Digital Commons Network^™

A Position Statement On Endovascular Models And Effectiveness Metrics For Mechanical Thrombectomy Navigation, On Behalf Of The Stakeholder Taskforce For Artificial Intelligence-Assisted Robotic Thrombectomy (Start), Harry Robertshaw, Anna Barnes, Phil Blakelock, Raphael Blanc, Robert Crossley, Rebecca Fahrig, Ameer E. Hassan, Benjamin Jackson, Lennart Karstensen

School of Medicine Publications

Although we are making progress in overcoming infectious diseases and cancer, one of the major medical challenges of the mid-21st century will be the increasing prevalence of stroke. Occlusions in large vessels are especially debilitating, yet effective treatment—needed within hours to achieve best outcomes—remains limited because of geographic accessibility. One solution for improving timely access to mechanical thrombectomy in geographically diverse populations is the widespread deployment of robotic surgical systems. Artificial intelligence assistance may enable the safe and effective upskilling of operators in this emerging therapeutic delivery approach. Our aim was to establish consensus frameworks for developing and validating artificial …

Participation, Danielle M. Pillet-Shore

Faculty Publications

What does it take to participate in direct, naturally occurring social interaction? Conversation analytic (CA) studies reveal that “participation”—who participates, when, and how—is dynamic and locally, multimodally achieved by the people involved. Particularly in social situations when people are concurrently accessible to one another’s naked senses (Goffman, 1964), co-participation is enabled and performed through embodied and vocal resources including talk, gaze, facial displays, body orientation/posture, proximity, and gestures (e.g., M. H. Goodwin, 1999; C. Goodwin & M. H. Goodwin, 2005; Pillet-Shore, 2010; Sidnell, 2009). Using a multimodal CA lens, this chapter illuminates how “participation” is achieved in real-time, naturally occurring …

Stability Of Salivary Microrna Measures Across An Ncaa Division I Football Season: Implications For Microrna As A Biomarker Of Concussion, Thomas R. Campbell, Martina Zamponi, Delaney Leathers, Julie Cavallario, Jessica C. Martinez, Peter A. Mollica

Rehabilitation Sciences Faculty Publications

Background

Clinicians often face challenges in concussion care due to a heavy reliance on subjective patient input. Recently, research has sought objective biomarkers, like salivary microRNAs, to improve concussion management. However, significant limitations hinder the use of microRNAs as a diagnostic tool, including the cumulative effects of a contact sport season. A better understanding of the response to a contact sport season would help researchers and clinicians interpret expression changes at the time of injury in the context of seasonal variation. in Therefore, this study investigated the reliability of previously identified salivary microRNA targets across one contact sport season.

Methods …

Eeg And Imu Gait Signal Processing: A Comparative Assessment Of The "Reza" Exponential Filter And Classic Filters, Reza Pousti, Daniel M. Russell, Derek C. Monroe, Christopher K. Rhea

Rehabilitation Sciences Faculty Publications

Noise degrades both EEG and gait signals, and classical IIR filters (Butterworth, Chebyshev, elliptic) involve trade-offs between passband flatness, ripple, and roll-off. This study compared a novel exponential "Reza" filter with these designs for neural and locomotor data. We analyzed an open-source mobile brain-body imaging dataset with EEG and gait data from 49 healthy adults (EEG: 256-channel, 512 Hz; IMUs: six APDM Opals, 128 Hz). EEG channels were grand-averaged and band-pass filtered at 0.5-50 Hz, while IMU axes were averaged and band-pass filtered at 0.5-5 Hz. The outcomes were signal-to-noise ratio SNR (dB) and band-integrated Welch PSD (EEG:0.5-50 Hz; IMU:0.5-5 …

The Sequence (S) Index As A Marker Of Diminished Step-To-Step Transition Efficiency In Older Adults, Elham Alijanpour, Ashwini Kulkarni, Peter G. Adamczyk, Daniel M. Russell

Rehabilitation Sciences Faculty Publications

Introduction: Age-related declines in walking efficiency are often attributed to musculoskeletal and neuromuscular changes, yet the mechanisms underlying these inefficiencies remain poorly understood. One key contributor is the step-to-step transition (STST), during which the center of mass (CoM) is redirected between limbs. The Sequence (S) index quantifies the temporal overlap between push-off and collision forces during STST, with higher values indicating greater mechanical energy loss. This study investigated whether aging affects STST efficiency, as quantified by the S index, and examined the timing and impulse characteristics underlying observed differences.

