Digital Commons Network^™

Adaptive Self-Attention For Enhanced Segmentation Of Adult Gliomas In Multi-Modal Mri, Evan P. Savaria, Jiangwen Sun

Computer Science Faculty Publications

Every year there are an estimated 80,000–90,000 new glioma cases, highlighting the need for reliable imaging-based decision support. Although deep learning has improved tumor sub-region segmentation, many state-of-the-art models fail to fully capture complementary information across T1, T1Gd, T2, and FLAIR MRI modalities and often operate as “black boxes,” limiting physician trust when precise delineation is critical for surgical planning, radiation targeting, and treatment monitoring. To address these limitations, we propose AIMS, an Adaptive Integrated Multi-Modal Segmentation framework that maintains modality-specific feature streams and employs adaptive self-attention within a hierarchical CNN-Transformer architecture to prioritize and fuse multi-modal MRI features. We …

Sage: Spatially Aware Gene Selection And Dual-View Embedding Fusion For Domain Identification In Spatial Transcriptomics, Yi He, Yunpei Xu, Liqing Ding, Hong-Dong Li, Yaohang Li, Shaokai Wang

Computer Science Faculty Publications

Despite enabling high-resolution mapping of gene expression within tissues, spatial transcriptomics (ST) still faces challenges in accurately segmenting spatial domains due to complex tissue architecture and limitations of current methods. Most approaches rely on local spatial priors, lack gene-level interpretability, and fall short in capturing structure-discriminative genes or long-range functional relationships, limiting their ability to resolve biologically meaningful architectures. We present Spatially Aware Gene selection and dual-view Embedding fusion (SAGE), a unified and reproducible framework for domain identification in spatial transcriptomics that combines topic-driven gene selection with dual-view embedding fusion to address these gaps. SAGE integrates non-negative matrix factorization (NMF)-based …

Application Paths Of Semantic Modeling In Financial Fraud Detection And Risk Identification, Victor P. Gauthier, Daniel S. Wu

Computer Science Faculty Publications

Financial fraud and risk pose significant threats to economic stability and individual well-being. Traditional detection methods often struggle to keep pace with increasingly sophisticated fraudulent schemes. Semantic modeling, which focuses on understanding the meaning and relationships within data, offers a promising avenue for enhancing fraud detection and risk identification. This review paper explores the application paths of semantic modeling in this domain. We begin with a historical overview of fraud detection techniques, highlighting the limitations of traditional approaches. Subsequently, we delve into core themes, including knowledge graph-based fraud detection and semantic rule-based inference for risk assessment. We then compare and …

Integration Of Hybrid Quantum-Neuromorphic Ai With Cloud, Edge, And High-Performance Computing Environments, Arun B. Prasad, Ajay Prasad, Dineshkumar Rajendran, Anurag Tiwari, T. Akilan, Islombek Khushvaktov

Computer Science Faculty Publications

The convergence of quantum computing, neuromorphic learning, and distributed cloud infrastructures has occurred very rapidly, and intelligent systems are now providing new opportunities, but the challenge of instability, complexity of orchestration, and noise sensitivity remains in the way of practical integration. The proposed work is based on a hybrid quantum and neuromorphic architecture, which is the integration of event-based neuromorphic adaptation and quantum-assisted global optimization, orchestrated by cloud-HPC. The architecture presents the thermodynamically regularized learning and resourceful task scheduling to the probabilistic search and the continuous local adaptation. Experimental evaluation across financial modeling, medical imaging, and physical system prediction shows …

Design And Analysis Of Modern Quantum Neural Network Architectures For Intelligent Systems, Lakshmi Chandrakanth Kasireddy, Prabhakara Rao Kapula, Dineshkumar Rajendran, Neha Bharani, Srikanth Pulipeti, Islombek Khushvaktov

Computer Science Faculty Publications

Quantum neural networks (QNNs) offer a principled pathway for integrating quantum computation with machine learning through superposition- and entanglement-based representations. This chapter proposes an architecture-aware design and evaluation framework for modern QNNs, emphasizing robustness and system feasibility alongside predictive performance. Multiple architectures variational QNNs, quantum convolutional neural networks, tensor-network hybrids, and fully quantum models—are assessed under a unified protocol. Experimental analysis shows that the proposed architecture-search–guided QNN achieves 91.8% classification accuracy and an F1-score of 0.914, outperforming fixed-template variational QNNs by approximately 5.6 percentage points. Under depolarizing noise with probability p = 0.10, the proposed model retains 85.3% accuracy, whereas …

