Digital Commons Network^™

Importance Of Strength Training To Prevent Secondary Lower Limb Musculoskeletal Injury In Military Personnel, Peter Ladlow, Russell J. Coppack, Robyn P. Cassidy, Rachel Rodgers, Robert Barker-Davies, Paul Comfort, Nicholas J. Ripley, Christopher Bramah, Colin Suffield, Debra Hayhurst, Marina De Vecchis, Samual R. Higgins, Alexander N. Bennett, Oliver O’Sullivan

Research outputs 2022 to 2026

Considerable operational and financial costs are associated with musculoskeletal injury (MSKI) across military organisations. Following an MSKI, reaching ‘medically fully deployable’ status is often contingent on meeting physical employment standards. Strength training has a critical role to play in military physical preparation, injury mitigation and guiding rehabilitation practice. Low levels of muscle strength are associated with increased MSKI risk, and previous MSKI is a leading risk factor for re-injury. When an MSKI does occur, it is essential that all attempts to mitigate the risk of secondary MSKI are met. Maximal force (muscle strength) and rapid force (rate of force development …

Examining Links Between Somatosensation And Cognition In Children With Hemiplegic Cerebral Palsy, Kassandra M. Hewitt, Donna M. Bayliss, Belinda A. Mclean, Ashleigh L. Thornton, Jonson J. Moyle

Research outputs 2022 to 2026

Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While somatosensation may relate to cognitive functioning in CP, this relationship has not previously been investigated. This cross-sectional study examined the relationship between somatosensation and cognition in children with hemiplegic CP, and whether the pattern of brain injury, classified using an established MRI classification system, moderates this relationship. Forty-seven children (26 females) with hemiplegic CP participated (mean age = 11.0 years; SD = 3.6; range: 6–16 years). Parent questionnaires provided demographic, educational, …

Feeling Giggity: Ambiguous Emojis In Teaching And Learning Communications, Mary Kynn, Nicole Reinke, Eva Hatje

Research outputs 2022 to 2026

There is an increase in the number of digital platforms used in higher education classrooms that promote using emojis to capture students’ emotions. However, there is little evidence to suggest that interpretation of emojis is reliable in this context. This pilot project explored if emojis can reliably signify the emotions expressed by first-year university students. Students were asked to record their emotions by selecting a representative emoji and using free text to describe its meaning. A total of 72 responses were recorded in an anonymous online survey. Happy face emojis were used more frequently than emojis representing neutral or unpleasant …

Influence Of Prior Alkalosis Or Acidosis On Physiological Responses During Passive Hyperthermia, Jacky Soo, Shernise Ng, Chris Abbiss, Olivier Girard, Mohammed Ihsan

Research outputs 2022 to 2026

This study manipulated the blood pH of participants to be mildly acidic or basic prior to passive hyperthermia to examine its effects on thermoregulatory and chemo-regulatory responses, including ventilatory parameters, rectal temperature (Tre) and thermal perception. Twelve healthy males attended three experimental sessions in a double-blind, randomised, counterbalanced design. Passive hyperthermia was induced by hot water immersion at 40°C following the consumption of corn starch (placebo; PLA), ammonium chloride (AC) or sodium bicarbonate (SB). Compared with PLA, SB consumption increased blood pH and HCO3⁻, whilst AC decreased both blood pH and HCO3⁻ (all P <  0.001). Specifically, minute ventilation was unchanged following SB (11.0 ± 3.7 L min⁻¹) but …

Intravenous Infusion Of Nicotinamide Adenine Dinucleotide (Nad+) Versus Nicotinamide Riboside (Nr): A Retrospective Tolerability Pilot Study In A Real-World Setting, Kirsten Reyna, Greer Heinzen, Nikita Patel, Marie Ritter, Alexandra Siojo, Henry Legere, Rachele Pojednic

Research outputs 2022 to 2026

Background: Nicotinamide adenine dinucleotide (NAD⁺) is a cofactor for NAD⁺-dependent enzymes that regulate DNA repair, cellular metabolism, and immune function. Supplementation with NAD⁺ and its precursors is commonly used to prevent age-related disease and extend healthspan. Commercial clinical and wellness settings increasingly provide intravenous (IV) NAD⁺ and nicotinamide riboside (NR) despite limited evaluation of safety and effectiveness. These considerations are important, as NAD⁺ and its precursors differ in reported side effects, cellular uptake, and metabolism. This study sought to compare commercially administered NAD⁺ IV and NR IV in humans by evaluating infusion …

