Cognitive Behavioral Therapy-Based Psychosocial Interventions To Reduce Anxiety After Social Isolation In Adolescent Females, Bailey E. Noble

InnovateHER Meeting 2026

• COVID-19 social isolation linked with higher anxiety risk in adolescents, especially females
• Review examined whether CBT-based psychosocial interventions reduce anxiety after pandemic-related loneliness/social isolation
• Across 6 studies, remote and internet-delivered CBT linked with anxiety improvement 
• Strongest outcomes seen with therapist-assisted CBT
• Common barriers: privacy, motivation, scheduling, and digital access
• Nursing relevance: early screening, referral, and support for treatment participation

Acute And Chronic Oral Administration Of Cannabidiol-Dominant Cannabis Products: Sex- And Formulation-Dependent Effects On Anxiety-Like Behavioral Patterns In Rats, Carlos R. Maestas-Olguin

Psychology ETDs

Interest in the anxiolytic-like effects of cannabidiol (CBD), the non-intoxicating phytocannabinoid found within the genus, Cannabis, has grown significantly in recent years. However, preclinical investigations of CBD’s anxiolytic potential often elect to forgo translationally relevant models that maximize external validity in favor of greater internal and mechanistic validity. As a result, the effects of relatively low dose (< 3mg/kg) oral CBD administration on anxiety-like behaviors are not yet fully characterized. The present studies examined the impact of two orally delivered CBD-dominant cannabis products – a “full-spectrum” formulation derived from the whole plant and a CBD isolate derived from the same chemovar – on innate defensive behaviors exhibited by adult male and female rats in various tests of anxiety. Results indicated that acute and chronic low dose oral CBD administration attenuated anxiety-like behavior in rats, regardless of sex or formulation. These findings extend the growing corpus of literature describing anxiolytic-like effects of CBD.

The Contribution Of Psychophysiological Stress Factors On Muscle Cramp Susceptibility, Lauren D. Levine

UNLV Theses, Dissertations, Professional Papers, and Capstones

Exercise-associated muscle cramps (EAMCs) are painful phenomenon that involves involuntary muscle spasms occurring during physical activity or directly after. 1 The landscape of the research on EAMC etiology has expanded from focusing on a single prevailing cause (e.g., hydration status) to a more holistic approach of how numerous factors contribute to the onset of neuromuscular fatigue, and the significance of each factor in those who suffer from EAMC. Following the multifactorial theory of cramp pathophysiology, this research sought to advance the knowledge of cramp susceptibility by investigating if there is a relationship between common psychophysiological factors like high anxiety, sleep …

Mindfulness-Based Interventions: Improving Quality Of Care In Breast Cancer, Deborah Schindele

Group: Northern Arizona University School of Nursing, DNP Doctoral Papers

Breast cancer is the second leading cause of death in women and leads to decreased quality of life owing to increased anxiety, depression, fatigue, stress, and a lack of social support. The American Society for Integrative Oncology ranks mindfulness-based interventions (MBI) as the most highly recommended integrative interventions known to decrease anxiety, depression, and fatigue, and improve the quality of life of breast cancer patients. However, they were not regularly used or recommended by support group facilitators of the project. A quality improvement project was implemented with the five support group facilitators to address this deficit. The purpose was to …

Psychosocial Predictors Of Depression And Anxiety In Thai Stroke Caregivers, Chanatip Tongyonk, Sorawit Wainipitapong, Chavit Tunvirachaisakul, Aurauma Chutinet, Michael Maes, Thitiporn Supasitthumrong

Chulalongkorn Medical Journal

Background: Caregivers of stroke survivors often face significant psychological challenges, yet limited research in Thailand has explored how patient and caregiver characteristics jointly influence caregiver mental health outcomes.

Objective: To identify characteristics of ischemic stroke patients and their caregivers that may predict distress, sadness, and anxiety symptoms in the caregivers.