Cognitive Prosthetic: An Ai-Enabled Multimodal System For Episodic Recall In Knowledge Work, Lawrence Obiuwevwi, Krzystof J. Rechowicz, Vikas Ashok, Sachin Shetty, Sampath Jayarathna

Computer Science Faculty Publications

Modern knowledge workplaces increasingly strain human episodic memory as individuals navigate fragmented attention, overlapping meetings, and multimodal information streams. Existing workplace tools provide partial support through note-taking or analytics but rarely integrate cognitive, physiological, and attentional context into retrievable memory representations. This paper presents the Cognitive Prosthetic Multimodal System (CPMS)—an AI-enabled proof-of-concept designed to support episodic recall in knowledge work through structured episodic capture and natural language retrieval. CPMS synchronizes speech transcripts, physiological signals, and gaze behavior into temporally aligned, JSON-based episodic records processed locally for privacy. Beyond data logging, the system includes a web-based retrieval interface that allows users …

Contextual Scaffolding And Self-Efficacy: Supporting Computer Skill Development Among Blind Learners In India, Akshay Kolgar Nayak, Yash Prakash, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

Inclusive computer literacy education efforts, broadening the participation of blind or visually impaired (BVI) individuals, have gained traction in recent years. Existing literature investigating these efforts primarily draws evidence from affluent Global North contexts, where accessibility resources and legal frameworks are relatively more mature. Little is known about the in-situ teaching and learning challenges faced by trainers and BVI students, respectively, in resource-constrained, multicultural Global South countries like India. To address this knowledge gap, we conducted a four-month contextual inquiry at two computer training centers catering to 94 BVI students in India. We notably observed a rigid, experience-driven training environment …

Modeling Joint Visual Attention In Naturalistic Dyadic Interactions, Kuushini Thennakoon, Yasasi Abeysinghe, Bhanuka Mahanama, Vikas Ashok, Sampath Jayarathna

Computer Science Faculty Publications

Joint visual attention (JVA) provides important insight into how individuals coordinate attention during social interaction. Egocentric eye tracking enables the study of JVA in natural, multi-user settings. This work presents a multi-stage framework to identify and analyze JVA using egocentric video and gaze data. The approach consists of three steps: spatiotemporal tube-based visual similarity, gaze-guided object detection, and attention pattern analysis using the ambient–focal coefficient K. Results show that object-focused collaborative activities exhibit high JVA, with object detection capturing higher joint attention than visual similarity, whereas conversation-based or independent activities show lower and more fragmented joint attention. Analysis of K …

Roles Of Cytokines In Modulating Trypanosoma Brucei Rhodesiense Infection Outcomes In Vervet Monkeys, Clarah Jebet, John Kibuthu Thuita, Daniel Masiga, Benedict Owino Orindi, John Oidho, Mark C. Field, Enock Matovu, Vincent Owino Adung’A

All Peer-Reviewed Publications

Introduction:

Human African trypanosomiasis (HAT), caused by Trypanosoma brucei rhodesiense, is categorized as acute due to rapid disease progression but presents varying clinical outcomes. Although the mechanisms underpinning differential clinical progression are poorly understood, both host and parasite factors are implicated. Therefore, we sought to elucidate roles of primate host factors in mediating varying T. b. rhodesiense infection outcomes.

Methods:

Here, we assessed the roles of selected host cytokines in disease progression using a tsetse-mediated infection in a non-human primate (NHP) vervet monkey model that closely mimics HAT and natural infection. We quantified eight cytokines, including TNF-α, IFN-γ, IL-10, IL-6, …

Full-Wave Modeling Of Rf Waves In Fusion Plasmas With Finite Element Method: Progress In Past Decades And Its Future Role, Syun'ichi Shiraiwa, Nicola Bertelli, Eun-Hwa Kim

Faculty Publications

No abstract provided.

