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2026

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Effect Of Hydrogen Peroxide Concentration On Plasma Arc-Activated Tooth Bleaching: An In Vitro Study, Pei-Ling Lai, Ping-Hui Liao, Po-Sung Fu, Chih-Te Liu, Wen-Cheng Chen, Chun-Cheng Hung Jan 2026

Effect Of Hydrogen Peroxide Concentration On Plasma Arc-Activated Tooth Bleaching: An In Vitro Study, Pei-Ling Lai, Ping-Hui Liao, Po-Sung Fu, Chih-Te Liu, Wen-Cheng Chen, Chun-Cheng Hung

Journal of Dental Sciences

Background/purpose Tooth bleaching was a conservative treatment compared with veneer and crown restorations that causes damage of teeth structure. This study evaluated the effectiveness of different concentrations of hydrogen peroxide combined with plasma arc activation for tooth whitening, focusing on tooth shade, microhardness, and surface roughness. Materials and methods The extracted teeth were standardized to ensure consistent surface conditions. They were bleached using various concentrations of 20 %–35 % hydrogen peroxide, with or without plasma arc activation. After the bleaching process, the shade, microhardness, and surface roughness of the teeth were measured before, during, and after the first and fourth …

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Bacterial–Host Interactions In Periodontal Prognosis: Role Of P. Gingivalis And Il-8, Ying-Chu Lin, Ting-Yi Renn, Chang-Yu Lee, Nai-Chia Teng, Yung-Kai Huang Jan 2026

Bacterial–Host Interactions In Periodontal Prognosis: Role Of P. Gingivalis And Il-8, Ying-Chu Lin, Ting-Yi Renn, Chang-Yu Lee, Nai-Chia Teng, Yung-Kai Huang

Journal of Dental Sciences

Background/purpose The combined effects of Porphromonas gingivalis with other pathogens and host inflammatory on treatment prognosis remain underexplored. This study investigated associations between P. gingivalis bacterial co-infection, salivary IL-8 levels, and prognosis following non-surgical periodontal therapy (NSPT). Materials and methods Seventy-four participants underwent NSPT were recruited. Subgingival specimens were collected before treatment and analyzed by 16S rRNA sequencing. Salivary IL-8 levels and periodontal clinical parameters were recorded at baseline and one month after scaling and root-planing (SRP). Saliva samples were analyzed for IL-8 levels using a commercial kit. Multivariate regression analyses were conducted to assess associations between pathogens, IL-8, and …

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Improvement In Oral Hygiene Among Bedridden Patients Following Domiciliary Dental Care: A Retrospective Study, Min Yee Ng, Chuan-Hang Yu Jan 2026

Improvement In Oral Hygiene Among Bedridden Patients Following Domiciliary Dental Care: A Retrospective Study, Min Yee Ng, Chuan-Hang Yu

Journal of Dental Sciences

Background/purpose Domiciliary dental care (DDC) offers dental services in the comfort of a patient's home, typically for bed-bound patients. Poor oral hygiene in this group has been associated with pneumonia. Although DDC reduces the risk of pneumonia, its impact on oral hygiene has not been explored yet. Therefore, this retrospective study aimed to investigate the effectiveness of DDC in improving oral health in bedridden patients. Materials and methods We retrospectively reviewed individuals who received dental services and evaluated their oral hygiene status using the plaque index (PI). Demographic data (age, sex, cause of bedridden state) and oral findings (DMFT, number …

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Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Activation By Nattokinase Reduces Pro-Inflammatory And Matrix-Degrading Mediators In Human Gingival Fibroblasts, Ya-Lun Li, Yang-Che Wu, Chien-Fu Tseng, Yung-Li Wang, Sin-Yu Li, Thi Vo, Yuh-Lien Chen, Yin-Tzer Shih, I-Ta Lee Jan 2026

Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Activation By Nattokinase Reduces Pro-Inflammatory And Matrix-Degrading Mediators In Human Gingival Fibroblasts, Ya-Lun Li, Yang-Che Wu, Chien-Fu Tseng, Yung-Li Wang, Sin-Yu Li, Thi Vo, Yuh-Lien Chen, Yin-Tzer Shih, I-Ta Lee

