Digital Commons Network^™

Definitions Of Arginine Availability: A Critical Metabolic Marker Of Physiological Processes, Mustafa Tosur, Farook Jahoor, Ashok Balasubramanyam

Faculty, Staff and Students Publications

No abstract provided.

The Development And Initial Validation Of A Measure Of Professional Mentoring Engagement Among School Counselors, Emily Kitching

Theses and Dissertations

This study describes the development and initial validation of the Mentoring Engagement Scale (MES), a self-report instrument designed to measure a person’s level of engagement in professional mentoring. Despite emerging evidence that professional mentoring may serve as a protective factor against the burnout and stress associated with school counselors’ roles and responsibilities, existing measures of mentoring are limited by weak documentation of development procedures, mixed psychometric support, and limited practical applicability. In two phases, the present study aimed to (1) evaluate content validity and systematically refine items grounded in Kahn’s (1990) theory of engagement and (2) investigate the preliminary psychometric …

Examining The Impact Of Trauma-Informed Mindfulness Meditation On Posttraumatic Growth Following Interpersonal Trauma: A Randomized Controlled Trial, Margaret Poandl

Theses and Dissertations

Research on interventions designed to increase posttraumatic growth (PTG) among interpersonal trauma survivors is limited. The purpose of this study was to examine the impact of a six-week trauma-informed mindfulness meditation intervention on PTG. Additionally, I examined outcomes of posttraumatic stress (PTS) and loneliness, as well as analyzed the variables of dispositional mindfulness, hope, spirituality, and self-compassion to understand their potential role as mechanisms of change within the intervention on PTG. To answer these research questions, I conducted a randomized controlled trial study with 113 adults from a community sample who reported experiencing interpersonal trauma. Utilizing linear mixed modeling and …

Conceptual Concerns Regarding The Content Validity Of The Construct Of Gender Dysphoria In The Diagnostic And Statistical Manual Of Mental Disorders, Fifth Edition, Text Revision, Waverley Vesely

Theses and Dissertations

The diagnostic classification of gender dysphoria in the DSM-5-TR elicits a number of clinical, political, and philosophical concerns, ranging from those that are diagnostic and taxonomical in nature to those that fall within the domains of ontology, phenomenology, and hermeneutics. Part of the reason for the complexity of studying the diagnostic and nosological validity of gender dysphoria as an extant diagnostic classification is that, unlike many disorders, gender dysphoria is inextricably tethered to identity. While the recent change from gender identity disorder to gender dysphoria has nominally removed the status of disorder, in practice, both clinicians and the general population …

Foreign-National Families, Education, And Parenting: Unpacking The Influence Of Cultural Transitions On Child-Rearing And Expectations, Yuqi Zhang

Theses and Dissertations

This qualitative study examines how highly skilled foreign-national parents navigate parenting and educational decision-making within the context of cultural transition in the United States. While existing research on foreign-national parenting has largely focused on socioeconomically disadvantaged populations, less is known about families who possess substantial educational and professional capital. Despite these advantages, these parents encounter unique challenges related to institutional navigation, identity negotiation, and social constraints. Guided by Bronfenbrenner’s bioecological theory, Coleman’s social capital theory, Berry’s acculturation framework, and Yosso’s community cultural wealth model, this study explores how cultural background and migration experiences shape highly skilled foreign-national families’ parenting beliefs …

Medical Linear Accelerator Water Tank Measurements Optimization For Commissioning, Tyler R. Laugh

Theses and Dissertations

Beam commissioning is a critical component of linear accelerator (LINAC) implementation, requiring accurate measurement of percent depth dose (PDD), beam profiles, and output factors across a wide range of field sizes. Conventional commissioning workflows often require multiple detectors and can be time-intensive, particularly for small-field dosimetry where measurement accuracy is highly sensitive to detector characteristics. This study evaluated the performance of a plastic scintillation detector (BP-PSD) for full water tank commissioning and its potential to improve efficiency while maintaining dosimetric accuracy.