Scripture Spotlight: What Was The Role Of The Scapegoat?, Roy Gane

Faculty Publications

No abstract provided.

Trained To Reach Immigrants, Denis Kaiser

Lake Union Herald

No abstract provided.

Contingent Value Of Coopetition In Business Clusters From A Resource-Based View: A Moderated-Mediation Model, George Vandyck, Christopher Agyapong Siaw, Jonas Aryee, Shikhar Bhaskar, Chiwuokem Nwoko, Rahul Govind

Plymouth Business School

This study examines how perceived cluster resource attractiveness (PCRA) shapes coopetition among co-located firms and how coopetition translates those resource perceptions into knowledge sharing and innovation. Building on the resource-based view, we model coopetition as the mechanism through which managers leverage valuable, unique, and complementary cluster resources into firm outcomes, and we theorize that engagement mode in cluster activities conditions this translation. Using survey data from 221 firms in a business cluster, we estimate a moderated-mediation model with regression and corroborate the results with a latent-variable SEM robustness check. Findings show that PCRA increases coopetition, and coopetition in turn enhances …

Agglomeration Dynamics And Firm Typologies In African Port-Industrial Clusters: Evidence From The Port Of Tema, Ghana, George Kobina Vandyck, Jonas Aryee, George Acheampong, Annette Skovsted Hansen

Plymouth Business School

Firm-level behaviour within port-industrial clusters shapes regional competitiveness, yet empirical evidence from Sub-Saharan Africa remains scarce. This study analyses how firms within the Port of Tema industrial cluster in Ghana engage with collaboration, resource access, and innovation dynamics, applying evolutionary, institutional, and network-relational perspectives. A cross-sectional survey of 278 firms within a 10-km radius of the port was analysed using K-means clustering and validated through ANOVA and Chi-square tests. Four firm typologies were identified: Collaborative Integrators, who leverage cooperation to achieve superior market and financial access; Dynamic Coopetitors, balancing competitive and cooperative ties; Competitive Innovators, maintaining selective engagement; and Isolated …

Can The 2025 Nobel Prizes In Physics And Economics Inspire A “Quantum” Turn In Tourism Research?, Waqas Ali

Plymouth Business School

No abstract provided.

Implementación Y Evaluación De Un Seminario De Liderazgo Para Dirigentes De La Iglesia Adventista Jardín En Neiva, Colombia, Andrés Palomino

Doctor of Ministry Projects

Problem

A preliminary study, consisting of exploratory dialogues conducted with the church elders, revealed that the leaders of the Seventh-day Adventist Church of Jardín, Neiva, faced limitations in the development of their local leadership. Although the leaders received instruction regarding the specific functions of their departments, they lacked knowledge in broader aspects of leadership, such as biblical leadership and contemporary perspectives (nature, models, styles, and theories). This deficiency limited the effective leadership of the church departments.

Methodology

The present study was framed within the field of applied practical theology, as it intentionally sought to intervene in ministerial practice and evaluate …

Desarrollo E Implementación De Un Seminario Sobre Comunicación Para Parejas De La Iglesia Adventista Del Séptimo Día Hispana De West Suburban En Villa Park, Illinois, Nelson Salazar

Doctor of Ministry Projects

Problem

The 184-member West Suburban Hispanic Seventh-day Adventist Church has no record of holding a communication seminar for couples in the congregation. Several church members have requested that training be provided to the church's forty-five couples. The benefits that the seminar on couples’ communication can confer have the potential to foster unity in marriages and homes. The lessons learned from the implementation of this project can also serve as a reference for other congregations with similar realities.

