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Articles 7801 - 7830 of 10802
Full-Text Articles in Entire DC Network
Kerce, Rosann (Fa 909), Manuscripts & Folklife Archives
Kerce, Rosann (Fa 909), Manuscripts & Folklife Archives
Folklife Archives Finding Aids
Finding aid only for Folklife Archives Project 909. Project titled: “Popular Beliefs of Today.” Project includes note cards with brief descriptions of beliefs in Logan, Mercer and Oldham Counties in Kentucky. Note cards include a brief description of belief, informant’s name, and the motif index number.
Where's The Pair? A Spotting Book, Sydnee Burr
Where's The Pair? A Spotting Book, Sydnee Burr
Children's Book and Media Review
In this book of discovery, children have a challenge on every page. Each page has a rhyme and a task, such as finding the two cats who match out of an entire page of cats. Great for learning and inquisitive minds, this spotting book will keep children and parents quietly entertained.
If You Want To See A Whale, Liz Kazandzhy
If You Want To See A Whale, Liz Kazandzhy
Children's Book and Media Review
A boy and his dog go on an adventure to see a whale. Using his imagination, he and his canine friend go to the seaside, only to be distracted by a curious bird, sweet pink roses, possible pirates, a sitting pelican, a scooting caterpillar, and floating clouds. But they try to pay little attention to these fascinating things, and soon they row into the sea to wait, wait, and wait… until they finally see a whale!
Hedgehug's Halloween, Whitney Troxel
Hedgehug's Halloween, Whitney Troxel
Children's Book and Media Review
Hedgehug completely forgot about Reginald's Halloween party and he has no costume. He goes to each of his friends for help, but the costumes either rip, pop, or fall apart. Discouraged, Hedgehug decides to go home. His friend's work together to come up with the perfect costume for Hedgehug. Hedgehug goes to the party as a cactus and everyone cheers.
Darkbeast, Tessa Mcmillan
Darkbeast, Tessa Mcmillan
Children's Book and Media Review
Like all the children in Keara’s world, she was blessed with an animal companion or darkbeast at her birth. The darkbeast has a magical connection to take upon themselves the faults and flaws of their human child. At the age of twelve, children sacrifice their darkbeasts to show they have left childhood and entered adulthood. But when Keara turns twelve, she cannot kill her darkbeast, Caw. Her failure causes her family to shun her and sets the religious order of the Inquisitors after her. She runs away with Caw and joins a caravan of actors called the Travelers. She keeps …
Because Your Grandparents Love You, Liz Kazandzhy
Because Your Grandparents Love You, Liz Kazandzhy
Children's Book and Media Review
A little boy and girl have headed to the farm to visit their grandparents, but it doesn’t take long for them to get into mischief! As kids will be kids, these two end up stepping in manure by accident, trying to carry a huge bale of hay by themselves, spooking a hen while looking for eggs, peeling apples all wrong, and lighting a very smoky fire. At every turn and with every problem, Grandpa and Grandpa could react by reprimanding the kids or doing the job themselves, but they don’t—they patiently and kindly help their dear grandkids, and everyone works …
Bats At The Beach, Chelsie Troxel
Bats At The Beach, Chelsie Troxel
Children's Book and Media Review
When the day ends all of the bats come out to play! On this particular night, the moon is just right for a night at the beach. The bats gather up their supplies and luggage and head from the sky down to the sandy shores. They have so many fun things to do in the sand and the water. They make new friends with other animals that join them for a beach night. They surf and sail, play games and snack. When the sun starts to rise the bats say good bye to their friends and fun then quickly fly …
Who Sleeps, Cat The Cat?, Liz Kazandzhy
Who Sleeps, Cat The Cat?, Liz Kazandzhy
Children's Book and Media Review
Energetic and spunky Cat the Cat rounds up his other animal friends for bedtime. Sheep, Pig, Giraffe, Crab, Horse, and Shark are all doing their own nighttime activities, but follow Cat’s invitation to go to sleep. Owl, on the other hand, is just waking up.
Animal Friends: Elephants, Whitney Troxel
Animal Friends: Elephants, Whitney Troxel
Children's Book and Media Review
Animal Friends: Elephants gives several facts about elephants including their physical characteristics and lifestyles. It talks about the organization of elephant herds, which are lead by the oldest female. It also talks about how elephants care for each other by slowing down when another elephant is injured. The book also includes a brief list of facts not mentioned in the narrative as well as a glossary of terms found in the book.
