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Microhabitats In An Urban Greenspace: Function In The Beauty, Kalie Schultz Apr 2021

Microhabitats In An Urban Greenspace: Function In The Beauty, Kalie Schultz

Honors Projects

This project combines science with art, with a focus on microhabitats in a unique natural space in an urban area. It is set in the Highlands Nature Preserve and the mediums used are photography and digital illustration. The goal of the project is to bring the viewer in from a wide, landscape perspective into a more close and detailed perspective of the multiple microhabitats that exist in the nature preserve. It shows how beauty can be hiding in plain sight for anyone to see if they look close enough. It also aims to show how the beauty is not just …


Osmosis - Spring 2020 Mar 2021

Osmosis - Spring 2020

Osmosis Magazine

Osmosis is a student read, led, and written publication from the University of Richmond, focusing on all aspects of healthcare and science.


Effects Of Varying Heat Indexes On Habitat Utilization And Behavior On Captive Red-Ruffed Lemurs (Varecia Rubra), Jeffrey Gammon Mar 2021

Effects Of Varying Heat Indexes On Habitat Utilization And Behavior On Captive Red-Ruffed Lemurs (Varecia Rubra), Jeffrey Gammon

The Pegasus Review: UCF Undergraduate Research Journal

The two captive red-ruffed lemurs (Varecia rubra) at the Central Florida Zoo experienced a more temperate climate and utilized a differing habitat than they would in their native range, Madagascar. Proper management of the species in captivity is crucial for its long-term survival as they are critically endangered. Over a four month period, heat index temperature, lemur behavior, and habitat utilization data were collected via an instantaneous scan sample. Variables were analyzed to characterize how variations in heat index alter habitat utilization and behavior of the captive lemurs. As the heat index increased, habitat use became more restricted …


Getting Radical: Feminism, Patriarchy, And The Sexual-Exploitation Industries, Robert Jensen Mar 2021

Getting Radical: Feminism, Patriarchy, And The Sexual-Exploitation Industries, Robert Jensen

Dignity: A Journal of Analysis of Exploitation and Violence

The sexual-exploitation industries, including prostitution and pornography, are patriarchal institutions that are inconsistent with dignity, solidarity, and equality. Radical feminism offers a compelling analysis not only for women but also for men striving to be fully human.


Observational Study Of Two Ex Situ North American River Otters (Lontra Canadensis), Julia Rifenberg Feb 2021

Observational Study Of Two Ex Situ North American River Otters (Lontra Canadensis), Julia Rifenberg

The Pegasus Review: UCF Undergraduate Research Journal

Zoos enable the ability to study how captive conditions impact the behaviors of animals. In this study, I observed two North American river otters housed at the Central Florida Zoo to evaluate behavioral changes after the male had been removed from the female for a month-long medical examination. The aim of this study was to 1) determine if mating behaviors were still occurring between the two river otters following the male’s removal and 2) to assess the welfare of the male and female river otters in captivity by observing their interactions and individual behaviors. Observed behaviors were compared to documented …


Japanese Quail (Coturnix Japonica) As A Novel Model To Study The Relationship Between The Avian Microbiome And Microbial Endocrinology-Based Host-Microbe Interactions, James Keane, Joshua M. Lyte, Julia Eckenberger, Nicholas Anthony, Sandip Shrestha, Daya Marasini, Karrie M. Daniels, Valentina Caputi, Annie M. Donoghue, Mark Lyte Feb 2021

Japanese Quail (Coturnix Japonica) As A Novel Model To Study The Relationship Between The Avian Microbiome And Microbial Endocrinology-Based Host-Microbe Interactions, James Keane, Joshua M. Lyte, Julia Eckenberger, Nicholas Anthony, Sandip Shrestha, Daya Marasini, Karrie M. Daniels, Valentina Caputi, Annie M. Donoghue, Mark Lyte

Articles

Background

Microbial endocrinology, which is the study of neuroendocrine-based interkingdom signaling, provides a causal mechanistic framework for understanding the bi-directional crosstalk between the host and microbiome, especially as regards the effect of stress on health and disease. The importance of the cecal microbiome in avian health is well-recognized, yet little is understood regarding the mechanisms underpinning the avian host-microbiome relationship. Neuroendocrine plasticity of avian tissues that are focal points of host-microbiome interaction, such as the gut and lung, has likewise received limited attention. Avian in vivo models that enable the study of the neuroendocrine dynamic between host and microbiome are …