Methodology

For the development and implementation of this training seminar, after obtaining the necessary administrative permits, the author examined the topic of couple …

Programa De Mentoría Basado En El Proceso De Discipulado Para Líderes De La Iglesia Adventista Del Séptimo Día Hispana De Rogers Heights, En Wyoming, Michigan, Darling Ayala

Doctor of Ministry Projects

Problem

Making disciples is the mission given by Jesus Christ to His followers; this must be the primary objective of the Christian life. Therefore, the church must carry out activities that follow the model of biblical discipleship in order to attract prospective disciples. Since its formation in 2012, the Hispanic Church of Rogers Heights has not experienced sustainable numerical growth because it did not implement a discipleship program or an intentional mentoring plan. The progressive loss of members, the lack of missionary commitment among its leaders, limited resources, and the low number of new disciples in proportion to the number …

Desarrollo E Implementación De Un Seminario Sobre La Oración Y El Ayuno Para El Reavivamiento Espiritual De La Iglesia Adventista Del Séptimo Día Hispana De Milwaukie, Oregon, Marlon Batz

Doctor of Ministry Projects

Problem

The Hispanic Seventh-day Adventist Church of Milwaukie (IASDM) demonstrates the need for a spiritual revival among its members. An initial diagnosis, conducted with the Daily Spiritual Experience Scale (DSES) by Lynn Underwood, shows reduced levels in core aspects of spiritual life. For example, in response to the item "During worship, or at other times when connecting with God, I feel joy which lifts me out of my daily concerns”, only 23.6% of participants indicate experiencing this sensation every day, and just 7.8% report feeling it several times a day. In the item "I find comfort in my religion or …

Lower Suicidal Ideation Linked To Easier Access To Urban Green Spaces During The Covid-19 Pandemic: A Nationwide Study In Japan, Zheng Xian, Tomoki Nakaya, Clive E. Sabel, Ryo Okubo, Kun Liu, Jinguang Zhang, Takahiro Tabuchi

School of Geography, Earth and Environmental Sciences

Urban green spaces (UGSs) have been linked to improved mental health and lower suicide rates, yet their protective role during large-scale crises remains underexplored. We examined associations of UGS accessibility with long-term and pandemic induced new-onset suicidal ideation during the early phase of the COVID-19 pandemic in urban Japan, using data from a nationwide health survey of 17,376 participants (August 2020). Modified Poisson regression models estimated prevalence ratios (PRs) for suicidal ideation by UGS accessibility (area, number, and type) within 5, 10, and 15-minute walking thresholds from home, controlling for individual and area-level confounders. UGS accessibility exhibited dose-response relationships with …

Direct And Indirect Metal Contamination Of Estuarine Sediments By Boat Paint Particles, Andrew Turner, Ho Kwan Cheung

School of Geography, Earth and Environmental Sciences

Surface and subsurface estuarine sediments close to a cluster of abandoned boats have been fractionated (between <250 and 5000 μm) and analysed microscopically for paint particles. Paints were encountered in all samples, with concentrations calculated for whole sediment samples up to 1450 per kg (dry weight). X-ray fluorescence (XRF) analysis of paint particles retained by the coarsest (>5000 μm) size fraction revealed heterogeneous concentrations of Ba, Cu, Pb, Sn and Zn that reflect pigments and antifoulants used in various recent and historical antifouling and above waterline boat paints. Analysis of sediments by XRF revelated heterogeneous distributions of these metals between locations, size fractions and depths, and among replicate measurements at different positions of the same sample. Consequently, no relationship with grain size (evaluated using Rb as a proxy) was evident and concentrations often greatly exceeded predicted effect levels for sediments. Re-analysis …

Quantifying The Response Of Bankfull Channel Width To Active Faulting In The Qianhe Graben On The Southwest Margin Of Ordos Block, China, Zhiheng Liu, Sarah Boulton, Suiping Zhou, Jianhua Guo, Tingting Wu, Wenjie Zhang, Ling Han

School of Geography, Earth and Environmental Sciences

River longitudinal profiles have been widely used to quantify the transient landscape response to active faulting, but the fluvial cross-section is often ignored, yet width can also reveal river incision and tectonic activity. Channel width responds to tectonic forcing through flow concentration effects resulting in channel narrowing where vertical incision dominates during uplift acceleration. Here we employ a novel bankfull channel width extraction method using Landsat and ZY-3 satellite images, and SRTM DEM data to evaluate the cross-section landscape response to active faulting in the Qianhe Graben of southwest Ordos, China. Although some areas are difficult to access (e.g., thick …

Presence And Characteristics Of Plastics And Microplastics On The Seabed Of The Western English Channel, Faye Read, Andrew Turner