Journal of Dental Sciences

Background/purpose Particulate matter (PM) exposure is associated with inflammation and extracellular matrix degradation in periodontal tissues. Cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE2), and matrix metalloproteinase-1 (MMP-1) are key mediators in these processes. Nattokinase, a fibrinolytic enzyme derived from Bacillus subtilis fermentation, has recently gained attention for its potent anti-inflammatory and antioxidant effects. Materials and methods Human gingival fibroblasts (HGF-1 cells) were exposed to PM, and the protective effects of nattokinase pretreatment were systematically evaluated. COX-2, PGE2, and MMP-1 expression and release were analyzed using immunoblotting and enzyme-linked immunosorbent assay. The roles of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-derived reactive oxygen species …

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Laser-Modified Titanium Surfaces Induce Sex-Dimorphic Secretion Of Angiogenic Factors By Gingiva-Derived Mesenchymal Stromal Cells, Ting-Han Chang, Hsin-Han Hou, Yi-Shing Shieh, Her-Hsiung Huang, Da-Yo Yuh Jan 2026

Laser-Modified Titanium Surfaces Induce Sex-Dimorphic Secretion Of Angiogenic Factors By Gingiva-Derived Mesenchymal Stromal Cells, Ting-Han Chang, Hsin-Han Hou, Yi-Shing Shieh, Her-Hsiung Huang, Da-Yo Yuh

Journal of Dental Sciences

Background/purpose Dental implants have been applied to restore missing dentition for more than fifty years. However, whether different surface modification on implant provide topographical cues that alter sex-specific effect on peri-implant angiogenesis remains unclear. This study aimed to investigate whether titanium surface modifications influence sex-specific chromatin accessibility, gene expression, and angiogenesis-related functions in human gingiva-derived mesenchymal stromal cells (GMSCs). Materials and methods We collected health gingival tissues from sixteen subjects (eight females and eight males) and isolated primary GMSCs. The primary GMSCs were cultured on three types of titanium surfaces: machined, lasered, and SLA (sand-blasted, large-grit, acid-etched). Chromatin accessibility and …

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Successful Prevention Of Medication-Related Osteonecrosis Of The Jaw After Dental Extractions By Socket Preservation With Alloplast Plus Tetracycline In Patients Taking Antiresorptive Drugs, Liang-Ho Lin, Chun-Hsiang Wang, Shin-Yu Lu Jan 2026

Successful Prevention Of Medication-Related Osteonecrosis Of The Jaw After Dental Extractions By Socket Preservation With Alloplast Plus Tetracycline In Patients Taking Antiresorptive Drugs, Liang-Ho Lin, Chun-Hsiang Wang, Shin-Yu Lu

Journal of Dental Sciences

Background/purpose Medication-related osteonecrosis of the jaw (MRONJ) is a serious side effect of antiresorptive, antiangiogenic or targeted agents, and usually occurs after dental extraction. The etiopathogenesis of MRONJ is multifactorial and not fully understood. MRONJ remains difficult to treat. Precluding MRONJ occurrence is therefore essential. We offer our experiences and treatment strategies regarding the successful prevention of MRONJ after tooth extractions in patients taking antiresorptive drugs (ARDs). Materials and methods Under ARDs cessation of at least 3 months before and after oral surgery, 106 consecutive patients who underwent 249 dental extractions on 137 occasions were examined according to complete follow-up …

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Tumor Microenvironment-Derived Il-32 Promotes Aggressive Phenotypes And Stem Cell Traits In Head And Neck Squamous Cell Carcinoma, Nien-Tzu Liu, Shin-Hsien Yang, Yi-Ming Chang, Jian-Hong Yu, Su-Feng Chen, Yaoh-Shiang Lin, Yu-Chun Lin Jan 2026

Tumor Microenvironment-Derived Il-32 Promotes Aggressive Phenotypes And Stem Cell Traits In Head And Neck Squamous Cell Carcinoma, Nien-Tzu Liu, Shin-Hsien Yang, Yi-Ming Chang, Jian-Hong Yu, Su-Feng Chen, Yaoh-Shiang Lin, Yu-Chun Lin