A Moose That Says Moooooooooo, Chelsie Troxel
A Moose That Says Moooooooooo, Chelsie Troxel
Children's Book and Media Review
While reading about animals in her books, a little girl with an avid imagination thinks of every silly possible way she could have a unique zoo of her own. She thinks up animals doing all sorts of funny things like cooking, reading, and dancing. Then things start to get a little crazy with the animals a little out of control. The little girl then has to get involved and clean up this mess she has made. This adventure in her imagination is so exhausting she decided not to do it again, then of course, she thinks up another idea!
Marty And Grace #3: Chupacabra
Marty And Grace #3: Chupacabra
Children's Book and Media Review
Ever since Grace left with her grandfather, Noah Blackwood, Marty never felt Grace was safe. While all the adults of eWolfe are gone, Marty, Luther, and their new friend, Dylan, decide to rescue Grace and the Mokélé-mbembé hatchlings from Noah’s zoo, Seattle Ark. Meanwhile, Grace has been searching for any information exposing Blackwood. When she uncovers secret passageways in Noah’s mansion, they lead Grace to Noah’s private quarters and his secret taxidermy display of extinct animals. While there, Grace sees evidence that the boys are inside the zoo. She follows their trail and joins them in rescuing the hatchlings and …
The Animal Book
Children's Book and Media Review
The Animal Book is first and foremost educational. It breaches in depth animal kingdom subjects, defining words, classifications and habitual practices. Flipping through the pages will aid in discovering more about the world around you as well as animals you’ve never seen in real life or even heard of.
The Abc Animal Orchestra
Children's Book and Media Review
The Animal Orchestra is here to help kids learn their ABC’s! Every letter is “played” by a different member of the animal kingdom on instruments and with sounds from around the world. For example, “T is for TURTLE tooting his TUBA. It’s also for teapot, tulips, and truck.” The final page shows all of the animals playing together.
Who Says That, Cat The Cat?, Liz Kazandzhy
Who Says That, Cat The Cat?, Liz Kazandzhy
Children's Book and Media Review
Energetic and spunky Cat the Cat visits his many animal friends and asks them what sounds they make. Hound, Chick, and Cow happily make their sounds for Cat, but Bunny finds that he has no sound to make! But no worries—Cat and friends gather around to give him a hug so he doesn’t feel so bad.
My Dog Is The Best, Liz Kazandzhy
My Dog Is The Best, Liz Kazandzhy
Children's Book and Media Review
My Dog Is the Best is a short picture book that illustrates the bond between a boy and his dog. Despite the dog being intent on sleeping, the little boy enthusiastically finds plenty of activities to participate in with his canine friend and gives several reasons why his dog is truly the best.
Marty And Grace #4: Mutation, Tessa Mcmillan
Marty And Grace #4: Mutation, Tessa Mcmillan
Children's Book and Media Review
After Grace and the dinosaur hatchlings are rescued from Noah Blackwood, Wolfe and Ted take Marty, Grace, Luther, and Dylan to Brazil to aid in the search for Marty’s missing parents. The tweens and the two adults split into two traveling parities as they head towards Dr. Lansa’s jaguar preserve. Before and after the two groups arrive, several members of the preserve disappear into the rainforest with no trace. Finally only Marty, Grace, Dylan, and the hatchlings are left behind. But the hatchlings, who imprinted on Luther, follow Luther’s trail with Marty, Grace, and Dylan close behind. Together, they find …
Magic School Bus Presents: The Rainforest, Liz Kazandzhy
Magic School Bus Presents: The Rainforest, Liz Kazandzhy
Children's Book and Media Review
Jump on the Magic School Bus and come explore the rainforest! Here you’ll find all sorts of trees, vines, and other plants, which are home to thousands of species of mesmerizing bugs and animals. You’ll also learn more about apes, monkeys, birds, frogs, tigers, and snakes, and why it’s so important to preserve the rainforests to keep these animals safe.