School of Geography, Earth and Environmental Sciences

Little is known about the presence, distribution, origins and characteristics of plastic litter and microplastics on the ocean floor. In this study, plastics trawled from the bed of the western English Channel have been categorised and analysed by a variety of optical and spectroscopic techniques. A total of 90 plastic samples were classified, in descending order of abundance, as food-drink packaging, unknown, homeware, military and fishing. Most samples showed varying degrees of weathering (e.g., discolouration, distortion, cracking, fragmentation) and were visibly fouled by calcareous deposits. The majority of samples were constructed of polymers of negative buoyancy (e.g., polyamides, polyethylene terephthalate …

Long-Term Evaluation Of The Energy Consumption Of 100 Energy-Efficient Buildings In Austria, Thomas Roßkopf-Nachbaur, Günter Lang, Martin Ploß, Markus Lang, Andreas Peter, Tobias Hatt, Diana Ürge-Vorsatz, Souran Chatterjee, Luisa F. Cabeza

School of Geography, Earth and Environmental Sciences

In 2019, buildings greenhouse gas (GHG) emissions accounted for 21 % of global emissions, therefore regions such as Europe have strong policies to decrease such emissions. The literature shows different examples simulating energy refurbishment of buildings or districts where an important GHG reduction can be achieved, but there is a clear gap on real measurements of exemplary buildings. This paper shows an assessment of more than 100 energy-efficient buildings in Austria, showing that this GHG emissions reduction is really possible. The paper evaluates residential and non-residential buildings, where the energy consumption was 50 % below the consumption of typical multi-apartment …

Who Seeks Help? Characteristics Of Doctors Accessing Mental Health Support In England: 4-Year National Review, Rohit Shankar

Peninsula Medical School

BackgroundMental health difficulties affect the well-being of doctors and compromise the delivery of healthcare. However, large-scale data on doctors’ mental health needs are limited.AimsDescribe patterns of self-referrals for mental health support among doctors in England and explore associations with demographic factors, speciality, neurodevelopmental and mental health indicators.MethodObservational study using data from doctors who self-referred for mental health difficulties to a national service in England over a 4-year period. Logistic regression was used to explore associations between speciality and mental health indicators.ResultsOf the 16 815 doctors who self-referred during the study period, 80% were under the age of 49 and 70.6% …

Microbial Collagenase Activity Is Linked To Oral–Gut Translocation In Advanced Chronic Liver Disease, Shen Jin, Aurelie Cenier, Daniela Wetzel, Bethlehem Arefaine, Mar Moreno-Gonzalez, Marilena Stamouli, Merianne Mohamad, Mariia Lupatsii, Emilio Ríos, Sunjae Lee, Ane Zamalloa, Shilpa Chokshi, Adil Mardinoglu, Saeed Shoaie, Naiara Beraza, Vishal C. Patel, Melanie Schirmer

Peninsula Medical School

Microbiome perturbations are associated with advanced chronic liver disease (ACLD), but how microorganisms contribute to disease mechanisms is unclear. Here we analysed metagenomes of paired saliva and faecal samples from an ACLD cohort of 86 individuals, plus 2 control groups of 52 healthy individuals and 14 patients with sepsis. We identified highly similar oral and gut bacterial strains, including Veillonella and Streptococcus spp., which increased in absolute abundance in the gut of patients with ACLD compared with controls. These microbial translocators uniquely share a prtC gene encoding a collagenase-like proteinase, and its faecal abundance was a robust ACLD biomarker (area …

Global Manta And Devil Ray Population Declines: Closing Policy And Management Gaps To Reduce Fisheries Mortality, Betty J.L. Laglbauer, Nidhi G. D'Costa, Joshua D. Stewart, Marta D. Palacios, Melissa Cronin, Daniel Fernando, Nerea Lezama-Ochoa, Asia O. Armstrong, Rima W. Jabado, Sarah Fowler, Julia M. Lawson, Olga Koubrak, Jefferson Murua, Thanda Ko Gyi, Divya Karnad, Mayuri Chopra, Giuseppe Notarbartolo-Di-Sciara, Joshua Rambahiniarison, Don Croll, Stefany Rojas, Abdulaziz Fahmi, Joanna L. Harris, Alifa Binthe Haque, Hilario Murua, Juan Carlos Pérez-Jiménez, Emily Humble, Ellen Barrowclift, Muhammad G. Salim, Godefroy De Bruyne, Issah Seidu

