in the Human Anatomy and Physiology I course.

The organization and functioning of the human organism generally is discussed in terms of different levels of increasing complexity, from the smallest building blocks to the entire body. This Anatomy and Physiology preparatory course covers the foundations on the chemical level, and a basic introduction to cellular level, organ level, and organ system levels. There is also an introduction to homeostasis at the beginning.

Induction Of Larval Settlement In The Reef Coral Porites Astreoides By A Cultivated Marine Roseobacter Strain, Koty H. Sharp

Arts & Sciences Faculty Publications

Successful larval settlement and recruitment by corals is critical for the survival of coral reef ecosystems. Several closely related strains of γ-proteobacteria have been identified as cues for coral larval settlement, but the inductive properties of other bacterial taxa naturally occurring in reef ecosystems have not yet been explored. In this study, we assayed bacterial strains representing taxonomic groups consistently detected in corals for their ability to influence larval settlement in the coral Porites astreoides. We identified one α-proteobacterial strain, Roseivivax sp. 46E8, which significantly increased larval settlement in P. astreoides. Logarithmic growth phase (log phase) cell cultures of Roseivivax …

Is Polyvinylidene Diflouride (Pvdf) Film Biocompatible In The Murine Cochlea?, Robert Maxwell Jaggers

Browse all Theses and Dissertations

Polyvinylidene fluoride (PVDF) film, a biomaterial that is an integral part of a Totally Implantable Sustainable Hearing Aide (TISHA) device, was examined to determine its biocompatibility within the murine cochlea. The biofilm was implanted in the ear using a round window cochleostomy in 7-9 week old male C57BL/6 mice. Three test groups containing seven mice each were implanted with PVDF film. Each mouse received a sham surgery on the non-implanted cochlea. Three test groups were examined at 48 hours, 3 weeks, and 3 months. At the end of this time the mouse was euthanized, the tissue containing the cochlea was …

Tp53 And Hras Influence On Hpv16 E7 Expression In Hpv16-Transformed Human Keratinocytes, Nella Christie Delva

Theses and Dissertations

Head and Neck Squamous Carcinoma (HNSCC) is one of the most common cancers worldwide. HNSCC affects regions of the upper aerodigestive tract such as the lip, tongue, nasopharynx, oropharynx, larynx, and hypopharynx. About 25% of all HNSCC cases and up to 65% of Oropharyngeal Carcinoma (OPC) cases are positive for HPV DNA. African American patients, especially males, present primarily with HPV-negative HNSCC. HNSCC’s that are HPV-positive tend to be HPV-active at initial presentation: these cancers contain HPV DNA and express HPV RNA. However, recurring HPV-positive cancers of the head and neck are more often inactive: these tumors contain HPV DNA, …

Parental Experience And Its Effects On Reproductive Success In Common Loons, Brandon S. Braden Ms

All Student Scholarship

Common Loons (Gavia immer) are a highly territorial , long-lived species of waterbird that breed throughout the northern tier of North America. Loons form pair bonds seasonally, on their breeding territories, but overwinter separately. Much is known about environmental effects on loon reproductive success but little is known about how parental experience affects reproductive outcomes. I investigated the effects that individual experience and breeding pair length have on the reproductive success of Common Loons. The data I used were a compilation of individual territory occupancy and breeding records that were obtained by the Biodiversity Research Institute in Gorham, Maine from …

Students' Attitudes Towards Socially--But Not Scientifically--Controversial Subjects: Evaluating Ways In Which These Attitudes May Be Shifted, Benjamin Elijah Carter

Dissertations - ALL

Chapter1: Numerous anti-science bills introduced into state legislatures reference the "strengths and weaknesses" of scientific subjects, but the subjects they target, most commonly evolution and global climate change, are not topics of contention within the scientific community. This brief work provides a researched rebuttal to the notion that evolution and climate change have strengths and weaknesses of the form implied by anti-science legislation while providing examples of actual scientific disagreement about these subjects. The disagreement is not, of course, about whether or not evolution or climate change are factual occurrences, but rather over ideas such as the finer points of …