Beam data were acquired for field sizes ranging from 1 × 1 cm² to 40 × 40 cm² using …

Commissioning & Daily Qa Of Converted Linac For Electron Flash, Tomaj Javidtash

Theses and Dissertations

Ultra-high dose rate (FLASH) radiotherapy has demonstrated promising normal tissue sparing in preclinical studies; however, the lack of standardized dosimetry, commissioning, and quality assurance (QA) methodologies remains a major barrier to its reproducible and safe implementation. In particular, conventional clinical commissioning and QA protocols are not directly applicable at FLASH dose rates due to challenges associated with detector response, dose-per-pulse effects, and beam control limitations.

This thesis presents the commissioning of a converted Varian 21EX linear accelerator for electron FLASH operation within the Division of Medical Physics at the Virginia Commonwealth University (VCU) Department of Radiation Oncology. Comprehensive beam characterization …

Psychometric Evaluation Of The Treatment Integrity Instrument For Elementary School Classrooms - Observer Report: Preliminary Evidence For Construct And Discriminative Validity, Cristian J. Rivera Nales

Theses and Dissertations

Treatment integrity is the degree to which a program and its practices are delivered as intended. Treatment integrity measures are critical for evaluating the effectiveness of evidence-based programs (EBPs) in effectiveness research, but few are designed for research conducted in community settings, such as schools. The Treatment Integrity Instrument for Elementary School Classrooms – Observer Report (TIES-O) is an observational measure used to assess the treatment integrity of teachers implementing EBPs in their classrooms. This study evaluated the psychometric properties of the TIES-O, which captures Adherence (frequency and thoroughness of delivery) Competence (skillfulness of delivery), and Differentiation (the extent to …

Staging Violence With Intentionality, Toby O'Brien

Theses and Dissertations

This thesis examines the role of the fight choreographer in the theatre while addressing the potential issues staged violence has in distracting an audience from the intended narrative of the play. Avoiding the instruction manual approach of stage combat in favor of expounding on the theory of violent entertainment, I have constructed a thesis that informs the reader of certain types of violence found in both classical and modern productions and have researched the psychological ramifications of violent spectatorship and the necessity for content acknowledgements as well as consideration for the performer’s well-being. By exploring the history of violent entertainment …

Follow The Cyclists: Everyday Navigation Of Richmond's Bike Infrastructure, Emily E. Schreer

Theses and Dissertations

This thesis explores the embodied experience of cycling in Richmond, emphasizing the importance of centering firsthand, lived experience in cycling research and urban planning. While traditional transportation planning can often myopically prioritize efficiency and safety metrics to evaluate infrastructure, this project argues that such approaches overlook essential experiential, sensory, and emotional dimensions of cycling that determine how infrastructure is perceived, used, and ultimately succeeds or fails.

Through an ethnographic approach combining field observation of cyclist behavior and mental mapping sessions with Richmond cyclists, this study positions people who bike in Richmond as expert knowledge holders. Participant contributions, combined with observations …

Towards Sample-Efficient Deep Reinforcement Learning, Guang Yang

Theses and Dissertations

Deep reinforcement learning (DRL), combining reinforcement learning and high-performance function approximations such as deep neural networks (DNN), is a powerful approach to solving complex sequential decision-making problems. However, due to the complex solution space of the sequential decision-making problems and the inefficient design of the DRL algorithms, DRL algorithms usually require a prohibitively large number of data samples to train effective strategies. Consequently, it is difficult to apply these DRL algorithms to complex real-world problems that require high costs to collect a large volume of data samples. This dissertation proposes new mechanisms to address this sample inefficiency issue, realizing sample-efficient …

An Integrated Data-Driven Framework For Arctic Shipping: Analyzing Vessel Speed, Environmental And Ecological Factors Through Innovative Statistical Spatio-Temporal Methods, Inverse Optimization And Machine Learning, Mauli Pant