School of Biological and Marine Sciences

Significant progress has been made in advancing priority actions to conserve manta and devil rays, yet implementation and enforcement of protective measures often fall short, leaving most mobulid populations at risk of overfishing. Drawing on a literature review, fisheries databases, agency reports, and expert interviews, we assess global trends in mobulid catch and mortality. We examine both targeted and incidental catch, in small (<15 m, ‘SV’) and large (>15 m, ‘LV’) vessel fisheries to identify hotspots with the highest risk of fisheries-related mortality and population decline. We estimate global fisheries catch at 264,520 (184,407–344,987) mobulids per year, with SV fisheries accounting for 87 % …

Insights Into The Petrogenesis Of Alkalic, Shonkinitic Magmas From The Adel Hill Volcanic Field, Montana, Kenneth L. Brown, C. L. Mcleod, M. L. Lytle, T. J. Cracas, B. J. Shaulis, M. Loocke

Geology and Environmental Geoscience Faculty Publications

Shonkinites are rare alkali-rich igneous rocks found in the geological record from the Precambrian to the Eocene. This study investigates the Upper Cretaceous shonkinites from the Adel Hills Volcanic Field (AHVF), central Montana. The AHVF shonkinites are porphyritic with large, euhedral to subhedral phenocrysts of diopside that exhibit sector zoning. Other major mineral phases include plagioclase, sanidine, and secondary zeolites. Minor and accessory phases identified with SEM-EDS include magnetite, apatite, rare ilmenite and pyrite, and secondary calcite. Bulk rock SiO2 ranges from 47 to 49 wt% with Na2O + K2O varying from 5.50 to 7.34 wt% within that silica range. …

The Impact Of Fixation Method And Surgical Approach On Outcomes Following Hip Hemiarthroplasty For Femoral Neck Fracture, Brian D Rust, Mitchel R Obey, Jenna-Leigh Wilson, Christopher M Mcandrew, Marschall B Berkes

2020-Current year OA Pubs

INTRODUCTION: Hip hemiarthroplasty is commonly performed for displaced femoral neck fractures in older adults, with implants placed either cemented or uncemented. While cemented fixation offers immediate stability, uncemented fixation reduces operative time and pulmonary complications. Large single-center analyses comparing these techniques remain limited, and this study aims to assess this.

METHODS: We conducted a retrospective case-control study of 634 adult patients undergoing hip hemiarthroplasty at a single Level 1 trauma center from 2019 to 2025. Patients were classified by cemented (n=403) or uncemented (n=231) fixation and further stratified by surgical approach (anterolateral vs posterior). Outcomes included length of stay, postoperative …

A Microenvironment-Driven Hla-Ii-Associated Insulin Neoantigen Elicits Persistent Memory T Cell Activation In Diabetes, Neetu Srivastava, Anthony N Vomund, Rongzhen Yu, Orion J Peterson, Yuqing Yang, David P Turicek, Omar Abousaway, Tiandao Li, Pamela Stone, Aisha Ansar, Rima Melhem, Bo Zhang, Chang Liu, Hao Hu, Chyi-Song Hsieh, Laura Campisi, Emil R Unanue, Ana Maria Arbelaez, Cheryl F Lichti, Xiaoxiao Wan, Et Al.

2020-Current year OA Pubs

The antigenic landscape of autoimmune diabetes reflects a failure to preserve self-tolerance, yet how novel neoantigens emerge in humans remains incompletely understood. Here we designed an immunopeptidomics-based approach to probe HLA-II-bound, islet-derived neoepitopes in patients with type 1 diabetes. We uncovered a Cys→Ser transformation, conserved between mice and humans, that reshapes autoreactivity to insulin at the single-residue level. This transformation, which we call C19S, arises from oxidative remodeling of insulin in stressed pancreatic islets and also occurs in cytokine-activated antigen-presenting cells, contributing to a feed-forward loop of neoepitope formation and presentation. Despite involving just one amino acid, C19S is recognized …