Method: To measure caregivers' burden, stress, depression, and anxiety symptoms, the Hospital Anxiety and Depression Scale (HADS), Zarit Burden Interview (22-item ZBI), and Perceived Stress Scale (PSS-10) were utilized. To define a multi-step mediation model, we used partial least squares structural equation modelling (PLS-SEM).

Result: 97 stroke patients and their …

The Mediating Effect Of Physical Activity On Mental Health Among Sexual Minority Adolescents During Covid-19, You Fu, Ryan D. Burns, Hayley Almes, Xiangren Yi, Nora Constantino

International Journal of Physical Activity and Health

Purpose: Adolescents identifying as a sexual minority frequently experience mental health issues exacerbated by the COVID-19 pandemic. Physical activity (PA) has numerous benefits for mental health and emotional development. The purpose of this study was to examine the mediating effect of PA on the association between sexual minority status and mental health among adolescents during COVID-19. Methods: A sample of adolescents (grades 9-12) completed the online Adolescent Behaviors and Experiences Survey (ABES; N = 7677; 49.6% male) in 2021. The independent variable in this study was a recorded binary response item asking about sexual orientation. The dependent variable was a …

The Use Of Tactile Stimulations To Mitigate Somatic Anxiety Responses: A Pilot Study, Abigail C. Robbins

Masters Theses

Anxiety is the body’s response to detected danger or stress. Physiological responses include shallow breathing, increased heart rate, sweating, shaking, and muscle tension. Roughly 33.7% of the population experiences anxiety, with approximately 40 million adults in the United States being affected by the disorder. Anxiety can create severe personal, social, and economic burdens. Traditional treatments of anxiety disorders such as medication and psychotherapy can be effective, but present multiple barriers such as cost, accessibility, and side effects. As a result, there is a growing industry for non-invasive, low-cost solutions that can help individuals regulate their physiological anxiety responses and reduce …

Discipline Or Damage? How Corporal Punishment Affects The Psychological Wellbeing Of Children In The School Setting, Umulkheir Mahamud Sharif Ali

Undergraduate Honors Theses

Corporal punishment continues to be used in many homes and schools despite research linking it to negative psychological outcomes in children. Previous studies, primarily focused on home settings, have associated corporal punishment with increased anxiety, depression, aggression, and emotional distress. However, less research has examined how these outcomes appear within school environments, where discipline occurs in more structured institutional settings. This thesis investigates how corporal punishment in schools affects students psychologically, emotionally, and academically through a literature review of peer-reviewed studies from psychology, education, and public health. The findings show that many of the mental health outcomes associated with corporal …

A Quality Improvement Initiative Evaluating Factors Influencing Patient Experience With Virtual Reality During Awake​ Interventional Radiology Procedures, Quynh Dao-Payne

Doctoral Projects

Procedural anxiety and pain are common among pediatric patients undergoing awake interventional radiology (IR) procedures and may negatively affect patient comfort, cooperation, and overall patient experience. Virtual reality (VR) has emerged as a promising nonpharmacologic intervention to reduce anxiety and improve patient-centered outcomes. The purpose of this quality improvement project was to evaluate patient-reported experiences and perceived outcomes associated with VR use during awake pediatric IR procedures at Children’s Hospital Los Angeles.​ A qualitative descriptive quality improvement design was utilized. Twenty pediatric​ patients ages 10–21 years undergoing awake IR procedures with VR as part of standard clinical​ care completed structured …

Mental Health Comorbidities And Ibd Outcomes In Patients Treated With Anti–Il-23 Therapy, Jashanveer S. Johal, Archana Salek, Mahmoud Al-Bataineh, Bianca Patel, Om Patel, Yecheskel Schneider, Jason Hyman, Abdallah Hussein

Rowan-Virtua Research Day

Background: Depression and anxiety are prevalent in inflammatory bowel disease (IBD) and may adversely influence outcomes. We evaluated the impact of comorbid mood disorders on clinical outcomes among IBD patients treated with anti–IL-23 agents.