Journal of Dental Sciences

Background/purpose Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy distinguished by marked invasiveness, a high metastatic propensity, and poor prognosis. Cancer-associated fibroblasts (CAFs) within the tumour microenvironment secrete numerous mediators that accelerate tumour progression; however, the precise contribution of CAF-derived interleukin-32 (IL-32) remains unclear. This study examined the influence of CAF-derived IL-32 on invasion, epithelial–mesenchymal transition (EMT), and cancer-stem-cell (CSC) traits in HNSCC. Materials and methods Primary CAFs and normal fibroblasts (NFs) were isolated from HNSCC specimens. IL-32 expression was quantified by microarray analysis, quantitative PCR, Western blotting, and enzyme-linked immunosorbent assay. Migration and invasion of FaDu …

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Biofunctionalized 3d-Printed Gelatin-Alginate Scaffolds With Arginine-Glycine-Aspartic Acid (Rgd) Peptides For Enhanced In Vitro Osteogenesis, Ting-Yi Renn, You-Ru Ma, Chia-Chen Hsu, Eisner Salamanca, Hiroshi Egusa, Ying-Sui Sun, Chun-Pin Lin, Wei-Jen Chang Jan 2026

Biofunctionalized 3d-Printed Gelatin-Alginate Scaffolds With Arginine-Glycine-Aspartic Acid (Rgd) Peptides For Enhanced In Vitro Osteogenesis, Ting-Yi Renn, You-Ru Ma, Chia-Chen Hsu, Eisner Salamanca, Hiroshi Egusa, Ying-Sui Sun, Chun-Pin Lin, Wei-Jen Chang

Journal of Dental Sciences

Background/purpose Alveolar bone defects are difficult to treat due to ongoing resorption and limitations of conventional grafts. Tissue engineering strategies, particularly 3D hydrogel-based scaffolds, offer promising alternatives by mimicking the extracellular matrix and supporting cell-driven regeneration. This study aimed to incorporating arginine-glycine-aspartic acid (RGD) peptides into 3D-printed gelatin-alginate hydrogels to enhances their bioactivity and osteogenic potential for effective alveolar bone repair. Materials and methods The physical characterization of RGD peptides-grafted 3D-printed gelatin-alginate scaffolds was conducted using morphological observation, elemental composition analysis, Fourier-transform infrared spectroscopy (FTIR), and assessments of swelling and degradation behavior. Biological performance was examined in vitro through cell …

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Evaluation Of The Performance Of An Artificial Intelligence Model In Recognizing The Habitual Mixed Language In Taiwan For Generating Periodontal Charting Text Reports, Yi-June Lo, Yung-Chun Chang, Chien-Hung Chen, Hsuan-Po Wang, Hao-Chen Wang, Yoichi Ohiro, Chih-Yuan Fang Jan 2026

Evaluation Of The Performance Of An Artificial Intelligence Model In Recognizing The Habitual Mixed Language In Taiwan For Generating Periodontal Charting Text Reports, Yi-June Lo, Yung-Chun Chang, Chien-Hung Chen, Hsuan-Po Wang, Hao-Chen Wang, Yoichi Ohiro, Chih-Yuan Fang

Journal of Dental Sciences

Background/purpose “Periodontal charting” in Taiwan typically involves a two-person collaboration. However, while advances in voice technology has made it feasible to use voice recognition to reduce these manpower demands in English-speaking countries, these artificial intelligent (AI) voice recognition tools have lacked localized features to make them feasible in our context of Taiwan. Materials and methods To fill this research gap, we integrated GPT-4o-transcribe and GPT-4.1-mini into a two-stage system for this study, where stage 1 worked on speech-to-text and stage 2 focused on text-to-report. To evaluate this AI model's performance, five representative periodontal charting scenarios were constructed, and 15 voice …

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Development And Validation Of A Checklist For Evaluating Root Canal Treatment Performance In Taiwan, Tien-Hao Chang, Yong-Chen Huang, Shu-Hui Chang, Stanley Shih-Li Tsai, Yi-Ling Tsai Jan 2026

Development And Validation Of A Checklist For Evaluating Root Canal Treatment Performance In Taiwan, Tien-Hao Chang, Yong-Chen Huang, Shu-Hui Chang, Stanley Shih-Li Tsai, Yi-Ling Tsai