Japanese Quail (Coturnix Japonica) As A Novel Model To Study The Relationship Between The Avian Microbiome And Microbial Endocrinology-Based Host-Microbe Interactions, Joshua M. Lyte, James Keane, Julia Eckenberger, Nicholas Anthony, Sandip Shrestha, Daya Marasini, Karrie M. Daniels, Valentina Caputi, Annie M. Donoghue, Mark Lyte Feb 2021

Japanese Quail (Coturnix Japonica) As A Novel Model To Study The Relationship Between The Avian Microbiome And Microbial Endocrinology-Based Host-Microbe Interactions, Joshua M. Lyte, James Keane, Julia Eckenberger, Nicholas Anthony, Sandip Shrestha, Daya Marasini, Karrie M. Daniels, Valentina Caputi, Annie M. Donoghue, Mark Lyte

Department of Computer Science Publications

Microbial endocrinology, which is the study of neuroendocrine-based interkingdom signaling, provides a causal mechanistic framework for understanding the bi-directional crosstalk between the host and microbiome, especially as regards the effect of stress on health and disease. The importance of the cecal microbiome in avian health is well-recognized, yet little is understood regarding the mechanisms underpinning the avian host-microbiome relationship. Neuroendocrine plasticity of avian tissues that are focal points of host-microbiome interaction, such as the gut and lung, has likewise received limited attention. Avian in vivo models that enable the study of the neuroendocrine dynamic between host and microbiome are needed. …


In Silicoidentification Of Toxins And Their Effect Onhost Pathways: Feature Extraction, Classificationand Pathway Prediction., Rishika Sen Dr. Jan 2021

In Silicoidentification Of Toxins And Their Effect Onhost Pathways: Feature Extraction, Classificationand Pathway Prediction., Rishika Sen Dr.

Doctoral Theses

Identification of toxins, which are either proteins or small molecules, from pathogens is of paramount importance due to their crucial role as first-line invaders infiltrating a host, often leading to infection of the host. These toxins can affect specific proteins, like enzymes that catalyze metabolic pathways, affect metabolites that form the basis of metabolic reactions, and prevent the progression of those pathways, or more generally they may affect the regular functioning of other proteins in signaling pathways in the host. In this regard, the thesis addresses the problem of identification of toxins, and the effect of perturbations by toxins on …


Identification And Report Of Parasites Trematoda And Acanthocephala Found In Fulica Americana From Oconto, Wisconsin, Regan Borowski Jan 2021

Identification And Report Of Parasites Trematoda And Acanthocephala Found In Fulica Americana From Oconto, Wisconsin, Regan Borowski

Student Presentations

This project focuses on the morphological and molecular characterization of two parasites, a thorny-headed worm (Acanthocephala) and an intestinal trematode fluke (Neoleucochloridium) from the American Coot, Fulica americana, from Oconto, Wisconsin. The bird was necropsied, parasites were extracted and fixed for morphology and DNA sequence analysis. Techniques used included: DNA extraction, amplification of target genes (28S rRNA gene), staining to prepare whole mounts and Scanning Electron Microscopy (SEM). The acanthocephalan species was identified as Polymorphus trochus and single trematode was identified as Neoleucochloridium. This is the first DNA sequence data for Neoleucochloridium.


Analysis Of Amur Honeysuckle Stem Density As A Function Of Spatial Clustering, Horizontal Distance From Streams, Trails, And Elevation In Riparian Forests, Greene County, Ohio, Greg Michael Grierson Jr. Jan 2021

Analysis Of Amur Honeysuckle Stem Density As A Function Of Spatial Clustering, Horizontal Distance From Streams, Trails, And Elevation In Riparian Forests, Greene County, Ohio, Greg Michael Grierson Jr.