Magic School Bus Presents: Sea Creatures, Liz Kazandzhy
Magic School Bus Presents: Sea Creatures, Liz Kazandzhy
Children's Book and Media Review
Jump on the Magic School Bus and come explore sea creatures! Starting at the beach and then taking you further and further and deeper and deeper, this journey will introduce you to a vast and beautiful world of sea animals and plants. You’ll see fish and sharks, whales and dolphins, turtles and snakes, jellyfish and octopuses, seals and sea lions, and so much more. You’ll also find out who lives by the coral reefs, in the kept forest, and at the bottom of the sea.
Magic School Bus Presents: Polar Animals, Liz Kazandzhy
Magic School Bus Presents: Polar Animals, Liz Kazandzhy
Children's Book and Media Review
Jump on the Magic School Bus and come explore polar animals! The first stop is the Arctic, where you’ll see polar bears, artic foxes, whales, seals, walruses, artic birds, musk oxen, and so much more. Then, on the other side of the world in Antarctica, you’ll be greeted by vast colonies of penguins, flocks of other birds, huge whales, and plenty of sea creatures that can withstand the harsh Antarctic climate. Finally, you’ll learn how global warming is putting many magnificent animals at risk of becoming extinct.
Magic School Bus Presents: Insects, Liz Kazandzhy
Magic School Bus Presents: Insects, Liz Kazandzhy
Children's Book and Media Review
Jump on the Magic School Bus and come explore insects! Besides seeing beetles, butterflies, and bees up close and personal, you’ll fly with crickets, mosquitoes, and dragonflies, crawl around with ants and cockroaches, and discover the remarkable defensive tactics that help insects stay alive. The amount of bugs and details included in this book is very impressive, as every page highlights several insects at once.
Hot Diggity Dogs, Liz Kazandzhy
Hot Diggity Dogs, Liz Kazandzhy
Children's Book and Media Review
Kate and Lucie are no ordinary girls… nor ordinary dogs! After buying special necklaces at a thrift shop, they realize that they can transform into dogs together with just the clap of a high-five. The book begins with them exploring the city as dogs, ordering “Hot Diggity Dog” hot dogs as girls, then playing at the park as dogs again. Soon they discover that the hot dog stand owners’ dogs, Ketchup and Mustard, have gone missing, and they join the community in searching, transforming between being human and canine depending on what’s most convenient. Once Ketchup and Mustard are safely …
Frog And Toad Storybook Treasury, Liz Kazandzhy
Frog And Toad Storybook Treasury, Liz Kazandzhy
Children's Book and Media Review
All of Frog and Toad’s adventures are now found together in one volume. In this storybook treasury, friendly Frog and the more serious Toad find themselves in all sorts of interesting situations as they discover the world around them. Among other things, they search for a lost button, go swimming, plant a garden, learn how to be brave, eat ice cream, and fly a kite. The stories are simple, sweet, funny, and insightful and always highlight the special bond between Frog and Toad.
Dogs Are People, Too: A Collection Of Cartoons To Make Your Tail Wag, Liz Kazandzhy
Dogs Are People, Too: A Collection Of Cartoons To Make Your Tail Wag, Liz Kazandzhy
Children's Book and Media Review
Dave Coverly, the creator of the comic Speed Bump, has compiled this collection of hilarious dog-related single-panel cartoons. Each section pokes fun at different facets of canine life, and a few chapters highlight some fun facts and interesting historical stories about dogs. Also included are several recollections from the author’s own life about the dogs he has owned and loved.