Midwifery Students' Definitions Of Normal Labor And Birth: A Study From Five Countries, Jalana Lazar, Juliet Wood, Jane Fry, Barbara Baranowska, Urszula Tataj-Puzyna, Debora Dole, Emma Ritchie, Clare Davison, Cindy L. Farley, Felicity Agwu Kalu, Maria Healy, Maria Węgrzynowska

Research outputs 2022 to 2026

Introduction: Internationally, many women and birthing people are receiving maternity care interventions as a routine with no medical indication for their use. This medicalized environment influences midwives' practice and, by extension, midwifery students' clinical learning experiences, gaining knowledge and confidence in facilitating normal labor and birth. To educate midwifery students in the provision of high-quality maternal and newborn care, it is important to explore their understanding of normal labor and birth, as this underpins their philosophy of care and will inform their future practice. Methods: An online survey was developed from a review of current evidence. Following ethical approval, the …

Obesity Indices As Predictors Of Metabolic Syndrome: 1-Year Findings From A Peruvian Cohort Of Private Educational Institution Workers, Vicente A. Benites-Zapata, Daniel Fernandez-Guzman, Percy Herrera-Añazco, Enrique Moncada-Mapelli, Diego Urrunaga-Pastor, Carlos J. Toro-Huamanchumo

Research outputs 2022 to 2026

Background: Metabolic syndrome (MetS) is a common condition marked by abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. It has significant health and economic impacts, highlighting the need for early predictive markers. Objective: To compare the prognostic performance of various obesity indices in the 1-year incidence of MetS among adult employees of a private educational institution. Design: Cohort study. Methods: A prospective cohort study was conducted using data from adults employed at a private educational institution in Lima, Peru. Participants were enrolled in 2019 and followed for 1 year to monitor anthropometric and biochemical parameters. The outcome was the development of …

Perceived Realism, Place Attachment, And Residents' Support And Involvement: Towards Resident-Centric Film Tourism Development, Deborah Castro, Sangkyun Kim, S. Mostafa Rasoolimanesh, Songshan Huang

Research outputs 2022 to 2026

This study introduces the concept of perceived realism to (film) tourism studies and examines its effect in combination with place attachment on residents' support for and involvement in film tourism development. Partial least squares structural equation modelling (PLS-SEM) and fuzzy-set Qualitative Comparative Analysis (fsQCA) were applied to a sample of 401 Barcelona residents to explore both symmetrical and asymmetrical relationships among the research constructs. The PLS-SEM revealed that events-focused external realism affects residents' support for film tourism development, while narrative realism affects their involvement in film tourism development. In addition, place attachment directly affects residents' support for and involvement in …

Personal Family-Centred Care For Lgbtq+ Individuals In Acute Hospital Settings: A Scoping Review, Gideon U. Johnson, Bianca Ysabelle Esmeralda, Stephen Pearson, Beverley Ewens, Louise Rose

Research outputs 2022 to 2026

Aim: To identify and synthesise existing evidence on family-centred care for Lesbian, Gay, Bisexual, Transgender, Queer and other diverse identities (LGBTQ+) people in acute hospital settings, including hospital-based palliative care, oncology, general in-patient and intensive care. Design: A scoping review guided by the JBI methodology. Methods: Nine databases and grey literature sources were searched. Inclusion criteria focused on LGBTQ+ adults and family-related care experiences in hospital-based acute settings. After screening, qualitative, quantitative, and narrative data were extracted. Thematic analysis synthesised findings, with quantitative data narratively integrated. Data Sources: Searches were conducted across nine databases and grey literature up to April …

Preparation Of Australian Nurses For Contemporary Disability Care: A Desktop Review, Lesley Andrew, Martina Costello

Research outputs 2022 to 2026

Approximately 18% of Australians experience disability, with significant health inequities documented in this population. Despite nursing’s crucial role in addressing these inequities, questions remain about nurses’ preparedness to work effectively with people with disability. The review assessed Australian nursing education’s approach to prepare its graduate nurses for disability care in today’s Australia. Using a rigorous desktop analysis methodology, the review evaluated the publicly available undergraduate nursing degree curricula materials from all 32 Australian public universities that offered a preregistration nursing degree in 2024. The review found 50% of nursing degree curricula course materials omitted to mention disability in their publicly …