Methods: Using a global de-identified electronic health record network, adults with Crohn's disease or ulcerative colitis initiating an anti–IL-23 agent were identified. Cohort 1 included patients with a documented mood disorder (depression and/or anxiety) at or prior to treatment initiation; Cohort 2 included those without mood disorders. Propensity score matching (1:1) on demographics and comorbidities yielded 3,546 patients per cohort. Primary outcomes included inpatient/ED encounters, abscess/fistula, …

Mental Health Comorbidities And Ibd Outcomes On Anti-Tnf Therapy, Jashanveer S. Johal, Mahmoud Al-Bataineh, Archana Salek, Bianca Patel, Om Patel, Jason Hyman, Yecheskel Schneider, Abdallah Hussein

Rowan-Virtua Research Day

Background: Depression and anxiety are prevalent in inflammatory bowel disease (IBD) and may adversely affect biologic therapy outcomes. We evaluated the impact of comorbid mood disorders on clinical outcomes among IBD patients treated with anti-TNF agents.

Methods: Using a global de-identified electronic health record network, adults with Crohn's disease or ulcerative colitis initiating an anti-TNF agent between 2018–2023 were identified. Cohort 1 included patients with a documented mood disorder (depression and/or anxiety) at or prior to anti-TNF initiation; Cohort 2 included those without mood disorders. Propensity score matching (1:1) on demographics and comorbidities yielded 9,605 patients per cohort. Primary outcomes …

A Retrospective Look At Self-Reported Mental Health Prevalence In Division Iii Student-Athletes, Jacob F. Neri

Masters Theses/Capstone Projects

Mental health concerns among collegiate athletes have gained increased attention, but there has been limited research focus on Division III student-athletes. This study aimed to examine the self-reported prevalence of anxiety, depression, anger, stalking/harassment, abuse/assault, alcohol/substance abuse, self-harm, suicide ideation, and suicide attempt to identify contributing factors amongst this population. A retrospective, cross-sectional study was conducted looking at data collected from the student-athlete mental health history & well-being questionnaire that was administered as part of their pre-participation exam (PPE) prior to the beginning of each academic year. A total of 554 Division III student-athletes were included in the study. Results …

The Relationship Between Sports Related Head Injuries, Mental Health And Academic Performance In University Student-Athletes, Odyssey Keller

Electronic Theses and Dissertations

Student athletes face many challenges when it comes to participating in team sports, one of the most notable being sport-related head injuries. Concussions are a growing concern since they have the potential to impact mental health and academic performance long-term. While many athletes report recovery within weeks, some continue to struggle with impairments in their psychological functioning and overall mental well-being that interferes with academic performance over time. Many of the standardized protocols in place for concussion management vary across institutions. This study aimed to address gaps in the existing literature by assessing concussion history, mental health and academic challenges …

Impact Of Escitalopram On Postpartum Sleep/Wake Activity And Maternal Behaviors, Kimberly Guerrero Leon

Electronic Theses, Projects, and Dissertations

The postpartum period is characterized by profound physiological and psychological changes, including disruptions in sleep and activity patterns, which may contribute to the onset of postpartum depression. If left untreated, postpartum depression can result in long-term consequences, including cognitive impairments, emotional dysregulation, impaired maternal-infant attachment, and the onset of sleep-related disorders. Selective serotonin reuptake inhibitor (SSRI), escitalopram, is prescribed for the treatment of postpartum depression due to its efficacy, favorable safety profile, and relatively low cost. While escitalopram is considered an effective treatment for depression and anxiety, far less is known about its impact on maternal behaviors during the postpartum …

Anxious Impairment: Exploring Executive Functions And Anxiety In College Students, Dawson C. Mathis

