Digital Commons Network^™

Efficacy And Safety Of Pyrimidine Nucleos(T)Ide Therapy In Thymidine Kinase 2 Deficiency, Michio Hirano, Caterina Garone, Richard Haas, Carmen Paradas, Fernando Scaglia, Irene Rebollo Mesa, Carl Chiang, Anny-Odile Colson, Susan Vanmeter, Cristina Domínguez-González

Faculty, Staff and Students Publications

Thymidine kinase 2 deficiency (TK2d) (MIM 609560) is an ultra-rare, autosomal recessive mitochondrial myopathy caused by TK2 variants, leading to mitochondrial DNA depletion and/or multiple deletions. People with thymidine kinase 2 deficiency experience progressive myopathy, bulbar weakness and respiratory insufficiency, often losing the ability to walk, eat and breathe independently. Doxecitine and doxribtimine represents the first approved treatment for patients with thymidine kinase 2 deficiency with age of symptom onset ≤12 years by the US Food and Drug Administration and the European Medicines Agency; previously, disease management was limited to supportive care. We investigated the efficacy and safety of pyrimidine …

Reframing Trauma-Informed Care For Refugee And (Im)Migrant Health Systems: From Interpersonal Practice To Structurally Embedded Care, Hyojin Im, Sophia Banu, Aisha Koroma, Sarmaya Mustafayeva

Faculty, Staff and Students Publications

No abstract provided.

Transition To Tenecteplase Is Associated With Shorter Door-To-Puncture Times: A Retrospective Study From The Lone Star Stroke Consortium Tnk Registry, Anqi Luo, Sujani Bandela, Gretchel Gealogo-Brown, Mark P Goldberg, Andrew Slusher, Reza Behrouz, Alibay Jafarli, Siddarth Prasad, Daiwai Olson, Maria Denbow, Mehari Gebreyohanns, Asmiet Techan, Chethan P Venkatasubba Rao, Jane A Anderson, Barbara Kimmel, Anette Ovalle, Michele Patterson, Sean I Savitz, Salvador Cruz-Flores, Steven Warach, Lee Birnbaum

Faculty, Staff and Students Publications

Background: Intravenous thrombolytic (IVT) and mechanical thrombectomy (MT) therapies are the current standard of care for large vessel occlusion (LVO) stroke. Multiple studies emphasized the impact of time metrics on patient outcomes, particularly door-to-needle (DTN) and door-to-puncture (DTP) times. Tenecteplase (TNK) offers potential advantages over alteplase (ALT), including a simplified one-time bolus administration, which may reduce DTP time. Results suggest TNK is non-inferior to ALT in terms of clinical outcomes, but few large cohort studies have compared DTP time for patients receiving TNK vs. ALT prior to thrombectomy. This real-world study aimed to compare DTP times and discharge outcomes in …

Suicidal Ideation In Spinocerebellar Ataxia, Levi Peppel, Ruo-Yah Lai, Christian Rummey, Puneet Opal, Jeremy D Schmahmann, Christopher M Gomez, Henry Paulson, Theresa A Zesiewicz, Susan Perlman, George Wilmot, Sarah H Ying, Chiadi U Onyike, Khalaf O Bushara, Michael D Geschwind, Karla P Figueroa, Stefan M Pulst, Sub H Subramony, Antoine Duquette, Tetsuo Ashizawa, Ali G Hamedani, Marie Y Davis, Sharan R Srinivasan, Matthew R Burns, Nadia Amokrane, Lauren R Moore, Vikram G Shakkottai, Liana S Rosenthal, Sheng-Han Kuo, Chi-Ying R Lin

Faculty, Staff and Students Publications

Objective: Suicidal ideation has not been extensively studied in spinocerebellar ataxias (SCAs). The authors examined whether individuals with SCAs have increased suicidal ideation and related factors.

Methods: The authors studied patients with genetically confirmed SCAs enrolled in the Clinical Research Consortium for the Study of Cerebellar Ataxia cohort, examining the percentages of patients with SCA subtypes 1, 2, 3, and 6 who reported suicidal ideation and comparing findings with nationally representative data from the National Survey on Drug Use and Health (NSDUH). Clinical characteristics that may contribute to suicidal ideation in SCAs, including age, disease duration, sex, ataxia severity, depression, …

Understanding Wage Theft: Beyond The Numbers Through Community Practice, Lived Experience, And Research, André Simões Da Silva, Lenita Reason, Cristina Araujo Brinkerhoff

Gastón Institute Publications

Wage theft is a widespread form of labor exploitation that disproportionately affects immigrant and other vulnerable workers. This report examines the scope and impact of wage theft in Massachusetts by analyzing case data from the Brazilian Worker Center (BWC) alongside wage and labor enforcement data from the Massachusetts Attorney General’s Office (AGO). The analysis demonstrates how wage theft affects immigrant workers across industries, with particularly high numbers of cases in construction, cleaning, and hospitality. The data also reveal significant gaps in the reporting and enforcement of wage violations, particularly among domestic workers, whose cases are likely substantially underrepresented in available …

Press Release - Carol Anderson, Lewis & Clark Law School

MLK 2026 Event Information

No abstract provided.