Theses and Dissertations

This dissertation develops an integrated data-driven framework to analyze vessel navigation and ecological risk in the United States Arctic from 2010 to 2019. As environmental change and maritime activity increase in the region, understanding how vessels respond to dynamic conditions and how those responses interact with marine ecosystems has become increasingly important. A central theme of this dissertation is the treatment of vessel speed as both an observed outcome and a decision variable reflecting trade- offs among operational, environmental, and ecological factors. The first chapter develops a predictive framework for vessel speed over ground (SOG) using Gaussian Process Boosting (GPBoost), …

Magnetic Resonance Only Planning Validation Using Synthetic Ct By Mvision, Eric D. Brass Sr

Theses and Dissertations

Problems: Adaptive radiotherapy requires clinically practical methods for responding to patient-anatomy changes that occur between the original planning images and the day of treatment delivery. Registering a previously acquired computed tomography scan to a newly acquired magnetic resonance image can introduce cross-modality uncertainty and may delay replanning. This thesis evaluates whether synthetic computed tomography generated from same-day magnetic resonance imaging can reduce registration-related uncertainty while supporting rapid dose recalculation for fraction-level adaptation.

Procedure: Magnetic resonance imaging DICOM data were exported from the ViewRay MRIdian treatment planning system and uploaded to MVision for synthetic computed tomography generation. The synthetic computed tomography …

Restructuring Actor Training For Psychological Wellbeing, Caroline C. Byce

Theses and Dissertations

This thesis highlights the importance of performer mental health as it relates to performance pedagogy. Based on a comprehensive review of traditional western actor training methods, survey data, and interviews, this research proposes a framework through which educators, directors, and performers alike can acknowledge both the artistic value and psychological harm prevalent in many prominent acting techniques. The insights put forth by this thesis extend beyond theatre acting and into television and film acting respectively, culminating in a series of practical steps -transferrable to any medium - for implementing a restructured and more human-centered approach to classrooms, workshops, and rehearsal …

The Ethereal Being That Is Me, And Maybe You, Hwiy Chang

Theses and Dissertations

The Ethereal Being That Is Me, and Maybe You is a 23-minute video collection of short stories accompanied by an installation at the Institute for Contemporary Art at Virginia Commonwealth University. This thesis explores the work’s creation as a visual and narrative meditation on self-transformation, drawing from personal experiences in therapy and philosophical texts including Carl Jung’s concept of the unconscious. The paper examines how each story represents a distinct stage of transformation—from recognizing patterns to confronting setbacks to reshaping internal dialogue—and how watercolor’s fluid, unpredictable nature serves as a visual metaphor for the process of change. The installation component …

A Mutant Perfect, Amelia R. Baxter

Theses and Dissertations

A Mutant Perfect examines how embodied knowledge can be made visible and transmissible through ceramic figures. The research asks what forms emerge when making is understood as a mode of thinking rather than a vehicle for pre-formed ideas, and how those forms might activate somatic recognition in a viewer. The primary method is coil-built ceramic sculpture. Color is applied in layered coats and removed by hand-sanding to expose varying strata beneath, producing a speckled, worn surface. In a second approach, pigment is built directly into the clay body through coil construction, making color structural rather than applied. Narrative prose and …

My Mouth Is A Glutton, My Mouth Is A Lover., Cole Kamerick Eller

Theses and Dissertations

This thesis is a reflection on my relationship with jewelry. I discuss the impact of jewelry

and its materials. What are the ramifications of these objects? Politically, socially, and

spiritually. I reflect on material agency, cultural unconscious, and value systems, and

how I relate to jewelry, my love for it, and my grief for it. This work is the result of ritual

and impulse. The writing is my reflection on the results of that ritual.