Masters Theses and Doctoral Dissertations

College students are tasked with juggling a variety of responsibilities. To manage these responsibilities college students must rely on their executive functioning (EF). Executive function refers to cognitive processes that are used to set goals, make plans to achieve those goals, and shift between tasks when necessary. A large portion of college students report experiencing anxiety and anxiety has been theorized to negatively impact cognitive performance, generally. This study sought to explore the impact of anxiety on inhibition and vigilance performance. Participants’ anxiety scores significantly correlated with the number of omission errors made on the inhibition task. Participants also made …

A Vicious Cycle: The Interplay Between Anxiety, Perfectionism, And Indecision, Kaelyn G. Moran

Psychological Science Undergraduate Honors Theses

Chronic indecisiveness is a pervasive issue that can negatively impact academic, occupational, and psychological functioning. Although prior research has identified anxiety and perfectionism as relevant correlates of indecisiveness, less is known about how these factors uniquely and jointly contribute to decision-making difficulties. The present study examined the relationships between trait anxiety, multidimensional perfectionism, and indecisiveness in a sample of 199 undergraduate students at the University of Arkansas. Participants completed self-report measures assessing anxiety (STICSA), perfectionism (Frost Multidimensional Perfectionism Scale), and indecisiveness (Revised Indecisiveness Scale). Zero-order correlations and multiple regression analyses were conducted to evaluate both overall and dimension-specific effects. Results …

Depression Symptoms Are Associated With Less Positively Biased Self-Ratings Of Attentional Control, Anna E. Morgan

Psychological Science Undergraduate Honors Theses

Deficits in the ability to flexibly direct, sustain, and shift attention, known as attentional control, have been linked to anxiety and depression. Attentional control supports engaging with goal-relevant stimuli while effectively disengaging from irrelevant or emotionally distracting stimuli. Thus, it is crucial in cognitive processes and emotional responses. Common measures of attentional control include behavioral tasks and self-report measures. However, behavioral and self-report measures are weakly correlated, suggesting that individuals generally are not good at perceiving their attentional control abilities. This mismatch between measures could be related to anxiety and depression symptoms. The goal of my project was to examine …

Exploring Exercise Motivation And Mental Well-Being In College Students, Elaine M. Lindesmith, Anqi Deng Dr

Health, Human Performance and Recreation Undergraduate Honors Theses

This study examined the relationship between physical activity, exercise motivation, and mental well-being among 48 undergraduate students at the University of Arkansas. Guided by Self-Determination Theory, the study used survey data to measure depression, anxiety, physical activity, and open-ended exercise motivation responses. Motivation responses were coded as autonomous or controlled.

Results showed that physical activity was weakly and negatively related to depression and anxiety, but these relationships were not statistically significant. There were also no significant differences in mental health between autonomous and controlled motivation groups, and motivation did not significantly predict mental health outcomes in regression analyses. Overall, the …

Development And Pilot Testing Of Transdiagnostic Exposure Therapy/Behavioral Activation For Autistic Adolescents With Internalizing Disorders, Andrew G Guzick, Elizabeth A Kaplan-Kahn, Jessica Szu-Chi Cheng, Callie Murphy, Ogechi C Onyeka, David Riddle, Tracy Dibbs, Leandra N Berry, Robin P Goin-Kochel, Eric A Storch

Faculty, Staff and Students Publications

Internalizing disorders disproportionately affect autistic adolescents, though limited research has focused on tailoring therapy for this population. The purposes of this paper were (1) to describe the development of a transdiagnostic exposure therapy/behavioral activation intervention for autistic adolescents with internalizing disorders, and (2) to present a pilot test of feasibility, acceptability, and efficacy of the intervention. The development of this therapy is described in detail, which prioritized the following domains: (1) building on the existing evidence base of exposure-based cognitive behavioral therapy for autistic youth with anxiety disorders, (2) involving caregivers considerably, (3) incorporating autism-specific considerations into case conceptualization and …

Psychological And Inflammatory Ties To Diet In Breast Cancer Survivors, Sonal Kaur Johal