Browse all Theses and Dissertations

The non-native invasive shrub Amur honeysuckle, Lonicera maackii (Rupr.) Herder (Gorchov and Trisel, 2003), is one of the most prolific invasive plant species across Midwestern and Northeastern landscapes of the United States. The locations of 2,095 individual Amur honeysuckle stems were geolocated using handheld GPS units in the understory of mixed growth forests at two study sites located approximately 5 km apart in northwestern Greene County, OH. Each site has undergone different levels of anthropogenic disturbance through time. The stem position data was used to measure the spatial clumping distribution and the density of Amur honeysuckle. The spatial clumping of …


Characterization Of Inhbb, Heatr5a, & Cyp2s1 Expression In Dorsal Root Ganglia By In-Situ Hybridization, Joshua D. Krech Jan 2021

Characterization Of Inhbb, Heatr5a, & Cyp2s1 Expression In Dorsal Root Ganglia By In-Situ Hybridization, Joshua D. Krech

Browse all Theses and Dissertations

Multiple studies have shown that gene expression changes occur in sensory neurons after peripheral nerve injury (PNI). These expression changes include many genes that are turned on specifically in response to injury, but much less is know about expression changes in stable genetic markers of particular sensory neuron populations. This study characterized the expression of three markers of proprioceptive neurons Inhbb, Heatr5a, Cyp2s1 in lumbar dorsal root ganglion (DRG) neurons in intact animals and after PNI. To perform these experiments, we subcloned segments of the coding sequences of these genes and generated DIG-labeled riboprobes. Control experiments demonstrated the validity of …


Altered Skeletal Muscle Excitation-Contraction Coupling In The R6/2 Transgenic Mouse Model For Huntington's Disease, Daniel R. Miranda Jan 2021

Altered Skeletal Muscle Excitation-Contraction Coupling In The R6/2 Transgenic Mouse Model For Huntington's Disease, Daniel R. Miranda

Browse all Theses and Dissertations

Huntington’s disease (HD) has classically been categorized as a neurodegenerative disorder. However, the expression of the disease-causing mutated huntingtin gene in skeletal muscle may contribute to the symptoms of HD, namely those that involve involuntary muscle contraction. In the R6/2 transgenic mouse model of HD, we previously observed ion channel defects that could contribute to involuntary muscle contraction. Here, in R6/2 muscle we investigated the consequence of these ion channel defects on action potentials (APs), the first step in excitation-contraction (EC) coupling. We found that the ion channel defects were associated with depolarizing the baseline membrane potential during AP trains. …


Change And Continuity In Biology, Gunnar O'Neill Babcock Jan 2021

Change And Continuity In Biology, Gunnar O'Neill Babcock

Legacy Theses & Dissertations (2009 - 2024)

This dissertation considers various examples of change and continuity in biology. In particular, it focuses on the conceptual possibilities during the fission of microorganisms and genes when they multiply or replicate. Among the kinds of conceptual revision that are outlined in the first two chapters, the three chapter argues that certain concepts such as death, reproduction and organism have limited applicability in certain domains of biology. The fourth chapter investigates whether synthetic genomes should be considered parts of genetic lineages. It concludes that synthetic genomes are parts of the lineages upon which they were modeled. The final chapter aims to …


Composition And Homology In The Taxonomic Classification Of Escherichia Coli, Tanya Irani Jan 2021

Composition And Homology In The Taxonomic Classification Of Escherichia Coli, Tanya Irani

Theses and Dissertations (Comprehensive)

As new techniques have been introduced, specifically the possibility of complete genome sequencing, better methods of defining bacterial species have also been proposed. One of the most recently proposed methods, using bioinformatic techniques, is to calculate the average nucleotide identity (ANI) between the homologous genome segments of different isolates. Another method for species discrimination that has been tested successfully is the similarity of DNA compositional signatures. However, in a recent update, DNA signatures split the available Escherichia coli complete genomes into three groups. To check if this result was consistent with such genomes belonging to different species, we tested methods …


The Effect Of Endogenous Ligands Of The Aryl Hydrocarbon Receptor On Antibody Expression In A Human B-Cell Model, Valerie Benedict Jan 2021

The Effect Of Endogenous Ligands Of The Aryl Hydrocarbon Receptor On Antibody Expression In A Human B-Cell Model, Valerie Benedict

Browse all Theses and Dissertations

Small changes in antibody expression have broad impacts on human health and disease. An environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces profound immune suppression in animal models in an aryl hydrocarbon receptor (AhR)-mediated fashion. In a human Burkitt's lymphoma cell line (CL-01), TCDD inhibited IgG secretion and differentially impacted Ig heavy chain expression. In addition to TCDD, the AhR has several endogenous, dietary, and bacterial ligands such as 6-formylindolo[3,2-b]carbazole (FICZ) and indole, which are present within the human body at varied concentrations (0.30 mM- 6.64 mM). Both FICZ (100 nM) and indole (100 µM) significantly reduced IgG secretion. Overall antibody secretion is …