Journal of Dental Sciences

Background/purpose Over the past decade, numerous efforts have been made to develop guidelines for endodontic education; however, there has been no corresponding reform of the assessment scale. This study aimed to adopt an integrative approach to develop a checklist that summarizes the guidelines into key points for evaluating root canal treatment performance. Materials and methods We followed the modified Delphi method and employed a five-step process to develop the checklist. Eight experts were recruited to develop the checklist, each with at least 7 years of clinical dentistry experiences, including a minimum 5 years in endodontics, as well as at least …

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Schneiderian Membrane Perforation Upon The Advancement Of Mechanical Drills Passing Through Sinus Walls: An Ex Vivo Animal Study, Jerry Ching-Yi Lin, Ting-Yi Renn, Chia-Chen Hsu, Wei Jen Chang Jan 2026

Schneiderian Membrane Perforation Upon The Advancement Of Mechanical Drills Passing Through Sinus Walls: An Ex Vivo Animal Study, Jerry Ching-Yi Lin, Ting-Yi Renn, Chia-Chen Hsu, Wei Jen Chang

Journal of Dental Sciences

Background/purpose This ex vivo study aimed to evaluate the perforation of Schneiderian membrane upon the advancement of drills incrementally in 1 mm passing through the sinus during the implant site osteotomy with two different drill types and techniques. Materials and methods Fifty goat heads with 50 pairs of sinuses were assigned to two groups: osseodensification drill (OD) and inverse conical shape drill (ICSD) to simulate transcrestal sinus elevation. Osteotomy was performed to pass through the lateral sinus wall, advancing the drills incrementally in 1 mm until perforation occurred. The integrity of the Schneiderian membranes was confirmed under a microscope. Results …

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Adjuvant Metronomic Tegafur-Uracil Is Associated With Poorer Outcomes And Unfavorable Histopathologic Progression In Oral Squamous Cell Carcinomas, Kai-Feng Hung, Yi-Ping Wang, Yi-Chen Sun, Zhi-Qian Lin, Cheng-Hsien Wu, Peter Chang, Julia Chang Jan 2026

Adjuvant Metronomic Tegafur-Uracil Is Associated With Poorer Outcomes And Unfavorable Histopathologic Progression In Oral Squamous Cell Carcinomas, Kai-Feng Hung, Yi-Ping Wang, Yi-Chen Sun, Zhi-Qian Lin, Cheng-Hsien Wu, Peter Chang, Julia Chang

Journal of Dental Sciences

Background/purpose Tegafur-uracil (UFUR) is widely prescribed as metronomic adjuvant chemotherapy for oral squamous cell carcinoma (OSCC) in East Asia, though its long-term benefit remains unclear. This study aimed to evaluate the oncologic and pathological impact of adjuvant UFUR in a large real-world OSCC cohort spanning three decades. Materials and methods This retrospective, single-institution cohort included 2048 patients with histopathologically confirmed OSCC treated at a tertiary medical center in Taiwan (1990–2020). All underwent curative-intent surgery with or without postoperative radiotherapy or concurrent chemoradiotherapy (CCRT). Among them, 878 patients received adjuvant metronomic UFUR for ≥12 months. Survival outcomes were analyzed using Kaplan–Meier …

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Impact Of Bone Surface Inclination On The Precision Of Static Fully Guided Implant Surgery: A Quantitative Analysis, Shiu-Fong Ou, Szu-Yu Huang, Chia-Yuan Hu, Tsung-Chieh Yang, Tong-Mei Wang Jan 2026

Impact Of Bone Surface Inclination On The Precision Of Static Fully Guided Implant Surgery: A Quantitative Analysis, Shiu-Fong Ou, Szu-Yu Huang, Chia-Yuan Hu, Tsung-Chieh Yang, Tong-Mei Wang

Journal of Dental Sciences

Background/purpose Although static fully guided systems improve the accuracy of implant placement, most studies have focused on flat bone surfaces, with limited exploration of the effects of sloped bone surface. In this study, we aimed to evaluate the effects of bone surface inclination on the accuracy of static fully guided implant surgery. Materials and methods Three 3D-printed maxillary models with a missing upper right lateral incisor were fabricated and each accommodated artificial bone blocks (Sawbones®). Bone blocks were grouped according to the buccal surface inclination (0°, 30°, and 60°; n = 10 per group). A static fully guided surgical system …