Effects Of Traditional Versus Electronic Note Taking In A High School Biology Classroom, Chelsea Ann Duhon

LSU Master's Theses

This study investigated the effect of traditional and electronic note taking on student achievement and engagement in a Louisiana high school biology classroom. Over a 20-week period, traditional students (n= 58) took notes using pencil and paper and electronic note takers (n=46) used their laptop computers. Each group of students was given identical pre and posttests covering three units and a practice End of Course exam. Normalized learning gains were compared for each unit and suggest there is no significant difference in academic achievement between the traditional note takers and the electronic note takers. An attitudinal survey was also administered …

A Quantum Theory Of Consciousness May Require A Paradigm Shift In Biology, Maurice Goodman

Articles

It is often assumed that the known physical laws form a closed system and are complete. It is also assumed that biological theories require no additional principles that are fundamental other than those we already know. Assumptions such as these are acting as a barrier to progress in biological theories and an understanding of consciousness. This paper examines the unexplained inconsistencies among fundamental particles and forces and the fundamental gaps in our knowledge of biology and the cell in particular that may impact on such progress. Also, the laws of quantum mechanics are examined and found to be grossly incomplete. …

Modeling Atp-Binding Cassette G2 (Abcg2) Substrate Specificity, Raghav D. Acharya, Aurijit Sarkar, Glen E. Kellogg

Undergraduate Research Posters

How well can we predict efflux by ATP-binding cassette G2?

It is estimated that there will be about 1.6 million new cases of cancer and half a million cancer deaths in the US during 2015.ATP-binding cassette (ABC) efflux transporters such as ABCG2 are overexpressed in chemotherapy-resistant cancer cells. Anticancer drugs are prone to efflux by these transporters. Being able to identify drugs that are effluxed is of great interest in drug discovery.The current arsenal of methods used to detect efflux are not easily adaptable to high throughput formats and are limited in scope, making experimental analysis an expensive prospect. Hence, …

Combination Of Music And Aromatherapy To Improve The Efficiency Of Motor Functions And Speech In Patients Paralyzed From Stroke., Mounica Bevara

Undergraduate Research Posters

With the rapid development of medical technology, millions of dollars are being spent on discovering innovative methods of treating fatal diseases such as stroke that may also result in temporary paralysis. Physiotherapy treatments aimed at restoring brain function in patients paralyzed following a stroke is subjective to the patient and does not guarantee complete rehabilitation. While many practitioners have attempted to employ complementary and alternative methods of treatment such as massage therapy, acupuncture therapy, siddha, and marma therapy, none of them proved to be equally as effective as physiotherapy. However, prior studies support the notion that aromatherapy used in combination …

Disproportion Of Women In General Surgery And Obstetrics-Gynecology Professions, Nidhi H. Patel

Undergraduate Research Posters

An increasingly number of women have been enrolling in U.S. medical schools recently and the field of obstetrics-gynecology has become predominantly female, but the profession of general surgery still remains largely unequal between the two genders. There is an observable pattern of gender inequality in both of these specialties, which is a result of several different factors which affect all women regardless of their profession. I studied how the stark difference in the percentages of female surgeons versus the percentages of female obstetricians-gynecologists compared to men has been created due to the prescribed gender roles of women in society. I …

Using The Past To Restore The Future: Quantifying Historical Vegetation To Assist In Tidal Freshwater Wetland Restoration, Christopher D. Gatens

Undergraduate Research Posters

Wetlands have been providing humans with critical natural ecosystem services throughout our time on Earth. Nevertheless, these invaluable ecosystems have been habitually altered as a cost of human progression. Two of the most common alterations to wetlands are damming and filling. Both occurred along Kimages Creek in Charles City County, VA during the 19^th and 20^th centuries. In 2010 the Lake Charles dam was partially removed, restoring the creek’s tidal communication with the James River. Upon the recession of the body of water, numerous woody stumps were revealed. We studied these stump remnants in an attempt to assess …

Spatial Analysis Of Nest Productivity And Predation In Prothonotary Warblers, Miranda Foster, Lesley P. Bulluck