The Biopolitics Of Maskless Police, India Thusi Jan 2021

The Biopolitics Of Maskless Police, India Thusi

Articles by Maurer Faculty

Despite the recent movement against police violence, police officers have been endangering their communities by engaging in a new form of violence— policing while refusing to wear facial coverings to prevent the spread of COVID-19. Many states advise people to wear masks and to socially distance when in public spaces. However, police officers have frequently failed to comply with these guidelines as they interact with the public to enforce these COVID-19 laws. Police enforcement of COVID-19 laws is problematic for two reasons: (1) it provides a method for pathologizing marginalized communities as biological threats; (2) it creates a racialized pathway …


Kean Program Review - Ba Biology 2019, Kean University Jan 2021

Kean Program Review - Ba Biology 2019, Kean University

Evidence Inventory

Kean Program Review - BA Biology 2019


Determining Environmental Changes Using Time Lapse Photography, Emily Lemasters Jan 2021

Determining Environmental Changes Using Time Lapse Photography, Emily Lemasters

Williams Honors College, Honors Research Projects

This paper aims to use photographs throughout several years to observe, examine, and make conclusions on changes occurring at different areas of the Bath Nature Preserve. Throughout the years 2013-2021, photographs have been captured at roughly the same angle at multiple locations in the preserve. These photographs will be placed into a time lapse video and examined to physically see how the environment is changing. Changes to the environment could be natural or as a result of outside factors. By examining these changes, it can be determined if alterations need to be made to help the environment thrive. Two specific …


Change In The Behaviors And Spatial Use Of Canada Lynx (Lynx Canadensis) Over Time At John Ball Zoo, Hailee Cederquist Jan 2021

Change In The Behaviors And Spatial Use Of Canada Lynx (Lynx Canadensis) Over Time At John Ball Zoo, Hailee Cederquist

Student Summer Scholars Manuscripts

Felines are popular attractions at zoos across the country, even more so when young animals are involved. As such caretakers strive to ensure that their animal’s needs are met, and individuals display healthy behaviors and activity levels in comparison to their wild counterparts (Mcphee & Carlstead, 2010). However, cats, being wide-ranging carnivores, are known to be prone to stereotypical behaviors which can be detrimental to an animal’s health (Clubb & Mason, 2003). At John Ball Zoo in Grand Rapids, Michigan, we observed the behaviors and spatial use of 3 Canada lynx (Lynx canadensis) during the summer of 2020; an adult …


Analyses Of Coyote (Canis Latrans) Consumption Of Anthropogenic Material And Dietary Composition In Urban And Non-Urban Habitats, Audrey A. Hayes Jan 2021

Analyses Of Coyote (Canis Latrans) Consumption Of Anthropogenic Material And Dietary Composition In Urban And Non-Urban Habitats, Audrey A. Hayes

Browse all Theses and Dissertations

Coyotes are a generalist species that have adapted to nearly every terrestrial habitat in the United States. The species’ success is heavily attributed to their omnivorous diets and tolerance for environments that are regularly disturbed. Because the larger predator species that typically act as apex predators are sensitive to highly fragmented landscapes, the coyote is the functioning apex predator in many ecosystems where large predators, such as wolves, have been extirpated. The coyotes’ ecological role in urban ecosystems has received much attention in the last few decades as the species’ presence in cities and suburbs has increased, along with human-coyote …


Altered Skeletal Muscle Excitation-Contraction Coupling In The R6/2 Transgenic Mouse Model For Huntington's Disease, Daniel R. Miranda Jan 2021

Altered Skeletal Muscle Excitation-Contraction Coupling In The R6/2 Transgenic Mouse Model For Huntington's Disease, Daniel R. Miranda