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Effects Of Restorative Materials, Colors, And Surface Finishing On The Scanning Accuracy Of An Intraoral Scanner, Sophia Lin, Wei-Chun Lin, Amal Alfaraj Jan 2026

Effects Of Restorative Materials, Colors, And Surface Finishing On The Scanning Accuracy Of An Intraoral Scanner, Sophia Lin, Wei-Chun Lin, Amal Alfaraj

Journal of Dental Sciences

Background/purpose When teeth are restored using dental materials, there is potential for these restorations to influence the accuracy of intraoral scans. Such variations in accuracy could subsequently affect the precision of the derived virtual cast, the registration of the maxillo-mandibular relationship, and the fabrication of prostheses. This study aimed to assess the effect of various restorative materials, prosthesis colors, and their surface finishes on the accuracy of intraoral scans performed with a TRIOS 4 scanner. Materials and methods Using a 4 × 2 × 2 factorial experimental design, the research analyzed how metal-ceramic, zirconia, lithium disilicate, and milled PMMA; shades …

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Apoptosis-Inducing Factor Mitochondria-Associated 2 (Aifm2) Promotes Tumor Progression And Predicts Poor Prognosis In Oral Squamous Cell Carcinoma, Chung-Hsien Chou, Kuo-Wei Chang, Wan-Wen Hung, Miao-An Wei, Chung-Ji Liu, Shu-Chun Lin Jan 2026

Apoptosis-Inducing Factor Mitochondria-Associated 2 (Aifm2) Promotes Tumor Progression And Predicts Poor Prognosis In Oral Squamous Cell Carcinoma, Chung-Hsien Chou, Kuo-Wei Chang, Wan-Wen Hung, Miao-An Wei, Chung-Ji Liu, Shu-Chun Lin

Journal of Dental Sciences

Background/purpose Head and neck squamous cell carcinoma (HNSCC), including oral squamous cell carcinoma (OSCC), remains a major malignancy with limited therapeutic efficacy. Apoptosis-inducing factor mitochondria-associated 2 (AIFM2), also known as ferroptosis suppressor protein 1, regulates ferroptosis and tumor progression. This study investigated the oncogenic function, clinical relevance, and regulation of AIFM2 in OSCC. Materials and methods Transcriptomic data from TCGA HNSCC and in-house OSCC RNA-Seq datasets were analyzed to assess AIFM2 expression and its association with clinicopathological features and outcomes. Functional assays evaluated the effects of AIFM2 knockdown or overexpression on OSCC cell proliferation, migration, invasion, and therapeutic response. MicroRNAs …

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Domiciliary Dental Care Coverage In Taiwan: An Assessment Of Provider Participation And Geographic Distribution Using The Universal Health Coverage Framework, Chuan-Hang Yu Jan 2026

Domiciliary Dental Care Coverage In Taiwan: An Assessment Of Provider Participation And Geographic Distribution Using The Universal Health Coverage Framework, Chuan-Hang Yu

Journal of Dental Sciences

Background/purpose Universal health coverage (UHC) ensures access to needed health services without financial hardship. While Taiwan has achieved near-universal coverage for most medical services, domiciliary dental care (DDC) for people with mobility limitations remains poorly integrated into the UHC framework. This study assessed DDC coverage in Taiwan using the World Health Organization UHC framework. Materials and methods Publicly available 2024 data were analyzed for dental institutions, practicing dentists, DDC providers, and long-term care populations across Taiwan's six National Health Insurance (NHI) regions and 22 administrative districts. Geographic distribution was examined using provider density metrics, Lorenz curves, and Gini coefficients. Results …

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Apobec3b/Asf1b–Tgf-Β Signaling Axis Promotes Epithelial–Mesenchymal Transition In Hpv-Positive Oropharyngeal Cancer, Ming-Shou Hsieh, Chih-Chi Sheen, Tung-Nien Hsu, Chi-Tai Yeh, Wei Jen Chang, Yang-Che Wu Jan 2026

Apobec3b/Asf1b–Tgf-Β Signaling Axis Promotes Epithelial–Mesenchymal Transition In Hpv-Positive Oropharyngeal Cancer, Ming-Shou Hsieh, Chih-Chi Sheen, Tung-Nien Hsu, Chi-Tai Yeh, Wei Jen Chang, Yang-Che Wu