Reduced Efficacy Of Anti-AΒ Immunotherapy In A Mouse Model Of Amyloid Deposition And Vascular Cognitive Impairment Comorbidity, Erica M. Weekman, Tiffany L. Sudduth, Carly N. Caverly, Timothy J. Kopper, Oliver W. Phillips, David K. Powell, Donna M. Wilcock
Reduced Efficacy Of Anti-AΒ Immunotherapy In A Mouse Model Of Amyloid Deposition And Vascular Cognitive Impairment Comorbidity, Erica M. Weekman, Tiffany L. Sudduth, Carly N. Caverly, Timothy J. Kopper, Oliver W. Phillips, David K. Powell, Donna M. Wilcock
Sanders-Brown Center on Aging Faculty Publications
Vascular cognitive impairment and dementia (VCID) is the second most common form of dementia behind Alzheimer's disease (AD). It is estimated that 40% of AD patients also have some form of VCID. One promising therapeutic for AD is anti-Aβ immunotherapy, which uses antibodies against Aβ to clear it from the brain. While successful in clearing Aβ and improving cognition in mice, anti-Aβ immunotherapy failed to reach primary cognitive outcomes in several different clinical trials. We hypothesized that one potential reason the anti-Aβ immunotherapy clinical trials were unsuccessful was due to this high percentage of VCID …
Stress-Induced Reinstatement Of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity In The Basolateral Amygdala, Stephanie K. Nygard, Nicholas J. Hourguettes, Gabe G. Sobczak, William A. Carlezon, Michael R. Bruchas
Stress-Induced Reinstatement Of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity In The Basolateral Amygdala, Stephanie K. Nygard, Nicholas J. Hourguettes, Gabe G. Sobczak, William A. Carlezon, Michael R. Bruchas
Open Access Publications
UNLABELLED: The dynorphin (DYN)/kappa-opioid receptor (KOR) system plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substances of abuse. Due to nicotine's high propensity for stress-induced relapse, we hypothesized that stress would induce reinstatement of nicotine seeking-like behavior in a KOR-dependent manner. Using a conditioned place preference (CPP) reinstatement procedure in mice, we show that both foot-shock stress and the pharmacological stressor yohimbine (2 mg/kg, i.p.) induce reinstatement of nicotine CPP in a norbinaltorphimine (norBNI, a KOR antagonist)-sensitive manner, indicating that KOR activity is necessary for stress-induced nicotine CPP reinstatement. After reinstatement testing, we visualized robust c-fos …
What's New? The Zoo!: A Zippy History Of Zoos
What's New? The Zoo!: A Zippy History Of Zoos
Children's Book and Media Review
Where did zoos come from? This book takes you on a journey through history, from the first zoo 4400 years ago in present-day Iraq, to zoos all around the world that expanded throughout the last several centuries until just recently. Little snippets of zoo history are presented with the year and place of the event as well as illustrations.
Oh So Brave Dragon
Children's Book and Media Review
When little dragon shows off his bravery by letting out a fearful roar, he ends up frightening himself as well. He starts asking his woodland creature friends if they’ve seen or heard the monster, and they band together to overcome the imagined monster… and their own fear.
If You Were A Dog
Children's Book and Media Review
If you were a dog, what kind of dog would you be? Would you howl at the moon? In just a few words, this book takes you through the interesting lives of dogs, cats, fish, birds, bugs, frogs, and even dinosaurs, complete with sound effects for each. It ends with the best sort of thing to be: a kid!
The Fly
Children's Book and Media Review
This poor housefly doesn’t seem to understand why nobody likes him. First, the boy in the story tries to swat him just for wanting some of his breakfast. Then, even animals can’t seem to get along with him—cows are annoyed with him, frogs try to eat him, and birds try to catch him. When the fly returns home for another meal, the boy yet again flaps his swatter with the hopes of swatting the poor fly.
Tau Phosphorylation At Alzheimer's Disease-Related Ser356 Contributes To Tau Stabilization When Par-1/Mark Activity Is Elevated., Kanae Ando, Mikiko Oka, Yosuke Ohtake, Motoki Hayashishita, Sawako Shimizu, Shin-Ichi Hisanaga, Koichi M. Iijima
Tau Phosphorylation At Alzheimer's Disease-Related Ser356 Contributes To Tau Stabilization When Par-1/Mark Activity Is Elevated., Kanae Ando, Mikiko Oka, Yosuke Ohtake, Motoki Hayashishita, Sawako Shimizu, Shin-Ichi Hisanaga, Koichi M. Iijima
Department of Neuroscience Faculty Papers
Abnormal phosphorylation of the microtubule-associated protein tau is observed in many neurodegenerative diseases, including Alzheimer's disease (AD). AD-related phosphorylation of two tau residues, Ser262 and Ser356, by PAR-1/MARK stabilizes tau in the initial phase of mismetabolism, leading to subsequent phosphorylation events, accumulation, and toxicity. However, the relative contribution of phosphorylation at each of these sites to tau stabilization has not yet been elucidated. In a Drosophila model of human tau toxicity, we found that tau was phosphorylated at Ser262, but not at Ser356, and that blocking Ser262 phosphorylation decreased total tau levels. By contrast, when PAR-1 was co-overexpressed with tau, …