Methods: Thirteen young and eleven older healthy adults walked at five …

Ultrasound-Based Assessment Of Talar Cartilage In Individuals With Chronic Ankle Instability: A Systematic Review, Amin Mohammadi, Saeed Eshghi, Iman Mohammadi, Patrick Wilson, Ryan Mccann

Rehabilitation Sciences Faculty Publications

Purpose

To systematically synthesize ultrasound (US) evidence on talar cartilage morphology and load-induced deformation in individuals with chronic ankle instability (CAI), and to map methodological approaches (acquisition, outcome definitions, loading paradigms, and normalization) to inform protocol standardization.

Methods

PubMed, Web of Science, and EBSCO were searched (March 31, 2025). Eligible studies reported quantitative US-derived talar cartilage morphology (e.g., thickness, cross-sectional area [CSA]) and/or deformation following standardized loading in CAI and comparison groups. Due to heterogeneity in imaging protocols, loading tasks, and outcome definitions, findings were synthesized narratively and organized by outcome domain.

Results

Across available cohorts, load-induced deformation was the …

Nonlinear Differences In Postural Sway Across Attentional Focus Conditions In Individuals With And Without Anterior Cruciate Ligament Reconstruction, Natalie L. Ferguson, Brian L. Cone, Christopher K. Rhea, Anne Beethe, Breanna Studenka

Rehabilitation Sciences Faculty Publications

BACKGROUND: The structure of variability in postural sway reflects the adaptability and health of the postural control system. Entropy quantifies this structure by measuring the regularity of repeated fluctuations over time. Although entropy has been used to examine sway in neurological populations, little is known about how sway complexity changes following anterior cruciate ligament reconstruction (ACLR). Attentional focus may also influence postural control, with external focus typically promoting more efficient and automatic regulation than internal focus.

AIM: To examine how attentional focus (internal vs. external) influences the structure of postural sway in individuals with and without ACLR.

METHODS: Forty-three participants …

A Narrative Review Of Bertolotti's Syndrome: Etiology, Classification, Diagnosis, And Treatment, Matyas Abel Tsegaye, Andrea Muffly

Rehabilitation Sciences Faculty Publications

Bertolotti's syndrome is a congenital condition characterized by chronic low back pain stemming from a lumbosacral transitional vertebra (LSTV). Because the condition is frequently overlooked, patients often face years of delayed diagnosis before the true source of their pain is identified. Furthermore, current information regarding the biological origins and clinical management of the condition remain scattered. To address this knowledge gap, this narrative review aims to provide a comprehensive overview of Bertolotti’s syndrome by consolidating these disparate sources and suggesting new connections. We synthesize the latest understanding of this condition, ranging from its genetic origins to modern clinical management. We …

We-Making Through Technology: Social Cohesion And Virtual Adaptation In Community Arts Organizations For Artists With Idd During Covid-19 Pandemic, Yumi Shirai, Michelle Boulanger Thompson, Tamara Shetron

Rehabilitation Sciences Faculty Publications

COVID-19 public health restrictions disrupted in-person arts participation, increasing risks of social isolation and reduced community access. Prior research shows that many people engaged in home-based arts and cultural activities during lockdown, supporting emotional regulation, a sense of belonging, and social connection; however, little is known about how these shifts affected community arts organizations that serve artists with intellectual and/or developmental disabilities (IDD), a population disproportionately impacted by the pandemic and longstanding inequities. We examined how community-based arts organizations adapted programming for artists with IDD during the COVID-19 pandemic, including barriers and unanticipated outcomes relevant to equitable access and participation …

Eeg Signatures Of Motor Development In Early Childhood: A Systematic Review, Sonia Khurana, Ashwini Kulkarni, Thomas C. Bulea, Hunter J. Bennett

Rehabilitation Sciences Faculty Publications

Background

Early identification of motor developmental disorders is limited due to lack of objective neural markers that characterize typical neurodevelopmental patterns. This systematic review interprets and synthesizes existing evidence to propose a framework of EEG signatures associated with motor development in children aged 0-5 years, which may help inform future benchmarks for early assessment and intervention.