This Is A Test, John Smith

Early Childhood and Community Research and Development Initiative (ECRDI)

No abstract provided.

Research News, Grants, 2026, Volume 1, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during January - March 2026

Research News, Grants, 2026, Volume 2, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during April - June 2026

Research News, Grants, 2026, Volume 3, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during July - September 2026

Faculty Fellowships: Knot Theory In The Bay Area, Anthony Bosman

Faculty Publications

No abstract provided.

A New Kind Of Muslim?: Islamic Identity, Digital Media And Youth In Oman, The "Switzerland Of The Middle East.", Paulo C. Oliveira

Faculty Publications

No abstract provided.

Faculty Fellowships: River Dolphins In Bangladesh., Daniel Gonzalez-Socoloske

Faculty Publications

No abstract provided.

Modern Research Tools Supporting Science At Andrews University, Peter Lyons, Henry Navarro

Faculty Publications

No abstract provided.

Going On Vocation, Rodney Palmer

Faculty Publications

No abstract provided.

The Measure Of Librarianship: How Accessibility, Compassionate Service, And Practical Action Reveal The Heart Of Adventist Librarianship, Zorislav Plantak

Faculty Publications

No abstract provided.

Can You Hear Me Now?, Daniel Gonzalez, Amanda Moore

Faculty Publications

No abstract provided.

Scripture Spotlight: What Was The Role Of The Scapegoat?, Roy Gane

Faculty Publications

No abstract provided.

Effect Of Density Irregularities On Radio Frequency Wave Propagation In Ionospheric Plasmas, Eun-Hwa Kim, Jay Johnson, Syun'ichi Shiraiwa, Nicola Bertelli, Masayuki Ono, Simon Wing

Faculty Publications

No abstract provided.

Effects Of Density Turbulence On Helicon Wave Propagation In The Core Plasmas, Eun-Hwa Kim, Syun'ichi Shiraiwa, Seung-Hoe Ku, A. Bortolon, Masayuki Ono, Nicola Bertelli, Robert I. Pinsker

Faculty Publications

No abstract provided.

Full-Wave Modeling Of Rf Waves In Fusion Plasmas With Finite Element Method: Progress In Past Decades And Its Future Role, Syun'ichi Shiraiwa, Nicola Bertelli, Eun-Hwa Kim

Faculty Publications

No abstract provided.

Existence, Nonexistence And Uniqueness Of Positive Solution To A General Elliptic System With Fixed Or Perturbed Growth Rates, Joon Hyuk Kang, Noah Koliadko

Faculty Publications

No abstract provided.

Low Frequency Oscillation Observed In The Ionosphere Around The Substorm Onsets, Simon Wing, Elmer Rivera, A. J. Hull, P. A. Damiano

Faculty Publications

No abstract provided.

Discipling The Youth Through Preaching, Rodney Palmer

Faculty Publications

No abstract provided.

A Different Starting Point: Youth Discipleship For A New Generation, Rogelio Paquini

Faculty Publications

No abstract provided.

Understanding How Emotional Intelligence Training And Awareness Can Enhance The Effectiveness Of Campus Discipleship Activities, Scott R. Ward, Natasha Richards, Sara C. Ward

Faculty Publications

No abstract provided.

Investigation Of Causal Relationships Of The Cross-Scale Wave Coupling Through Information Theoretical Approach, Elmer Rivera, J. Johnson, Simon Wing, Eun-Hwa Kim, Khan-Hyuk Kim, Katariina Nykyri

Faculty Publications

No abstract provided.

The Study Of The Quasi-Periodicity Observed On Plasma Density And Magnetic Field On Saturn's Magnetosphere: An Information Theory Approach, B. R. Neupane, J. R. Johnson, P. A. Delamere, Simon Wing, A. Sciola, K. Sorathia, Joe Caggiano, B. Mino, Colby Maxim

Faculty Publications

No abstract provided.

A Predator-Prey Biological Model Of Multiple Species With Linear Growth Rates, Joon Hyuk Kang

Faculty Publications

No abstract provided.

Between Two Worlds: Parenting Immigrant Children With Wisdom And Resilience, Ainsworth E. Joseph

Faculty Publications

No abstract provided.