Sales Prediction In Omnichannel Distribution Systems Based On Consumer Behavior Using Process Mining And Arimax, Ferra Arik Tridalestari, Mustafid Mustafid, Ferry Jie, Hanung Nindito Prasetyo

Research outputs 2022 to 2026

Omnichannel distribution integrates multiple sales channels into a single management platform to enhance customer experience. However, the complexity of consumer behavior data across channels often prevents business owners from effectively analyzing and predicting sales. This study proposes a sales prediction model in omnichannel distribution systems based on consumer behavior using a collaborative approach that integrates process mining and autoregressive integrated moving average with exogenous variables (ARIMAX). Event log data from an omnichannel service provider were used to extract consumer activity patterns, which were then analyzed through process discovery algorithms to identify dominant behavioral processes. The resulting behavioral indicators served as …

Schools, Space And Atmospheres: The Value Of Student Videos In Negotiating Contested Spaces In New Urban Vertical Schools, Prue Miles, Kylie Boltin, Stuart Poyntz, Jill Willis

Research outputs 2022 to 2026

Voices of young people are essential in civic discourse about thriving futures. Yet dialogue can be complicated when the experiences of adults and young people are vastly different, for example in school spaces designed by adults in cities designed for adults. Vertical, highrise inner city schools represent this intersection. A new genre of school in Australia, vertical schools symbolise aspirations for young people and livable cities as designed by adults. This paper draws from data collected in the Thriving in Vertical Schools project to explore the importance of affective learning atmospheres for students, and the value of digital stories to …

Spatio-Temporal Responses Of A Migratory Shorebird Community Reflect Complex Trade-Offs Among Overabundance Of Predators And Disturbance, K. M. Aarif, Aymen Nefla, Zuzana Musilova, Petr Musil, Sora M. Estrella

Research outputs 2022 to 2026

Animal selection of foraging grounds is a trade-off among available feeding resources, intra and interspecific competition, disturbance and predation risks. The present study was carried out at Kadalundi-Vallikkunnu Community Reserve on the West coast of Kerala (India) in the Central Asian Flyway. The Reserve hosts different coastal habitats, including mudflats, mangroves and sand beaches, and although 31 species of shorebirds are commonly present, it is heavily impacted by human activities. The findings highlight the necessity of robust management of anthropogenic waste and reveal the detrimental impacts of human activities on species communities of conservation concern. We investigated how the densities …

Sugar Consumption In Aboriginal Children Explored From A Social Practice Perspective, Amy Budrikis, Angela Durey, Dan Mcaullay, Paul Ward, Hanny Calache, Thierry Ng, Roma Winmar, Linda Slack-Smith

Research outputs 2022 to 2026

Australian Aboriginal children have higher sugar intake and are disproportionately affected by sugar-related diseases such as obesity, diabetes and dental caries than non-Aboriginal children. The intention of this paper was to highlight the need for approaches that can capture the complexity of health practices without reducing them to either individual choice or structural determination. We explore sugar consumption in Aboriginal children from a social practice perspective. Here, the unit of analysis is the practice, not the individual, where the elements of a social practice (competence, materials and meanings) are integrated into its performance. We conducted qualitative research using elements of …

Sustaining Caring Mobilities In Immobility Regimes: Adaptive Strategies Of Vietnamese Migrant (Grand)Parents In Australia, Hien Thi Nguyen, Catriona Turnbull, Loretta Baldassar

Research outputs 2022 to 2026

(Grand)parents are increasingly traveling internationally to visit and spend time with their transnational families. This mobility is essential to provide informal, unpaid care, driven by globalisation as family members relocate for study and work. However, governments in receiving countries like Australia are implementing restrictive measures, defined in the literature as ‘immobility regimes’, to control the movement of older migrants into their territories, including overseas (grand)parents. Drawing on the lived experiences of 22 Vietnamese migrants (11 (grand)parent visitors and 11 adult migrants who host their (grand)parent visitors), this paper explores the relationship between transnational mobility and institutional migration policies in the …

Systematic Literature Mapping: Integrated System Of Logistic Distribution For Island, Eka Suswaini, Mochammad Agung Wibowo, Ferry Jie