Daisyworld, Eva Foldy

Theses and Dissertations

Daisyworld explores how painting can represent ecological and sociopolitical crisis without relying on narratives of total collapse as a catastrophic end, instead framing the present as a condition of ongoing, uneven transformation. Drawing on ecological models of adaptation, interdependence, and planetary self-regulation, it uses plant fasciation as both a biological reference and speculative metaphor for distorted yet generative forms of survival. Situating painting within a broader history of visual culture, it examines how images function as accessible systems of knowledge while challenging colonial and human-centered modes of representation. In dialogue with contemporary, systems-based artistic practices, the project repositions painting as …

Absolute Quantification And Identification Of Rna From Rna-Lipid Nanoparticles Using High Resolution Mass Spectrometry, Jason C. Funderburk

Theses and Dissertations

RNA therapeutics are a rising drug category with potential use for a range of conditions encompassing infectious diseases to therapies for cancer, diseases, and genetic disorders. RNA-lipid nanoparticles (RNA-LNPs) are the prominent delivery method for these therapeutics approved products include mRNA vaccines and polyneuropathy treatments. The emergency use authorizations and orphan drug status of current RNA-LNP drugs has allowed approval without finalization of the regulatory analytical procedures for quality monitoring. The objective of the study was to develop an LC-MS assay to simultaneously measure identity and concentration of two therapeutically relevant intact RNA constructs extracted from RNA-LNPs to enhance quality …

Light And Unseen, Daša Kulikova

Theses and Dissertations

This thesis is a body of paintings and two poetic fragments. Shaped by distance and displacement, the work finds its ground in the tension between the desire to be free from the past and heal, and longing for home and connection. Painting practice becomes an event of contact with what is lost, or unclear, or in the process of becoming through accumulating layers, marks, erasures, and traces of the process of its making.

Between The Veins: Materializing Memory In The Age Of Digital Storage, Alice Mohammed Aslem

Theses and Dissertations

What happens to a childhood stored behind a password? This thesis began with a simple moment of scrolling through my son’s photographs on my phone. As the images multiplied, they began to lose clarity, turning into an overwhelming digital archive. This made me ask: What kind of memories am I preserving for him?

Having grown up between analog and digital worlds, Between the Veins explores how I navigate memory through material objects and digital archives. Using weaving, images are transferred onto screw pine and palm leaves. In this process, digital files of his childhood are translated into organic fibers of …

Substance Use Behaviors And Treatment Engagement In Individuals With Severe Psychopathology With And Without Comorbid Obesity, Rachel M. Madera-Arnold

Theses and Dissertations

Research has found significantly higher rates of both substance use and obesity among individuals with SMI compared to population samples which in turn can lead to worsening health outcomes. Despite this, there is limited research on the co-occurrence of obesity, substance use, and SMI and how these conditions may interact to affect patient outcomes. In addition, there are many gaps in the research regarding the relationship between substance use and body weight, appetite and/or eating behaviors. This study conducted a secondary analysis of the NSDUH 2021 survey that characterized substance use and disorders among individuals who had severe psychopathology, examined …

Awareness, Empathy, Action: How American Students’ Study Abroad Experiences In The Middle East And North Africa (Mena) Influence Self-Perceptions Of Global Citizenship, Renee Lamb

Theses and Dissertations

Internationally minded practitioners and academics have posited for decades that global citizenship could be a tool the world can use to build a stronger and more sustainably minded global culture. Through global citizenship’s inclusion in the United Nations Sustainable Development Goals, Target 4: Quality Education, educators from pre-primary to university have been put at the forefront of this movement. At the higher education level, study abroad is arguably the most important global learning tool used by American institutions today for building global citizenship. However, the vast majority of American students study abroad in Western Europe, leaving a glaring gap in …

Algorhythm: Commodification Of Hobbies On Social Media Platforms, Fariha Ahmed

Theses and Dissertations

Forcing the world online, the COVID-19 pandemic appeared to turn social-media-based hobbies into income-generating cash cows. Digital creative spaces became sites of capitalist logic where hobbyists came to operate as both laborers and commodities. Profit-focused algorithms operate imperceptibly, shaping creative behavior and decision-making in ways that are difficult to recognize, and even harder to resist. This thesis asks how algorithmic participation on platforms such as Instagram conditions a hobbyist, and how that conditioning can be made legible to audiences who inhabit such platforms without always seeing them. Using autoethnography, I position myself as both researcher and subject to document the …