Journal of Dental Sciences

Background/purpose Human papillomavirus (HPV)-positive oropharyngeal cancer (OPC) generally shows better outcomes, yet a subset of patients develops aggressive lymphatic metastasis. The molecular determinants of this divergence remain unclear. This study explored the apolipoprotein B mRNA editing enzyme catalytic subunit 3B (APOBEC3B)/anti-silencing function 1B histone chaperone (ASF1B) axis as a potential mediator linking human papillomavirus (HPV) infection, DNA damage, and transforming growth factor beta (TGF-β) signaling in OPC. Materials and methods Transcriptomic and clinical datasets from The Cancer Genome Atlas (TCGA) were analyzed to examine correlations among APOBEC3B/ASF1B expression, HPV status, and TGF-β signaling activity. Functional assays using HPV-positive and HPV-negative …

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Characterization Of The Oral Microbiota In Zygomatic Versus Dental Implants: Implications For Full-Mouth Rehabilitation, Min-Yi Sung, Po-Chih Hsu, Chan-Yen Kuo, Liang-Kun Chen, Chung-Che Tsai, Yi-Chiung Hsu Jan 2026

Characterization Of The Oral Microbiota In Zygomatic Versus Dental Implants: Implications For Full-Mouth Rehabilitation, Min-Yi Sung, Po-Chih Hsu, Chan-Yen Kuo, Liang-Kun Chen, Chung-Che Tsai, Yi-Chiung Hsu

Journal of Dental Sciences

Background/purpose Dental implants are widely used to restore oral function and esthetics in patients with tooth loss. General zygomatic implants (GZIs) are a valuable alternative for patients with severely atrophic maxillae or post-oncologic defects. However, implant placement can alter the ecological balance of the oral microbiota, potentially influencing peri-implant and sinus-related diseases. Because GZIs often traverse or adjoin the maxillary sinus, their microbial environment may differ from that of general dental implants (GDIs). This study aimed to compare microbiota taxonomy between GZI and GDI sites. Materials and methods Generally healthy adults treated with either general zygomatic implants (GZI group) or …

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Prevention Of Medication-Related Osteonecrosis Of The Jaw After Tooth Extraction By Local Administration Of Antibiotics And Atelocollagen Sponge: A Preliminary Study, Natsumi Nakamura, Sakiko Soutome, Akira Imakiire, Satoshi Rokutanda, Seigo Ohba, Shunsuke Sawada, Yuka Kojima, Yuki Sakamoto, Yoshiko Yamamura, Madoka Funahara, Mitsunobu Otsuru, Masahiro Umeda Jan 2026

Prevention Of Medication-Related Osteonecrosis Of The Jaw After Tooth Extraction By Local Administration Of Antibiotics And Atelocollagen Sponge: A Preliminary Study, Natsumi Nakamura, Sakiko Soutome, Akira Imakiire, Satoshi Rokutanda, Seigo Ohba, Shunsuke Sawada, Yuka Kojima, Yuki Sakamoto, Yoshiko Yamamura, Madoka Funahara, Mitsunobu Otsuru, Masahiro Umeda

Journal of Dental Sciences

Background/purpose Medication-related osteonecrosis of the jaw (MRONJ) often develops after extraction of a tooth with a local infection. Therefore, it is necessary to develop extraction methods that can prevent MRONJ. Before examining whether antibiotics and atelocollagen administered in the extraction socket can prevent the development of MRONJ after tooth extraction, this study was conducted to determine the appropriate antibiotics concentration and to conduct a clinical study with a small number of cases as a preliminary study. Materials and methods First, a mixture of minocycline and atelocollagen at different concentrations was implanted into the bone cavity formed in the rabbit head, …

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A Scientometric Study On Methylation Modification And Identification Of Related Genes In Oral Potentially Malignant Disorders And Oral Cancer, Lifen Yin, Xiaoliang Luo, Jian Liu, Wei Liu, Liying Gu Jan 2026

A Scientometric Study On Methylation Modification And Identification Of Related Genes In Oral Potentially Malignant Disorders And Oral Cancer, Lifen Yin, Xiaoliang Luo, Jian Liu, Wei Liu, Liying Gu