Master's Theses

Breast cancer is among the most prevalent forms of cancer and is a primary cause of death among women (Wang et al., 2020). Cancer patients experience higher levels of anxiety symptoms, depressive symptoms, and inflammation compared to non-cancer patients, which can predict a diminished quality of life but also contribute to higher mortality rates among cancer patients (Bortolato et al., 2016; Song et al., 2022). Diet has the potential to impact the manifestation of depressive and anxiety symptoms in both healthy individuals and those battling cancer. This study explored the association between dietary habits, specifically cholesterol, fiber, saturated fat, added …

Dissociation, Anxiety, And The Vestibular System: Understanding The Impacts Of Anxiety, Panic, And Dissociation On The Vestibular System, Julian Achata

Honors Theses

Previous research indicates that vestibular dysfunction is associated with symptoms of anxiety, panic, and dissociation. The present study will investigate anxiety, panic, and dissociation symptoms and identify the connections between reported symptom severity and vestibular functionality. This study will focus on three different hypotheses: 1) higher levels of dissociation will correlate with increased vestibular disruption; 2) higher levels of anxiety will correlate with increased vestibular disruption; 3) higher levels of panic will correlate with increased vestibular disruption. Six virtually administered self-report measurements were used to identify the variables: Beck Anxiety Inventory (BAI), Depersonalization Derealization Inventory (DDI), Dissociation Experiences Scale-II (DES-II), …

Neuroprotective Effects Of Prophylactic Brivaracetam On Memory And Anxiety Following Traumatic Brain Injury, Sofia Dumic

Theses and Dissertations

Prophylactic brivaracetam (BRV) was evaluated in a rat TBI model for effects on behavior and serum tau. BRV reduced anxiety-like behavior with optimal dose-dependent effects at 2.1mg/kg, but did not affect working memory. Serum tau was detectable early post-injury, supporting its use as a biomarker.

Perceived Campus Safety And Psychological Flexibility As Moderators Of Posttraumatic Stress And Anxiety Following Indirect Exposure To School Gun Violence, Samara Trout

Honors Theses

The growing prevalence of gun violence in school settings within the United States, combined with extensive media coverage of these events, has heightened concerns regarding the psychological impact of indirect trauma exposure among students. The present study examined associations between indirect exposure to gun-based school violence and symptoms of posttraumatic stress and anxiety among undergraduate students at Western Michigan University (WMU). A secondary aim was to explore whether perceived safety and psychological flexibility/inflexibility moderated associations between indirect exposure and psychological distress. Using a cross-sectional correlational design, undergraduate students (N = 33) completed a self-report survey containing screening assessments, attention …

Serotonin 7 Receptor Modulation On Measures Of Working Memory And Anxiety, Antonio Gutierrez

Electronic Theses, Projects, and Dissertations

Serotonin (5-HT) function is critical in the regulation and homeostasis of several neural systems. Alterations in 5-HT levels can directly impact the presence of neuropsychiatric disorders such as schizophrenia. With a wide range of 5-HT receptors, the potential impact each of these modulators have on behavior is important to better understand. The 5-HT7 receptor is the most recently identified 5-HT receptor. 5-HT7 receptors can be found in the thalamus, hypothalamus, and several areas of the hippocampus. Modulation of these receptors impact circadian rhythms, hormonal regulation and memory function. Previous research has that 5-HT7 antagonist compounds lead to conflicting results, highlighting …

Social Media’S Impact On School-Aged Children's Mental Symptoms, Tiffany Espinoza

Electronic Theses, Projects, and Dissertations

With the increased usage of social media among individuals, this has raised concerns about its impact on the mental health symptoms of the younger population. Previous research has shown the impact of social media on adolescents' depression and anxiety; however, there is limited research showing the impact on younger school-aged children. The purpose of this study will be to examine the relationship between social media use and mental health symptoms among school-aged children from kindergarten through twelfth grade. The proposed research study will seek to address gaps in previous research by analyzing a wider age range and more diverse subgroups …