Will You Let Me In?, Irene Piazza

Theses and Dissertations

Imposed borders are everywhere: The borders created by stanchions during bureaucratic lines, the borders of a country, the borders of a page. Humans are forced to follow them. Borders are imposed structures that dictate a way to move, a way to write, a way to be confined. But what happens when those borders aren’t followed? What happens when someone decides to walk through the stanchion belt by crouching under it or sliding its buckle open? What happens if a person decides to walk outside of the paved pathway? What happens if someone crosses a border or writes beyond the page …

Within The Ruin: A Modern Brewery Rebirth, Karim Asarzadeh

Theses and Dissertations

This thesis project focuses on the revitalization of the historic ruins of the James River Steam Brewery in Richmond, Virginia. The project transforms the forgotten industrial structure into a modern brewery with a second-floor restaurant addition and community gathering spaces while preserving the historic masonry ruins. It showcases a holistic design approach that considers all aspects of the building, including its connection to the urban context and landscape, as well as its architecture, interiors, and furniture. The project demonstrates how a holistic design approach can create stronger spatial connections and more cohesive environments. In particular, it offers a strategy for …

Characterization Of Microrna Expression In Neuron-Enriched Extracellular Vesicles During Early Life, Allison Molen

Theses and Dissertations

Extracellular vesicles (EVs) are membrane-bound sacs released by cells that carry molecular cargo reflective of their cell of origin. EVs enriched using L1 cell adhesion molecule (L1CAM) as a marker of putative neuronal origin can cross the blood–brain barrier and provide a minimally invasive window into brain-related processes. Exosomal microRNA (miRNA) regulate gene expression and have been implicated in psychiatric disorders, including major depressive disorder (MDD). However, measuring and analyzing miRNA from L1CAM-positive EVs presents substantial analytical challenges due to low abundance and sparse detection across samples.

Plasma samples from participants recruited through the Mid-Atlantic Twin Registry (MATR) were used …

Spell Of Forty Small Failings, Erin B. Ehren

Theses and Dissertations

Spell of Forty Small Failings is a collection of images and writings that draws from an unruly range of literary forms, academic disciplines, and religious cannons in order to address the Divine—all that which exists on account of the phenomena of what it is to see and be seen: to hear and be heard: to touch and be touched: to know and be known, and through that knowing proceed beyond mediation. I wrote this thesis for me in the hopes that all along I was writing for you.

A Mathematical Frameworks For Singular, Nonlinear Phenomena: Applications To Nematocyst Firing And Inhomogeneous Nls With Coulomb Potential, Abdulrahman Alharbi

Theses and Dissertations

Nematocysts are specialized cellular organelles found in all cnidarians, including corals and jellyfish, as well as in some single-celled protists such as dinoflagellates. These organelles display remarkable diversity in morphology and function, playing roles in prey capture and defense. The firing of a nematocyst is one of the fastest accelerations in nature, yet the underlying physical mechanisms remain not fully understood. In this work, we address key questions: how sufficient force is generated to overcome the fluid boundary layer, whether fluid–structure interaction models can reproduce observed dynamics, and what mechanisms trigger discharge.

Our research investigates models based on osmotic pressure …

Mediator: Ornament As A Visual Language Of The Transcendent, Selma Fejzullaj

Theses and Dissertations

Adolf Loos’s declaration that “ornament is a crime” defined modernist design, establishing a legacy that dismisses ornamentation as wasteful and regressive. This research questions that legacy by repositioning aesthetics as a divinely grounded value, inspired by the Qur’anic vision of Paradise. In this celestial realm, beauty is not wasteful but a manifestation of divine perfection. Conceptually, the project reclaims ornament as a vital tool for contemplating metaphysical themes. Materially, it reimagines glass, shifting it from modernist "radical honesty" to a medium of layered depth. Recombining traditional Islamic ornamentation practices such as Girih and Chaharbagh, the project evokes the Qur’anic vision …