Journal of Dental Sciences

Background/purpose Accumulating evidence indicates that methylation modification alterations involve in the development and progression of oral cancer. The purpose of this study was to analyze the scientometric characteristics of methylation modification in oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC). Materials and methods All the papers on methylation research in OPMD/OSCC were comprehensively retrieved from the Scopus database with emphasis on the identification of methylation related genes. Results A total of 365 papers on methylation research in OPMD/OSCC were retrieved. The total citation count was 9998 and the h index was 53 for all the papers. The …

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A Scientometric Study On Research Trends And Characteristics Of Randomized Controlled Trials In Orthodontics, Ning Wang, Yang Yu, Linjun Shi, Zhechen Zhang, Jianwei Song Jan 2026

A Scientometric Study On Research Trends And Characteristics Of Randomized Controlled Trials In Orthodontics, Ning Wang, Yang Yu, Linjun Shi, Zhechen Zhang, Jianwei Song

Journal of Dental Sciences

Background/purpose In evidence-based approaches to orthodontic research, randomized controlled trials (RCTs) are recognized as the highest level of original evidence. The purpose of this study was to analyze the scientometric characteristics and research trends of RCTs in orthodontics, with emphasis on chronological comparison and regional characteristic of the keywords. Materials and methods All the reports on RCTs in orthodontics were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2020 and Jan 2020–Jul 2025 in the analysis of research trends. Results There were 1343 reports on RCTs in orthodontics, with total citations of 27,314 and …

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Navigation-Guided Autotransplantation: A Novel Technique For Precise And Predictable Tooth Placement, Yang-Chih Chou, Wen-Hui Chen, Hui-Na Lee, Yu-Feng Chen Jan 2026

Navigation-Guided Autotransplantation: A Novel Technique For Precise And Predictable Tooth Placement, Yang-Chih Chou, Wen-Hui Chen, Hui-Na Lee, Yu-Feng Chen

Journal of Dental Sciences

Autotransplantation (AT) is a promising alternative for restoring failed teeth. However, the success rate varies due to technique sensitivity and absence of standardized protocol. We present the first documented AT protocol utilizing a dynamic navigation system, including three core innovations: (1) navigation-guided socket preparation, (2) extra-alveolar retrograde filling, and (3) digital lingual stent fixation with flowable resin. A 55-year-old Taiwanese female with a vertical root fracture in tooth 36 underwent dynamic navigation-guided AT of tooth 38. The recipient area was prepared using a 2.5 mm wide round bur under the X-Guide® navigation. The X-Mark® probe was used to detect underprepared …

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A Scientometric And Comparative Study Of Rhabdomyosarcoma Research By Pediatricians And Stomatologists, Wenke Chen, Hui Li, Zhenhu Ren, Chongfang Zhang Jan 2026

A Scientometric And Comparative Study Of Rhabdomyosarcoma Research By Pediatricians And Stomatologists, Wenke Chen, Hui Li, Zhenhu Ren, Chongfang Zhang

Journal of Dental Sciences

Background/purpose Rhabdomyosarcoma (RMS) frequently affects pediatric patients and common occurs in the head and neck region. The purpose of this study was to compare the scientometric characteristics of RMS publications by pediatricians and stomatologists. Materials and methods All the papers on RMS were comprehensively retrieved from the Scopus database, and divided into pediatricians and stomatologists groups. Results There were 2211 and 234 papers on RMS were published by rheumatologists and stomatologists, respectively. The total citation count was 63,868 and the h index was 111 for RMS publications by pediatricians, while the respective values for stomatologists were 2952 and 29. The …

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A Scientometric Study On Research Trends And Characteristics Of Mucoepidermoid Carcinoma Of Salivary Glands, Xiuyin Wu, Yawen Ji, Ke Bi, Zhen Wang, Meili Sun Jan 2026

A Scientometric Study On Research Trends And Characteristics Of Mucoepidermoid Carcinoma Of Salivary Glands, Xiuyin Wu, Yawen Ji, Ke Bi, Zhen Wang, Meili Sun