Investigating Fentanyl-Xylazine Interactions: Implications For Opioid-Induced Hyperalgesia And Affective Dysregulation In Rats, Alejandra R. Lujan

Electronic Theses, Projects, and Dissertations

The growing prevalence of fentanyl adulterated with xylazine presents a major public health concern, yet the behavioral and physiological effects of this combination remain poorly characterized. This study examined the effects of acute fentanyl administration, alone and in combination with xylazine, on opioid-induced hyperalgesia, affective behavior, and mortality in male and female Sprague-Dawley rats (n=80). Rats received four fentanyl injections (60 µg/kg) administered at 15-minute intervals, with or without xylazine (0, 0.1, 0.333, or 1.0 mg/kg), as well as a saline control condition. Pain sensitivity was assessed using a hot plate assay at 6.5, 12, 24, and 48 hours post-injection. …

University Student Mental Health: Service Utilization, Equity Gaps, And Strategies To Improve Access, Richard Mutua Kilonzo

Electronic Theses and Dissertations

Student mental health and access to care are pressing concerns in higher education. This study assesses mental health outcomes and access to campus mental health services at East Tennessee State University. Survey data from the 2023–2024 Healthy Minds Study were analyzed to report the prevalence of depression, anxiety, and suicidal ideation across the student population. The study evaluates disparities in these outcomes and barriers to care across student groups, with particular attention to equity-impacted students, especially sexual and gender minority students.

Findings indicate widespread psychological distress alongside persistent barriers, including long wait times, limited-service availability, and stigma-related concerns. These barriers …

Feasibility Of Assessing Dietary Patterns And Anxiety In College Students: A Pilot Study Using Nutrition Questionnaires, Gad-7, And Asq, Kylie Ford

Electronic Theses and Dissertations

Anxiety is highly prevalent among college students representing a significant public health concern. Research indicates that dietary patterns may influence mental health outcomes; however, the practicality of collecting comprehensive dietary and psychological data in college populations remains unclear. This pilot study assessed the feasibility of evaluating dietary patterns and anxiety using self-report instruments. Participants completed the Nutrition and Eating Habit questionnaire, the Generalized Anxiety Disorder-7 (GAD-7), and the Anxiety Sensitivity Questionnaire (ASQ). Although twenty-one students were recruited, survey completion rates were low, with only seven participants completing the nutrition questionnaire necessary to calculate the Dietary Inflammatory Index (DII). Descriptive analyses …

Assessing The Mental Wellness Of Professional Pilots And Their Willingness To Seek Professional Help, Bill Deng Pan, Flavio A. C. Mendonca Ph.D.

International Journal of Aviation, Aeronautics, and Aerospace

Professional pilots face distinct mental health challenges arising from irregular schedules, fatigue, high responsibility, and the need to maintain medical certification. These factors contribute to elevated stress, anxiety, and depression, while concerns about stigma, confidentiality, and potential career consequences often discourage pilots from seeking professional psychological support. As a result, barriers to early identification and intervention of mental health challenges remain a persistent concern within the aviation industry. This ongoing study utilizes a non-experimental, survey-based design to examine the mental wellness of professional pilots worldwide and their willingness to seek mental health support. The survey includes demographic items, standardized mental …

Three Deep Breaths, Gillianne Lisa B. Corpuz

Capstone Projects and Master's Theses

Today’s youth are experiencing higher rates of stress and anxiety, especially those that are system-involved and/or at-risk. The Epicenter of Monterey County is a one-stop resource center for system-involved and/or at-risk youth ages 14-24 to receive support with housing, health/wellness, employment and education. The project is aimed to support The Epicenter’s health/wellness aspect. This capstone project serves the purpose of providing both the staff and community youth members at The Epicenter with an opportunity to learn an accessible way to take care of themselves, both body and mind. This would be done through a series of workshops walking through a …