Methods

Following PRISMA guidelines, we searched published and gray literature across five databases between 2000 and 2025 (registered protocol). Included studies examined EEG during task-based, resting-state, or sleep studies linked to motor milestones, task performance, or standardized motor assessments. Study quality was assessed using …

The Epidemiology Of Catastrophic Head And Neck Injuries In High School And College Non-Football Sports: A 4-Decade Review, Courtney M. Meyer, Kristen L. Kucera, Samantha E. Scarneo-Miller, Zachary K. Winkelmann, Susan W. Yeargin

Rehabilitation Sciences Faculty Publications

Background:

Catastrophic head and neck injuries (CHNIs) in sport are rare but can have disabling or fatal outcomes. Prior studies have focused on football, equipment-laden sports, or different injury severities, not CHNI in nonfootball sports.

Purpose:

To describe the epidemiology of CHNI across levels (high school vs collegiate) in nonfootball sports and evaluate differences in injury rates (IRs) by sport, sex, and decade.

Study Design

Descriptive epidemiological study.

Methods:

This study utilized 40 academic years (1982-1983 to 2021-2022) of surveillance data from the National Center for Catastrophic Sports Injury Research. Descriptive statistics summarized athlete, event, and injury characteristics. IRs were …

Walking It Off: Habituation Of Gait At Virtual High Elevation, Kelly Poretti, Toby J. Ellmers, Christopher K. Rhea, Tiphanie Raffegeau

Rehabilitation Sciences Faculty Publications

Introduction: Fear and anxiety about falling can disrupt gait control, leading to activity restriction and increased fall risk in older adults. VR can be used to induce postural threat (e.g., by simulating high elevation settings) within a controlled environment, inducing fall-related anxiety and cautious gait (i.e. slower, shorter steps) in young and older adults. However, it is unknown how emotional and motor responses to VR postural threat habituate across time because existing studies feature short exposures (10 seconds or less). Before VR-induced postural threat can be translated into an intervention, it is critical to understand threat-related gait habituation across time. …

Organized Sports-Based Interventions And Motor Outcomes In Children Diagnosed With Autism Spectrum Disorder: A Systematic Review, Kailash Ram, Maeren Hill, Caitlyn Stewart, Kaitlin P. Hardy Md, Sonia Khurana

Rehabilitation Sciences Faculty Publications

Aim

To evaluate the effectiveness of organized sports-based interventions on motor outcomes in children with autism spectrum disorder (ASD).

Method

Four databases were searched from inception to November 2025 for randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) reporting motor outcomes of organized sports-based interventions in children with ASD. Risk of bias was evaluated using ROB-2 (Cochrane Risk of Bias Tool, Version Two) for RCTs and ROBINS-I (Risk Of Bias In Non-randomized Studies - of Interventions) for NRCTs.

Results

Eleven studies (six RCTs, five NRCTs) were included and categorized as martial arts (n = 5), aquatic training (n = …

Patch-Moe Mamba: A Patch-Ordered Mixture-Of-Experts State Space Architecture For Medical Image Segmentation, Diego Adame, Fabian Vazquez Jr., Jose A. Nunez, Huimin Li, Jinghao Yang, Erik Enriquez, Dongchul Kim, Haoteng Tang, Bin Fu, Pengfei Gu

Computer Science Faculty Publications

CNN- and Transformer-based architectures have achieved strong performance in medical image segmentation, but CNNs are limited in modeling long-range dependencies, while Transformers often suffer from quadratic computational and memory complexity. State space models, especially Mamba-based networks, offer an efficient alternative with linear sequence complexity. However, existing Mamba segmentation models still face two limitations: pixel-wise directional scanning can disrupt local 2D spatial structure, and simple summation-based fusion of scan directions cannot adapt well to diverse object sizes, shapes, and boundaries. To address these issues, we propose Patch-MoE Mamba, a patch-ordered mixture-of-experts state space architecture for medical image segmentation. It introduces a …

The Write Routine: A Practical User-Friendly Guide On How To Incorporate A Writing Routine Without The Use Of Digital Assistance In The Secondary Classroom, Marie Roark

Education | Graduate Culminating Projects

The purpose of this project is to design a non-digital Instructional Teacher’s Guide that supports equitable literacy outcomes for all secondary students. By synthesizing Universal Design for Learning (UDL) and Cognitive Load Theory (CLT), this digital-free model removes screen-based distractions to minimize unnecessary cognitive load, directly benefiting students with executive functioning deficits and language acquisition needs. Secondary content-area assignments will be redesigned to integrate The Write Routine, a frequent, mico-writing task using a 5 minute writing prompt, converting abstract composition into manageable, daily writing benchmarks that build working memory, organizational skills, and greater confidence in independent writing capabilities.