Browse all Theses and Dissertations

Huntington’s disease (HD) has classically been categorized as a neurodegenerative disorder. However, the expression of the disease-causing mutated huntingtin gene in skeletal muscle may contribute to the symptoms of HD, namely those that involve involuntary muscle contraction. In the R6/2 transgenic mouse model of HD, we previously observed ion channel defects that could contribute to involuntary muscle contraction. Here, in R6/2 muscle we investigated the consequence of these ion channel defects on action potentials (APs), the first step in excitation-contraction (EC) coupling. We found that the ion channel defects were associated with depolarizing the baseline membrane potential during AP trains. …


Characterizing The Effects Of 14-3-3 Isoforms On Alpha-Synuclein Toxicity In A Yeast Model, Angela Marie Braunschweiger Jan 2021

Characterizing The Effects Of 14-3-3 Isoforms On Alpha-Synuclein Toxicity In A Yeast Model, Angela Marie Braunschweiger

Browse all Theses and Dissertations

The presynaptic protein alpha-synuclein encoded by SNCA is the primary component of Lewy bodies and Lewy neurites which are the histopathological hallmarks of Parkinson’s disease. While the etiology of Parkinson’s remains unclear, SNCA mutations and copy number variations are one of several genes linked to Parkinson’s. The family of highly conserved chaperone proteins 14-3-3 have been shown to co-aggregate and share regions of 40% homology with alpha-synuclein. Mitochondrial dysfunction also plays a role in Parkinson’s disease with abnormalities in mitochondrial respiration due to interference of complex I in the electron transport chain being found in Parkinson’s patients. Alpha-synuclein increases fragmentation …


Changes In The Vertical Stratification Of Neotropical Nymphalidae At Forest Edges In Relation To Light And Temperature Conditions, Brian Koji Oye Jan 2021

Changes In The Vertical Stratification Of Neotropical Nymphalidae At Forest Edges In Relation To Light And Temperature Conditions, Brian Koji Oye

University of the Pacific Theses and Dissertations

The composition of neotropical fruit-feeding nymphalid butterflies assemblages often varies by location and stratum within a forest. Recent work has shown that vertical stratification in particular may serve as barrier to gene flow, indicating the potential role vertical stratification may play in evolution. At forest edges, the distinction between assemblages has been described to decrease, with species considered to be canopy specialists descending to the forest understory. The similarity in light conditions between the canopy and understory strata at edges or disturbed habitat is hypothesized to be responsible for this phenomenon. We conducted a study using standardized sampling to document …


Patterns Of Genetic Divergence Across Geographically Variable Populations Of Xanthisma Gracile (Asteraceae), Lavanya Challagundla, Lisa E. Wallace Jan 2021

Patterns Of Genetic Divergence Across Geographically Variable Populations Of Xanthisma Gracile (Asteraceae), Lavanya Challagundla, Lisa E. Wallace

Biological Sciences Faculty Publications

Premise of research. Numerous biotic and abiotic factors can contribute to local selection and lead to geographic structure and genetic divergence between populations. The southwestern United States contains many distinctive plant communities, ranging from woodlands to desert scrub, that are shaped by species adapting to local variation in elevation, precipitation, seasonality, and soils. Given this variation, species occurring across diverse habitats are expected to harbor high genetic diversity and exhibit significant genetic differences associated with environmental variation.

Methodology. Here, we studied the genetic divergence of populations of Xanthisma gracile (Asteraceae) across Arizona using amplified fragment length polymorphisms and evaluated associations …


Will There Be Changes In Sexually Differentiated Behaviors In Mice Manipulated For The Sry Gene As They Mature Into Adultood?, Subin Joo Jan 2021

Will There Be Changes In Sexually Differentiated Behaviors In Mice Manipulated For The Sry Gene As They Mature Into Adultood?, Subin Joo

CMC Senior Theses

Sexually differentiated behavior has been shown to be affected by both genes and hormones. The discovery of the SRY gene, which codes for the development of testes, lead to the development of the Four Core Genotypes model of mice, and the separation of sex chromosomes and its resulting gonadal hormones. Using the FCG model, this study aims to look at the development of sexually differentiated behavior in mice, and track how it changes throughout their life. FCG mice will be divided into individual and social housing, and repeated experiments carried out to test their reaction to both intact female and …


The Cottonwood Ranch Riparian Management Case Study, Sherman Swanson, Kent Mcadoo, Agee Smith, Sandra Wyman Dec 2020

The Cottonwood Ranch Riparian Management Case Study, Sherman Swanson, Kent Mcadoo, Agee Smith, Sandra Wyman

IGC Proceedings (1977-2023)

No abstract provided.