Undergraduate Research Posters

Generally, statistics are based off the assumption that observations are independent from each other in space. In larger ecological systems however, there can be spatial autocorrelation whereby data collected in nearby areas are not independent of one another which violates the assumption of most statistical tests. It is therefore becoming commonplace for ecological studies to study spatial autocorrelation to both eliminate error (accounting for a nuisance variable that could give false positives) and to better understand the spatial structure of their system of interest. Indeed, the mechanisms that lead to spatial autocorrelation are often associated with behaviors and/or intrinsic characteristics …

Smoking Patterns Among Vcu Students, Jasmine Saini

Undergraduate Research Posters

For some individuals, college can be a high risk time for the development of problems associated with alcohol use and other substances. The purpose of this study is to examine these initiation and use patterns as they relate to nicotine use among college students 18 years of age and older enrolled in Spit for Science: The VCU Student Survey. The Spit for Science research project evaluates how genetic and environmental factors contribute to substance use and emotional health among college students at VCU. This study uses data from the Spit for Science 2011 cohort (n=2007) to investigate smoking patterns among …

Bio-Enhanced Constructivism: Moral Facts For The Naturalistic But Morally Serious Philosopher, Jason Gardner

Arts & Sciences Graduate Student Theses and Dissertations

ABSTRACTBio-Enhanced Constructivism: Moral Facts for the Naturalistic but Morally Serious PhilosopherbyJason GardnerDoctor of Philosophy in PhilosophyWashington University in St. Louis, 2014Professor Eric Brown, ChairThere is a tension between being both morally and naturalistically serious because it is doubtful that features philosophers have ascribed to moral facts in order to explain why we should take them seriously can be given a naturalistic accounting. Yet even serious naturalists who think the tension is real and troubling persist in trying to be serious moralists. I do not think they can do so on their own terms. Thus the purpose of this dissertation: to …

Characterizing The Evolutionary Path(S) To Early Homo, Lauren Schroeder, Charles C. Roseman, James M. Cheverud, Rebecca R. Ackermann

Biology: Faculty Publications and Other Works

Numerous studies suggest that the transition from Australopithecus to Homo was characterized by evolutionary innovation, resulting in the emergence and coexistence of a diversity of forms. However, the evolutionary processes necessary to drive such a transition have not been examined. Here, we apply statistical tests developed from quantitative evolutionary theory to assess whether morphological differences among late australopith and early Homo species in Africa have been shaped by natural selection. Where selection is demonstrated, we identify aspects of morphology that were most likely under selective pressure, and determine the nature (type, rate) of that selection. Results demonstrate that selection must …

An Activity Aimed At Improving Student Explanations Of Biological Mechanisms, Caleb M. Trujillo, Trevor R. Anderson, Nancy J. Pelaez

PIBERG Instructional Innovation Materials

This document is intended for use by instructors and their students. The activity contains steps to introduce students to the MACH model involving analyzing and discussing explanations about biological mechanisms. Initially, students read modified articles about biological mechanisms during class, although instructors may prefer to assign readings outside of class before the activity. During the activity, students are required to analyze the readings for evidence of research methods, analogies, context, and mechanisms. In so doing, students learn how to integrate the information pertaining to each of the MACH model components into a coherent explanation about their biological mechanism. After performing …

A Tetrahedral Version Of The Mach Model For Explaining Biological Mechanisms, Caleb M. Trujillo, Trevor R. Anderson, Nancy J. Pelaez

PIBERG Instructional Innovation Materials

This document is intended for both instructors and students. Modified from the original MACH model this version, once cut and folded, creates a tetrahedral model that can conveniently be used as a teaching and learning tool to inform and guide students on how to write expert quality explanations of biological mechanisms. Each vertex of the tetrahedron represents a component of the model namely, Methods, Analogy, Context, and How. For a coherent and complete explanation about molecular mechanisms, it is important to integrate information pertaining to all four components of the model. The tetrahedral MACH model has been tested in both …

Validating The Use Of Fluorescent Proteins As Molecular Probes In Vivo And In Vitro, Laura Elizabeth Dougherty