Guidelines For Standard Basic Notations In Applied Statistics, Abhaya Indrayan, Shivani Saini Ms

COBRA Preprint Series

Whereas some statistical notations are standard and uniformly used by different workers, many are not. Varying notations lead to confusion among the readers, particularly those engaged with applied statistics material, such as medical professionals. This communication proposes that all basic notations be standardized so that the same notations are consistently used by different authors, in different books, journals, and articles for the benefit of those who are not rigorously trained statisticians. Guidelines for such standard notations are also provided. The lead must be taken by statisticians.

Campbell At 30: A Retrospective Appreciation, Michael W. Carroll, Peter Jaszi

Scholarly Articles in Law Reviews & Journals

This Article traces the intellectual history of copyright law’s fair use doctrine at the Supreme Court from its first encounter with fair use to its landmark decision slightly more than three decades ago in Campbell v. Acuff-Rose Music, Inc. Campbell provided courts with a coherent, user-centered theory for applying the four statutory fair use factors provided under 17 U.S.C. § 107, a standard the Court recently ratified in Google LLC v. Oracle Am., Inc. and Andy Warhol Foundation for the Visual Arts v. Goldsmith. As one of three related articles, this Article advances two principal claims to contribute to …

Lunch Shaming And The Right To Privacy, Ira P. Robbins

Scholarly Articles in Law Reviews & Journals

Lunch shaming is the practice of penalizing students who cannot afford to pay for their meals, resulting in them being denied food, served alternative meals, or publicly identified. The origins of lunch shaming can be traced to the financial pressures faced by school districts that struggle to balance tight budgets with the mandate to provide free or reduced-price meals to eligible students. Despite legislative efforts and advocacy campaigns aimed at mitigating the problems associated with lunch shaming, the practice persists, exacerbated by rising food costs and the expiration of pandemic-era food programs.

Many law journal and other articles have correctly …

Originalism As Disruption, Susan D. Carle

Scholarly Articles in Law Reviews & Journals

This Article challenges the conventional understanding of originalism as a method that promotes unchanging constitutional meanings. Drawing on four and a half decades of experience since Attorney General Edwin Meese first championed originalism as a conservative project, this Article demonstrates that originalism has generally proven destabilizing rather than stabilizing to constitutional law. Landmark cases such as New York State Rifle & Pistol Association v. Bruen, Students for Fair Admissions, Inc. v. President & Fellows of Harvard College, and Shelby County v. Holder show that the Supreme Court frequently deploys originalism when it seeks to upend settled constitutional doctrine, contradicting claims …

Law’S Limits: Abortion And The Social Determinants Of Health, Maya Manian

Scholarly Articles in Law Reviews & Journals

After Dobbs: How the Supreme Court Ended Roe but Not Abortion (“After Dobbs”) is a prescient and timely response to the U.S. Supreme Court’s 2022 decision in Dobbs v. Jackson Women’s Health Organization, which overturned Roe v. Wade and upended nearly five decades of constitutional protection for abortion. In this meticulously structured oral history, law professor David S. Cohen and sociologist Carole Joffe center the voices of abortion providers, clinic administrators, funders, and advocates from across the country. After Dobbs, not only documents the extraordinary persistence of abortion supporters in the face of legal devastation but also bears witness to …

Myopiax-1 Safety And Efficacy Of A Novel Approach To Slow Juvenile Myopia Progression: A Multicenter, Randomized, Controlled Trial, Myopiax-1 Study Group, James Loughman, Gareth Lingham, Hakan Kaymak, Katrin Lorenz, Jan Roelof Polling, Anna Beck, Gonzalo Carracedo, Annegret H. Dahlmann-Noor, Philipp L. Müller, Ian Flitcroft