Research outputs 2022 to 2026

Purpose: The study aims to identify and compare various methods used to optimize supply chain distribution, with a focus on uncovering novel approaches. It particularly addresses the gap in logistics distribution models tailored for island environments, proposing the development of an integrated information system using genetic and memetic algorithms to handle uncertainties like weather and vessel availability. Design/methodology/approach: A Systematic Literature Mapping (SLM) approach was adopted. The K-Chart method was applied to categorize conceptual strategies and identify research gaps. A case study was also included to analyze logistical challenges in island settings, incorporating real data variables like transportation schedules and …

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes At Aβ-Pet Centiloid 15, Mean Age Of 66 Years, Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey-Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph Martins, Colin L. Masters, James Doecke

Research outputs 2022 to 2026

Objective: Sporadic late-onset Alzheimer's disease (AD) is characterized by a long pre-clinical phase where amyloid-beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ-PET) and plasma Aβ42/40 become abnormal. Methods: Two high performance immunoprecipitation-mass spectrometry (IP-MS) assays (WashU/C2N and Shimadzu) were tested on samples from 1,450 participants who were diagnosed as cognitively unimpaired (CU), mild cognitive impairment (MCI), or AD-dementia across 4 international cohorts. Natural history modeling and trajectory analyses of the combined Aβ-PET …

ℵ-Ipomdp: Mitigating Deception In A Cognitive Hierarchy With Off-Policy Counterfactual Anomaly Detection, Nitay Alon, Joseph M. Barnby, Stefan Sarkadi, Lion Schulz, Jeffrey S. Rosenschein, Peter Dayan

Research outputs 2022 to 2026

Social agents with finitely nested opponent models are vulnerable to manipulation by agents with deeper recursive capabilities. This imbalance, rooted in logic and the theory of recursive modelling frameworks, cannot be solved directly. We propose a computational framework called ℵ-IPOMDP, which augments the Bayesian inference of model-based RL agents with an anomaly detection algorithm and an out-of-belief policy. Our mechanism allows agents to realize that they are being deceived, even if they cannot understand how, and to deter opponents via a credible threat. We test this framework in both a mixed-motive and a zero-sum game. Our results demonstrate the ℵ-mechanism’s …

Just Be Yourself....But Only If You Are Like Us? A Social Identity Theory Cross-Cultural Meta-Analysis Of Authentic Leadership, Andrei A. Lux, Kevin B. Lowe, Patricio Duran, Darren K. Bharanitharan

Research outputs 2022 to 2026

We apply social identity theory (SIT) within a culturally endorsed implicit leadership theory (CLT) frame to model how cultural values shape relationships between authentic leadership and follower outcomes. We use meta-analytic methods to test hypotheses with data from 292 studies drawn from over 40 countries, comprised of 100,641 individuals, and including 35 attitudinal, behavioural, and performance outcomes. Meta-analytic regression of cultural values coded at the country level reveals a significant pattern of moderation effects across 42.9% of the correlates we tested, suggesting that authentic leadership theory is culturally embedded. The effects of authentic leadership vary to the extent that it …

Transforming The Public Plate: A Menu Of Options For Public Food Procurement That Nourishes People, Place And Planet, Leah Galvin, Emma-Kate Rose, Stephanie Godrich, Dheepa Jeyapalan, Joanna Horton

Research outputs 2022 to 2026

Public food procurement stands as one of the most powerful, yet chronically underutilised, policy levers available to Australian governments. Every day, publicly funded institutions – hospitals, residential aged care facilities, long day care, prisons, schools, defence facilities and community food programs – purchase and serve food to millions of Australians. These are not simply transactions. Collectively, these purchasing decisions shape production systems, supply chains, diets, livelihoods and environmental outcomes. They determine who thrives within our food system and who is left behind. Transforming the Public Plate is an Australian first. It provides the most comprehensive national picture to date of …

When Affect Is Not Episodic: Extending Affective Events Theory Under Sustained Oversight, Cathrine Frost, Andrei A. Lux, Peter Galvin

Research outputs 2022 to 2026

Affective Events Theory explains how workplace emotions arise from discrete events and shape attitudes and behaviour. Drawing on a phenomenological study of 29 employees and 13 managers working within oversight saturated supervisory contexts in the post–Royal Commission Australian financial services sector, this paper extends Affective Events Theory by examining how affective experience unfolds when accountability is continuous, and discretion is constrained. Across dual-cohort findings, affect was not primarily anchored to identifiable events that resolved over time. Instead, participants described emotion as persistent and cumulative, produced through ambiguity and emotional restraint, and circulating across supervisory roles. Employees reported sustained interpretive effort …