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Fluorescent proteins are widely used in cell biology as molecular probes to observe a protein of interests location and movement and also to study protein-protein interactions. The study of protein-protein interactions is observed using a technique called fluorescent resonance energy transfer (FRET). FRET is used as a way to approximate distances between proteins in vivo and requires at least two fluorescent proteins in order to utilize the process. The most popular pairing is enhanced cyan and yellow fluorescent (eCFP/eYFP) proteins. To view protein localization, fluorescent proteins are attached to the protein of interest. PSD-95, a scaffolding protein in the post …

Online Versus Face-To-Face Biology: A Comparison Of Student Transactional Distance, Approach To Learning, And Knowledge Outcomes, Mary Erin Riggins

Dissertations

Community colleges are among many other institutions increasing course offerings online, but there is still some concern about the quality of online learning. Educator concerns, a lack of empirical evidence on biology courses offered online, and the need for an equal opportunity for education support the need for clarification of the quality of distance education in biology, especially in the community college setting. Student attitudes, approaches to learning, and performance should all be studied in order to formulate a better evaluation of the quality and effectiveness of online courses (Svirko & Mellanby, 2008).

The purpose of this study was to …

Biology And Control Of The Bed Bug Cimex Lectularius L., Kevin Hinson

All Dissertations

After vanishing from the public eye for more than 50 years, bed bugs have resurged to become one of the most widely discussed and heavily researched insect pests in the westernized world. Our inability to prevent and successfully treat infestations has been the driving force behind this wave of research. I addressed gaps in our understanding of bed bugs by examining behavioral and life history characteristics, as well as insecticide application responses. I showed that natural-based products are generally ineffective against bed bugs, particularly when used as a residual treatment. I also found that bed bugs may be killed through …

Sex-Specific Distributions Of Leopard Sharks (Triakis Semifasciata) In An Estuarine Environment, Andrea Lynn Launer

Master's Theses

Estuaries are used seasonally by many elasmobranchs for reproduction and as nurseries. The character, location, and availability of elasmobranch habitats in estuaries are often altered by anthropogenic activities and environmental changes. These habitat changes may have different effects on groups within a shark population because sex-specific segregations are common for many elasmobranchs. Leopard Sharks (Triakis semifasciata) are important estuarine predators in California and exhibit sexual segregations. Movements of 13 Leopard Sharks (male n=6, female n=7) tagged with coded acoustic transmitters were monitored from March 14, 2013 to March 9, 2014 using moored receivers in Elkhorn Slough, CA. Movement patterns were …

Effects Of Depth, Site, And Season On Phenotypic Variation Of The Geniculate Coralline, Calliarthron Tuberculosum Around The Monterey Peninsula, California, Jasmine Elena Ruvalcaba

Master's Theses

Coralline algae are ubiquitous in near-shore marine environments. In particular, geniculate corallines occur in intertidal and subtidal habitats with abundances typically higher at shallow depths. Due to the high abundance of Calliarthron tuberculosum in Monterey kelp beds, this species was chosen to study effects of depth, site, and season on morphology and physiology. To further understand this pattern, populations from 3 and 10 m depth were sampled at two sites to examine morphometric variables including total length, total width, and number of branch tips as well as, physiological variables including respiration, photosynthetic, and calcification rates. Growth rates were also quantified …

Um Professor Talks Turkeys On Npr Today, Staff Report

University of Mississippi News

Richard Buchholz will talk about his research of the mating habits of America's favorite Thanksgiving bird

An Active Role For The Ribosome In Determining The Fate Of Oxidized Mrna, Carrie L. Simms, Benjamin H. Hudson, John W. Mosior, Ali S. Rangwala, Hani S. Zaher

Biology Faculty Research

Chemical damage to RNA affects its functional properties and thus may pose a significant hurdle to the translational apparatus; however, the effects of damaged mRNA on the speed and accuracy of the decoding process and their interplay with quality-control processes are not known. Here, we systematically explore the effects of oxidative damage on the decoding process using a well-defined bacterial in vitro translation system. We find that the oxidative lesion 8-oxoguanosine (8-oxoG) reduces the rate of peptide-bond formation by more than three orders of magnitude independent of its position within the codon. Interestingly, 8-oxoG had little effect on the fidelity …