Research Outputs: 2025-Present

Purpose: To investigate the safety, tolerability, and signals of effect of MyopiaX, a smartphone app that selectively delivers blue light to the optic nerve head to control myopia progression in children and adolescents. Design: Multicenter, randomized, active-controlled, examiner-masked proof-of-concept clinical trial (ClinicalTrials.gov identifier NCT04967287). Participants: Eligible children aged 6 to 12 years, with myopia of cycloplegic spherical equivalent refraction (SER) between –0.75 and –5.00 diopters (D) at baseline. Children were screened and enrolled between November 2021 and September 2023. Methods: Children were randomly assigned in a 2:1 ratio to MyopiaX or active control. Participants were instructed to use MyopiaX for …

Readability Of Online Patient Education Materials For Myopia Management, Monica Jong, Michelle Waugh, Pinar Ozmizrak, Ian Flitcroft

Research Outputs: 2025-Present

Purpose: Patients are turning to the internet to access educational materials to help them make healthcare decisions, making readability an important factor. This cross-sectional study assessed the readability of online patient education materials for myopia management treatments that have regulatory approval. Methods: The top 10 Google search results from May 2024 for freely available online patient information on myopia management modalities and regulatory-approved products in Canada and Australia were analysed for readability. The modalities included orthokeratology, myopia control spectacle lenses, myopia control soft contact lenses and atropine. The products included MiYOSMART® [HOYA®], Stellest® [Essilor®], MyoCare® [ZEISS], MiSight® 1 day [CooperVision®], …

E-Profits: A Business-Aligned Evaluation Metric For Profit-Sensitive Customer Churn Prediction, Awais Manzoor, M. Atif Qureshi, Etain Kidney, Luca Longo

Research Outputs: 2025-Present

Retention campaigns in customer relationship management often rely on churn prediction models evaluated using traditional metrics such as AUC and F1-score. However, these metrics fail to reflect financial outcomes and may mislead strategic decisions. We introduce e-Profits, a novel business-aligned evaluation metric that quantifies model performance based on customer lifetime value, retention probability, and intervention costs. Unlike existing profit-based metrics such as Expected Maximum Profit, which assume fixed population-level parameters, e-Profits uses Kaplan–Meier survival analysis to estimate tenure-conditioned (customer-level) one-period retention probabilities and supports granular, per-customer profit evaluation. We benchmark six classifiers across two telecom datasets (IBM Telco and Maven …

Are Ocular Markers Of Sun Exposure Associated With Skin Cancer? A Cross-Sectional Analysis Of The Busselton Healthy Ageing Study, Gareth Lingham, Vinay Kumar Nilagiri, Holly Brown, Chrianna Bharat, Samantha S.Y. Lee, Maria Franchina, Michael Hunter, Kevin Murray, David Alonso-Caneiro, Catherine M. Olsen, David C. Whiteman, David A. Mackey

Research Outputs: 2025-Present

Background: Higher past sun or ultraviolet radiation exposure increases the risk of skin cancer and three common ocular findings: pterygium, conjunctival ultraviolet autofluorescence (CUVAF) and myopia. We investigated whether ocular markers of past sun exposure are associated with a history of skin cancer. Methods: A cross-sectional study of participants who attended the Phase 2 examination of the Busselton Healthy Ageing Study in Western Australia (2016–2022). Myopia was determined from autorefraction and pterygium and CUVAF from photographs of the anterior eye. Past diagnosis of a skin cancer was obtained from linked hospitalisation and cancer registry data (melanoma) or combining linked and …

Exploring Characteristics And Systemic Health Links In Myopic Australian Adults, Pauline Kang, Gareth Lingham, Angelica Ly, Xianwen Shang, Regan Ashby, Serge Resnikoff, Fiona Stapleton, David Mackey

Research Outputs: 2025-Present

Background: Data on myopia prevalence in Australia and associations with common systemic conditions and quality of life are limited. This study aimed to profile Australian adults self-reporting to have myopia, including co-morbidities and quality of life. Methods: This research included participants from the ongoing longitudinal 45 and Up Study. Sex and education data were collected at the baseline survey and additional data from the follow-up Health Compass survey. Responses on self-reported myopia, health and quality of life were analysed with logistic regression to assess the association between myopia and health conditions. Results: Of the 21,384 participant responses, 54.3% self-reported myopia, …