Low-Intensity Vibration Restores Nuclear Yap Levels And Acute Yap Nuclear Shuttling In Mesenchymal Stem Cells Subjected To Simulated Microgravity, Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer Dec 2020

Low-Intensity Vibration Restores Nuclear Yap Levels And Acute Yap Nuclear Shuttling In Mesenchymal Stem Cells Subjected To Simulated Microgravity, Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Reducing the musculoskeletal deterioration that astronauts experience in microgravity requires countermeasures that can improve the effectiveness of otherwise rigorous and time-expensive exercise regimens in space. The ability of low-intensity vibrations (LIV) to activate force-responsive signaling pathways in cells suggests LIV as a potential countermeasure to improve cell responsiveness to subsequent mechanical challenge. Mechanoresponse of mesenchymal stem cells (MSC), which maintain bone-making osteoblasts, is in part controlled by the “mechanotransducer” protein YAP (Yes-associated protein), which is shuttled into the nucleus in response to cyto-mechanical forces. Here, using YAP nuclear shuttling as a measurement outcome, we tested the effect of 72 h …


Illegal Killing Of Nongame Wildlife And Recreational Shooting In Conservation Areas, Jay D. Carlisle, Eve C. Thomason, James R. Belthoff, Julie A. Heath, Kristina J. Parker, Heather M. Hayes, Madeline C. Alberg, Sandra M. Amdor, Steven E. Alsup, Stephanie E. Coates Nov 2020

Illegal Killing Of Nongame Wildlife And Recreational Shooting In Conservation Areas, Jay D. Carlisle, Eve C. Thomason, James R. Belthoff, Julie A. Heath, Kristina J. Parker, Heather M. Hayes, Madeline C. Alberg, Sandra M. Amdor, Steven E. Alsup, Stephanie E. Coates

Intermountain Bird Observatory Publications and Presentations

Illegal killing of nongame wildlife is a global yet poorly documented problem. The prevalence and ecological consequences of illegal killing are often underestimated or completely unknown. We review the practice of legal recreational shooting and present data gathered from telemetry, surveys, and observations on its association with illegal killing of wildlife (birds and snakes) within conservation areas in Idaho, USA. In total, 33% of telemetered long‐billed curlews (Numenius americanus) and 59% of other bird carcasses found with known cause of death (or 32% of total) were illegally shot. Analysis of spatial distributions of illegal and legal shooting is …


Inheritability Of Ciprofloxacin-Induced Mitochondrial Mutations From Parental To Offspring Generation Using Quantitative Polymerase Chain Reaction, Rose Mccoy Oct 2020

Inheritability Of Ciprofloxacin-Induced Mitochondrial Mutations From Parental To Offspring Generation Using Quantitative Polymerase Chain Reaction, Rose Mccoy

Honors Program: Senior Projects (Public)

In all eukaryotes, mitochondria are known as the powerhouse of the cell (Siekevitz, 1957). In plants, however, their mitochondrial genome is especially strange. Plant mitochondrial genomes are extremely large and contain both linear and circular subgenomic DNA fragments. Plant mitochondrial genomes undergo a significant amount of mutations in the form of rearrangements. However, it is not known how often these rearrangements are inherited by the next generation. It is thought that plant cells that are still dividing have higher rates of DNA repair, such as double-strand break repair, to ensure the quality of that plant lineage. As follows, it is …


Cardiac Neuroanatomy And Chronotropic Modulation Of The Adult Giant Danio Heart, Alyssa Koch, Emma Nelson, Pascal Lafontant Oct 2020

Cardiac Neuroanatomy And Chronotropic Modulation Of The Adult Giant Danio Heart, Alyssa Koch, Emma Nelson, Pascal Lafontant

Annual Student Research Poster Session

Studies in non-mammalian models species have contributed significantly to our understanding of the biology and the nature of innervation in the heart. The giant danio (D. malabaricus) is a teleost fish species closely related to zebrafish, that is also capable of heart regeneration. We previously described the development and maturation of the giant danio (GD) heart. However, little is known about its innervation. We hypothesized that the pattern of innervation in the GD heart is anatomically and physiologically complex, and that the heart is responsive to physiological modulation similar to that seen in cyprinid fish and mammals. Using various neuronal …