Barriers And Facilitators To Recruiting Older Adult Care Homeresidents Into Clinical Trials Of Medicines And Vaccines: A Scoping Review, Selvarani Subbarayan, Imogen A. Smith-Dodd, Gabriel Nicolson, Jennifer K. Burton, Janet T. Scott, Seshadri S. Vasan, Susan D. Shenkin, Roy L. Soiza, The Watch Consortium

Research outputs 2022 to 2026

Introduction: Excluding Care Home (CH) residents from clinical trials of medicines and vaccines has led to an evidence gap. Findings from younger adults may not be generalisable to CH residents with frailty and dementia. Therefore, it is essential to evaluate pharmacological treatments directly in CH residents to assess their safety and efficacy.

Methods: As part of the Widening Access to Trials in Care Homes project, we conducted a scoping review using Joanna Briggs Institute methodology to identify barriers and facilitators to recruiting CH residents into clinical trials of medicinal products. We searched EMBASE, MEDLINE, PsycINFO, CINAHL, and the Cochrane Library …

Strategizing Success: Advancing Women's Leadership And Careers In Healthcare Through A Positive Gain Spiral, Farveh Farivar, Andrei A. Lux, Nasim Salehi

Research outputs 2022 to 2026

Purpose – Women’s career progression in healthcare continues to lag men’s, particularly at senior leadership levels, limiting organizational performance and weakening leadership pipelines. This study applies Conservation of Resources (COR) theory’s positive gains cycle to examine how supportive organizational environments and human resource management practices can accelerate women’s advancement from early career stages to senior leadership. Design/methodology/approach – Using a social constructivist approach, we conducted 30 in-depth interviews with Australian healthcare leaders (20 female and 10 male) across multiple organizational levels. Thematic analysis identified the resources and interactions that enable sustained leadership progression for women. Findings – Four interconnected resources, …

A Brunerian Theoretical Framework For Ece: A Review Of Jerome Bruner’S Theoretical Contributions To Early Childhood Education, Samantha Wynne, Christine Robinson, Dee O’Connor

Research outputs 2022 to 2026

This paper presents the findings of an independent study, a systemic narrative literature review, that identifies and synthesises Jerome Bruner’s theoretical propositions related to young children’s knowledge construction and learning from birth to the early years of schooling. The research contributes the Brunerian Theoretical Framework, the first contextualised synthetisation of Brunerian theory as it relates to Early Childhood Education (ECE). Bruner’s postmodern constructivist and culturalist perspectives related to epistemology, theory, and pedagogy are explicated in the review of literature. Importantly, this paper explores Bruner’s culturalist provocation to centre epistemological inquiry in education. Bruner proposes that when educators adopt an epistemic …

Association Between Protein Intake From Animal And Plant Sources And The Presence Of Frailty In Community-Dwelling Australian Women, Trent Bozanich, Jack Dalla Via, Simone Radavelli-Bagatini, Cassandra Smith, Elsa Dent, Anthony Villani, Robin M. Daly, Michael Tieland, Jonathan M. Hodgson, Kun Zhu, Richard L. Prince, Marc Sim

Research outputs 2022 to 2026

We investigated the cross-sectional association between total, animal and plant protein intake with the presence of a multidimensional measure of frailty in older women. Participants included 1380 community-dwelling Australian women, mean (SD) age 75.1 (2.7) years. A validated food frequency questionnaire was used to determine total, plant, and animal protein intake. Frailty was assessed using a frailty index across numerous health domains (scored 0–1, ≥0.25 indicating frailty). Cross-sectional associations were analysed using multivariable-adjusted logistic regression models. In total, 275 (19.9%) women were identified as frail. A non-linear inverse association was observed between higher intakes of total protein and the odds …

Association Of Source-Specific Nitrate Intake With Inflammation And Cardiometabolic Health: A Cross-Sectional Study, Carolyn J. English, Catherine P. Bondonno, Liezhou Zhong, Anna Lohning, Nicola P. Bondonno, Dianne P. Reidlinger