How Low Can We Go? Quantization Effects On Llm Sparql Generation, Matt Murtagh-White, P. J. Wall, Declan O’Sullivan

Research Outputs: 2025-Present

SPARQL is a powerful but complex language for querying knowledge graphs, motivating research into natural language-to-SPARQL generation using large language models (LLMs). While large, proprietary LLMs excel at this task, their resource requirements can limit practical deployment. This paper evaluates smaller, open-source LLMs (0.5B–9B parameters) with quantization methods (8-bit and 4-bit compression) to balance computational efficiency and query generation performance. Our findings demonstrate that 8-bit quantization can maintain or enhance performance in smaller models, whereas 4-bit quantization leads to notable degradation, especially for larger models. This highlights the potential of quantized, smaller LLMs for SPARQL generation in resource-constrained scenarios and …

A Review Of Data Interoperability As A Barrier To Non-Residential Building Energy Policy: Evidence From Ireland, Ankur Mitra, Kriti Bhalla, Ciara Ahern

Research Outputs: 2025-Present

Non-residential buildings account for a significant share of energy use and greenhouse gas emissions across the EU, yet evidence-based policy development remains hindered by fragmented and non-interoperable building data systems. This study evaluates the suitability of publicly available electronic datasets for characterising Ireland’s non-residential building stock and supporting bottom-up energy modelling in the context of the recast Energy Performance of Buildings Directive (EPBD 2024/1275/EU).A systematic scoping review of national government and institutional datasets was conducted using an adapted PRISMA-ScR approach. The analysis identified the national Energy Performance Certificate database and GeoDirectory as the only datasets with sufficient scale and detail …

Shap-Rc: A Framework For Explaining Annotator Disagreement In Sexism Detection, Madhuri Sawant, Arjumand Younus, Simon Caton, M. Atif Qureshi

Research Outputs: 2025-Present

The effectiveness of supervised machine learning models is heavily influenced by the quality of training data, which is often shaped by human annotators. Subjective NLP tasks such as hate speech detection, toxicity identification, and sexism classification frequently exhibit annotator disagreement due to differences in individual perspectives. This study investigates annotator disagreement in sexism detection using English tweets from the EXIST 2023 competition. To systematically analyse disagreement, tweets are categorised based on annotator consensus levels, examining how annotator demographics and linguistic features contribute to labelling inconsistencies. We interpret disagreement patterns using Shapley Additive Explanations (SHAP) and assess the consistency of SHAP-derived …

Modeling The Proton Irradiation Resilience Of Perovskite Solar Cells, Ming Lang Tseng, Emad A.A. Ismail, Nima Ghadiri, Fuad A. Awwad

Research Outputs: 2025-Present

This study introduces a semiclassical modeling for the impact of proton irradiation on two perovskite solar cell structures: FA_0.7Cs_0.3Pb(I_0.9Br_0.1)₃/C₆₀ and Cs_0.01MA_0.01FA_0.98PbI₃/P3HT using coupled current-continuity and rate equations linked to irradiation-induced defect-generation rate. Results reveal a strong dependence of radiation response on perovskite composition. Proton irradiation can induce both ionizing and displacement damage in perovskite solar cells leading to vacancy and defect generation. The result is increased recombination and degradation of performance parameters (reduced fill factor and efficiency) or, otherwise, annihilation of …

Sustainable Closed-Loop Supply Chain Network Design Under Uncertainty Using A Fuzzy Multi-Objective Optimization Framework For The Battery Industry, Mahdi Yousefi Nejad Attari, Sahar Rezanejad, Ali Ala, Vladimir Simic, Dragan Pamucar

Research Outputs: 2025-Present

The study presents a sustainable closed-loop supply chain network that integrates financial, environmental, and social objectives within a context of uncertainty. A fuzzy-based modeling approach is introduced to address uncertainty in customer demand, cost parameters, and carbon emission coefficients across the sustainable closed-loop supply chain network. Two metaheuristic methods, the non-dominated sorting genetic algorithm II (NSGA-II) and multi-objective particle swarm optimization (MOPSO), are employed to address the problem and are compared against each other. A practical case study of a battery company is employed to validate the framework. The findings indicate that MOPSO surpasses non-dominated sorting genetic algorithm II in …