Journal of Dental Sciences

Background/purpose Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of the salivary glands. The purpose of this study was to analyze the scientometric characteristics and research trends of salivary MEC. Materials and methods All the papers on salivary MEC were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2014 and Jan 2014–Jun 2025 in the analysis of research trends. Results There were 1308 papers on salivary MEC, with total citations of 24,598 and the h index of 70. The most frequent location of MEC involved was parotid gland, followed by minor saliva gland …

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Dental Caries Prevalence And Age-Related Patterns Among Populations Remaining In War-Affected Regions Of Ukraine, En-Tse Yen, Sung-Hsien Chiu, Wei-De Tsai, Gen-Min Lin, Kun-Zhe Tsai Jan 2026

Dental Caries Prevalence And Age-Related Patterns Among Populations Remaining In War-Affected Regions Of Ukraine, En-Tse Yen, Sung-Hsien Chiu, Wei-De Tsai, Gen-Min Lin, Kun-Zhe Tsai

Journal of Dental Sciences

Background/purpose The ongoing war in Ukraine has severely disrupted healthcare infrastructure, limiting access to preventive and restorative dental services. Most existing studies have focused on refugees abroad, while data from civilians who remained in conflict-affected regions are scarce. This study aimed to assess dental caries experience and age-related patterns among war-affected regions of Ukraine. Materials and methods A multinational medical team, in collaboration with local health institutions, delivered humanitarian medical and dental services in conflict-affected regions of Ukraine between September 17 and September 30, 2025. We retrospectively analyzed medical records from 230 civilians aged 12–85 years, assessing substance use, oral …

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Long-Term Stability Of Implant Site-Switching Technique And Early Orthodontic Loading: A 16-Year Case Report, Tony Shing-Zeng Dung, Yuan-Yang Hsu, Cheng-Shan Li Jan 2026

Long-Term Stability Of Implant Site-Switching Technique And Early Orthodontic Loading: A 16-Year Case Report, Tony Shing-Zeng Dung, Yuan-Yang Hsu, Cheng-Shan Li

Journal of Dental Sciences

No abstract provided.

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Plunging Ranula With Extension To The Tongue Base, Satomi Sugiyama, Toshinori Iwai, Masaki Yoda, Kenji Mitsudo Jan 2026

Plunging Ranula With Extension To The Tongue Base, Satomi Sugiyama, Toshinori Iwai, Masaki Yoda, Kenji Mitsudo

Journal of Dental Sciences

No abstract provided.

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Furcation-Involved Class Ii Subclass B Molar Treated By Er:Yag Laser-Assisted Comprehensive Periodontal Pocket Therapy (Er-Lcpt) Under A Microscope: A Case Report, Taichen Lin, Min Yee Ng, Yoichi Taniguchi, Akira Aoki Jan 2026

Furcation-Involved Class Ii Subclass B Molar Treated By Er:Yag Laser-Assisted Comprehensive Periodontal Pocket Therapy (Er-Lcpt) Under A Microscope: A Case Report, Taichen Lin, Min Yee Ng, Yoichi Taniguchi, Akira Aoki

Journal of Dental Sciences

No abstract provided.

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No Evidence Supporting A Causal Link Between Orthodontic Premolar Extraction And Obstructive Sleep Apnea Despite Radiographic Airway Changes, Nia Ayu Ismaniati Noerhadi, Tsui-Hsein Huang, Chun-Te Ho, Chia-Tze Kao Jan 2026

No Evidence Supporting A Causal Link Between Orthodontic Premolar Extraction And Obstructive Sleep Apnea Despite Radiographic Airway Changes, Nia Ayu Ismaniati Noerhadi, Tsui-Hsein Huang, Chun-Te Ho, Chia-Tze Kao

Journal of Dental Sciences

No abstract provided.

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The Health Screening Measure For Ionizing Radiation Workers Under The Labor Insurance In Taiwan: A Case Study Of Dental Assistant Health Management In A Dental Clinic, Feng-Chou Cheng, Ling-Hsia Wang, Yu-Ling Wu, Chun-Pin Chiang Jan 2026

The Health Screening Measure For Ionizing Radiation Workers Under The Labor Insurance In Taiwan: A Case Study Of Dental Assistant Health Management In A Dental Clinic, Feng-Chou Cheng, Ling-Hsia Wang, Yu-Ling Wu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

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