Research outputs 2022 to 2026

This study aimed to explore whether health effects of dietary nitrate depend on its source, by investigating associations between plant and animal-sourced dietary nitrate groups with markers of inflammation and CVD risk factors. Among 100 non-smoking adults (mean age 49 ± 13 years, 31% male), dietary nitrate intake was assessed using food frequency questionnaire (n=100) and 3-day food diary (n=89), combined with nitrate food composition databases. Nitrate intake was classified into plant, naturally occurring animal and additive-permitted meat-sourced groups. Associations between source-dependent nitrate intakes and lipoprotein-associated phospholipase A2 (Lp-PLA2), C-reactive protein (CRP), fasting plasma lipids, anthropometry, and blood pressure were …

Beyond The Pandemic: How Covid-19 Highlighted The Need For Cross-Sector Healthcare Solutions For Young Australians Living With Adversity, Ennur Erbasi, Shannon Muir, Karen Mclean

Research outputs 2022 to 2026

We explored the perceived impacts of the COVID-19 pandemic on health and healthcare access among young people living with significant adversity in Victoria, Australia, using a convergent parallel mixed-methods design. Guided by a pragmatism epistemology, fifty-seven purposively sampled Victorian adolescents aged 15–19 years with lived experience of adversity completed a primarily quantitative online survey, and eight also participated in semi-structured interviews. Descriptive quantitative results indicated that a greater proportion of participants rated their mental health as fair or poor during COVID-19 (69%) compared to before the pandemic (40%). Similarly, more participants rated their physical health as fair or poor during …

Cohort Profile: The Resilient Minds National Study Of Mental Health And Cognitive Resilience In Community Dwelling Adults Aged 18 To 93, Kaarin J. Anstey, Brooke Brady, Lidan Zheng, Jana Koch, Md Hamidul Huque, Michelle K. Lupton, Ralph Martins, Daniel Ashworth, Erin Goddard, Nikki Anne Wilson, Claudia M. Hillenbrand, Ralf B. Loeffler, Maria Markoulli, Arun V. Krishnan, Tanya Layton, Ranmalee Eramudugolla

Research outputs 2022 to 2026

Purpose: The Resilient Minds (ReMind) cohort was established to investigate cognitive and mental health resilience across the life course, addressing a gap in longitudinal evidence about resilience. The study collected data on traditional medical and lifestyle risk factors for chronic disease, genetics, and a range of mental health and cognitive outcomes. It also aimed to explore contemporary contextual influences on resilience, including internet use, social engagement, environmental exposures, and life course adversities such as perceived discrimination. Participants: The cohort included 1,640 adults aged 18–93 years, recruited through social media and community groups, to participate in a fully remote, two-year health …

Designing And Evaluating Quality Transdisciplinary Work-Integrated Learning: Insights Into Practice, Denise Jackson, Claire Lambert, Sonja Coetzee

Research outputs 2022 to 2026

Higher education’s role in fostering innovation and enacting social change is increasingly important. Transdisciplinary Work-Integrated Learning (TWIL) offers opportunities to prepare students to address societal issues by transcending disciplinary boundaries and collaboratively tackling real-world global challenges. While extensive literature exists on established WIL models, research on the critical aspects of designing, implementing and evaluating impactful TWIL activities remains scarce. This paper draws together insights from 15 TWIL academics across 14 Australian universities, highlighting important design elements such as training for small group collaboration, open-ended projects, design thinking, sustained mentorship and reciprocal partnerships. Emerging challenges related to online delivery, teamwork, scalability, …

Diet, Gut Microbiota, And Intestinal Permeability: Emerging Mechanisms In Hypertension Pathogenesis, Esha Vashisht, Helen Nguyen, Francine Z. Marques, Matthew Snelson

Research outputs 2022 to 2026

Hypertension is a leading contributor to global morbidity and mortality, arising from the interplay of genetic and environmental risk factors together with the dysregulation of multiple physiological systems involved in blood pressure control. Recent advances have established the gut as a central regulator, implicating the intestinal microbiota and barrier integrity in the modulation of blood pressure. Alterations in the gut microbial consortium, along with changes in levels of metabolites produced by the microbiota, have been associated with blood pressure regulation in animal models and human studies. Key microbial metabolites, including short-chain fatty acids, trimethylamine-N-oxide, and bile acids influence endothelial function, …